1069220:G6N11 RS12455
gene id: 1069220:G6N11_RS12455
uniprot id: A0A7I7SH10
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1069220:G6N11 RS19420
gene id: 1069220:G6N11_RS19420
uniprot id: A0A7I7SIP7
names: Similarity
messages: Belongs to the FPG family.

1069220:G6N11 RS03995
gene id: 1069220:G6N11_RS03995
uniprot id: A0A7I7SAZ0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1069220:G6N11 RS12385
gene id: 1069220:G6N11_RS12385
uniprot id: A0A7I7SE57
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1069220:G6N11 RS15625
gene id: 1069220:G6N11_RS15625
uniprot id: A0A7I7SGI5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1069220:G6N11 RS09175
gene id: 1069220:G6N11_RS09175
uniprot id: A0A7I7SCX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1069220:G6N11 RS01800
gene id: 1069220:G6N11_RS01800
uniprot id: A0A7I7S9R8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1069220:G6N11 RS17625
gene id: 1069220:G6N11_RS17625
uniprot id: A0A7I7SIM1
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1069220:G6N11 RS08650
gene id: 1069220:G6N11_RS08650
uniprot id: A0A7I7SC15
names: Similarity
messages: Belongs to the P(II) protein family.

1069220:G6N11 RS21210
gene id: 1069220:G6N11_RS21210
uniprot id: A0A7I7SK62
names: Similarity
messages: Belongs to the mycobacterial PPE family.

1069220:G6N11 RS18275
gene id: 1069220:G6N11_RS18275
uniprot id: A0A7I7SHK9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1069220:G6N11 RS11150
gene id: 1069220:G6N11_RS11150
uniprot id: A0A7I7SDT5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1069220:G6N11 RS04460
gene id: 1069220:G6N11_RS04460
uniprot id: A0A7I7S9T1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1069220:G6N11 RS18505
gene id: 1069220:G6N11_RS18505
uniprot id: A0A7I7SJ35
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1069220:G6N11 RS16115
gene id: 1069220:G6N11_RS16115
uniprot id: A0A7I7SGT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccD/Snm4 family.
messages: Membrane

1069220:G6N11 RS12250
gene id: 1069220:G6N11_RS12250
uniprot id: A0A7I7SE40
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1069220:G6N11 RS00415
gene id: 1069220:G6N11_RS00415
uniprot id: A0A7I7S807
names: Similarity
messages: Belongs to the peptidase S1C family.

1069220:G6N11 RS11610
gene id: 1069220:G6N11_RS11610
uniprot id: A0A7I7SE32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1069220:G6N11 RS13315
gene id: 1069220:G6N11_RS13315
uniprot id: A0A7I7SGN8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1069220:G6N11 RS12390
gene id: 1069220:G6N11_RS12390
uniprot id: A0A7I7SEN1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1069220:G6N11 RS00895
gene id: 1069220:G6N11_RS00895
uniprot id: A0A7I7S7S1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1069220:G6N11 RS11460
gene id: 1069220:G6N11_RS11460
uniprot id: A0A7I7SFL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1069220:G6N11 RS17845
gene id: 1069220:G6N11_RS17845
uniprot id: A0A7I7SHB9
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1069220:G6N11 RS19875
gene id: 1069220:G6N11_RS19875
uniprot id: A0A7I7SID6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1069220:G6N11 RS00735
gene id: 1069220:G6N11_RS00735
uniprot id: A0A7I7S9K7
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1069220:G6N11 RS16665
gene id: 1069220:G6N11_RS16665
uniprot id: A0A7I7SHP9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1069220:G6N11 RS03285
gene id: 1069220:G6N11_RS03285
uniprot id: A0A7I7S944
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

1069220:G6N11 RS08665
gene id: 1069220:G6N11_RS08665
uniprot id: A0A7I7SC25
names: Similarity
messages: Belongs to the acylphosphatase family.

1069220:G6N11 RS04020
gene id: 1069220:G6N11_RS04020
uniprot id: A0A7I7SBI4
names: Subcellular Location Annotation
messages: Membrane

1069220:G6N11 RS12075
gene id: 1069220:G6N11_RS12075
uniprot id: A0A7I7SFZ7
names: Subcellular Location Annotation
messages: Membrane

1069220:G6N11 RS04065
gene id: 1069220:G6N11_RS04065
uniprot id: A0A7I7SC27
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1069220:G6N11 RS04015
gene id: 1069220:G6N11_RS04015
uniprot id: A0A7I7SC20
names: Subcellular Location Annotation
messages: Membrane

1069220:G6N11 RS04540
gene id: 1069220:G6N11_RS04540
uniprot id: A0A7I7SA39
names: Similarity
messages: Belongs to the UPF0235 family.

1069220:G6N11 RS00525
gene id: 1069220:G6N11_RS00525
uniprot id: A0A7I7SA35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1069220:G6N11 RS04395
gene id: 1069220:G6N11_RS04395
uniprot id: A0A7I7SBF1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1069220:G6N11 RS03050
gene id: 1069220:G6N11_RS03050
uniprot id: A0A7I7S905
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1069220:G6N11 RS02085
gene id: 1069220:G6N11_RS02085
uniprot id: A0A7I7S8G8
names: Subcellular Location Annotation
messages: Membrane

1069220:G6N11 RS15455
gene id: 1069220:G6N11_RS15455
uniprot id: A0A7I7SGY3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1069220:G6N11 RS00785
gene id: 1069220:G6N11_RS00785
uniprot id: A0A7I7S7Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1069220:G6N11 RS08930
gene id: 1069220:G6N11_RS08930
uniprot id: A0A7I7SDQ3
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1069220:G6N11 RS03215
gene id: 1069220:G6N11_RS03215
uniprot id: A0A7I7S9D5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

1069220:G6N11 RS13295
gene id: 1069220:G6N11_RS13295
uniprot id: A0A7I7SEP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1069220:G6N11 RS11285
gene id: 1069220:G6N11_RS11285
uniprot id: A0A7I7SDJ5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1069220:G6N11 RS16490
gene id: 1069220:G6N11_RS16490
uniprot id: A0A7I7SGJ3
names: Similarity
messages: Belongs to the AccD/PCCB family.

1069220:G6N11 RS08630
gene id: 1069220:G6N11_RS08630
uniprot id: A0A7I7SD80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1069220:G6N11 RS19855
gene id: 1069220:G6N11_RS19855
uniprot id: A0A7I7SIE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1069220:G6N11 RS11425
gene id: 1069220:G6N11_RS11425
uniprot id: A0A7I7SDL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1069220:G6N11 RS18145
gene id: 1069220:G6N11_RS18145
uniprot id: A0A7I7SHS8
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1069220:G6N11 RS20135
gene id: 1069220:G6N11_RS20135
uniprot id: A0A7I7SKH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1069220:G6N11 RS03720
gene id: 1069220:G6N11_RS03720
uniprot id: A0A7I7S9C9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1069220:G6N11 RS00645
gene id: 1069220:G6N11_RS00645
uniprot id: A0A7I7S981
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1069220:G6N11 RS21125
gene id: 1069220:G6N11_RS21125
uniprot id: A0A7I7SE25
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

1069220:G6N11 RS20170
gene id: 1069220:G6N11_RS20170
uniprot id: A0A7I7SLG7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1069220:G6N11 RS02480
gene id: 1069220:G6N11_RS02480
uniprot id: A0A7I7S8P7
names: Similarity
messages: Belongs to the glutamine synthetase family.

1069220:G6N11 RS02355
gene id: 1069220:G6N11_RS02355
uniprot id: A0A7I7SA38
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Acyl carrier protein involved in meromycolate extension.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1069220:G6N11 RS11750
gene id: 1069220:G6N11_RS11750
uniprot id: A0A7I7SEA3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1069220:G6N11 RS03515
gene id: 1069220:G6N11_RS03515
uniprot id: A0A7I7S9J5
names: Subcellular Location Annotation
messages: Membrane

1069220:G6N11 RS18705
gene id: 1069220:G6N11_RS18705
uniprot id: A0A7I7SHU0
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1069220:G6N11 RS01755
gene id: 1069220:G6N11_RS01755
uniprot id: A0A7I7S8A0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1069220:G6N11 RS12220
gene id: 1069220:G6N11_RS12220
uniprot id: A0A7I7SEE3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1069220:G6N11 RS13595
gene id: 1069220:G6N11_RS13595
uniprot id: A0A7I7SGU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1069220:G6N11 RS04685
gene id: 1069220:G6N11_RS04685
uniprot id: A0A7I7S9X1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1069220:G6N11 RS18495
gene id: 1069220:G6N11_RS18495
uniprot id: A0A7I7SJM0
names: Similarity
messages: Belongs to the cytochrome P450 family.

