1121267:CCUN RS08295
gene id: 1121267:CCUN_RS08295
uniprot id: A0A1W6BYU8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1121267:CCUN RS03025
gene id: 1121267:CCUN_RS03025
uniprot id: A0A1W6BW06
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1121267:CCUN RS01880
gene id: 1121267:CCUN_RS01880
uniprot id: A0A1W6BVB9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1121267:CCUN RS04880
gene id: 1121267:CCUN_RS04880
uniprot id: A0A1W6BWX1
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS06070
gene id: 1121267:CCUN_RS06070
uniprot id: A0A1W6BXK5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS04395
gene id: 1121267:CCUN_RS04395
uniprot id: A0A1W6BWP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1121267:CCUN RS04480
gene id: 1121267:CCUN_RS04480
uniprot id: A0A1W6BWL3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1121267:CCUN RS01070
gene id: 1121267:CCUN_RS01070
uniprot id: A0A1W6BUY4
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS00065
gene id: 1121267:CCUN_RS00065
uniprot id: A0A1W6BUB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1121267:CCUN RS00090
gene id: 1121267:CCUN_RS00090
uniprot id: A0A1W6BUD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1121267:CCUN RS04770
gene id: 1121267:CCUN_RS04770
uniprot id: A0A1W6BWW0
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1121267:CCUN RS08105
gene id: 1121267:CCUN_RS08105
uniprot id: A0A1W6BYP2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS04370
gene id: 1121267:CCUN_RS04370
uniprot id: A0A1W6BWL8
names: Similarity
messages: Belongs to the ArsC family.

1121267:CCUN RS00215
gene id: 1121267:CCUN_RS00215
uniprot id: A0A1W6BUD9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1121267:CCUN RS08865
gene id: 1121267:CCUN_RS08865
uniprot id: A0A1W6BZ26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1121267:CCUN RS04315
gene id: 1121267:CCUN_RS04315
uniprot id: A0A1W6BWL6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1121267:CCUN RS01540
gene id: 1121267:CCUN_RS01540
uniprot id: A0A1W6BV37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1121267:CCUN RS01190
gene id: 1121267:CCUN_RS01190
uniprot id: A0A1W6BV03
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1121267:CCUN RS06010
gene id: 1121267:CCUN_RS06010
uniprot id: A0A1W6BXF9
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS04095
gene id: 1121267:CCUN_RS04095
uniprot id: A0A1W6BWG5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS04350
gene id: 1121267:CCUN_RS04350
uniprot id: A0A1W6BWM2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1121267:CCUN RS05610
gene id: 1121267:CCUN_RS05610
uniprot id: A0A1W6BXC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

1121267:CCUN RS00310
gene id: 1121267:CCUN_RS00310
uniprot id: A0A1W6BUG2
names: Similarity
messages: Belongs to the GSP E family.

1121267:CCUN RS08445
gene id: 1121267:CCUN_RS08445
uniprot id: A0A1W6BYT4
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1121267:CCUN RS07415
gene id: 1121267:CCUN_RS07415
uniprot id: A0A1W6BYA6
names: Similarity
messages: Belongs to the HypE family.

1121267:CCUN RS01590
gene id: 1121267:CCUN_RS01590
uniprot id: A0A1W6BV47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1121267:CCUN RS00195
gene id: 1121267:CCUN_RS00195
uniprot id: A0A1W6BUF5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1121267:CCUN RS03220
gene id: 1121267:CCUN_RS03220
uniprot id: A0A1W6BW35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1121267:CCUN RS04020
gene id: 1121267:CCUN_RS04020
uniprot id: A0A1W6BWI9
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS07930
gene id: 1121267:CCUN_RS07930
uniprot id: A0A1W6BYQ6
names: Similarity
messages: Belongs to the hemerythrin family.

1121267:CCUN RS05365
gene id: 1121267:CCUN_RS05365
uniprot id: A0A1W6BX66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1121267:CCUN RS01175
gene id: 1121267:CCUN_RS01175
uniprot id: A0A1W6BUX7
names: Similarity
messages: Belongs to the UPF0102 family.

1121267:CCUN RS02425
gene id: 1121267:CCUN_RS02425
uniprot id: A0A1W6BVH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1121267:CCUN RS04000
gene id: 1121267:CCUN_RS04000
uniprot id: A0A1W6BWC7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1121267:CCUN RS04015
gene id: 1121267:CCUN_RS04015
uniprot id: A0A1W6BWD0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1121267:CCUN RS03330
gene id: 1121267:CCUN_RS03330
uniprot id: A0A1W6BVZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1121267:CCUN RS03385
gene id: 1121267:CCUN_RS03385
uniprot id: A0A1W6BW54
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS04750
gene id: 1121267:CCUN_RS04750
uniprot id: A0A1W6BWV3
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS05915
gene id: 1121267:CCUN_RS05915
uniprot id: A0A1W6BXG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1121267:CCUN RS02685
gene id: 1121267:CCUN_RS02685
uniprot id: A0A1W6BVM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121267:CCUN RS04670
gene id: 1121267:CCUN_RS04670
uniprot id: A0A1W6BWQ6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1121267:CCUN RS09135
gene id: 1121267:CCUN_RS09135
uniprot id: A0A1W6BZ63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1121267:CCUN RS05190
gene id: 1121267:CCUN_RS05190
uniprot id: A0A1W6BX41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1121267:CCUN RS04495
gene id: 1121267:CCUN_RS04495
uniprot id: A0A1W6BWM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1121267:CCUN RS06795
gene id: 1121267:CCUN_RS06795
uniprot id: A0A1W6BXZ3
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS09320
gene id: 1121267:CCUN_RS09320
uniprot id: A0A1W6BZA1
names: Similarity
messages: Belongs to the asparaginase 1 family.

1121267:CCUN RS08075
gene id: 1121267:CCUN_RS08075
uniprot id: A0A1W6BYN6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1121267:CCUN RS00895
gene id: 1121267:CCUN_RS00895
uniprot id: A0A1W6BUQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1121267:CCUN RS08080
gene id: 1121267:CCUN_RS08080
uniprot id: A0A1W6BYL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1121267:CCUN RS05170
gene id: 1121267:CCUN_RS05170
uniprot id: A0A1W6BX01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1121267:CCUN RS01520
gene id: 1121267:CCUN_RS01520
uniprot id: A0A1W6BV45
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1121267:CCUN RS03020
gene id: 1121267:CCUN_RS03020
uniprot id: A0A1W6BVV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1121267:CCUN RS08375
gene id: 1121267:CCUN_RS08375
uniprot id: A0A1W6BYS1
names: Similarity
messages: Belongs to the catalase family.

1121267:CCUN RS04285
gene id: 1121267:CCUN_RS04285
uniprot id: A0A1W6BWL0
names: Similarity
messages: Belongs to the glutamine synthetase family.

1121267:CCUN RS00140
gene id: 1121267:CCUN_RS00140
uniprot id: A0A1W6BUF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1121267:CCUN RS06735
gene id: 1121267:CCUN_RS06735
uniprot id: A0A1W6BXY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1121267:CCUN RS03525
gene id: 1121267:CCUN_RS03525
uniprot id: A0A1W6BW48
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121267:CCUN RS08265
gene id: 1121267:CCUN_RS08265
uniprot id: A0A1W6BYR0
names: Similarity
messages: Belongs to the peptidase S49 family.

1121267:CCUN RS00150
gene id: 1121267:CCUN_RS00150
uniprot id: A0A1W6BUD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1121267:CCUN RS08895
gene id: 1121267:CCUN_RS08895
uniprot id: A0A1W6BZ84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1121267:CCUN RS06495
gene id: 1121267:CCUN_RS06495
uniprot id: A0A1W6BXT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1121267:CCUN RS04260
gene id: 1121267:CCUN_RS04260
uniprot id: A0A1W6BWN1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS03945
gene id: 1121267:CCUN_RS03945
uniprot id: A0A1W6BWD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1121267:CCUN RS04070
gene id: 1121267:CCUN_RS04070
uniprot id: A0A1W6BWK3
names: Caution
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1121267:CCUN RS01845
gene id: 1121267:CCUN_RS01845
uniprot id: A0A1W6BVB2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS07495
gene id: 1121267:CCUN_RS07495
uniprot id: A0A1W6BYA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1121267:CCUN RS04375
gene id: 1121267:CCUN_RS04375
uniprot id: A0A1W6BWJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1121267:CCUN RS06915
gene id: 1121267:CCUN_RS06915
uniprot id: A0A1W6BY10
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS00845
gene id: 1121267:CCUN_RS00845
uniprot id: A0A1W6BUR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1121267:CCUN RS04460
gene id: 1121267:CCUN_RS04460
uniprot id: A0A1W6BWL1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1121267:CCUN RS08370
gene id: 1121267:CCUN_RS08370
uniprot id: A0A1W6BYU0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S16 family.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1121267:CCUN RS01170
gene id: 1121267:CCUN_RS01170
uniprot id: A0A1W6BV04
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1121267:CCUN RS08195
gene id: 1121267:CCUN_RS08195
uniprot id: A0A1W6BYS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1121267:CCUN RS00390
gene id: 1121267:CCUN_RS00390
uniprot id: A0A1W6BUI2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1121267:CCUN RS08715
gene id: 1121267:CCUN_RS08715
uniprot id: A0A1W6BYZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1121267:CCUN RS07985
gene id: 1121267:CCUN_RS07985
uniprot id: A0A1W6BYK5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1121267:CCUN RS00040
gene id: 1121267:CCUN_RS00040
uniprot id: A0A1W6BUC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1121267:CCUN RS08245
gene id: 1121267:CCUN_RS08245
uniprot id: A0A1W6BYT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1121267:CCUN RS00385
gene id: 1121267:CCUN_RS00385
uniprot id: A0A1W6BUI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1121267:CCUN RS03785
gene id: 1121267:CCUN_RS03785
uniprot id: A0A1W6BWC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1121267:CCUN RS08960
gene id: 1121267:CCUN_RS08960
uniprot id: A0A1W6BZ40
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Homodimer.

1121267:CCUN RS04025
gene id: 1121267:CCUN_RS04025
uniprot id: A0A1W6BWF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane

1121267:CCUN RS07260
gene id: 1121267:CCUN_RS07260
uniprot id: A0A1W6BYC4
names: Similarity
messages: Belongs to the cytochrome P450 family.

