1094466:KQS RS02960
gene id: 1094466:KQS_RS02960
uniprot id: H8XSK3
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

1094466:KQS RS07160
gene id: 1094466:KQS_RS07160
uniprot id: H8XQV4
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1094466:KQS RS12605
gene id: 1094466:KQS_RS12605
uniprot id: H8XRK9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1094466:KQS RS10120
gene id: 1094466:KQS_RS10120
uniprot id: H8XVL1
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS13165
gene id: 1094466:KQS_RS13165
uniprot id: H8XRW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for cell division and gliding motility.

1094466:KQS RS01590
gene id: 1094466:KQS_RS01590
uniprot id: H8XP45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1094466:KQS RS02645
gene id: 1094466:KQS_RS02645
uniprot id: H8XSD7
names: Similarity
messages: Belongs to the GbsR family.

1094466:KQS RS12100
gene id: 1094466:KQS_RS12100
uniprot id: H8XRB2
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS06935
gene id: 1094466:KQS_RS06935
uniprot id: H8XQQ9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1094466:KQS RS09670
gene id: 1094466:KQS_RS09670
uniprot id: H8XUV7
names: Similarity
messages: Belongs to the malate synthase family.

1094466:KQS RS02175
gene id: 1094466:KQS_RS02175
uniprot id: H8XQD5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1094466:KQS RS12920
gene id: 1094466:KQS_RS12920
uniprot id: H8XRR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1094466:KQS RS09080
gene id: 1094466:KQS_RS09080
uniprot id: H8XUJ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS12500
gene id: 1094466:KQS_RS12500
uniprot id: H8XRI9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1094466:KQS RS02015
gene id: 1094466:KQS_RS02015
uniprot id: H8XQA3
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS00650
gene id: 1094466:KQS_RS00650
uniprot id: H8XNL4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1094466:KQS RS11790
gene id: 1094466:KQS_RS11790
uniprot id: H8XR51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1094466:KQS RS13150
gene id: 1094466:KQS_RS13150
uniprot id: H8XRW0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS08360
gene id: 1094466:KQS_RS08360
uniprot id: H8XTQ1
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS09290
gene id: 1094466:KQS_RS09290
uniprot id: H8XUN4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS10640
gene id: 1094466:KQS_RS10640
uniprot id: H8XVW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1094466:KQS RS09960
gene id: 1094466:KQS_RS09960
uniprot id: H8XVH8
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS06285
gene id: 1094466:KQS_RS06285
uniprot id: H8XPF2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1094466:KQS RS03925
gene id: 1094466:KQS_RS03925
uniprot id: H8XTH3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1094466:KQS RS06865
gene id: 1094466:KQS_RS06865
uniprot id: H8XQP5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1094466:KQS RS13005
gene id: 1094466:KQS_RS13005
uniprot id: H8XRT2
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1094466:KQS RS02030
gene id: 1094466:KQS_RS02030
uniprot id: H8XQA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1094466:KQS RS05235
gene id: 1094466:KQS_RS05235
uniprot id: H8XV56
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1094466:KQS RS05210
gene id: 1094466:KQS_RS05210
uniprot id: H8XV51
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS09590
gene id: 1094466:KQS_RS09590
uniprot id: H8XUU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1094466:KQS RS00240
gene id: 1094466:KQS_RS00240
uniprot id: H8XNE5
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1094466:KQS RS03820
gene id: 1094466:KQS_RS03820
uniprot id: H8XTF7
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS10070
gene id: 1094466:KQS_RS10070
uniprot id: H8XVK1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1094466:KQS RS01720
gene id: 1094466:KQS_RS01720
uniprot id: H8XQ44
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1094466:KQS RS05305
gene id: 1094466:KQS_RS05305
uniprot id: H8XV70
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1094466:KQS RS08615
gene id: 1094466:KQS_RS08615
uniprot id: H8XTV1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1094466:KQS RS08745
gene id: 1094466:KQS_RS08745
uniprot id: H8XTX5
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1094466:KQS RS03880
gene id: 1094466:KQS_RS03880
uniprot id: H8XTG4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1094466:KQS RS07440
gene id: 1094466:KQS_RS07440
uniprot id: H8XR10
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1094466:KQS RS03230
gene id: 1094466:KQS_RS03230
uniprot id: H8XSQ2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1094466:KQS RS13845
gene id: 1094466:KQS_RS13845
uniprot id: H8XS98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

1094466:KQS RS13380
gene id: 1094466:KQS_RS13380
uniprot id: H8XS06
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1094466:KQS RS02560
gene id: 1094466:KQS_RS02560
uniprot id: H8XSC0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1094466:KQS RS04365
gene id: 1094466:KQS_RS04365
uniprot id: H8XU75
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1094466:KQS RS03535
gene id: 1094466:KQS_RS03535
uniprot id: H8XTA1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1094466:KQS RS04100
gene id: 1094466:KQS_RS04100
uniprot id: H8XTK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1094466:KQS RS06245
gene id: 1094466:KQS_RS06245
uniprot id: H8XPE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1094466:KQS RS09305
gene id: 1094466:KQS_RS09305
uniprot id: H8XUN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1094466:KQS RS11345
gene id: 1094466:KQS_RS11345
uniprot id: H8XPZ1
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1094466:KQS RS03765
gene id: 1094466:KQS_RS03765
uniprot id: H8XTE6
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1094466:KQS RS08175
gene id: 1094466:KQS_RS08175
uniprot id: H8XT51
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1094466:KQS RS11265
gene id: 1094466:KQS_RS11265
uniprot id: H8XPX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1094466:KQS RS10970
gene id: 1094466:KQS_RS10970
uniprot id: H8XPS1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1094466:KQS RS09445
gene id: 1094466:KQS_RS09445
uniprot id: H8XUR4
names: Similarity
messages: Belongs to the YciI family.

1094466:KQS RS03770
gene id: 1094466:KQS_RS03770
uniprot id: H8XTE7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1094466:KQS RS08240
gene id: 1094466:KQS_RS08240
uniprot id: H8XTM7
names: Similarity
messages: Belongs to the YciI family.

1094466:KQS RS02745
gene id: 1094466:KQS_RS02745
uniprot id: H8XSF8
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1094466:KQS RS09115
gene id: 1094466:KQS_RS09115
uniprot id: H8XUJ9
names: Similarity
messages: Belongs to the LOG family.

1094466:KQS RS03505
gene id: 1094466:KQS_RS03505
uniprot id: H8XT95
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1094466:KQS RS03875
gene id: 1094466:KQS_RS03875
uniprot id: H8XTG3
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS01170
gene id: 1094466:KQS_RS01170
uniprot id: H8XNW5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1094466:KQS RS06410
gene id: 1094466:KQS_RS06410
uniprot id: H8XPH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1094466:KQS RS03815
gene id: 1094466:KQS_RS03815
uniprot id: H8XTF6
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1094466:KQS RS06005
gene id: 1094466:KQS_RS06005
uniprot id: H8XPA0
names: Similarity
messages: Belongs to the barstar family.

1094466:KQS RS07235
gene id: 1094466:KQS_RS07235
uniprot id: H8XQW9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1094466:KQS RS12910
gene id: 1094466:KQS_RS12910
uniprot id: H8XRR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1094466:KQS RS10870
gene id: 1094466:KQS_RS10870
uniprot id: H8XPQ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS10565
gene id: 1094466:KQS_RS10565
uniprot id: H8XVU7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1094466:KQS RS04960
gene id: 1094466:KQS_RS04960
uniprot id: H8XUZ6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1094466:KQS RS04455
gene id: 1094466:KQS_RS04455
uniprot id: H8XU92
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS09365
gene id: 1094466:KQS_RS09365
uniprot id: H8XUP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1094466:KQS RS01705
gene id: 1094466:KQS_RS01705
uniprot id: H8XQ41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1094466:KQS RS09680
gene id: 1094466:KQS_RS09680
uniprot id: H8XUV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1094466:KQS RS10990
gene id: 1094466:KQS_RS10990
uniprot id: H8XPS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1094466:KQS RS11690
gene id: 1094466:KQS_RS11690
uniprot id: H8XR31
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1094466:KQS RS12425
gene id: 1094466:KQS_RS12425
uniprot id: H8XRH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1094466:KQS RS02890
gene id: 1094466:KQS_RS02890
uniprot id: H8XSI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1094466:KQS RS02335
gene id: 1094466:KQS_RS02335
uniprot id: H8XQG7
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1094466:KQS RS09970
gene id: 1094466:KQS_RS09970
uniprot id: H8XVI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1094466:KQS RS02665
gene id: 1094466:KQS_RS02665
uniprot id: H8XSE2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS03705
gene id: 1094466:KQS_RS03705
uniprot id: H8XTD4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1094466:KQS RS04780
gene id: 1094466:KQS_RS04780
uniprot id: H8XUE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Membrane

1094466:KQS RS10705
gene id: 1094466:KQS_RS10705
uniprot id: H8XPL9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1094466:KQS RS05550
gene id: 1094466:KQS_RS05550
uniprot id: H8XVB6
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1094466:KQS RS12385
gene id: 1094466:KQS_RS12385
uniprot id: H8XRG6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1094466:KQS RS02420
gene id: 1094466:KQS_RS02420
uniprot id: H8XQI4
names: Similarity
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1094466:KQS RS02490
gene id: 1094466:KQS_RS02490
uniprot id: H8XSA6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

1094466:KQS RS08355
gene id: 1094466:KQS_RS08355
uniprot id: H8XTQ0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1094466:KQS RS13095
gene id: 1094466:KQS_RS13095
uniprot id: H8XRU9
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1094466:KQS RS07000
gene id: 1094466:KQS_RS07000
uniprot id: H8XQS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1094466:KQS RS03525
gene id: 1094466:KQS_RS03525
uniprot id: H8XT99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1094466:KQS RS11560
gene id: 1094466:KQS_RS11560
uniprot id: H8XR15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1094466:KQS RS03595
gene id: 1094466:KQS_RS03595
uniprot id: H8XTB3
names: Similarity
messages: Belongs to the IMPACT family.

1094466:KQS RS07170
gene id: 1094466:KQS_RS07170
uniprot id: H8XQV6
names: Similarity
messages: Belongs to the UPF0246 family.

1094466:KQS RS07065
gene id: 1094466:KQS_RS07065
uniprot id: H8XQT4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1094466:KQS RS06635
gene id: 1094466:KQS_RS06635
uniprot id: H8XQJ7
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1094466:KQS RS00030
gene id: 1094466:KQS_RS00030
uniprot id: H8XNA4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1094466:KQS RS09495
gene id: 1094466:KQS_RS09495
uniprot id: H8XUS4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1094466:KQS RS06630
gene id: 1094466:KQS_RS06630
uniprot id: H8XQJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1094466:KQS RS13630
gene id: 1094466:KQS_RS13630
uniprot id: H8XS56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1094466:KQS RS12320
gene id: 1094466:KQS_RS12320
uniprot id: H8XRF3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1094466:KQS RS10555
gene id: 1094466:KQS_RS10555
uniprot id: H8XVU5
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1094466:KQS RS10545
gene id: 1094466:KQS_RS10545
uniprot id: H8XVU3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1094466:KQS RS12715
gene id: 1094466:KQS_RS12715
uniprot id: H8XRN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1094466:KQS RS13785
gene id: 1094466:KQS_RS13785
uniprot id: H8XS87
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1094466:KQS RS11710
gene id: 1094466:KQS_RS11710
uniprot id: H8XR35
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1094466:KQS RS01585
gene id: 1094466:KQS_RS01585
uniprot id: H8XP44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1094466:KQS RS01490
gene id: 1094466:KQS_RS01490
uniprot id: H8XP26
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1094466:KQS RS08485
gene id: 1094466:KQS_RS08485
uniprot id: H8XTS5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1094466:KQS RS06795
gene id: 1094466:KQS_RS06795
uniprot id: H8XQN0
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1094466:KQS RS09405
gene id: 1094466:KQS_RS09405
uniprot id: H8XUQ6
names: Similarity
messages: Belongs to the YicC/YloC family.