1069220:G6N11 RS11450
gene id: 1069220:G6N11_RS11450
uniprot id: A0A7I7SDL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1069220:G6N11 RS15450
gene id: 1069220:G6N11_RS15450
uniprot id: A0A7I7SHV3
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1069220:G6N11 RS11255
gene id: 1069220:G6N11_RS11255
uniprot id: A0A7I7SDV5
names: Similarity
messages: Belongs to the HIBADH-related family.

1069220:G6N11 RS07815
gene id: 1069220:G6N11_RS07815
uniprot id: A0A7I7SBN4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS11535
gene id: 1069220:G6N11_RS11535
uniprot id: A0A7I7SE71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1069220:G6N11 RS08510
gene id: 1069220:G6N11_RS08510
uniprot id: A0A7I7SEC2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1069220:G6N11 RS10825
gene id: 1069220:G6N11_RS10825
uniprot id: A0A7I7SDS7
names: Similarity
messages: Belongs to the universal stress protein A family.

1069220:G6N11 RS09655
gene id: 1069220:G6N11_RS09655
uniprot id: A0A7I7SF94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1069220:G6N11 RS19765
gene id: 1069220:G6N11_RS19765
uniprot id: A0A7I7SL12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1069220:G6N11 RS01820
gene id: 1069220:G6N11_RS01820
uniprot id: A0A7I7SAT9
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1069220:G6N11 RS14255
gene id: 1069220:G6N11_RS14255
uniprot id: A0A7I7SF67
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1069220:G6N11 RS12700
gene id: 1069220:G6N11_RS12700
uniprot id: A0A7I7SEC9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1069220:G6N11 RS16330
gene id: 1069220:G6N11_RS16330
uniprot id: A0A7I7SHG2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

1069220:G6N11 RS05220
gene id: 1069220:G6N11_RS05220
uniprot id: A0A7I7SA68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1069220:G6N11 RS08480
gene id: 1069220:G6N11_RS08480
uniprot id: A0A7I7SD48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1069220:G6N11 RS19435
gene id: 1069220:G6N11_RS19435
uniprot id: A0A7I7SL14
names: Similarity
messages: Belongs to the mycobacterial PPE family.

1069220:G6N11 RS02000
gene id: 1069220:G6N11_RS02000
uniprot id: A0A7I7S9W5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1069220:G6N11 RS01095
gene id: 1069220:G6N11_RS01095
uniprot id: A0A7I7S7W8
names: Subcellular Location Annotation
messages: Membrane

1069220:G6N11 RS10775
gene id: 1069220:G6N11_RS10775
uniprot id: A0A7I7SDR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1069220:G6N11 RS18775
gene id: 1069220:G6N11_RS18775
uniprot id: A0A7I7SKN3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1069220:G6N11 RS18485
gene id: 1069220:G6N11_RS18485
uniprot id: A0A7I7SHL5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1069220:G6N11 RS11440
gene id: 1069220:G6N11_RS11440
uniprot id: A0A7I7SG90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1069220:G6N11 RS12210
gene id: 1069220:G6N11_RS12210
uniprot id: A0A7I7SGQ0
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

1069220:G6N11 RS09045
gene id: 1069220:G6N11_RS09045
uniprot id: A0A7I7SCA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1069220:G6N11 RS01625
gene id: 1069220:G6N11_RS01625
uniprot id: A0A7I7SA52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1069220:G6N11 RS05225
gene id: 1069220:G6N11_RS05225
uniprot id: A0A7I7SCP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1069220:G6N11 RS04660
gene id: 1069220:G6N11_RS04660
uniprot id: A0A7I7S9W4
names: Similarity
messages: Belongs to the TrpC family.

1069220:G6N11 RS11200
gene id: 1069220:G6N11_RS11200
uniprot id: A0A7I7SDU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1069220:G6N11 RS01135
gene id: 1069220:G6N11_RS01135
uniprot id: A0A7I7S7Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EspG family.
messages: Cytoplasm

1069220:G6N11 RS02010
gene id: 1069220:G6N11_RS02010
uniprot id: A0A7I7S8X6
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1069220:G6N11 RS02365
gene id: 1069220:G6N11_RS02365
uniprot id: A0A7I7S955
names: Similarity
messages: Belongs to the CdaR family.

1069220:G6N11 RS12160
gene id: 1069220:G6N11_RS12160
uniprot id: A0A7I7SGN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1069220:G6N11 RS08140
gene id: 1069220:G6N11_RS08140
uniprot id: A0A7I7SBT4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS09370
gene id: 1069220:G6N11_RS09370
uniprot id: A0A7I7SDL8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1069220:G6N11 RS17825
gene id: 1069220:G6N11_RS17825
uniprot id: A0A7I7SIR0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1069220:G6N11 RS05030
gene id: 1069220:G6N11_RS05030
uniprot id: A0A7I7SC98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1069220:G6N11 RS14830
gene id: 1069220:G6N11_RS14830
uniprot id: A0A7I7SHH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1069220:G6N11 RS13095
gene id: 1069220:G6N11_RS13095
uniprot id: A0A7I7SEK2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1069220:G6N11 RS00640
gene id: 1069220:G6N11_RS00640
uniprot id: A0A7I7S7T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1069220:G6N11 RS14070
gene id: 1069220:G6N11_RS14070
uniprot id: A0A7I7SHS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EspG family.
messages: Cytoplasm

1069220:G6N11 RS14835
gene id: 1069220:G6N11_RS14835
uniprot id: A0A7I7SGL0
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1069220:G6N11 RS17745
gene id: 1069220:G6N11_RS17745
uniprot id: A0A7I7SJY8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS05205
gene id: 1069220:G6N11_RS05205
uniprot id: A0A7I7SBL5
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1069220:G6N11 RS02540
gene id: 1069220:G6N11_RS02540
uniprot id: A0A7I7SAP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1069220:G6N11 RS19820
gene id: 1069220:G6N11_RS19820
uniprot id: A0A7I7SIC6
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1069220:G6N11 RS03125
gene id: 1069220:G6N11_RS03125
uniprot id: A0A7I7SAI1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1069220:G6N11 RS19975
gene id: 1069220:G6N11_RS19975
uniprot id: A0A7I7SIF6
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1069220:G6N11 RS01170
gene id: 1069220:G6N11_RS01170
uniprot id: A0A1X2LLG0
names: Similarity
messages: Belongs to the WXG100 family.

1069220:G6N11 RS17170
gene id: 1069220:G6N11_RS17170
uniprot id: A0A7I7SGY5
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

1069220:G6N11 RS19115
gene id: 1069220:G6N11_RS19115
uniprot id: A0A7I7SJ77
names: Similarity
messages: Belongs to the citrate synthase family.

1069220:G6N11 RS02465
gene id: 1069220:G6N11_RS02465
uniprot id: A0A7I7SA61
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1069220:G6N11 RS17610
gene id: 1069220:G6N11_RS17610
uniprot id: A0A7I7SHG9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1069220:G6N11 RS17685
gene id: 1069220:G6N11_RS17685
uniprot id: A0A7I7SHR8
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

1069220:G6N11 RS05610
gene id: 1069220:G6N11_RS05610
uniprot id: A0A7I7SAX3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1069220:G6N11 RS04150
gene id: 1069220:G6N11_RS04150
uniprot id: A0A7I7S9L9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1069220:G6N11 RS09695
gene id: 1069220:G6N11_RS09695
uniprot id: A0A7I7SD65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1069220:G6N11 RS02655
gene id: 1069220:G6N11_RS02655
uniprot id: A0A7I7SAG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

1069220:G6N11 RS17680
gene id: 1069220:G6N11_RS17680
uniprot id: A0A7I7SH92
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1069220:G6N11 RS00775
gene id: 1069220:G6N11_RS00775
uniprot id: A0A7I7SA83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1069220:G6N11 RS11215
gene id: 1069220:G6N11_RS11215
uniprot id: A0A7I7SEK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1069220:G6N11 RS18970
gene id: 1069220:G6N11_RS18970
uniprot id: A0A7I7SJB6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1069220:G6N11 RS04480
gene id: 1069220:G6N11_RS04480
uniprot id: A0A7I7SBY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1069220:G6N11 RS00765
gene id: 1069220:G6N11_RS00765
uniprot id: A0A7I7S878
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1069220:G6N11 RS10645
gene id: 1069220:G6N11_RS10645
uniprot id: A0A7I7SFQ6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1069220:G6N11 RS02575
gene id: 1069220:G6N11_RS02575
uniprot id: A0A7I7S9A3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1069220:G6N11 RS05305
gene id: 1069220:G6N11_RS05305
uniprot id: A0A7I7SBN3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1069220:G6N11 RS07730
gene id: 1069220:G6N11_RS07730
uniprot id: A0A7I7SDC6
names: Subcellular Location Annotation
messages: Membrane

1069220:G6N11 RS15485
gene id: 1069220:G6N11_RS15485
uniprot id: A0A7I7SIJ7
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1069220:G6N11 RS02500
gene id: 1069220:G6N11_RS02500
uniprot id: A0A7I7S8Z3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS18740
gene id: 1069220:G6N11_RS18740
uniprot id: A0A7I7SJR6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1069220:G6N11 RS04265
gene id: 1069220:G6N11_RS04265
uniprot id: A0A7I7SC68
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1069220:G6N11 RS15050
gene id: 1069220:G6N11_RS15050
uniprot id: A0A7I7SFP0
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

1069220:G6N11 RS16945
gene id: 1069220:G6N11_RS16945
uniprot id: A0A7I7SGT2
names: Subcellular Location Annotation
messages: Membrane

1069220:G6N11 RS11160
gene id: 1069220:G6N11_RS11160
uniprot id: A0A7I7SEJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1069220:G6N11 RS04915
gene id: 1069220:G6N11_RS04915
uniprot id: A0A7I7SAH7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1069220:G6N11 RS08255
gene id: 1069220:G6N11_RS08255
uniprot id: A0A7I7SBT7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1069220:G6N11 RS16160
gene id: 1069220:G6N11_RS16160
uniprot id: A0A7I7SGB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

1069220:G6N11 RS20465
gene id: 1069220:G6N11_RS20465
uniprot id: A0A7I7SJ97
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1069220:G6N11 RS02340
gene id: 1069220:G6N11_RS02340
uniprot id: A0A7I7S8V2
names: Similarity
messages: Belongs to the AccD/PCCB family.