1121267:CCUN RS08975
gene id: 1121267:CCUN_RS08975
uniprot id: A0A1W6BZ57
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1121267:CCUN RS04160
gene id: 1121267:CCUN_RS04160
uniprot id: A0A1W6BWJ6
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1121267:CCUN RS09015
gene id: 1121267:CCUN_RS09015
uniprot id: A0A1W6BZ75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1121267:CCUN RS00335
gene id: 1121267:CCUN_RS00335
uniprot id: A0A1W6BUG9
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1121267:CCUN RS04125
gene id: 1121267:CCUN_RS04125
uniprot id: A0A1W6BWH8
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1121267:CCUN RS02970
gene id: 1121267:CCUN_RS02970
uniprot id: A0A1W6BVZ7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1121267:CCUN RS09280
gene id: 1121267:CCUN_RS09280
uniprot id: A0A1W6BZG8
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1121267:CCUN RS06115
gene id: 1121267:CCUN_RS06115
uniprot id: A0A1W6BXK0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1121267:CCUN RS08125
gene id: 1121267:CCUN_RS08125
uniprot id: A0A1W6BYN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1121267:CCUN RS04105
gene id: 1121267:CCUN_RS04105
uniprot id: A0A1W6BWI3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS05220
gene id: 1121267:CCUN_RS05220
uniprot id: A0A1W6BX13
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1121267:CCUN RS00085
gene id: 1121267:CCUN_RS00085
uniprot id: A0A1W6BUC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1121267:CCUN RS07435
gene id: 1121267:CCUN_RS07435
uniprot id: A0A1W6BYB7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1121267:CCUN RS01245
gene id: 1121267:CCUN_RS01245
uniprot id: A0A1W6BUX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121267:CCUN RS09495
gene id: 1121267:CCUN_RS09495
uniprot id: A0A1W6BZE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1121267:CCUN RS09345
gene id: 1121267:CCUN_RS09345
uniprot id: A0A1W6BZD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121267:CCUN RS00345
gene id: 1121267:CCUN_RS00345
uniprot id: A0A1W6BUJ6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1121267:CCUN RS08575
gene id: 1121267:CCUN_RS08575
uniprot id: A0A1W6BZ01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1121267:CCUN RS08225
gene id: 1121267:CCUN_RS08225
uniprot id: A0A1W6BYR1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1121267:CCUN RS06475
gene id: 1121267:CCUN_RS06475
uniprot id: A0A1W6BXS3
names: Similarity
messages: Belongs to the hemerythrin family.

1121267:CCUN RS01640
gene id: 1121267:CCUN_RS01640
uniprot id: A0A1W6BV93
names: Cofactor
names: Similarity
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.

1121267:CCUN RS01675
gene id: 1121267:CCUN_RS01675
uniprot id: A0A1W6BV81
names: Similarity
messages: Belongs to the MotB family.

1121267:CCUN RS00805
gene id: 1121267:CCUN_RS00805
uniprot id: A0A1W6BUS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1121267:CCUN RS00705
gene id: 1121267:CCUN_RS00705
uniprot id: A0A1W6BUP2
names: Similarity
messages: Belongs to the VgrG protein family.

1121267:CCUN RS00410
gene id: 1121267:CCUN_RS00410
uniprot id: A0A1W6BUI4
names: Similarity
messages: Belongs to the peptidase C40 family.

1121267:CCUN RS03510
gene id: 1121267:CCUN_RS03510
uniprot id: A0A1W6BW83
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1121267:CCUN RS06295
gene id: 1121267:CCUN_RS06295
uniprot id: A0A1W6BXQ8
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS04825
gene id: 1121267:CCUN_RS04825
uniprot id: A0A1W6BX02
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1121267:CCUN RS01080
gene id: 1121267:CCUN_RS01080
uniprot id: A0A1W6BUV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1121267:CCUN RS05200
gene id: 1121267:CCUN_RS05200
uniprot id: A0A1W6BX05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1121267:CCUN RS03070
gene id: 1121267:CCUN_RS03070
uniprot id: A0A1W6BVY8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1121267:CCUN RS04935
gene id: 1121267:CCUN_RS04935
uniprot id: A0A1W6BWY4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1121267:CCUN RS07750
gene id: 1121267:CCUN_RS07750
uniprot id: A0A1W6BYH6
names: Similarity
messages: Belongs to the GSP E family.

1121267:CCUN RS06865
gene id: 1121267:CCUN_RS06865
uniprot id: A0A1W6BXZ4
names: Similarity
messages: Belongs to the peptidase A31 family.

1121267:CCUN RS04500
gene id: 1121267:CCUN_RS04500
uniprot id: A0A1W6BWR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1121267:CCUN RS00975
gene id: 1121267:CCUN_RS00975
uniprot id: A0A1W6BUU4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1121267:CCUN RS07715
gene id: 1121267:CCUN_RS07715
uniprot id: A0A1W6BYL9
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1121267:CCUN RS06995
gene id: 1121267:CCUN_RS06995
uniprot id: A0A1W6BY27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1121267:CCUN RS00450
gene id: 1121267:CCUN_RS00450
uniprot id: A0A1W6BUJ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1121267:CCUN RS08330
gene id: 1121267:CCUN_RS08330
uniprot id: A0A1W6BYY7
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS03645
gene id: 1121267:CCUN_RS03645
uniprot id: A0A1W6BW90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1121267:CCUN RS02955
gene id: 1121267:CCUN_RS02955
uniprot id: A0A1W6BVX3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS01910
gene id: 1121267:CCUN_RS01910
uniprot id: A0A1W6BVB4
names: Similarity
messages: Belongs to the UbiD family.

1121267:CCUN RS00565
gene id: 1121267:CCUN_RS00565
uniprot id: A0A1W6BUL2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1121267:CCUN RS00940
gene id: 1121267:CCUN_RS00940
uniprot id: A0A1W6BUU6
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS02990
gene id: 1121267:CCUN_RS02990
uniprot id: A0A1W6BVY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1121267:CCUN RS04440
gene id: 1121267:CCUN_RS04440
uniprot id: A0A1W6BWK9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS02035
gene id: 1121267:CCUN_RS02035
uniprot id: A0A1W6BVI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1121267:CCUN RS03235
gene id: 1121267:CCUN_RS03235
uniprot id: A0A1W6BW31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1121267:CCUN RS04215
gene id: 1121267:CCUN_RS04215
uniprot id: A0A1W6BWK6
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS00965
gene id: 1121267:CCUN_RS00965
uniprot id: A0A1W6BUT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1121267:CCUN RS05260
gene id: 1121267:CCUN_RS05260
uniprot id: A0A1W6BX45
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1121267:CCUN RS01075
gene id: 1121267:CCUN_RS01075
uniprot id: A0A1W6BUW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1121267:CCUN RS04925
gene id: 1121267:CCUN_RS04925
uniprot id: A0A1W6BX27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1121267:CCUN RS06110
gene id: 1121267:CCUN_RS06110
uniprot id: A0A1W6BXI0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1121267:CCUN RS05905
gene id: 1121267:CCUN_RS05905
uniprot id: A0A1W6BXG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1121267:CCUN RS02805
gene id: 1121267:CCUN_RS02805
uniprot id: A0A1W6BVV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121267:CCUN RS00350
gene id: 1121267:CCUN_RS00350
uniprot id: A0A1W6BUH9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1121267:CCUN RS01970
gene id: 1121267:CCUN_RS01970
uniprot id: A0A1W6BVE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1121267:CCUN RS00185
gene id: 1121267:CCUN_RS00185
uniprot id: A0A1W6BUE5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS07970
gene id: 1121267:CCUN_RS07970
uniprot id: A0A1W6BYL6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS03125
gene id: 1121267:CCUN_RS03125
uniprot id: A0A1W6BVX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1121267:CCUN RS05350
gene id: 1121267:CCUN_RS05350
uniprot id: A0A1W6BX30
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1121267:CCUN RS07145
gene id: 1121267:CCUN_RS07145
uniprot id: A0A1W6BY47
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1121267:CCUN RS00415
gene id: 1121267:CCUN_RS00415
uniprot id: A0A1W6BUK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1121267:CCUN RS00290
gene id: 1121267:CCUN_RS00290
uniprot id: A0A1W6BUG4
names: Similarity
messages: Belongs to the class-I fumarase family.

1121267:CCUN RS09185
gene id: 1121267:CCUN_RS09185
uniprot id: A0A1W6BZA4
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1121267:CCUN RS00075
gene id: 1121267:CCUN_RS00075
uniprot id: A0A1W6BUD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1121267:CCUN RS05395
gene id: 1121267:CCUN_RS05395
uniprot id: A0A1W6BX79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1121267:CCUN RS06515
gene id: 1121267:CCUN_RS06515
uniprot id: A0A1W6BXP7
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1121267:CCUN RS05230
gene id: 1121267:CCUN_RS05230
uniprot id: A0A1W6BX34
names: Similarity
messages: Belongs to the AdoMet synthase family.

1121267:CCUN RS02070
gene id: 1121267:CCUN_RS02070
uniprot id: A0A1W6BVG3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1121267:CCUN RS00955
gene id: 1121267:CCUN_RS00955
uniprot id: A0A1W6BUU3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1121267:CCUN RS08150
gene id: 1121267:CCUN_RS08150
uniprot id: A0A1W6BYQ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS05555
gene id: 1121267:CCUN_RS05555
uniprot id: A0A1W6BX72
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1121267:CCUN RS00930
gene id: 1121267:CCUN_RS00930
uniprot id: A0A1W6BUS5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS08595
gene id: 1121267:CCUN_RS08595
uniprot id: A0A1W6BYW7
names: Similarity
messages: Belongs to the Nth/MutY family.

1121267:CCUN RS02450
gene id: 1121267:CCUN_RS02450
uniprot id: W5ZRZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1121267:CCUN RS00305
gene id: 1121267:CCUN_RS00305
uniprot id: A0A1W6BUF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1121267:CCUN RS08220
gene id: 1121267:CCUN_RS08220
uniprot id: A0A1W6BYR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1121267:CCUN RS09375
gene id: 1121267:CCUN_RS09375
uniprot id: A0A1W6BZC6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1121267:CCUN RS00890
gene id: 1121267:CCUN_RS00890
uniprot id: A0A1W6BUR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1121267:CCUN RS09025
gene id: 1121267:CCUN_RS09025
uniprot id: A0A1W6BZ65
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1121267:CCUN RS03875
gene id: 1121267:CCUN_RS03875
uniprot id: A0A1W6BWB8
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1121267:CCUN RS01535
gene id: 1121267:CCUN_RS01535
uniprot id: A0A1W6BV50
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1121267:CCUN RS04405
gene id: 1121267:CCUN_RS04405
uniprot id: A0A1W6BWK4
names: Similarity
messages: Belongs to the aspartokinase family.

1121267:CCUN RS07505
gene id: 1121267:CCUN_RS07505
uniprot id: A0A1W6BYC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1121267:CCUN RS03615
gene id: 1121267:CCUN_RS03615
uniprot id: A0A1W6BW91
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS03675
gene id: 1121267:CCUN_RS03675
uniprot id: A0A1W6BWA9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1121267:CCUN RS06380
gene id: 1121267:CCUN_RS06380
uniprot id: A0A1W6BXN3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1121267:CCUN RS07770
gene id: 1121267:CCUN_RS07770
uniprot id: A0A1W6BYG6
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

