1109412:AWC36 RS23160
gene id: 1109412:AWC36_RS23160
uniprot id: A0A0G4JVI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS18580
gene id: 1109412:AWC36_RS18580
uniprot id: A0A0G4JT27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1109412:AWC36 RS21435
gene id: 1109412:AWC36_RS21435
uniprot id: A0A250BJY2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1109412:AWC36 RS00080
gene id: 1109412:AWC36_RS00080
uniprot id: A0A250BLS1
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1109412:AWC36 RS00995
gene id: 1109412:AWC36_RS00995
uniprot id: A0A0G4JWH5
names: Function
names: Similarity
messages: Belongs to the bacterial-type ferredoxin family. FixX subfamily.
messages: Could be a 3Fe-4S cluster-containing protein.

1109412:AWC36 RS08280
gene id: 1109412:AWC36_RS08280
uniprot id: A0A0G4K1F5
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

1109412:AWC36 RS17560
gene id: 1109412:AWC36_RS17560
uniprot id: A0A0G4JSD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1109412:AWC36 RS22905
gene id: 1109412:AWC36_RS22905
uniprot id: A0A0G4JVZ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
messages: Homodimer.

1109412:AWC36 RS05850
gene id: 1109412:AWC36_RS05850
uniprot id: A0A250BBW4
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1109412:AWC36 RS06660
gene id: 1109412:AWC36_RS06660
uniprot id: A0A0G4JZZ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

1109412:AWC36 RS21755
gene id: 1109412:AWC36_RS21755
uniprot id: A0A0G4JV00
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1109412:AWC36 RS03920
gene id: 1109412:AWC36_RS03920
uniprot id: A0A0G4JY12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS08150
gene id: 1109412:AWC36_RS08150
uniprot id: A0A0G4K0V2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1109412:AWC36 RS12595
gene id: 1109412:AWC36_RS12595
uniprot id: A0A0G4JPZ4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1109412:AWC36 RS12405
gene id: 1109412:AWC36_RS12405
uniprot id: A0A0G4JPA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS10825
gene id: 1109412:AWC36_RS10825
uniprot id: A0A250BL41
names: Similarity
messages: Belongs to the UPF0423 family.

1109412:AWC36 RS21420
gene id: 1109412:AWC36_RS21420
uniprot id: A0A0G4JUR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1109412:AWC36 RS21450
gene id: 1109412:AWC36_RS21450
uniprot id: A0A250BJG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1109412:AWC36 RS08345
gene id: 1109412:AWC36_RS08345
uniprot id: A0A0G4K0N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1109412:AWC36 RS11225
gene id: 1109412:AWC36_RS11225
uniprot id: A0A0G4K385
names: Similarity
messages: Belongs to the peptidase S24 family.

1109412:AWC36 RS01890
gene id: 1109412:AWC36_RS01890
uniprot id: A0A0G4JWN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1109412:AWC36 RS12165
gene id: 1109412:AWC36_RS12165
uniprot id: A0A250BFU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.

1109412:AWC36 RS17940
gene id: 1109412:AWC36_RS17940
uniprot id: A0A0G4JSN3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1109412:AWC36 RS20815
gene id: 1109412:AWC36_RS20815
uniprot id: A0A0G4JUV8
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS04750
gene id: 1109412:AWC36_RS04750
uniprot id: A0A0G4JZ38
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

1109412:AWC36 RS08990
gene id: 1109412:AWC36_RS08990
uniprot id: A0A250BL66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-(acyl)-lipid IV(A) to form a Kdo(2)-lipid A.
messages: Cell inner membrane

1109412:AWC36 RS07790
gene id: 1109412:AWC36_RS07790
uniprot id: A0A0G4K0C2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS07245
gene id: 1109412:AWC36_RS07245
uniprot id: A0A0G4K0C3
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS18125
gene id: 1109412:AWC36_RS18125
uniprot id: A0A0G4JSP3
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1109412:AWC36 RS20770
gene id: 1109412:AWC36_RS20770
uniprot id: A0A0G4JUB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS05780
gene id: 1109412:AWC36_RS05780
uniprot id: A0A0G4JZ66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
messages: Cell membrane
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

1109412:AWC36 RS20640
gene id: 1109412:AWC36_RS20640
uniprot id: A0A0G4JU79
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1109412:AWC36 RS19340
gene id: 1109412:AWC36_RS19340
uniprot id: A0A0G4JU43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1109412:AWC36 RS00810
gene id: 1109412:AWC36_RS00810
uniprot id: A0A250B9I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RcsF family.
messages: Cell outer membrane
messages: Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects.

1109412:AWC36 RS08910
gene id: 1109412:AWC36_RS08910
uniprot id: A0A0G4K133
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS21240
gene id: 1109412:AWC36_RS21240
uniprot id: A0A0G4JUM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS12090
gene id: 1109412:AWC36_RS12090
uniprot id: A0A0G4JP42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1109412:AWC36 RS20860
gene id: 1109412:AWC36_RS20860
uniprot id: A0A0G4JUC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1109412:AWC36 RS17655
gene id: 1109412:AWC36_RS17655
uniprot id: A0A250BHR3
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1109412:AWC36 RS17230
gene id: 1109412:AWC36_RS17230
uniprot id: A0A0G4JS96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1109412:AWC36 RS08525
gene id: 1109412:AWC36_RS08525
uniprot id: A0A0G4K0V5
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS08710
gene id: 1109412:AWC36_RS08710
uniprot id: A0A0G4K1L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS18040
gene id: 1109412:AWC36_RS18040
uniprot id: A0A0G4JT86
names: Subcellular Location Annotation
messages: Cell inner membrane

1109412:AWC36 RS01675
gene id: 1109412:AWC36_RS01675
uniprot id: A0A0G4JWJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS15045
gene id: 1109412:AWC36_RS15045
uniprot id: A0A0G4JR15
names: Similarity
messages: Belongs to the GSP E family.

1109412:AWC36 RS01690
gene id: 1109412:AWC36_RS01690
uniprot id: A0A0G4JWN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1109412:AWC36 RS21430
gene id: 1109412:AWC36_RS21430
uniprot id: A0A0G4JUR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1109412:AWC36 RS20150
gene id: 1109412:AWC36_RS20150
uniprot id: A0A0G4JU01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1109412:AWC36 RS13715
gene id: 1109412:AWC36_RS13715
uniprot id: A0A0G4JQ12
names: Similarity
messages: Belongs to the UPF0325 family.

1109412:AWC36 RS08565
gene id: 1109412:AWC36_RS08565
uniprot id: A0A0G4K0S4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1109412:AWC36 RS07505
gene id: 1109412:AWC36_RS07505
uniprot id: A0A0G4K0G8
names: Similarity
messages: Belongs to the NifZ family.

1109412:AWC36 RS18790
gene id: 1109412:AWC36_RS18790
uniprot id: A0A0G4JTT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1109412:AWC36 RS22345
gene id: 1109412:AWC36_RS22345
uniprot id: A0A0G4JV60
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

1109412:AWC36 RS14600
gene id: 1109412:AWC36_RS14600
uniprot id: A0A0G4JQN0
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1109412:AWC36 RS18465
gene id: 1109412:AWC36_RS18465
uniprot id: A0A250BI62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein B family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS03585
gene id: 1109412:AWC36_RS03585
uniprot id: A0A0G4JY34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS23360
gene id: 1109412:AWC36_RS23360
uniprot id: A0A0G4JW93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

1109412:AWC36 RS03060
gene id: 1109412:AWC36_RS03060
uniprot id: A0A0G4JYB2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1109412:AWC36 RS18825
gene id: 1109412:AWC36_RS18825
uniprot id: A0A0G4JT53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1109412:AWC36 RS00520
gene id: 1109412:AWC36_RS00520
uniprot id: A0A0G4JW35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1109412:AWC36 RS20235
gene id: 1109412:AWC36_RS20235
uniprot id: A0A250BIV0
names: Similarity
messages: Belongs to the IMPACT family.

1109412:AWC36 RS17715
gene id: 1109412:AWC36_RS17715
uniprot id: A0A250BIN1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1109412:AWC36 RS06030
gene id: 1109412:AWC36_RS06030
uniprot id: A0A0G4JZF2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1109412:AWC36 RS21750
gene id: 1109412:AWC36_RS21750
uniprot id: A0A0G4JVK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdC family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

1109412:AWC36 RS17590
gene id: 1109412:AWC36_RS17590
uniprot id: A0A0G4JSD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1109412:AWC36 RS23175
gene id: 1109412:AWC36_RS23175
uniprot id: A0A0G4JVI6
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1109412:AWC36 RS09555
gene id: 1109412:AWC36_RS09555
uniprot id: A0A0G4K2D1
names: Similarity
messages: Belongs to the UPF0145 family.

1109412:AWC36 RS18290
gene id: 1109412:AWC36_RS18290
uniprot id: A0A0G4JSR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS15335
gene id: 1109412:AWC36_RS15335
uniprot id: A0A0G4JR39
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS04485
gene id: 1109412:AWC36_RS04485
uniprot id: A0A0G4JYP6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

1109412:AWC36 RS17155
gene id: 1109412:AWC36_RS17155
uniprot id: A0A0G4JS59
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1109412:AWC36 RS18850
gene id: 1109412:AWC36_RS18850
uniprot id: A0A0G4JT58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS20470
gene id: 1109412:AWC36_RS20470
uniprot id: A0A0G4JU48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.
messages: Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).
messages: Homodimer.

1109412:AWC36 RS18840
gene id: 1109412:AWC36_RS18840
uniprot id: A0A0G4JT60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.

1109412:AWC36 RS17535
gene id: 1109412:AWC36_RS17535
uniprot id: A0A0G4JSZ4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1109412:AWC36 RS21305
gene id: 1109412:AWC36_RS21305
uniprot id: A0A0G4JUP0
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1109412:AWC36 RS13060
gene id: 1109412:AWC36_RS13060
uniprot id: A0A0G4JPM2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1109412:AWC36 RS21715
gene id: 1109412:AWC36_RS21715
uniprot id: A0A0G4JUT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1109412:AWC36 RS18510
gene id: 1109412:AWC36_RS18510
uniprot id: A0A0G4JSW4
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS04360
gene id: 1109412:AWC36_RS04360
uniprot id: A0A0G4JYF9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1109412:AWC36 RS00785
gene id: 1109412:AWC36_RS00785
uniprot id: A0A0G4JWC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1109412:AWC36 RS00800
gene id: 1109412:AWC36_RS00800
uniprot id: A0A0G4JW96
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1109412:AWC36 RS14545
gene id: 1109412:AWC36_RS14545
uniprot id: A0A0G4JQL9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1109412:AWC36 RS13275
gene id: 1109412:AWC36_RS13275
uniprot id: A0A0G4JQ80
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1109412:AWC36 RS05585
gene id: 1109412:AWC36_RS05585
uniprot id: A0A0G4JZW1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1109412:AWC36 RS09010
gene id: 1109412:AWC36_RS09010
uniprot id: A0A0G4K1W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS03270
gene id: 1109412:AWC36_RS03270
uniprot id: A0A0G4JXT2
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1109412:AWC36 RS23610
gene id: 1109412:AWC36_RS23610
uniprot id: A0A0G4JVU3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1109412:AWC36 RS17060
gene id: 1109412:AWC36_RS17060
uniprot id: A0A0G4JS42
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1109412:AWC36 RS09200
gene id: 1109412:AWC36_RS09200
uniprot id: A0A0G4K1A3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1109412:AWC36 RS13070
gene id: 1109412:AWC36_RS13070
uniprot id: A0A0G4JPM8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1109412:AWC36 RS21460
gene id: 1109412:AWC36_RS21460
uniprot id: A0A0G4JVD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1109412:AWC36 RS20400
gene id: 1109412:AWC36_RS20400
uniprot id: A0A0G4JUM3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1109412:AWC36 RS17745
gene id: 1109412:AWC36_RS17745
uniprot id: A0A0G4JSG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1109412:AWC36 RS14410
gene id: 1109412:AWC36_RS14410
uniprot id: A0A0G4JQJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1109412:AWC36 RS14145
gene id: 1109412:AWC36_RS14145
uniprot id: A0A0G4JQE1
names: Subcellular Location Annotation
messages: Cell inner membrane

1109412:AWC36 RS17285
gene id: 1109412:AWC36_RS17285
uniprot id: A0A250BHW2
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1109412:AWC36 RS20350
gene id: 1109412:AWC36_RS20350
uniprot id: A0A0G4JUK8
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1109412:AWC36 RS15940
gene id: 1109412:AWC36_RS15940
uniprot id: A0A0G4JRF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS20895
gene id: 1109412:AWC36_RS20895
uniprot id: A0A0G4JUF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1109412:AWC36 RS01020
gene id: 1109412:AWC36_RS01020
uniprot id: A0A0G4JWI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

1109412:AWC36 RS17270
gene id: 1109412:AWC36_RS17270
uniprot id: A0A0G4JS74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1109412:AWC36 RS14775
gene id: 1109412:AWC36_RS14775
uniprot id: A0A0G4JRE3
names: Similarity
messages: Belongs to the CdaR family.

1109412:AWC36 RS21675
gene id: 1109412:AWC36_RS21675
uniprot id: A0A0G4JUV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the rhamnose mutarotase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the anomeric conversion of L-rhamnose.

1109412:AWC36 RS22815
gene id: 1109412:AWC36_RS22815
uniprot id: A0A0G4JVX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1109412:AWC36 RS07680
gene id: 1109412:AWC36_RS07680
uniprot id: A0A0G4K096
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1109412:AWC36 RS09530
gene id: 1109412:AWC36_RS09530
uniprot id: A0A250BDV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1109412:AWC36 RS02760
gene id: 1109412:AWC36_RS02760
uniprot id: A0A0G4JXH8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS13950
gene id: 1109412:AWC36_RS13950
uniprot id: A0A0G4JQ82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
messages: Monomer.

1109412:AWC36 RS12655
gene id: 1109412:AWC36_RS12655
uniprot id: A0A250BFA7
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1109412:AWC36 RS06645
gene id: 1109412:AWC36_RS06645
uniprot id: A0A250BC93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C40 family.
messages: Nucleus

1109412:AWC36 RS11095
gene id: 1109412:AWC36_RS11095
uniprot id: A0A0G4K2I5
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

1109412:AWC36 RS17335
gene id: 1109412:AWC36_RS17335
uniprot id: A0A0G4JSB8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1109412:AWC36 RS15810
gene id: 1109412:AWC36_RS15810
uniprot id: A0A0G4JRC3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1109412:AWC36 RS15095
gene id: 1109412:AWC36_RS15095
uniprot id: A0A0G4JR27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1109412:AWC36 RS20205
gene id: 1109412:AWC36_RS20205
uniprot id: A0A0G4JTX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1109412:AWC36 RS20485
gene id: 1109412:AWC36_RS20485
uniprot id: A0A0G4JU85
names: Function
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate.

1109412:AWC36 RS21410
gene id: 1109412:AWC36_RS21410
uniprot id: A0A0G4JVD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1109412:AWC36 RS23230
gene id: 1109412:AWC36_RS23230
uniprot id: A0A0G4JVH2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1109412:AWC36 RS17040
gene id: 1109412:AWC36_RS17040
uniprot id: A0A0G4JS37
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1109412:AWC36 RS00965
gene id: 1109412:AWC36_RS00965
uniprot id: A0A0G4JWE6
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons.

1109412:AWC36 RS18535
gene id: 1109412:AWC36_RS18535
uniprot id: A0A0G4JSY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1109412:AWC36 RS18530
gene id: 1109412:AWC36_RS18530
uniprot id: A0A250BI71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1109412:AWC36 RS15365
gene id: 1109412:AWC36_RS15365
uniprot id: A0A0G4JR77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1109412:AWC36 RS02650
gene id: 1109412:AWC36_RS02650
uniprot id: A0A0G4JXZ8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1109412:AWC36 RS07875
gene id: 1109412:AWC36_RS07875
uniprot id: A0A0G4K190
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm

1109412:AWC36 RS11690
gene id: 1109412:AWC36_RS11690
uniprot id: A0A0G4K2Z3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1109412:AWC36 RS06960
gene id: 1109412:AWC36_RS06960
uniprot id: A0A0G4K0K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS21535
gene id: 1109412:AWC36_RS21535
uniprot id: A0A250BJW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1109412:AWC36 RS03085
gene id: 1109412:AWC36_RS03085
uniprot id: A0A0G4JXM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

1109412:AWC36 RS21045
gene id: 1109412:AWC36_RS21045
uniprot id: A0A0G4JUI6
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS13360
gene id: 1109412:AWC36_RS13360
uniprot id: A0A0G4JPX6
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1109412:AWC36 RS17145
gene id: 1109412:AWC36_RS17145
uniprot id: A0A0G4JS51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

1109412:AWC36 RS02655
gene id: 1109412:AWC36_RS02655
uniprot id: A0A250BAA7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1109412:AWC36 RS00730
gene id: 1109412:AWC36_RS00730
uniprot id: A0A250BL83
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

1109412:AWC36 RS08995
gene id: 1109412:AWC36_RS08995
uniprot id: A0A250BDJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M23B family.
messages: Membrane

1109412:AWC36 RS20545
gene id: 1109412:AWC36_RS20545
uniprot id: A0A250BJH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS08570
gene id: 1109412:AWC36_RS08570
uniprot id: A0A0G4K1J5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1109412:AWC36 RS09030
gene id: 1109412:AWC36_RS09030
uniprot id: A0A0G4K169
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1109412:AWC36 RS08100
gene id: 1109412:AWC36_RS08100
uniprot id: A0A0G4K0S6
names: Similarity
messages: Belongs to the UPF0263 family.

1109412:AWC36 RS20445
gene id: 1109412:AWC36_RS20445
uniprot id: A0A0G4JU42
names: Similarity
messages: Belongs to the thioredoxin family.

1109412:AWC36 RS09800
gene id: 1109412:AWC36_RS09800
uniprot id: A0A0G4K209
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS22405
gene id: 1109412:AWC36_RS22405
uniprot id: A0A0G4JVD3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1109412:AWC36 RS22395
gene id: 1109412:AWC36_RS22395
uniprot id: A0A0G4JV68
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1109412:AWC36 RS02045
gene id: 1109412:AWC36_RS02045
uniprot id: A0A0G4JWV6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1109412:AWC36 RS22780
gene id: 1109412:AWC36_RS22780
uniprot id: A0A0G4JV87
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1109412:AWC36 RS12715
gene id: 1109412:AWC36_RS12715
uniprot id: A0A250BF25
names: Similarity
messages: Belongs to the catalase family.