1069220:G6N11 RS04090
gene id: 1069220:G6N11_RS04090
uniprot id: A0A7I7SAS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1069220:G6N11 RS00780
gene id: 1069220:G6N11_RS00780
uniprot id: A0A7I7S9M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1069220:G6N11 RS11415
gene id: 1069220:G6N11_RS11415
uniprot id: A0A7I7SEQ1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1069220:G6N11 RS05450
gene id: 1069220:G6N11_RS05450
uniprot id: A0A7I7SBH4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1069220:G6N11 RS02350
gene id: 1069220:G6N11_RS02350
uniprot id: A0A7I7S9N3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1069220:G6N11 RS20210
gene id: 1069220:G6N11_RS20210
uniprot id: A0A7I7SIK5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1069220:G6N11 RS08610
gene id: 1069220:G6N11_RS08610
uniprot id: A0A7I7SEE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1069220:G6N11 RS04790
gene id: 1069220:G6N11_RS04790
uniprot id: A0A7I7SA86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1069220:G6N11 RS11685
gene id: 1069220:G6N11_RS11685
uniprot id: A0A7I7SDR2
names: Similarity
messages: Belongs to the UPF0336 family.

1069220:G6N11 RS11540
gene id: 1069220:G6N11_RS11540
uniprot id: A0A7I7SDP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1069220:G6N11 RS05300
gene id: 1069220:G6N11_RS05300
uniprot id: A0A7I7SBE5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1069220:G6N11 RS05180
gene id: 1069220:G6N11_RS05180
uniprot id: A0A7I7SCD1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1069220:G6N11 RS01620
gene id: 1069220:G6N11_RS01620
uniprot id: A0A7I7SAP5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1069220:G6N11 RS00245
gene id: 1069220:G6N11_RS00245
uniprot id: A0A7I7S8G6
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1069220:G6N11 RS04490
gene id: 1069220:G6N11_RS04490
uniprot id: A0A7I7SA30
names: Similarity
messages: Belongs to the universal stress protein A family.

1069220:G6N11 RS17695
gene id: 1069220:G6N11_RS17695
uniprot id: A0A7I7SJX8
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

1069220:G6N11 RS04405
gene id: 1069220:G6N11_RS04405
uniprot id: A0A7I7SB68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1069220:G6N11 RS09680
gene id: 1069220:G6N11_RS09680
uniprot id: A0A7I7SDS4
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1069220:G6N11 RS01550
gene id: 1069220:G6N11_RS01550
uniprot id: A0A7I7S971
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1069220:G6N11 RS01735
gene id: 1069220:G6N11_RS01735
uniprot id: A0A7I7S8G9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS11545
gene id: 1069220:G6N11_RS11545
uniprot id: A0A7I7SGB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1069220:G6N11 RS11370
gene id: 1069220:G6N11_RS11370
uniprot id: A0A7I7SF02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1069220:G6N11 RS08615
gene id: 1069220:G6N11_RS08615
uniprot id: A0A7I7SC16
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1069220:G6N11 RS10745
gene id: 1069220:G6N11_RS10745
uniprot id: A0A7I7SD74
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1069220:G6N11 RS05065
gene id: 1069220:G6N11_RS05065
uniprot id: A0A7I7SAL0
names: Similarity
messages: Belongs to the peptidase C40 family.

1069220:G6N11 RS18560
gene id: 1069220:G6N11_RS18560
uniprot id: A0A7I7SI92
names: Similarity
messages: Belongs to the cytochrome P450 family.

1069220:G6N11 RS00465
gene id: 1069220:G6N11_RS00465
uniprot id: A0A7I7S817
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1069220:G6N11 RS11290
gene id: 1069220:G6N11_RS11290
uniprot id: A0A7I7SG55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1069220:G6N11 RS19630
gene id: 1069220:G6N11_RS19630
uniprot id: A0A7I7SKY6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1069220:G6N11 RS03310
gene id: 1069220:G6N11_RS03310
uniprot id: A0A7I7S951
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1069220:G6N11 RS00370
gene id: 1069220:G6N11_RS00370
uniprot id: A0A7I7S7G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1069220:G6N11 RS01910
gene id: 1069220:G6N11_RS01910
uniprot id: A0A7I7S8V6
names: Similarity
messages: Belongs to the thioesterase family.

1069220:G6N11 RS13665
gene id: 1069220:G6N11_RS13665
uniprot id: A0A7I7SFD1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1069220:G6N11 RS18555
gene id: 1069220:G6N11_RS18555
uniprot id: A0A7I7SHR3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1069220:G6N11 RS08005
gene id: 1069220:G6N11_RS08005
uniprot id: A0A7I7SED1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1069220:G6N11 RS11445
gene id: 1069220:G6N11_RS11445
uniprot id: A0A7I7SG98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1069220:G6N11 RS17560
gene id: 1069220:G6N11_RS17560
uniprot id: A0A7I7SHG0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1069220:G6N11 RS08685
gene id: 1069220:G6N11_RS08685
uniprot id: A0A7I7SDK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1069220:G6N11 RS10380
gene id: 1069220:G6N11_RS10380
uniprot id: A0A7I7SE59
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1069220:G6N11 RS02020
gene id: 1069220:G6N11_RS02020
uniprot id: A0A7I7SAY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1069220:G6N11 RS01220
gene id: 1069220:G6N11_RS01220
uniprot id: A0A7I7S9L2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS16555
gene id: 1069220:G6N11_RS16555
uniprot id: A0A7I7SGI9
names: Subcellular Location Annotation
messages: Membrane

1069220:G6N11 RS01975
gene id: 1069220:G6N11_RS01975
uniprot id: A0A7I7SAB9
names: Subcellular Location Annotation
messages: Membrane

1069220:G6N11 RS07745
gene id: 1069220:G6N11_RS07745
uniprot id: A0A7I7SBL7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1069220:G6N11 RS10195
gene id: 1069220:G6N11_RS10195
uniprot id: A0A7I7SDF7
names: Subcellular Location Annotation
messages: Membrane

1069220:G6N11 RS10925
gene id: 1069220:G6N11_RS10925
uniprot id: A0A7I7SDU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1069220:G6N11 RS02295
gene id: 1069220:G6N11_RS02295
uniprot id: A0A7I7SA92
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1069220:G6N11 RS02865
gene id: 1069220:G6N11_RS02865
uniprot id: A0A7I7SAD7
names: Similarity
messages: Belongs to the YggT family.

1069220:G6N11 RS14075
gene id: 1069220:G6N11_RS14075
uniprot id: A0A7I7SHY3
names: Similarity
messages: Belongs to the WXG100 family.

1069220:G6N11 RS04160
gene id: 1069220:G6N11_RS04160
uniprot id: A0A7I7S9L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1069220:G6N11 RS14170
gene id: 1069220:G6N11_RS14170
uniprot id: A0A7I7SHU5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS02255
gene id: 1069220:G6N11_RS02255
uniprot id: A0A7I7SA16
names: Similarity
messages: Belongs to the TPP enzyme family.

1069220:G6N11 RS04335
gene id: 1069220:G6N11_RS04335
uniprot id: A0A7I7S9Q4
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1069220:G6N11 RS03330
gene id: 1069220:G6N11_RS03330
uniprot id: A0A7I7SAL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1069220:G6N11 RS18845
gene id: 1069220:G6N11_RS18845
uniprot id: A0A7I7SKP2
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1069220:G6N11 RS01665
gene id: 1069220:G6N11_RS01665
uniprot id: A0A7I7S881
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1069220:G6N11 RS00705
gene id: 1069220:G6N11_RS00705
uniprot id: A0A7I7S8P9
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1069220:G6N11 RS09255
gene id: 1069220:G6N11_RS09255
uniprot id: A0A7I7SE50
names: Similarity
messages: Belongs to the CsoR family.