1121267:CCUN RS00480
gene id: 1121267:CCUN_RS00480
uniprot id: A0A1W6BUL3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1121267:CCUN RS01885
gene id: 1121267:CCUN_RS01885
uniprot id: A0A1W6BVB7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1121267:CCUN RS01905
gene id: 1121267:CCUN_RS01905
uniprot id: A0A1W6BVA5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1121267:CCUN RS01500
gene id: 1121267:CCUN_RS01500
uniprot id: A0A1W6BV39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1121267:CCUN RS08525
gene id: 1121267:CCUN_RS08525
uniprot id: A0A1W6BYZ1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1121267:CCUN RS02810
gene id: 1121267:CCUN_RS02810
uniprot id: A0A1W6BVR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121267:CCUN RS01030
gene id: 1121267:CCUN_RS01030
uniprot id: A0A1W6BUU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1121267:CCUN RS08355
gene id: 1121267:CCUN_RS08355
uniprot id: A0A1W6BYV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1121267:CCUN RS01670
gene id: 1121267:CCUN_RS01670
uniprot id: A0A1W6BV55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1121267:CCUN RS04455
gene id: 1121267:CCUN_RS04455
uniprot id: A0A1W6BWP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1121267:CCUN RS09145
gene id: 1121267:CCUN_RS09145
uniprot id: A0A1W6BZB3
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1121267:CCUN RS04065
gene id: 1121267:CCUN_RS04065
uniprot id: A0A1W6BWE0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS03065
gene id: 1121267:CCUN_RS03065
uniprot id: A0A1W6BVV6
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1121267:CCUN RS03650
gene id: 1121267:CCUN_RS03650
uniprot id: A0A1W6BW74
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS06830
gene id: 1121267:CCUN_RS06830
uniprot id: A0A1W6BXZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1121267:CCUN RS02640
gene id: 1121267:CCUN_RS02640
uniprot id: A0A1W6BVP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1121267:CCUN RS03425
gene id: 1121267:CCUN_RS03425
uniprot id: A0A1W6BW20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1121267:CCUN RS00870
gene id: 1121267:CCUN_RS00870
uniprot id: A0A1W6BUR1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1121267:CCUN RS05640
gene id: 1121267:CCUN_RS05640
uniprot id: A0A1W6BXB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1121267:CCUN RS03190
gene id: 1121267:CCUN_RS03190
uniprot id: A0A1W6BW13
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1121267:CCUN RS06740
gene id: 1121267:CCUN_RS06740
uniprot id: A0A1W6BXY2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1121267:CCUN RS05120
gene id: 1121267:CCUN_RS05120
uniprot id: A0A1W6BWY6
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1121267:CCUN RS00980
gene id: 1121267:CCUN_RS00980
uniprot id: A0A1W6BUT5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1121267:CCUN RS04590
gene id: 1121267:CCUN_RS04590
uniprot id: A0A1W6BWN6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1121267:CCUN RS07990
gene id: 1121267:CCUN_RS07990
uniprot id: A0A1W6BYP6
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1121267:CCUN RS06770
gene id: 1121267:CCUN_RS06770
uniprot id: A0A1W6BXZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1121267:CCUN RS04955
gene id: 1121267:CCUN_RS04955
uniprot id: A0A1W6BWZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1121267:CCUN RS05840
gene id: 1121267:CCUN_RS05840
uniprot id: A0A1W6BXC6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1121267:CCUN RS00125
gene id: 1121267:CCUN_RS00125
uniprot id: A0A1W6BUE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1121267:CCUN RS02600
gene id: 1121267:CCUN_RS02600
uniprot id: A0A1W6BVN2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121267:CCUN RS02930
gene id: 1121267:CCUN_RS02930
uniprot id: A0A1W6BVT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1121267:CCUN RS05695
gene id: 1121267:CCUN_RS05695
uniprot id: A0A1W6BXD1
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS04540
gene id: 1121267:CCUN_RS04540
uniprot id: A0A1W6BWR3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1121267:CCUN RS03230
gene id: 1121267:CCUN_RS03230
uniprot id: A0A1W6BVZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1121267:CCUN RS05360
gene id: 1121267:CCUN_RS05360
uniprot id: A0A1W6BX65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1121267:CCUN RS00130
gene id: 1121267:CCUN_RS00130
uniprot id: A0A1W6BUD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1121267:CCUN RS04300
gene id: 1121267:CCUN_RS04300
uniprot id: A0A1W6BWL2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1121267:CCUN RS01900
gene id: 1121267:CCUN_RS01900
uniprot id: A0A1W6BVC2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1121267:CCUN RS05690
gene id: 1121267:CCUN_RS05690
uniprot id: A0A1W6BXC4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1121267:CCUN RS03215
gene id: 1121267:CCUN_RS03215
uniprot id: A0A1W6BVX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1121267:CCUN RS03965
gene id: 1121267:CCUN_RS03965
uniprot id: A0A1W6BWB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1121267:CCUN RS00155
gene id: 1121267:CCUN_RS00155
uniprot id: A0A1W6BUC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1121267:CCUN RS05570
gene id: 1121267:CCUN_RS05570
uniprot id: A0A1W6BX71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1121267:CCUN RS07960
gene id: 1121267:CCUN_RS07960
uniprot id: A0A1W6BYJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1121267:CCUN RS04580
gene id: 1121267:CCUN_RS04580
uniprot id: A0A1W6BWR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1121267:CCUN RS04835
gene id: 1121267:CCUN_RS04835
uniprot id: A0A1W6BWW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Cell inner membrane
messages: Homopentamer. In the absence of Mg(2+), interactions between subunits are weakened, and dimers, trimers and tetramers can be observed in vitro.
messages: Mediates influx of magnesium ions.
messages: Membrane

1121267:CCUN RS03195
gene id: 1121267:CCUN_RS03195
uniprot id: A0A1W6BVZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1121267:CCUN RS06435
gene id: 1121267:CCUN_RS06435
uniprot id: A0A1W6BXP9
names: Similarity
messages: Belongs to the cytochrome c-552 family.

1121267:CCUN RS09215
gene id: 1121267:CCUN_RS09215
uniprot id: A0A1W6BZ90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1121267:CCUN RS02960
gene id: 1121267:CCUN_RS02960
uniprot id: A0A1W6BVZ2
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS04855
gene id: 1121267:CCUN_RS04855
uniprot id: A0A1W6BWW9
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1121267:CCUN RS01940
gene id: 1121267:CCUN_RS01940
uniprot id: A0A1W6BVC9
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS07200
gene id: 1121267:CCUN_RS07200
uniprot id: A0A1W6BY61
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1121267:CCUN RS09000
gene id: 1121267:CCUN_RS09000
uniprot id: A0A1W6BZ46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1121267:CCUN RS03265
gene id: 1121267:CCUN_RS03265
uniprot id: A0A1W6BVZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1121267:CCUN RS00825
gene id: 1121267:CCUN_RS00825
uniprot id: A0A1W6BUS6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1121267:CCUN RS08095
gene id: 1121267:CCUN_RS08095
uniprot id: A0A1W6BYQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1121267:CCUN RS04310
gene id: 1121267:CCUN_RS04310
uniprot id: A0A1W6BWP4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1121267:CCUN RS02995
gene id: 1121267:CCUN_RS02995
uniprot id: A0A1W6BVW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1121267:CCUN RS05970
gene id: 1121267:CCUN_RS05970
uniprot id: A0A1W6BXI2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1121267:CCUN RS04510
gene id: 1121267:CCUN_RS04510
uniprot id: A0A1W6BWM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

1121267:CCUN RS06755
gene id: 1121267:CCUN_RS06755
uniprot id: A0A1W6BXZ5
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

1121267:CCUN RS03755
gene id: 1121267:CCUN_RS03755
uniprot id: A0A1W6BWC6
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1121267:CCUN RS03815
gene id: 1121267:CCUN_RS03815
uniprot id: A0A1W6BWE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1121267:CCUN RS04425
gene id: 1121267:CCUN_RS04425
uniprot id: A0A1W6BWK5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS02400
gene id: 1121267:CCUN_RS02400
uniprot id: A0A1W6BVK4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1121267:CCUN RS08670
gene id: 1121267:CCUN_RS08670
uniprot id: A0A1W6BZ08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1121267:CCUN RS02935
gene id: 1121267:CCUN_RS02935
uniprot id: A0A1W6BVY0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1121267:CCUN RS09200
gene id: 1121267:CCUN_RS09200
uniprot id: A0A1W6BZC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1121267:CCUN RS00060
gene id: 1121267:CCUN_RS00060
uniprot id: A0A1W6BUE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1121267:CCUN RS01740
gene id: 1121267:CCUN_RS01740
uniprot id: A0A1W6BV86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1121267:CCUN RS07515
gene id: 1121267:CCUN_RS07515
uniprot id: A0A1W6BYH8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1121267:CCUN RS07175
gene id: 1121267:CCUN_RS07175
uniprot id: A0A1W6BY59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1121267:CCUN RS04730
gene id: 1121267:CCUN_RS04730
uniprot id: A0A1W6BWX7
names: Similarity
messages: Belongs to the AAA ATPase family.

1121267:CCUN RS02945
gene id: 1121267:CCUN_RS02945
uniprot id: A0A1W6BVV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1121267:CCUN RS02950
gene id: 1121267:CCUN_RS02950
uniprot id: A0A1W6BVT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1121267:CCUN RS01015
gene id: 1121267:CCUN_RS01015
uniprot id: A0A1W6BUU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1121267:CCUN RS03435
gene id: 1121267:CCUN_RS03435
uniprot id: A0A1W6BW65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1121267:CCUN RS02590
gene id: 1121267:CCUN_RS02590
uniprot id: A0A1W6BVP5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS05885
gene id: 1121267:CCUN_RS05885
uniprot id: A0A1W6BXG7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1121267:CCUN RS08980
gene id: 1121267:CCUN_RS08980
uniprot id: A0A1W6BZ54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1121267:CCUN RS06575
gene id: 1121267:CCUN_RS06575
uniprot id: A0A1W6BXT2
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS02550
gene id: 1121267:CCUN_RS02550
uniprot id: A0A1W6BVM2
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1121267:CCUN RS08290
gene id: 1121267:CCUN_RS08290
uniprot id: A0A1W6BYR5
names: Similarity
messages: Belongs to the XseB family.

1121267:CCUN RS08085
gene id: 1121267:CCUN_RS08085
uniprot id: A0A1W6BYT6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1121267:CCUN RS03700
gene id: 1121267:CCUN_RS03700
uniprot id: A0A1W6BW79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1121267:CCUN RS06610
gene id: 1121267:CCUN_RS06610
uniprot id: A0A1W6BXZ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.

1121267:CCUN RS05900
gene id: 1121267:CCUN_RS05900
uniprot id: A0A1W6BXG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1121267:CCUN RS00900
gene id: 1121267:CCUN_RS00900
uniprot id: A0A1W6BUT0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1121267:CCUN RS02430
gene id: 1121267:CCUN_RS02430
uniprot id: A0A1W6BVL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

1121267:CCUN RS04365
gene id: 1121267:CCUN_RS04365
uniprot id: A0A1W6BWL9
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1121267:CCUN RS05540
gene id: 1121267:CCUN_RS05540
uniprot id: A0A1W6BX70
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1121267:CCUN RS04715
gene id: 1121267:CCUN_RS04715
uniprot id: A0A1W6BWV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1121267:CCUN RS04520
gene id: 1121267:CCUN_RS04520
uniprot id: A0A1W6BWQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1121267:CCUN RS04685
gene id: 1121267:CCUN_RS04685
uniprot id: A0A1W6BWT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1121267:CCUN RS08300
gene id: 1121267:CCUN_RS08300
uniprot id: A0A1W6BYT5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1121267:CCUN RS05935
gene id: 1121267:CCUN_RS05935
uniprot id: A0A1W6BXI1
names: Similarity
messages: Belongs to the peptidase M24B family.

1121267:CCUN RS02050
gene id: 1121267:CCUN_RS02050
uniprot id: A0A1W6BVE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1121267:CCUN RS02000
gene id: 1121267:CCUN_RS02000
uniprot id: A0A1W6BVD3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1121267:CCUN RS06655
gene id: 1121267:CCUN_RS06655
uniprot id: A0A1W6BXX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1121267:CCUN RS05390
gene id: 1121267:CCUN_RS05390
uniprot id: A0A1W6BX88
names: Similarity
messages: Belongs to the RutC family.