1094466:KQS RS06820
gene id: 1094466:KQS_RS06820
uniprot id: H8XQN5
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS13530
gene id: 1094466:KQS_RS13530
uniprot id: H8XS36
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1094466:KQS RS05270
gene id: 1094466:KQS_RS05270
uniprot id: H8XV63
names: Similarity
messages: Belongs to the peptidase S33 family.

1094466:KQS RS03120
gene id: 1094466:KQS_RS03120
uniprot id: H8XSN0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1094466:KQS RS01900
gene id: 1094466:KQS_RS01900
uniprot id: H8XQ80
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1094466:KQS RS02410
gene id: 1094466:KQS_RS02410
uniprot id: H8XQI2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1094466:KQS RS01525
gene id: 1094466:KQS_RS01525
uniprot id: H8XP33
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS12665
gene id: 1094466:KQS_RS12665
uniprot id: H8XRM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1094466:KQS RS05280
gene id: 1094466:KQS_RS05280
uniprot id: H8XV65
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

1094466:KQS RS01545
gene id: 1094466:KQS_RS01545
uniprot id: H8XP37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1094466:KQS RS12615
gene id: 1094466:KQS_RS12615
uniprot id: H8XRL1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1094466:KQS RS00295
gene id: 1094466:KQS_RS00295
uniprot id: H8XNF6
names: Similarity
messages: Belongs to the peptidase M13 family.

1094466:KQS RS12575
gene id: 1094466:KQS_RS12575
uniprot id: H8XRK3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1094466:KQS RS05275
gene id: 1094466:KQS_RS05275
uniprot id: H8XV64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

1094466:KQS RS12010
gene id: 1094466:KQS_RS12010
uniprot id: H8XR94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

1094466:KQS RS08680
gene id: 1094466:KQS_RS08680
uniprot id: H8XTW3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1094466:KQS RS09595
gene id: 1094466:KQS_RS09595
uniprot id: H8XUU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1094466:KQS RS06915
gene id: 1094466:KQS_RS06915
uniprot id: H8XQQ5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1094466:KQS RS01630
gene id: 1094466:KQS_RS01630
uniprot id: H8XP53
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

1094466:KQS RS09650
gene id: 1094466:KQS_RS09650
uniprot id: H8XUV3
names: Similarity
messages: Belongs to the BshC family.

1094466:KQS RS02980
gene id: 1094466:KQS_RS02980
uniprot id: H8XSK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1094466:KQS RS09660
gene id: 1094466:KQS_RS09660
uniprot id: H8XUV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1094466:KQS RS06065
gene id: 1094466:KQS_RS06065
uniprot id: H8XPB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1094466:KQS RS02360
gene id: 1094466:KQS_RS02360
uniprot id: H8XQH2
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1094466:KQS RS12805
gene id: 1094466:KQS_RS12805
uniprot id: H8XRP7
names: Similarity
messages: Belongs to the UPF0102 family.

1094466:KQS RS04380
gene id: 1094466:KQS_RS04380
uniprot id: H8XU78
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS04945
gene id: 1094466:KQS_RS04945
uniprot id: H8XUI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1094466:KQS RS00190
gene id: 1094466:KQS_RS00190
uniprot id: H8XND5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1094466:KQS RS07255
gene id: 1094466:KQS_RS07255
uniprot id: H8XQX3
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1094466:KQS RS10045
gene id: 1094466:KQS_RS10045
uniprot id: H8XVJ6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1094466:KQS RS07015
gene id: 1094466:KQS_RS07015
uniprot id: H8XQS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1094466:KQS RS12105
gene id: 1094466:KQS_RS12105
uniprot id: H8XRB3
names: Similarity
messages: Belongs to the ribF family.

1094466:KQS RS08500
gene id: 1094466:KQS_RS08500
uniprot id: H8XTS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1094466:KQS RS00150
gene id: 1094466:KQS_RS00150
uniprot id: H8XNC8
names: Similarity
messages: Belongs to the peptidase S8 family.

1094466:KQS RS09505
gene id: 1094466:KQS_RS09505
uniprot id: H8XUS6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1094466:KQS RS06080
gene id: 1094466:KQS_RS06080
uniprot id: H8XPB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1094466:KQS RS10110
gene id: 1094466:KQS_RS10110
uniprot id: H8XVK9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1094466:KQS RS07390
gene id: 1094466:KQS_RS07390
uniprot id: H8XR00
names: Similarity
messages: Belongs to the Lgt family.

1094466:KQS RS10660
gene id: 1094466:KQS_RS10660
uniprot id: H8XVW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1094466:KQS RS05410
gene id: 1094466:KQS_RS05410
uniprot id: H8XV91
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1094466:KQS RS04440
gene id: 1094466:KQS_RS04440
uniprot id: H8XU89
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1094466:KQS RS10760
gene id: 1094466:KQS_RS10760
uniprot id: H8XPN0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1094466:KQS RS00980
gene id: 1094466:KQS_RS00980
uniprot id: H8XNS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1094466:KQS RS08755
gene id: 1094466:KQS_RS08755
uniprot id: H8XTX7
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS13290
gene id: 1094466:KQS_RS13290
uniprot id: H8XRY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1094466:KQS RS08560
gene id: 1094466:KQS_RS08560
uniprot id: H8XTU0
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

1094466:KQS RS00680
gene id: 1094466:KQS_RS00680
uniprot id: H8XNM0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1094466:KQS RS05765
gene id: 1094466:KQS_RS05765
uniprot id: H8XVF9
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1094466:KQS RS05710
gene id: 1094466:KQS_RS05710
uniprot id: H8XVE7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1094466:KQS RS09240
gene id: 1094466:KQS_RS09240
uniprot id: H8XUM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1094466:KQS RS07130
gene id: 1094466:KQS_RS07130
uniprot id: H8XQU7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1094466:KQS RS01510
gene id: 1094466:KQS_RS01510
uniprot id: H8XP30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1094466:KQS RS00480
gene id: 1094466:KQS_RS00480
uniprot id: H8XNI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1094466:KQS RS06155
gene id: 1094466:KQS_RS06155
uniprot id: H8XPC9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1094466:KQS RS10505
gene id: 1094466:KQS_RS10505
uniprot id: H8XVT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1094466:KQS RS04430
gene id: 1094466:KQS_RS04430
uniprot id: H8XU87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

1094466:KQS RS09810
gene id: 1094466:KQS_RS09810
uniprot id: H8XUY3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1094466:KQS RS01945
gene id: 1094466:KQS_RS01945
uniprot id: H8XQ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Cytoplasm

1094466:KQS RS00370
gene id: 1094466:KQS_RS00370
uniprot id: H8XNH0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1094466:KQS RS00990
gene id: 1094466:KQS_RS00990
uniprot id: H8XNS8
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS12405
gene id: 1094466:KQS_RS12405
uniprot id: H8XRH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1094466:KQS RS13595
gene id: 1094466:KQS_RS13595
uniprot id: H8XS49
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1094466:KQS RS12035
gene id: 1094466:KQS_RS12035
uniprot id: H8XR99
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1094466:KQS RS12835
gene id: 1094466:KQS_RS12835
uniprot id: H8XRQ3
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS01990
gene id: 1094466:KQS_RS01990
uniprot id: H8XQ98
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1094466:KQS RS00250
gene id: 1094466:KQS_RS00250
uniprot id: H8XNE7
names: Similarity
messages: Belongs to the peptidase S24 family.

1094466:KQS RS01270
gene id: 1094466:KQS_RS01270
uniprot id: H8XNY5
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS00670
gene id: 1094466:KQS_RS00670
uniprot id: H8XNL8
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1094466:KQS RS00085
gene id: 1094466:KQS_RS00085
uniprot id: H8XNB5
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS12045
gene id: 1094466:KQS_RS12045
uniprot id: H8XRA1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS02090
gene id: 1094466:KQS_RS02090
uniprot id: H8XQB8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1094466:KQS RS07895
gene id: 1094466:KQS_RS07895
uniprot id: H8XSZ7
names: Subunit
messages: Monomer.

1094466:KQS RS08555
gene id: 1094466:KQS_RS08555
uniprot id: H8XTT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1094466:KQS RS04715
gene id: 1094466:KQS_RS04715
uniprot id: H8XUD6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1094466:KQS RS09925
gene id: 1094466:KQS_RS09925
uniprot id: H8XVH1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1094466:KQS RS04150
gene id: 1094466:KQS_RS04150
uniprot id: H8XU32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1094466:KQS RS12650
gene id: 1094466:KQS_RS12650
uniprot id: H8XRL8
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS12810
gene id: 1094466:KQS_RS12810
uniprot id: H8XRP8
names: Similarity
messages: Belongs to the peptidase S66 family.

1094466:KQS RS13795
gene id: 1094466:KQS_RS13795
uniprot id: H8XS89
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1094466:KQS RS03990
gene id: 1094466:KQS_RS03990
uniprot id: H8XTI6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1094466:KQS RS01180
gene id: 1094466:KQS_RS01180
uniprot id: H8XNW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1094466:KQS RS12935
gene id: 1094466:KQS_RS12935
uniprot id: H8XRS2
names: Similarity
messages: Belongs to the DtxR/MntR family.

1094466:KQS RS08540
gene id: 1094466:KQS_RS08540
uniprot id: H8XTT6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1094466:KQS RS06945
gene id: 1094466:KQS_RS06945
uniprot id: H8XQR1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1094466:KQS RS12400
gene id: 1094466:KQS_RS12400
uniprot id: H8XRG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1094466:KQS RS06955
gene id: 1094466:KQS_RS06955
uniprot id: H8XQR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1094466:KQS RS09455
gene id: 1094466:KQS_RS09455
uniprot id: H8XUR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1094466:KQS RS01530
gene id: 1094466:KQS_RS01530
uniprot id: H8XP34
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1094466:KQS RS03685
gene id: 1094466:KQS_RS03685
uniprot id: H8XTD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1094466:KQS RS01075
gene id: 1094466:KQS_RS01075
uniprot id: H8XNU6
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1094466:KQS RS07340
gene id: 1094466:KQS_RS07340
uniprot id: H8XQZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

1094466:KQS RS04710
gene id: 1094466:KQS_RS04710
uniprot id: H8XUD5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS10625
gene id: 1094466:KQS_RS10625
uniprot id: H8XVV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1094466:KQS RS12170
gene id: 1094466:KQS_RS12170
uniprot id: H8XRC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1094466:KQS RS01700
gene id: 1094466:KQS_RS01700
uniprot id: H8XQ40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1094466:KQS RS10035
gene id: 1094466:KQS_RS10035
uniprot id: H8XVJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1094466:KQS RS11905
gene id: 1094466:KQS_RS11905
uniprot id: H8XR76
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1094466:KQS RS13265
gene id: 1094466:KQS_RS13265
uniprot id: H8XRY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1094466:KQS RS02810
gene id: 1094466:KQS_RS02810
uniprot id: H8XSH2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1094466:KQS RS02950
gene id: 1094466:KQS_RS02950
uniprot id: H8XSK1
names: Similarity
messages: Belongs to the arginase family.