1109412:AWC36 RS00895
gene id: 1109412:AWC36_RS00895
uniprot id: A0A0G4JWD2
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS22455
gene id: 1109412:AWC36_RS22455
uniprot id: A0A250BJX8
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1109412:AWC36 RS13035
gene id: 1109412:AWC36_RS13035
uniprot id: A0A0G4JPL7
names: Subcellular Location Annotation
messages: Cell inner membrane

1109412:AWC36 RS17830
gene id: 1109412:AWC36_RS17830
uniprot id: A0A0G4JSI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
messages: Cell inner membrane
messages: Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+). May be involved in zinc and iron detoxification by efflux.
messages: Homodimer.
messages: Membrane

1109412:AWC36 RS20165
gene id: 1109412:AWC36_RS20165
uniprot id: A0A0G4JU06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm
messages: Homodimer.

1109412:AWC36 RS15995
gene id: 1109412:AWC36_RS15995
uniprot id: A0A0G4JRG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1109412:AWC36 RS02150
gene id: 1109412:AWC36_RS02150
uniprot id: A0A250BA55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity. Interacts with IscU.

1109412:AWC36 RS01380
gene id: 1109412:AWC36_RS01380
uniprot id: A0A0G4JX63
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Homotetramer.

1109412:AWC36 RS15390
gene id: 1109412:AWC36_RS15390
uniprot id: A0A0G4JR82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS19410
gene id: 1109412:AWC36_RS19410
uniprot id: A0A0G4JTL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS06530
gene id: 1109412:AWC36_RS06530
uniprot id: A0A0G4JZJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.

1109412:AWC36 RS06945
gene id: 1109412:AWC36_RS06945
uniprot id: A0A0G4K030
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1109412:AWC36 RS16705
gene id: 1109412:AWC36_RS16705
uniprot id: A0A0G4JRW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1109412:AWC36 RS17735
gene id: 1109412:AWC36_RS17735
uniprot id: A0A0G4JSI8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1109412:AWC36 RS02230
gene id: 1109412:AWC36_RS02230
uniprot id: A0A0G4JWY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS21440
gene id: 1109412:AWC36_RS21440
uniprot id: A0A250BJX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1109412:AWC36 RS08210
gene id: 1109412:AWC36_RS08210
uniprot id: A0A0G4K0L1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Binds two Mg(2+) per subunit.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1109412:AWC36 RS17995
gene id: 1109412:AWC36_RS17995
uniprot id: A0A0G4JSL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS08240
gene id: 1109412:AWC36_RS08240
uniprot id: A0A250BCV3
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1109412:AWC36 RS08500
gene id: 1109412:AWC36_RS08500
uniprot id: A0A0G4K0V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS09720
gene id: 1109412:AWC36_RS09720
uniprot id: A0A0G4K2G2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

1109412:AWC36 RS17215
gene id: 1109412:AWC36_RS17215
uniprot id: A0A0G4JS71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1109412:AWC36 RS20375
gene id: 1109412:AWC36_RS20375
uniprot id: A0A250BIW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS06760
gene id: 1109412:AWC36_RS06760
uniprot id: A0A0G4JZR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1109412:AWC36 RS04880
gene id: 1109412:AWC36_RS04880
uniprot id: A0A0G4JZN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS08215
gene id: 1109412:AWC36_RS08215
uniprot id: A0A0G4K0P8
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1109412:AWC36 RS12055
gene id: 1109412:AWC36_RS12055
uniprot id: A0A0G4JP64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1109412:AWC36 RS20825
gene id: 1109412:AWC36_RS20825
uniprot id: A0A0G4JUD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1109412:AWC36 RS02190
gene id: 1109412:AWC36_RS02190
uniprot id: A0A0G4JX19
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1109412:AWC36 RS13100
gene id: 1109412:AWC36_RS13100
uniprot id: A0A0G4JPP4
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1109412:AWC36 RS09210
gene id: 1109412:AWC36_RS09210
uniprot id: A0A0G4K1D6
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1109412:AWC36 RS14900
gene id: 1109412:AWC36_RS14900
uniprot id: A0A0G4JRG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS14350
gene id: 1109412:AWC36_RS14350
uniprot id: A0A0G4JR49
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS09830
gene id: 1109412:AWC36_RS09830
uniprot id: A0A250BEJ1
names: Similarity
messages: Belongs to the peptidase C40 family.

1109412:AWC36 RS20105
gene id: 1109412:AWC36_RS20105
uniprot id: A0A0G4JU16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1109412:AWC36 RS19155
gene id: 1109412:AWC36_RS19155
uniprot id: A0A0G4JU07
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1109412:AWC36 RS05890
gene id: 1109412:AWC36_RS05890
uniprot id: A0A0G4JZG6
names: Similarity
messages: Belongs to the HesB/IscA family.

1109412:AWC36 RS02130
gene id: 1109412:AWC36_RS02130
uniprot id: A0A0G4JXG1
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster.
messages: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.

1109412:AWC36 RS16380
gene id: 1109412:AWC36_RS16380
uniprot id: A0A250BLI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1109412:AWC36 RS08410
gene id: 1109412:AWC36_RS08410
uniprot id: A0A0G4K109
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS17185
gene id: 1109412:AWC36_RS17185
uniprot id: A0A0G4JS87
names: Similarity
messages: Belongs to the UPF0307 family.

1109412:AWC36 RS22490
gene id: 1109412:AWC36_RS22490
uniprot id: A0A0G4JV88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS14605
gene id: 1109412:AWC36_RS14605
uniprot id: A0A250BGJ3
names: Subunit
messages: Homodimer.

1109412:AWC36 RS13865
gene id: 1109412:AWC36_RS13865
uniprot id: A0A0G4JQS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1109412:AWC36 RS13080
gene id: 1109412:AWC36_RS13080
uniprot id: A0A0G4JQ46
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

1109412:AWC36 RS09450
gene id: 1109412:AWC36_RS09450
uniprot id: A0A0G4K1T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1109412:AWC36 RS16680
gene id: 1109412:AWC36_RS16680
uniprot id: A0A0G4JS00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1109412:AWC36 RS14480
gene id: 1109412:AWC36_RS14480
uniprot id: A0A0G4JQK8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS01385
gene id: 1109412:AWC36_RS01385
uniprot id: A0A0G4JWH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1109412:AWC36 RS03220
gene id: 1109412:AWC36_RS03220
uniprot id: A0A0G4JXP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS20100
gene id: 1109412:AWC36_RS20100
uniprot id: A0A250BLY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1109412:AWC36 RS17575
gene id: 1109412:AWC36_RS17575
uniprot id: A0A250BHJ3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1109412:AWC36 RS09350
gene id: 1109412:AWC36_RS09350
uniprot id: A0A0G4K1S0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.
messages: Feedback inhibited by histidine.

1109412:AWC36 RS08145
gene id: 1109412:AWC36_RS08145
uniprot id: A0A0G4K0N5
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1109412:AWC36 RS20450
gene id: 1109412:AWC36_RS20450
uniprot id: A0A0G4JUN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

1109412:AWC36 RS15500
gene id: 1109412:AWC36_RS15500
uniprot id: A0A0G4JR70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1109412:AWC36 RS03260
gene id: 1109412:AWC36_RS03260
uniprot id: A0A0G4JYF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1109412:AWC36 RS16865
gene id: 1109412:AWC36_RS16865
uniprot id: A0A0G4JS06
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1109412:AWC36 RS19990
gene id: 1109412:AWC36_RS19990
uniprot id: A0A0G4JTS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1109412:AWC36 RS15355
gene id: 1109412:AWC36_RS15355
uniprot id: A0A250BLT9
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1109412:AWC36 RS17755
gene id: 1109412:AWC36_RS17755
uniprot id: A0A0G4JSG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

1109412:AWC36 RS21200
gene id: 1109412:AWC36_RS21200
uniprot id: A0A0G4JUM7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DamX family.
messages: Cell inner membrane
messages: Non-essential cell division protein.
messages: The SPOR domain binds septal peptidoglycans and is required to target DamX to the septal ring.

1109412:AWC36 RS12550
gene id: 1109412:AWC36_RS12550
uniprot id: A0A0G4JPB9
names: Similarity
messages: Belongs to the ArsC family.

1109412:AWC36 RS07170
gene id: 1109412:AWC36_RS07170
uniprot id: A0A0G4K0U9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1109412:AWC36 RS14115
gene id: 1109412:AWC36_RS14115
uniprot id: A0A0G4JQD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell membrane

1109412:AWC36 RS18780
gene id: 1109412:AWC36_RS18780
uniprot id: A0A0G4JT17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1109412:AWC36 RS09705
gene id: 1109412:AWC36_RS09705
uniprot id: A0A250BDU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1109412:AWC36 RS01445
gene id: 1109412:AWC36_RS01445
uniprot id: A0A0G4JWG2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1109412:AWC36 RS20440
gene id: 1109412:AWC36_RS20440
uniprot id: A0A0G4JU29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1109412:AWC36 RS03310
gene id: 1109412:AWC36_RS03310
uniprot id: A0A0G4JYG1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Membrane

1109412:AWC36 RS10020
gene id: 1109412:AWC36_RS10020
uniprot id: A0A250BDZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1109412:AWC36 RS05530
gene id: 1109412:AWC36_RS05530
uniprot id: A0A0G4JZV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

1109412:AWC36 RS17375
gene id: 1109412:AWC36_RS17375
uniprot id: A0A0G4JS95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS00970
gene id: 1109412:AWC36_RS00970
uniprot id: A0A0G4JWE7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1109412:AWC36 RS20195
gene id: 1109412:AWC36_RS20195
uniprot id: A0A250BIU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1109412:AWC36 RS16535
gene id: 1109412:AWC36_RS16535
uniprot id: A0A0G4JRT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

1109412:AWC36 RS08700
gene id: 1109412:AWC36_RS08700
uniprot id: A0A0G4K170
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1109412:AWC36 RS02955
gene id: 1109412:AWC36_RS02955
uniprot id: A0A0G4JXM3
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS11910
gene id: 1109412:AWC36_RS11910
uniprot id: A0A0G4JPM5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS21705
gene id: 1109412:AWC36_RS21705
uniprot id: A0A250BLQ6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Activates expression of the rhaSR operon in response to L-rhamnose.
messages: Binds DNA as a dimer.
messages: Cytoplasm

1109412:AWC36 RS05745
gene id: 1109412:AWC36_RS05745
uniprot id: A0A0G4JZD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1109412:AWC36 RS22520
gene id: 1109412:AWC36_RS22520
uniprot id: A0A0G4JV73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

1109412:AWC36 RS13155
gene id: 1109412:AWC36_RS13155
uniprot id: A0A0G4JPP1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1109412:AWC36 RS17570
gene id: 1109412:AWC36_RS17570
uniprot id: A0A0G4JSD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1109412:AWC36 RS05915
gene id: 1109412:AWC36_RS05915
uniprot id: A0A0G4JZH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SufE family.
messages: Cytoplasm
messages: Homodimer. Interacts with SufS.
messages: Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.

1109412:AWC36 RS22790
gene id: 1109412:AWC36_RS22790
uniprot id: A0A0G4JVW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1109412:AWC36 RS20880
gene id: 1109412:AWC36_RS20880
uniprot id: A0A0G4JUG0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS19980
gene id: 1109412:AWC36_RS19980
uniprot id: A0A250BJ38
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1109412:AWC36 RS23325
gene id: 1109412:AWC36_RS23325
uniprot id: A0A0G4JVK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecM family.
messages: Periplasm
messages: Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation.
messages: cytosol

1109412:AWC36 RS20050
gene id: 1109412:AWC36_RS20050
uniprot id: A0A0G4JTU5
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. KdkA/rfaP family.
messages: Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core.

1109412:AWC36 RS07525
gene id: 1109412:AWC36_RS07525
uniprot id: A0A0G4K0A3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1109412:AWC36 RS09290
gene id: 1109412:AWC36_RS09290
uniprot id: A0A0G4K1R1
names: Similarity
messages: Belongs to the UPF0265 family.

1109412:AWC36 RS22445
gene id: 1109412:AWC36_RS22445
uniprot id: A0A250BLK0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

1109412:AWC36 RS11730
gene id: 1109412:AWC36_RS11730
uniprot id: A0A0G4JP02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS02570
gene id: 1109412:AWC36_RS02570
uniprot id: A0A250BA08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS08075
gene id: 1109412:AWC36_RS08075
uniprot id: A0A0G4K0S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Homodimer. Forms a complex with the accessory proteins ExbB and ExbD.
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1109412:AWC36 RS03455
gene id: 1109412:AWC36_RS03455
uniprot id: A0A0G4JXW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1109412:AWC36 RS06800
gene id: 1109412:AWC36_RS06800
uniprot id: A0A0G4K004
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1109412:AWC36 RS13670
gene id: 1109412:AWC36_RS13670
uniprot id: A0A0G4JQ01
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

1109412:AWC36 RS16875
gene id: 1109412:AWC36_RS16875
uniprot id: A0A0G4JS03
names: Subunit
messages: Monomer.

1109412:AWC36 RS03830
gene id: 1109412:AWC36_RS03830
uniprot id: A0A0G4JY49
names: Similarity
messages: Belongs to the NadC/ModD family.

1109412:AWC36 RS01920
gene id: 1109412:AWC36_RS01920
uniprot id: A0A0G4JXB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1109412:AWC36 RS10770
gene id: 1109412:AWC36_RS10770
uniprot id: A0A0G4K2H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS01780
gene id: 1109412:AWC36_RS01780
uniprot id: A0A0G4JWQ6
names: Similarity
messages: Belongs to the CdaR family.

1109412:AWC36 RS00720
gene id: 1109412:AWC36_RS00720
uniprot id: A0A0G4JWX4
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1109412:AWC36 RS13235
gene id: 1109412:AWC36_RS13235
uniprot id: A0A0G4JPV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1109412:AWC36 RS18760
gene id: 1109412:AWC36_RS18760
uniprot id: A0A0G4JT26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1109412:AWC36 RS20345
gene id: 1109412:AWC36_RS20345
uniprot id: A0A0G4JTZ4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS16590
gene id: 1109412:AWC36_RS16590
uniprot id: A0A0G4JRU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS17135
gene id: 1109412:AWC36_RS17135
uniprot id: A0A0G4JS55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1109412:AWC36 RS08290
gene id: 1109412:AWC36_RS08290
uniprot id: A0A0G4K0W6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

1109412:AWC36 RS18820
gene id: 1109412:AWC36_RS18820
uniprot id: A0A0G4JTU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1109412:AWC36 RS09245
gene id: 1109412:AWC36_RS09245
uniprot id: A0A0G4K1K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukF family.
messages: Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
messages: nucleoid

1109412:AWC36 RS10740
gene id: 1109412:AWC36_RS10740
uniprot id: A0A0G4K2A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

1109412:AWC36 RS08000
gene id: 1109412:AWC36_RS08000
uniprot id: A0A0G4K0R2
names: Similarity
messages: Belongs to the CmpA/NrtA family.

1109412:AWC36 RS16550
gene id: 1109412:AWC36_RS16550
uniprot id: A0A0G4JRU1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1109412:AWC36 RS01485
gene id: 1109412:AWC36_RS01485
uniprot id: A0A0G4JWJ7
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1109412:AWC36 RS12490
gene id: 1109412:AWC36_RS12490
uniprot id: A0A0G4JPD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1109412:AWC36 RS18505
gene id: 1109412:AWC36_RS18505
uniprot id: A0A0G4JTI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

1109412:AWC36 RS22885
gene id: 1109412:AWC36_RS22885
uniprot id: A0A250BKI8
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1109412:AWC36 RS03875
gene id: 1109412:AWC36_RS03875
uniprot id: A0A0G4JY03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS05590
gene id: 1109412:AWC36_RS05590
uniprot id: A0A0G4JZ70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1109412:AWC36 RS06830
gene id: 1109412:AWC36_RS06830
uniprot id: A0A0G4K014
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
messages: Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis.

1109412:AWC36 RS20540
gene id: 1109412:AWC36_RS20540
uniprot id: A0A0G4JU58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS01085
gene id: 1109412:AWC36_RS01085
uniprot id: A0A0G4JWJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

1109412:AWC36 RS12040
gene id: 1109412:AWC36_RS12040
uniprot id: A0A0G4JP49
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1109412:AWC36 RS09745
gene id: 1109412:AWC36_RS09745
uniprot id: A0A0G4K2G8
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1109412:AWC36 RS15770
gene id: 1109412:AWC36_RS15770
uniprot id: A0A250BH39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1109412:AWC36 RS13265
gene id: 1109412:AWC36_RS13265
uniprot id: A0A0G4JPS0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1109412:AWC36 RS08785
gene id: 1109412:AWC36_RS08785
uniprot id: A0A0G4K108
names: Subcellular Location Annotation
messages: Secreted

1109412:AWC36 RS11550
gene id: 1109412:AWC36_RS11550
uniprot id: A0A0G4K3G2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS16315
gene id: 1109412:AWC36_RS16315
uniprot id: A0A0G4JSE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1109412:AWC36 RS15955
gene id: 1109412:AWC36_RS15955
uniprot id: A0A0G4JRG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1109412:AWC36 RS04275
gene id: 1109412:AWC36_RS04275
uniprot id: A0A0G4JYI9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1109412:AWC36 RS01615
gene id: 1109412:AWC36_RS01615
uniprot id: A0A0G4JWL5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1109412:AWC36 RS04955
gene id: 1109412:AWC36_RS04955
uniprot id: A0A0G4JYX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS06215
gene id: 1109412:AWC36_RS06215
uniprot id: A0A0G4JZI5
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS17170
gene id: 1109412:AWC36_RS17170
uniprot id: A0A0G4JS63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RapZ-like family. RapZ subfamily.
messages: Homotrimer.
messages: Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.

1109412:AWC36 RS02185
gene id: 1109412:AWC36_RS02185
uniprot id: A0A0G4JWY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1109412:AWC36 RS09880
gene id: 1109412:AWC36_RS09880
uniprot id: A0A0G4K2J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1109412:AWC36 RS23305
gene id: 1109412:AWC36_RS23305
uniprot id: A0A0G4JVK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1109412:AWC36 RS15865
gene id: 1109412:AWC36_RS15865
uniprot id: A0A0G4JRY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1109412:AWC36 RS16595
gene id: 1109412:AWC36_RS16595
uniprot id: A0A250BH18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS18000
gene id: 1109412:AWC36_RS18000
uniprot id: A0A0G4JSP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1109412:AWC36 RS17750
gene id: 1109412:AWC36_RS17750
uniprot id: A0A0G4JT20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

1109412:AWC36 RS10945
gene id: 1109412:AWC36_RS10945
uniprot id: A0A0G4K2E9
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS09020
gene id: 1109412:AWC36_RS09020
uniprot id: A0A0G4K1E8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1109412:AWC36 RS08430
gene id: 1109412:AWC36_RS08430
uniprot id: A0A0G4K0Z6
names: Subcellular Location Annotation
messages: Cytoplasm

1109412:AWC36 RS01745
gene id: 1109412:AWC36_RS01745
uniprot id: A0A0G4JWS8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1109412:AWC36 RS20175
gene id: 1109412:AWC36_RS20175
uniprot id: A0A0G4JTZ3
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1109412:AWC36 RS10215
gene id: 1109412:AWC36_RS10215
uniprot id: A0A0G4K204
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1109412:AWC36 RS09520
gene id: 1109412:AWC36_RS09520
uniprot id: A0A0G4K1V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1109412:AWC36 RS19360
gene id: 1109412:AWC36_RS19360
uniprot id: A0A250BIE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

1109412:AWC36 RS08225
gene id: 1109412:AWC36_RS08225
uniprot id: A0A0G4K0W7
names: Similarity
messages: Belongs to the asparaginase 1 family.