1121267:CCUN RS02045
gene id: 1121267:CCUN_RS02045
uniprot id: A0A1W6BVD5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1121267:CCUN RS05715
gene id: 1121267:CCUN_RS05715
uniprot id: A0A1W6BXA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1121267:CCUN RS04120
gene id: 1121267:CCUN_RS04120
uniprot id: A0A1W6BWL5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS00070
gene id: 1121267:CCUN_RS00070
uniprot id: A0A1W6BUB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1121267:CCUN RS04690
gene id: 1121267:CCUN_RS04690
uniprot id: A0A1W6BWQ3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1121267:CCUN RS02605
gene id: 1121267:CCUN_RS02605
uniprot id: A0A1W6BVT3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1121267:CCUN RS04340
gene id: 1121267:CCUN_RS04340
uniprot id: A0A1W6BWI7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1121267:CCUN RS07330
gene id: 1121267:CCUN_RS07330
uniprot id: A0A1W6BY99
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1121267:CCUN RS00470
gene id: 1121267:CCUN_RS00470
uniprot id: A0A1W6BUJ7
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1121267:CCUN RS03805
gene id: 1121267:CCUN_RS03805
uniprot id: A0A1W6BWD5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1121267:CCUN RS06450
gene id: 1121267:CCUN_RS06450
uniprot id: A0A1W6BXM5
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1121267:CCUN RS07980
gene id: 1121267:CCUN_RS07980
uniprot id: A0A1W6BYR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1121267:CCUN RS02440
gene id: 1121267:CCUN_RS02440
uniprot id: A0A1W6BVK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1121267:CCUN RS01755
gene id: 1121267:CCUN_RS01755
uniprot id: A0A1W6BV92
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1121267:CCUN RS00495
gene id: 1121267:CCUN_RS00495
uniprot id: A0A1W6BUM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1121267:CCUN RS05600
gene id: 1121267:CCUN_RS05600
uniprot id: A0A1W6BXA2
names: Similarity
messages: Belongs to the thioredoxin family.

1121267:CCUN RS00935
gene id: 1121267:CCUN_RS00935
uniprot id: A0A1W6BUS0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1121267:CCUN RS02680
gene id: 1121267:CCUN_RS02680
uniprot id: A0A1W6BVR1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1121267:CCUN RS05730
gene id: 1121267:CCUN_RS05730
uniprot id: A0A1W6BXD2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1121267:CCUN RS06745
gene id: 1121267:CCUN_RS06745
uniprot id: A0A1W6BXU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1121267:CCUN RS04165
gene id: 1121267:CCUN_RS04165
uniprot id: A0A1W6BWG0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1121267:CCUN RS00110
gene id: 1121267:CCUN_RS00110
uniprot id: A0A1W6BUF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1121267:CCUN RS06445
gene id: 1121267:CCUN_RS06445
uniprot id: A0A1W6BXS4
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1121267:CCUN RS08480
gene id: 1121267:CCUN_RS08480
uniprot id: A0A1W6BYV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1121267:CCUN RS04775
gene id: 1121267:CCUN_RS04775
uniprot id: A0A1W6BWS0
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
messages: Secreted

1121267:CCUN RS02435
gene id: 1121267:CCUN_RS02435
uniprot id: A0A1W6BVN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1121267:CCUN RS08835
gene id: 1121267:CCUN_RS08835
uniprot id: A0A1W6BZ73
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Homodimer.

1121267:CCUN RS07170
gene id: 1121267:CCUN_RS07170
uniprot id: A0A1W6BY95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1121267:CCUN RS04255
gene id: 1121267:CCUN_RS04255
uniprot id: A0A1W6BWH4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1121267:CCUN RS08985
gene id: 1121267:CCUN_RS08985
uniprot id: A0A1W6BZ53
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1121267:CCUN RS05270
gene id: 1121267:CCUN_RS05270
uniprot id: A0A1W6BX21
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1121267:CCUN RS04765
gene id: 1121267:CCUN_RS04765
uniprot id: A0A1W6BWW8
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1121267:CCUN RS02890
gene id: 1121267:CCUN_RS02890
uniprot id: A0A1W6BVW1
names: Similarity
messages: Belongs to the UPF0751 family.

1121267:CCUN RS00960
gene id: 1121267:CCUN_RS00960
uniprot id: A0A1W6BUT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1121267:CCUN RS09050
gene id: 1121267:CCUN_RS09050
uniprot id: A0A1W6BZ56
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1121267:CCUN RS02370
gene id: 1121267:CCUN_RS02370
uniprot id: A0A1W6BVL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1121267:CCUN RS02860
gene id: 1121267:CCUN_RS02860
uniprot id: A0A1W6BVW7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1121267:CCUN RS05680
gene id: 1121267:CCUN_RS05680
uniprot id: A0A1W6BXC2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1121267:CCUN RS07815
gene id: 1121267:CCUN_RS07815
uniprot id: A0A1W6BYN7
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1121267:CCUN RS01810
gene id: 1121267:CCUN_RS01810
uniprot id: A0A1W6BV85
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1121267:CCUN RS01830
gene id: 1121267:CCUN_RS01830
uniprot id: A0A1W6BV83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1121267:CCUN RS02545
gene id: 1121267:CCUN_RS02545
uniprot id: A0A1W6BVQ4
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1121267:CCUN RS07410
gene id: 1121267:CCUN_RS07410
uniprot id: A0A1W6BYF3
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1121267:CCUN RS00015
gene id: 1121267:CCUN_RS00015
uniprot id: A0A1W6BUC3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1121267:CCUN RS01610
gene id: 1121267:CCUN_RS01610
uniprot id: A0A1W6BV46
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1121267:CCUN RS06685
gene id: 1121267:CCUN_RS06685
uniprot id: A0A1W6BXX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1121267:CCUN RS03840
gene id: 1121267:CCUN_RS03840
uniprot id: A0A1W6BWB7
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

1121267:CCUN RS06500
gene id: 1121267:CCUN_RS06500
uniprot id: A0A1W6BXN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1121267:CCUN RS02060
gene id: 1121267:CCUN_RS02060
uniprot id: A0A1W6BVE7
names: Subcellular Location Annotation
messages: Mitochondrion

1121267:CCUN RS07220
gene id: 1121267:CCUN_RS07220
uniprot id: A0A1W6BYA5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1121267:CCUN RS04970
gene id: 1121267:CCUN_RS04970
uniprot id: A0A1W6BX04
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1121267:CCUN RS07995
gene id: 1121267:CCUN_RS07995
uniprot id: A0A1W6BYM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1121267:CCUN RS01585
gene id: 1121267:CCUN_RS01585
uniprot id: A0A1W6BV60
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1121267:CCUN RS08055
gene id: 1121267:CCUN_RS08055
uniprot id: A0A1W6BYM9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1121267:CCUN RS00050
gene id: 1121267:CCUN_RS00050
uniprot id: A0A1W6BUB2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1121267:CCUN RS00190
gene id: 1121267:CCUN_RS00190
uniprot id: A0A1W6BUG7
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1121267:CCUN RS02470
gene id: 1121267:CCUN_RS02470
uniprot id: A0A1W6BVN1
names: Similarity
messages: Belongs to the ParB family.

1121267:CCUN RS05720
gene id: 1121267:CCUN_RS05720
uniprot id: A0A1W6BXI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1121267:CCUN RS01120
gene id: 1121267:CCUN_RS01120
uniprot id: A0A1W6BUZ4
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1121267:CCUN RS07380
gene id: 1121267:CCUN_RS07380
uniprot id: A0A1W6BYA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1121267:CCUN RS07240
gene id: 1121267:CCUN_RS07240
uniprot id: A0A1W6BY57
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1121267:CCUN RS05955
gene id: 1121267:CCUN_RS05955
uniprot id: A0A1W6BXH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121267:CCUN RS00360
gene id: 1121267:CCUN_RS00360
uniprot id: A0A1W6BUH3
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1121267:CCUN RS04450
gene id: 1121267:CCUN_RS04450
uniprot id: A0A1W6BWQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1121267:CCUN RS08945
gene id: 1121267:CCUN_RS08945
uniprot id: A0A1W6BZA2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1121267:CCUN RS04525
gene id: 1121267:CCUN_RS04525
uniprot id: A0A1W6BWQ1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1121267:CCUN RS05685
gene id: 1121267:CCUN_RS05685
uniprot id: A0A1W6BX97
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1121267:CCUN RS01065
gene id: 1121267:CCUN_RS01065
uniprot id: A0A1W6BUV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1121267:CCUN RS09325
gene id: 1121267:CCUN_RS09325
uniprot id: A0A1W6BZB4
names: Similarity
messages: Belongs to the RecJ family.

1121267:CCUN RS08965
gene id: 1121267:CCUN_RS08965
uniprot id: A0A1W6BZ67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1121267:CCUN RS00555
gene id: 1121267:CCUN_RS00555
uniprot id: A0A1W6BUM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1121267:CCUN RS02730
gene id: 1121267:CCUN_RS02730
uniprot id: A0A1W6BVS6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1121267:CCUN RS00500
gene id: 1121267:CCUN_RS00500
uniprot id: A0A1W6BUK9
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS03050
gene id: 1121267:CCUN_RS03050
uniprot id: A0A1W6BVX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1121267:CCUN RS09310
gene id: 1121267:CCUN_RS09310
uniprot id: A0A1W6BZA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

1121267:CCUN RS02735
gene id: 1121267:CCUN_RS02735
uniprot id: A0A1W6BVS0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

1121267:CCUN RS03810
gene id: 1121267:CCUN_RS03810
uniprot id: A0A1W6BW88
names: Similarity
messages: Belongs to the UPF0763 family.

1121267:CCUN RS03490
gene id: 1121267:CCUN_RS03490
uniprot id: A0A1W6BW23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1121267:CCUN RS05760
gene id: 1121267:CCUN_RS05760
uniprot id: A0A1W6BXF3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1121267:CCUN RS04180
gene id: 1121267:CCUN_RS04180
uniprot id: A0A1W6BWI8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS09005
gene id: 1121267:CCUN_RS09005
uniprot id: A0A1W6BZ77
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS03340
gene id: 1121267:CCUN_RS03340
uniprot id: A0A1W6BW52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1121267:CCUN RS06640
gene id: 1121267:CCUN_RS06640
uniprot id: A0A1W6BXW1
names: Similarity
messages: Belongs to the nitroreductase family.

1121267:CCUN RS08925
gene id: 1121267:CCUN_RS08925
uniprot id: A0A1W6BZ42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1121267:CCUN RS06950
gene id: 1121267:CCUN_RS06950
uniprot id: A0A1W6BY22
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS08025
gene id: 1121267:CCUN_RS08025
uniprot id: A0A1W6BYM6
names: Similarity
messages: Belongs to the UPF0234 family.