1069220:G6N11 RS18325
gene id: 1069220:G6N11_RS18325
uniprot id: A0A7I7SK87
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

1069220:G6N11 RS18670
gene id: 1069220:G6N11_RS18670
uniprot id: A0A7I7SKE8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1069220:G6N11 RS17855
gene id: 1069220:G6N11_RS17855
uniprot id: A0A7I7SK61
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1069220:G6N11 RS00790
gene id: 1069220:G6N11_RS00790
uniprot id: A0A7I7S7W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1069220:G6N11 RS15975
gene id: 1069220:G6N11_RS15975
uniprot id: A0A7I7SG73
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

1069220:G6N11 RS08470
gene id: 1069220:G6N11_RS08470
uniprot id: A0A7I7SCB5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1069220:G6N11 RS17660
gene id: 1069220:G6N11_RS17660
uniprot id: A0A7I7SHH8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS18465
gene id: 1069220:G6N11_RS18465
uniprot id: A0A7I7SI72
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1069220:G6N11 RS12450
gene id: 1069220:G6N11_RS12450
uniprot id: A0A7I7SGV2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1069220:G6N11 RS04955
gene id: 1069220:G6N11_RS04955
uniprot id: A0A7I7SBG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
messages: Heterodimer of an alpha and a beta chain.

1069220:G6N11 RS02160
gene id: 1069220:G6N11_RS02160
uniprot id: A0A7I7S8H9
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1069220:G6N11 RS10750
gene id: 1069220:G6N11_RS10750
uniprot id: A0A7I7SDJ9
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family.
messages: Homotetramer.

1069220:G6N11 RS04220
gene id: 1069220:G6N11_RS04220
uniprot id: A0A7I7SBT1
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1069220:G6N11 RS08790
gene id: 1069220:G6N11_RS08790
uniprot id: A0A7I7SC42
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1069220:G6N11 RS18750
gene id: 1069220:G6N11_RS18750
uniprot id: A0A7I7SJ79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1069220:G6N11 RS03890
gene id: 1069220:G6N11_RS03890
uniprot id: A0A7I7SAN6
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

1069220:G6N11 RS03300
gene id: 1069220:G6N11_RS03300
uniprot id: A0A7I7SBM8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1069220:G6N11 RS07860
gene id: 1069220:G6N11_RS07860
uniprot id: A0A7I7SDX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1069220:G6N11 RS15635
gene id: 1069220:G6N11_RS15635
uniprot id: A0A7I7SIW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1069220:G6N11 RS10255
gene id: 1069220:G6N11_RS10255
uniprot id: A0A7I7SFK3
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1069220:G6N11 RS13660
gene id: 1069220:G6N11_RS13660
uniprot id: A0A7I7SEV2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS07785
gene id: 1069220:G6N11_RS07785
uniprot id: A0A7I7SD39
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1069220:G6N11 RS02895
gene id: 1069220:G6N11_RS02895
uniprot id: A0A7I7S8X8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1069220:G6N11 RS05390
gene id: 1069220:G6N11_RS05390
uniprot id: A0A7I7SAJ7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1069220:G6N11 RS02630
gene id: 1069220:G6N11_RS02630
uniprot id: A0A7I7S8S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1069220:G6N11 RS03095
gene id: 1069220:G6N11_RS03095
uniprot id: A0A7I7SBJ4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS04735
gene id: 1069220:G6N11_RS04735
uniprot id: A0A7I7S9Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

1069220:G6N11 RS05710
gene id: 1069220:G6N11_RS05710
uniprot id: A0A7I7SAZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1069220:G6N11 RS04655
gene id: 1069220:G6N11_RS04655
uniprot id: A0A7I7SBB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1069220:G6N11 RS18575
gene id: 1069220:G6N11_RS18575
uniprot id: A0A7I7SKJ0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1069220:G6N11 RS05135
gene id: 1069220:G6N11_RS05135
uniprot id: A0A7I7SA66
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1069220:G6N11 RS08160
gene id: 1069220:G6N11_RS08160
uniprot id: A0A7I7SE29
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1069220:G6N11 RS03385
gene id: 1069220:G6N11_RS03385
uniprot id: A0A7I7S963
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1069220:G6N11 RS10105
gene id: 1069220:G6N11_RS10105
uniprot id: A0A7I7SFH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1069220:G6N11 RS10200
gene id: 1069220:G6N11_RS10200
uniprot id: A0A7I7SCW1
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1069220:G6N11 RS18630
gene id: 1069220:G6N11_RS18630
uniprot id: A0A7I7SHP4
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1069220:G6N11 RS18755
gene id: 1069220:G6N11_RS18755
uniprot id: A0A7I7SHU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1069220:G6N11 RS19950
gene id: 1069220:G6N11_RS19950
uniprot id: A0A1X2LLG0
names: Similarity
messages: Belongs to the WXG100 family.

1069220:G6N11 RS13870
gene id: 1069220:G6N11_RS13870
uniprot id: A0A7I7SF06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1069220:G6N11 RS16050
gene id: 1069220:G6N11_RS16050
uniprot id: A0A7I7SI78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1069220:G6N11 RS10615
gene id: 1069220:G6N11_RS10615
uniprot id: A0A7I7SE94
names: Similarity
messages: Belongs to the UPRTase family.

1069220:G6N11 RS04700
gene id: 1069220:G6N11_RS04700
uniprot id: A0A7I7SB36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Involved in both the histidine and tryptophan biosynthetic pathways.

1069220:G6N11 RS11195
gene id: 1069220:G6N11_RS11195
uniprot id: A0A7I7SDF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1069220:G6N11 RS16520
gene id: 1069220:G6N11_RS16520
uniprot id: A0A7I7SHL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 85 family.
messages: Cell membrane
messages: Membrane

1069220:G6N11 RS09220
gene id: 1069220:G6N11_RS09220
uniprot id: A0A7I7SCD7
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1069220:G6N11 RS10915
gene id: 1069220:G6N11_RS10915
uniprot id: A0A7I7SEQ6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1069220:G6N11 RS00700
gene id: 1069220:G6N11_RS00700
uniprot id: A0A7I7S990
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1069220:G6N11 RS00840
gene id: 1069220:G6N11_RS00840
uniprot id: A0A7I7S9N8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1069220:G6N11 RS10710
gene id: 1069220:G6N11_RS10710
uniprot id: A0A7I7SF60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

1069220:G6N11 RS04895
gene id: 1069220:G6N11_RS04895
uniprot id: A0A7I7SBP9
names: Similarity
messages: Belongs to the asparaginase 1 family.

1069220:G6N11 RS03600
gene id: 1069220:G6N11_RS03600
uniprot id: A0A7I7SBA1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS20395
gene id: 1069220:G6N11_RS20395
uniprot id: A0A7I7SIP5
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1069220:G6N11 RS07950
gene id: 1069220:G6N11_RS07950
uniprot id: A0A7I7SBN5
names: Similarity
messages: Belongs to the LppX/LprAFG lipoprotein family.

1069220:G6N11 RS05270
gene id: 1069220:G6N11_RS05270
uniprot id: A0A7I7SA78
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1069220:G6N11 RS01680
gene id: 1069220:G6N11_RS01680
uniprot id: A0A7I7S883
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1069220:G6N11 RS11350
gene id: 1069220:G6N11_RS11350
uniprot id: A0A7I7SDJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1069220:G6N11 RS00075
gene id: 1069220:G6N11_RS00075
uniprot id: A0A7I7S7T7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1069220:G6N11 RS09705
gene id: 1069220:G6N11_RS09705
uniprot id: A0A7I7SF37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1069220:G6N11 RS10410
gene id: 1069220:G6N11_RS10410
uniprot id: A0A7I7SFJ7
names: Similarity
messages: Belongs to the AccD/PCCB family.

1069220:G6N11 RS14590
gene id: 1069220:G6N11_RS14590
uniprot id: A0A7I7SGG7
names: Similarity
messages: Belongs to the CsoR family.

