1086726:ACH24 RS05555
gene id: 1086726:ACH24_RS05555
uniprot id: A0A0K2JS96
names: Similarity
messages: Belongs to the glutamine synthetase family.

1086726:ACH24 RS00565
gene id: 1086726:ACH24_RS00565
uniprot id: A0A0K2JR16
names: Similarity
messages: Belongs to the Skp family.

1086726:ACH24 RS00425
gene id: 1086726:ACH24_RS00425
uniprot id: A0A0K2JQB1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1086726:ACH24 RS06630
gene id: 1086726:ACH24_RS06630
uniprot id: A0A0K2JT15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1086726:ACH24 RS00195
gene id: 1086726:ACH24_RS00195
uniprot id: A0A0K2JT20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1086726:ACH24 RS00235
gene id: 1086726:ACH24_RS00235
uniprot id: A0A0K2JPY3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS05000
gene id: 1086726:ACH24_RS05000
uniprot id: A0A0K2JS12
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS05565
gene id: 1086726:ACH24_RS05565
uniprot id: A0A0K2JT78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

1086726:ACH24 RS02510
gene id: 1086726:ACH24_RS02510
uniprot id: A0A0K2JQX2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS05655
gene id: 1086726:ACH24_RS05655
uniprot id: A0A0K2JSP0
names: Similarity
messages: Belongs to the YggT family.

1086726:ACH24 RS04275
gene id: 1086726:ACH24_RS04275
uniprot id: A0A0K2JSU9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1086726:ACH24 RS06380
gene id: 1086726:ACH24_RS06380
uniprot id: A0A0K2JSY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1086726:ACH24 RS04630
gene id: 1086726:ACH24_RS04630
uniprot id: A0A0K2JSV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1086726:ACH24 RS02330
gene id: 1086726:ACH24_RS02330
uniprot id: A0A0K2JQV0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1086726:ACH24 RS03105
gene id: 1086726:ACH24_RS03105
uniprot id: A0A0K2JRI0
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS01365
gene id: 1086726:ACH24_RS01365
uniprot id: A0A0K2JQG5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1086726:ACH24 RS02970
gene id: 1086726:ACH24_RS02970
uniprot id: A0A0K2JR54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1086726:ACH24 RS02190
gene id: 1086726:ACH24_RS02190
uniprot id: A0A0K2JQS7
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS01380
gene id: 1086726:ACH24_RS01380
uniprot id: A0A0K2JQU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1086726:ACH24 RS05170
gene id: 1086726:ACH24_RS05170
uniprot id: A0A0K2JSG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1086726:ACH24 RS04105
gene id: 1086726:ACH24_RS04105
uniprot id: A0A0K2JSK8
names: Similarity
messages: Belongs to the BolA/IbaG family.

1086726:ACH24 RS04635
gene id: 1086726:ACH24_RS04635
uniprot id: A0A0K2JS87
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS05930
gene id: 1086726:ACH24_RS05930
uniprot id: A0A0K2JSR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1086726:ACH24 RS06340
gene id: 1086726:ACH24_RS06340
uniprot id: A0A0K2JSL4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1086726:ACH24 RS00695
gene id: 1086726:ACH24_RS00695
uniprot id: A0A0K2JR39
names: Similarity
messages: Belongs to the NAPRTase family.

1086726:ACH24 RS03500
gene id: 1086726:ACH24_RS03500
uniprot id: A0A0K2JRC7
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1086726:ACH24 RS06290
gene id: 1086726:ACH24_RS06290
uniprot id: A0A0K2JSL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1086726:ACH24 RS00355
gene id: 1086726:ACH24_RS00355
uniprot id: A0A0K2JQ03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1086726:ACH24 RS02490
gene id: 1086726:ACH24_RS02490
uniprot id: A0A0K2JQX4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1086726:ACH24 RS06055
gene id: 1086726:ACH24_RS06055
uniprot id: A0A0K2JTF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1086726:ACH24 RS00360
gene id: 1086726:ACH24_RS00360
uniprot id: A0A0K2JQY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1086726:ACH24 RS05150
gene id: 1086726:ACH24_RS05150
uniprot id: A0A0K2JSE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1086726:ACH24 RS04875
gene id: 1086726:ACH24_RS04875
uniprot id: A0A0K2JRZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1086726:ACH24 RS00015
gene id: 1086726:ACH24_RS00015
uniprot id: A0A0K2JQ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1086726:ACH24 RS04445
gene id: 1086726:ACH24_RS04445
uniprot id: A0A0K2JRS8
names: Similarity
messages: Belongs to the bacterial glucokinase family.

1086726:ACH24 RS01735
gene id: 1086726:ACH24_RS01735
uniprot id: A0A0K2JQX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1086726:ACH24 RS05195
gene id: 1086726:ACH24_RS05195
uniprot id: A0A0K2JSH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1086726:ACH24 RS02620
gene id: 1086726:ACH24_RS02620
uniprot id: A0A0K2JRC3
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS06435
gene id: 1086726:ACH24_RS06435
uniprot id: A0A0K2JSX7
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS05290
gene id: 1086726:ACH24_RS05290
uniprot id: A0A0K2JS55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1086726:ACH24 RS01555
gene id: 1086726:ACH24_RS01555
uniprot id: A0A0K2JQU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1086726:ACH24 RS02525
gene id: 1086726:ACH24_RS02525
uniprot id: A0A0K2JRW6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1086726:ACH24 RS06450
gene id: 1086726:ACH24_RS06450
uniprot id: A0A0K2JSW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1086726:ACH24 RS00140
gene id: 1086726:ACH24_RS00140
uniprot id: A0A0K2JQU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1086726:ACH24 RS00310
gene id: 1086726:ACH24_RS00310
uniprot id: A0A0K2JQ04
names: Similarity
messages: Belongs to the YfgM family.

1086726:ACH24 RS02280
gene id: 1086726:ACH24_RS02280
uniprot id: A0A0K2JQU5
names: Similarity
messages: Belongs to the UPF0434 family.

1086726:ACH24 RS02385
gene id: 1086726:ACH24_RS02385
uniprot id: A0A0K2JRT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1086726:ACH24 RS02245
gene id: 1086726:ACH24_RS02245
uniprot id: A0A0K2JQU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1086726:ACH24 RS04780
gene id: 1086726:ACH24_RS04780
uniprot id: A0A0K2JRY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1086726:ACH24 RS05985
gene id: 1086726:ACH24_RS05985
uniprot id: A0A0K2JSS5
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1086726:ACH24 RS04945
gene id: 1086726:ACH24_RS04945
uniprot id: A0A0K2JSB4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1086726:ACH24 RS02595
gene id: 1086726:ACH24_RS02595
uniprot id: A0A0K2JRB8
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1086726:ACH24 RS00205
gene id: 1086726:ACH24_RS00205
uniprot id: A0A0K2JPY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1086726:ACH24 RS05420
gene id: 1086726:ACH24_RS05420
uniprot id: A0A0K2JT60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1086726:ACH24 RS01220
gene id: 1086726:ACH24_RS01220
uniprot id: A0A0K2JQE8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1086726:ACH24 RS00305
gene id: 1086726:ACH24_RS00305
uniprot id: A0A0K2JQA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1086726:ACH24 RS01650
gene id: 1086726:ACH24_RS01650
uniprot id: A0A0K2JQW3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1086726:ACH24 RS06200
gene id: 1086726:ACH24_RS06200
uniprot id: A0A0K2JTH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1086726:ACH24 RS03780
gene id: 1086726:ACH24_RS03780
uniprot id: A0A0K2JRS5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1086726:ACH24 RS02410
gene id: 1086726:ACH24_RS02410
uniprot id: A0A0K2JRU4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1086726:ACH24 RS00110
gene id: 1086726:ACH24_RS00110
uniprot id: A0A0K2JQ87
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1086726:ACH24 RS03335
gene id: 1086726:ACH24_RS03335
uniprot id: A0A0K2JRA2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1086726:ACH24 RS00210
gene id: 1086726:ACH24_RS00210
uniprot id: A0A0K2JPX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1086726:ACH24 RS02555
gene id: 1086726:ACH24_RS02555
uniprot id: A0A0K2JRX0
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1086726:ACH24 RS03620
gene id: 1086726:ACH24_RS03620
uniprot id: A0A0K2JSE0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1086726:ACH24 RS06025
gene id: 1086726:ACH24_RS06025
uniprot id: A0A0K2JSU8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1086726:ACH24 RS02710
gene id: 1086726:ACH24_RS02710
uniprot id: A0A0K2JRD9
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1086726:ACH24 RS03030
gene id: 1086726:ACH24_RS03030
uniprot id: A0A0K2JS42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1086726:ACH24 RS01835
gene id: 1086726:ACH24_RS01835
uniprot id: A0A0K2JQM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1086726:ACH24 RS00410
gene id: 1086726:ACH24_RS00410
uniprot id: A0A0K2JQY8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1086726:ACH24 RS00820
gene id: 1086726:ACH24_RS00820
uniprot id: A0A0K2JQ83
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1086726:ACH24 RS03900
gene id: 1086726:ACH24_RS03900
uniprot id: A0A0K2JSI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1086726:ACH24 RS03745
gene id: 1086726:ACH24_RS03745
uniprot id: A0A0K2JRG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1086726:ACH24 RS02115
gene id: 1086726:ACH24_RS02115
uniprot id: A0A0K2JRQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1086726:ACH24 RS06030
gene id: 1086726:ACH24_RS06030
uniprot id: A0A0K2JST0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS04845
gene id: 1086726:ACH24_RS04845
uniprot id: A0A0K2JRY8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1086726:ACH24 RS02075
gene id: 1086726:ACH24_RS02075
uniprot id: A0A0K2JR49
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS03430
gene id: 1086726:ACH24_RS03430
uniprot id: A0A0K2JRC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1086726:ACH24 RS04760
gene id: 1086726:ACH24_RS04760
uniprot id: A0A0K2JSX0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1086726:ACH24 RS02775
gene id: 1086726:ACH24_RS02775
uniprot id: A0A0K2JR25
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS00765
gene id: 1086726:ACH24_RS00765
uniprot id: A0A0K2JQ75
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS06550
gene id: 1086726:ACH24_RS06550
uniprot id: A0A0K2JSZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1086726:ACH24 RS02870
gene id: 1086726:ACH24_RS02870
uniprot id: A0A0K2JR32
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1086726:ACH24 RS02795
gene id: 1086726:ACH24_RS02795
uniprot id: A0A0K2JRF3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1086726:ACH24 RS04510
gene id: 1086726:ACH24_RS04510
uniprot id: A0A0K2JRU2
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1086726:ACH24 RS04070
gene id: 1086726:ACH24_RS04070
uniprot id: A0A0K2JRZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1086726:ACH24 RS06395
gene id: 1086726:ACH24_RS06395
uniprot id: A0A0K2JSM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1086726:ACH24 RS03795
gene id: 1086726:ACH24_RS03795
uniprot id: A0A0K2JSG6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1086726:ACH24 RS01915
gene id: 1086726:ACH24_RS01915
uniprot id: A0A0K2JR01
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1086726:ACH24 RS01820
gene id: 1086726:ACH24_RS01820
uniprot id: A0A0K2JRL8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1086726:ACH24 RS02275
gene id: 1086726:ACH24_RS02275
uniprot id: A0A0K2JQT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1086726:ACH24 RS05770
gene id: 1086726:ACH24_RS05770
uniprot id: A0A0K2JSD2
names: Similarity
messages: Belongs to the peptidase S49 family.