1109412:AWC36 RS17245
gene id: 1109412:AWC36_RS17245
uniprot id: A0A0G4JS73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1109412:AWC36 RS06655
gene id: 1109412:AWC36_RS06655
uniprot id: A0A250BC15
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1109412:AWC36 RS16860
gene id: 1109412:AWC36_RS16860
uniprot id: A0A0G4JRZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

1109412:AWC36 RS07890
gene id: 1109412:AWC36_RS07890
uniprot id: A0A0G4K0E4
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

1109412:AWC36 RS01440
gene id: 1109412:AWC36_RS01440
uniprot id: A0A0G4JWM1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1109412:AWC36 RS12000
gene id: 1109412:AWC36_RS12000
uniprot id: A0A250BER5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1109412:AWC36 RS13870
gene id: 1109412:AWC36_RS13870
uniprot id: A0A0G4JQ61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1109412:AWC36 RS12695
gene id: 1109412:AWC36_RS12695
uniprot id: A0A0G4JPH9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1109412:AWC36 RS12105
gene id: 1109412:AWC36_RS12105
uniprot id: A0A0G4JP57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1109412:AWC36 RS05600
gene id: 1109412:AWC36_RS05600
uniprot id: A0A0G4JZC7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1109412:AWC36 RS21370
gene id: 1109412:AWC36_RS21370
uniprot id: A0A0G4JUQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrF/TusC family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

1109412:AWC36 RS14165
gene id: 1109412:AWC36_RS14165
uniprot id: A0A0G4JR13
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS17685
gene id: 1109412:AWC36_RS17685
uniprot id: A0A0G4JSD9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS12790
gene id: 1109412:AWC36_RS12790
uniprot id: A0A0G4JPG1
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1109412:AWC36 RS01875
gene id: 1109412:AWC36_RS01875
uniprot id: A0A0G4JWR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

1109412:AWC36 RS21710
gene id: 1109412:AWC36_RS21710
uniprot id: A0A0G4JUW3
names: Similarity
messages: Belongs to the aspartokinase family.

1109412:AWC36 RS17475
gene id: 1109412:AWC36_RS17475
uniprot id: A0A0G4JSA4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1109412:AWC36 RS20005
gene id: 1109412:AWC36_RS20005
uniprot id: A0A250BIQ3
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1109412:AWC36 RS05400
gene id: 1109412:AWC36_RS05400
uniprot id: A0A0G4JZA1
names: Subcellular Location Annotation
messages: Cell inner membrane

1109412:AWC36 RS13185
gene id: 1109412:AWC36_RS13185
uniprot id: A0A0G4JPU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1109412:AWC36 RS07885
gene id: 1109412:AWC36_RS07885
uniprot id: A0A0G4K0Q5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.
messages: Homohexamer.

1109412:AWC36 RS00305
gene id: 1109412:AWC36_RS00305
uniprot id: A0A250B9C4
names: Function
names: Subunit
messages: Hexamer of two alpha, two beta, and two delta chains.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein (component 2) and a component 1 which is either a molybdenum-iron protein, a vanadium-iron, or an iron-iron protein.

1109412:AWC36 RS20745
gene id: 1109412:AWC36_RS20745
uniprot id: A0A0G4JUA7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS20080
gene id: 1109412:AWC36_RS20080
uniprot id: A0A0G4JTY5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

1109412:AWC36 RS22880
gene id: 1109412:AWC36_RS22880
uniprot id: A0A250BKM9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1109412:AWC36 RS07070
gene id: 1109412:AWC36_RS07070
uniprot id: A0A250BC90
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1109412:AWC36 RS21195
gene id: 1109412:AWC36_RS21195
uniprot id: A0A0G4JUI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1109412:AWC36 RS08250
gene id: 1109412:AWC36_RS08250
uniprot id: A0A0G4K0X3
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

1109412:AWC36 RS00670
gene id: 1109412:AWC36_RS00670
uniprot id: A0A0G4JWA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS13905
gene id: 1109412:AWC36_RS13905
uniprot id: A0A0G4JQT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1109412:AWC36 RS21490
gene id: 1109412:AWC36_RS21490
uniprot id: A0A0G4JUW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1109412:AWC36 RS17090
gene id: 1109412:AWC36_RS17090
uniprot id: A0A0G4JS72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

1109412:AWC36 RS23335
gene id: 1109412:AWC36_RS23335
uniprot id: A0A0G4JW91
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1109412:AWC36 RS01665
gene id: 1109412:AWC36_RS01665
uniprot id: A0A0G4JWM8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1109412:AWC36 RS10735
gene id: 1109412:AWC36_RS10735
uniprot id: A0A0G4K289
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: 4-aminobutanal can spontaneously cyclize to 1-pyrroline, and 5-aminopentanal to 1-piperideine.
messages: Belongs to the aldehyde dehydrogenase family. Gamma-aminobutyraldehyde dehydrogenase subfamily.
messages: Catalyzes the oxidation 4-aminobutanal (gamma-aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4-aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS23250
gene id: 1109412:AWC36_RS23250
uniprot id: A0A0G4JVH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1109412:AWC36 RS05370
gene id: 1109412:AWC36_RS05370
uniprot id: A0A0G4JZ75
names: Similarity
messages: Belongs to the peptidase S16 family.

1109412:AWC36 RS23270
gene id: 1109412:AWC36_RS23270
uniprot id: A0A0G4JVJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS10185
gene id: 1109412:AWC36_RS10185
uniprot id: A0A0G4K1Z9
names: Subcellular Location Annotation
messages: Cell inner membrane

1109412:AWC36 RS09500
gene id: 1109412:AWC36_RS09500
uniprot id: A0A0G4K1K6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1109412:AWC36 RS17180
gene id: 1109412:AWC36_RS17180
uniprot id: A0A0G4JS62
names: Similarity
messages: Belongs to the peptidase U62 family.

1109412:AWC36 RS16695
gene id: 1109412:AWC36_RS16695
uniprot id: A0A0G4JRX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1109412:AWC36 RS13145
gene id: 1109412:AWC36_RS13145
uniprot id: A0A0G4JPQ3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1109412:AWC36 RS21530
gene id: 1109412:AWC36_RS21530
uniprot id: A0A250BJH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1109412:AWC36 RS00830
gene id: 1109412:AWC36_RS00830
uniprot id: A0A0G4JWD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1109412:AWC36 RS16935
gene id: 1109412:AWC36_RS16935
uniprot id: A0A250BHD3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.

1109412:AWC36 RS16330
gene id: 1109412:AWC36_RS16330
uniprot id: A0A0G4JRP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

1109412:AWC36 RS21590
gene id: 1109412:AWC36_RS21590
uniprot id: A0A0G4JUU6
names: Similarity
messages: Belongs to the Smg family.

1109412:AWC36 RS07695
gene id: 1109412:AWC36_RS07695
uniprot id: A0A0G4K0L0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1109412:AWC36 RS10620
gene id: 1109412:AWC36_RS10620
uniprot id: A0A0G4K264
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS23280
gene id: 1109412:AWC36_RS23280
uniprot id: A0A0G4JVK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1109412:AWC36 RS17850
gene id: 1109412:AWC36_RS17850
uniprot id: A0A0G4JSH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Interacts with IscS.
messages: Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.

1109412:AWC36 RS09370
gene id: 1109412:AWC36_RS09370
uniprot id: A0A0G4K1P2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1109412:AWC36 RS13800
gene id: 1109412:AWC36_RS13800
uniprot id: A0A250BG09
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

1109412:AWC36 RS21230
gene id: 1109412:AWC36_RS21230
uniprot id: A0A0G4JV94
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1109412:AWC36 RS12375
gene id: 1109412:AWC36_RS12375
uniprot id: A0A0G4JPB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1109412:AWC36 RS05895
gene id: 1109412:AWC36_RS05895
uniprot id: A0A250BCK3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1109412:AWC36 RS05925
gene id: 1109412:AWC36_RS05925
uniprot id: A0A0G4JZC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

1109412:AWC36 RS01785
gene id: 1109412:AWC36_RS01785
uniprot id: A0A250BL93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1109412:AWC36 RS11985
gene id: 1109412:AWC36_RS11985
uniprot id: A0A0G4JP23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
messages: Belongs to the AcrZ family.
messages: Cell membrane
messages: Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB.

1109412:AWC36 RS07410
gene id: 1109412:AWC36_RS07410
uniprot id: A0A0G4K0F0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1109412:AWC36 RS20700
gene id: 1109412:AWC36_RS20700
uniprot id: A0A0G4JUC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

1109412:AWC36 RS09385
gene id: 1109412:AWC36_RS09385
uniprot id: A0A250BL12
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1109412:AWC36 RS09205
gene id: 1109412:AWC36_RS09205
uniprot id: A0A0G4K211
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

1109412:AWC36 RS06820
gene id: 1109412:AWC36_RS06820
uniprot id: A0A0G4JZW2
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS19115
gene id: 1109412:AWC36_RS19115
uniprot id: A0A0G4JTF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1109412:AWC36 RS12030
gene id: 1109412:AWC36_RS12030
uniprot id: A0A0G4JP60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1109412:AWC36 RS14630
gene id: 1109412:AWC36_RS14630
uniprot id: A0A250BGA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

1109412:AWC36 RS17085
gene id: 1109412:AWC36_RS17085
uniprot id: A0A250BHM9
names: Similarity
messages: Belongs to the peptidase S1C family.

1109412:AWC36 RS08175
gene id: 1109412:AWC36_RS08175
uniprot id: A0A250BD53
names: Similarity
messages: Belongs to the UPF0225 family.

1109412:AWC36 RS21700
gene id: 1109412:AWC36_RS21700
uniprot id: A0A0G4JVI4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Activates expression of the rhaBAD and rhaT operons.
messages: Binds DNA as a dimer.
messages: Cytoplasm

1109412:AWC36 RS00795
gene id: 1109412:AWC36_RS00795
uniprot id: A0A0G4JWC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

1109412:AWC36 RS17895
gene id: 1109412:AWC36_RS17895
uniprot id: A0A0G4JSM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1109412:AWC36 RS14595
gene id: 1109412:AWC36_RS14595
uniprot id: A0A0G4JQM6
names: Similarity
messages: Belongs to the UPF0178 family.

1109412:AWC36 RS18770
gene id: 1109412:AWC36_RS18770
uniprot id: A0A0G4JT23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1109412:AWC36 RS03250
gene id: 1109412:AWC36_RS03250
uniprot id: A0A250BL77
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS13215
gene id: 1109412:AWC36_RS13215
uniprot id: A0A0G4JPR0
names: Similarity
messages: Belongs to the UPF0234 family.

1109412:AWC36 RS05685
gene id: 1109412:AWC36_RS05685
uniprot id: A0A0G4JZX9
names: Function
names: Similarity
messages: Belongs to the thiamine kinase family.
messages: Catalyzes the phosphorylation of thiamine to thiamine phosphate.

1109412:AWC36 RS01030
gene id: 1109412:AWC36_RS01030
uniprot id: A0A0G4JX37
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1109412:AWC36 RS06780
gene id: 1109412:AWC36_RS06780
uniprot id: A0A0G4K009
names: Function
names: Subunit
messages: Homodimer.
messages: Required for resistance to the phenazine antibiotic.

1109412:AWC36 RS09250
gene id: 1109412:AWC36_RS09250
uniprot id: A0A0G4K1B2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.

1109412:AWC36 RS16925
gene id: 1109412:AWC36_RS16925
uniprot id: A0A0G4JS13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1109412:AWC36 RS02715
gene id: 1109412:AWC36_RS02715
uniprot id: A0A0G4JXB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1109412:AWC36 RS18460
gene id: 1109412:AWC36_RS18460
uniprot id: A0A0G4JSU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1109412:AWC36 RS12145
gene id: 1109412:AWC36_RS12145
uniprot id: A0A0G4JP51
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1109412:AWC36 RS09305
gene id: 1109412:AWC36_RS09305
uniprot id: A0A0G4K1J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1109412:AWC36 RS02125
gene id: 1109412:AWC36_RS02125
uniprot id: A0A0G4JWU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1109412:AWC36 RS13760
gene id: 1109412:AWC36_RS13760
uniprot id: A0A250BG24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1109412:AWC36 RS09840
gene id: 1109412:AWC36_RS09840
uniprot id: A0A0G4K1Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS15530
gene id: 1109412:AWC36_RS15530
uniprot id: A0A250BLH6
names: Similarity
messages: Belongs to the UPF0213 family.

1109412:AWC36 RS04345
gene id: 1109412:AWC36_RS04345
uniprot id: A0A0G4JYK9
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1109412:AWC36 RS01460
gene id: 1109412:AWC36_RS01460
uniprot id: A0A0G4JWJ1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1109412:AWC36 RS11055
gene id: 1109412:AWC36_RS11055
uniprot id: A0A0G4K2G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1109412:AWC36 RS07930
gene id: 1109412:AWC36_RS07930
uniprot id: A0A0G4K0P9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS15620
gene id: 1109412:AWC36_RS15620
uniprot id: A0A250BGJ4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

1109412:AWC36 RS03115
gene id: 1109412:AWC36_RS03115
uniprot id: A0A0G4JXM9
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS22500
gene id: 1109412:AWC36_RS22500
uniprot id: A0A0G4JV91
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1109412:AWC36 RS21480
gene id: 1109412:AWC36_RS21480
uniprot id: A0A0G4JUS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1109412:AWC36 RS12885
gene id: 1109412:AWC36_RS12885
uniprot id: A0A0G4JPJ9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1109412:AWC36 RS01750
gene id: 1109412:AWC36_RS01750
uniprot id: A0A0G4JWL4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1109412:AWC36 RS02205
gene id: 1109412:AWC36_RS02205
uniprot id: A0A0G4JWY0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1109412:AWC36 RS01355
gene id: 1109412:AWC36_RS01355
uniprot id: A0A250B9P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS14505
gene id: 1109412:AWC36_RS14505
uniprot id: A0A0G4JQL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS16435
gene id: 1109412:AWC36_RS16435
uniprot id: A0A250BGY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS15980
gene id: 1109412:AWC36_RS15980
uniprot id: A0A0G4JS19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1109412:AWC36 RS09610
gene id: 1109412:AWC36_RS09610
uniprot id: A0A0G4K1T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1109412:AWC36 RS14665
gene id: 1109412:AWC36_RS14665
uniprot id: A0A250BG30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1109412:AWC36 RS13615
gene id: 1109412:AWC36_RS13615
uniprot id: A0A0G4JQ29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1109412:AWC36 RS19985
gene id: 1109412:AWC36_RS19985
uniprot id: A0A0G4JTW4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1109412:AWC36 RS17925
gene id: 1109412:AWC36_RS17925
uniprot id: A0A0G4JSK5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS19840
gene id: 1109412:AWC36_RS19840
uniprot id: A0A250BJ11
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

1109412:AWC36 RS16805
gene id: 1109412:AWC36_RS16805
uniprot id: A0A0G4JSN8
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS19925
gene id: 1109412:AWC36_RS19925
uniprot id: A0A0G4JTR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS20140
gene id: 1109412:AWC36_RS20140
uniprot id: A0A250BLX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate.
messages: Cytoplasm

1109412:AWC36 RS14890
gene id: 1109412:AWC36_RS14890
uniprot id: A0A0G4JQT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS15090
gene id: 1109412:AWC36_RS15090
uniprot id: A0A0G4JQY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1109412:AWC36 RS04695
gene id: 1109412:AWC36_RS04695
uniprot id: A0A0G4JYS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1109412:AWC36 RS03215
gene id: 1109412:AWC36_RS03215
uniprot id: A0A0G4JYE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1109412:AWC36 RS01870
gene id: 1109412:AWC36_RS01870
uniprot id: A0A0G4JXA8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1109412:AWC36 RS04495
gene id: 1109412:AWC36_RS04495
uniprot id: A0A0G4JYT0
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS04885
gene id: 1109412:AWC36_RS04885
uniprot id: A0A0G4JYZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS15915
gene id: 1109412:AWC36_RS15915
uniprot id: A0A0G4JRF0
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS06150
gene id: 1109412:AWC36_RS06150
uniprot id: A0A0G4JZD7
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1109412:AWC36 RS15655
gene id: 1109412:AWC36_RS15655
uniprot id: A0A250BH01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1109412:AWC36 RS20805
gene id: 1109412:AWC36_RS20805
uniprot id: A0A0G4JUA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS22380
gene id: 1109412:AWC36_RS22380
uniprot id: A0A0G4JVC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1109412:AWC36 RS12470
gene id: 1109412:AWC36_RS12470
uniprot id: A0A0G4JPA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1109412:AWC36 RS02120
gene id: 1109412:AWC36_RS02120
uniprot id: A0A0G4JX01
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1109412:AWC36 RS10480
gene id: 1109412:AWC36_RS10480
uniprot id: A0A0G4K236
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS18555
gene id: 1109412:AWC36_RS18555
uniprot id: A0A0G4JSY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1109412:AWC36 RS21745
gene id: 1109412:AWC36_RS21745
uniprot id: A0A0G4JUX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdD family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

1109412:AWC36 RS03005
gene id: 1109412:AWC36_RS03005
uniprot id: A0A0G4JXI4
names: Similarity
messages: Belongs to the UPF0115 family.