1121267:CCUN RS03035
gene id: 1121267:CCUN_RS03035
uniprot id: A0A1W6BVW0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1121267:CCUN RS03185
gene id: 1121267:CCUN_RS03185
uniprot id: A0A1W6BW22
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1121267:CCUN RS07465
gene id: 1121267:CCUN_RS07465
uniprot id: A0A1W6BYG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1121267:CCUN RS07965
gene id: 1121267:CCUN_RS07965
uniprot id: A0A1W6BYL1
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS07125
gene id: 1121267:CCUN_RS07125
uniprot id: A0A1W6BY44
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1121267:CCUN RS03200
gene id: 1121267:CCUN_RS03200
uniprot id: A0A1W6BVY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1121267:CCUN RS05605
gene id: 1121267:CCUN_RS05605
uniprot id: A0A1W6BX82
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1121267:CCUN RS04355
gene id: 1121267:CCUN_RS04355
uniprot id: A0A1W6BWJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1121267:CCUN RS07275
gene id: 1121267:CCUN_RS07275
uniprot id: A0A1W6BY78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1121267:CCUN RS06815
gene id: 1121267:CCUN_RS06815
uniprot id: A0A1W6BXY7
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS07215
gene id: 1121267:CCUN_RS07215
uniprot id: A0A1W6BY69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1121267:CCUN RS02675
gene id: 1121267:CCUN_RS02675
uniprot id: A0A1W6BVR3
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1121267:CCUN RS02595
gene id: 1121267:CCUN_RS02595
uniprot id: A0A1W6BVS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1121267:CCUN RS06985
gene id: 1121267:CCUN_RS06985
uniprot id: A0A1W6BY25
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1121267:CCUN RS02940
gene id: 1121267:CCUN_RS02940
uniprot id: A0A1W6BVX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1121267:CCUN RS00405
gene id: 1121267:CCUN_RS00405
uniprot id: A0A1W6BUI5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1121267:CCUN RS06310
gene id: 1121267:CCUN_RS06310
uniprot id: A0A1W6BXP4
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS06850
gene id: 1121267:CCUN_RS06850
uniprot id: A0A1W6BY06
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS00005
gene id: 1121267:CCUN_RS00005
uniprot id: A0A1W6BU87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1121267:CCUN RS07385
gene id: 1121267:CCUN_RS07385
uniprot id: A0A1W6BY98
names: Similarity
messages: Belongs to the DprA/Smf family.

1121267:CCUN RS05890
gene id: 1121267:CCUN_RS05890
uniprot id: A0A1W6BXE0
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1121267:CCUN RS08705
gene id: 1121267:CCUN_RS08705
uniprot id: A0A1W6BZ02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1121267:CCUN RS03860
gene id: 1121267:CCUN_RS03860
uniprot id: A0A1W6BW97
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1121267:CCUN RS04275
gene id: 1121267:CCUN_RS04275
uniprot id: A0A1W6BWH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1121267:CCUN RS07190
gene id: 1121267:CCUN_RS07190
uniprot id: A0A1W6BY48
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS01135
gene id: 1121267:CCUN_RS01135
uniprot id: A0A1W6BUW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1121267:CCUN RS08435
gene id: 1121267:CCUN_RS08435
uniprot id: A0A1W6BYV4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS00950
gene id: 1121267:CCUN_RS00950
uniprot id: A0A1W6BUR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1121267:CCUN RS03395
gene id: 1121267:CCUN_RS03395
uniprot id: A0A1W6BW62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1121267:CCUN RS03670
gene id: 1121267:CCUN_RS03670
uniprot id: A0A1W6BW56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1121267:CCUN RS03430
gene id: 1121267:CCUN_RS03430
uniprot id: A0A1W6BW46
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1121267:CCUN RS04435
gene id: 1121267:CCUN_RS04435
uniprot id: A0A1W6BWN9
names: Similarity
messages: Belongs to the ribF family.

1121267:CCUN RS07765
gene id: 1121267:CCUN_RS07765
uniprot id: A0A1W6BYM7
names: Similarity
messages: Belongs to the TrbI/VirB10 family.

1121267:CCUN RS01195
gene id: 1121267:CCUN_RS01195
uniprot id: A0A1W6BUY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1121267:CCUN RS01090
gene id: 1121267:CCUN_RS01090
uniprot id: A0A1W6BUX8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121267:CCUN RS01925
gene id: 1121267:CCUN_RS01925
uniprot id: A0A1W6BVD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1121267:CCUN RS02965
gene id: 1121267:CCUN_RS02965
uniprot id: A0A1W6BVU4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1121267:CCUN RS06020
gene id: 1121267:CCUN_RS06020
uniprot id: A0A1W6BXJ6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1121267:CCUN RS04760
gene id: 1121267:CCUN_RS04760
uniprot id: A0A1W6BWS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1121267:CCUN RS03520
gene id: 1121267:CCUN_RS03520
uniprot id: A0A1W6BW57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS02630
gene id: 1121267:CCUN_RS02630
uniprot id: A0A1W6BVQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1121267:CCUN RS04145
gene id: 1121267:CCUN_RS04145
uniprot id: A0A1W6BWI1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1121267:CCUN RS04085
gene id: 1121267:CCUN_RS04085
uniprot id: A0A1W6BWJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1121267:CCUN RS05330
gene id: 1121267:CCUN_RS05330
uniprot id: A0A1W6BX58
names: Similarity
messages: Belongs to the SCO1/2 family.

1121267:CCUN RS08725
gene id: 1121267:CCUN_RS08725
uniprot id: A0A1W6BZ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1121267:CCUN RS00325
gene id: 1121267:CCUN_RS00325
uniprot id: A0A1W6BUG1
names: Similarity
messages: Belongs to the bacterial secretin family.

1121267:CCUN RS02670
gene id: 1121267:CCUN_RS02670
uniprot id: A0A1W6BVS7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1121267:CCUN RS07115
gene id: 1121267:CCUN_RS07115
uniprot id: A0A1W6BY49
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

1121267:CCUN RS04830
gene id: 1121267:CCUN_RS04830
uniprot id: A0A1W6BWW2
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1121267:CCUN RS08825
gene id: 1121267:CCUN_RS08825
uniprot id: A0A1W6BZ21
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1121267:CCUN RS02465
gene id: 1121267:CCUN_RS02465
uniprot id: A0A1W6BVM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase B chain family.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

1121267:CCUN RS02460
gene id: 1121267:CCUN_RS02460
uniprot id: A0A1W6BVM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1121267:CCUN RS06130
gene id: 1121267:CCUN_RS06130
uniprot id: A0A1W6BXM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1121267:CCUN RS00400
gene id: 1121267:CCUN_RS00400
uniprot id: A0A1W6BUI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1121267:CCUN RS01835
gene id: 1121267:CCUN_RS01835
uniprot id: A0A1W6BVB3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1121267:CCUN RS01050
gene id: 1121267:CCUN_RS01050
uniprot id: A0A1W6BUT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1121267:CCUN RS03470
gene id: 1121267:CCUN_RS03470
uniprot id: A0A1W6BW44
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1121267:CCUN RS04360
gene id: 1121267:CCUN_RS04360
uniprot id: A0A1W6BWQ4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1121267:CCUN RS05265
gene id: 1121267:CCUN_RS05265
uniprot id: A0A1W6BX42
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

1121267:CCUN RS07045
gene id: 1121267:CCUN_RS07045
uniprot id: A0A1W6BY29
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1121267:CCUN RS08520
gene id: 1121267:CCUN_RS08520
uniprot id: A0A1W6BYX9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

1121267:CCUN RS04075
gene id: 1121267:CCUN_RS04075
uniprot id: A0A1W6BWG8
names: Similarity
messages: Belongs to the threonine synthase family.

1121267:CCUN RS00560
gene id: 1121267:CCUN_RS00560
uniprot id: A0A1W6BUL1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1121267:CCUN RS00435
gene id: 1121267:CCUN_RS00435
uniprot id: A0A1W6BUJ1
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1121267:CCUN RS00445
gene id: 1121267:CCUN_RS00445
uniprot id: A0A1W6BUL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1121267:CCUN RS05510
gene id: 1121267:CCUN_RS05510
uniprot id: A0A1W6BXA9
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS07305
gene id: 1121267:CCUN_RS07305
uniprot id: A0A1W6BY63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1121267:CCUN RS09425
gene id: 1121267:CCUN_RS09425
uniprot id: A0A1W6BZD1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1121267:CCUN RS00095
gene id: 1121267:CCUN_RS00095
uniprot id: A0A1W6BUD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1121267:CCUN RS07740
gene id: 1121267:CCUN_RS07740
uniprot id: A0A1W6BYH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1121267:CCUN RS04380
gene id: 1121267:CCUN_RS04380
uniprot id: A0A1W6BWN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1121267:CCUN RS02750
gene id: 1121267:CCUN_RS02750
uniprot id: A0A1W6BVV2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1121267:CCUN RS05135
gene id: 1121267:CCUN_RS05135
uniprot id: A0A1W6BWY9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS04400
gene id: 1121267:CCUN_RS04400
uniprot id: A0A1W6BWN2
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1121267:CCUN RS06055
gene id: 1121267:CCUN_RS06055
uniprot id: A0A1W6BXJ1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1121267:CCUN RS04720
gene id: 1121267:CCUN_RS04720
uniprot id: A0A1W6BWU9
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

1121267:CCUN RS02745
gene id: 1121267:CCUN_RS02745
uniprot id: A0A1W6BVS5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1121267:CCUN RS00855
gene id: 1121267:CCUN_RS00855
uniprot id: A0A1W6BUT9
names: Similarity
messages: Belongs to the pyruvate kinase family.

1121267:CCUN RS03515
gene id: 1121267:CCUN_RS03515
uniprot id: A0A1W6BW77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS01440
gene id: 1121267:CCUN_RS01440
uniprot id: A0A1W6BV19
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1121267:CCUN RS07300
gene id: 1121267:CCUN_RS07300
uniprot id: A0A1W6BY77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1121267:CCUN RS05525
gene id: 1121267:CCUN_RS05525
uniprot id: A0A1W6BXE6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1121267:CCUN RS01240
gene id: 1121267:CCUN_RS01240
uniprot id: A0A1W6BUZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1121267:CCUN RS00355
gene id: 1121267:CCUN_RS00355
uniprot id: A0A1W6BUH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1121267:CCUN RS01505
gene id: 1121267:CCUN_RS01505
uniprot id: A0A1W6BV26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