1086726:ACH24 RS05755
gene id: 1086726:ACH24_RS05755
uniprot id: A0A0K2JSQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1086726:ACH24 RS05165
gene id: 1086726:ACH24_RS05165
uniprot id: A0A0K2JT27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1086726:ACH24 RS03520
gene id: 1086726:ACH24_RS03520
uniprot id: A0A0K2JRP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1086726:ACH24 RS00570
gene id: 1086726:ACH24_RS00570
uniprot id: A0A0K2JQF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1086726:ACH24 RS02080
gene id: 1086726:ACH24_RS02080
uniprot id: A0A0K2JR29
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1086726:ACH24 RS06620
gene id: 1086726:ACH24_RS06620
uniprot id: A0A0K2JTP0
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1086726:ACH24 RS05105
gene id: 1086726:ACH24_RS05105
uniprot id: A0A0K2JS25
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS06335
gene id: 1086726:ACH24_RS06335
uniprot id: A0A0K2JSW4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1086726:ACH24 RS06325
gene id: 1086726:ACH24_RS06325
uniprot id: A0A0K2JTI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1086726:ACH24 RS00090
gene id: 1086726:ACH24_RS00090
uniprot id: A0A0K2JPW9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1086726:ACH24 RS02730
gene id: 1086726:ACH24_RS02730
uniprot id: A0A0K2JS00
names: Similarity
messages: Belongs to the asparaginase 1 family.

1086726:ACH24 RS00750
gene id: 1086726:ACH24_RS00750
uniprot id: A0A0K2JQI8
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1086726:ACH24 RS05735
gene id: 1086726:ACH24_RS05735
uniprot id: A0A0K2JSN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1086726:ACH24 RS00300
gene id: 1086726:ACH24_RS00300
uniprot id: A0A0K2JQB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1086726:ACH24 RS01795
gene id: 1086726:ACH24_RS01795
uniprot id: A0A0K2JR02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1086726:ACH24 RS03575
gene id: 1086726:ACH24_RS03575
uniprot id: A0A0K2JRR7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1086726:ACH24 RS01740
gene id: 1086726:ACH24_RS01740
uniprot id: A0A0K2JQL1
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS01935
gene id: 1086726:ACH24_RS01935
uniprot id: A0A0K2JR26
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS02850
gene id: 1086726:ACH24_RS02850
uniprot id: A0A0K2JR35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1086726:ACH24 RS06430
gene id: 1086726:ACH24_RS06430
uniprot id: A0A0K2JT00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1086726:ACH24 RS06475
gene id: 1086726:ACH24_RS06475
uniprot id: A0A0K2JSY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1086726:ACH24 RS05740
gene id: 1086726:ACH24_RS05740
uniprot id: A0A0K2JSC7
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1086726:ACH24 RS01495
gene id: 1086726:ACH24_RS01495
uniprot id: A0A0K2JQT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1086726:ACH24 RS05075
gene id: 1086726:ACH24_RS05075
uniprot id: A0A0K2JS17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1086726:ACH24 RS03180
gene id: 1086726:ACH24_RS03180
uniprot id: A0A0K2JS65
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1086726:ACH24 RS04880
gene id: 1086726:ACH24_RS04880
uniprot id: A0A0K2JRZ5
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

1086726:ACH24 RS00785
gene id: 1086726:ACH24_RS00785
uniprot id: A0A0K2JQH4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1086726:ACH24 RS00640
gene id: 1086726:ACH24_RS00640
uniprot id: A0A0K2JQ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1086726:ACH24 RS06240
gene id: 1086726:ACH24_RS06240
uniprot id: A0A0K2JSK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

1086726:ACH24 RS01180
gene id: 1086726:ACH24_RS01180
uniprot id: A0A0K2JQR4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1086726:ACH24 RS05845
gene id: 1086726:ACH24_RS05845
uniprot id: A0A0K2JTC6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1086726:ACH24 RS01875
gene id: 1086726:ACH24_RS01875
uniprot id: A0A0K2JR17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1086726:ACH24 RS03205
gene id: 1086726:ACH24_RS03205
uniprot id: A0A0K2JR90
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

1086726:ACH24 RS04905
gene id: 1086726:ACH24_RS04905
uniprot id: A0A0K2JRZ9
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1086726:ACH24 RS01100
gene id: 1086726:ACH24_RS01100
uniprot id: A0A0K2JQQ4
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1086726:ACH24 RS03930
gene id: 1086726:ACH24_RS03930
uniprot id: A0A0K2JRX6
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS03150
gene id: 1086726:ACH24_RS03150
uniprot id: A0A0K2JS61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1086726:ACH24 RS03020
gene id: 1086726:ACH24_RS03020
uniprot id: A0A0K2JR64
names: Similarity
messages: Belongs to the peptidase M16 family.

1086726:ACH24 RS04120
gene id: 1086726:ACH24_RS04120
uniprot id: A0A0K2JRM0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1086726:ACH24 RS06015
gene id: 1086726:ACH24_RS06015
uniprot id: A0A0K2JTF3
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1086726:ACH24 RS04320
gene id: 1086726:ACH24_RS04320
uniprot id: A0A0K2JS23
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

1086726:ACH24 RS01235
gene id: 1086726:ACH24_RS01235
uniprot id: A0A0K2JQQ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1086726:ACH24 RS06440
gene id: 1086726:ACH24_RS06440
uniprot id: A0A0K2JSM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1086726:ACH24 RS01855
gene id: 1086726:ACH24_RS01855
uniprot id: A0A0K2JQZ1
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS04595
gene id: 1086726:ACH24_RS04595
uniprot id: A0A0K2JSU7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1086726:ACH24 RS04610
gene id: 1086726:ACH24_RS04610
uniprot id: A0A0K2JS82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1086726:ACH24 RS00190
gene id: 1086726:ACH24_RS00190
uniprot id: A0A0K2JQ97
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1086726:ACH24 RS05615
gene id: 1086726:ACH24_RS05615
uniprot id: A0A0K2JSB1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1086726:ACH24 RS05130
gene id: 1086726:ACH24_RS05130
uniprot id: A0A0K2JS26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1086726:ACH24 RS01355
gene id: 1086726:ACH24_RS01355
uniprot id: A0A0K2JQU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1086726:ACH24 RS06625
gene id: 1086726:ACH24_RS06625
uniprot id: A0A0K2JT36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1086726:ACH24 RS06640
gene id: 1086726:ACH24_RS06640
uniprot id: A0A0K2JSQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1086726:ACH24 RS06510
gene id: 1086726:ACH24_RS06510
uniprot id: A0A0K2JSP3
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS06425
gene id: 1086726:ACH24_RS06425
uniprot id: A0A0K2JTK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1086726:ACH24 RS03610
gene id: 1086726:ACH24_RS03610
uniprot id: A0A0K2JRE7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1086726:ACH24 RS02635
gene id: 1086726:ACH24_RS02635
uniprot id: A0A0K2JQZ2
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1086726:ACH24 RS05535
gene id: 1086726:ACH24_RS05535
uniprot id: A0A0K2JT73
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1086726:ACH24 RS05245
gene id: 1086726:ACH24_RS05245
uniprot id: A0A0K2JT40
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1086726:ACH24 RS00445
gene id: 1086726:ACH24_RS00445
uniprot id: A0A0K2JQZ4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1086726:ACH24 RS04480
gene id: 1086726:ACH24_RS04480
uniprot id: A0A0K2JRT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1086726:ACH24 RS04020
gene id: 1086726:ACH24_RS04020
uniprot id: A0A0K2JRV8
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1086726:ACH24 RS00185
gene id: 1086726:ACH24_RS00185
uniprot id: A0A0K2JQU8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1086726:ACH24 RS05065
gene id: 1086726:ACH24_RS05065
uniprot id: A0A0K2JSE6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1086726:ACH24 RS04140
gene id: 1086726:ACH24_RS04140
uniprot id: A0A0K2JRY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1086726:ACH24 RS00230
gene id: 1086726:ACH24_RS00230
uniprot id: A0A0K2JPY9
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS02530
gene id: 1086726:ACH24_RS02530
uniprot id: A0A0K2JRA9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1086726:ACH24 RS01120
gene id: 1086726:ACH24_RS01120
uniprot id: A0A0K2JQD3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS01400
gene id: 1086726:ACH24_RS01400
uniprot id: A0A0K2JQH5
names: Subcellular Location Annotation
messages: Cytoplasm

1086726:ACH24 RS05610
gene id: 1086726:ACH24_RS05610
uniprot id: A0A0K2JSA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1086726:ACH24 RS00055
gene id: 1086726:ACH24_RS00055
uniprot id: A0A0K2JPW3
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS01625
gene id: 1086726:ACH24_RS01625
uniprot id: A0A0K2JQV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1086726:ACH24 RS05275
gene id: 1086726:ACH24_RS05275
uniprot id: A0A0K2JT44
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1086726:ACH24 RS00200
gene id: 1086726:ACH24_RS00200
uniprot id: A0A0K2JQ84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1086726:ACH24 RS05225
gene id: 1086726:ACH24_RS05225
uniprot id: A0A0K2JSH4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1086726:ACH24 RS04115
gene id: 1086726:ACH24_RS04115
uniprot id: A0A0K2JRX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1086726:ACH24 RS03015
gene id: 1086726:ACH24_RS03015
uniprot id: A0A0K2JR59
names: Similarity
messages: Belongs to the peptidase M16 family.