1109412:AWC36 RS13290
gene id: 1109412:AWC36_RS13290
uniprot id: A0A0G4JPS5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1109412:AWC36 RS16480
gene id: 1109412:AWC36_RS16480
uniprot id: A0A250BMF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

1109412:AWC36 RS21740
gene id: 1109412:AWC36_RS21740
uniprot id: A0A0G4JUT8
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1109412:AWC36 RS08950
gene id: 1109412:AWC36_RS08950
uniprot id: A0A0G4K1U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1109412:AWC36 RS06875
gene id: 1109412:AWC36_RS06875
uniprot id: A0A0G4JZX2
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS01880
gene id: 1109412:AWC36_RS01880
uniprot id: A0A0G4JWS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

1109412:AWC36 RS04940
gene id: 1109412:AWC36_RS04940
uniprot id: A0A0G4JZQ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS10720
gene id: 1109412:AWC36_RS10720
uniprot id: A0A0G4K284
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1109412:AWC36 RS17240
gene id: 1109412:AWC36_RS17240
uniprot id: A0A0G4JSX0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1109412:AWC36 RS12830
gene id: 1109412:AWC36_RS12830
uniprot id: A0A0G4JQ30
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS20680
gene id: 1109412:AWC36_RS20680
uniprot id: A0A0G4JUB7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1109412:AWC36 RS13310
gene id: 1109412:AWC36_RS13310
uniprot id: A0A0G4JPW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS08705
gene id: 1109412:AWC36_RS08705
uniprot id: A0A250BDB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS21415
gene id: 1109412:AWC36_RS21415
uniprot id: A0A0G4JUU7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1109412:AWC36 RS03150
gene id: 1109412:AWC36_RS03150
uniprot id: A0A0G4JXR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS23290
gene id: 1109412:AWC36_RS23290
uniprot id: A0A0G4JVN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1109412:AWC36 RS13325
gene id: 1109412:AWC36_RS13325
uniprot id: A0A250BFL6
names: Function
names: Similarity
messages: Belongs to the AcpH family.
messages: Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.

1109412:AWC36 RS12290
gene id: 1109412:AWC36_RS12290
uniprot id: A0A0G4JP73
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1109412:AWC36 RS20290
gene id: 1109412:AWC36_RS20290
uniprot id: A0A0G4JTY2
names: Similarity
messages: Belongs to the UPF0438 family.

1109412:AWC36 RS01600
gene id: 1109412:AWC36_RS01600
uniprot id: A0A0G4JWP7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1109412:AWC36 RS15925
gene id: 1109412:AWC36_RS15925
uniprot id: A0A0G4JRF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS05855
gene id: 1109412:AWC36_RS05855
uniprot id: A0A0G4JZF5
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1109412:AWC36 RS00700
gene id: 1109412:AWC36_RS00700
uniprot id: A0A0G4JWA4
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

1109412:AWC36 RS23030
gene id: 1109412:AWC36_RS23030
uniprot id: A0A250BLL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS11505
gene id: 1109412:AWC36_RS11505
uniprot id: A0A0G4K2S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS11620
gene id: 1109412:AWC36_RS11620
uniprot id: A0A0G4K2Y2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1109412:AWC36 RS09885
gene id: 1109412:AWC36_RS09885
uniprot id: A0A0G4K1Z8
names: Similarity
messages: Belongs to the PhoH family.

1109412:AWC36 RS22435
gene id: 1109412:AWC36_RS22435
uniprot id: A0A0G4JV71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1109412:AWC36 RS04780
gene id: 1109412:AWC36_RS04780
uniprot id: A0A0G4JZM1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1109412:AWC36 RS14795
gene id: 1109412:AWC36_RS14795
uniprot id: A0A250BGF7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS21475
gene id: 1109412:AWC36_RS21475
uniprot id: A0A0G4JUP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1109412:AWC36 RS16635
gene id: 1109412:AWC36_RS16635
uniprot id: A0A0G4JRV1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1109412:AWC36 RS16025
gene id: 1109412:AWC36_RS16025
uniprot id: A0A0G4JRH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CutA family.
messages: Binds 1 copper ion per subunit.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in resistance toward heavy metals.

1109412:AWC36 RS09000
gene id: 1109412:AWC36_RS09000
uniprot id: A0A0G4K1G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 9 family.
messages: Periplasm

1109412:AWC36 RS15425
gene id: 1109412:AWC36_RS15425
uniprot id: A0A0G4JR56
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1109412:AWC36 RS00745
gene id: 1109412:AWC36_RS00745
uniprot id: A0A0G4JWX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1109412:AWC36 RS14320
gene id: 1109412:AWC36_RS14320
uniprot id: A0A0G4JQI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1109412:AWC36 RS05930
gene id: 1109412:AWC36_RS05930
uniprot id: A0A250BBX8
names: Similarity
messages: Belongs to the pyruvate kinase family.

1109412:AWC36 RS21605
gene id: 1109412:AWC36_RS21605
uniprot id: A0A0G4JUU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1109412:AWC36 RS07400
gene id: 1109412:AWC36_RS07400
uniprot id: A0A0G4K0Z3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-101 inactivates the nitrogenase reductase and regulates nitrogenase activity.

1109412:AWC36 RS22375
gene id: 1109412:AWC36_RS22375
uniprot id: A0A0G4JVT3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1109412:AWC36 RS17710
gene id: 1109412:AWC36_RS17710
uniprot id: A0A0G4JSI3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

1109412:AWC36 RS12095
gene id: 1109412:AWC36_RS12095
uniprot id: A0A0G4JP68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1109412:AWC36 RS09810
gene id: 1109412:AWC36_RS09810
uniprot id: A0A0G4K1S4
names: Similarity
messages: Belongs to the elongation factor P family.

1109412:AWC36 RS16020
gene id: 1109412:AWC36_RS16020
uniprot id: A0A0G4JRH2
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1109412:AWC36 RS19745
gene id: 1109412:AWC36_RS19745
uniprot id: A0A0G4JUC2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS12600
gene id: 1109412:AWC36_RS12600
uniprot id: A0A0G4JPC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1109412:AWC36 RS20405
gene id: 1109412:AWC36_RS20405
uniprot id: A0A0G4JU39
names: Similarity
messages: Belongs to the CapA family.

1109412:AWC36 RS09335
gene id: 1109412:AWC36_RS09335
uniprot id: A0A250BDQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

1109412:AWC36 RS15520
gene id: 1109412:AWC36_RS15520
uniprot id: A0A0G4JRQ7
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS23240
gene id: 1109412:AWC36_RS23240
uniprot id: A0A0G4JVN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.
messages: nucleoid

1109412:AWC36 RS20590
gene id: 1109412:AWC36_RS20590
uniprot id: A0A0G4JU68
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1109412:AWC36 RS12045
gene id: 1109412:AWC36_RS12045
uniprot id: A0A0G4JPQ5
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS06955
gene id: 1109412:AWC36_RS06955
uniprot id: A0A0G4JZV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS12645
gene id: 1109412:AWC36_RS12645
uniprot id: A0A0G4JPD1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1109412:AWC36 RS19795
gene id: 1109412:AWC36_RS19795
uniprot id: A0A0G4JTW3
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS21080
gene id: 1109412:AWC36_RS21080
uniprot id: A0A0G4JUG1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1109412:AWC36 RS16945
gene id: 1109412:AWC36_RS16945
uniprot id: A0A0G4JSR4
names: Function
names: Similarity
names: Subunit
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.
messages: Homodimer.

1109412:AWC36 RS17780
gene id: 1109412:AWC36_RS17780
uniprot id: A0A0G4JSJ8
names: Similarity
messages: Belongs to the FBPase class 2 family.

1109412:AWC36 RS00680
gene id: 1109412:AWC36_RS00680
uniprot id: A0A0G4JWA6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS13005
gene id: 1109412:AWC36_RS13005
uniprot id: A0A0G4JPL2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1109412:AWC36 RS21085
gene id: 1109412:AWC36_RS21085
uniprot id: A0A0G4JUK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS19960
gene id: 1109412:AWC36_RS19960
uniprot id: A0A0G4JTW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

1109412:AWC36 RS15645
gene id: 1109412:AWC36_RS15645
uniprot id: A0A0G4JR98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1109412:AWC36 RS06810
gene id: 1109412:AWC36_RS06810
uniprot id: A0A0G4JZS4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS12515
gene id: 1109412:AWC36_RS12515
uniprot id: A0A0G4JPE2
names: Similarity
messages: Belongs to the UPF0250 family.

1109412:AWC36 RS01915
gene id: 1109412:AWC36_RS01915
uniprot id: A0A0G4JWP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1109412:AWC36 RS03125
gene id: 1109412:AWC36_RS03125
uniprot id: A0A0G4JXT8
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS12245
gene id: 1109412:AWC36_RS12245
uniprot id: A0A0G4JP92
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS12320
gene id: 1109412:AWC36_RS12320
uniprot id: A0A0G4JP85
names: Similarity
messages: Belongs to the asparagine synthetase family.

1109412:AWC36 RS01790
gene id: 1109412:AWC36_RS01790
uniprot id: A0A0G4JWM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1109412:AWC36 RS07425
gene id: 1109412:AWC36_RS07425
uniprot id: A0A250BLG7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS03300
gene id: 1109412:AWC36_RS03300
uniprot id: A0A0G4JXW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1109412:AWC36 RS15060
gene id: 1109412:AWC36_RS15060
uniprot id: A0A0G4JRI6
names: Similarity
messages: Belongs to the bacterial secretin family.

1109412:AWC36 RS12265
gene id: 1109412:AWC36_RS12265
uniprot id: A0A0G4JP70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

1109412:AWC36 RS12050
gene id: 1109412:AWC36_RS12050
uniprot id: A0A0G4JP36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

1109412:AWC36 RS23535
gene id: 1109412:AWC36_RS23535
uniprot id: A0A0G4JVQ3
names: Similarity
messages: Belongs to the UPF0231 family.

1109412:AWC36 RS07050
gene id: 1109412:AWC36_RS07050
uniprot id: A0A250BKX9
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS16355
gene id: 1109412:AWC36_RS16355
uniprot id: A0A0G4JSF4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1109412:AWC36 RS15340
gene id: 1109412:AWC36_RS15340
uniprot id: A0A0G4JR73
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1109412:AWC36 RS04730
gene id: 1109412:AWC36_RS04730
uniprot id: A0A250BB45
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1109412:AWC36 RS07265
gene id: 1109412:AWC36_RS07265
uniprot id: A0A0G4K070
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1109412:AWC36 RS15765
gene id: 1109412:AWC36_RS15765
uniprot id: A0A0G4JRC0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1109412:AWC36 RS04145
gene id: 1109412:AWC36_RS04145
uniprot id: A0A0G4JYG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1109412:AWC36 RS12285
gene id: 1109412:AWC36_RS12285
uniprot id: A0A0G4JPU7
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1109412:AWC36 RS23310
gene id: 1109412:AWC36_RS23310
uniprot id: A0A0G4JW88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1109412:AWC36 RS04500
gene id: 1109412:AWC36_RS04500
uniprot id: A0A0G4JYW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0299 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS16360
gene id: 1109412:AWC36_RS16360
uniprot id: A0A0G4JRQ5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1109412:AWC36 RS13655
gene id: 1109412:AWC36_RS13655
uniprot id: A0A0G4JQH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.

1109412:AWC36 RS21990
gene id: 1109412:AWC36_RS21990
uniprot id: A0A0G4JVQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1109412:AWC36 RS14405
gene id: 1109412:AWC36_RS14405
uniprot id: A0A0G4JQM9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1109412:AWC36 RS20325
gene id: 1109412:AWC36_RS20325
uniprot id: A0A0G4JUK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1109412:AWC36 RS09645
gene id: 1109412:AWC36_RS09645
uniprot id: A0A250BDS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
messages: Cell membrane

1109412:AWC36 RS19020
gene id: 1109412:AWC36_RS19020
uniprot id: A0A250BIH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

1109412:AWC36 RS05000
gene id: 1109412:AWC36_RS05000
uniprot id: A0A0G4JZ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS14310
gene id: 1109412:AWC36_RS14310
uniprot id: A0A0G4JQH6
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.

1109412:AWC36 RS17260
gene id: 1109412:AWC36_RS17260
uniprot id: A0A0G4JSX2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1109412:AWC36 RS23340
gene id: 1109412:AWC36_RS23340
uniprot id: A0A0G4JVQ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1109412:AWC36 RS21560
gene id: 1109412:AWC36_RS21560
uniprot id: A0A0G4JUQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1109412:AWC36 RS19885
gene id: 1109412:AWC36_RS19885
uniprot id: A0A250BJ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS10150
gene id: 1109412:AWC36_RS10150
uniprot id: A0A0G4K266
names: Similarity
messages: Belongs to the MotB family.

1109412:AWC36 RS08885
gene id: 1109412:AWC36_RS08885
uniprot id: A0A0G4K127
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

1109412:AWC36 RS11520
gene id: 1109412:AWC36_RS11520
uniprot id: A0A250BEH3
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1109412:AWC36 RS22360
gene id: 1109412:AWC36_RS22360
uniprot id: A0A0G4JV58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1109412:AWC36 RS16205
gene id: 1109412:AWC36_RS16205
uniprot id: A0A0G4JRM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1109412:AWC36 RS17115
gene id: 1109412:AWC36_RS17115
uniprot id: A0A0G4JS76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1109412:AWC36 RS16560
gene id: 1109412:AWC36_RS16560
uniprot id: A0A250BHG5
names: Similarity
messages: Belongs to the RutC family.

1109412:AWC36 RS19275
gene id: 1109412:AWC36_RS19275
uniprot id: A0A0G4JU28
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1109412:AWC36 RS00295
gene id: 1109412:AWC36_RS00295
uniprot id: A0A250BL27
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-100 inactivates the nitrogenase reductase and regulates nitrogenase activity.

1109412:AWC36 RS15540
gene id: 1109412:AWC36_RS15540
uniprot id: A0A0G4JR79
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

1109412:AWC36 RS12020
gene id: 1109412:AWC36_RS12020
uniprot id: A0A250BL62
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1109412:AWC36 RS22875
gene id: 1109412:AWC36_RS22875
uniprot id: A0A0G4JVD0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1109412:AWC36 RS04260
gene id: 1109412:AWC36_RS04260
uniprot id: A0A0G4JY79
names: Function
names: Similarity
messages: Belongs to the bacterial-type ferredoxin family. FixX subfamily.
messages: Could be a 3Fe-4S cluster-containing protein.

1109412:AWC36 RS05995
gene id: 1109412:AWC36_RS05995
uniprot id: A0A250BBY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1109412:AWC36 RS17415
gene id: 1109412:AWC36_RS17415
uniprot id: A0A250BHG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS13485
gene id: 1109412:AWC36_RS13485
uniprot id: A0A0G4JPW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS05345
gene id: 1109412:AWC36_RS05345
uniprot id: A0A0G4JZ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1109412:AWC36 RS23140
gene id: 1109412:AWC36_RS23140
uniprot id: A0A0G4JW56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane
messages: The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB).

1109412:AWC36 RS07920
gene id: 1109412:AWC36_RS07920
uniprot id: A0A0G4K1A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1109412:AWC36 RS05540
gene id: 1109412:AWC36_RS05540
uniprot id: A0A0G4JZ99
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1109412:AWC36 RS21580
gene id: 1109412:AWC36_RS21580
uniprot id: A0A0G4JUT7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1109412:AWC36 RS09270
gene id: 1109412:AWC36_RS09270
uniprot id: A0A0G4K1G5
names: Similarity
messages: Belongs to the UPF0434 family.

1109412:AWC36 RS01060
gene id: 1109412:AWC36_RS01060
uniprot id: A0A0G4JWJ2
names: Similarity
messages: Belongs to the YkuD family.

1109412:AWC36 RS16905
gene id: 1109412:AWC36_RS16905
uniprot id: A0A0G4JS40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1109412:AWC36 RS12525
gene id: 1109412:AWC36_RS12525
uniprot id: A0A0G4JPC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1109412:AWC36 RS20985
gene id: 1109412:AWC36_RS20985
uniprot id: A0A0G4JUH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

1109412:AWC36 RS09825
gene id: 1109412:AWC36_RS09825
uniprot id: A0A0G4K1Q2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxT phosphotransferase family.
messages: Cell inner membrane
messages: Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1-diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS21495
gene id: 1109412:AWC36_RS21495
uniprot id: A0A0G4JUS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1109412:AWC36 RS16800
gene id: 1109412:AWC36_RS16800
uniprot id: A0A0G4JRZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0299 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS15395
gene id: 1109412:AWC36_RS15395
uniprot id: A0A0G4JR47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS07270
gene id: 1109412:AWC36_RS07270
uniprot id: A0A0G4K0C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1109412:AWC36 RS17200
gene id: 1109412:AWC36_RS17200
uniprot id: A0A0G4JSW3
names: Similarity
messages: Belongs to the peptidase U62 family.

1109412:AWC36 RS00545
gene id: 1109412:AWC36_RS00545
uniprot id: A0A0G4JW40
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS18340
gene id: 1109412:AWC36_RS18340
uniprot id: A0A0G4JST4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS21525
gene id: 1109412:AWC36_RS21525
uniprot id: A0A0G4JUS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1109412:AWC36 RS06670
gene id: 1109412:AWC36_RS06670
uniprot id: A0A250BCG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SlyA family.
messages: Homodimer.
messages: Transcription regulator that can specifically activate or repress expression of target genes.

1109412:AWC36 RS00935
gene id: 1109412:AWC36_RS00935
uniprot id: A0A0G4JWE8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1109412:AWC36 RS21390
gene id: 1109412:AWC36_RS21390
uniprot id: A0A0G4JUU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1109412:AWC36 RS09155
gene id: 1109412:AWC36_RS09155
uniprot id: A0A0G4K1C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Component of a transport pathway that contributes to membrane integrity.
messages: Membrane

1109412:AWC36 RS22860
gene id: 1109412:AWC36_RS22860
uniprot id: A0A0G4JVC4
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS19145
gene id: 1109412:AWC36_RS19145
uniprot id: A0A0G4JTB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1109412:AWC36 RS09460
gene id: 1109412:AWC36_RS09460
uniprot id: A0A250BDV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1109412:AWC36 RS02440
gene id: 1109412:AWC36_RS02440
uniprot id: A0A0G4JX75
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1109412:AWC36 RS19370
gene id: 1109412:AWC36_RS19370
uniprot id: A0A250BJH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS21125
gene id: 1109412:AWC36_RS21125
uniprot id: A0A0G4JUL3
names: Subcellular Location Annotation
messages: Cell inner membrane

1109412:AWC36 RS01430
gene id: 1109412:AWC36_RS01430
uniprot id: A0A0G4JWI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1109412:AWC36 RS12485
gene id: 1109412:AWC36_RS12485
uniprot id: A0A0G4JPA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1109412:AWC36 RS20115
gene id: 1109412:AWC36_RS20115
uniprot id: A0A0G4JUH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lipid A palmitoyltransferase family.
messages: Cell outer membrane
messages: Homodimer.
messages: Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.

1109412:AWC36 RS12565
gene id: 1109412:AWC36_RS12565
uniprot id: A0A0G4JPB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0370 family.
messages: Cell membrane

1109412:AWC36 RS19560
gene id: 1109412:AWC36_RS19560
uniprot id: A0A0G4JTN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
messages: Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
messages: Cytoplasm
messages: Homodimer.

1109412:AWC36 RS08650
gene id: 1109412:AWC36_RS08650
uniprot id: A0A0G4K161
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1109412:AWC36 RS11855
gene id: 1109412:AWC36_RS11855
uniprot id: A0A0G4JP21
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1109412:AWC36 RS16850
gene id: 1109412:AWC36_RS16850
uniprot id: A0A0G4JSP5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS17290
gene id: 1109412:AWC36_RS17290
uniprot id: A0A0G4JSB2
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

1109412:AWC36 RS21765
gene id: 1109412:AWC36_RS21765
uniprot id: A0A0G4JVL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
messages: Homodimer.
messages: With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.