1121267:CCUN RS06925
gene id: 1121267:CCUN_RS06925
uniprot id: A0A1W6BY05
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS03665
gene id: 1121267:CCUN_RS03665
uniprot id: A0A1W6BWA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1121267:CCUN RS05575
gene id: 1121267:CCUN_RS05575
uniprot id: A0A1W6BXG3
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1121267:CCUN RS00080
gene id: 1121267:CCUN_RS00080
uniprot id: A0A1W6BUC7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1121267:CCUN RS04150
gene id: 1121267:CCUN_RS04150
uniprot id: A0A1W6BWF2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1121267:CCUN RS01825
gene id: 1121267:CCUN_RS01825
uniprot id: A0A1W6BV98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1121267:CCUN RS00420
gene id: 1121267:CCUN_RS00420
uniprot id: A0A1W6BUI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1121267:CCUN RS04265
gene id: 1121267:CCUN_RS04265
uniprot id: A0A1W6BWK7
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1121267:CCUN RS07475
gene id: 1121267:CCUN_RS07475
uniprot id: A0A1W6BYE8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1121267:CCUN RS05335
gene id: 1121267:CCUN_RS05335
uniprot id: A0A1W6BX35
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1121267:CCUN RS02575
gene id: 1121267:CCUN_RS02575
uniprot id: A0A1W6BVP8
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS07280
gene id: 1121267:CCUN_RS07280
uniprot id: A0A1W6BY91
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1121267:CCUN RS02815
gene id: 1121267:CCUN_RS02815
uniprot id: A0A1W6BVX0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1121267:CCUN RS02625
gene id: 1121267:CCUN_RS02625
uniprot id: A0A1W6BVQ5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1121267:CCUN RS03795
gene id: 1121267:CCUN_RS03795
uniprot id: A0A1W6BW93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1121267:CCUN RS08090
gene id: 1121267:CCUN_RS08090
uniprot id: A0A1W6BYM3
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1121267:CCUN RS00765
gene id: 1121267:CCUN_RS00765
uniprot id: A0A1W6BUP5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1121267:CCUN RS01945
gene id: 1121267:CCUN_RS01945
uniprot id: A0A1W6BVB5
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS01745
gene id: 1121267:CCUN_RS01745
uniprot id: A0A1W6BV88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1121267:CCUN RS09300
gene id: 1121267:CCUN_RS09300
uniprot id: A0A1W6BZC0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1121267:CCUN RS04705
gene id: 1121267:CCUN_RS04705
uniprot id: A0A1W6BWU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1121267:CCUN RS03355
gene id: 1121267:CCUN_RS03355
uniprot id: A0A1W6BW10
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS07080
gene id: 1121267:CCUN_RS07080
uniprot id: A0A1W6BY45
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS05210
gene id: 1121267:CCUN_RS05210
uniprot id: A0A1W6BX33
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1121267:CCUN RS07480
gene id: 1121267:CCUN_RS07480
uniprot id: A0A1W6BYB8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1121267:CCUN RS03130
gene id: 1121267:CCUN_RS03130
uniprot id: A0A1W6BVZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1121267:CCUN RS02715
gene id: 1121267:CCUN_RS02715
uniprot id: A0A1W6BVR2
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS01205
gene id: 1121267:CCUN_RS01205
uniprot id: A0A1W6BUY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1121267:CCUN RS07510
gene id: 1121267:CCUN_RS07510
uniprot id: A0A1W6BYB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1121267:CCUN RS01625
gene id: 1121267:CCUN_RS01625
uniprot id: A0A1W6BV70
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1121267:CCUN RS04470
gene id: 1121267:CCUN_RS04470
uniprot id: A0A1W6BWP5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1121267:CCUN RS03080
gene id: 1121267:CCUN_RS03080
uniprot id: A0A1W6BVW4
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1121267:CCUN RS02980
gene id: 1121267:CCUN_RS02980
uniprot id: A0A1W6BVU6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1121267:CCUN RS06340
gene id: 1121267:CCUN_RS06340
uniprot id: A0A1W6BXQ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS02705
gene id: 1121267:CCUN_RS02705
uniprot id: A0A1W6BVV3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS01530
gene id: 1121267:CCUN_RS01530
uniprot id: A0A1W6BV73
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1121267:CCUN RS06775
gene id: 1121267:CCUN_RS06775
uniprot id: A0A1W6BXX6
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS08600
gene id: 1121267:CCUN_RS08600
uniprot id: A0A1W6BZ37
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

1121267:CCUN RS01115
gene id: 1121267:CCUN_RS01115
uniprot id: A0A1W6BUW0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS03630
gene id: 1121267:CCUN_RS03630
uniprot id: A0A1W6BW66
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1121267:CCUN RS03180
gene id: 1121267:CCUN_RS03180
uniprot id: A0A1W6BVX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1121267:CCUN RS06065
gene id: 1121267:CCUN_RS06065
uniprot id: A0A1W6BXJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1121267:CCUN RS02765
gene id: 1121267:CCUN_RS02765
uniprot id: A0A1W6BVS1
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS08145
gene id: 1121267:CCUN_RS08145
uniprot id: A0A1W6BYR9
names: Similarity
messages: Belongs to the TrpF family.

1121267:CCUN RS05515
gene id: 1121267:CCUN_RS05515
uniprot id: A0A1W6BX99
names: Similarity
messages: Belongs to the GARS family.

1121267:CCUN RS02620
gene id: 1121267:CCUN_RS02620
uniprot id: A0A1W6BVR4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1121267:CCUN RS02570
gene id: 1121267:CCUN_RS02570
uniprot id: A0A1W6BVQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1121267:CCUN RS02540
gene id: 1121267:CCUN_RS02540
uniprot id: A0A1W6BVN5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: The fumarate reductase enzyme complex is required for fumarate respiration. This subunit anchors the complex in the membrane and binds a diheme cytochrome b.

1121267:CCUN RS05255
gene id: 1121267:CCUN_RS05255
uniprot id: A0A1W6BX92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1121267:CCUN RS09335
gene id: 1121267:CCUN_RS09335
uniprot id: A0A1W6BZH8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS08545
gene id: 1121267:CCUN_RS08545
uniprot id: A0A1W6BYV6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1121267:CCUN RS07430
gene id: 1121267:CCUN_RS07430
uniprot id: A0A1W6BYB3
names: Similarity
messages: Belongs to the HupF/HypC family.

1121267:CCUN RS04010
gene id: 1121267:CCUN_RS04010
uniprot id: A0A1W6BWH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1121267:CCUN RS09250
gene id: 1121267:CCUN_RS09250
uniprot id: A0A1W6BZB0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1121267:CCUN RS00970
gene id: 1121267:CCUN_RS00970
uniprot id: A0A1W6BUV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1121267:CCUN RS05340
gene id: 1121267:CCUN_RS05340
uniprot id: A0A1W6BX76
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1121267:CCUN RS05225
gene id: 1121267:CCUN_RS05225
uniprot id: A0A1W6BX39
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1121267:CCUN RS03165
gene id: 1121267:CCUN_RS03165
uniprot id: A0A1W6BW27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1121267:CCUN RS08185
gene id: 1121267:CCUN_RS08185
uniprot id: A0A1W6BYV7
names: Similarity
messages: Belongs to the PrpD family.

1121267:CCUN RS08690
gene id: 1121267:CCUN_RS08690
uniprot id: A0A1W6BZ19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1121267:CCUN RS00055
gene id: 1121267:CCUN_RS00055
uniprot id: A0A1W6BUB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1121267:CCUN RS05645
gene id: 1121267:CCUN_RS05645
uniprot id: A0A1W6BXC0
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS07185
gene id: 1121267:CCUN_RS07185
uniprot id: A0A1W6BY62
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS00790
gene id: 1121267:CCUN_RS00790
uniprot id: A0A1W6BUR4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS03775
gene id: 1121267:CCUN_RS03775
uniprot id: A0A1W6BW96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS08950
gene id: 1121267:CCUN_RS08950
uniprot id: A0A1W6BZ39
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1121267:CCUN RS03485
gene id: 1121267:CCUN_RS03485
uniprot id: A0A1W6BW71
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1121267:CCUN RS05665
gene id: 1121267:CCUN_RS05665
uniprot id: A0A1W6BX91
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1121267:CCUN RS08315
gene id: 1121267:CCUN_RS08315
uniprot id: A0A1W6BYT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1121267:CCUN RS04575
gene id: 1121267:CCUN_RS04575
uniprot id: A0A1W6BWU8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS03375
gene id: 1121267:CCUN_RS03375
uniprot id: A0A1W6BW14
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS01855
gene id: 1121267:CCUN_RS01855
uniprot id: A0A1W6BVB1
names: Similarity
messages: Belongs to the citrate synthase family.

1121267:CCUN RS06820
gene id: 1121267:CCUN_RS06820
uniprot id: A0A1W6BY14
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1121267:CCUN RS08625
gene id: 1121267:CCUN_RS08625
uniprot id: A0A1W6BYY4
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS06790
gene id: 1121267:CCUN_RS06790
uniprot id: A0A1W6BXV0
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1121267:CCUN RS07775
gene id: 1121267:CCUN_RS07775
uniprot id: A0A1W6BYJ6
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS09020
gene id: 1121267:CCUN_RS09020
uniprot id: A0A1W6BZ89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1121267:CCUN RS05670
gene id: 1121267:CCUN_RS05670
uniprot id: A0A1W6BXI4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1121267:CCUN RS04800
gene id: 1121267:CCUN_RS04800
uniprot id: A0A1W6BWW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1121267:CCUN RS07895
gene id: 1121267:CCUN_RS07895
uniprot id: A0A1W6BYK3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1121267:CCUN RS05495
gene id: 1121267:CCUN_RS05495
uniprot id: A0A1W6BX83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell membrane

1121267:CCUN RS06960
gene id: 1121267:CCUN_RS06960
uniprot id: A0A1W6BY70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1121267:CCUN RS02740
gene id: 1121267:CCUN_RS02740
uniprot id: A0A1W6BVP1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1121267:CCUN RS00270
gene id: 1121267:CCUN_RS00270
uniprot id: A0A1W6BUE9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1121267:CCUN RS08005
gene id: 1121267:CCUN_RS08005
uniprot id: A0A1W6BYM1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1121267:CCUN RS06675
gene id: 1121267:CCUN_RS06675
uniprot id: A0A1W6BXX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1121267:CCUN RS09220
gene id: 1121267:CCUN_RS09220
uniprot id: A0A1W6BZ83
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1121267:CCUN RS08135
gene id: 1121267:CCUN_RS08135
uniprot id: A0A1W6BYU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1121267:CCUN RS00510
gene id: 1121267:CCUN_RS00510
uniprot id: A0A1W6BUK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1121267:CCUN RS00115
gene id: 1121267:CCUN_RS00115
uniprot id: A0A1W6BUB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1121267:CCUN RS05700
gene id: 1121267:CCUN_RS05700
uniprot id: A0A1W6BX98
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1121267:CCUN RS02700
gene id: 1121267:CCUN_RS02700
uniprot id: A0A1W6BVP6
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1121267:CCUN RS04035
gene id: 1121267:CCUN_RS04035
uniprot id: A0A1W6BWJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1121267:CCUN RS06265
gene id: 1121267:CCUN_RS06265
uniprot id: A0A1W6BXN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1121267:CCUN RS08990
gene id: 1121267:CCUN_RS08990
uniprot id: A0A1W6BZ45
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1121267:CCUN RS09290
gene id: 1121267:CCUN_RS09290
uniprot id: A0A1W6BZC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1121267:CCUN RS05195
gene id: 1121267:CCUN_RS05195
uniprot id: A0A1W6BX38
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.

1121267:CCUN RS06050
gene id: 1121267:CCUN_RS06050
uniprot id: A0A1W6BXJ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1121267:CCUN RS07440
gene id: 1121267:CCUN_RS07440
uniprot id: A0A1W6BYA8
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1121267:CCUN RS01775
gene id: 1121267:CCUN_RS01775
uniprot id: A0A1W6BV89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1121267:CCUN RS06145
gene id: 1121267:CCUN_RS06145
uniprot id: A0A1W6BXQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1121267:CCUN RS00820
gene id: 1121267:CCUN_RS00820
uniprot id: A0A1W6BUQ4
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS02025
gene id: 1121267:CCUN_RS02025
uniprot id: A0A1W6BVF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1121267:CCUN RS05630
gene id: 1121267:CCUN_RS05630
uniprot id: A0A1W6BXB2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1121267:CCUN RS04600
gene id: 1121267:CCUN_RS04600
uniprot id: A0A1W6BWS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121267:CCUN RS07075
gene id: 1121267:CCUN_RS07075
uniprot id: A0A1W6BY36
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1121267:CCUN RS00380
gene id: 1121267:CCUN_RS00380
uniprot id: A0A1W6BUJ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1121267:CCUN RS06935
gene id: 1121267:CCUN_RS06935
uniprot id: A0A1W6BY13
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS06875
gene id: 1121267:CCUN_RS06875
uniprot id: A0A1W6BXZ7
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1121267:CCUN RS05180
gene id: 1121267:CCUN_RS05180
uniprot id: A0A1W6BX26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1121267:CCUN RS08675
gene id: 1121267:CCUN_RS08675
uniprot id: A0A1W6BYZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1121267:CCUN RS09195
gene id: 1121267:CCUN_RS09195
uniprot id: A0A1W6BZ98
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1121267:CCUN RS02880
gene id: 1121267:CCUN_RS02880
uniprot id: A0A1W6BVS9
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1121267:CCUN RS04115
gene id: 1121267:CCUN_RS04115
uniprot id: A0A1W6BWF1
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS00295
gene id: 1121267:CCUN_RS00295
uniprot id: A0A1W6BUI6
names: Similarity
messages: Belongs to the class-I fumarase family.