1086726:ACH24 RS06615
gene id: 1086726:ACH24_RS06615
uniprot id: A0A0K2JSR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1086726:ACH24 RS00450
gene id: 1086726:ACH24_RS00450
uniprot id: A0A0K2JQD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1086726:ACH24 RS02655
gene id: 1086726:ACH24_RS02655
uniprot id: A0A0K2JRA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

1086726:ACH24 RS03140
gene id: 1086726:ACH24_RS03140
uniprot id: A0A0K2JR80
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1086726:ACH24 RS06330
gene id: 1086726:ACH24_RS06330
uniprot id: A0A0K2JSY1
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1086726:ACH24 RS05650
gene id: 1086726:ACH24_RS05650
uniprot id: A0A0K2JT95
names: Similarity
messages: Belongs to the UPF0235 family.

1086726:ACH24 RS03725
gene id: 1086726:ACH24_RS03725
uniprot id: A0A0K2JST4
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1086726:ACH24 RS03595
gene id: 1086726:ACH24_RS03595
uniprot id: A0A0K2JSD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1086726:ACH24 RS03865
gene id: 1086726:ACH24_RS03865
uniprot id: A0A0K2JRW7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1086726:ACH24 RS03585
gene id: 1086726:ACH24_RS03585
uniprot id: A0A0K2JRE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1086726:ACH24 RS04985
gene id: 1086726:ACH24_RS04985
uniprot id: A0A0K2JSD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

1086726:ACH24 RS01535
gene id: 1086726:ACH24_RS01535
uniprot id: A0A0K2JQJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1086726:ACH24 RS05855
gene id: 1086726:ACH24_RS05855
uniprot id: A0A0K2JSP9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1086726:ACH24 RS06565
gene id: 1086726:ACH24_RS06565
uniprot id: A0A0K2JTN0
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1086726:ACH24 RS02650
gene id: 1086726:ACH24_RS02650
uniprot id: A0A0K2JRC8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1086726:ACH24 RS01160
gene id: 1086726:ACH24_RS01160
uniprot id: A0A0K2JTQ7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1086726:ACH24 RS04720
gene id: 1086726:ACH24_RS04720
uniprot id: A0A0K2JS79
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1086726:ACH24 RS01050
gene id: 1086726:ACH24_RS01050
uniprot id: A0A0K2JSS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1086726:ACH24 RS03310
gene id: 1086726:ACH24_RS03310
uniprot id: A0A0K2JR99
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1086726:ACH24 RS01415
gene id: 1086726:ACH24_RS01415
uniprot id: A0A0K2JQS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1086726:ACH24 RS03135
gene id: 1086726:ACH24_RS03135
uniprot id: A0A0K2JRI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1086726:ACH24 RS01455
gene id: 1086726:ACH24_RS01455
uniprot id: A0A0K2JQH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1086726:ACH24 RS02690
gene id: 1086726:ACH24_RS02690
uniprot id: A0A0K2JR04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1086726:ACH24 RS05465
gene id: 1086726:ACH24_RS05465
uniprot id: A0A0K2JS86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1086726:ACH24 RS01215
gene id: 1086726:ACH24_RS01215
uniprot id: A0A0K2JQE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1086726:ACH24 RS05965
gene id: 1086726:ACH24_RS05965
uniprot id: A0A0K2JSG9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1086726:ACH24 RS03440
gene id: 1086726:ACH24_RS03440
uniprot id: A0A0K2JRQ0
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS06400
gene id: 1086726:ACH24_RS06400
uniprot id: A0A0K2JTJ6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1086726:ACH24 RS03580
gene id: 1086726:ACH24_RS03580
uniprot id: A0A0K2JRP8
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1086726:ACH24 RS03065
gene id: 1086726:ACH24_RS03065
uniprot id: A0A0K2JS47
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS03260
gene id: 1086726:ACH24_RS03260
uniprot id: A0A0K2JT55
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1086726:ACH24 RS05780
gene id: 1086726:ACH24_RS05780
uniprot id: A0A0K2JSD6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1086726:ACH24 RS06405
gene id: 1086726:ACH24_RS06405
uniprot id: A0A0K2JSZ5
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1086726:ACH24 RS02565
gene id: 1086726:ACH24_RS02565
uniprot id: A0A0K2JR92
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1086726:ACH24 RS01890
gene id: 1086726:ACH24_RS01890
uniprot id: A0A0K2JQN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1086726:ACH24 RS05450
gene id: 1086726:ACH24_RS05450
uniprot id: A0A0K2JSJ1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1086726:ACH24 RS02335
gene id: 1086726:ACH24_RS02335
uniprot id: A0A0K2JRT4
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS04825
gene id: 1086726:ACH24_RS04825
uniprot id: A0A0K2JSY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1086726:ACH24 RS00125
gene id: 1086726:ACH24_RS00125
uniprot id: A0A0K2JQ74
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS03560
gene id: 1086726:ACH24_RS03560
uniprot id: A0A0K2JRE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1086726:ACH24 RS02865
gene id: 1086726:ACH24_RS02865
uniprot id: A0A0K2JRE0
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1086726:ACH24 RS05765
gene id: 1086726:ACH24_RS05765
uniprot id: A0A0K2JSN8
names: Similarity
messages: Belongs to the Skp family.

1086726:ACH24 RS05750
gene id: 1086726:ACH24_RS05750
uniprot id: A0A0K2JTB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1086726:ACH24 RS04145
gene id: 1086726:ACH24_RS04145
uniprot id: A0A0K2JRM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1086726:ACH24 RS01375
gene id: 1086726:ACH24_RS01375
uniprot id: A0A0K2JRF8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1086726:ACH24 RS01405
gene id: 1086726:ACH24_RS01405
uniprot id: A0A0K2JRG3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1086726:ACH24 RS04380
gene id: 1086726:ACH24_RS04380
uniprot id: A0A0K2JSR7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS00775
gene id: 1086726:ACH24_RS00775
uniprot id: A0A0K2JR57
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1086726:ACH24 RS02015
gene id: 1086726:ACH24_RS02015
uniprot id: A0A0K2JR41
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS00480
gene id: 1086726:ACH24_RS00480
uniprot id: A0A0K2JQC1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1086726:ACH24 RS02470
gene id: 1086726:ACH24_RS02470
uniprot id: A0A0K2JRV4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1086726:ACH24 RS03705
gene id: 1086726:ACH24_RS03705
uniprot id: A0A0K2JRH1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1086726:ACH24 RS03130
gene id: 1086726:ACH24_RS03130
uniprot id: A0A0K2JRK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1086726:ACH24 RS04100
gene id: 1086726:ACH24_RS04100
uniprot id: A0A0K2JRM1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1086726:ACH24 RS04280
gene id: 1086726:ACH24_RS04280
uniprot id: A0A0K2JS20
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1086726:ACH24 RS01850
gene id: 1086726:ACH24_RS01850
uniprot id: A0A0K2JR12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1086726:ACH24 RS04935
gene id: 1086726:ACH24_RS04935
uniprot id: A0A0K2JSZ6
names: Similarity
messages: Belongs to the BolA/IbaG family.

1086726:ACH24 RS04040
gene id: 1086726:ACH24_RS04040
uniprot id: A0A0K2JSJ8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1086726:ACH24 RS03190
gene id: 1086726:ACH24_RS03190
uniprot id: A0A0K2JRJ8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1086726:ACH24 RS02225
gene id: 1086726:ACH24_RS02225
uniprot id: A0A0K2JR68
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1086726:ACH24 RS04565
gene id: 1086726:ACH24_RS04565
uniprot id: A0A0K2JSU3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1086726:ACH24 RS02725
gene id: 1086726:ACH24_RS02725
uniprot id: A0A0K2JR15
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1086726:ACH24 RS03055
gene id: 1086726:ACH24_RS03055
uniprot id: A0A0K2JR65
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS05470
gene id: 1086726:ACH24_RS05470
uniprot id: A0A0K2JT63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1086726:ACH24 RS02425
gene id: 1086726:ACH24_RS02425
uniprot id: A0A0K2JSU0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1086726:ACH24 RS04520
gene id: 1086726:ACH24_RS04520
uniprot id: A0A0K2JS68
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1086726:ACH24 RS00625
gene id: 1086726:ACH24_RS00625
uniprot id: A0A0K2JR27
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1086726:ACH24 RS03700
gene id: 1086726:ACH24_RS03700
uniprot id: A0A0K2JRG2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1086726:ACH24 RS00760
gene id: 1086726:ACH24_RS00760
uniprot id: A0A0K2JT45
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1086726:ACH24 RS03515
gene id: 1086726:ACH24_RS03515
uniprot id: A0A0K2JRQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1086726:ACH24 RS03275
gene id: 1086726:ACH24_RS03275
uniprot id: A0A0K2JRM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS05010
gene id: 1086726:ACH24_RS05010
uniprot id: A0A0K2JT06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1086726:ACH24 RS02835
gene id: 1086726:ACH24_RS02835
uniprot id: A0A0K2JRF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1086726:ACH24 RS04665
gene id: 1086726:ACH24_RS04665
uniprot id: A0A0K2JSV6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1086726:ACH24 RS01225
gene id: 1086726:ACH24_RS01225
uniprot id: A0A0K2JRD7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1086726:ACH24 RS00520
gene id: 1086726:ACH24_RS00520
uniprot id: A0A0K2JQE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1086726:ACH24 RS03695
gene id: 1086726:ACH24_RS03695
uniprot id: A0A0K2JRR3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1086726:ACH24 RS03895
gene id: 1086726:ACH24_RS03895
uniprot id: A0A0K2JRJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1086726:ACH24 RS04705
gene id: 1086726:ACH24_RS04705
uniprot id: A0A0K2JSW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1086726:ACH24 RS01095
gene id: 1086726:ACH24_RS01095
uniprot id: A0A0K2JRC0
names: Similarity
messages: Belongs to the glutamate synthase family.

1086726:ACH24 RS02695
gene id: 1086726:ACH24_RS02695
uniprot id: A0A0K2JR09
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1086726:ACH24 RS05745
gene id: 1086726:ACH24_RS05745
uniprot id: A0A0K2JSD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1086726:ACH24 RS02480
gene id: 1086726:ACH24_RS02480
uniprot id: A0A0K2JR81
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1086726:ACH24 RS03110
gene id: 1086726:ACH24_RS03110
uniprot id: A0A0K2JR75
names: Similarity
messages: Belongs to the peptidase S13 family.

1086726:ACH24 RS05240
gene id: 1086726:ACH24_RS05240
uniprot id: A0A0K2JS50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1086726:ACH24 RS05190
gene id: 1086726:ACH24_RS05190
uniprot id: A0A0K2JT32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1086726:ACH24 RS00150
gene id: 1086726:ACH24_RS00150
uniprot id: A0A0K2JQ78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1086726:ACH24 RS05265
gene id: 1086726:ACH24_RS05265
uniprot id: A0A0K2JS51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1086726:ACH24 RS06040
gene id: 1086726:ACH24_RS06040
uniprot id: A0A0K2JSI3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1086726:ACH24 RS03590
gene id: 1086726:ACH24_RS03590
uniprot id: A0A0K2JRF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1086726:ACH24 RS04085
gene id: 1086726:ACH24_RS04085
uniprot id: A0A0K2JRL3
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1086726:ACH24 RS01030
gene id: 1086726:ACH24_RS01030
uniprot id: A0A0K2JQM7
names: Similarity
messages: Belongs to the SufE family.