1069220:G6N11 RS20185
gene id: 1069220:G6N11_RS20185
uniprot id: A0A7I7SKI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1069220:G6N11 RS07810
gene id: 1069220:G6N11_RS07810
uniprot id: A0A7I7SDX1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1069220:G6N11 RS03005
gene id: 1069220:G6N11_RS03005
uniprot id: A0A7I7SAN3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS01670
gene id: 1069220:G6N11_RS01670
uniprot id: A0A7I7SAQ6
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1069220:G6N11 RS19580
gene id: 1069220:G6N11_RS19580
uniprot id: A0A7I7SKX5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1069220:G6N11 RS11455
gene id: 1069220:G6N11_RS11455
uniprot id: A0A7I7SE00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1069220:G6N11 RS05720
gene id: 1069220:G6N11_RS05720
uniprot id: A0A7I7SCZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1069220:G6N11 RS13100
gene id: 1069220:G6N11_RS13100
uniprot id: A0A7I7SH78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1069220:G6N11 RS11365
gene id: 1069220:G6N11_RS11365
uniprot id: A0A7I7SEN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1069220:G6N11 RS17605
gene id: 1069220:G6N11_RS17605
uniprot id: A0A7I7SH53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

1069220:G6N11 RS09050
gene id: 1069220:G6N11_RS09050
uniprot id: A0A7I7SCN3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1069220:G6N11 RS03710
gene id: 1069220:G6N11_RS03710
uniprot id: A0A7I7S9D3
names: Subcellular Location Annotation
messages: Membrane

1069220:G6N11 RS18035
gene id: 1069220:G6N11_RS18035
uniprot id: A0A7I7SHG1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1069220:G6N11 RS09960
gene id: 1069220:G6N11_RS09960
uniprot id: A0A7I7SF93
names: Similarity
messages: Belongs to the DEAD box helicase family.

1069220:G6N11 RS01555
gene id: 1069220:G6N11_RS01555
uniprot id: A0A7I7S9L6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1069220:G6N11 RS18615
gene id: 1069220:G6N11_RS18615
uniprot id: A0A7I7SHS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1069220:G6N11 RS20080
gene id: 1069220:G6N11_RS20080
uniprot id: A0A7I7SJ16
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family.
messages: Homotetramer.

1069220:G6N11 RS19830
gene id: 1069220:G6N11_RS19830
uniprot id: A0A7I7SKB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1069220:G6N11 RS04085
gene id: 1069220:G6N11_RS04085
uniprot id: A0A7I7SB84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1069220:G6N11 RS16000
gene id: 1069220:G6N11_RS16000
uniprot id: A0A7I7SG60
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1069220:G6N11 RS08835
gene id: 1069220:G6N11_RS08835
uniprot id: A0A7I7SCQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1069220:G6N11 RS01970
gene id: 1069220:G6N11_RS01970
uniprot id: A0A7I7SAX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1069220:G6N11 RS19595
gene id: 1069220:G6N11_RS19595
uniprot id: A0A7I7SIR5
names: Similarity
messages: Belongs to the peptidase S1C family.

1069220:G6N11 RS05760
gene id: 1069220:G6N11_RS05760
uniprot id: A0A7I7SB03
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1069220:G6N11 RS00420
gene id: 1069220:G6N11_RS00420
uniprot id: A0A7I7S7H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1069220:G6N11 RS03880
gene id: 1069220:G6N11_RS03880
uniprot id: A0A7I7S9R0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1069220:G6N11 RS05635
gene id: 1069220:G6N11_RS05635
uniprot id: A0A7I7SAP7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1069220:G6N11 RS01580
gene id: 1069220:G6N11_RS01580
uniprot id: A0A7I7S865
names: Similarity
messages: Belongs to the saccharopine dehydrogenase family. Enoyl reductase subfamily.

1069220:G6N11 RS01125
gene id: 1069220:G6N11_RS01125
uniprot id: A0A1X2LLG0
names: Similarity
messages: Belongs to the WXG100 family.

1069220:G6N11 RS14285
gene id: 1069220:G6N11_RS14285
uniprot id: A0A7I7SFL2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS07825
gene id: 1069220:G6N11_RS07825
uniprot id: A0A7I7SDE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1069220:G6N11 RS02935
gene id: 1069220:G6N11_RS02935
uniprot id: A0A7I7SBG7
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1069220:G6N11 RS15925
gene id: 1069220:G6N11_RS15925
uniprot id: A0A7I7SG61
names: Subcellular Location Annotation
messages: Membrane

1069220:G6N11 RS10890
gene id: 1069220:G6N11_RS10890
uniprot id: A0A7I7SFW8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1069220:G6N11 RS01815
gene id: 1069220:G6N11_RS01815
uniprot id: A0A7I7S8B4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1069220:G6N11 RS07865
gene id: 1069220:G6N11_RS07865
uniprot id: A0A7I7SBP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1069220:G6N11 RS05120
gene id: 1069220:G6N11_RS05120
uniprot id: A0A7I7SA47
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1069220:G6N11 RS10010
gene id: 1069220:G6N11_RS10010
uniprot id: A0A7I7SFA5
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

1069220:G6N11 RS02790
gene id: 1069220:G6N11_RS02790
uniprot id: A0A7I7SAT7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1069220:G6N11 RS13785
gene id: 1069220:G6N11_RS13785
uniprot id: A0A7I7SEX4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1069220:G6N11 RS12150
gene id: 1069220:G6N11_RS12150
uniprot id: A0A7I7SEH9
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1069220:G6N11 RS05695
gene id: 1069220:G6N11_RS05695
uniprot id: A0A7I7SBL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1069220:G6N11 RS01950
gene id: 1069220:G6N11_RS01950
uniprot id: A0A7I7S9V6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1069220:G6N11 RS05275
gene id: 1069220:G6N11_RS05275
uniprot id: A0A7I7SCQ7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1069220:G6N11 RS11615
gene id: 1069220:G6N11_RS11615
uniprot id: A0A7I7SFP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1069220:G6N11 RS18535
gene id: 1069220:G6N11_RS18535
uniprot id: A0A7I7SHM5
names: Similarity
messages: Belongs to the GARS family.

1069220:G6N11 RS16855
gene id: 1069220:G6N11_RS16855
uniprot id: A0A7I7SIP4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1069220:G6N11 RS11875
gene id: 1069220:G6N11_RS11875
uniprot id: A0A7I7SFV3
names: Similarity
messages: Belongs to the glutamate synthase family.

1069220:G6N11 RS08420
gene id: 1069220:G6N11_RS08420
uniprot id: A0A7I7SCA3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1069220:G6N11 RS11420
gene id: 1069220:G6N11_RS11420
uniprot id: A0A7I7SF15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1069220:G6N11 RS20075
gene id: 1069220:G6N11_RS20075
uniprot id: A0A7I7SIH5
names: Subcellular Location Annotation
messages: Membrane

1069220:G6N11 RS15445
gene id: 1069220:G6N11_RS15445
uniprot id: A0A7I7SG86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1069220:G6N11 RS17630
gene id: 1069220:G6N11_RS17630
uniprot id: A0A7I7SH84
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1069220:G6N11 RS10170
gene id: 1069220:G6N11_RS10170
uniprot id: A0A7I7SD97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1069220:G6N11 RS17690
gene id: 1069220:G6N11_RS17690
uniprot id: A0A7I7SH89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1069220:G6N11 RS20795
gene id: 1069220:G6N11_RS20795
uniprot id: A0A7I7SAH0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1069220:G6N11 RS08175
gene id: 1069220:G6N11_RS08175
uniprot id: A0A7I7SDK8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1069220:G6N11 RS14325
gene id: 1069220:G6N11_RS14325
uniprot id: A0A7I7SI33
names: Similarity
messages: Belongs to the mycobacterial PPE family.

1069220:G6N11 RS10360
gene id: 1069220:G6N11_RS10360
uniprot id: A0A7I7SFI7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1069220:G6N11 RS05360
gene id: 1069220:G6N11_RS05360
uniprot id: A0A7I7SAA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1069220:G6N11 RS02980
gene id: 1069220:G6N11_RS02980
uniprot id: A0A7I7S9H8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1069220:G6N11 RS00115
gene id: 1069220:G6N11_RS00115
uniprot id: A0A7I7S8P8
names: Similarity
messages: Belongs to the cytochrome P450 family.

1069220:G6N11 RS07615
gene id: 1069220:G6N11_RS07615
uniprot id: A0A7I7SDR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1069220:G6N11 RS09285
gene id: 1069220:G6N11_RS09285
uniprot id: A0A7I7SF25
names: Subcellular Location Annotation
messages: Membrane

1069220:G6N11 RS10810
gene id: 1069220:G6N11_RS10810
uniprot id: A0A7I7SEC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1069220:G6N11 RS03955
gene id: 1069220:G6N11_RS03955
uniprot id: A0A7I7SA01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1069220:G6N11 RS19860
gene id: 1069220:G6N11_RS19860
uniprot id: A0A7I7SL34
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1069220:G6N11 RS17700
gene id: 1069220:G6N11_RS17700
uniprot id: A0A7I7SK36
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

1069220:G6N11 RS10020
gene id: 1069220:G6N11_RS10020
uniprot id: A0A7I7SD70
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1069220:G6N11 RS01150
gene id: 1069220:G6N11_RS01150
uniprot id: A0A7I7SAE7
names: Similarity
messages: Belongs to the EccE family.