1121267:CCUN RS00235
gene id: 1121267:CCUN_RS00235
uniprot id: A0A1W6BUF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1121267:CCUN RS09055
gene id: 1121267:CCUN_RS09055
uniprot id: A0A1W6BZ87
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1121267:CCUN RS05875
gene id: 1121267:CCUN_RS05875
uniprot id: A0A1W6BXC8
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1121267:CCUN RS02445
gene id: 1121267:CCUN_RS02445
uniprot id: A0A1W6BVQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1121267:CCUN RS10150
gene id: 1121267:CCUN_RS10150
uniprot id: A0A1W6BWE4
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS04605
gene id: 1121267:CCUN_RS04605
uniprot id: A0A1W6BWP8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1121267:CCUN RS01990
gene id: 1121267:CCUN_RS01990
uniprot id: A0A1W6BVD8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1121267:CCUN RS06945
gene id: 1121267:CCUN_RS06945
uniprot id: A0A1W6BY17
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1121267:CCUN RS03400
gene id: 1121267:CCUN_RS03400
uniprot id: A0A1W6BW30
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1121267:CCUN RS08465
gene id: 1121267:CCUN_RS08465
uniprot id: A0A1W6BYW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1121267:CCUN RS08485
gene id: 1121267:CCUN_RS08485
uniprot id: A0A1W6BYW6
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1121267:CCUN RS02615
gene id: 1121267:CCUN_RS02615
uniprot id: A0A1W6BVM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1121267:CCUN RS00925
gene id: 1121267:CCUN_RS00925
uniprot id: A0A1W6BUT3
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

1121267:CCUN RS01055
gene id: 1121267:CCUN_RS01055
uniprot id: A0A1W6BUW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1121267:CCUN RS03325
gene id: 1121267:CCUN_RS03325
uniprot id: A0A1W6BW45
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS01680
gene id: 1121267:CCUN_RS01680
uniprot id: A0A1W6BV75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Cell inner membrane
messages: Membrane

1121267:CCUN RS02780
gene id: 1121267:CCUN_RS02780
uniprot id: A0A1W6BVT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1121267:CCUN RS01020
gene id: 1121267:CCUN_RS01020
uniprot id: A0A1W6BUX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1121267:CCUN RS03780
gene id: 1121267:CCUN_RS03780
uniprot id: A0A1W6BWD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1121267:CCUN RS04805
gene id: 1121267:CCUN_RS04805
uniprot id: A0A1W6BWT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1121267:CCUN RS06880
gene id: 1121267:CCUN_RS06880
uniprot id: A0A1W6BY04
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1121267:CCUN RS02645
gene id: 1121267:CCUN_RS02645
uniprot id: A0A1W6BVU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1121267:CCUN RS06045
gene id: 1121267:CCUN_RS06045
uniprot id: A0A1W6BXN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

1121267:CCUN RS07485
gene id: 1121267:CCUN_RS07485
uniprot id: A0A1W6BYC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1121267:CCUN RS03855
gene id: 1121267:CCUN_RS03855
uniprot id: A0A1W6BWE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1121267:CCUN RS07460
gene id: 1121267:CCUN_RS07460
uniprot id: A0A1W6BY96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1121267:CCUN RS02775
gene id: 1121267:CCUN_RS02775
uniprot id: A0A1W6BVU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1121267:CCUN RS08905
gene id: 1121267:CCUN_RS08905
uniprot id: A0A1W6BZ43
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1121267:CCUN RS07425
gene id: 1121267:CCUN_RS07425
uniprot id: A0A1W6BYD8
names: Similarity
messages: Belongs to the HypD family.

1121267:CCUN RS08060
gene id: 1121267:CCUN_RS08060
uniprot id: A0A1W6BYP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1121267:CCUN RS06160
gene id: 1121267:CCUN_RS06160
uniprot id: A0A1W6BXJ2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1121267:CCUN RS05205
gene id: 1121267:CCUN_RS05205
uniprot id: A0A1W6BX80
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.

1121267:CCUN RS06760
gene id: 1121267:CCUN_RS06760
uniprot id: A0A1W6BY30
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1121267:CCUN RS08045
gene id: 1121267:CCUN_RS08045
uniprot id: A0A1W6BYQ2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1121267:CCUN RS02905
gene id: 1121267:CCUN_RS02905
uniprot id: A0A1W6BVV9
names: Similarity
messages: Belongs to the TrpC family.

1121267:CCUN RS08030
gene id: 1121267:CCUN_RS08030
uniprot id: A0A1W6BYL2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1121267:CCUN RS04915
gene id: 1121267:CCUN_RS04915
uniprot id: A0A1W6BWY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1121267:CCUN RS08440
gene id: 1121267:CCUN_RS08440
uniprot id: A0A1W6BYV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1121267:CCUN RS00770
gene id: 1121267:CCUN_RS00770
uniprot id: A0A1W6BUP0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1121267:CCUN RS00810
gene id: 1121267:CCUN_RS00810
uniprot id: A0A1W6BUR0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1121267:CCUN RS06440
gene id: 1121267:CCUN_RS06440
uniprot id: A0A1W6BXR8
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

1121267:CCUN RS06905
gene id: 1121267:CCUN_RS06905
uniprot id: A0A1W6BXW9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1121267:CCUN RS05115
gene id: 1121267:CCUN_RS05115
uniprot id: A0A1W6BX08
names: Similarity
messages: Belongs to the YggT family.

1121267:CCUN RS00815
gene id: 1121267:CCUN_RS00815
uniprot id: A0A1W6BUQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Homodimer.

1121267:CCUN RS05615
gene id: 1121267:CCUN_RS05615
uniprot id: A0A1W6BXB5
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1121267:CCUN RS08320
gene id: 1121267:CCUN_RS08320
uniprot id: A0A1W6BYT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1121267:CCUN RS09275
gene id: 1121267:CCUN_RS09275
uniprot id: A0A1W6BZ93
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS06900
gene id: 1121267:CCUN_RS06900
uniprot id: A0A1W6BY12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1121267:CCUN RS08475
gene id: 1121267:CCUN_RS08475
uniprot id: A0A1W6BYY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1121267:CCUN RS02835
gene id: 1121267:CCUN_RS02835
uniprot id: A0A1W6BVV0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1121267:CCUN RS03305
gene id: 1121267:CCUN_RS03305
uniprot id: A0A1W6BW34
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gmhB family.
messages: Cytoplasm
messages: Monomer.

1121267:CCUN RS04790
gene id: 1121267:CCUN_RS04790
uniprot id: A0A1W6BWV6
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Periplasm

1121267:CCUN RS08470
gene id: 1121267:CCUN_RS08470
uniprot id: A0A1W6BYW4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1121267:CCUN RS06730
gene id: 1121267:CCUN_RS06730
uniprot id: A0A1W6BXW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1121267:CCUN RS05975
gene id: 1121267:CCUN_RS05975
uniprot id: A0A1W6BXE5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1121267:CCUN RS07025
gene id: 1121267:CCUN_RS07025
uniprot id: A0A1W6BY19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1121267:CCUN RS04250
gene id: 1121267:CCUN_RS04250
uniprot id: A0A1W6BWK2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1121267:CCUN RS04930
gene id: 1121267:CCUN_RS04930
uniprot id: A0A1W6BWY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS07345
gene id: 1121267:CCUN_RS07345
uniprot id: A0A1W6BY88
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1121267:CCUN RS04960
gene id: 1121267:CCUN_RS04960
uniprot id: A0A1W6BWV9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS05145
gene id: 1121267:CCUN_RS05145
uniprot id: A0A1W6BX28
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS02455
gene id: 1121267:CCUN_RS02455
uniprot id: A0A1W6BVJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1121267:CCUN RS00220
gene id: 1121267:CCUN_RS00220
uniprot id: A0A1W6BUE0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS01815
gene id: 1121267:CCUN_RS01815
uniprot id: A0A1W6BV87
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1121267:CCUN RS04560
gene id: 1121267:CCUN_RS04560
uniprot id: A0A1W6BWR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1121267:CCUN RS03295
gene id: 1121267:CCUN_RS03295
uniprot id: A0A1W6BW01
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1121267:CCUN RS06765
gene id: 1121267:CCUN_RS06765
uniprot id: A0A1W6BXX7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1121267:CCUN RS03205
gene id: 1121267:CCUN_RS03205
uniprot id: A0A1W6BW08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1121267:CCUN RS07205
gene id: 1121267:CCUN_RS07205
uniprot id: A0A1W6BY42
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1121267:CCUN RS08255
gene id: 1121267:CCUN_RS08255
uniprot id: A0A1W6BYS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1121267:CCUN RS04505
gene id: 1121267:CCUN_RS04505
uniprot id: A0A1W6BWQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1121267:CCUN RS03600
gene id: 1121267:CCUN_RS03600
uniprot id: A0A1W6BW68
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS02485
gene id: 1121267:CCUN_RS02485
uniprot id: A0A1W6BVQ0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1121267:CCUN RS05960
gene id: 1121267:CCUN_RS05960
uniprot id: A0A1W6BXF2
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

1121267:CCUN RS04210
gene id: 1121267:CCUN_RS04210
uniprot id: A0A1W6BWJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1121267:CCUN RS06665
gene id: 1121267:CCUN_RS06665
uniprot id: A0A1W6BY09
names: Similarity
messages: Belongs to the sigma-54 factor family.