1109412:AWC36 RS03360
gene id: 1109412:AWC36_RS03360
uniprot id: A0A0G4JXS9
names: Similarity
messages: Belongs to the peptidase A31 family.

1109412:AWC36 RS21895
gene id: 1109412:AWC36_RS21895
uniprot id: A0A0G4JUZ2
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

1109412:AWC36 RS20320
gene id: 1109412:AWC36_RS20320
uniprot id: A0A250BJ36
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS07220
gene id: 1109412:AWC36_RS07220
uniprot id: A0A0G4K0B9
names: Subcellular Location Annotation
messages: Cell inner membrane

1109412:AWC36 RS21500
gene id: 1109412:AWC36_RS21500
uniprot id: A0A0G4JUP8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1109412:AWC36 RS16010
gene id: 1109412:AWC36_RS16010
uniprot id: A0A0G4JRH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1109412:AWC36 RS21545
gene id: 1109412:AWC36_RS21545
uniprot id: A0A0G4JUW9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1109412:AWC36 RS13110
gene id: 1109412:AWC36_RS13110
uniprot id: A0A0G4JPN2
names: Similarity
messages: Belongs to the P(II) protein family.

1109412:AWC36 RS21785
gene id: 1109412:AWC36_RS21785
uniprot id: A0A0G4JUY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1109412:AWC36 RS15630
gene id: 1109412:AWC36_RS15630
uniprot id: A0A0G4JR95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1109412:AWC36 RS06745
gene id: 1109412:AWC36_RS06745
uniprot id: A0A0G4JZU7
names: Similarity
messages: Belongs to the SUI1 family.

1109412:AWC36 RS06790
gene id: 1109412:AWC36_RS06790
uniprot id: A0A0G4K0G3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1109412:AWC36 RS12400
gene id: 1109412:AWC36_RS12400
uniprot id: A0A0G4JP94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS17395
gene id: 1109412:AWC36_RS17395
uniprot id: A0A0G4JSA0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1109412:AWC36 RS00485
gene id: 1109412:AWC36_RS00485
uniprot id: A0A0G4JW60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1109412:AWC36 RS13445
gene id: 1109412:AWC36_RS13445
uniprot id: A0A0G4JPX3
names: Similarity
messages: Belongs to the YjdM family.

1109412:AWC36 RS00135
gene id: 1109412:AWC36_RS00135
uniprot id: A0A0G4JVV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
messages: Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS18805
gene id: 1109412:AWC36_RS18805
uniprot id: A0A0G4JT24
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1109412:AWC36 RS03120
gene id: 1109412:AWC36_RS03120
uniprot id: A0A0G4JXQ3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS09790
gene id: 1109412:AWC36_RS09790
uniprot id: A0A0G4K2H4
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1109412:AWC36 RS19185
gene id: 1109412:AWC36_RS19185
uniprot id: A0A0G4JTE1
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1109412:AWC36 RS18570
gene id: 1109412:AWC36_RS18570
uniprot id: A0A0G4JTP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1109412:AWC36 RS18390
gene id: 1109412:AWC36_RS18390
uniprot id: A0A0G4JSU4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS11990
gene id: 1109412:AWC36_RS11990
uniprot id: A0A0G4JP52
names: Similarity
messages: Belongs to the ModE family.

1109412:AWC36 RS10835
gene id: 1109412:AWC36_RS10835
uniprot id: A0A0G4K2C9
names: Similarity
messages: Belongs to the HupF/HypC family.

1109412:AWC36 RS17405
gene id: 1109412:AWC36_RS17405
uniprot id: A0A0G4JS94
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1109412:AWC36 RS18960
gene id: 1109412:AWC36_RS18960
uniprot id: A0A0G4JT90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS21455
gene id: 1109412:AWC36_RS21455
uniprot id: A0A0G4JUS3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1109412:AWC36 RS14625
gene id: 1109412:AWC36_RS14625
uniprot id: A0A0G4JQN1
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1109412:AWC36 RS15720
gene id: 1109412:AWC36_RS15720
uniprot id: A0A0G4JRA9
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1109412:AWC36 RS19180
gene id: 1109412:AWC36_RS19180
uniprot id: A0A0G4JU11
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1109412:AWC36 RS12465
gene id: 1109412:AWC36_RS12465
uniprot id: A0A0G4JPD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1109412:AWC36 RS09535
gene id: 1109412:AWC36_RS09535
uniprot id: A0A0G4K1M3
names: Subcellular Location Annotation
messages: Cytoplasm

1109412:AWC36 RS20785
gene id: 1109412:AWC36_RS20785
uniprot id: A0A0G4JU97
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS20190
gene id: 1109412:AWC36_RS20190
uniprot id: A0A0G4JU09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS12625
gene id: 1109412:AWC36_RS12625
uniprot id: A0A0G4JPC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

1109412:AWC36 RS05340
gene id: 1109412:AWC36_RS05340
uniprot id: A0A0G4JZ68
names: Similarity
messages: Belongs to the UPF0352 family.

1109412:AWC36 RS10540
gene id: 1109412:AWC36_RS10540
uniprot id: A0A0G4K2F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS20125
gene id: 1109412:AWC36_RS20125
uniprot id: A0A0G4JTZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

1109412:AWC36 RS16990
gene id: 1109412:AWC36_RS16990
uniprot id: A0A0G4JS28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SIS family. DiaA subfamily.
messages: Homotetramer; dimer of dimers.
messages: Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.

1109412:AWC36 RS17580
gene id: 1109412:AWC36_RS17580
uniprot id: A0A0G4JSD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NusG family.
messages: Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
messages: Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.

1109412:AWC36 RS19365
gene id: 1109412:AWC36_RS19365
uniprot id: A0A0G4JTK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1109412:AWC36 RS13220
gene id: 1109412:AWC36_RS13220
uniprot id: A0A0G4JPR9
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1109412:AWC36 RS02775
gene id: 1109412:AWC36_RS02775
uniprot id: A0A0G4JXI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1109412:AWC36 RS18765
gene id: 1109412:AWC36_RS18765
uniprot id: A0A0G4JTS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1109412:AWC36 RS11945
gene id: 1109412:AWC36_RS11945
uniprot id: A0A0G4JP22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1109412:AWC36 RS05425
gene id: 1109412:AWC36_RS05425
uniprot id: A0A0G4JZA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HspQ family.
messages: Cytoplasm
messages: Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.

1109412:AWC36 RS00990
gene id: 1109412:AWC36_RS00990
uniprot id: A0A0G4JWF2
names: Function
names: Similarity
messages: Belongs to the ETF-QO/FixC family.
messages: Part of an electron transfer system.

1109412:AWC36 RS05900
gene id: 1109412:AWC36_RS05900
uniprot id: A0A0G4JZ89
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1109412:AWC36 RS01905
gene id: 1109412:AWC36_RS01905
uniprot id: A0A0G4JWS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1109412:AWC36 RS01610
gene id: 1109412:AWC36_RS01610
uniprot id: A0A0G4JX79
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1109412:AWC36 RS16660
gene id: 1109412:AWC36_RS16660
uniprot id: A0A250BHD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1109412:AWC36 RS03100
gene id: 1109412:AWC36_RS03100
uniprot id: A0A0G4JXT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1109412:AWC36 RS03630
gene id: 1109412:AWC36_RS03630
uniprot id: A0A0G4JXV4
names: Function
names: Similarity
messages: Belongs to the IolE/MocC family.
messages: Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).

1109412:AWC36 RS11595
gene id: 1109412:AWC36_RS11595
uniprot id: A0A0G4K2X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1109412:AWC36 RS21425
gene id: 1109412:AWC36_RS21425
uniprot id: A0A0G4JUN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1109412:AWC36 RS19665
gene id: 1109412:AWC36_RS19665
uniprot id: A0A0G4JTM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1109412:AWC36 RS20380
gene id: 1109412:AWC36_RS20380
uniprot id: A0A0G4JU34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS23235
gene id: 1109412:AWC36_RS23235
uniprot id: A0A250BKQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlaE exporter family.
messages: Cell inner membrane
messages: Exports L-alanine.

1109412:AWC36 RS12640
gene id: 1109412:AWC36_RS12640
uniprot id: A0A0G4JPE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1109412:AWC36 RS05380
gene id: 1109412:AWC36_RS05380
uniprot id: A0A0G4JYZ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer and homodimer.
messages: The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins.
messages: With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.

1109412:AWC36 RS20340
gene id: 1109412:AWC36_RS20340
uniprot id: A0A0G4JU13
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS17550
gene id: 1109412:AWC36_RS17550
uniprot id: A0A0G4JSF6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1109412:AWC36 RS00945
gene id: 1109412:AWC36_RS00945
uniprot id: A0A0G4JWE3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS19350
gene id: 1109412:AWC36_RS19350
uniprot id: A0A0G4JTG4
names: Subcellular Location Annotation
messages: Cytoplasm

1109412:AWC36 RS00395
gene id: 1109412:AWC36_RS00395
uniprot id: A0A0G4JW20
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1109412:AWC36 RS12115
gene id: 1109412:AWC36_RS12115
uniprot id: A0A250BFT5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1109412:AWC36 RS22335
gene id: 1109412:AWC36_RS22335
uniprot id: A0A0G4JV54
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS13450
gene id: 1109412:AWC36_RS13450
uniprot id: A0A0G4JQC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS22495
gene id: 1109412:AWC36_RS22495
uniprot id: A0A0G4JV65
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1109412:AWC36 RS20750
gene id: 1109412:AWC36_RS20750
uniprot id: A0A250BK54
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Homotetramer.
messages: Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel.

1109412:AWC36 RS02210
gene id: 1109412:AWC36_RS02210
uniprot id: A0A0G4JWZ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1109412:AWC36 RS07900
gene id: 1109412:AWC36_RS07900
uniprot id: A0A0G4K0I6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1109412:AWC36 RS21735
gene id: 1109412:AWC36_RS21735
uniprot id: A0A0G4JUW7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1109412:AWC36 RS09735
gene id: 1109412:AWC36_RS09735
uniprot id: A0A0G4K1Z3
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1109412:AWC36 RS15245
gene id: 1109412:AWC36_RS15245
uniprot id: A0A0G4JR16
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1109412:AWC36 RS02160
gene id: 1109412:AWC36_RS02160
uniprot id: A0A0G4JWX0
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1109412:AWC36 RS22845
gene id: 1109412:AWC36_RS22845
uniprot id: A0A0G4JVI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1109412:AWC36 RS22480
gene id: 1109412:AWC36_RS22480
uniprot id: A0A0G4JVU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS06730
gene id: 1109412:AWC36_RS06730
uniprot id: A0A0G4K002
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS03240
gene id: 1109412:AWC36_RS03240
uniprot id: A0A0G4JYE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

1109412:AWC36 RS01025
gene id: 1109412:AWC36_RS01025
uniprot id: A0A0G4JWD7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

1109412:AWC36 RS06700
gene id: 1109412:AWC36_RS06700
uniprot id: A0A0G4JZZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

1109412:AWC36 RS02755
gene id: 1109412:AWC36_RS02755
uniprot id: A0A0G4JXE5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1109412:AWC36 RS20215
gene id: 1109412:AWC36_RS20215
uniprot id: A0A250BM00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

1109412:AWC36 RS07665
gene id: 1109412:AWC36_RS07665
uniprot id: A0A0G4K149
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1109412:AWC36 RS15410
gene id: 1109412:AWC36_RS15410
uniprot id: A0A0G4JR55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1109412:AWC36 RS20130
gene id: 1109412:AWC36_RS20130
uniprot id: A0A0G4JU22
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1109412:AWC36 RS02960
gene id: 1109412:AWC36_RS02960
uniprot id: A0A0G4JXQ5
names: Similarity
messages: Belongs to the MlaA family.

1109412:AWC36 RS02145
gene id: 1109412:AWC36_RS02145
uniprot id: A0A0G4JX08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 2 iron ions per dimer. The dimer may bind additional iron ions.
messages: Homodimer; may form tetramers and higher multimers.
messages: Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.

1109412:AWC36 RS21995
gene id: 1109412:AWC36_RS21995
uniprot id: A0A0G4JV34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1109412:AWC36 RS15820
gene id: 1109412:AWC36_RS15820
uniprot id: A0A0G4JRD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1109412:AWC36 RS07520
gene id: 1109412:AWC36_RS07520
uniprot id: A0A0G4K117
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1109412:AWC36 RS19345
gene id: 1109412:AWC36_RS19345
uniprot id: A0A0G4JTK0
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS03255
gene id: 1109412:AWC36_RS03255
uniprot id: A0A0G4JXN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1109412:AWC36 RS12745
gene id: 1109412:AWC36_RS12745
uniprot id: A0A250BFK7
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

1109412:AWC36 RS10920
gene id: 1109412:AWC36_RS10920
uniprot id: A0A0G4K2E5
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS08420
gene id: 1109412:AWC36_RS08420
uniprot id: A0A250BCZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1109412:AWC36 RS00250
gene id: 1109412:AWC36_RS00250
uniprot id: A0A0G4JWM2
names: Similarity
messages: Belongs to the GSP E family.

1109412:AWC36 RS23300
gene id: 1109412:AWC36_RS23300
uniprot id: A0A0G4JVI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1109412:AWC36 RS04860
gene id: 1109412:AWC36_RS04860
uniprot id: A0A0G4JZ34
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

1109412:AWC36 RS15800
gene id: 1109412:AWC36_RS15800
uniprot id: A0A0G4JRC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1109412:AWC36 RS04960
gene id: 1109412:AWC36_RS04960
uniprot id: A0A0G4JZQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS17825
gene id: 1109412:AWC36_RS17825
uniprot id: A0A250BHZ8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

1109412:AWC36 RS00980
gene id: 1109412:AWC36_RS00980
uniprot id: A0A0G4JX27
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1109412:AWC36 RS21600
gene id: 1109412:AWC36_RS21600
uniprot id: A0A0G4JUX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1109412:AWC36 RS14325
gene id: 1109412:AWC36_RS14325
uniprot id: A0A0G4JR42
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS09690
gene id: 1109412:AWC36_RS09690
uniprot id: A0A0G4K1M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1109412:AWC36 RS13130
gene id: 1109412:AWC36_RS13130
uniprot id: A0A0G4JQ54
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1109412:AWC36 RS06690
gene id: 1109412:AWC36_RS06690
uniprot id: A0A0G4K0D9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1109412:AWC36 RS15930
gene id: 1109412:AWC36_RS15930
uniprot id: A0A0G4JRF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MzrA family.
messages: Cell inner membrane
messages: Interacts with EnvZ.
messages: Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.

1109412:AWC36 RS20295
gene id: 1109412:AWC36_RS20295
uniprot id: A0A0G4JUJ9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1109412:AWC36 RS14435
gene id: 1109412:AWC36_RS14435
uniprot id: A0A0G4JQJ9
names: Subcellular Location Annotation
messages: Cytoplasm

1109412:AWC36 RS21015
gene id: 1109412:AWC36_RS21015
uniprot id: A0A250BLH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

1109412:AWC36 RS13020
gene id: 1109412:AWC36_RS13020
uniprot id: A0A0G4JPQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1109412:AWC36 RS13640
gene id: 1109412:AWC36_RS13640
uniprot id: A0A0G4JQ31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1109412:AWC36 RS16385
gene id: 1109412:AWC36_RS16385
uniprot id: A0A250BLB6
names: Similarity
messages: Belongs to the UPF0149 family.

1109412:AWC36 RS21265
gene id: 1109412:AWC36_RS21265
uniprot id: A0A0G4JUK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS23380
gene id: 1109412:AWC36_RS23380
uniprot id: A0A0G4JVL7
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1109412:AWC36 RS10940
gene id: 1109412:AWC36_RS10940
uniprot id: A0A0G4K324
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS09075
gene id: 1109412:AWC36_RS09075
uniprot id: A0A0G4K1H2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1109412:AWC36 RS07610
gene id: 1109412:AWC36_RS07610
uniprot id: A0A0G4K0K4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1109412:AWC36 RS09425
gene id: 1109412:AWC36_RS09425
uniprot id: A0A0G4K1T5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1109412:AWC36 RS09570
gene id: 1109412:AWC36_RS09570
uniprot id: A0A0G4K1W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1109412:AWC36 RS01095
gene id: 1109412:AWC36_RS01095
uniprot id: A0A250B9Q8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Crl family.
messages: Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS22895
gene id: 1109412:AWC36_RS22895
uniprot id: A0A250BKC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1109412:AWC36 RS21760
gene id: 1109412:AWC36_RS21760
uniprot id: A0A0G4JUX2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).

1109412:AWC36 RS21250
gene id: 1109412:AWC36_RS21250
uniprot id: A0A0G4JUN6
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1109412:AWC36 RS13330
gene id: 1109412:AWC36_RS13330
uniprot id: A0A0G4JPS6
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1109412:AWC36 RS08275
gene id: 1109412:AWC36_RS08275
uniprot id: A0A0G4K0M7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

1109412:AWC36 RS22470
gene id: 1109412:AWC36_RS22470
uniprot id: A0A0G4JV61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1109412:AWC36 RS03175
gene id: 1109412:AWC36_RS03175
uniprot id: A0A0G4JXR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1109412:AWC36 RS08360
gene id: 1109412:AWC36_RS08360
uniprot id: A0A0G4K0Y0
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1109412:AWC36 RS11160
gene id: 1109412:AWC36_RS11160
uniprot id: A0A0G4K2R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1109412:AWC36 RS09560
gene id: 1109412:AWC36_RS09560
uniprot id: A0A0G4K1M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS00410
gene id: 1109412:AWC36_RS00410
uniprot id: A0A0G4JWR0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1109412:AWC36 RS12180
gene id: 1109412:AWC36_RS12180
uniprot id: A0A0G4JP62
names: Similarity
messages: Belongs to the citrate synthase family.

1109412:AWC36 RS01840
gene id: 1109412:AWC36_RS01840
uniprot id: A0A0G4JWU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1109412:AWC36 RS19140
gene id: 1109412:AWC36_RS19140
uniprot id: A0A0G4JTG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1109412:AWC36 RS06695
gene id: 1109412:AWC36_RS06695
uniprot id: A0A0G4JZT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1109412:AWC36 RS09795
gene id: 1109412:AWC36_RS09795
uniprot id: A0A0G4K1R9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.

1109412:AWC36 RS13160
gene id: 1109412:AWC36_RS13160
uniprot id: A0A250BFA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1109412:AWC36 RS12750
gene id: 1109412:AWC36_RS12750
uniprot id: A0A250BFK3
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS15525
gene id: 1109412:AWC36_RS15525
uniprot id: A0A0G4JR75
names: Similarity
messages: Belongs to the FrmR/RcnR family.