1069220:G6N11 RS04030
gene id: 1069220:G6N11_RS04030
uniprot id: A0A7I7S9U3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1069220:G6N11 RS17385
gene id: 1069220:G6N11_RS17385
uniprot id: A0A7I7SH26
names: Subcellular Location Annotation
messages: Cytoplasm

1069220:G6N11 RS07970
gene id: 1069220:G6N11_RS07970
uniprot id: A0A7I7SC17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1069220:G6N11 RS07780
gene id: 1069220:G6N11_RS07780
uniprot id: A0A7I7SCS6
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.

1069220:G6N11 RS10145
gene id: 1069220:G6N11_RS10145
uniprot id: A0A7I7SDE6
names: Similarity
messages: Belongs to the thymidylate kinase family.

1069220:G6N11 RS18250
gene id: 1069220:G6N11_RS18250
uniprot id: A0A7I7SJH7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1069220:G6N11 RS18590
gene id: 1069220:G6N11_RS18590
uniprot id: A0A7I7SJP0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1069220:G6N11 RS20605
gene id: 1069220:G6N11_RS20605
uniprot id: A0A7I7SHX8
names: Subcellular Location Annotation
messages: Cell membrane

1069220:G6N11 RS11355
gene id: 1069220:G6N11_RS11355
uniprot id: A0A7I7SDX7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1069220:G6N11 RS08505
gene id: 1069220:G6N11_RS08505
uniprot id: A0A7I7SEM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1069220:G6N11 RS03375
gene id: 1069220:G6N11_RS03375
uniprot id: A0A7I7SA81
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1069220:G6N11 RS07905
gene id: 1069220:G6N11_RS07905
uniprot id: A0A7I7SEB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1069220:G6N11 RS08535
gene id: 1069220:G6N11_RS08535
uniprot id: A0A7I7SDH6
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1069220:G6N11 RS07610
gene id: 1069220:G6N11_RS07610
uniprot id: A0A7I7SE64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1069220:G6N11 RS10720
gene id: 1069220:G6N11_RS10720
uniprot id: A0A7I7SEL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1069220:G6N11 RS05675
gene id: 1069220:G6N11_RS05675
uniprot id: A0A7I7SCN8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1069220:G6N11 RS04650
gene id: 1069220:G6N11_RS04650
uniprot id: A0A7I7SB27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1069220:G6N11 RS16440
gene id: 1069220:G6N11_RS16440
uniprot id: A0A7I7SGI3
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1069220:G6N11 RS03015
gene id: 1069220:G6N11_RS03015
uniprot id: A0A7I7SAG3
names: Similarity
messages: Belongs to the AccD/PCCB family.

1069220:G6N11 RS20355
gene id: 1069220:G6N11_RS20355
uniprot id: A0A7I7SLD1
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1069220:G6N11 RS05355
gene id: 1069220:G6N11_RS05355
uniprot id: A0A7I7SBP2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1069220:G6N11 RS20350
gene id: 1069220:G6N11_RS20350
uniprot id: A0A7I7SIN5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1069220:G6N11 RS18470
gene id: 1069220:G6N11_RS18470
uniprot id: A0A7I7SHP6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1069220:G6N11 RS13270
gene id: 1069220:G6N11_RS13270
uniprot id: A0A7I7SGN0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1069220:G6N11 RS04075
gene id: 1069220:G6N11_RS04075
uniprot id: A0A7I7S9K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1069220:G6N11 RS10210
gene id: 1069220:G6N11_RS10210
uniprot id: A0A7I7SFF5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1069220:G6N11 RS10795
gene id: 1069220:G6N11_RS10795
uniprot id: A0A7I7SD77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1069220:G6N11 RS10675
gene id: 1069220:G6N11_RS10675
uniprot id: A0A7I7SD63
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1069220:G6N11 RS13310
gene id: 1069220:G6N11_RS13310
uniprot id: A0A7I7SEM9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1069220:G6N11 RS14360
gene id: 1069220:G6N11_RS14360
uniprot id: A0A7I7SFR9
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily.
messages: Homodimer.

1069220:G6N11 RS03060
gene id: 1069220:G6N11_RS03060
uniprot id: A0A7I7SAP0
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1069220:G6N11 RS18870
gene id: 1069220:G6N11_RS18870
uniprot id: A0A7I7SJ96
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1069220:G6N11 RS00835
gene id: 1069220:G6N11_RS00835
uniprot id: A0A7I7SA91
names: Similarity
messages: Belongs to the TlyA family.

1069220:G6N11 RS11660
gene id: 1069220:G6N11_RS11660
uniprot id: A0A7I7SE42
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1069220:G6N11 RS05410
gene id: 1069220:G6N11_RS05410
uniprot id: A0A7I7SAA6
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1069220:G6N11 RS18075
gene id: 1069220:G6N11_RS18075
uniprot id: A0A7I7SHH2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS12425
gene id: 1069220:G6N11_RS12425
uniprot id: A0A7I7SFC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

1069220:G6N11 RS19720
gene id: 1069220:G6N11_RS19720
uniprot id: A0A7I7SL71
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1069220:G6N11 RS18980
gene id: 1069220:G6N11_RS18980
uniprot id: A0A7I7SIG2
names: Similarity
messages: Belongs to the MmpS family.

1069220:G6N11 RS00760
gene id: 1069220:G6N11_RS00760
uniprot id: A0A7I7S7P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1069220:G6N11 RS02405
gene id: 1069220:G6N11_RS02405
uniprot id: A0A7I7S9P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1069220:G6N11 RS04400
gene id: 1069220:G6N11_RS04400
uniprot id: A0A7I7SAY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1069220:G6N11 RS11190
gene id: 1069220:G6N11_RS11190
uniprot id: A0A7I7SG44
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1069220:G6N11 RS03400
gene id: 1069220:G6N11_RS03400
uniprot id: A0A7I7SBP6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1069220:G6N11 RS16165
gene id: 1069220:G6N11_RS16165
uniprot id: A0A7I7SGU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

1069220:G6N11 RS18765
gene id: 1069220:G6N11_RS18765
uniprot id: A0A7I7SHU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1069220:G6N11 RS03115
gene id: 1069220:G6N11_RS03115
uniprot id: A0A7I7SAP8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS00635
gene id: 1069220:G6N11_RS00635
uniprot id: A0A7I7S7M4
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

1069220:G6N11 RS04725
gene id: 1069220:G6N11_RS04725
uniprot id: A0A7I7SCE7
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1069220:G6N11 RS16395
gene id: 1069220:G6N11_RS16395
uniprot id: A0A7I7SGZ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1069220:G6N11 RS19800
gene id: 1069220:G6N11_RS19800
uniprot id: A0A7I7SIW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1069220:G6N11 RS18900
gene id: 1069220:G6N11_RS18900
uniprot id: A0A7I7SHU1
names: Subcellular Location Annotation
messages: Membrane

1069220:G6N11 RS18795
gene id: 1069220:G6N11_RS18795
uniprot id: A0A7I7SJ15
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

1069220:G6N11 RS08990
gene id: 1069220:G6N11_RS08990
uniprot id: A0A7I7SEW6
names: Function
names: Similarity
messages: Belongs to the MerB family.
messages: Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase.

1069220:G6N11 RS19555
gene id: 1069220:G6N11_RS19555
uniprot id: A0A7I7SJG2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS01450
gene id: 1069220:G6N11_RS01450
uniprot id: A0A7I7S838
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1069220:G6N11 RS00085
gene id: 1069220:G6N11_RS00085
uniprot id: A0A7I7S9U4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS02745
gene id: 1069220:G6N11_RS02745
uniprot id: A0A7I7S8V0
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1069220:G6N11 RS11280
gene id: 1069220:G6N11_RS11280
uniprot id: A0A7I7SE19
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1069220:G6N11 RS09095
gene id: 1069220:G6N11_RS09095
uniprot id: A0A7I7SCA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1069220:G6N11 RS15990
gene id: 1069220:G6N11_RS15990
uniprot id: A0A7I7SIV6
names: Similarity
messages: Belongs to the catalase family.

1069220:G6N11 RS00380
gene id: 1069220:G6N11_RS00380
uniprot id: A0A7I7S9D6
names: Subcellular Location Annotation
messages: Membrane

1069220:G6N11 RS10855
gene id: 1069220:G6N11_RS10855
uniprot id: A0A7I7SF89
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1069220:G6N11 RS03110
gene id: 1069220:G6N11_RS03110
uniprot id: A0A7I7S9B3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1069220:G6N11 RS13105
gene id: 1069220:G6N11_RS13105
uniprot id: A0A7I7SHE1
names: Similarity
messages: Belongs to the AAA ATPase family.

1069220:G6N11 RS16980
gene id: 1069220:G6N11_RS16980
uniprot id: A0A7I7SGT9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1069220:G6N11 RS16295
gene id: 1069220:G6N11_RS16295
uniprot id: A0A7I7SGX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1069220:G6N11 RS05800
gene id: 1069220:G6N11_RS05800
uniprot id: A0A7I7SBY8
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1069220:G6N11 RS07895
gene id: 1069220:G6N11_RS07895
uniprot id: A0A7I7SC73
names: Similarity
messages: Belongs to the PspA/IM30 family.