1086726:ACH24 RS05095
gene id: 1086726:ACH24_RS05095
uniprot id: A0A0K2JSD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1086726:ACH24 RS05990
gene id: 1086726:ACH24_RS05990
uniprot id: A0A0K2JSV7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1086726:ACH24 RS00535
gene id: 1086726:ACH24_RS00535
uniprot id: A0A0K2JQ29
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1086726:ACH24 RS00295
gene id: 1086726:ACH24_RS00295
uniprot id: A0A0K2JSR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1086726:ACH24 RS05070
gene id: 1086726:ACH24_RS05070
uniprot id: A0A0K2JSC9
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1086726:ACH24 RS01870
gene id: 1086726:ACH24_RS01870
uniprot id: A0A0K2JRM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1086726:ACH24 RS01580
gene id: 1086726:ACH24_RS01580
uniprot id: A0A0K2JQJ4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1086726:ACH24 RS05595
gene id: 1086726:ACH24_RS05595
uniprot id: A0A0K2JT83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1086726:ACH24 RS05250
gene id: 1086726:ACH24_RS05250
uniprot id: A0A0K2JT53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1086726:ACH24 RS04130
gene id: 1086726:ACH24_RS04130
uniprot id: A0A0K2JSL3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1086726:ACH24 RS01385
gene id: 1086726:ACH24_RS01385
uniprot id: A0A0K2JQS4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1086726:ACH24 RS05790
gene id: 1086726:ACH24_RS05790
uniprot id: A0A0K2JT74
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1086726:ACH24 RS02035
gene id: 1086726:ACH24_RS02035
uniprot id: A0A0K2JQR1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1086726:ACH24 RS02305
gene id: 1086726:ACH24_RS02305
uniprot id: A0A0K2JR79
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1086726:ACH24 RS05410
gene id: 1086726:ACH24_RS05410
uniprot id: A0A0K2JS81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1086726:ACH24 RS05980
gene id: 1086726:ACH24_RS05980
uniprot id: A0A0K2JSU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1086726:ACH24 RS03120
gene id: 1086726:ACH24_RS03120
uniprot id: A0A0K2JR78
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS05945
gene id: 1086726:ACH24_RS05945
uniprot id: A0A0K2JSG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1086726:ACH24 RS04335
gene id: 1086726:ACH24_RS04335
uniprot id: A0A0K2JSR4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1086726:ACH24 RS02985
gene id: 1086726:ACH24_RS02985
uniprot id: A0A0K2JRG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1086726:ACH24 RS06505
gene id: 1086726:ACH24_RS06505
uniprot id: A0A0K2JSN7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1086726:ACH24 RS02000
gene id: 1086726:ACH24_RS02000
uniprot id: A0A0K2JQP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1086726:ACH24 RS05795
gene id: 1086726:ACH24_RS05795
uniprot id: A0A0K2JSQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1086726:ACH24 RS02505
gene id: 1086726:ACH24_RS02505
uniprot id: A0A0K2JR86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1086726:ACH24 RS02930
gene id: 1086726:ACH24_RS02930
uniprot id: A0A0K2JR43
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1086726:ACH24 RS02485
gene id: 1086726:ACH24_RS02485
uniprot id: A0A0K2JQW7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1086726:ACH24 RS02935
gene id: 1086726:ACH24_RS02935
uniprot id: A0A0K2JR50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1086726:ACH24 RS03085
gene id: 1086726:ACH24_RS03085
uniprot id: A0A0K2JR74
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS06390
gene id: 1086726:ACH24_RS06390
uniprot id: A0A0K2JSL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1086726:ACH24 RS04200
gene id: 1086726:ACH24_RS04200
uniprot id: A0A0K2JS10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS06420
gene id: 1086726:ACH24_RS06420
uniprot id: A0A0K2JSN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1086726:ACH24 RS04895
gene id: 1086726:ACH24_RS04895
uniprot id: A0A0K2JSA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1086726:ACH24 RS03670
gene id: 1086726:ACH24_RS03670
uniprot id: A0A0K2JRG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1086726:ACH24 RS03765
gene id: 1086726:ACH24_RS03765
uniprot id: A0A0K2JRH8
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1086726:ACH24 RS01830
gene id: 1086726:ACH24_RS01830
uniprot id: A0A0K2JQY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1086726:ACH24 RS06445
gene id: 1086726:ACH24_RS06445
uniprot id: A0A0K2JSN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1086726:ACH24 RS03905
gene id: 1086726:ACH24_RS03905
uniprot id: A0A0K2JRX2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1086726:ACH24 RS00900
gene id: 1086726:ACH24_RS00900
uniprot id: A0A0K2JQJ5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1086726:ACH24 RS00315
gene id: 1086726:ACH24_RS00315
uniprot id: A0A0K2JPZ8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1086726:ACH24 RS00645
gene id: 1086726:ACH24_RS00645
uniprot id: A0A0K2JQ51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1086726:ACH24 RS04305
gene id: 1086726:ACH24_RS04305
uniprot id: A0A0K2JRR4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1086726:ACH24 RS04030
gene id: 1086726:ACH24_RS04030
uniprot id: A0A0K2JRK4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1086726:ACH24 RS04940
gene id: 1086726:ACH24_RS04940
uniprot id: A0A0K2JSD3
names: Similarity
messages: Belongs to the MlaA family.

1086726:ACH24 RS05730
gene id: 1086726:ACH24_RS05730
uniprot id: A0A0K2JSP7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1086726:ACH24 RS01190
gene id: 1086726:ACH24_RS01190
uniprot id: A0A0K2JQD9
names: Similarity
messages: Belongs to the fabD family.

1086726:ACH24 RS06595
gene id: 1086726:ACH24_RS06595
uniprot id: A0A0K2JTN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1086726:ACH24 RS05135
gene id: 1086726:ACH24_RS05135
uniprot id: A0A0K2JS31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1086726:ACH24 RS00135
gene id: 1086726:ACH24_RS00135
uniprot id: A0A0K2JPW8
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1086726:ACH24 RS01185
gene id: 1086726:ACH24_RS01185
uniprot id: A0A0K2JQP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1086726:ACH24 RS04960
gene id: 1086726:ACH24_RS04960
uniprot id: A0A0K2JS08
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1086726:ACH24 RS05215
gene id: 1086726:ACH24_RS05215
uniprot id: A0A0K2JS43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1086726:ACH24 RS01840
gene id: 1086726:ACH24_RS01840
uniprot id: A0A0K2JQM8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1086726:ACH24 RS01860
gene id: 1086726:ACH24_RS01860
uniprot id: A0A0K2JQM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

1086726:ACH24 RS04150
gene id: 1086726:ACH24_RS04150
uniprot id: A0A0K2JT46
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1086726:ACH24 RS06300
gene id: 1086726:ACH24_RS06300
uniprot id: A0A0K2JSX6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1086726:ACH24 RS03000
gene id: 1086726:ACH24_RS03000
uniprot id: A0A0K2JS35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1086726:ACH24 RS02515
gene id: 1086726:ACH24_RS02515
uniprot id: A0A0K2JQX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1086726:ACH24 RS05575
gene id: 1086726:ACH24_RS05575
uniprot id: A0A0K2JSL0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1086726:ACH24 RS04645
gene id: 1086726:ACH24_RS04645
uniprot id: A0A0K2JRW0
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1086726:ACH24 RS05125
gene id: 1086726:ACH24_RS05125
uniprot id: A0A0K2JSD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1086726:ACH24 RS05100
gene id: 1086726:ACH24_RS05100
uniprot id: A0A0K2JS21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1086726:ACH24 RS04810
gene id: 1086726:ACH24_RS04810
uniprot id: A0A0K2JS93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1086726:ACH24 RS04755
gene id: 1086726:ACH24_RS04755
uniprot id: A0A0K2JRX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1086726:ACH24 RS03510
gene id: 1086726:ACH24_RS03510
uniprot id: A0A0K2JSB7
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS00105
gene id: 1086726:ACH24_RS00105
uniprot id: A0A0K2JQT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1086726:ACH24 RS04850
gene id: 1086726:ACH24_RS04850
uniprot id: A0A0K2JRZ0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1086726:ACH24 RS01970
gene id: 1086726:ACH24_RS01970
uniprot id: A0A0K2JQP3
names: Similarity
messages: Belongs to the thioredoxin family.