1121267:CCUN RS06845
gene id: 1121267:CCUN_RS06845
uniprot id: A0A1W6BY08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1121267:CCUN RS00755
gene id: 1121267:CCUN_RS00755
uniprot id: A0A1W6BUR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1121267:CCUN RS01685
gene id: 1121267:CCUN_RS01685
uniprot id: A0A1W6BV77
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1121267:CCUN RS02770
gene id: 1121267:CCUN_RS02770
uniprot id: A0A1W6BVQ2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1121267:CCUN RS04325
gene id: 1121267:CCUN_RS04325
uniprot id: A0A1W6BWI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1121267:CCUN RS01140
gene id: 1121267:CCUN_RS01140
uniprot id: A0A1W6BUZ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1121267:CCUN RS02410
gene id: 1121267:CCUN_RS02410
uniprot id: A0A1W6BVL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

1121267:CCUN RS04185
gene id: 1121267:CCUN_RS04185
uniprot id: A0A1W6BWG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1121267:CCUN RS04530
gene id: 1121267:CCUN_RS04530
uniprot id: A0A1W6BWM5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1121267:CCUN RS09255
gene id: 1121267:CCUN_RS09255
uniprot id: A0A1W6BZD6
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1121267:CCUN RS07470
gene id: 1121267:CCUN_RS07470
uniprot id: A0A1W6BYB5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1121267:CCUN RS09115
gene id: 1121267:CCUN_RS09115
uniprot id: A0A1W6BZ60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1121267:CCUN RS09230
gene id: 1121267:CCUN_RS09230
uniprot id: A0A1W6BZ85
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1121267:CCUN RS06315
gene id: 1121267:CCUN_RS06315
uniprot id: A0A1W6BXP8
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS09225
gene id: 1121267:CCUN_RS09225
uniprot id: A0A1W6BZF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1121267:CCUN RS01565
gene id: 1121267:CCUN_RS01565
uniprot id: A0A1W6BV62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1121267:CCUN RS03695
gene id: 1121267:CCUN_RS03695
uniprot id: A0A1W6BW80
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1121267:CCUN RS03635
gene id: 1121267:CCUN_RS03635
uniprot id: A0A1W6BW61
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1121267:CCUN RS06990
gene id: 1121267:CCUN_RS06990
uniprot id: A0A1W6BXZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1121267:CCUN RS08305
gene id: 1121267:CCUN_RS08305
uniprot id: A0A1W6BYT3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1121267:CCUN RS05535
gene id: 1121267:CCUN_RS05535
uniprot id: A0A1W6BX93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1121267:CCUN RS00145
gene id: 1121267:CCUN_RS00145
uniprot id: A0A1W6BUE4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1121267:CCUN RS08325
gene id: 1121267:CCUN_RS08325
uniprot id: A0A1W6BYR8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1121267:CCUN RS08755
gene id: 1121267:CCUN_RS08755
uniprot id: A0A1W6BZ13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1121267:CCUN RS08500
gene id: 1121267:CCUN_RS08500
uniprot id: A0A1W6BZ18
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1121267:CCUN RS00240
gene id: 1121267:CCUN_RS00240
uniprot id: A0A1W6BUH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1121267:CCUN RS08885
gene id: 1121267:CCUN_RS08885
uniprot id: A0A1W6BZ30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1121267:CCUN RS09245
gene id: 1121267:CCUN_RS09245
uniprot id: A0A1W6BZ79
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1121267:CCUN RS00260
gene id: 1121267:CCUN_RS00260
uniprot id: A0A1W6BUE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Dps family.
messages: Cytoplasm

1121267:CCUN RS05675
gene id: 1121267:CCUN_RS05675
uniprot id: A0A1W6BXC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1121267:CCUN RS04595
gene id: 1121267:CCUN_RS04595
uniprot id: A0A1W6BWS9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1121267:CCUN RS09330
gene id: 1121267:CCUN_RS09330
uniprot id: A0A1W6BZA0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS02755
gene id: 1121267:CCUN_RS02755
uniprot id: A0A1W6BVQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1121267:CCUN RS01930
gene id: 1121267:CCUN_RS01930
uniprot id: A0A1W6BVD0
names: Similarity
messages: Belongs to the UPF0423 family.

1121267:CCUN RS08140
gene id: 1121267:CCUN_RS08140
uniprot id: A0A1W6BYN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1121267:CCUN RS01265
gene id: 1121267:CCUN_RS01265
uniprot id: A0A1W6BV20
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

1121267:CCUN RS01570
gene id: 1121267:CCUN_RS01570
uniprot id: A0A1W6BV53
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1121267:CCUN RS00105
gene id: 1121267:CCUN_RS00105
uniprot id: A0A1W6BUB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1121267:CCUN RS06630
gene id: 1121267:CCUN_RS06630
uniprot id: A0A1W6BXU2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1121267:CCUN RS06000
gene id: 1121267:CCUN_RS06000
uniprot id: A0A1W6BXH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1121267:CCUN RS04030
gene id: 1121267:CCUN_RS04030
uniprot id: A0A1W6BWE1
names: Similarity
messages: Belongs to the peptidase M16 family.

1121267:CCUN RS08205
gene id: 1121267:CCUN_RS08205
uniprot id: A0A1W6BYR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS07940
gene id: 1121267:CCUN_RS07940
uniprot id: A0A1W6BYN4
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1121267:CCUN RS01495
gene id: 1121267:CCUN_RS01495
uniprot id: A0A1W6BV61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1121267:CCUN RS03450
gene id: 1121267:CCUN_RS03450
uniprot id: A0A1W6BW40
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1121267:CCUN RS01145
gene id: 1121267:CCUN_RS01145
uniprot id: A0A1W6BUW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1121267:CCUN RS07355
gene id: 1121267:CCUN_RS07355
uniprot id: A0A1W6BY81
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS04280
gene id: 1121267:CCUN_RS04280
uniprot id: A0A1W6BWL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

1121267:CCUN RS08550
gene id: 1121267:CCUN_RS08550
uniprot id: A0A1W6BZ29
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1121267:CCUN RS01060
gene id: 1121267:CCUN_RS01060
uniprot id: A0A1W6BUV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1121267:CCUN RS04335
gene id: 1121267:CCUN_RS04335
uniprot id: A0A1W6BWM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cytoplasm

1121267:CCUN RS00860
gene id: 1121267:CCUN_RS00860
uniprot id: A0A1W6BUS1
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1121267:CCUN RS06395
gene id: 1121267:CCUN_RS06395
uniprot id: A0A1W6BXL6
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS02565
gene id: 1121267:CCUN_RS02565
uniprot id: A0A1W6BVL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Secreted

1121267:CCUN RS01820
gene id: 1121267:CCUN_RS01820
uniprot id: A0A1W6BVC1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Monomer. Binds crRNA and tracrRNA.

1121267:CCUN RS00100
gene id: 1121267:CCUN_RS00100
uniprot id: A0A1W6BUB7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1121267:CCUN RS08565
gene id: 1121267:CCUN_RS08565
uniprot id: A0A1W6BYX4
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS00010
gene id: 1121267:CCUN_RS00010
uniprot id: A0A1W6BUA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1121267:CCUN RS05650
gene id: 1121267:CCUN_RS05650
uniprot id: A0A1W6BX90
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS03820
gene id: 1121267:CCUN_RS03820
uniprot id: A0A1W6BWB3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1121267:CCUN RS01920
gene id: 1121267:CCUN_RS01920
uniprot id: A0A1W6BVB6
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1121267:CCUN RS05110
gene id: 1121267:CCUN_RS05110
uniprot id: A0A1W6BX11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1121267:CCUN RS06230
gene id: 1121267:CCUN_RS06230
uniprot id: A0A1W6BXI7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1121267:CCUN RS02330
gene id: 1121267:CCUN_RS02330
uniprot id: A0A1W6BVN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS01985
gene id: 1121267:CCUN_RS01985
uniprot id: A0A1W6BVF8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1121267:CCUN RS01595
gene id: 1121267:CCUN_RS01595
uniprot id: A0A1W6BV49
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1121267:CCUN RS03290
gene id: 1121267:CCUN_RS03290
uniprot id: A0A1W6BW16
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1121267:CCUN RS08720
gene id: 1121267:CCUN_RS08720
uniprot id: A0A1W6BYZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1121267:CCUN RS03580
gene id: 1121267:CCUN_RS03580
uniprot id: A0A1W6BW60
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS08860
gene id: 1121267:CCUN_RS08860
uniprot id: A0A1W6BZ44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1121267:CCUN RS00210
gene id: 1121267:CCUN_RS00210
uniprot id: A0A1W6BUG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1121267:CCUN RS03990
gene id: 1121267:CCUN_RS03990
uniprot id: A0A1W6BWG7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1121267:CCUN RS00460
gene id: 1121267:CCUN_RS00460
uniprot id: A0A1W6BUJ4
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1121267:CCUN RS03170
gene id: 1121267:CCUN_RS03170
uniprot id: A0A1W6BVZ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1121267:CCUN RS00370
gene id: 1121267:CCUN_RS00370
uniprot id: A0A1W6BUH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1121267:CCUN RS00135
gene id: 1121267:CCUN_RS00135
uniprot id: A0A1W6BUD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1121267:CCUN RS09010
gene id: 1121267:CCUN_RS09010
uniprot id: A0A1W6BZ49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1121267:CCUN RS05400
gene id: 1121267:CCUN_RS05400
uniprot id: A0A1W6BX44
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1121267:CCUN RS03530
gene id: 1121267:CCUN_RS03530
uniprot id: A0A1W6BW64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1121267:CCUN RS02695
gene id: 1121267:CCUN_RS02695
uniprot id: A0A1W6BVU2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1121267:CCUN RS00245
gene id: 1121267:CCUN_RS00245
uniprot id: A0A1W6BUG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS08175
gene id: 1121267:CCUN_RS08175
uniprot id: A0A1W6BYQ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS00465
gene id: 1121267:CCUN_RS00465
uniprot id: A0A1W6BUL6
names: Cofactor
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1121267:CCUN RS08335
gene id: 1121267:CCUN_RS08335
uniprot id: A0A1W6BYS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1121267:CCUN RS03135
gene id: 1121267:CCUN_RS03135
uniprot id: A0A1W6BW19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1121267:CCUN RS03140
gene id: 1121267:CCUN_RS03140
uniprot id: A0A1W6BVW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1121267:CCUN RS07055
gene id: 1121267:CCUN_RS07055
uniprot id: A0A1W6BY03
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1121267:CCUN RS01515
gene id: 1121267:CCUN_RS01515
uniprot id: A0A1W6BV44
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1121267:CCUN RS01210
gene id: 1121267:CCUN_RS01210
uniprot id: A0A1W6BUX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1121267:CCUN RS07890
gene id: 1121267:CCUN_RS07890
uniprot id: A0A1W6BYJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

1121267:CCUN RS00265
gene id: 1121267:CCUN_RS00265
uniprot id: A0A1W6BUH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1121267:CCUN RS00440
gene id: 1121267:CCUN_RS00440
uniprot id: A0A1W6BUJ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1121267:CCUN RS03370
gene id: 1121267:CCUN_RS03370
uniprot id: A0A1W6BW25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1121267:CCUN RS06280
gene id: 1121267:CCUN_RS06280
uniprot id: A0A1W6BXP5
names: Subcellular Location Annotation
messages: Membrane

1121267:CCUN RS08785
gene id: 1121267:CCUN_RS08785
uniprot id: A0A1W6BZ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121267:CCUN RS08930
gene id: 1121267:CCUN_RS08930
uniprot id: A0A1W6BZ47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1121267:CCUN RS01000
gene id: 1121267:CCUN_RS01000
uniprot id: A0A1W6BUS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1121267:CCUN RS03040
gene id: 1121267:CCUN_RS03040
uniprot id: A0A1W6BW05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

1121267:CCUN RS07395
gene id: 1121267:CCUN_RS07395
uniprot id: A0A1W6BYA3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1121267:CCUN RS04890
gene id: 1121267:CCUN_RS04890
uniprot id: A0A1W6BWU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerH subfamily.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1121267:CCUN RS02520
gene id: 1121267:CCUN_RS02520
uniprot id: A0A1W6BVN8
names: Similarity
messages: Belongs to the IMPACT family.

1121267:CCUN RS03955
gene id: 1121267:CCUN_RS03955
uniprot id: A0A1W6BWE3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1121267:CCUN RS02855
gene id: 1121267:CCUN_RS02855
uniprot id: A0A1W6BVU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1121267:CCUN RS05965
gene id: 1121267:CCUN_RS05965
uniprot id: A0A1W6BXH1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1121267:CCUN RS08430
gene id: 1121267:CCUN_RS08430
uniprot id: A0A1W6BYU6
names: Similarity
messages: Belongs to the DprA/Smf family.