1094466:KQS RS00630
gene id: 1094466:KQS_RS00630
uniprot id: H8XNL0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1094466:KQS RS07150
gene id: 1094466:KQS_RS07150
uniprot id: H8XQV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1094466:KQS RS11720
gene id: 1094466:KQS_RS11720
uniprot id: H8XR37
names: Similarity
messages: Belongs to the NAD synthetase family.

1094466:KQS RS03105
gene id: 1094466:KQS_RS03105
uniprot id: H8XSM7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1094466:KQS RS12000
gene id: 1094466:KQS_RS12000
uniprot id: H8XR92
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1094466:KQS RS02235
gene id: 1094466:KQS_RS02235
uniprot id: H8XQE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS07115
gene id: 1094466:KQS_RS07115
uniprot id: H8XQU4
names: Similarity
messages: Belongs to the RutC family.

1094466:KQS RS01450
gene id: 1094466:KQS_RS01450
uniprot id: H8XP18
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1094466:KQS RS02915
gene id: 1094466:KQS_RS02915
uniprot id: H8XSJ4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1094466:KQS RS00160
gene id: 1094466:KQS_RS00160
uniprot id: H8XND0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1094466:KQS RS10575
gene id: 1094466:KQS_RS10575
uniprot id: H8XVU9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1094466:KQS RS05485
gene id: 1094466:KQS_RS05485
uniprot id: H8XVA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1094466:KQS RS03165
gene id: 1094466:KQS_RS03165
uniprot id: H8XSN9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1094466:KQS RS10100
gene id: 1094466:KQS_RS10100
uniprot id: H8XVK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS04125
gene id: 1094466:KQS_RS04125
uniprot id: H8XTL3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1094466:KQS RS09130
gene id: 1094466:KQS_RS09130
uniprot id: H8XUK2
names: Similarity
messages: Belongs to the asparagine synthetase family.

1094466:KQS RS00640
gene id: 1094466:KQS_RS00640
uniprot id: H8XNL2
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS02930
gene id: 1094466:KQS_RS02930
uniprot id: H8XSJ7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1094466:KQS RS11970
gene id: 1094466:KQS_RS11970
uniprot id: H8XR86
names: Similarity
messages: Belongs to the peptidase S49 family.

1094466:KQS RS04020
gene id: 1094466:KQS_RS04020
uniprot id: H8XTJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1094466:KQS RS13435
gene id: 1094466:KQS_RS13435
uniprot id: H8XS17
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1094466:KQS RS01810
gene id: 1094466:KQS_RS01810
uniprot id: H8XQ62
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS11440
gene id: 1094466:KQS_RS11440
uniprot id: H8XQ08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1094466:KQS RS03950
gene id: 1094466:KQS_RS03950
uniprot id: H8XTH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1094466:KQS RS03035
gene id: 1094466:KQS_RS03035
uniprot id: H8XSL8
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS02830
gene id: 1094466:KQS_RS02830
uniprot id: H8XSH6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1094466:KQS RS02825
gene id: 1094466:KQS_RS02825
uniprot id: H8XSH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1094466:KQS RS00120
gene id: 1094466:KQS_RS00120
uniprot id: H8XNC2
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1094466:KQS RS12280
gene id: 1094466:KQS_RS12280
uniprot id: H8XRE5
names: Similarity
messages: Belongs to the peptidase S9C family.

1094466:KQS RS05335
gene id: 1094466:KQS_RS05335
uniprot id: H8XV76
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1094466:KQS RS05250
gene id: 1094466:KQS_RS05250
uniprot id: H8XV59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

1094466:KQS RS13235
gene id: 1094466:KQS_RS13235
uniprot id: H8XRX7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

1094466:KQS RS03930
gene id: 1094466:KQS_RS03930
uniprot id: H8XTH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1094466:KQS RS09170
gene id: 1094466:KQS_RS09170
uniprot id: H8XUL0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1094466:KQS RS07405
gene id: 1094466:KQS_RS07405
uniprot id: H8XR03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS13390
gene id: 1094466:KQS_RS13390
uniprot id: H8XS08
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS12410
gene id: 1094466:KQS_RS12410
uniprot id: H8XRH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1094466:KQS RS00725
gene id: 1094466:KQS_RS00725
uniprot id: H8XNM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1094466:KQS RS09255
gene id: 1094466:KQS_RS09255
uniprot id: H8XUM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1094466:KQS RS00775
gene id: 1094466:KQS_RS00775
uniprot id: H8XNN9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS06905
gene id: 1094466:KQS_RS06905
uniprot id: H8XQQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1094466:KQS RS02010
gene id: 1094466:KQS_RS02010
uniprot id: H8XQA2
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1094466:KQS RS10050
gene id: 1094466:KQS_RS10050
uniprot id: H8XVJ7
names: Similarity
messages: Belongs to the CinA family.

1094466:KQS RS03340
gene id: 1094466:KQS_RS03340
uniprot id: H8XT62
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1094466:KQS RS00045
gene id: 1094466:KQS_RS00045
uniprot id: H8XNA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1094466:KQS RS11455
gene id: 1094466:KQS_RS11455
uniprot id: H8XQ11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1094466:KQS RS06490
gene id: 1094466:KQS_RS06490
uniprot id: H8XPJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS12430
gene id: 1094466:KQS_RS12430
uniprot id: H8XRH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1094466:KQS RS10185
gene id: 1094466:KQS_RS10185
uniprot id: H8XVM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1094466:KQS RS03135
gene id: 1094466:KQS_RS03135
uniprot id: H8XSN3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1094466:KQS RS12580
gene id: 1094466:KQS_RS12580
uniprot id: H8XRK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1094466:KQS RS03395
gene id: 1094466:KQS_RS03395
uniprot id: H8XT73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1094466:KQS RS12120
gene id: 1094466:KQS_RS12120
uniprot id: H8XRB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1094466:KQS RS06920
gene id: 1094466:KQS_RS06920
uniprot id: H8XQQ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS06470
gene id: 1094466:KQS_RS06470
uniprot id: H8XPI9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS08685
gene id: 1094466:KQS_RS08685
uniprot id: H8XTW4
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS10670
gene id: 1094466:KQS_RS10670
uniprot id: H8XVW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1094466:KQS RS01855
gene id: 1094466:KQS_RS01855
uniprot id: H8XQ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1094466:KQS RS06665
gene id: 1094466:KQS_RS06665
uniprot id: H8XQK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1094466:KQS RS02400
gene id: 1094466:KQS_RS02400
uniprot id: H8XQI0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1094466:KQS RS02195
gene id: 1094466:KQS_RS02195
uniprot id: H8XQD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1094466:KQS RS10285
gene id: 1094466:KQS_RS10285
uniprot id: H8XVP4
names: Similarity
messages: Belongs to the DinB family.

1094466:KQS RS00070
gene id: 1094466:KQS_RS00070
uniprot id: H8XNB2
names: Similarity
messages: Belongs to the Skp family.

1094466:KQS RS10515
gene id: 1094466:KQS_RS10515
uniprot id: H8XVT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1094466:KQS RS06305
gene id: 1094466:KQS_RS06305
uniprot id: H8XPF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1094466:KQS RS05785
gene id: 1094466:KQS_RS05785
uniprot id: H8XP59
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.

1094466:KQS RS01955
gene id: 1094466:KQS_RS01955
uniprot id: H8XQ91
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS03580
gene id: 1094466:KQS_RS03580
uniprot id: H8XTB0
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1094466:KQS RS12745
gene id: 1094466:KQS_RS12745
uniprot id: H8XRN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1094466:KQS RS13730
gene id: 1094466:KQS_RS13730
uniprot id: H8XS76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1094466:KQS RS01980
gene id: 1094466:KQS_RS01980
uniprot id: H8XQ96
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS00245
gene id: 1094466:KQS_RS00245
uniprot id: H8XNE6
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1094466:KQS RS13735
gene id: 1094466:KQS_RS13735
uniprot id: H8XS77
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1094466:KQS RS02870
gene id: 1094466:KQS_RS02870
uniprot id: H8XSI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1094466:KQS RS05375
gene id: 1094466:KQS_RS05375
uniprot id: H8XV84
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1094466:KQS RS00460
gene id: 1094466:KQS_RS00460
uniprot id: H8XNI5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1094466:KQS RS01950
gene id: 1094466:KQS_RS01950
uniprot id: H8XQ90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1094466:KQS RS03065
gene id: 1094466:KQS_RS03065
uniprot id: H8XSL9
names: Similarity
messages: Belongs to the Dps family.

1094466:KQS RS11875
gene id: 1094466:KQS_RS11875
uniprot id: H8XR70
names: Similarity
messages: Belongs to the fabD family.

1094466:KQS RS12830
gene id: 1094466:KQS_RS12830
uniprot id: H8XRQ2
names: Similarity
messages: Belongs to the histone deacetylase family.

1094466:KQS RS13450
gene id: 1094466:KQS_RS13450
uniprot id: H8XS20
names: Similarity
messages: Belongs to the pyruvate kinase family.

1094466:KQS RS08580
gene id: 1094466:KQS_RS08580
uniprot id: H8XTU4
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS03835
gene id: 1094466:KQS_RS03835
uniprot id: H8XTG0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1094466:KQS RS10010
gene id: 1094466:KQS_RS10010
uniprot id: H8XVI8
names: Similarity
messages: Belongs to the arginase family.

1094466:KQS RS02130
gene id: 1094466:KQS_RS02130
uniprot id: H8XQC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1094466:KQS RS04510
gene id: 1094466:KQS_RS04510
uniprot id: H8XU98
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1094466:KQS RS07325
gene id: 1094466:KQS_RS07325
uniprot id: H8XQY7
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS10435
gene id: 1094466:KQS_RS10435
uniprot id: H8XVS1
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1094466:KQS RS01800
gene id: 1094466:KQS_RS01800
uniprot id: H8XQ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1094466:KQS RS05415
gene id: 1094466:KQS_RS05415
uniprot id: H8XV92
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS11735
gene id: 1094466:KQS_RS11735
uniprot id: H8XR40
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1094466:KQS RS09955
gene id: 1094466:KQS_RS09955
uniprot id: H8XVH7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1094466:KQS RS12685
gene id: 1094466:KQS_RS12685
uniprot id: H8XRM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1094466:KQS RS12390
gene id: 1094466:KQS_RS12390
uniprot id: H8XRG7
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1094466:KQS RS03615
gene id: 1094466:KQS_RS03615
uniprot id: H8XTB7
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1094466:KQS RS05430
gene id: 1094466:KQS_RS05430
uniprot id: H8XV95
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1094466:KQS RS07265
gene id: 1094466:KQS_RS07265
uniprot id: H8XQX5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1094466:KQS RS03625
gene id: 1094466:KQS_RS03625
uniprot id: H8XTB9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1094466:KQS RS11500
gene id: 1094466:KQS_RS11500
uniprot id: H8XQ20
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1094466:KQS RS00135
gene id: 1094466:KQS_RS00135
uniprot id: H8XNC5
names: Similarity
messages: Belongs to the peptidase S41A family.