1086726:ACH24 RS00955
gene id: 1086726:ACH24_RS00955
uniprot id: A0A0K2JRA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1086726:ACH24 RS01530
gene id: 1086726:ACH24_RS01530
uniprot id: A0A0K2JQI7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS02980
gene id: 1086726:ACH24_RS02980
uniprot id: A0A0K2JRI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1086726:ACH24 RS04900
gene id: 1086726:ACH24_RS04900
uniprot id: A0A0K2JRZ8
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1086726:ACH24 RS00575
gene id: 1086726:ACH24_RS00575
uniprot id: A0A0K2JQD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1086726:ACH24 RS00050
gene id: 1086726:ACH24_RS00050
uniprot id: A0A0K2JQ64
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1086726:ACH24 RS02010
gene id: 1086726:ACH24_RS02010
uniprot id: A0A0K2JRP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1086726:ACH24 RS03315
gene id: 1086726:ACH24_RS03315
uniprot id: A0A0K2JS83
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1086726:ACH24 RS03860
gene id: 1086726:ACH24_RS03860
uniprot id: A0A0K2JSH6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1086726:ACH24 RS01670
gene id: 1086726:ACH24_RS01670
uniprot id: A0A0K2JQL0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1086726:ACH24 RS00170
gene id: 1086726:ACH24_RS00170
uniprot id: A0A0K2JPX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1086726:ACH24 RS00255
gene id: 1086726:ACH24_RS00255
uniprot id: A0A0K2JPZ3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1086726:ACH24 RS04155
gene id: 1086726:ACH24_RS04155
uniprot id: A0A0K2JRN1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1086726:ACH24 RS02940
gene id: 1086726:ACH24_RS02940
uniprot id: A0A0K2JS28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1086726:ACH24 RS04525
gene id: 1086726:ACH24_RS04525
uniprot id: A0A0K2JS49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1086726:ACH24 RS00035
gene id: 1086726:ACH24_RS00035
uniprot id: A0A0K2JPV3
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS04285
gene id: 1086726:ACH24_RS04285
uniprot id: A0A0K2JRR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1086726:ACH24 RS06410
gene id: 1086726:ACH24_RS06410
uniprot id: A0A0K2JSX3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1086726:ACH24 RS03080
gene id: 1086726:ACH24_RS03080
uniprot id: A0A0K2JR71
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS00320
gene id: 1086726:ACH24_RS00320
uniprot id: A0A0K2JQX6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1086726:ACH24 RS03295
gene id: 1086726:ACH24_RS03295
uniprot id: A0A0K2JRK8
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1086726:ACH24 RS03010
gene id: 1086726:ACH24_RS03010
uniprot id: A0A0K2JRG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1086726:ACH24 RS03660
gene id: 1086726:ACH24_RS03660
uniprot id: A0A0K2JRQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1086726:ACH24 RS04700
gene id: 1086726:ACH24_RS04700
uniprot id: A0A0K2JRW8
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS01140
gene id: 1086726:ACH24_RS01140
uniprot id: A0A0K2JRC5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS01585
gene id: 1086726:ACH24_RS01585
uniprot id: A0A0K2JRI5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1086726:ACH24 RS01595
gene id: 1086726:ACH24_RS01595
uniprot id: A0A0K2JQV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1086726:ACH24 RS04110
gene id: 1086726:ACH24_RS04110
uniprot id: A0A0K2JRZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1086726:ACH24 RS03410
gene id: 1086726:ACH24_RS03410
uniprot id: A0A0K2JS99
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1086726:ACH24 RS02370
gene id: 1086726:ACH24_RS02370
uniprot id: A0A0K2JR61
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1086726:ACH24 RS02915
gene id: 1086726:ACH24_RS02915
uniprot id: A0A0K2JS24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1086726:ACH24 RS04955
gene id: 1086726:ACH24_RS04955
uniprot id: A0A0K2JS05
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

1086726:ACH24 RS02235
gene id: 1086726:ACH24_RS02235
uniprot id: A0A0K2JR47
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1086726:ACH24 RS03530
gene id: 1086726:ACH24_RS03530
uniprot id: A0A0K2JT42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1086726:ACH24 RS04490
gene id: 1086726:ACH24_RS04490
uniprot id: A0A0K2JS63
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1086726:ACH24 RS00075
gene id: 1086726:ACH24_RS00075
uniprot id: A0A0K2JQ82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1086726:ACH24 RS02840
gene id: 1086726:ACH24_RS02840
uniprot id: A0A0K2JRD4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1086726:ACH24 RS06490
gene id: 1086726:ACH24_RS06490
uniprot id: A0A0K2JTL4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1086726:ACH24 RS06095
gene id: 1086726:ACH24_RS06095
uniprot id: A0A0K2JSI9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1086726:ACH24 RS00735
gene id: 1086726:ACH24_RS00735
uniprot id: A0A0K2JQ69
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1086726:ACH24 RS03600
gene id: 1086726:ACH24_RS03600
uniprot id: A0A0K2JRS3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1086726:ACH24 RS05230
gene id: 1086726:ACH24_RS05230
uniprot id: A0A0K2JSF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1086726:ACH24 RS00380
gene id: 1086726:ACH24_RS00380
uniprot id: A0A0K2JQA9
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1086726:ACH24 RS05270
gene id: 1086726:ACH24_RS05270
uniprot id: A0A0K2JS57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1086726:ACH24 RS03505
gene id: 1086726:ACH24_RS03505
uniprot id: A0A0K2JRD1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1086726:ACH24 RS02610
gene id: 1086726:ACH24_RS02610
uniprot id: A0A0K2JQZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1086726:ACH24 RS00060
gene id: 1086726:ACH24_RS00060
uniprot id: A0A0K2JPV8
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1086726:ACH24 RS00265
gene id: 1086726:ACH24_RS00265
uniprot id: A0A0K2JQW5
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1086726:ACH24 RS05560
gene id: 1086726:ACH24_RS05560
uniprot id: A0A0K2JSA2
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1086726:ACH24 RS02150
gene id: 1086726:ACH24_RS02150
uniprot id: A0A0K2JR60
names: Similarity
messages: Belongs to the peptidase M17 family.

1086726:ACH24 RS08760
gene id: 1086726:ACH24_RS08760
uniprot id: A0A0K2JR46
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

1086726:ACH24 RS03910
gene id: 1086726:ACH24_RS03910
uniprot id: A0A0K2JRU8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1086726:ACH24 RS00920
gene id: 1086726:ACH24_RS00920
uniprot id: A0A0K2JQL4
names: Function
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1086726:ACH24 RS05485
gene id: 1086726:ACH24_RS05485
uniprot id: A0A0K2JSJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

1086726:ACH24 RS00620
gene id: 1086726:ACH24_RS00620
uniprot id: A0A0K2JQ44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1086726:ACH24 RS01195
gene id: 1086726:ACH24_RS01195
uniprot id: A0A0K2JQE3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1086726:ACH24 RS04215
gene id: 1086726:ACH24_RS04215
uniprot id: A0A0K2JRN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1086726:ACH24 RS01675
gene id: 1086726:ACH24_RS01675
uniprot id: A0A0K2JRK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1086726:ACH24 RS05300
gene id: 1086726:ACH24_RS05300
uniprot id: A0A0K2JT47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1086726:ACH24 RS04725
gene id: 1086726:ACH24_RS04725
uniprot id: A0A0K2JRW9
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS05205
gene id: 1086726:ACH24_RS05205
uniprot id: A0A0K2JS41
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1086726:ACH24 RS00455
gene id: 1086726:ACH24_RS00455
uniprot id: A0A0K2JQB6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1086726:ACH24 RS05600
gene id: 1086726:ACH24_RS05600
uniprot id: A0A0K2JSN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1086726:ACH24 RS03445
gene id: 1086726:ACH24_RS03445
uniprot id: A0A0K2JRN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1086726:ACH24 RS01685
gene id: 1086726:ACH24_RS01685
uniprot id: A0A0K2JQW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1086726:ACH24 RS01590
gene id: 1086726:ACH24_RS01590
uniprot id: A0A0K2JQX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1086726:ACH24 RS06610
gene id: 1086726:ACH24_RS06610
uniprot id: A0A0K2JSQ4
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1086726:ACH24 RS05525
gene id: 1086726:ACH24_RS05525
uniprot id: A0A0K2JS91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

1086726:ACH24 RS00585
gene id: 1086726:ACH24_RS00585
uniprot id: A0A0K2JQ40
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1086726:ACH24 RS02705
gene id: 1086726:ACH24_RS02705
uniprot id: A0A0K2JRZ6
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1086726:ACH24 RS01205
gene id: 1086726:ACH24_RS01205
uniprot id: A0A0K2JQR9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1086726:ACH24 RS01500
gene id: 1086726:ACH24_RS01500
uniprot id: A0A0K2JQI3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1086726:ACH24 RS02580
gene id: 1086726:ACH24_RS02580
uniprot id: A0A0K2JQZ0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1086726:ACH24 RS06525
gene id: 1086726:ACH24_RS06525
uniprot id: A0A0K2JSZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1086726:ACH24 RS00525
gene id: 1086726:ACH24_RS00525
uniprot id: A0A0K2JQC6
names: Subcellular Location Annotation
messages: Mitochondrion

1086726:ACH24 RS04330
gene id: 1086726:ACH24_RS04330
uniprot id: A0A0K2JRR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1086726:ACH24 RS04655
gene id: 1086726:ACH24_RS04655
uniprot id: A0A0K2JRW3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1086726:ACH24 RS03525
gene id: 1086726:ACH24_RS03525
uniprot id: A0A0K2JRD2
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

1086726:ACH24 RS00910
gene id: 1086726:ACH24_RS00910
uniprot id: A0A0K2JQ96
names: Similarity
messages: Belongs to the thioredoxin family.

1086726:ACH24 RS03255
gene id: 1086726:ACH24_RS03255
uniprot id: A0A0K2JR94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1086726:ACH24 RS05235
gene id: 1086726:ACH24_RS05235
uniprot id: A0A0K2JS45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1086726:ACH24 RS03450
gene id: 1086726:ACH24_RS03450
uniprot id: A0A0K2JRC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1086726:ACH24 RS00045
gene id: 1086726:ACH24_RS00045
uniprot id: A0A0K2JQ77
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS01515
gene id: 1086726:ACH24_RS01515
uniprot id: A0A0K2JQW6
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1086726:ACH24 RS04515
gene id: 1086726:ACH24_RS04515
uniprot id: A0A0K2JST6
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1086726:ACH24 RS04535
gene id: 1086726:ACH24_RS04535
uniprot id: A0A0K2JRU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1086726:ACH24 RS03415
gene id: 1086726:ACH24_RS03415
uniprot id: A0A0K2JRP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1086726:ACH24 RS00085
gene id: 1086726:ACH24_RS00085
uniprot id: A0A0K2JQ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1086726:ACH24 RS05700
gene id: 1086726:ACH24_RS05700
uniprot id: A0A0K2JSP4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1086726:ACH24 RS03630
gene id: 1086726:ACH24_RS03630
uniprot id: A0A0K2JRQ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1086726:ACH24 RS05140
gene id: 1086726:ACH24_RS05140
uniprot id: A0A0K2JT22
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1086726:ACH24 RS00560
gene id: 1086726:ACH24_RS00560
uniprot id: A0A0K2JQ35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1086726:ACH24 RS04315
gene id: 1086726:ACH24_RS04315
uniprot id: A0A0K2JS40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1086726:ACH24 RS03400
gene id: 1086726:ACH24_RS03400
uniprot id: A0A0K2JRB1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1086726:ACH24 RS01210
gene id: 1086726:ACH24_RS01210
uniprot id: A0A0K2JQP7
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1086726:ACH24 RS00550
gene id: 1086726:ACH24_RS00550
uniprot id: A0A0K2JQD1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1086726:ACH24 RS03650
gene id: 1086726:ACH24_RS03650
uniprot id: A0A0K2JSE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1086726:ACH24 RS05880
gene id: 1086726:ACH24_RS05880
uniprot id: A0A0K2JSS1
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS03405
gene id: 1086726:ACH24_RS03405
uniprot id: A0A0K2JRB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1086726:ACH24 RS04820
gene id: 1086726:ACH24_RS04820
uniprot id: A0A0K2JRY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1086726:ACH24 RS03435
gene id: 1086726:ACH24_RS03435
uniprot id: A0A0K2JSA5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1086726:ACH24 RS06570
gene id: 1086726:ACH24_RS06570
uniprot id: A0A0K2JT26
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1086726:ACH24 RS06555
gene id: 1086726:ACH24_RS06555
uniprot id: A0A0K2JSP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1086726:ACH24 RS05220
gene id: 1086726:ACH24_RS05220
uniprot id: A0A0K2JT37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1086726:ACH24 RS05480
gene id: 1086726:ACH24_RS05480
uniprot id: A0A0K2JSL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1086726:ACH24 RS03090
gene id: 1086726:ACH24_RS03090
uniprot id: A0A0K2JS52
names: Similarity
messages: Belongs to the RutC family.