1069220:G6N11 RS09715
gene id: 1069220:G6N11_RS09715
uniprot id: A0A7I7SD10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1069220:G6N11 RS01705
gene id: 1069220:G6N11_RS01705
uniprot id: A0A7I7S890
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1069220:G6N11 RS11435
gene id: 1069220:G6N11_RS11435
uniprot id: A0A7I7SDM3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1069220:G6N11 RS13585
gene id: 1069220:G6N11_RS13585
uniprot id: A0A7I7SET8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1069220:G6N11 RS16570
gene id: 1069220:G6N11_RS16570
uniprot id: A0A7I7SHM6
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

1069220:G6N11 RS16290
gene id: 1069220:G6N11_RS16290
uniprot id: A0A7I7SGE9
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1069220:G6N11 RS04455
gene id: 1069220:G6N11_RS04455
uniprot id: A0A7I7SB77
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1069220:G6N11 RS10785
gene id: 1069220:G6N11_RS10785
uniprot id: A0A7I7SFW2
names: Subcellular Location Annotation
messages: Membrane

1069220:G6N11 RS11650
gene id: 1069220:G6N11_RS11650
uniprot id: A0A7I7SGE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1069220:G6N11 RS19135
gene id: 1069220:G6N11_RS19135
uniprot id: A0A7I7SI16
names: Similarity
messages: Belongs to the citrate synthase family.

1069220:G6N11 RS00495
gene id: 1069220:G6N11_RS00495
uniprot id: A0A7I7S949
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1069220:G6N11 RS01605
gene id: 1069220:G6N11_RS01605
uniprot id: A0A7I7S869
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1069220:G6N11 RS13715
gene id: 1069220:G6N11_RS13715
uniprot id: A0A7I7SFD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1069220:G6N11 RS00755
gene id: 1069220:G6N11_RS00755
uniprot id: A0A7I7S930
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1069220:G6N11 RS08445
gene id: 1069220:G6N11_RS08445
uniprot id: A0A7I7SCI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1069220:G6N11 RS17145
gene id: 1069220:G6N11_RS17145
uniprot id: A0A7I7SJR4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

1069220:G6N11 RS18780
gene id: 1069220:G6N11_RS18780
uniprot id: A0A7I7SHS2
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1069220:G6N11 RS18635
gene id: 1069220:G6N11_RS18635
uniprot id: A0A7I7SI17
names: Similarity
messages: Belongs to the peptidase M18 family.

1069220:G6N11 RS00330
gene id: 1069220:G6N11_RS00330
uniprot id: A0A7I7S7G8
names: Similarity
messages: Belongs to the LOG family.

1069220:G6N11 RS11655
gene id: 1069220:G6N11_RS11655
uniprot id: A0A7I7SDQ2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1069220:G6N11 RS16135
gene id: 1069220:G6N11_RS16135
uniprot id: A0A7I7SG91
names: Similarity
messages: Belongs to the WXG100 family.

1069220:G6N11 RS05185
gene id: 1069220:G6N11_RS05185
uniprot id: A0A7I7SA79
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1069220:G6N11 RS14305
gene id: 1069220:G6N11_RS14305
uniprot id: A0A7I7SF77
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1069220:G6N11 RS02345
gene id: 1069220:G6N11_RS02345
uniprot id: A0A7I7SAA3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1069220:G6N11 RS03865
gene id: 1069220:G6N11_RS03865
uniprot id: A0A7I7SBZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1069220:G6N11 RS16145
gene id: 1069220:G6N11_RS16145
uniprot id: A0A7I7SI98
names: Similarity
messages: Belongs to the mycobacterial PPE family.

1069220:G6N11 RS18260
gene id: 1069220:G6N11_RS18260
uniprot id: A0A7I7SIZ1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS02150
gene id: 1069220:G6N11_RS02150
uniprot id: A0A7I7S9J3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1069220:G6N11 RS17235
gene id: 1069220:G6N11_RS17235
uniprot id: A0A7I7SJM5
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme modulates the balance between respiration and glycolysis, and contributes to redox homeostasis. Probably eliminates toxic levels of Cys (which can induce oxidative stress).
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

1069220:G6N11 RS16955
gene id: 1069220:G6N11_RS16955
uniprot id: A0A7I7SGS0
names: Similarity
messages: Belongs to the CFA/CMAS family.

1069220:G6N11 RS05400
gene id: 1069220:G6N11_RS05400
uniprot id: A0A7I7SBG2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1069220:G6N11 RS18675
gene id: 1069220:G6N11_RS18675
uniprot id: A0A7I7SKL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1069220:G6N11 RS20220
gene id: 1069220:G6N11_RS20220
uniprot id: A0A7I7SLH7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1069220:G6N11 RS07630
gene id: 1069220:G6N11_RS07630
uniprot id: A0A7I7SDA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1069220:G6N11 RS07685
gene id: 1069220:G6N11_RS07685
uniprot id: A0A7I7SCQ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1069220:G6N11 RS08440
gene id: 1069220:G6N11_RS08440
uniprot id: A0A7I7SBY5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1069220:G6N11 RS01250
gene id: 1069220:G6N11_RS01250
uniprot id: A0A7I7SAG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1069220:G6N11 RS17595
gene id: 1069220:G6N11_RS17595
uniprot id: A0A7I7SJW0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

1069220:G6N11 RS13725
gene id: 1069220:G6N11_RS13725
uniprot id: A0A7I7SHK8
names: Subcellular Location Annotation
messages: Membrane

1069220:G6N11 RS10820
gene id: 1069220:G6N11_RS10820
uniprot id: A0A7I7SD90
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1069220:G6N11 RS10875
gene id: 1069220:G6N11_RS10875
uniprot id: A0A7I7SDT6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1069220:G6N11 RS04865
gene id: 1069220:G6N11_RS04865
uniprot id: A0A7I7SAG8
names: Subcellular Location Annotation
messages: Cytoplasm

1069220:G6N11 RS17635
gene id: 1069220:G6N11_RS17635
uniprot id: A0A7I7SHQ7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1069220:G6N11 RS11345
gene id: 1069220:G6N11_RS11345
uniprot id: A0A7I7SG76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1069220:G6N11 RS11360
gene id: 1069220:G6N11_RS11360
uniprot id: A0A7I7SFJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1069220:G6N11 RS00630
gene id: 1069220:G6N11_RS00630
uniprot id: A0A7I7S9J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1069220:G6N11 RS18245
gene id: 1069220:G6N11_RS18245
uniprot id: A0A7I7SHU4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1069220:G6N11 RS17640
gene id: 1069220:G6N11_RS17640
uniprot id: A0A7I7SH80
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1069220:G6N11 RS09090
gene id: 1069220:G6N11_RS09090
uniprot id: A0A7I7SEQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1069220:G6N11 RS11595
gene id: 1069220:G6N11_RS11595
uniprot id: A0A7I7SGC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1069220:G6N11 RS16660
gene id: 1069220:G6N11_RS16660
uniprot id: A0A7I7SIK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

1069220:G6N11 RS17240
gene id: 1069220:G6N11_RS17240
uniprot id: A0A7I7SJT4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1069220:G6N11 RS14870
gene id: 1069220:G6N11_RS14870
uniprot id: A0A7I7SFI3
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

1069220:G6N11 RS20305
gene id: 1069220:G6N11_RS20305
uniprot id: A0A7I7SIM5
names: Similarity
messages: Belongs to the citrate synthase family.

1069220:G6N11 RS16540
gene id: 1069220:G6N11_RS16540
uniprot id: A0A7I7SGK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1069220:G6N11 RS18015
gene id: 1069220:G6N11_RS18015
uniprot id: A0A7I7SIM3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1069220:G6N11 RS17740
gene id: 1069220:G6N11_RS17740
uniprot id: A0A7I7SH99
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS12240
gene id: 1069220:G6N11_RS12240
uniprot id: A0A7I7SE26
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1069220:G6N11 RS01615
gene id: 1069220:G6N11_RS01615
uniprot id: A0A7I7S871
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1069220:G6N11 RS00725
gene id: 1069220:G6N11_RS00725
uniprot id: A0A7I7S7N4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1069220:G6N11 RS11675
gene id: 1069220:G6N11_RS11675
uniprot id: A0A7I7SEV7
names: Similarity
messages: Belongs to the UPF0336 family.

1069220:G6N11 RS01675
gene id: 1069220:G6N11_RS01675
uniprot id: A0A7I7SA63
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1069220:G6N11 RS08600
gene id: 1069220:G6N11_RS08600
uniprot id: A0A7I7SC04
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1069220:G6N11 RS19810
gene id: 1069220:G6N11_RS19810
uniprot id: A0A7I7SL24
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1069220:G6N11 RS05125
gene id: 1069220:G6N11_RS05125
uniprot id: A0A7I7SCM6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1069220:G6N11 RS02585
gene id: 1069220:G6N11_RS02585
uniprot id: A0A7I7SBB2
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1069220:G6N11 RS11640
gene id: 1069220:G6N11_RS11640
uniprot id: A0A7I7SDR3
names: Similarity
messages: Belongs to the CFA/CMAS family.