1094466:KQS RS04425
gene id: 1094466:KQS_RS04425
uniprot id: H8XU86
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS12270
gene id: 1094466:KQS_RS12270
uniprot id: H8XRE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1094466:KQS RS07770
gene id: 1094466:KQS_RS07770
uniprot id: H8XSX2
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1094466:KQS RS09060
gene id: 1094466:KQS_RS09060
uniprot id: H8XUI8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1094466:KQS RS11900
gene id: 1094466:KQS_RS11900
uniprot id: H8XR75
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1094466:KQS RS11430
gene id: 1094466:KQS_RS11430
uniprot id: H8XQ06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

1094466:KQS RS00555
gene id: 1094466:KQS_RS00555
uniprot id: H8XNK3
names: Similarity
messages: Belongs to the argonaute family. Long pAgo subfamily.

1094466:KQS RS13780
gene id: 1094466:KQS_RS13780
uniprot id: H8XS86
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1094466:KQS RS05330
gene id: 1094466:KQS_RS05330
uniprot id: H8XV75
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1094466:KQS RS12940
gene id: 1094466:KQS_RS12940
uniprot id: H8XRS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1094466:KQS RS09555
gene id: 1094466:KQS_RS09555
uniprot id: H8XUT4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1094466:KQS RS04190
gene id: 1094466:KQS_RS04190
uniprot id: H8XU40
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1094466:KQS RS10430
gene id: 1094466:KQS_RS10430
uniprot id: H8XVS0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1094466:KQS RS07205
gene id: 1094466:KQS_RS07205
uniprot id: H8XQW3
names: Similarity
messages: Belongs to the TrpF family.

1094466:KQS RS13860
gene id: 1094466:KQS_RS13860
uniprot id: H8XSA1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1094466:KQS RS08480
gene id: 1094466:KQS_RS08480
uniprot id: H8XTS4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1094466:KQS RS10135
gene id: 1094466:KQS_RS10135
uniprot id: H8XVL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

1094466:KQS RS01105
gene id: 1094466:KQS_RS01105
uniprot id: H8XNV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1094466:KQS RS09780
gene id: 1094466:KQS_RS09780
uniprot id: H8XUX7
names: Similarity
messages: Belongs to the isochorismate synthase family.

1094466:KQS RS06970
gene id: 1094466:KQS_RS06970
uniprot id: H8XQR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1094466:KQS RS10275
gene id: 1094466:KQS_RS10275
uniprot id: H8XVP2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1094466:KQS RS05395
gene id: 1094466:KQS_RS05395
uniprot id: H8XV88
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1094466:KQS RS02750
gene id: 1094466:KQS_RS02750
uniprot id: H8XSF9
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS10650
gene id: 1094466:KQS_RS10650
uniprot id: H8XVW4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1094466:KQS RS12440
gene id: 1094466:KQS_RS12440
uniprot id: H8XRH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS13625
gene id: 1094466:KQS_RS13625
uniprot id: H8XS55
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1094466:KQS RS06995
gene id: 1094466:KQS_RS06995
uniprot id: H8XQS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1094466:KQS RS08665
gene id: 1094466:KQS_RS08665
uniprot id: H8XTW0
names: Similarity
messages: Belongs to the MQO family.

1094466:KQS RS13655
gene id: 1094466:KQS_RS13655
uniprot id: H8XS61
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1094466:KQS RS09485
gene id: 1094466:KQS_RS09485
uniprot id: H8XUS2
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS09205
gene id: 1094466:KQS_RS09205
uniprot id: H8XUL7
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS08825
gene id: 1094466:KQS_RS08825
uniprot id: H8XTZ1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1094466:KQS RS06575
gene id: 1094466:KQS_RS06575
uniprot id: H8XPL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1094466:KQS RS05560
gene id: 1094466:KQS_RS05560
uniprot id: H8XVB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1094466:KQS RS11755
gene id: 1094466:KQS_RS11755
uniprot id: H8XR44
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1094466:KQS RS06760
gene id: 1094466:KQS_RS06760
uniprot id: H8XQM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1094466:KQS RS02835
gene id: 1094466:KQS_RS02835
uniprot id: H8XSH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1094466:KQS RS02990
gene id: 1094466:KQS_RS02990
uniprot id: H8XSK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1094466:KQS RS01165
gene id: 1094466:KQS_RS01165
uniprot id: H8XNW4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1094466:KQS RS07875
gene id: 1094466:KQS_RS07875
uniprot id: H8XSZ3
names: Similarity
messages: Belongs to the AHA1 family.

1094466:KQS RS01030
gene id: 1094466:KQS_RS01030
uniprot id: H8XNT7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1094466:KQS RS01215
gene id: 1094466:KQS_RS01215
uniprot id: H8XNX4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1094466:KQS RS09795
gene id: 1094466:KQS_RS09795
uniprot id: H8XUY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1094466:KQS RS05095
gene id: 1094466:KQS_RS05095
uniprot id: H8XV28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1094466:KQS RS02855
gene id: 1094466:KQS_RS02855
uniprot id: H8XSI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1094466:KQS RS00740
gene id: 1094466:KQS_RS00740
uniprot id: H8XNN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1094466:KQS RS03325
gene id: 1094466:KQS_RS03325
uniprot id: H8XT59
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1094466:KQS RS03885
gene id: 1094466:KQS_RS03885
uniprot id: H8XTG5
names: Similarity
messages: Belongs to the NusB family.

1094466:KQS RS03965
gene id: 1094466:KQS_RS03965
uniprot id: H8XTI1
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1094466:KQS RS02790
gene id: 1094466:KQS_RS02790
uniprot id: H8XSG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1094466:KQS RS13495
gene id: 1094466:KQS_RS13495
uniprot id: H8XS29
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1094466:KQS RS08225
gene id: 1094466:KQS_RS08225
uniprot id: H8XTM4
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1094466:KQS RS12355
gene id: 1094466:KQS_RS12355
uniprot id: H8XRG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS07020
gene id: 1094466:KQS_RS07020
uniprot id: H8XQS6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1094466:KQS RS12335
gene id: 1094466:KQS_RS12335
uniprot id: H8XRF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1094466:KQS RS02695
gene id: 1094466:KQS_RS02695
uniprot id: H8XSE8
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

1094466:KQS RS01150
gene id: 1094466:KQS_RS01150
uniprot id: H8XNW1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1094466:KQS RS04075
gene id: 1094466:KQS_RS04075
uniprot id: H8XTK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1094466:KQS RS00005
gene id: 1094466:KQS_RS00005
uniprot id: H8XNA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1094466:KQS RS02535
gene id: 1094466:KQS_RS02535
uniprot id: H8XSB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1094466:KQS RS09525
gene id: 1094466:KQS_RS09525
uniprot id: H8XUT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1094466:KQS RS10645
gene id: 1094466:KQS_RS10645
uniprot id: H8XVW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1094466:KQS RS02390
gene id: 1094466:KQS_RS02390
uniprot id: H8XQH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS10525
gene id: 1094466:KQS_RS10525
uniprot id: H8XVT9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1094466:KQS RS11485
gene id: 1094466:KQS_RS11485
uniprot id: H8XQ17
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1094466:KQS RS05770
gene id: 1094466:KQS_RS05770
uniprot id: H8XP56
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS07905
gene id: 1094466:KQS_RS07905
uniprot id: H8XSZ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1094466:KQS RS04525
gene id: 1094466:KQS_RS04525
uniprot id: H8XUA1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1094466:KQS RS07790
gene id: 1094466:KQS_RS07790
uniprot id: H8XSX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1094466:KQS RS09625
gene id: 1094466:KQS_RS09625
uniprot id: H8XUU8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1094466:KQS RS07330
gene id: 1094466:KQS_RS07330
uniprot id: H8XQY8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1094466:KQS RS02780
gene id: 1094466:KQS_RS02780
uniprot id: H8XSG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1094466:KQS RS11135
gene id: 1094466:KQS_RS11135
uniprot id: H8XPV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1094466:KQS RS02925
gene id: 1094466:KQS_RS02925
uniprot id: H8XSJ6
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1094466:KQS RS03170
gene id: 1094466:KQS_RS03170
uniprot id: H8XSP0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1094466:KQS RS12930
gene id: 1094466:KQS_RS12930
uniprot id: H8XRS1
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS01515
gene id: 1094466:KQS_RS01515
uniprot id: H8XP31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1094466:KQS RS02365
gene id: 1094466:KQS_RS02365
uniprot id: H8XQH3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1094466:KQS RS12485
gene id: 1094466:KQS_RS12485
uniprot id: H8XRI6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1094466:KQS RS00665
gene id: 1094466:KQS_RS00665
uniprot id: H8XNL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

1094466:KQS RS05450
gene id: 1094466:KQS_RS05450
uniprot id: H8XV99
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS13440
gene id: 1094466:KQS_RS13440
uniprot id: H8XS18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1094466:KQS RS05130
gene id: 1094466:KQS_RS05130
uniprot id: H8XV35
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1094466:KQS RS13260
gene id: 1094466:KQS_RS13260
uniprot id: H8XRY2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS09085
gene id: 1094466:KQS_RS09085
uniprot id: H8XUJ3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1094466:KQS RS08790
gene id: 1094466:KQS_RS08790
uniprot id: H8XTY4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS07200
gene id: 1094466:KQS_RS07200
uniprot id: H8XQW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1094466:KQS RS02905
gene id: 1094466:KQS_RS02905
uniprot id: H8XSJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1094466:KQS RS12510
gene id: 1094466:KQS_RS12510
uniprot id: H8XRJ1
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS11445
gene id: 1094466:KQS_RS11445
uniprot id: H8XQ09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS07180
gene id: 1094466:KQS_RS07180
uniprot id: H8XQV8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1094466:KQS RS01845
gene id: 1094466:KQS_RS01845
uniprot id: H8XQ69
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1094466:KQS RS00455
gene id: 1094466:KQS_RS00455
uniprot id: H8XNI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1094466:KQS RS01820
gene id: 1094466:KQS_RS01820
uniprot id: H8XQ64
names: Similarity
messages: Belongs to the SCO1/2 family.

1094466:KQS RS11995
gene id: 1094466:KQS_RS11995
uniprot id: H8XR91
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1094466:KQS RS09125
gene id: 1094466:KQS_RS09125
uniprot id: H8XUK1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1094466:KQS RS11920
gene id: 1094466:KQS_RS11920
uniprot id: H8XR79
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

1094466:KQS RS01065
gene id: 1094466:KQS_RS01065
uniprot id: H8XNU4
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS10485
gene id: 1094466:KQS_RS10485
uniprot id: H8XVT1
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS04990
gene id: 1094466:KQS_RS04990
uniprot id: H8XV02
names: Similarity
messages: Belongs to the UPF0166 family.