1086726:ACH24 RS02615
gene id: 1086726:ACH24_RS02615
uniprot id: A0A0K2JRY0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

1086726:ACH24 RS00325
gene id: 1086726:ACH24_RS00325
uniprot id: A0A0K2JQB3
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1086726:ACH24 RS06645
gene id: 1086726:ACH24_RS06645
uniprot id: A0A0K2JSR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1086726:ACH24 RS02955
gene id: 1086726:ACH24_RS02955
uniprot id: A0A0K2JRF5
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

1086726:ACH24 RS00925
gene id: 1086726:ACH24_RS00925
uniprot id: A0A0K2JQL9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1086726:ACH24 RS00720
gene id: 1086726:ACH24_RS00720
uniprot id: A0A0K2JQ65
names: Similarity
messages: Belongs to the ArsC family.

1086726:ACH24 RS03545
gene id: 1086726:ACH24_RS03545
uniprot id: A0A0K2JRR2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1086726:ACH24 RS00780
gene id: 1086726:ACH24_RS00780
uniprot id: A0A0K2JQJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1086726:ACH24 RS05540
gene id: 1086726:ACH24_RS05540
uniprot id: A0A0K2JSM2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1086726:ACH24 RS05725
gene id: 1086726:ACH24_RS05725
uniprot id: A0A0K2JTA5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1086726:ACH24 RS04135
gene id: 1086726:ACH24_RS04135
uniprot id: A0A0K2JS02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

1086726:ACH24 RS01700
gene id: 1086726:ACH24_RS01700
uniprot id: A0A0K2JSS4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1086726:ACH24 RS03485
gene id: 1086726:ACH24_RS03485
uniprot id: A0A0K2JRQ3
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1086726:ACH24 RS01745
gene id: 1086726:ACH24_RS01745
uniprot id: A0A173GSL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1086726:ACH24 RS02030
gene id: 1086726:ACH24_RS02030
uniprot id: A0A0K2JQQ3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1086726:ACH24 RS01480
gene id: 1086726:ACH24_RS01480
uniprot id: A0A0K2JRH2
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

1086726:ACH24 RS02160
gene id: 1086726:ACH24_RS02160
uniprot id: A0A0K2JQS1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1086726:ACH24 RS04035
gene id: 1086726:ACH24_RS04035
uniprot id: A0A0K2JRL1
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1086726:ACH24 RS03890
gene id: 1086726:ACH24_RS03890
uniprot id: A0A0K2JTS0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1086726:ACH24 RS03615
gene id: 1086726:ACH24_RS03615
uniprot id: A0A0K2JRF6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1086726:ACH24 RS05925
gene id: 1086726:ACH24_RS05925
uniprot id: A0A0K2JST2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1086726:ACH24 RS06575
gene id: 1086726:ACH24_RS06575
uniprot id: A0A0K2JT04
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS02155
gene id: 1086726:ACH24_RS02155
uniprot id: A0A0K2JR37
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1086726:ACH24 RS00225
gene id: 1086726:ACH24_RS00225
uniprot id: A0A0K2JQ88
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1086726:ACH24 RS01230
gene id: 1086726:ACH24_RS01230
uniprot id: A0A0K2JQS3
names: Similarity
messages: Belongs to the pyruvate kinase family.

1086726:ACH24 RS04080
gene id: 1086726:ACH24_RS04080
uniprot id: A0A0K2JRX1
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1086726:ACH24 RS02645
gene id: 1086726:ACH24_RS02645
uniprot id: A0A0K2JRY5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS06495
gene id: 1086726:ACH24_RS06495
uniprot id: A0A0K2JT09
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS05145
gene id: 1086726:ACH24_RS05145
uniprot id: A0A0K2JSG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1086726:ACH24 RS03685
gene id: 1086726:ACH24_RS03685
uniprot id: A0A0K2JSF1
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

1086726:ACH24 RS05085
gene id: 1086726:ACH24_RS05085
uniprot id: A0A0K2JT13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1086726:ACH24 RS03155
gene id: 1086726:ACH24_RS03155
uniprot id: A0A0K2JRL5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1086726:ACH24 RS06600
gene id: 1086726:ACH24_RS06600
uniprot id: A0A0K2JT31
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1086726:ACH24 RS00590
gene id: 1086726:ACH24_RS00590
uniprot id: A0A0K2JR21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

1086726:ACH24 RS01655
gene id: 1086726:ACH24_RS01655
uniprot id: A0A0K2JQK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1086726:ACH24 RS02415
gene id: 1086726:ACH24_RS02415
uniprot id: A0A0K2JR93
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1086726:ACH24 RS04310
gene id: 1086726:ACH24_RS04310
uniprot id: A0A0K2JSR0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1086726:ACH24 RS06320
gene id: 1086726:ACH24_RS06320
uniprot id: A0A0K2JSL5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS01995
gene id: 1086726:ACH24_RS01995
uniprot id: A0A0K2JR14
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1086726:ACH24 RS03050
gene id: 1086726:ACH24_RS03050
uniprot id: A0A0K2JRH0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1086726:ACH24 RS01240
gene id: 1086726:ACH24_RS01240
uniprot id: A0A0K2JQE9
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1086726:ACH24 RS03625
gene id: 1086726:ACH24_RS03625
uniprot id: A0A0K2JRT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1086726:ACH24 RS04230
gene id: 1086726:ACH24_RS04230
uniprot id: A0A0K2JSN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1086726:ACH24 RS02450
gene id: 1086726:ACH24_RS02450
uniprot id: A0A0K2JR96
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1086726:ACH24 RS03320
gene id: 1086726:ACH24_RS03320
uniprot id: A0A0K2JRN4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1086726:ACH24 RS03805
gene id: 1086726:ACH24_RS03805
uniprot id: A0A0K2JRT1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1086726:ACH24 RS01155
gene id: 1086726:ACH24_RS01155
uniprot id: A0A0K2JQN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1086726:ACH24 RS03570
gene id: 1086726:ACH24_RS03570
uniprot id: A0A0K2JSC8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1086726:ACH24 RS02260
gene id: 1086726:ACH24_RS02260
uniprot id: A0A0K2JR52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1086726:ACH24 RS04615
gene id: 1086726:ACH24_RS04615
uniprot id: A0A0K2JS64
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1086726:ACH24 RS05670
gene id: 1086726:ACH24_RS05670
uniprot id: A0A0K2JSM4
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1086726:ACH24 RS00065
gene id: 1086726:ACH24_RS00065
uniprot id: A0A0K2JQT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1086726:ACH24 RS00130
gene id: 1086726:ACH24_RS00130
uniprot id: A0A0K2JPX2
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1086726:ACH24 RS06265
gene id: 1086726:ACH24_RS06265
uniprot id: A0A0K2JSX2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1086726:ACH24 RS05900
gene id: 1086726:ACH24_RS05900
uniprot id: A0A0K2JSS6
names: Similarity
messages: Belongs to the universal stress protein A family.

1086726:ACH24 RS07435
gene id: 1086726:ACH24_RS07435
uniprot id: A0A173GRK6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1086726:ACH24 RS06060
gene id: 1086726:ACH24_RS06060
uniprot id: A0A0K2JSV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1086726:ACH24 RS02295
gene id: 1086726:ACH24_RS02295
uniprot id: A0A0K2JRS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1086726:ACH24 RS00440
gene id: 1086726:ACH24_RS00440
uniprot id: A0A0K2JQ13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1086726:ACH24 RS05255
gene id: 1086726:ACH24_RS05255
uniprot id: A0A0K2JSH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1086726:ACH24 RS05200
gene id: 1086726:ACH24_RS05200
uniprot id: A0A0K2JSF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1086726:ACH24 RS04690
gene id: 1086726:ACH24_RS04690
uniprot id: A0A0K2JS74
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1086726:ACH24 RS06520
gene id: 1086726:ACH24_RS06520
uniprot id: A0A0K2JT16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1086726:ACH24 RS01505
gene id: 1086726:ACH24_RS01505
uniprot id: A0A0K2JQI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1086726:ACH24 RS04710
gene id: 1086726:ACH24_RS04710
uniprot id: A0A0K2JS97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1086726:ACH24 RS00860
gene id: 1086726:ACH24_RS00860
uniprot id: A0A0K2JR72
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1086726:ACH24 RS02130
gene id: 1086726:ACH24_RS02130
uniprot id: A0A0K2JR34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

1086726:ACH24 RS00745
gene id: 1086726:ACH24_RS00745
uniprot id: A0A0K2JR51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1086726:ACH24 RS04190
gene id: 1086726:ACH24_RS04190
uniprot id: A0A0K2JRN7
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS02455
gene id: 1086726:ACH24_RS02455
uniprot id: A0A0K2JR76
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS06375
gene id: 1086726:ACH24_RS06375
uniprot id: A0A0K2JTJ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1086726:ACH24 RS02430
gene id: 1086726:ACH24_RS02430
uniprot id: A0A0K2JQV6
names: Similarity
messages: Belongs to the peptidase S13 family.

1086726:ACH24 RS05530
gene id: 1086726:ACH24_RS05530
uniprot id: A0A0K2JS98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1086726:ACH24 RS04270
gene id: 1086726:ACH24_RS04270
uniprot id: A0A0K2JST8
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS02005
gene id: 1086726:ACH24_RS02005
uniprot id: A0A0K2JQQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1086726:ACH24 RS02830
gene id: 1086726:ACH24_RS02830
uniprot id: A0A0K2JS11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1086726:ACH24 RS06270
gene id: 1086726:ACH24_RS06270
uniprot id: A0A0K2JSV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1086726:ACH24 RS01775
gene id: 1086726:ACH24_RS01775
uniprot id: A0A0K2JQM0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1086726:ACH24 RS05850
gene id: 1086726:ACH24_RS05850
uniprot id: A0A0K2JSR6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1086726:ACH24 RS02995
gene id: 1086726:ACH24_RS02995
uniprot id: A0A0K2JR58
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1086726:ACH24 RS00215
gene id: 1086726:ACH24_RS00215
uniprot id: A0A0K2JQV3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1086726:ACH24 RS01615
gene id: 1086726:ACH24_RS01615
uniprot id: A0A0K2JT30
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS00285
gene id: 1086726:ACH24_RS00285
uniprot id: A0A0K2JPZ2
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1086726:ACH24 RS06385
gene id: 1086726:ACH24_RS06385
uniprot id: A0A0K2JSW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1086726:ACH24 RS04835
gene id: 1086726:ACH24_RS04835
uniprot id: A0A0K2JSB5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1086726:ACH24 RS04750
gene id: 1086726:ACH24_RS04750
uniprot id: A0A0K2JRX4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1086726:ACH24 RS02585
gene id: 1086726:ACH24_RS02585
uniprot id: A0A0K2JRX5
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.