1109412:AWC36 RS11980
gene id: 1109412:AWC36_RS11980
uniprot id: A0A0G4JPP0
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1109412:AWC36 RS16955
gene id: 1109412:AWC36_RS16955
uniprot id: A0A0G4JS48
names: Similarity
messages: Belongs to the UPF0441 family.

1109412:AWC36 RS02620
gene id: 1109412:AWC36_RS02620
uniprot id: A0A0G4JX88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS16460
gene id: 1109412:AWC36_RS16460
uniprot id: A0A0G4JRV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS17075
gene id: 1109412:AWC36_RS17075
uniprot id: A0A0G4JS39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS15965
gene id: 1109412:AWC36_RS15965
uniprot id: A0A0G4JRF9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS00815
gene id: 1109412:AWC36_RS00815
uniprot id: A0A0G4JWZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1109412:AWC36 RS04645
gene id: 1109412:AWC36_RS04645
uniprot id: A0A0G4JZ18
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS00775
gene id: 1109412:AWC36_RS00775
uniprot id: A0A0G4JWB7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

1109412:AWC36 RS18190
gene id: 1109412:AWC36_RS18190
uniprot id: A0A0G4JTC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

1109412:AWC36 RS14535
gene id: 1109412:AWC36_RS14535
uniprot id: A0A0G4JQM0
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.

1109412:AWC36 RS15040
gene id: 1109412:AWC36_RS15040
uniprot id: A0A0G4JQX7
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS22870
gene id: 1109412:AWC36_RS22870
uniprot id: A0A0G4JVJ2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1109412:AWC36 RS19580
gene id: 1109412:AWC36_RS19580
uniprot id: A0A0G4JTP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS12535
gene id: 1109412:AWC36_RS12535
uniprot id: A0A250BFG4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1109412:AWC36 RS01515
gene id: 1109412:AWC36_RS01515
uniprot id: A0A250B9U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1109412:AWC36 RS03265
gene id: 1109412:AWC36_RS03265
uniprot id: A0A0G4JXQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1109412:AWC36 RS14430
gene id: 1109412:AWC36_RS14430
uniprot id: A0A0G4JQN3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1109412:AWC36 RS00865
gene id: 1109412:AWC36_RS00865
uniprot id: A0A0G4JWZ9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.

1109412:AWC36 RS15475
gene id: 1109412:AWC36_RS15475
uniprot id: A0A250BGT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1109412:AWC36 RS18715
gene id: 1109412:AWC36_RS18715
uniprot id: A0A0G4JTR6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS15590
gene id: 1109412:AWC36_RS15590
uniprot id: A0A0G4JR83
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS02780
gene id: 1109412:AWC36_RS02780
uniprot id: A0A0G4JXB3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1109412:AWC36 RS23550
gene id: 1109412:AWC36_RS23550
uniprot id: A0A0G4JVS6
names: Similarity
messages: Belongs to the DapA family.

1109412:AWC36 RS23095
gene id: 1109412:AWC36_RS23095
uniprot id: A0A0G4JVE1
names: Similarity
messages: Belongs to the class-I fumarase family.

1109412:AWC36 RS13685
gene id: 1109412:AWC36_RS13685
uniprot id: A0A0G4JQ05
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS01845
gene id: 1109412:AWC36_RS01845
uniprot id: A0A0G4JWN0
names: Function
messages: Acts as a radical domain for damaged PFL and possibly other radical proteins.

1109412:AWC36 RS19450
gene id: 1109412:AWC36_RS19450
uniprot id: A0A0G4JTL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS13230
gene id: 1109412:AWC36_RS13230
uniprot id: A0A0G4JPQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS01660
gene id: 1109412:AWC36_RS01660
uniprot id: A0A250BLU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

1109412:AWC36 RS05655
gene id: 1109412:AWC36_RS05655
uniprot id: A0A0G4JZ40
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1109412:AWC36 RS20610
gene id: 1109412:AWC36_RS20610
uniprot id: A0A0G4JU62
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

1109412:AWC36 RS14640
gene id: 1109412:AWC36_RS14640
uniprot id: A0A0G4JQR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS08340
gene id: 1109412:AWC36_RS08340
uniprot id: A0A0G4K0Z0
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1109412:AWC36 RS09780
gene id: 1109412:AWC36_RS09780
uniprot id: A0A0G4K203
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1109412:AWC36 RS01015
gene id: 1109412:AWC36_RS01015
uniprot id: A0A0G4JWF6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

1109412:AWC36 RS15975
gene id: 1109412:AWC36_RS15975
uniprot id: A0A0G4JRG2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1109412:AWC36 RS07915
gene id: 1109412:AWC36_RS07915
uniprot id: A0A0G4K0E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1109412:AWC36 RS09265
gene id: 1109412:AWC36_RS09265
uniprot id: A0A0G4K1Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1109412:AWC36 RS15750
gene id: 1109412:AWC36_RS15750
uniprot id: A0A0G4JRE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1109412:AWC36 RS19880
gene id: 1109412:AWC36_RS19880
uniprot id: A0A0G4JTR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS10715
gene id: 1109412:AWC36_RS10715
uniprot id: A0A0G4K2K1
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS08745
gene id: 1109412:AWC36_RS08745
uniprot id: A0A0G4K183
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism.

1109412:AWC36 RS15885
gene id: 1109412:AWC36_RS15885
uniprot id: A0A0G4JRZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1109412:AWC36 RS13880
gene id: 1109412:AWC36_RS13880
uniprot id: A0A0G4JQ62
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1109412:AWC36 RS12500
gene id: 1109412:AWC36_RS12500
uniprot id: A0A0G4JPC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1109412:AWC36 RS12630
gene id: 1109412:AWC36_RS12630
uniprot id: A0A0G4JPG5
names: Similarity
messages: Belongs to the ArsC family.

1109412:AWC36 RS19270
gene id: 1109412:AWC36_RS19270
uniprot id: A0A0G4JTF3
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS17785
gene id: 1109412:AWC36_RS17785
uniprot id: A0A0G4JSG0
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1109412:AWC36 RS00260
gene id: 1109412:AWC36_RS00260
uniprot id: A0A0G4JVY9
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS05435
gene id: 1109412:AWC36_RS05435
uniprot id: A0A250BBG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Interacts with the TusBCD complex. Interacts with MnmA.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD.

1109412:AWC36 RS01425
gene id: 1109412:AWC36_RS01425
uniprot id: A0A0G4JX66
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1109412:AWC36 RS21140
gene id: 1109412:AWC36_RS21140
uniprot id: A0A0G4JUL1
names: Similarity
messages: Belongs to the HSP15 family.

1109412:AWC36 RS08170
gene id: 1109412:AWC36_RS08170
uniprot id: A0A0G4K0V7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS20850
gene id: 1109412:AWC36_RS20850
uniprot id: A0A0G4JUD4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1109412:AWC36 RS20820
gene id: 1109412:AWC36_RS20820
uniprot id: A0A0G4JUC3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS20465
gene id: 1109412:AWC36_RS20465
uniprot id: A0A0G4JU35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
messages: Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.
messages: Cytoplasm
messages: Homodimer.

1109412:AWC36 RS19150
gene id: 1109412:AWC36_RS19150
uniprot id: A0A0G4JTC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1109412:AWC36 RS04680
gene id: 1109412:AWC36_RS04680
uniprot id: A0A0G4JYW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1109412:AWC36 RS13105
gene id: 1109412:AWC36_RS13105
uniprot id: A0A250BFI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS17860
gene id: 1109412:AWC36_RS17860
uniprot id: A0A0G4JT45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1109412:AWC36 RS08245
gene id: 1109412:AWC36_RS08245
uniprot id: A0A0G4K0V6
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

1109412:AWC36 RS16310
gene id: 1109412:AWC36_RS16310
uniprot id: A0A0G4JRP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

1109412:AWC36 RS18070
gene id: 1109412:AWC36_RS18070
uniprot id: A0A0G4JT95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH2/MDH2 oxidoreductase family. DlgD subfamily.
messages: Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.
messages: Cytoplasm
messages: Homodimer.

1109412:AWC36 RS17620
gene id: 1109412:AWC36_RS17620
uniprot id: A0A0G4JSC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1109412:AWC36 RS12140
gene id: 1109412:AWC36_RS12140
uniprot id: A0A0G4JPR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1109412:AWC36 RS06630
gene id: 1109412:AWC36_RS06630
uniprot id: A0A0G4JZX7
names: Similarity
messages: Belongs to the CFA/CMAS family.

1109412:AWC36 RS08180
gene id: 1109412:AWC36_RS08180
uniprot id: A0A0G4K1E4
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1109412:AWC36 RS18600
gene id: 1109412:AWC36_RS18600
uniprot id: A0A250BIE8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1109412:AWC36 RS07240
gene id: 1109412:AWC36_RS07240
uniprot id: A0A0G4K068
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1109412:AWC36 RS08575
gene id: 1109412:AWC36_RS08575
uniprot id: A0A0G4K0W3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1109412:AWC36 RS03565
gene id: 1109412:AWC36_RS03565
uniprot id: A0A0G4JXU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS22945
gene id: 1109412:AWC36_RS22945
uniprot id: A0A0G4JVC2
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1109412:AWC36 RS18120
gene id: 1109412:AWC36_RS18120
uniprot id: A0A0G4JTA9
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS01900
gene id: 1109412:AWC36_RS01900
uniprot id: A0A250BA03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1109412:AWC36 RS12295
gene id: 1109412:AWC36_RS12295
uniprot id: A0A0G4JPA3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1109412:AWC36 RS12770
gene id: 1109412:AWC36_RS12770
uniprot id: A0A0G4JPG3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1109412:AWC36 RS14865
gene id: 1109412:AWC36_RS14865
uniprot id: A0A250BLS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS10165
gene id: 1109412:AWC36_RS10165
uniprot id: A0A0G4K1Z4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

1109412:AWC36 RS02575
gene id: 1109412:AWC36_RS02575
uniprot id: A0A0G4JX84
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
messages: Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably phosphorylates lipids; the in vivo substrate is unknown.

1109412:AWC36 RS08080
gene id: 1109412:AWC36_RS08080
uniprot id: A0A0G4K0T8
names: Similarity
messages: Belongs to the YciI family.

1109412:AWC36 RS01680
gene id: 1109412:AWC36_RS01680
uniprot id: A0A250BAE6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1109412:AWC36 RS03180
gene id: 1109412:AWC36_RS03180
uniprot id: A0A0G4JXU6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1109412:AWC36 RS15815
gene id: 1109412:AWC36_RS15815
uniprot id: A0A250BH02
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1109412:AWC36 RS16870
gene id: 1109412:AWC36_RS16870
uniprot id: A0A0G4JSQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS20580
gene id: 1109412:AWC36_RS20580
uniprot id: A0A0G4JUA0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1109412:AWC36 RS23010
gene id: 1109412:AWC36_RS23010
uniprot id: A0A0G4JVL1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS03185
gene id: 1109412:AWC36_RS03185
uniprot id: A0A0G4JXL7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1109412:AWC36 RS20735
gene id: 1109412:AWC36_RS20735
uniprot id: A0A0G4JUU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS09180
gene id: 1109412:AWC36_RS09180
uniprot id: A0A0G4K1D1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1109412:AWC36 RS13165
gene id: 1109412:AWC36_RS13165
uniprot id: A0A0G4JPP7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1109412:AWC36 RS07770
gene id: 1109412:AWC36_RS07770
uniprot id: A0A0G4K0B7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1109412:AWC36 RS15635
gene id: 1109412:AWC36_RS15635
uniprot id: A0A0G4JRC7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1109412:AWC36 RS21380
gene id: 1109412:AWC36_RS21380
uniprot id: A0A0G4JUR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1109412:AWC36 RS12650
gene id: 1109412:AWC36_RS12650
uniprot id: A0A0G4JPD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1109412:AWC36 RS01710
gene id: 1109412:AWC36_RS01710
uniprot id: A0A0G4JWN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1109412:AWC36 RS00345
gene id: 1109412:AWC36_RS00345
uniprot id: A0A0G4JW33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm
messages: Monomer.

1109412:AWC36 RS15110
gene id: 1109412:AWC36_RS15110
uniprot id: A0A0G4JRI8
names: Subcellular Location Annotation
messages: Cytoplasm

1109412:AWC36 RS21445
gene id: 1109412:AWC36_RS21445
uniprot id: A0A0G4JUR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1109412:AWC36 RS05725
gene id: 1109412:AWC36_RS05725
uniprot id: A0A0G4JZE9
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1109412:AWC36 RS17800
gene id: 1109412:AWC36_RS17800
uniprot id: A0A0G4JSK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1109412:AWC36 RS10855
gene id: 1109412:AWC36_RS10855
uniprot id: A0A250BL98
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS01050
gene id: 1109412:AWC36_RS01050
uniprot id: A0A0G4JWG1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1109412:AWC36 RS21770
gene id: 1109412:AWC36_RS21770
uniprot id: A0A0G4JV03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1109412:AWC36 RS09110
gene id: 1109412:AWC36_RS09110
uniprot id: A0A250BDP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS18875
gene id: 1109412:AWC36_RS18875
uniprot id: A0A0G4JT63
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS17255
gene id: 1109412:AWC36_RS17255
uniprot id: A0A0G4JS79
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1109412:AWC36 RS13695
gene id: 1109412:AWC36_RS13695
uniprot id: A0A250BG23
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1109412:AWC36 RS20245
gene id: 1109412:AWC36_RS20245
uniprot id: A0A0G4JU45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Belongs to the flavodoxin family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell membrane

1109412:AWC36 RS13170
gene id: 1109412:AWC36_RS13170
uniprot id: A0A0G4JPQ6
names: Similarity
messages: Belongs to the BolA/IbaG family.

1109412:AWC36 RS09440
gene id: 1109412:AWC36_RS09440
uniprot id: A0A0G4K1L0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS21205
gene id: 1109412:AWC36_RS21205
uniprot id: A0A0G4JV89
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1109412:AWC36 RS12170
gene id: 1109412:AWC36_RS12170
uniprot id: A0A0G4JP55
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: The heme is bound between the two transmembrane subunits.

1109412:AWC36 RS07925
gene id: 1109412:AWC36_RS07925
uniprot id: A0A0G4K0J1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1109412:AWC36 RS01760
gene id: 1109412:AWC36_RS01760
uniprot id: A0A0G4JWT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BtuF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

1109412:AWC36 RS11960
gene id: 1109412:AWC36_RS11960
uniprot id: A0A0G4JP17
names: Function
names: Similarity
messages: Belongs to the cycloisomerase 2 family.
messages: Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1109412:AWC36 RS22960
gene id: 1109412:AWC36_RS22960
uniprot id: A0A0G4JVK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1109412:AWC36 RS05645
gene id: 1109412:AWC36_RS05645
uniprot id: A0A0G4JZB7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1109412:AWC36 RS04975
gene id: 1109412:AWC36_RS04975
uniprot id: A0A0G4JZ84
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS23255
gene id: 1109412:AWC36_RS23255
uniprot id: A0A0G4JVJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

1109412:AWC36 RS02165
gene id: 1109412:AWC36_RS02165
uniprot id: A0A0G4JWY1
names: Function
names: Similarity
messages: Belongs to the IscX family.
messages: May function as iron donor in the assembly of iron-sulfur clusters.

1109412:AWC36 RS22510
gene id: 1109412:AWC36_RS22510
uniprot id: A0A0G4JVF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
messages: Cell membrane
messages: Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine.
messages: Membrane

1109412:AWC36 RS12540
gene id: 1109412:AWC36_RS12540
uniprot id: A0A250BFD3
names: Subcellular Location Annotation
messages: Cytoplasm

1109412:AWC36 RS07280
gene id: 1109412:AWC36_RS07280
uniprot id: A0A250BCQ3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1109412:AWC36 RS15650
gene id: 1109412:AWC36_RS15650
uniprot id: A0A0G4JRU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1109412:AWC36 RS20410
gene id: 1109412:AWC36_RS20410
uniprot id: A0A250BJF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1109412:AWC36 RS06115
gene id: 1109412:AWC36_RS06115
uniprot id: A0A0G4JZL8
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS13200
gene id: 1109412:AWC36_RS13200
uniprot id: A0A0G4JQ67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1109412:AWC36 RS01035
gene id: 1109412:AWC36_RS01035
uniprot id: A0A0G4JWF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
messages: Homodimer.

1109412:AWC36 RS05625
gene id: 1109412:AWC36_RS05625
uniprot id: A0A0G4JZD1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1109412:AWC36 RS01105
gene id: 1109412:AWC36_RS01105
uniprot id: A0A0G4JWG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1109412:AWC36 RS14975
gene id: 1109412:AWC36_RS14975
uniprot id: A0A250BG79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell inner membrane
messages: Membrane
messages: Transports acetate.

1109412:AWC36 RS14660
gene id: 1109412:AWC36_RS14660
uniprot id: A0A0G4JQP0
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1109412:AWC36 RS13740
gene id: 1109412:AWC36_RS13740
uniprot id: A0A0G4JQ18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1109412:AWC36 RS12730
gene id: 1109412:AWC36_RS12730
uniprot id: A0A0G4JQ20
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS03935
gene id: 1109412:AWC36_RS03935
uniprot id: A0A0G4JY18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1109412:AWC36 RS21405
gene id: 1109412:AWC36_RS21405
uniprot id: A0A0G4JUR5
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1109412:AWC36 RS15790
gene id: 1109412:AWC36_RS15790
uniprot id: A0A0G4JRC4
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

1109412:AWC36 RS09575
gene id: 1109412:AWC36_RS09575
uniprot id: A0A0G4K1L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS21315
gene id: 1109412:AWC36_RS21315
uniprot id: A0A0G4JUL0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1109412:AWC36 RS18905
gene id: 1109412:AWC36_RS18905
uniprot id: A0A250BLX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS00820
gene id: 1109412:AWC36_RS00820
uniprot id: A0A0G4JWC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS14300
gene id: 1109412:AWC36_RS14300
uniprot id: A0A250BFX9
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS09580
gene id: 1109412:AWC36_RS09580
uniprot id: A0A0G4K2D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

1109412:AWC36 RS19325
gene id: 1109412:AWC36_RS19325
uniprot id: A0A0G4JTJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations.