1094466:KQS RS09700
gene id: 1094466:KQS_RS09700
uniprot id: H8XUW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1094466:KQS RS05660
gene id: 1094466:KQS_RS05660
uniprot id: H8XVD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1094466:KQS RS06525
gene id: 1094466:KQS_RS06525
uniprot id: H8XPK0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1094466:KQS RS06355
gene id: 1094466:KQS_RS06355
uniprot id: H8XPG6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS10655
gene id: 1094466:KQS_RS10655
uniprot id: H8XVW5
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1094466:KQS RS06365
gene id: 1094466:KQS_RS06365
uniprot id: H8XPG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1094466:KQS RS07435
gene id: 1094466:KQS_RS07435
uniprot id: H8XR09
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1094466:KQS RS04665
gene id: 1094466:KQS_RS04665
uniprot id: H8XUC6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1094466:KQS RS02680
gene id: 1094466:KQS_RS02680
uniprot id: H8XSE5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1094466:KQS RS13115
gene id: 1094466:KQS_RS13115
uniprot id: H8XRV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

1094466:KQS RS08660
gene id: 1094466:KQS_RS08660
uniprot id: H8XTV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1094466:KQS RS01580
gene id: 1094466:KQS_RS01580
uniprot id: H8XP43
names: Similarity
messages: Belongs to the universal stress protein A family.

1094466:KQS RS08475
gene id: 1094466:KQS_RS08475
uniprot id: H8XTS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1094466:KQS RS08180
gene id: 1094466:KQS_RS08180
uniprot id: H8XT53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

1094466:KQS RS01880
gene id: 1094466:KQS_RS01880
uniprot id: H8XQ76
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1094466:KQS RS02240
gene id: 1094466:KQS_RS02240
uniprot id: H8XQE8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1094466:KQS RS03125
gene id: 1094466:KQS_RS03125
uniprot id: H8XSN1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1094466:KQS RS12095
gene id: 1094466:KQS_RS12095
uniprot id: H8XRB1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1094466:KQS RS07305
gene id: 1094466:KQS_RS07305
uniprot id: H8XQY3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS00800
gene id: 1094466:KQS_RS00800
uniprot id: H8XNP4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1094466:KQS RS13015
gene id: 1094466:KQS_RS13015
uniprot id: H8XRT4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1094466:KQS RS06480
gene id: 1094466:KQS_RS06480
uniprot id: H8XPJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1094466:KQS RS05570
gene id: 1094466:KQS_RS05570
uniprot id: H8XVC0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1094466:KQS RS02885
gene id: 1094466:KQS_RS02885
uniprot id: H8XSI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1094466:KQS RS01920
gene id: 1094466:KQS_RS01920
uniprot id: H8XQ84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS11170
gene id: 1094466:KQS_RS11170
uniprot id: H8XPV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1094466:KQS RS00805
gene id: 1094466:KQS_RS00805
uniprot id: H8XNP5
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1094466:KQS RS12570
gene id: 1094466:KQS_RS12570
uniprot id: H8XRK2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1094466:KQS RS02510
gene id: 1094466:KQS_RS02510
uniprot id: H8XSB0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1094466:KQS RS12750
gene id: 1094466:KQS_RS12750
uniprot id: H8XRN8
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1094466:KQS RS02875
gene id: 1094466:KQS_RS02875
uniprot id: H8XSI5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1094466:KQS RS03775
gene id: 1094466:KQS_RS03775
uniprot id: H8XTE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1094466:KQS RS08950
gene id: 1094466:KQS_RS08950
uniprot id: H8XU14
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

1094466:KQS RS10495
gene id: 1094466:KQS_RS10495
uniprot id: H8XVT3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1094466:KQS RS06725
gene id: 1094466:KQS_RS06725
uniprot id: H8XQL5
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1094466:KQS RS13715
gene id: 1094466:KQS_RS13715
uniprot id: H8XS73
names: Similarity
messages: Belongs to the GARS family.

1094466:KQS RS02775
gene id: 1094466:KQS_RS02775
uniprot id: H8XSG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1094466:KQS RS12815
gene id: 1094466:KQS_RS12815
uniprot id: H8XRP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1094466:KQS RS09330
gene id: 1094466:KQS_RS09330
uniprot id: H8XUP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1094466:KQS RS04650
gene id: 1094466:KQS_RS04650
uniprot id: H8XUC3
names: Similarity
messages: Belongs to the HSP15 family.

1094466:KQS RS03300
gene id: 1094466:KQS_RS03300
uniprot id: H8XSR6
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1094466:KQS RS06295
gene id: 1094466:KQS_RS06295
uniprot id: H8XPF4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1094466:KQS RS02940
gene id: 1094466:KQS_RS02940
uniprot id: H8XSJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1094466:KQS RS02650
gene id: 1094466:KQS_RS02650
uniprot id: H8XSD8
names: Similarity
messages: Belongs to the peptidase M4 family.

1094466:KQS RS07250
gene id: 1094466:KQS_RS07250
uniprot id: H8XQX2
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

1094466:KQS RS05385
gene id: 1094466:KQS_RS05385
uniprot id: H8XV86
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS02180
gene id: 1094466:KQS_RS02180
uniprot id: H8XQD6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1094466:KQS RS01240
gene id: 1094466:KQS_RS01240
uniprot id: H8XNX9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS01985
gene id: 1094466:KQS_RS01985
uniprot id: H8XQ97
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1094466:KQS RS02655
gene id: 1094466:KQS_RS02655
uniprot id: H8XSD9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1094466:KQS RS02935
gene id: 1094466:KQS_RS02935
uniprot id: H8XSJ8
names: Similarity
messages: Belongs to the citrate synthase family.

1094466:KQS RS02555
gene id: 1094466:KQS_RS02555
uniprot id: H8XSB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1094466:KQS RS12885
gene id: 1094466:KQS_RS12885
uniprot id: H8XRR2
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1094466:KQS RS08915
gene id: 1094466:KQS_RS08915
uniprot id: H8XU07
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS01885
gene id: 1094466:KQS_RS01885
uniprot id: H8XQ77
names: Similarity
messages: Belongs to the Skp family.

1094466:KQS RS00180
gene id: 1094466:KQS_RS00180
uniprot id: H8XND3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1094466:KQS RS08640
gene id: 1094466:KQS_RS08640
uniprot id: H8XTV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1094466:KQS RS00975
gene id: 1094466:KQS_RS00975
uniprot id: H8XNS5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1094466:KQS RS12670
gene id: 1094466:KQS_RS12670
uniprot id: H8XRM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1094466:KQS RS12690
gene id: 1094466:KQS_RS12690
uniprot id: H8XRM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1094466:KQS RS02820
gene id: 1094466:KQS_RS02820
uniprot id: H8XSH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1094466:KQS RS01355
gene id: 1094466:KQS_RS01355
uniprot id: H8XP01
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1094466:KQS RS12505
gene id: 1094466:KQS_RS12505
uniprot id: H8XRJ0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1094466:KQS RS00140
gene id: 1094466:KQS_RS00140
uniprot id: H8XNC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1094466:KQS RS10530
gene id: 1094466:KQS_RS10530
uniprot id: H8XVU0
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS09585
gene id: 1094466:KQS_RS09585
uniprot id: H8XUU0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1094466:KQS RS06300
gene id: 1094466:KQS_RS06300
uniprot id: H8XPF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1094466:KQS RS00185
gene id: 1094466:KQS_RS00185
uniprot id: H8XND4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1094466:KQS RS00380
gene id: 1094466:KQS_RS00380
uniprot id: H8XNH2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1094466:KQS RS07900
gene id: 1094466:KQS_RS07900
uniprot id: H8XSZ8
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1094466:KQS RS07870
gene id: 1094466:KQS_RS07870
uniprot id: H8XSZ2
names: Similarity
messages: Belongs to the AHA1 family.

1094466:KQS RS11140
gene id: 1094466:KQS_RS11140
uniprot id: H8XPV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1094466:KQS RS07910
gene id: 1094466:KQS_RS07910
uniprot id: H8XT00
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1094466:KQS RS06610
gene id: 1094466:KQS_RS06610
uniprot id: H8XPL6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS12360
gene id: 1094466:KQS_RS12360
uniprot id: H8XRG1
names: Subcellular Location Annotation
messages: Cytoplasm

1094466:KQS RS02690
gene id: 1094466:KQS_RS02690
uniprot id: H8XSE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1094466:KQS RS06200
gene id: 1094466:KQS_RS06200
uniprot id: H8XPD5
names: Similarity
messages: Belongs to the CvfB family.

1094466:KQS RS06150
gene id: 1094466:KQS_RS06150
uniprot id: H8XPC8
names: Similarity
messages: Belongs to the peptidase C40 family.

1094466:KQS RS13395
gene id: 1094466:KQS_RS13395
uniprot id: H8XS09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1094466:KQS RS02145
gene id: 1094466:KQS_RS02145
uniprot id: H8XQC9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1094466:KQS RS07290
gene id: 1094466:KQS_RS07290
uniprot id: H8XQY0
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS12595
gene id: 1094466:KQS_RS12595
uniprot id: H8XRK7
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1094466:KQS RS01690
gene id: 1094466:KQS_RS01690
uniprot id: H8XQ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1094466:KQS RS06375
gene id: 1094466:KQS_RS06375
uniprot id: H8XPH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1094466:KQS RS10770
gene id: 1094466:KQS_RS10770
uniprot id: H8XPN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1094466:KQS RS06830
gene id: 1094466:KQS_RS06830
uniprot id: H8XQN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1094466:KQS RS02170
gene id: 1094466:KQS_RS02170
uniprot id: H8XQD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1094466:KQS RS02900
gene id: 1094466:KQS_RS02900
uniprot id: H8XSJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1094466:KQS RS01050
gene id: 1094466:KQS_RS01050
uniprot id: H8XNU1
names: Similarity
messages: Belongs to the SusD family.

1094466:KQS RS05230
gene id: 1094466:KQS_RS05230
uniprot id: H8XV55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1094466:KQS RS03345
gene id: 1094466:KQS_RS03345
uniprot id: H8XT63
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS04565
gene id: 1094466:KQS_RS04565
uniprot id: H8XUA9
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1094466:KQS RS05525
gene id: 1094466:KQS_RS05525
uniprot id: H8XVB1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1094466:KQS RS07070
gene id: 1094466:KQS_RS07070
uniprot id: H8XQT5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1094466:KQS RS04115
gene id: 1094466:KQS_RS04115
uniprot id: H8XTL1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1094466:KQS RS01070
gene id: 1094466:KQS_RS01070
uniprot id: H8XNU5
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1094466:KQS RS02800
gene id: 1094466:KQS_RS02800
uniprot id: H8XSH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1094466:KQS RS00660
gene id: 1094466:KQS_RS00660
uniprot id: H8XNL6
names: Subunit
messages: Homodimer.