1086726:ACH24 RS05180
gene id: 1086726:ACH24_RS05180
uniprot id: A0A0K2JS37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1086726:ACH24 RS00795
gene id: 1086726:ACH24_RS00795
uniprot id: A0A0K2JQ76
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1086726:ACH24 RS06470
gene id: 1086726:ACH24_RS06470
uniprot id: A0A0K2JT03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1086726:ACH24 RS01705
gene id: 1086726:ACH24_RS01705
uniprot id: A0A0K2JQL3
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1086726:ACH24 RS06415
gene id: 1086726:ACH24_RS06415
uniprot id: A0A0K2JSM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1086726:ACH24 RS01690
gene id: 1086726:ACH24_RS01690
uniprot id: A0A0K2JQK9
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1086726:ACH24 RS00545
gene id: 1086726:ACH24_RS00545
uniprot id: A0A0K2JQE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1086726:ACH24 RS00790
gene id: 1086726:ACH24_RS00790
uniprot id: A0A0K2JQ79
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1086726:ACH24 RS06485
gene id: 1086726:ACH24_RS06485
uniprot id: A0A0K2JSN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1086726:ACH24 RS02760
gene id: 1086726:ACH24_RS02760
uniprot id: A0A0K2JRE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1086726:ACH24 RS01955
gene id: 1086726:ACH24_RS01955
uniprot id: A0A0K2JRP0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1086726:ACH24 RS02750
gene id: 1086726:ACH24_RS02750
uniprot id: A0A0K2JR20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1086726:ACH24 RS01510
gene id: 1086726:ACH24_RS01510
uniprot id: A0A0K2JRH6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1086726:ACH24 RS04220
gene id: 1086726:ACH24_RS04220
uniprot id: A0A0K2JRP2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1086726:ACH24 RS02735
gene id: 1086726:ACH24_RS02735
uniprot id: A0A0K2JRE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1086726:ACH24 RS01865
gene id: 1086726:ACH24_RS01865
uniprot id: A0A0K2JQN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1086726:ACH24 RS06285
gene id: 1086726:ACH24_RS06285
uniprot id: A0A0K2JT79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1086726:ACH24 RS05810
gene id: 1086726:ACH24_RS05810
uniprot id: A0A0K2JSE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

1086726:ACH24 RS00460
gene id: 1086726:ACH24_RS00460
uniprot id: A0A0K2JQ26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1086726:ACH24 RS02065
gene id: 1086726:ACH24_RS02065
uniprot id: A0A0K2JQR6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1086726:ACH24 RS01600
gene id: 1086726:ACH24_RS01600
uniprot id: A0A0K2JQJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1086726:ACH24 RS02550
gene id: 1086726:ACH24_RS02550
uniprot id: A0A0K2JQY5
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1086726:ACH24 RS02395
gene id: 1086726:ACH24_RS02395
uniprot id: A0A0K2JR66
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1086726:ACH24 RS06275
gene id: 1086726:ACH24_RS06275
uniprot id: A0A0K2JSK2
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS02975
gene id: 1086726:ACH24_RS02975
uniprot id: A0A0K2JS30
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1086726:ACH24 RS01620
gene id: 1086726:ACH24_RS01620
uniprot id: A0A0K2JQY0
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1086726:ACH24 RS06580
gene id: 1086726:ACH24_RS06580
uniprot id: A0A0K2JSX1
names: Similarity
messages: Belongs to the citrate synthase family.

1086726:ACH24 RS00650
gene id: 1086726:ACH24_RS00650
uniprot id: A0A0K2JR33
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1086726:ACH24 RS00965
gene id: 1086726:ACH24_RS00965
uniprot id: A0A0K2JQM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS02920
gene id: 1086726:ACH24_RS02920
uniprot id: A0A0K2JRH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1086726:ACH24 RS04255
gene id: 1086726:ACH24_RS04255
uniprot id: A0A0K2JSQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1086726:ACH24 RS00630
gene id: 1086726:ACH24_RS00630
uniprot id: A0A0K2JQG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1086726:ACH24 RS06205
gene id: 1086726:ACH24_RS06205
uniprot id: A0A0K2JSW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

1086726:ACH24 RS03005
gene id: 1086726:ACH24_RS03005
uniprot id: A0A0K2JRI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1086726:ACH24 RS04625
gene id: 1086726:ACH24_RS04625
uniprot id: A0A0K2JRW1
names: Similarity
messages: Belongs to the GARS family.
messages: Belongs to the SAICAR synthetase family.

1086726:ACH24 RS01885
gene id: 1086726:ACH24_RS01885
uniprot id: A0A0K2JQN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1086726:ACH24 RS03790
gene id: 1086726:ACH24_RS03790
uniprot id: A0A0K2JRI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

1086726:ACH24 RS06530
gene id: 1086726:ACH24_RS06530
uniprot id: A0A0K2JSP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1086726:ACH24 RS02770
gene id: 1086726:ACH24_RS02770
uniprot id: A0A0K2JR18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

1086726:ACH24 RS03770
gene id: 1086726:ACH24_RS03770
uniprot id: A0A0K2JSG1
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1086726:ACH24 RS02630
gene id: 1086726:ACH24_RS02630
uniprot id: A0A0K2JRA0
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1086726:ACH24 RS02145
gene id: 1086726:ACH24_RS02145
uniprot id: A0A0K2JRR0
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1086726:ACH24 RS05015
gene id: 1086726:ACH24_RS05015
uniprot id: A0A0K2JSE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1086726:ACH24 RS03365
gene id: 1086726:ACH24_RS03365
uniprot id: A0A0K2JRL7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1086726:ACH24 RS05120
gene id: 1086726:ACH24_RS05120
uniprot id: A0A173GR45
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1086726:ACH24 RS00530
gene id: 1086726:ACH24_RS00530
uniprot id: A0A0K2JQ36
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1086726:ACH24 RS02445
gene id: 1086726:ACH24_RS02445
uniprot id: A0A0K2JRU9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1086726:ACH24 RS05115
gene id: 1086726:ACH24_RS05115
uniprot id: A0A0K2JSF5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1086726:ACH24 RS00615
gene id: 1086726:ACH24_RS00615
uniprot id: A0A0K2JQ50
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1086726:ACH24 RS01520
gene id: 1086726:ACH24_RS01520
uniprot id: A0A0K2JQU4
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1086726:ACH24 RS01750
gene id: 1086726:ACH24_RS01750
uniprot id: A0A0K2JQL7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1086726:ACH24 RS06035
gene id: 1086726:ACH24_RS06035
uniprot id: A0A0K2JSI0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1086726:ACH24 RS05185
gene id: 1086726:ACH24_RS05185
uniprot id: A0A0K2JS38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1086726:ACH24 RS00655
gene id: 1086726:ACH24_RS00655
uniprot id: A0A0K2JQH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1086726:ACH24 RS02500
gene id: 1086726:ACH24_RS02500
uniprot id: A0A0K2JRA3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1086726:ACH24 RS05110
gene id: 1086726:ACH24_RS05110
uniprot id: A0A0K2JT17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1086726:ACH24 RS05820
gene id: 1086726:ACH24_RS05820
uniprot id: A0A0K2JSR1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1086726:ACH24 RS01550
gene id: 1086726:ACH24_RS01550
uniprot id: A0A0K2JQX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1086726:ACH24 RS05260
gene id: 1086726:ACH24_RS05260
uniprot id: A0A0K2JSG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1086726:ACH24 RS02680
gene id: 1086726:ACH24_RS02680
uniprot id: A0A0K2JRA8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1086726:ACH24 RS03655
gene id: 1086726:ACH24_RS03655
uniprot id: A0A0K2JRT6
names: Similarity
messages: Belongs to the PhoH family.

1086726:ACH24 RS03690
gene id: 1086726:ACH24_RS03690
uniprot id: A0A0K2JRU0
names: Similarity
messages: Belongs to the peptidase M24B family.

1086726:ACH24 RS06305
gene id: 1086726:ACH24_RS06305
uniprot id: A0A0K2JSV9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1086726:ACH24 RS04435
gene id: 1086726:ACH24_RS04435
uniprot id: A0A0K2JS53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1086726:ACH24 RS03730
gene id: 1086726:ACH24_RS03730
uniprot id: A0A0K2JRU5
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1086726:ACH24 RS00260
gene id: 1086726:ACH24_RS00260
uniprot id: A0A0K2JPZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1086726:ACH24 RS03775
gene id: 1086726:ACH24_RS03775
uniprot id: A0A0K2JRV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1086726:ACH24 RS01905
gene id: 1086726:ACH24_RS01905
uniprot id: A0A0K2JR22
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1086726:ACH24 RS00250
gene id: 1086726:ACH24_RS00250
uniprot id: A0A0K2JQ93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1086726:ACH24 RS00240
gene id: 1086726:ACH24_RS00240
uniprot id: A0A0K2JQV9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1086726:ACH24 RS04045
gene id: 1086726:ACH24_RS04045
uniprot id: A0A0K2JRY7
names: Similarity
messages: Belongs to the LOG family.

1086726:ACH24 RS06540
gene id: 1086726:ACH24_RS06540
uniprot id: A0A0K2JTM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1086726:ACH24 RS00725
gene id: 1086726:ACH24_RS00725
uniprot id: A0A0K2JQ61
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1086726:ACH24 RS04745
gene id: 1086726:ACH24_RS04745
uniprot id: A0A0K2JS84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1086726:ACH24 RS05970
gene id: 1086726:ACH24_RS05970
uniprot id: A0A0K2JSH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1086726:ACH24 RS02745
gene id: 1086726:ACH24_RS02745
uniprot id: A0A0K2JR13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1086726:ACH24 RS01765
gene id: 1086726:ACH24_RS01765
uniprot id: A0A0K2JQX8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1086726:ACH24 RS01525
gene id: 1086726:ACH24_RS01525
uniprot id: A0A0K2JT49
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1086726:ACH24 RS01110
gene id: 1086726:ACH24_RS01110
uniprot id: A0A0K2JQN5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1086726:ACH24 RS05620
gene id: 1086726:ACH24_RS05620
uniprot id: A0A0K2JT89
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

1086726:ACH24 RS02860
gene id: 1086726:ACH24_RS02860
uniprot id: A0A0K2JRG4
names: Similarity
messages: Belongs to the HesB/IscA family.