1109412:AWC36 RS18425
gene id: 1109412:AWC36_RS18425
uniprot id: A0A0G4JSU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1109412:AWC36 RS05545
gene id: 1109412:AWC36_RS05545
uniprot id: A0A250BKV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0312 family. Type 1 subfamily.
messages: Periplasm

1109412:AWC36 RS02110
gene id: 1109412:AWC36_RS02110
uniprot id: A0A250BA45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1109412:AWC36 RS11975
gene id: 1109412:AWC36_RS11975
uniprot id: A0A0G4JP35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1109412:AWC36 RS12725
gene id: 1109412:AWC36_RS12725
uniprot id: A0A0G4JPG2
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1109412:AWC36 RS18025
gene id: 1109412:AWC36_RS18025
uniprot id: A0A0G4JSQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1109412:AWC36 RS07635
gene id: 1109412:AWC36_RS07635
uniprot id: A0A0G4K088
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

1109412:AWC36 RS05690
gene id: 1109412:AWC36_RS05690
uniprot id: A0A250BL38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1109412:AWC36 RS14330
gene id: 1109412:AWC36_RS14330
uniprot id: A0A0G4JQI0
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1109412:AWC36 RS17880
gene id: 1109412:AWC36_RS17880
uniprot id: A0A0G4JSJ4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1109412:AWC36 RS11100
gene id: 1109412:AWC36_RS11100
uniprot id: A0A250BEQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1109412:AWC36 RS02100
gene id: 1109412:AWC36_RS02100
uniprot id: A0A0G4JWT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

1109412:AWC36 RS07800
gene id: 1109412:AWC36_RS07800
uniprot id: A0A0G4K0G6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS02785
gene id: 1109412:AWC36_RS02785
uniprot id: A0A0G4JXD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1109412:AWC36 RS00405
gene id: 1109412:AWC36_RS00405
uniprot id: A0A0G4JW19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1109412:AWC36 RS22865
gene id: 1109412:AWC36_RS22865
uniprot id: A0A250BK56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1109412:AWC36 RS09360
gene id: 1109412:AWC36_RS09360
uniprot id: A0A0G4K297
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1109412:AWC36 RS18590
gene id: 1109412:AWC36_RS18590
uniprot id: A0A0G4JSZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1109412:AWC36 RS08400
gene id: 1109412:AWC36_RS08400
uniprot id: A0A0G4K0T2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

1109412:AWC36 RS21650
gene id: 1109412:AWC36_RS21650
uniprot id: A0A0G4JUU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1109412:AWC36 RS23285
gene id: 1109412:AWC36_RS23285
uniprot id: A0A0G4JW83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1109412:AWC36 RS08305
gene id: 1109412:AWC36_RS08305
uniprot id: A0A0G4K0R5
names: Similarity
messages: Belongs to the UPF0260 family.

1109412:AWC36 RS04595
gene id: 1109412:AWC36_RS04595
uniprot id: A0A0G4JYY4
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1109412:AWC36 RS08405
gene id: 1109412:AWC36_RS08405
uniprot id: A0A0G4K0Z1
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS15795
gene id: 1109412:AWC36_RS15795
uniprot id: A0A0G4JRX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

1109412:AWC36 RS03025
gene id: 1109412:AWC36_RS03025
uniprot id: A0A0G4JXS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS05470
gene id: 1109412:AWC36_RS05470
uniprot id: A0A0G4JZ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1109412:AWC36 RS22420
gene id: 1109412:AWC36_RS22420
uniprot id: A0A250BKZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1109412:AWC36 RS16005
gene id: 1109412:AWC36_RS16005
uniprot id: A0A0G4JS27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1109412:AWC36 RS09565
gene id: 1109412:AWC36_RS09565
uniprot id: A0A0G4K1S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

1109412:AWC36 RS08160
gene id: 1109412:AWC36_RS08160
uniprot id: A0A0G4K0N8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1109412:AWC36 RS16185
gene id: 1109412:AWC36_RS16185
uniprot id: A0A0G4JRL8
names: Subcellular Location Annotation
messages: Cell inner membrane

1109412:AWC36 RS06855
gene id: 1109412:AWC36_RS06855
uniprot id: A0A0G4K012
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS06120
gene id: 1109412:AWC36_RS06120
uniprot id: A0A0G4JZN7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1109412:AWC36 RS00660
gene id: 1109412:AWC36_RS00660
uniprot id: A0A0G4JW65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1109412:AWC36 RS23185
gene id: 1109412:AWC36_RS23185
uniprot id: A0A0G4JVI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1109412:AWC36 RS12395
gene id: 1109412:AWC36_RS12395
uniprot id: A0A0G4JPB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS09895
gene id: 1109412:AWC36_RS09895
uniprot id: A0A0G4K1R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

1109412:AWC36 RS00170
gene id: 1109412:AWC36_RS00170
uniprot id: A0A0G4JVW5
names: Function
names: Similarity
messages: Belongs to the ETF-QO/FixC family.
messages: Part of an electron transfer system.

1109412:AWC36 RS17760
gene id: 1109412:AWC36_RS17760
uniprot id: A0A0G4JSJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1109412:AWC36 RS00525
gene id: 1109412:AWC36_RS00525
uniprot id: A0A0G4JWT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1109412:AWC36 RS07465
gene id: 1109412:AWC36_RS07465
uniprot id: A0A250BCT2
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

1109412:AWC36 RS09730
gene id: 1109412:AWC36_RS09730
uniprot id: A0A0G4K1W5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1109412:AWC36 RS03145
gene id: 1109412:AWC36_RS03145
uniprot id: A0A0G4JXN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1109412:AWC36 RS08375
gene id: 1109412:AWC36_RS08375
uniprot id: A0A0G4K1G6
names: Similarity
messages: Belongs to the UPF0181 family.

1109412:AWC36 RS08270
gene id: 1109412:AWC36_RS08270
uniprot id: A0A0G4K0X8
names: Similarity
messages: Belongs to the UPF0229 family.

1109412:AWC36 RS06625
gene id: 1109412:AWC36_RS06625
uniprot id: A0A0G4JZR8
names: Function
messages: Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.

1109412:AWC36 RS15265
gene id: 1109412:AWC36_RS15265
uniprot id: A0A0G4JR57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS05660
gene id: 1109412:AWC36_RS05660
uniprot id: A0A0G4JZX5
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS00960
gene id: 1109412:AWC36_RS00960
uniprot id: A0A0G4JX22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.

1109412:AWC36 RS17250
gene id: 1109412:AWC36_RS17250
uniprot id: A0A0G4JS70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1109412:AWC36 RS10605
gene id: 1109412:AWC36_RS10605
uniprot id: A0A0G4K278
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS07565
gene id: 1109412:AWC36_RS07565
uniprot id: A0A0G4K128
names: Function
names: Subunit
messages: Interacts with sigma-54.
messages: Required for activation of most nif operons, which are directly involved in nitrogen fixation.

1109412:AWC36 RS02770
gene id: 1109412:AWC36_RS02770
uniprot id: A0A0G4JXC7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1109412:AWC36 RS05440
gene id: 1109412:AWC36_RS05440
uniprot id: A0A0G4JZ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1109412:AWC36 RS13355
gene id: 1109412:AWC36_RS13355
uniprot id: A0A0G4JPT1
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

1109412:AWC36 RS20315
gene id: 1109412:AWC36_RS20315
uniprot id: A0A0G4JU08
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1109412:AWC36 RS08540
gene id: 1109412:AWC36_RS08540
uniprot id: A0A0G4K0R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1109412:AWC36 RS12760
gene id: 1109412:AWC36_RS12760
uniprot id: A0A0G4JPF6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RcsB family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
messages: Interacts with RcsD.
messages: Phosphorylated and activated by RcsD.

1109412:AWC36 RS05695
gene id: 1109412:AWC36_RS05695
uniprot id: A0A0G4JZC4
names: Similarity
messages: Belongs to the UPF0227 family.

1109412:AWC36 RS14495
gene id: 1109412:AWC36_RS14495
uniprot id: A0A0G4JQP5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1109412:AWC36 RS20230
gene id: 1109412:AWC36_RS20230
uniprot id: A0A0G4JTX7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

1109412:AWC36 RS04990
gene id: 1109412:AWC36_RS04990
uniprot id: A0A250BL16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS12960
gene id: 1109412:AWC36_RS12960
uniprot id: A0A0G4JPL4
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1109412:AWC36 RS19335
gene id: 1109412:AWC36_RS19335
uniprot id: A0A0G4JTH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
messages: Cell membrane

1109412:AWC36 RS08660
gene id: 1109412:AWC36_RS08660
uniprot id: A0A0G4K1K8
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1109412:AWC36 RS09765
gene id: 1109412:AWC36_RS09765
uniprot id: A0A0G4K2H2
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS19225
gene id: 1109412:AWC36_RS19225
uniprot id: A0A0G4JU19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS03275
gene id: 1109412:AWC36_RS03275
uniprot id: A0A0G4JXW3
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1109412:AWC36 RS09785
gene id: 1109412:AWC36_RS09785
uniprot id: A0A0G4K1P4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS03490
gene id: 1109412:AWC36_RS03490
uniprot id: A0A0G4JY15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin).
messages: Membrane

1109412:AWC36 RS12195
gene id: 1109412:AWC36_RS12195
uniprot id: A0A0G4JP59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1109412:AWC36 RS12370
gene id: 1109412:AWC36_RS12370
uniprot id: A0A0G4JP83
names: Similarity
messages: Belongs to the PhoH family.

1109412:AWC36 RS12530
gene id: 1109412:AWC36_RS12530
uniprot id: A0A0G4JPY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatA/E family. TatE subfamily.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA.

1109412:AWC36 RS04615
gene id: 1109412:AWC36_RS04615
uniprot id: A0A0G4JYV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1109412:AWC36 RS11915
gene id: 1109412:AWC36_RS11915
uniprot id: A0A0G4JP08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1109412:AWC36 RS21395
gene id: 1109412:AWC36_RS21395
uniprot id: A0A0G4JUQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1109412:AWC36 RS23210
gene id: 1109412:AWC36_RS23210
uniprot id: A0A0G4JW70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1109412:AWC36 RS10160
gene id: 1109412:AWC36_RS10160
uniprot id: A0A0G4K2P9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

1109412:AWC36 RS18900
gene id: 1109412:AWC36_RS18900
uniprot id: A0A0G4JT69
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1109412:AWC36 RS11675
gene id: 1109412:AWC36_RS11675
uniprot id: A0A0G4K3P4
names: Similarity
messages: Belongs to the CobH/CbiC family.

1109412:AWC36 RS10815
gene id: 1109412:AWC36_RS10815
uniprot id: A0A0G4K2I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1109412:AWC36 RS22430
gene id: 1109412:AWC36_RS22430
uniprot id: A0A0G4JVD8
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1109412:AWC36 RS19375
gene id: 1109412:AWC36_RS19375
uniprot id: A0A0G4JTH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS21505
gene id: 1109412:AWC36_RS21505
uniprot id: A0A0G4JUT0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1109412:AWC36 RS09175
gene id: 1109412:AWC36_RS09175
uniprot id: A0A0G4K205
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

1109412:AWC36 RS13055
gene id: 1109412:AWC36_RS13055
uniprot id: A0A0G4JQ45
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1109412:AWC36 RS18775
gene id: 1109412:AWC36_RS18775
uniprot id: A0A0G4JT62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1109412:AWC36 RS15260
gene id: 1109412:AWC36_RS15260
uniprot id: A0A0G4JR22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS22920
gene id: 1109412:AWC36_RS22920
uniprot id: A0A0G4JVB6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1109412:AWC36 RS06650
gene id: 1109412:AWC36_RS06650
uniprot id: A0A0G4JZS5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.
messages: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters.

1109412:AWC36 RS03385
gene id: 1109412:AWC36_RS03385
uniprot id: A0A0G4JXT3
names: Similarity
messages: Belongs to the HypD family.

1109412:AWC36 RS19395
gene id: 1109412:AWC36_RS19395
uniprot id: A0A0G4JTH6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1109412:AWC36 RS22760
gene id: 1109412:AWC36_RS22760
uniprot id: A0A0G4JVA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1109412:AWC36 RS19950
gene id: 1109412:AWC36_RS19950
uniprot id: A0A0G4JTS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1109412:AWC36 RS07775
gene id: 1109412:AWC36_RS07775
uniprot id: A0A0G4K0G1
names: Similarity
messages: Belongs to the UPF0482 family.

1109412:AWC36 RS10125
gene id: 1109412:AWC36_RS10125
uniprot id: A0A0G4K261
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1109412:AWC36 RS13595
gene id: 1109412:AWC36_RS13595
uniprot id: A0A0G4JPY6
names: Similarity
messages: Belongs to the UPF0253 family.

1109412:AWC36 RS22340
gene id: 1109412:AWC36_RS22340
uniprot id: A0A0G4JV32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1109412:AWC36 RS01720
gene id: 1109412:AWC36_RS01720
uniprot id: A0A0G4JWS1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1109412:AWC36 RS13665
gene id: 1109412:AWC36_RS13665
uniprot id: A0A0G4JQ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1109412:AWC36 RS14700
gene id: 1109412:AWC36_RS14700
uniprot id: A0A0G4JQP6
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1109412:AWC36 RS03140
gene id: 1109412:AWC36_RS03140
uniprot id: A0A0G4JYC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1109412:AWC36 RS05410
gene id: 1109412:AWC36_RS05410
uniprot id: A0A0G4JZT1
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1109412:AWC36 RS17005
gene id: 1109412:AWC36_RS17005
uniprot id: A0A0G4JS56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1109412:AWC36 RS08630
gene id: 1109412:AWC36_RS08630
uniprot id: A0A0G4K0T7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1109412:AWC36 RS03445
gene id: 1109412:AWC36_RS03445
uniprot id: A0A0G4JYI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Periplasm

1109412:AWC36 RS02820
gene id: 1109412:AWC36_RS02820
uniprot id: A0A0G4JXC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

1109412:AWC36 RS12005
gene id: 1109412:AWC36_RS12005
uniprot id: A0A0G4JP56
names: Similarity
messages: Belongs to the aldose epimerase family.

1109412:AWC36 RS22450
gene id: 1109412:AWC36_RS22450
uniprot id: A0A0G4JVT8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1109412:AWC36 RS19715
gene id: 1109412:AWC36_RS19715
uniprot id: A0A0G4JTS0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1109412:AWC36 RS09280
gene id: 1109412:AWC36_RS09280
uniprot id: A0A0G4K1J1
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS09845
gene id: 1109412:AWC36_RS09845
uniprot id: A0A0G4K218
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS02140
gene id: 1109412:AWC36_RS02140
uniprot id: A0A0G4JWX6
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1109412:AWC36 RS04425
gene id: 1109412:AWC36_RS04425
uniprot id: A0A0G4JYN7
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1109412:AWC36 RS14655
gene id: 1109412:AWC36_RS14655
uniprot id: A0A0G4JRB1
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1109412:AWC36 RS13705
gene id: 1109412:AWC36_RS13705
uniprot id: A0A0G4JQ10
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1109412:AWC36 RS09435
gene id: 1109412:AWC36_RS09435
uniprot id: A0A0G4K2A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

1109412:AWC36 RS18785
gene id: 1109412:AWC36_RS18785
uniprot id: A0A0G4JT31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1109412:AWC36 RS03810
gene id: 1109412:AWC36_RS03810
uniprot id: A0A0G4JY44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS05785
gene id: 1109412:AWC36_RS05785
uniprot id: A0A250BKX3
names: Similarity
messages: Belongs to the peptidase C40 family.

1109412:AWC36 RS18515
gene id: 1109412:AWC36_RS18515
uniprot id: A0A0G4JSV8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS07010
gene id: 1109412:AWC36_RS07010
uniprot id: A0A0G4K038
names: Similarity
messages: Belongs to the PspA/IM30 family.

1109412:AWC36 RS09860
gene id: 1109412:AWC36_RS09860
uniprot id: A0A0G4K1T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS18800
gene id: 1109412:AWC36_RS18800
uniprot id: A0A0G4JT66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1109412:AWC36 RS08415
gene id: 1109412:AWC36_RS08415
uniprot id: A0A0G4K0Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0266 family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS07795
gene id: 1109412:AWC36_RS07795
uniprot id: A0A0G4K177
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1109412:AWC36 RS21465
gene id: 1109412:AWC36_RS21465
uniprot id: A0A250BJL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1109412:AWC36 RS13660
gene id: 1109412:AWC36_RS13660
uniprot id: A0A0G4JPZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1109412:AWC36 RS13680
gene id: 1109412:AWC36_RS13680
uniprot id: A0A0G4JQH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1109412:AWC36 RS23615
gene id: 1109412:AWC36_RS23615
uniprot id: A0A0G4JVT9
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1109412:AWC36 RS05920
gene id: 1109412:AWC36_RS05920
uniprot id: A0A0G4JZ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

1109412:AWC36 RS22125
gene id: 1109412:AWC36_RS22125
uniprot id: A0A250BM13
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1109412:AWC36 RS13885
gene id: 1109412:AWC36_RS13885
uniprot id: A0A250BFP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

1109412:AWC36 RS13000
gene id: 1109412:AWC36_RS13000
uniprot id: A0A0G4JPP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1109412:AWC36 RS10585
gene id: 1109412:AWC36_RS10585
uniprot id: A0A0G4K274
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS23315
gene id: 1109412:AWC36_RS23315
uniprot id: A0A250BM30
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1109412:AWC36 RS04890
gene id: 1109412:AWC36_RS04890
uniprot id: A0A250BBI0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1109412:AWC36 RS11040
gene id: 1109412:AWC36_RS11040
uniprot id: A0A250BEL9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1109412:AWC36 RS17740
gene id: 1109412:AWC36_RS17740
uniprot id: A0A0G4JSE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1109412:AWC36 RS18050
gene id: 1109412:AWC36_RS18050
uniprot id: A0A250BI84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1109412:AWC36 RS06705
gene id: 1109412:AWC36_RS06705
uniprot id: A0A250BCY6
names: Similarity
messages: Belongs to the GST superfamily.

1109412:AWC36 RS15430
gene id: 1109412:AWC36_RS15430
uniprot id: A0A0G4JRN9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS23575
gene id: 1109412:AWC36_RS23575
uniprot id: A0A0G4JVS8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1109412:AWC36 RS15640
gene id: 1109412:AWC36_RS15640
uniprot id: A0A0G4JR93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1109412:AWC36 RS09595
gene id: 1109412:AWC36_RS09595
uniprot id: A0A0G4K1W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS21350
gene id: 1109412:AWC36_RS21350
uniprot id: A0A0G4JUM0
names: Similarity
messages: Belongs to the SlyX family.

1109412:AWC36 RS00175
gene id: 1109412:AWC36_RS00175
uniprot id: A0A0G4JWK9
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1109412:AWC36 RS14425
gene id: 1109412:AWC36_RS14425
uniprot id: A0A0G4JQJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

1109412:AWC36 RS04605
gene id: 1109412:AWC36_RS04605
uniprot id: A0A0G4JYR0
names: Similarity
messages: Belongs to the MoaD family.

1109412:AWC36 RS08985
gene id: 1109412:AWC36_RS08985
uniprot id: A0A0G4K1W3
names: Similarity
messages: Belongs to the pyruvate kinase family.