1094466:KQS RS13080
gene id: 1094466:KQS_RS13080
uniprot id: H8XRU6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1094466:KQS RS02945
gene id: 1094466:KQS_RS02945
uniprot id: H8XSK0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS03760
gene id: 1094466:KQS_RS03760
uniprot id: H8XTE5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1094466:KQS RS03585
gene id: 1094466:KQS_RS03585
uniprot id: H8XTB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1094466:KQS RS13855
gene id: 1094466:KQS_RS13855
uniprot id: H8XSA0
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS05615
gene id: 1094466:KQS_RS05615
uniprot id: H8XVC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS04360
gene id: 1094466:KQS_RS04360
uniprot id: H8XU74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1094466:KQS RS04175
gene id: 1094466:KQS_RS04175
uniprot id: H8XU37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1094466:KQS RS06345
gene id: 1094466:KQS_RS06345
uniprot id: H8XPG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1094466:KQS RS02025
gene id: 1094466:KQS_RS02025
uniprot id: H8XQA5
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS00025
gene id: 1094466:KQS_RS00025
uniprot id: H8XNA3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1094466:KQS RS13370
gene id: 1094466:KQS_RS13370
uniprot id: H8XS04
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS02785
gene id: 1094466:KQS_RS02785
uniprot id: H8XSG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1094466:KQS RS02795
gene id: 1094466:KQS_RS02795
uniprot id: H8XSG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1094466:KQS RS09355
gene id: 1094466:KQS_RS09355
uniprot id: H8XUP7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1094466:KQS RS10835
gene id: 1094466:KQS_RS10835
uniprot id: H8XPP5
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1094466:KQS RS12840
gene id: 1094466:KQS_RS12840
uniprot id: H8XRQ4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS13240
gene id: 1094466:KQS_RS13240
uniprot id: H8XRX8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1094466:KQS RS09335
gene id: 1094466:KQS_RS09335
uniprot id: H8XUP3
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1094466:KQS RS04255
gene id: 1094466:KQS_RS04255
uniprot id: H8XU53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1094466:KQS RS12375
gene id: 1094466:KQS_RS12375
uniprot id: H8XRG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1094466:KQS RS11460
gene id: 1094466:KQS_RS11460
uniprot id: H8XQ12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

1094466:KQS RS03590
gene id: 1094466:KQS_RS03590
uniprot id: H8XTB2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1094466:KQS RS03210
gene id: 1094466:KQS_RS03210
uniprot id: H8XSP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

1094466:KQS RS10695
gene id: 1094466:KQS_RS10695
uniprot id: H8XVW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1094466:KQS RS13500
gene id: 1094466:KQS_RS13500
uniprot id: H8XS30
names: Similarity
messages: Belongs to the group II decarboxylase family.

1094466:KQS RS02530
gene id: 1094466:KQS_RS02530
uniprot id: H8XSB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1094466:KQS RS00970
gene id: 1094466:KQS_RS00970
uniprot id: H8XNS4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1094466:KQS RS02815
gene id: 1094466:KQS_RS02815
uniprot id: H8XSH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1094466:KQS RS01685
gene id: 1094466:KQS_RS01685
uniprot id: H8XQ37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1094466:KQS RS03985
gene id: 1094466:KQS_RS03985
uniprot id: H8XTI5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1094466:KQS RS05380
gene id: 1094466:KQS_RS05380
uniprot id: H8XV85
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1094466:KQS RS03565
gene id: 1094466:KQS_RS03565
uniprot id: H8XTA7
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1094466:KQS RS02285
gene id: 1094466:KQS_RS02285
uniprot id: H8XQF7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1094466:KQS RS02150
gene id: 1094466:KQS_RS02150
uniprot id: H8XQD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1094466:KQS RS09400
gene id: 1094466:KQS_RS09400
uniprot id: H8XUQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1094466:KQS RS06895
gene id: 1094466:KQS_RS06895
uniprot id: H8XQQ1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1094466:KQS RS02675
gene id: 1094466:KQS_RS02675
uniprot id: H8XSE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1094466:KQS RS10320
gene id: 1094466:KQS_RS10320
uniprot id: H8XVQ1
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1094466:KQS RS00270
gene id: 1094466:KQS_RS00270
uniprot id: H8XNF1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1094466:KQS RS10885
gene id: 1094466:KQS_RS10885
uniprot id: H8XPQ5
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1094466:KQS RS04705
gene id: 1094466:KQS_RS04705
uniprot id: H8XUD4
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1094466:KQS RS07195
gene id: 1094466:KQS_RS07195
uniprot id: H8XQW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1094466:KQS RS01250
gene id: 1094466:KQS_RS01250
uniprot id: H8XNY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1094466:KQS RS06615
gene id: 1094466:KQS_RS06615
uniprot id: H8XPL7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1094466:KQS RS10490
gene id: 1094466:KQS_RS10490
uniprot id: H8XVT2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1094466:KQS RS13550
gene id: 1094466:KQS_RS13550
uniprot id: H8XS40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1094466:KQS RS10700
gene id: 1094466:KQS_RS10700
uniprot id: H8XVX0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1094466:KQS RS06340
gene id: 1094466:KQS_RS06340
uniprot id: H8XPG3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1094466:KQS RS00145
gene id: 1094466:KQS_RS00145
uniprot id: H8XNC7
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1094466:KQS RS08520
gene id: 1094466:KQS_RS08520
uniprot id: H8XTT2
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1094466:KQS RS02115
gene id: 1094466:KQS_RS02115
uniprot id: H8XQC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1094466:KQS RS03910
gene id: 1094466:KQS_RS03910
uniprot id: H8XTH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1094466:KQS RS02715
gene id: 1094466:KQS_RS02715
uniprot id: H8XSF2
names: Similarity
messages: Belongs to the UPF0758 family.

1094466:KQS RS01710
gene id: 1094466:KQS_RS01710
uniprot id: H8XQ42
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1094466:KQS RS11175
gene id: 1094466:KQS_RS11175
uniprot id: H8XPW0
names: Similarity
messages: Belongs to the arginase family.

1094466:KQS RS13465
gene id: 1094466:KQS_RS13465
uniprot id: H8XS23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1094466:KQS RS10460
gene id: 1094466:KQS_RS10460
uniprot id: H8XVS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1094466:KQS RS07825
gene id: 1094466:KQS_RS07825
uniprot id: H8XSY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1094466:KQS RS01805
gene id: 1094466:KQS_RS01805
uniprot id: H8XQ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

1094466:KQS RS09320
gene id: 1094466:KQS_RS09320
uniprot id: H8XUP0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1094466:KQS RS11450
gene id: 1094466:KQS_RS11450
uniprot id: H8XQ10
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS03410
gene id: 1094466:KQS_RS03410
uniprot id: H8XT76
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS06320
gene id: 1094466:KQS_RS06320
uniprot id: H8XPF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1094466:KQS RS03960
gene id: 1094466:KQS_RS03960
uniprot id: H8XTI0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1094466:KQS RS13830
gene id: 1094466:KQS_RS13830
uniprot id: H8XS96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1094466:KQS RS03255
gene id: 1094466:KQS_RS03255
uniprot id: H8XSQ7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1094466:KQS RS04495
gene id: 1094466:KQS_RS04495
uniprot id: H8XU95
names: Similarity
messages: Belongs to the CarB family.

1094466:KQS RS00735
gene id: 1094466:KQS_RS00735
uniprot id: H8XNN1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1094466:KQS RS05535
gene id: 1094466:KQS_RS05535
uniprot id: H8XVB3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1094466:KQS RS04250
gene id: 1094466:KQS_RS04250
uniprot id: H8XU52
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1094466:KQS RS02250
gene id: 1094466:KQS_RS02250
uniprot id: H8XQF0
names: Similarity
messages: Belongs to the asparagine synthetase family.

1094466:KQS RS12080
gene id: 1094466:KQS_RS12080
uniprot id: H8XRA8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1094466:KQS RS01840
gene id: 1094466:KQS_RS01840
uniprot id: H8XQ68
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1094466:KQS RS06330
gene id: 1094466:KQS_RS06330
uniprot id: H8XPG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1094466:KQS RS09675
gene id: 1094466:KQS_RS09675
uniprot id: H8XUV8
names: Cofactor
messages: Can also use Mn(2+) ion.

1094466:KQS RS06405
gene id: 1094466:KQS_RS06405
uniprot id: H8XPH6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1094466:KQS RS04205
gene id: 1094466:KQS_RS04205
uniprot id: H8XU43
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1094466:KQS RS02920
gene id: 1094466:KQS_RS02920
uniprot id: H8XSJ5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1094466:KQS RS06790
gene id: 1094466:KQS_RS06790
uniprot id: H8XQM9
names: Similarity
messages: Belongs to the SUI1 family.

1094466:KQS RS01765
gene id: 1094466:KQS_RS01765
uniprot id: H8XQ53
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1094466:KQS RS03730
gene id: 1094466:KQS_RS03730
uniprot id: H8XTD9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS04520
gene id: 1094466:KQS_RS04520
uniprot id: H8XUA0
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1094466:KQS RS09945
gene id: 1094466:KQS_RS09945
uniprot id: H8XVH5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1094466:KQS RS02305
gene id: 1094466:KQS_RS02305
uniprot id: H8XQG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1094466:KQS RS04315
gene id: 1094466:KQS_RS04315
uniprot id: H8XU65
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1094466:KQS RS05575
gene id: 1094466:KQS_RS05575
uniprot id: H8XVC1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1094466:KQS RS00195
gene id: 1094466:KQS_RS00195
uniprot id: H8XND6
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1094466:KQS RS00790
gene id: 1094466:KQS_RS00790
uniprot id: H8XNP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1094466:KQS RS09415
gene id: 1094466:KQS_RS09415
uniprot id: H8XUQ8
names: Similarity
messages: Belongs to the ArsC family.

1094466:KQS RS13800
gene id: 1094466:KQS_RS13800
uniprot id: H8XS90
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1094466:KQS RS13120
gene id: 1094466:KQS_RS13120
uniprot id: H8XRV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1094466:KQS RS04185
gene id: 1094466:KQS_RS04185
uniprot id: H8XU39
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1094466:KQS RS04610
gene id: 1094466:KQS_RS04610
uniprot id: H8XUB8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1094466:KQS RS11270
gene id: 1094466:KQS_RS11270
uniprot id: H8XPX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1094466:KQS RS03620
gene id: 1094466:KQS_RS03620
uniprot id: H8XTB8
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS02245
gene id: 1094466:KQS_RS02245
uniprot id: H8XQE9
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS12480
gene id: 1094466:KQS_RS12480
uniprot id: H8XRI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1094466:KQS RS09910
gene id: 1094466:KQS_RS09910
uniprot id: H8XVG8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS06600
gene id: 1094466:KQS_RS06600
uniprot id: H8XPL4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1094466:KQS RS03180
gene id: 1094466:KQS_RS03180
uniprot id: H8XSP2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1094466:KQS RS03385
gene id: 1094466:KQS_RS03385
uniprot id: H8XT71
names: Similarity
messages: Belongs to the asparagine synthetase family.

1094466:KQS RS07035
gene id: 1094466:KQS_RS07035
uniprot id: H8XQS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1094466:KQS RS09280
gene id: 1094466:KQS_RS09280
uniprot id: H8XUN2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1094466:KQS RS03605
gene id: 1094466:KQS_RS03605
uniprot id: H8XTB5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1094466:KQS RS10190
gene id: 1094466:KQS_RS10190
uniprot id: H8XVM5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1094466:KQS RS06555
gene id: 1094466:KQS_RS06555
uniprot id: H8XPK6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1094466:KQS RS04395
gene id: 1094466:KQS_RS04395
uniprot id: H8XU81
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1094466:KQS RS04505
gene id: 1094466:KQS_RS04505
uniprot id: H8XU97
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS10220
gene id: 1094466:KQS_RS10220
uniprot id: H8XVN1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1094466:KQS RS13520
gene id: 1094466:KQS_RS13520
uniprot id: H8XS34
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS12315
gene id: 1094466:KQS_RS12315
uniprot id: H8XRF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1094466:KQS RS05125
gene id: 1094466:KQS_RS05125
uniprot id: H8XV34
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.