1086726:ACH24 RS04885
gene id: 1086726:ACH24_RS04885
uniprot id: A0A0K2JSY6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1086726:ACH24 RS02045
gene id: 1086726:ACH24_RS02045
uniprot id: A0A0K2JRP9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1086726:ACH24 RS06545
gene id: 1086726:ACH24_RS06545
uniprot id: A0A0K2JT21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1086726:ACH24 RS04555
gene id: 1086726:ACH24_RS04555
uniprot id: A0A0K2JRU6
names: Similarity
messages: Belongs to the ParB family.

1086726:ACH24 RS02960
gene id: 1086726:ACH24_RS02960
uniprot id: A0A0K2JR48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1086726:ACH24 RS05330
gene id: 1086726:ACH24_RS05330
uniprot id: A0A0K2JS67
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1086726:ACH24 RS05060
gene id: 1086726:ACH24_RS05060
uniprot id: A0A0K2JSV5
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1086726:ACH24 RS00800
gene id: 1086726:ACH24_RS00800
uniprot id: A0A0K2JR62
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1086726:ACH24 RS02570
gene id: 1086726:ACH24_RS02570
uniprot id: A0A0K2JQY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1086726:ACH24 RS02890
gene id: 1086726:ACH24_RS02890
uniprot id: A0A0K2JRG9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1086726:ACH24 RS00540
gene id: 1086726:ACH24_RS00540
uniprot id: A0A0K2JR10
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1086726:ACH24 RS04770
gene id: 1086726:ACH24_RS04770
uniprot id: A0A0K2JS88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1086726:ACH24 RS06085
gene id: 1086726:ACH24_RS06085
uniprot id: A0A0K2JSI5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1086726:ACH24 RS04620
gene id: 1086726:ACH24_RS04620
uniprot id: A0A0K2JRV5
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1086726:ACH24 RS05345
gene id: 1086726:ACH24_RS05345
uniprot id: A0A0K2JSH7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1086726:ACH24 RS01115
gene id: 1086726:ACH24_RS01115
uniprot id: A0A0K2JQD2
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1086726:ACH24 RS00335
gene id: 1086726:ACH24_RS00335
uniprot id: A0A0K2JSS3
names: Similarity
messages: Belongs to the UPF0246 family.

1086726:ACH24 RS06480
gene id: 1086726:ACH24_RS06480
uniprot id: A0A0K2JSN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1086726:ACH24 RS00245
gene id: 1086726:ACH24_RS00245
uniprot id: A0A0K2JQA4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1086726:ACH24 RS05155
gene id: 1086726:ACH24_RS05155
uniprot id: A0A0K2JS29
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1086726:ACH24 RS02715
gene id: 1086726:ACH24_RS02715
uniprot id: A0A0K2JRB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1086726:ACH24 RS01395
gene id: 1086726:ACH24_RS01395
uniprot id: A0A0K2JQG9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1086726:ACH24 RS05285
gene id: 1086726:ACH24_RS05285
uniprot id: A0A0K2JSG8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

1086726:ACH24 RS04890
gene id: 1086726:ACH24_RS04890
uniprot id: A0A0K2JSC4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1086726:ACH24 RS00555
gene id: 1086726:ACH24_RS00555
uniprot id: A0A0K2JQ41
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS01925
gene id: 1086726:ACH24_RS01925
uniprot id: A0A0K2JQP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1086726:ACH24 RS04395
gene id: 1086726:ACH24_RS04395
uniprot id: A0A0K2JS32
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS02885
gene id: 1086726:ACH24_RS02885
uniprot id: A0A0K2JS19
names: Subcellular Location Annotation
messages: Membrane

1086726:ACH24 RS01930
gene id: 1086726:ACH24_RS01930
uniprot id: A0A0K2JRN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1086726:ACH24 RS04915
gene id: 1086726:ACH24_RS04915
uniprot id: A0A0K2JSD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1086726:ACH24 RS03345
gene id: 1086726:ACH24_RS03345
uniprot id: A0A0K2JRA5
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1086726:ACH24 RS06535
gene id: 1086726:ACH24_RS06535
uniprot id: A0A0K2JSP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1086726:ACH24 RS03850
gene id: 1086726:ACH24_RS03850
uniprot id: A0A0K2JRI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1086726:ACH24 RS03385
gene id: 1086726:ACH24_RS03385
uniprot id: A0A0K2JS94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1086726:ACH24 RS01950
gene id: 1086726:ACH24_RS01950
uniprot id: A0A0K2JQP6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1086726:ACH24 RS05800
gene id: 1086726:ACH24_RS05800
uniprot id: A0A0K2JSP1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1086726:ACH24 RS02310
gene id: 1086726:ACH24_RS02310
uniprot id: A0A0K2JR56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1086726:ACH24 RS05280
gene id: 1086726:ACH24_RS05280
uniprot id: A0A0K2JSI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1086726:ACH24 RS04865
gene id: 1086726:ACH24_RS04865
uniprot id: A0A0K2JSC0
names: Similarity
messages: Belongs to the ArsC family.

1086726:ACH24 RS01635
gene id: 1086726:ACH24_RS01635
uniprot id: A0A0K2JQK3
names: Similarity
messages: Belongs to the peptidase S49 family.

1086726:ACH24 RS02060
gene id: 1086726:ACH24_RS02060
uniprot id: A0A0K2JQQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1086726:ACH24 RS03710
gene id: 1086726:ACH24_RS03710
uniprot id: A0A0K2JSF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class A bacterial acid phosphatase family.
messages: Periplasm

1086726:ACH24 RS04990
gene id: 1086726:ACH24_RS04990
uniprot id: A0A0K2JSB9
names: Similarity
messages: Belongs to the FBPase class 2 family.

1086726:ACH24 RS05325
gene id: 1086726:ACH24_RS05325
uniprot id: A0A0K2JS59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1086726:ACH24 RS00940
gene id: 1086726:ACH24_RS00940
uniprot id: A0A0K2JQB5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1086726:ACH24 RS02175
gene id: 1086726:ACH24_RS02175
uniprot id: A0A0K2JRR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1086726:ACH24 RS05295
gene id: 1086726:ACH24_RS05295
uniprot id: A0A0K2JS60
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS04450
gene id: 1086726:ACH24_RS04450
uniprot id: A0A0K2JRT2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1086726:ACH24 RS06605
gene id: 1086726:ACH24_RS06605
uniprot id: A0A0K2JT08
names: Function
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1086726:ACH24 RS01800
gene id: 1086726:ACH24_RS01800
uniprot id: A0A0K2JQY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1086726:ACH24 RS03875
gene id: 1086726:ACH24_RS03875
uniprot id: A0A0K2JRI7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1086726:ACH24 RS02925
gene id: 1086726:ACH24_RS02925
uniprot id: A0A0K2JRE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1086726:ACH24 RS02405
gene id: 1086726:ACH24_RS02405
uniprot id: A0A0K2JQW0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1086726:ACH24 RS04730
gene id: 1086726:ACH24_RS04730
uniprot id: A0A0K2JRX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1086726:ACH24 RS00505
gene id: 1086726:ACH24_RS00505
uniprot id: A0A0K2JR05
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1086726:ACH24 RS05720
gene id: 1086726:ACH24_RS05720
uniprot id: A0A0K2JSC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1086726:ACH24 RS01880
gene id: 1086726:ACH24_RS01880
uniprot id: A0A0K2JQZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1086726:ACH24 RS05210
gene id: 1086726:ACH24_RS05210
uniprot id: A0A0K2JT68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1086726:ACH24 RS00770
gene id: 1086726:ACH24_RS00770
uniprot id: A0A0K2JQ71
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1086726:ACH24 RS02400
gene id: 1086726:ACH24_RS02400
uniprot id: A0A0K2JQV1
names: Similarity
messages: Belongs to the UPF0250 family.

1086726:ACH24 RS02250
gene id: 1086726:ACH24_RS02250
uniprot id: A0A0K2JRS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1086726:ACH24 RS02390
gene id: 1086726:ACH24_RS02390
uniprot id: A0A0K2JR89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1086726:ACH24 RS06175
gene id: 1086726:ACH24_RS06175
uniprot id: A0A0K2JSJ3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1086726:ACH24 RS01200
gene id: 1086726:ACH24_RS01200
uniprot id: A0A0K2JRD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1086726:ACH24 RS02780
gene id: 1086726:ACH24_RS02780
uniprot id: A0A0K2JS07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1086726:ACH24 RS01910
gene id: 1086726:ACH24_RS01910
uniprot id: A0A0K2JTR2
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1086726:ACH24 RS05175
gene id: 1086726:ACH24_RS05175
uniprot id: A0A0K2JSE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1086726:ACH24 RS00995
gene id: 1086726:ACH24_RS00995
uniprot id: A0A0K2JQB9
names: Similarity
messages: Belongs to the NusB family.

1086726:ACH24 RS01175
gene id: 1086726:ACH24_RS01175
uniprot id: A0A0K2JRC9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1086726:ACH24 RS06460
gene id: 1086726:ACH24_RS06460
uniprot id: A0A0K2JTK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1086726:ACH24 RS00610
gene id: 1086726:ACH24_RS00610
uniprot id: A0A0K2JQE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
messages: Membrane

1086726:ACH24 RS02805
gene id: 1086726:ACH24_RS02805
uniprot id: A0A0K2JR23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

1086726:ACH24 RS02765
gene id: 1086726:ACH24_RS02765
uniprot id: A0A0K2JRC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1086726:ACH24 RS00330
gene id: 1086726:ACH24_RS00330
uniprot id: A0A0K2JQA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1086726:ACH24 RS00605
gene id: 1086726:ACH24_RS00605
uniprot id: A0A0K2JQF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1086726:ACH24 RS05815
gene id: 1086726:ACH24_RS05815
uniprot id: A0A0K2JTC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1086726:ACH24 RS05305
gene id: 1086726:ACH24_RS05305
uniprot id: A0A0K2JSI8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1086726:ACH24 RS05160
gene id: 1086726:ACH24_RS05160
uniprot id: A0A0K2JS33
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1086726:ACH24 RS00905
gene id: 1086726:ACH24_RS00905
uniprot id: A0A0K2JQ99
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.