1109412:AWC36 RS21485
gene id: 1109412:AWC36_RS21485
uniprot id: A0A0G4JVE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1109412:AWC36 RS21470
gene id: 1109412:AWC36_RS21470
uniprot id: A0A0G4JUS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1109412:AWC36 RS21300
gene id: 1109412:AWC36_RS21300
uniprot id: A0A0G4JVB0
names: Similarity
messages: Belongs to the acetyltransferase YopJ family.

1109412:AWC36 RS12635
gene id: 1109412:AWC36_RS12635
uniprot id: A0A0G4JPD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaA family. HdA subfamily.
messages: Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA.
messages: The active form seems to be an ADP-bound monomer. Forms the RIDA complex (regulatory inactivation of DnaA) of ATP-DnaA, ADP-Hda and the DNA-loaded beta sliding clamp (dnaN).

1109412:AWC36 RS10465
gene id: 1109412:AWC36_RS10465
uniprot id: A0A0G4K2V3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS04315
gene id: 1109412:AWC36_RS04315
uniprot id: A0A0G4JYD5
names: Similarity
messages: Belongs to the MipA/OmpV family.

1109412:AWC36 RS09665
gene id: 1109412:AWC36_RS09665
uniprot id: A0A0G4K1M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1109412:AWC36 RS17565
gene id: 1109412:AWC36_RS17565
uniprot id: A0A0G4JSZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1109412:AWC36 RS07140
gene id: 1109412:AWC36_RS07140
uniprot id: A0A0G4K022
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1109412:AWC36 RS12950
gene id: 1109412:AWC36_RS12950
uniprot id: A0A0G4JPN6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1109412:AWC36 RS08330
gene id: 1109412:AWC36_RS08330
uniprot id: A0A0G4K0R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1109412:AWC36 RS18180
gene id: 1109412:AWC36_RS18180
uniprot id: A0A0G4JSP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS21330
gene id: 1109412:AWC36_RS21330
uniprot id: A0A250BJV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
messages: Cell inner membrane
messages: Interacts with KefB.
messages: Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.

1109412:AWC36 RS12110
gene id: 1109412:AWC36_RS12110
uniprot id: A0A0G4JPR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1109412:AWC36 RS22465
gene id: 1109412:AWC36_RS22465
uniprot id: A0A0G4JV81
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1109412:AWC36 RS07660
gene id: 1109412:AWC36_RS07660
uniprot id: A0A0G4K091
names: Similarity
messages: Belongs to the UPF0162 family.

1109412:AWC36 RS08195
gene id: 1109412:AWC36_RS08195
uniprot id: A0A0G4K0P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1109412:AWC36 RS07020
gene id: 1109412:AWC36_RS07020
uniprot id: A0A0G4JZW4
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS05870
gene id: 1109412:AWC36_RS05870
uniprot id: A0A0G4JZB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1109412:AWC36 RS20180
gene id: 1109412:AWC36_RS20180
uniprot id: A0A0G4JTW6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1109412:AWC36 RS13940
gene id: 1109412:AWC36_RS13940
uniprot id: A0A0G4JQC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Monomer.

1109412:AWC36 RS00300
gene id: 1109412:AWC36_RS00300
uniprot id: A0A0G4JW27
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Hexamer of two alpha, two beta, and two delta chains.

1109412:AWC36 RS13755
gene id: 1109412:AWC36_RS13755
uniprot id: A0A0G4JQ47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

1109412:AWC36 RS02730
gene id: 1109412:AWC36_RS02730
uniprot id: A0A0G4JXD9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1109412:AWC36 RS17220
gene id: 1109412:AWC36_RS17220
uniprot id: A0A0G4JSW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1109412:AWC36 RS23205
gene id: 1109412:AWC36_RS23205
uniprot id: A0A250BKB9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1109412:AWC36 RS21685
gene id: 1109412:AWC36_RS21685
uniprot id: A0A0G4JUV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldolase class II family. RhaD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
messages: Cytoplasm
messages: Homotetramer.

1109412:AWC36 RS18295
gene id: 1109412:AWC36_RS18295
uniprot id: A0A0G4JSS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS16160
gene id: 1109412:AWC36_RS16160
uniprot id: A0A0G4JRL3
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS08555
gene id: 1109412:AWC36_RS08555
uniprot id: A0A0G4K122
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1109412:AWC36 RS13065
gene id: 1109412:AWC36_RS13065
uniprot id: A0A250BF98
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1109412:AWC36 RS15505
gene id: 1109412:AWC36_RS15505
uniprot id: A0A0G4JRA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1109412:AWC36 RS12740
gene id: 1109412:AWC36_RS12740
uniprot id: A0A0G4JPI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1109412:AWC36 RS13710
gene id: 1109412:AWC36_RS13710
uniprot id: A0A0G4JQ37
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1109412:AWC36 RS12135
gene id: 1109412:AWC36_RS12135
uniprot id: A0A0G4JP61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS17765
gene id: 1109412:AWC36_RS17765
uniprot id: A0A0G4JSF5
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activity of this regulatory enzyme is affected by several metabolites. Allosterically and non-competitively inhibited by fructose 1,6-bisphosphate (FBP) and unphosphorylated phosphocarrier protein EIIA-Glc (III-Glc), an integral component of the bacterial phosphotransferase (PTS) system.
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium). Heterodimer with EIIA-Glc. Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1109412:AWC36 RS06465
gene id: 1109412:AWC36_RS06465
uniprot id: A0A0G4JZL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS16620
gene id: 1109412:AWC36_RS16620
uniprot id: A0A0G4JSK4
names: Similarity
messages: Belongs to the UPF0306 family.

1109412:AWC36 RS21540
gene id: 1109412:AWC36_RS21540
uniprot id: A0A0G4JVF4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1109412:AWC36 RS13735
gene id: 1109412:AWC36_RS13735
uniprot id: A0A0G4JQ40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

1109412:AWC36 RS17055
gene id: 1109412:AWC36_RS17055
uniprot id: A0A250BHF3
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

1109412:AWC36 RS09380
gene id: 1109412:AWC36_RS09380
uniprot id: A0A0G4K1I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1109412:AWC36 RS08095
gene id: 1109412:AWC36_RS08095
uniprot id: A0A0G4K0M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS17400
gene id: 1109412:AWC36_RS17400
uniprot id: A0A250BHX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS07715
gene id: 1109412:AWC36_RS07715
uniprot id: A0A0G4K0E7
names: Similarity
messages: Belongs to the YciI family.

1109412:AWC36 RS11655
gene id: 1109412:AWC36_RS11655
uniprot id: A0A0G4K2Y7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1109412:AWC36 RS22425
gene id: 1109412:AWC36_RS22425
uniprot id: A0A0G4JVT6
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1109412:AWC36 RS17095
gene id: 1109412:AWC36_RS17095
uniprot id: A0A0G4JS43
names: Similarity
messages: Belongs to the BolA/IbaG family.

1109412:AWC36 RS12025
gene id: 1109412:AWC36_RS12025
uniprot id: A0A0G4JP33
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1109412:AWC36 RS14950
gene id: 1109412:AWC36_RS14950
uniprot id: A0A0G4JQV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1109412:AWC36 RS02670
gene id: 1109412:AWC36_RS02670
uniprot id: A0A250BLU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1109412:AWC36 RS17900
gene id: 1109412:AWC36_RS17900
uniprot id: A0A0G4JSK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1109412:AWC36 RS01450
gene id: 1109412:AWC36_RS01450
uniprot id: A0A0G4JX70
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1109412:AWC36 RS10790
gene id: 1109412:AWC36_RS10790
uniprot id: A0A0G4K2B9
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS09025
gene id: 1109412:AWC36_RS09025
uniprot id: A0A0G4K1G4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1109412:AWC36 RS16900
gene id: 1109412:AWC36_RS16900
uniprot id: A0A0G4JS07
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1109412:AWC36 RS21365
gene id: 1109412:AWC36_RS21365
uniprot id: A0A0G4JUT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.

1109412:AWC36 RS13910
gene id: 1109412:AWC36_RS13910
uniprot id: A0A0G4JQ69
names: Similarity
messages: Belongs to the PrpF family.

1109412:AWC36 RS12985
gene id: 1109412:AWC36_RS12985
uniprot id: A0A0G4JPL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS15740
gene id: 1109412:AWC36_RS15740
uniprot id: A0A0G4JRV9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1109412:AWC36 RS10785
gene id: 1109412:AWC36_RS10785
uniprot id: A0A0G4K304
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1109412:AWC36 RS23260
gene id: 1109412:AWC36_RS23260
uniprot id: A0A0G4JW79
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS17420
gene id: 1109412:AWC36_RS17420
uniprot id: A0A0G4JSA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS00880
gene id: 1109412:AWC36_RS00880
uniprot id: A0A0G4JWA9
names: Similarity
messages: Belongs to the thioredoxin family.

1109412:AWC36 RS20875
gene id: 1109412:AWC36_RS20875
uniprot id: A0A0G4JUF4
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1109412:AWC36 RS05775
gene id: 1109412:AWC36_RS05775
uniprot id: A0A0G4JZG1
names: Function
names: Similarity
messages: Belongs to the glutathione peroxidase family. BtuE subfamily.
messages: Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent.

1109412:AWC36 RS21385
gene id: 1109412:AWC36_RS21385
uniprot id: A0A0G4JVC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1109412:AWC36 RS13150
gene id: 1109412:AWC36_RS13150
uniprot id: A0A0G4JQ59
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1109412:AWC36 RS15105
gene id: 1109412:AWC36_RS15105
uniprot id: A0A0G4JQY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

1109412:AWC36 RS12155
gene id: 1109412:AWC36_RS12155
uniprot id: A0A0G4JP58
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1109412:AWC36 RS08495
gene id: 1109412:AWC36_RS08495
uniprot id: A0A0G4K1I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS13195
gene id: 1109412:AWC36_RS13195
uniprot id: A0A250BFQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1109412:AWC36 RS10220
gene id: 1109412:AWC36_RS10220
uniprot id: A0A250BDW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1109412:AWC36 RS00535
gene id: 1109412:AWC36_RS00535
uniprot id: A0A0G4JW61
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS23645
gene id: 1109412:AWC36_RS23645
uniprot id: A0A0G4JWI1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1109412:AWC36 RS17915
gene id: 1109412:AWC36_RS17915
uniprot id: A0A0G4JSM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PanZ/PanM family.
messages: Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion.
messages: Interacts with PanD in the presence of CoA.

1109412:AWC36 RS08200
gene id: 1109412:AWC36_RS08200
uniprot id: A0A0G4K0U4
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1109412:AWC36 RS16465
gene id: 1109412:AWC36_RS16465
uniprot id: A0A0G4JRS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS20845
gene id: 1109412:AWC36_RS20845
uniprot id: A0A0G4JUC7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1109412:AWC36 RS22835
gene id: 1109412:AWC36_RS22835
uniprot id: A0A0G4JVC0
names: Similarity
messages: Belongs to the threonine synthase family.

1109412:AWC36 RS09430
gene id: 1109412:AWC36_RS09430
uniprot id: A0A0G4K1J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1109412:AWC36 RS13645
gene id: 1109412:AWC36_RS13645
uniprot id: A0A0G4JPZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1109412:AWC36 RS05365
gene id: 1109412:AWC36_RS05365
uniprot id: A0A250BBU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

1109412:AWC36 RS01565
gene id: 1109412:AWC36_RS01565
uniprot id: A0A0G4JWK8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1109412:AWC36 RS22165
gene id: 1109412:AWC36_RS22165
uniprot id: A0A0G4JV35
names: Subcellular Location Annotation
messages: Cytoplasm

1109412:AWC36 RS07515
gene id: 1109412:AWC36_RS07515
uniprot id: A0A0G4K071
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1109412:AWC36 RS15715
gene id: 1109412:AWC36_RS15715
uniprot id: A0A0G4JRV2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1109412:AWC36 RS03130
gene id: 1109412:AWC36_RS03130
uniprot id: A0A0G4JXK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

1109412:AWC36 RS21310
gene id: 1109412:AWC36_RS21310
uniprot id: A0A0G4JUP2
names: Similarity
messages: Belongs to the UPF0270 family.

1109412:AWC36 RS08615
gene id: 1109412:AWC36_RS08615
uniprot id: A0A0G4K1K0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1109412:AWC36 RS05430
gene id: 1109412:AWC36_RS05430
uniprot id: A0A250BBS1
names: Similarity
messages: Belongs to the acylphosphatase family.

1109412:AWC36 RS21285
gene id: 1109412:AWC36_RS21285
uniprot id: A0A0G4JUN7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1109412:AWC36 RS02555
gene id: 1109412:AWC36_RS02555
uniprot id: A0A250BKS3
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1109412:AWC36 RS12495
gene id: 1109412:AWC36_RS12495
uniprot id: A0A0G4JPA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1109412:AWC36 RS09635
gene id: 1109412:AWC36_RS09635
uniprot id: A0A0G4K1N9
names: Similarity
names: Subunit
messages: Belongs to the glutaredoxin family.
messages: Monomer.

1109412:AWC36 RS09470
gene id: 1109412:AWC36_RS09470
uniprot id: A0A0G4K1U2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS21515
gene id: 1109412:AWC36_RS21515
uniprot id: A0A0G4JUW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1109412:AWC36 RS03190
gene id: 1109412:AWC36_RS03190
uniprot id: A0A0G4JYD6
names: Subcellular Location Annotation
messages: Membrane

1109412:AWC36 RS05375
gene id: 1109412:AWC36_RS05375
uniprot id: A0A0G4JZ97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MatP family.
messages: Cytoplasm
messages: Homodimer.
messages: Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.

1109412:AWC36 RS23650
gene id: 1109412:AWC36_RS23650
uniprot id: A0A0G4JVX7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1109412:AWC36 RS20305
gene id: 1109412:AWC36_RS20305
uniprot id: A0A250BJD0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1109412:AWC36 RS20660
gene id: 1109412:AWC36_RS20660
uniprot id: A0A0G4JU72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1109412:AWC36 RS07640
gene id: 1109412:AWC36_RS07640
uniprot id: A0A0G4K144
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1109412:AWC36 RS03320
gene id: 1109412:AWC36_RS03320
uniprot id: A0A0G4JXU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

1109412:AWC36 RS08865
gene id: 1109412:AWC36_RS08865
uniprot id: A0A0G4K187
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1109412:AWC36 RS23245
gene id: 1109412:AWC36_RS23245
uniprot id: A0A0G4JVJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1109412:AWC36 RS09420
gene id: 1109412:AWC36_RS09420
uniprot id: A0A0G4K1Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1109412:AWC36 RS15730
gene id: 1109412:AWC36_RS15730
uniprot id: A0A0G4JRA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1109412:AWC36 RS17150
gene id: 1109412:AWC36_RS17150
uniprot id: A0A0G4JS58
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1109412:AWC36 RS05680
gene id: 1109412:AWC36_RS05680
uniprot id: A0A0G4JZ46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LpoB family.
messages: Cell outer membrane
messages: Interacts with PBP1b.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).

1109412:AWC36 RS08165
gene id: 1109412:AWC36_RS08165
uniprot id: A0A0G4K0T9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RssB family.
messages: Binds to RpoS.
messages: Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.
messages: Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.

1109412:AWC36 RS13015
gene id: 1109412:AWC36_RS13015
uniprot id: A0A0G4JPL3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1109412:AWC36 RS03355
gene id: 1109412:AWC36_RS03355
uniprot id: A0A0G4JYH1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

1109412:AWC36 RS00915
gene id: 1109412:AWC36_RS00915
uniprot id: A0A0G4JWD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1109412:AWC36 RS15725
gene id: 1109412:AWC36_RS15725
uniprot id: A0A250BH12
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1109412:AWC36 RS07880
gene id: 1109412:AWC36_RS07880
uniprot id: A0A0G4K0P2
names: Similarity
messages: Belongs to the ribulokinase family.

1109412:AWC36 RS10175
gene id: 1109412:AWC36_RS10175
uniprot id: A0A0G4K1X1
names: Similarity
messages: Belongs to the DsrB family.

1109412:AWC36 RS17065
gene id: 1109412:AWC36_RS17065
uniprot id: A0A250BHA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1109412:AWC36 RS07275
gene id: 1109412:AWC36_RS07275
uniprot id: A0A0G4K0D8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1109412:AWC36 RS21190
gene id: 1109412:AWC36_RS21190
uniprot id: A0A250BJG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1109412:AWC36 RS02075
gene id: 1109412:AWC36_RS02075
uniprot id: A0A0G4JWZ3
names: Similarity
messages: Belongs to the P(II) protein family.

1109412:AWC36 RS21210
gene id: 1109412:AWC36_RS21210
uniprot id: A0A0G4JUM1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1109412:AWC36 RS15405
gene id: 1109412:AWC36_RS15405
uniprot id: A0A0G4JRN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1109412:AWC36 RS21245
gene id: 1109412:AWC36_RS21245
uniprot id: A0A0G4JUJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1109412:AWC36 RS19130
gene id: 1109412:AWC36_RS19130
uniprot id: A0A0G4JU03
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1109412:AWC36 RS12915
gene id: 1109412:AWC36_RS12915
uniprot id: A0A0G4JQ38
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1109412:AWC36 RS13395
gene id: 1109412:AWC36_RS13395
uniprot id: A0A250BFW4
names: Similarity
messages: Belongs to the asparaginase 1 family.

1109412:AWC36 RS07895
gene id: 1109412:AWC36_RS07895
uniprot id: A0A0G4K196
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1109412:AWC36 RS16030
gene id: 1109412:AWC36_RS16030
uniprot id: A0A0G4JS32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

1109412:AWC36 RS01580
gene id: 1109412:AWC36_RS01580
uniprot id: A0A0G4JX77
names: Function
names: Subunit
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.
messages: The DNA polymerase holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential subassemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core (subunits alpha,epsilon and theta) contains the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. This complex contains delta, delta', psi and chi, and copies of either or both of two different DnaX proteins, gamma and tau.

1109412:AWC36 RS12825
gene id: 1109412:AWC36_RS12825
uniprot id: A0A0G4JPI5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1109412:AWC36 RS18745
gene id: 1109412:AWC36_RS18745
uniprot id: A0A0G4JT16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1109412:AWC36 RS13650
gene id: 1109412:AWC36_RS13650
uniprot id: A0A0G4JQ13
names: Similarity
messages: Belongs to the skp family.

1109412:AWC36 RS12035
gene id: 1109412:AWC36_RS12035
uniprot id: A0A0G4JP41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1109412:AWC36 RS20285
gene id: 1109412:AWC36_RS20285
uniprot id: A0A0G4JU05
names: Function
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.
messages: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.

1109412:AWC36 RS05955
gene id: 1109412:AWC36_RS05955
uniprot id: A0A0G4JZK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: Membrane

1109412:AWC36 RS06755
gene id: 1109412:AWC36_RS06755
uniprot id: A0A0G4K006
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.