1094466:KQS RS02385
gene id: 1094466:KQS_RS02385
uniprot id: H8XQH7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1094466:KQS RS00720
gene id: 1094466:KQS_RS00720
uniprot id: H8XNM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1094466:KQS RS06420
gene id: 1094466:KQS_RS06420
uniprot id: H8XPH9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1094466:KQS RS03250
gene id: 1094466:KQS_RS03250
uniprot id: H8XSQ6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1094466:KQS RS12055
gene id: 1094466:KQS_RS12055
uniprot id: H8XRA3
names: Similarity
messages: Belongs to the aspartokinase family.

1094466:KQS RS03695
gene id: 1094466:KQS_RS03695
uniprot id: H8XTD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1094466:KQS RS00115
gene id: 1094466:KQS_RS00115
uniprot id: H8XNC1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1094466:KQS RS03715
gene id: 1094466:KQS_RS03715
uniprot id: H8XTD6
names: Similarity
messages: Belongs to the DEAD box helicase family.

1094466:KQS RS07140
gene id: 1094466:KQS_RS07140
uniprot id: H8XQV0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1094466:KQS RS12790
gene id: 1094466:KQS_RS12790
uniprot id: H8XRP4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1094466:KQS RS10825
gene id: 1094466:KQS_RS10825
uniprot id: H8XPP3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1094466:KQS RS12780
gene id: 1094466:KQS_RS12780
uniprot id: H8XRP2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1094466:KQS RS10340
gene id: 1094466:KQS_RS10340
uniprot id: H8XVQ4
names: Subcellular Location Annotation
messages: Cytoplasm

1094466:KQS RS08930
gene id: 1094466:KQS_RS08930
uniprot id: H8XU10
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1094466:KQS RS02880
gene id: 1094466:KQS_RS02880
uniprot id: H8XSI6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1094466:KQS RS10040
gene id: 1094466:KQS_RS10040
uniprot id: H8XVJ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1094466:KQS RS12785
gene id: 1094466:KQS_RS12785
uniprot id: H8XRP3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1094466:KQS RS09015
gene id: 1094466:KQS_RS09015
uniprot id: H8XU27
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1094466:KQS RS04145
gene id: 1094466:KQS_RS04145
uniprot id: H8XU31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1094466:KQS RS06900
gene id: 1094466:KQS_RS06900
uniprot id: H8XQQ2
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1094466:KQS RS12950
gene id: 1094466:KQS_RS12950
uniprot id: H8XRS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1094466:KQS RS06495
gene id: 1094466:KQS_RS06495
uniprot id: H8XPJ4
names: Similarity
messages: Belongs to the peptidase S8 family.

1094466:KQS RS07925
gene id: 1094466:KQS_RS07925
uniprot id: H8XT04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1094466:KQS RS00900
gene id: 1094466:KQS_RS00900
uniprot id: H8XNR1
names: Similarity
messages: Belongs to the transposase 27 family.

1094466:KQS RS05495
gene id: 1094466:KQS_RS05495
uniprot id: H8XVA5
names: Similarity
messages: Belongs to the UPF0111 family.

1094466:KQS RS09175
gene id: 1094466:KQS_RS09175
uniprot id: H8XUL1
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS04080
gene id: 1094466:KQS_RS04080
uniprot id: H8XTK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1094466:KQS RS13525
gene id: 1094466:KQS_RS13525
uniprot id: H8XS35
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1094466:KQS RS04055
gene id: 1094466:KQS_RS04055
uniprot id: H8XTJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1094466:KQS RS04950
gene id: 1094466:KQS_RS04950
uniprot id: H8XUI1
names: Similarity
messages: Belongs to the UPF0166 family.

1094466:KQS RS12165
gene id: 1094466:KQS_RS12165
uniprot id: H8XRC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1094466:KQS RS04270
gene id: 1094466:KQS_RS04270
uniprot id: H8XU56
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS04050
gene id: 1094466:KQS_RS04050
uniprot id: H8XTJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1094466:KQS RS00255
gene id: 1094466:KQS_RS00255
uniprot id: H8XNE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1094466:KQS RS06135
gene id: 1094466:KQS_RS06135
uniprot id: H8XPC5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1094466:KQS RS08425
gene id: 1094466:KQS_RS08425
uniprot id: H8XTR4
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1094466:KQS RS02450
gene id: 1094466:KQS_RS02450
uniprot id: H8XQJ0
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1094466:KQS RS03160
gene id: 1094466:KQS_RS03160
uniprot id: H8XSN8
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1094466:KQS RS13475
gene id: 1094466:KQS_RS13475
uniprot id: H8XS25
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1094466:KQS RS05500
gene id: 1094466:KQS_RS05500
uniprot id: H8XVA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1094466:KQS RS10290
gene id: 1094466:KQS_RS10290
uniprot id: H8XVP5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1094466:KQS RS10225
gene id: 1094466:KQS_RS10225
uniprot id: H8XVN2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1094466:KQS RS12380
gene id: 1094466:KQS_RS12380
uniprot id: H8XRG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1094466:KQS RS02065
gene id: 1094466:KQS_RS02065
uniprot id: H8XQB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1094466:KQS RS01760
gene id: 1094466:KQS_RS01760
uniprot id: H8XQ52
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1094466:KQS RS13790
gene id: 1094466:KQS_RS13790
uniprot id: H8XS88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1094466:KQS RS07370
gene id: 1094466:KQS_RS07370
uniprot id: H8XQZ6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1094466:KQS RS03530
gene id: 1094466:KQS_RS03530
uniprot id: H8XTA0
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1094466:KQS RS02770
gene id: 1094466:KQS_RS02770
uniprot id: H8XSG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1094466:KQS RS12465
gene id: 1094466:KQS_RS12465
uniprot id: H8XRI2
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1094466:KQS RS10140
gene id: 1094466:KQS_RS10140
uniprot id: H8XVL5
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1094466:KQS RS01505
gene id: 1094466:KQS_RS01505
uniprot id: H8XP29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1094466:KQS RS11625
gene id: 1094466:KQS_RS11625
uniprot id: H8XR18
names: Similarity
messages: Belongs to the peptidase S51 family.

1094466:KQS RS00220
gene id: 1094466:KQS_RS00220
uniprot id: H8XNE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1094466:KQS RS13775
gene id: 1094466:KQS_RS13775
uniprot id: H8XS85
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS13285
gene id: 1094466:KQS_RS13285
uniprot id: H8XRY7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1094466:KQS RS05105
gene id: 1094466:KQS_RS05105
uniprot id: H8XV30
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1094466:KQS RS06450
gene id: 1094466:KQS_RS06450
uniprot id: H8XPI5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1094466:KQS RS13585
gene id: 1094466:KQS_RS13585
uniprot id: H8XS47
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1094466:KQS RS01910
gene id: 1094466:KQS_RS01910
uniprot id: H8XQ82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS13660
gene id: 1094466:KQS_RS13660
uniprot id: H8XS62
names: Similarity
messages: Belongs to the DprA/Smf family.

1094466:KQS RS02895
gene id: 1094466:KQS_RS02895
uniprot id: H8XSI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1094466:KQS RS02295
gene id: 1094466:KQS_RS02295
uniprot id: H8XQF9
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1094466:KQS RS00825
gene id: 1094466:KQS_RS00825
uniprot id: H8XNP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1094466:KQS RS06875
gene id: 1094466:KQS_RS06875
uniprot id: H8XQP7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1094466:KQS RS03945
gene id: 1094466:KQS_RS03945
uniprot id: H8XTH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

1094466:KQS RS04585
gene id: 1094466:KQS_RS04585
uniprot id: H8XUB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1094466:KQS RS12945
gene id: 1094466:KQS_RS12945
uniprot id: H8XRS4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1094466:KQS RS10385
gene id: 1094466:KQS_RS10385
uniprot id: H8XVR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1094466:KQS RS10815
gene id: 1094466:KQS_RS10815
uniprot id: H8XPP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1094466:KQS RS12370
gene id: 1094466:KQS_RS12370
uniprot id: H8XRG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1094466:KQS RS06445
gene id: 1094466:KQS_RS06445
uniprot id: H8XPI4
names: Similarity
messages: Belongs to the AIR synthase family.

1094466:KQS RS05515
gene id: 1094466:KQS_RS05515
uniprot id: H8XVA9
names: Similarity
messages: Belongs to the threonine aldolase family.

1094466:KQS RS11425
gene id: 1094466:KQS_RS11425
uniprot id: H8XQ05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1094466:KQS RS07215
gene id: 1094466:KQS_RS07215
uniprot id: H8XQW5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS12680
gene id: 1094466:KQS_RS12680
uniprot id: H8XRM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1094466:KQS RS10960
gene id: 1094466:KQS_RS10960
uniprot id: H8XPR9
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS10560
gene id: 1094466:KQS_RS10560
uniprot id: H8XVU6
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1094466:KQS RS05645
gene id: 1094466:KQS_RS05645
uniprot id: H8XVD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1094466:KQS RS00205
gene id: 1094466:KQS_RS00205
uniprot id: H8XND8
names: Similarity
messages: Belongs to the SufE family.

1094466:KQS RS03810
gene id: 1094466:KQS_RS03810
uniprot id: H8XTF5
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1094466:KQS RS09745
gene id: 1094466:KQS_RS09745
uniprot id: H8XUX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1094466:KQS RS11025
gene id: 1094466:KQS_RS11025
uniprot id: H8XPT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

1094466:KQS RS09345
gene id: 1094466:KQS_RS09345
uniprot id: H8XUP5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1094466:KQS RS10985
gene id: 1094466:KQS_RS10985
uniprot id: H8XPS4
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS05205
gene id: 1094466:KQS_RS05205
uniprot id: H8XV50
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1094466:KQS RS03335
gene id: 1094466:KQS_RS03335
uniprot id: H8XT61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1094466:KQS RS03895
gene id: 1094466:KQS_RS03895
uniprot id: H8XTG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1094466:KQS RS04490
gene id: 1094466:KQS_RS04490
uniprot id: H8XU94
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1094466:KQS RS09390
gene id: 1094466:KQS_RS09390
uniprot id: H8XUQ4
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1094466:KQS RS02840
gene id: 1094466:KQS_RS02840
uniprot id: H8XSH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1094466:KQS RS01595
gene id: 1094466:KQS_RS01595
uniprot id: H8XP46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1094466:KQS RS06985
gene id: 1094466:KQS_RS06985
uniprot id: H8XQR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1094466:KQS RS12365
gene id: 1094466:KQS_RS12365
uniprot id: H8XRG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1094466:KQS RS10800
gene id: 1094466:KQS_RS10800
uniprot id: H8XPN8
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1094466:KQS RS06225
gene id: 1094466:KQS_RS06225
uniprot id: H8XPE0
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS11760
gene id: 1094466:KQS_RS11760
uniprot id: H8XR45
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1094466:KQS RS04370
gene id: 1094466:KQS_RS04370
uniprot id: H8XU76
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1094466:KQS RS02725
gene id: 1094466:KQS_RS02725
uniprot id: H8XSF4
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS10635
gene id: 1094466:KQS_RS10635
uniprot id: H8XVW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1094466:KQS RS06910
gene id: 1094466:KQS_RS06910
uniprot id: H8XQQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1094466:KQS RS09435
gene id: 1094466:KQS_RS09435
uniprot id: H8XUR2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

1094466:KQS RS06105
gene id: 1094466:KQS_RS06105
uniprot id: H8XPB9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1094466:KQS RS06930
gene id: 1094466:KQS_RS06930
uniprot id: H8XQQ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1094466:KQS RS13420
gene id: 1094466:KQS_RS13420
uniprot id: H8XS14
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

1094466:KQS RS11280
gene id: 1094466:KQS_RS11280
uniprot id: H8XPX9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1094466:KQS RS10280
gene id: 1094466:KQS_RS10280
uniprot id: H8XVP3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1094466:KQS RS00830
gene id: 1094466:KQS_RS00830
uniprot id: H8XNQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS00475
gene id: 1094466:KQS_RS00475
uniprot id: H8XNI8
names: Similarity
messages: Belongs to the peptidase M1 family.