1069220:G6N11 RS01140
gene id: 1069220:G6N11_RS01140
uniprot id: A0A7I7S8G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccD/Snm4 family.
messages: Membrane

1069220:G6N11 RS12140
gene id: 1069220:G6N11_RS12140
uniprot id: A0A7I7SFH1
names: Similarity
messages: Belongs to the UPF0234 family.

1069220:G6N11 RS05575
gene id: 1069220:G6N11_RS05575
uniprot id: A0A1X2LLG0
names: Similarity
messages: Belongs to the WXG100 family.

1069220:G6N11 RS01960
gene id: 1069220:G6N11_RS01960
uniprot id: A0A7I7S8W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1069220:G6N11 RS02460
gene id: 1069220:G6N11_RS02460
uniprot id: A0A7I7S9Q1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1069220:G6N11 RS05660
gene id: 1069220:G6N11_RS05660
uniprot id: A0A7I7SAY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1069220:G6N11 RS04690
gene id: 1069220:G6N11_RS04690
uniprot id: A0A7I7SA69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1069220:G6N11 RS20385
gene id: 1069220:G6N11_RS20385
uniprot id: A0A7I7SIS1
names: Subcellular Location Annotation
messages: Membrane

1069220:G6N11 RS08145
gene id: 1069220:G6N11_RS08145
uniprot id: A0A7I7SCC4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1069220:G6N11 RS03705
gene id: 1069220:G6N11_RS03705
uniprot id: A0A7I7SAK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1069220:G6N11 RS04710
gene id: 1069220:G6N11_RS04710
uniprot id: A0A7I7S9X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1069220:G6N11 RS10135
gene id: 1069220:G6N11_RS10135
uniprot id: A0A7I7SEA8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1069220:G6N11 RS05380
gene id: 1069220:G6N11_RS05380
uniprot id: A0A7I7SCH3
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1069220:G6N11 RS11330
gene id: 1069220:G6N11_RS11330
uniprot id: A0A7I7SE31
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1069220:G6N11 RS09660
gene id: 1069220:G6N11_RS09660
uniprot id: A0A7I7SF28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1069220:G6N11 RS04625
gene id: 1069220:G6N11_RS04625
uniprot id: A0A7I7S9V7
names: Subcellular Location Annotation
messages: Membrane

1069220:G6N11 RS05385
gene id: 1069220:G6N11_RS05385
uniprot id: A0A7I7SAB7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1069220:G6N11 RS01545
gene id: 1069220:G6N11_RS01545
uniprot id: A0A7I7S9T0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1069220:G6N11 RS05685
gene id: 1069220:G6N11_RS05685
uniprot id: A0A7I7SAQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1069220:G6N11 RS18230
gene id: 1069220:G6N11_RS18230
uniprot id: A0A7I7SK71
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1069220:G6N11 RS04120
gene id: 1069220:G6N11_RS04120
uniprot id: A0A7I7S9K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1069220:G6N11 RS07750
gene id: 1069220:G6N11_RS07750
uniprot id: A0A7I7SC47
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1069220:G6N11 RS13780
gene id: 1069220:G6N11_RS13780
uniprot id: A0A7I7SHS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1069220:G6N11 RS00460
gene id: 1069220:G6N11_RS00460
uniprot id: A0A7I7S7I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1069220:G6N11 RS08030
gene id: 1069220:G6N11_RS08030
uniprot id: A0A7I7SCW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1069220:G6N11 RS11410
gene id: 1069220:G6N11_RS11410
uniprot id: A0A7I7SFK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1069220:G6N11 RS19260
gene id: 1069220:G6N11_RS19260
uniprot id: A0A7I7SFI7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1069220:G6N11 RS16035
gene id: 1069220:G6N11_RS16035
uniprot id: A0A7I7SIW6
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1069220:G6N11 RS11890
gene id: 1069220:G6N11_RS11890
uniprot id: A0A7I7SDV4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1069220:G6N11 RS14065
gene id: 1069220:G6N11_RS14065
uniprot id: A0A7I7SF46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccD/Snm4 family.
messages: Membrane

1069220:G6N11 RS18625
gene id: 1069220:G6N11_RS18625
uniprot id: A0A7I7SKK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

1069220:G6N11 RS00340
gene id: 1069220:G6N11_RS00340
uniprot id: A0A7I7S918
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1069220:G6N11 RS14275
gene id: 1069220:G6N11_RS14275
uniprot id: A0A7I7SI21
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1069220:G6N11 RS02525
gene id: 1069220:G6N11_RS02525
uniprot id: A0A7I7S994
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1069220:G6N11 RS20315
gene id: 1069220:G6N11_RS20315
uniprot id: A0A7I7SLJ7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS05315
gene id: 1069220:G6N11_RS05315
uniprot id: A0A7I7SAR4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1069220:G6N11 RS05365
gene id: 1069220:G6N11_RS05365
uniprot id: A0A7I7SAS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1069220:G6N11 RS04070
gene id: 1069220:G6N11_RS04070
uniprot id: A0A7I7SBJ3
names: Similarity
messages: Belongs to the UPF0749 family.

1069220:G6N11 RS08000
gene id: 1069220:G6N11_RS08000
uniprot id: A0A7I7SBP7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1069220:G6N11 RS01330
gene id: 1069220:G6N11_RS01330
uniprot id: A0A7I7S9N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1069220:G6N11 RS11530
gene id: 1069220:G6N11_RS11530
uniprot id: A0A7I7SDN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1069220:G6N11 RS17550
gene id: 1069220:G6N11_RS17550
uniprot id: A0A7I7SK05
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1069220:G6N11 RS17730
gene id: 1069220:G6N11_RS17730
uniprot id: A0A7I7SHA3
names: Similarity
messages: Belongs to the peptidase C59 family.

1069220:G6N11 RS15690
gene id: 1069220:G6N11_RS15690
uniprot id: A0A7I7SIP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1069220:G6N11 RS20085
gene id: 1069220:G6N11_RS20085
uniprot id: A0A7I7SKG6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1069220:G6N11 RS11205
gene id: 1069220:G6N11_RS11205
uniprot id: A0A7I7SFG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1069220:G6N11 RS03630
gene id: 1069220:G6N11_RS03630
uniprot id: A0A7I7S9T9
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

1069220:G6N11 RS10435
gene id: 1069220:G6N11_RS10435
uniprot id: A0A7I7SEG1
names: Similarity
messages: Belongs to the SufE family.

1069220:G6N11 RS01730
gene id: 1069220:G6N11_RS01730
uniprot id: A0A7I7S898
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS08620
gene id: 1069220:G6N11_RS08620
uniprot id: A0A7I7SCE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1069220:G6N11 RS09600
gene id: 1069220:G6N11_RS09600
uniprot id: A0A7I7SCJ7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1069220:G6N11 RS09215
gene id: 1069220:G6N11_RS09215
uniprot id: A0A7I7SDW5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1069220:G6N11 RS00770
gene id: 1069220:G6N11_RS00770
uniprot id: A0A7I7S7P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: In the C-terminal section; belongs to the ATPase delta chain family.
messages: In the N-terminal section; belongs to the ATPase B chain family.
messages: Membrane
messages: This fusion protein includes a component of the F(0) channel (subunit b) and of the F(1) subunit (subunit delta). Two copies of subunit b and one of delta together form the peripheral 'stator' stalk which links F(1) to F(0).
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1069220:G6N11 RS00730
gene id: 1069220:G6N11_RS00730
uniprot id: A0A7I7SA75
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1069220:G6N11 RS02510
gene id: 1069220:G6N11_RS02510
uniprot id: A0A7I7S9S1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1069220:G6N11 RS10830
gene id: 1069220:G6N11_RS10830
uniprot id: A0A7I7SD99
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1069220:G6N11 RS14165
gene id: 1069220:G6N11_RS14165
uniprot id: A0A7I7SF68
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1069220:G6N11 RS09410
gene id: 1069220:G6N11_RS09410
uniprot id: A0A7I7SCH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1069220:G6N11 RS13750
gene id: 1069220:G6N11_RS13750
uniprot id: A0A7I7SG14
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

1069220:G6N11 RS21205
gene id: 1069220:G6N11_RS21205
uniprot id: A0A7I7SIG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1069220:G6N11 RS11690
gene id: 1069220:G6N11_RS11690
uniprot id: A0A7I7SE96
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1069220:G6N11 RS09670
gene id: 1069220:G6N11_RS09670
uniprot id: A0A7I7SD01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1069220:G6N11 RS04950
gene id: 1069220:G6N11_RS04950
uniprot id: A0A7I7SB81
names: Function
names: Subunit
messages: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
messages: Heterodimer of an alpha and a beta chain.