1094466:KQS RS03805
gene id: 1094466:KQS_RS03805
uniprot id: H8XTF4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1094466:KQS RS10440
gene id: 1094466:KQS_RS10440
uniprot id: H8XVS2
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

1094466:KQS RS05120
gene id: 1094466:KQS_RS05120
uniprot id: H8XV33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1094466:KQS RS06395
gene id: 1094466:KQS_RS06395
uniprot id: H8XPH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1094466:KQS RS02615
gene id: 1094466:KQS_RS02615
uniprot id: H8XSD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1094466:KQS RS11680
gene id: 1094466:KQS_RS11680
uniprot id: H8XR29
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1094466:KQS RS04375
gene id: 1094466:KQS_RS04375
uniprot id: H8XU77
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS12415
gene id: 1094466:KQS_RS12415
uniprot id: H8XRH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1094466:KQS RS02910
gene id: 1094466:KQS_RS02910
uniprot id: H8XSJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1094466:KQS RS02865
gene id: 1094466:KQS_RS02865
uniprot id: H8XSI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1094466:KQS RS04235
gene id: 1094466:KQS_RS04235
uniprot id: H8XU49
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS06060
gene id: 1094466:KQS_RS06060
uniprot id: H8XPB1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1094466:KQS RS06280
gene id: 1094466:KQS_RS06280
uniprot id: H8XPF1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS02215
gene id: 1094466:KQS_RS02215
uniprot id: H8XQE3
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS13430
gene id: 1094466:KQS_RS13430
uniprot id: H8XS16
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1094466:KQS RS10465
gene id: 1094466:KQS_RS10465
uniprot id: H8XVS7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1094466:KQS RS13510
gene id: 1094466:KQS_RS13510
uniprot id: H8XS32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1094466:KQS RS11495
gene id: 1094466:KQS_RS11495
uniprot id: H8XQ19
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1094466:KQS RS00675
gene id: 1094466:KQS_RS00675
uniprot id: H8XNL9
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

1094466:KQS RS11665
gene id: 1094466:KQS_RS11665
uniprot id: H8XR26
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1094466:KQS RS06925
gene id: 1094466:KQS_RS06925
uniprot id: H8XQQ7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1094466:KQS RS12645
gene id: 1094466:KQS_RS12645
uniprot id: H8XRL7
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1094466:KQS RS05780
gene id: 1094466:KQS_RS05780
uniprot id: H8XP58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1094466:KQS RS07665
gene id: 1094466:KQS_RS07665
uniprot id: H8XSV4
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS04635
gene id: 1094466:KQS_RS04635
uniprot id: H8XUC0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1094466:KQS RS12795
gene id: 1094466:KQS_RS12795
uniprot id: H8XRP5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1094466:KQS RS11645
gene id: 1094466:KQS_RS11645
uniprot id: H8XR22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1094466:KQS RS07810
gene id: 1094466:KQS_RS07810
uniprot id: H8XSY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1094466:KQS RS03485
gene id: 1094466:KQS_RS03485
uniprot id: H8XT91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1094466:KQS RS05435
gene id: 1094466:KQS_RS05435
uniprot id: H8XV96
names: Similarity
messages: Belongs to the ArsC family.

1094466:KQS RS12030
gene id: 1094466:KQS_RS12030
uniprot id: H8XR98
names: Similarity
messages: Belongs to the peptidase S41A family.

1094466:KQS RS05815
gene id: 1094466:KQS_RS05815
uniprot id: H8XP63
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1094466:KQS RS03750
gene id: 1094466:KQS_RS03750
uniprot id: H8XTE3
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1094466:KQS RS03735
gene id: 1094466:KQS_RS03735
uniprot id: H8XTE0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1094466:KQS RS10740
gene id: 1094466:KQS_RS10740
uniprot id: H8XPM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1094466:KQS RS10540
gene id: 1094466:KQS_RS10540
uniprot id: H8XVU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1094466:KQS RS08600
gene id: 1094466:KQS_RS08600
uniprot id: H8XTU8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1094466:KQS RS06670
gene id: 1094466:KQS_RS06670
uniprot id: H8XQK4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1094466:KQS RS05220
gene id: 1094466:KQS_RS05220
uniprot id: H8XV53
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1094466:KQS RS10450
gene id: 1094466:KQS_RS10450
uniprot id: H8XVS4
names: Similarity
messages: Belongs to the ParB family.

1094466:KQS RS06180
gene id: 1094466:KQS_RS06180
uniprot id: H8XPD1
names: Similarity
messages: Belongs to the nitroreductase family.

1094466:KQS RS13570
gene id: 1094466:KQS_RS13570
uniprot id: H8XS44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1094466:KQS RS02430
gene id: 1094466:KQS_RS02430
uniprot id: H8XQI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1094466:KQS RS01265
gene id: 1094466:KQS_RS01265
uniprot id: H8XNY4
names: Similarity
messages: Belongs to the RecJ family.

1094466:KQS RS06475
gene id: 1094466:KQS_RS06475
uniprot id: H8XPJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1094466:KQS RS12520
gene id: 1094466:KQS_RS12520
uniprot id: H8XRJ3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1094466:KQS RS01440
gene id: 1094466:KQS_RS01440
uniprot id: H8XP16
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1094466:KQS RS06890
gene id: 1094466:KQS_RS06890
uniprot id: H8XQQ0
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1094466:KQS RS01005
gene id: 1094466:KQS_RS01005
uniprot id: H8XNT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1094466:KQS RS05520
gene id: 1094466:KQS_RS05520
uniprot id: H8XVB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

1094466:KQS RS12420
gene id: 1094466:KQS_RS12420
uniprot id: H8XRH3
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS05255
gene id: 1094466:KQS_RS05255
uniprot id: H8XV60
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1094466:KQS RS02850
gene id: 1094466:KQS_RS02850
uniprot id: H8XSI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1094466:KQS RS09540
gene id: 1094466:KQS_RS09540
uniprot id: H8XUT3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1094466:KQS RS02350
gene id: 1094466:KQS_RS02350
uniprot id: H8XQH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1094466:KQS RS09275
gene id: 1094466:KQS_RS09275
uniprot id: H8XUN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

1094466:KQS RS12880
gene id: 1094466:KQS_RS12880
uniprot id: H8XRR1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

1094466:KQS RS09370
gene id: 1094466:KQS_RS09370
uniprot id: H8XUQ0
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

1094466:KQS RS04260
gene id: 1094466:KQS_RS04260
uniprot id: H8XU54
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1094466:KQS RS04660
gene id: 1094466:KQS_RS04660
uniprot id: H8XUC5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1094466:KQS RS14160
gene id: 1094466:KQS_RS14160
uniprot id: H8XSJ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1094466:KQS RS09570
gene id: 1094466:KQS_RS09570
uniprot id: H8XUT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1094466:KQS RS02005
gene id: 1094466:KQS_RS02005
uniprot id: H8XQA1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1094466:KQS RS05775
gene id: 1094466:KQS_RS05775
uniprot id: H8XP57
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1094466:KQS RS12620
gene id: 1094466:KQS_RS12620
uniprot id: H8XRL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1094466:KQS RS03430
gene id: 1094466:KQS_RS03430
uniprot id: H8XT80
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1094466:KQS RS05245
gene id: 1094466:KQS_RS05245
uniprot id: H8XV58
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1094466:KQS RS11385
gene id: 1094466:KQS_RS11385
uniprot id: H8XPZ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1094466:KQS RS08460
gene id: 1094466:KQS_RS08460
uniprot id: H8XTS0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1094466:KQS RS01550
gene id: 1094466:KQS_RS01550
uniprot id: H8XP38
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1094466:KQS RS12140
gene id: 1094466:KQS_RS12140
uniprot id: H8XRC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1094466:KQS RS03320
gene id: 1094466:KQS_RS03320
uniprot id: H8XT58
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1094466:KQS RS11800
gene id: 1094466:KQS_RS11800
uniprot id: H8XR53
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1094466:KQS RS02805
gene id: 1094466:KQS_RS02805
uniprot id: H8XSH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1094466:KQS RS07505
gene id: 1094466:KQS_RS07505
uniprot id: H8XSS8
names: Similarity
messages: Belongs to the HsdR family.

1094466:KQS RS12475
gene id: 1094466:KQS_RS12475
uniprot id: H8XRI4
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

1094466:KQS RS06250
gene id: 1094466:KQS_RS06250
uniprot id: H8XPE5
names: Similarity
messages: Belongs to the UPF0173 family.

1094466:KQS RS04760
gene id: 1094466:KQS_RS04760
uniprot id: H8XUE5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1094466:KQS RS12445
gene id: 1094466:KQS_RS12445
uniprot id: H8XRH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS03140
gene id: 1094466:KQS_RS03140
uniprot id: H8XSN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1094466:KQS RS11015
gene id: 1094466:KQS_RS11015
uniprot id: H8XPT0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1094466:KQS RS10745
gene id: 1094466:KQS_RS10745
uniprot id: H8XPM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1094466:KQS RS07185
gene id: 1094466:KQS_RS07185
uniprot id: H8XQV9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1094466:KQS RS13670
gene id: 1094466:KQS_RS13670
uniprot id: H8XS64
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1094466:KQS RS04445
gene id: 1094466:KQS_RS04445
uniprot id: H8XU90
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1094466:KQS RS04390
gene id: 1094466:KQS_RS04390
uniprot id: H8XU80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1094466:KQS RS13640
gene id: 1094466:KQS_RS13640
uniprot id: H8XS58
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1094466:KQS RS09915
gene id: 1094466:KQS_RS09915
uniprot id: H8XVG9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1094466:KQS RS04555
gene id: 1094466:KQS_RS04555
uniprot id: H8XUA7
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1094466:KQS RS02860
gene id: 1094466:KQS_RS02860
uniprot id: H8XSI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1094466:KQS RS10630
gene id: 1094466:KQS_RS10630
uniprot id: H8XVW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1094466:KQS RS10480
gene id: 1094466:KQS_RS10480
uniprot id: H8XVT0
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS00055
gene id: 1094466:KQS_RS00055
uniprot id: H8XNA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1094466:KQS RS11745
gene id: 1094466:KQS_RS11745
uniprot id: H8XR42
names: Subcellular Location Annotation
messages: Membrane

1094466:KQS RS04340
gene id: 1094466:KQS_RS04340
uniprot id: H8XU70
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

1094466:KQS RS11165
gene id: 1094466:KQS_RS11165
uniprot id: H8XPV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1094466:KQS RS12345
gene id: 1094466:KQS_RS12345
uniprot id: H8XRF8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1094466:KQS RS04025
gene id: 1094466:KQS_RS04025
uniprot id: H8XTJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1094466:KQS RS01775
gene id: 1094466:KQS_RS01775
uniprot id: H8XQ55
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.