106370:FRANCCI3 RS02525
gene id: 106370:FRANCCI3_RS02525
uniprot id: Q2JFQ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

106370:FRANCCI3 RS18095
gene id: 106370:FRANCCI3_RS18095
uniprot id: Q2J705
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

106370:FRANCCI3 RS04695
gene id: 106370:FRANCCI3_RS04695
uniprot id: Q2JEH0
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

106370:FRANCCI3 RS07450
gene id: 106370:FRANCCI3_RS07450
uniprot id: Q2JCY4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

106370:FRANCCI3 RS12475
gene id: 106370:FRANCCI3_RS12475
uniprot id: Q2JA42
names: Similarity
messages: Belongs to the CapA family.

106370:FRANCCI3 RS22815
gene id: 106370:FRANCCI3_RS22815
uniprot id: A0A1X1PU23
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS18790
gene id: 106370:FRANCCI3_RS18790
uniprot id: Q2J6M0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

106370:FRANCCI3 RS16135
gene id: 106370:FRANCCI3_RS16135
uniprot id: A0A1X1PTS7
uniprot id: Q2J829
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS14420
gene id: 106370:FRANCCI3_RS14420
uniprot id: Q2J914
names: Similarity
messages: Belongs to the CFA/CMAS family.

106370:FRANCCI3 RS22845
gene id: 106370:FRANCCI3_RS22845
uniprot id: Q2J4D1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

106370:FRANCCI3 RS03450
gene id: 106370:FRANCCI3_RS03450
uniprot id: Q2JF72
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS20985
gene id: 106370:FRANCCI3_RS20985
uniprot id: Q2J5E0
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS03570
gene id: 106370:FRANCCI3_RS03570
uniprot id: Q2JF49
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

106370:FRANCCI3 RS03845
gene id: 106370:FRANCCI3_RS03845
uniprot id: Q2JEZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

106370:FRANCCI3 RS06640
gene id: 106370:FRANCCI3_RS06640
uniprot id: A0A1X1PYH5
uniprot id: Q2JDD9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS06550
gene id: 106370:FRANCCI3_RS06550
uniprot id: Q2JDF7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

106370:FRANCCI3 RS11515
gene id: 106370:FRANCCI3_RS11515
uniprot id: A0A1X1PZ00
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS08420
gene id: 106370:FRANCCI3_RS08420
uniprot id: Q2JCE0
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS17705
gene id: 106370:FRANCCI3_RS17705
uniprot id: Q2J781
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

106370:FRANCCI3 RS15155
gene id: 106370:FRANCCI3_RS15155
uniprot id: Q2J8M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

106370:FRANCCI3 RS06570
gene id: 106370:FRANCCI3_RS06570
uniprot id: Q2JDF3
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

106370:FRANCCI3 RS02150
gene id: 106370:FRANCCI3_RS02150
uniprot id: Q2JFX6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

106370:FRANCCI3 RS20490
gene id: 106370:FRANCCI3_RS20490
uniprot id: Q2J5N6
names: Similarity
messages: Belongs to the IucA/IucC family.

106370:FRANCCI3 RS11065
gene id: 106370:FRANCCI3_RS11065
uniprot id: Q2JAX0
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

106370:FRANCCI3 RS04015
gene id: 106370:FRANCCI3_RS04015
uniprot id: Q2JEV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

106370:FRANCCI3 RS04205
gene id: 106370:FRANCCI3_RS04205
uniprot id: A0A1X1PYD1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS07160
gene id: 106370:FRANCCI3_RS07160
uniprot id: Q2JD41
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

106370:FRANCCI3 RS12340
gene id: 106370:FRANCCI3_RS12340
uniprot id: Q2JA70
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

106370:FRANCCI3 RS15510
gene id: 106370:FRANCCI3_RS15510
uniprot id: Q2J8E9
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

106370:FRANCCI3 RS03745
gene id: 106370:FRANCCI3_RS03745
uniprot id: Q2JF13
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

106370:FRANCCI3 RS16455
gene id: 106370:FRANCCI3_RS16455
uniprot id: Q2J7W2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

106370:FRANCCI3 RS01530
gene id: 106370:FRANCCI3_RS01530
uniprot id: Q2JG98
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

106370:FRANCCI3 RS07070
gene id: 106370:FRANCCI3_RS07070
uniprot id: A0A1X1Q0M4
uniprot id: Q2JD59
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleoid

106370:FRANCCI3 RS10405
gene id: 106370:FRANCCI3_RS10405
uniprot id: Q2JBA2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

106370:FRANCCI3 RS15050
gene id: 106370:FRANCCI3_RS15050
uniprot id: Q2J8P2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

106370:FRANCCI3 RS14165
gene id: 106370:FRANCCI3_RS14165
uniprot id: Q2J967
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

106370:FRANCCI3 RS15165
gene id: 106370:FRANCCI3_RS15165
uniprot id: Q2J8L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

106370:FRANCCI3 RS22105
gene id: 106370:FRANCCI3_RS22105
uniprot id: Q2J4S8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

106370:FRANCCI3 RS18625
gene id: 106370:FRANCCI3_RS18625
uniprot id: Q2J6Q3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

106370:FRANCCI3 RS14430
gene id: 106370:FRANCCI3_RS14430
uniprot id: Q2J912
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

106370:FRANCCI3 RS08260
gene id: 106370:FRANCCI3_RS08260
uniprot id: Q2JCH2
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS11370
gene id: 106370:FRANCCI3_RS11370
uniprot id: Q2JAR0
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

106370:FRANCCI3 RS01215
gene id: 106370:FRANCCI3_RS01215
uniprot id: Q2JGG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

106370:FRANCCI3 RS06905
gene id: 106370:FRANCCI3_RS06905
uniprot id: Q2JD90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

106370:FRANCCI3 RS09605
gene id: 106370:FRANCCI3_RS09605
uniprot id: Q2JBQ4
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS02670
gene id: 106370:FRANCCI3_RS02670
uniprot id: A0A1X1PUP1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS00990
gene id: 106370:FRANCCI3_RS00990
uniprot id: Q2JGK7
names: Similarity
messages: Belongs to the HsdR family.

106370:FRANCCI3 RS19810
gene id: 106370:FRANCCI3_RS19810
uniprot id: Q2J616
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

106370:FRANCCI3 RS11255
gene id: 106370:FRANCCI3_RS11255
uniprot id: Q2JAT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

106370:FRANCCI3 RS09255
gene id: 106370:FRANCCI3_RS09255
uniprot id: Q2JBX8
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

106370:FRANCCI3 RS10800
gene id: 106370:FRANCCI3_RS10800
uniprot id: A0A1X1PV78
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS00515
gene id: 106370:FRANCCI3_RS00515
uniprot id: A0A1X1PWY0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS02560
gene id: 106370:FRANCCI3_RS02560
uniprot id: Q2JFP4
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS22680
gene id: 106370:FRANCCI3_RS22680
uniprot id: Q2J4G3
names: Similarity
messages: Belongs to the NifX/NifY family.

106370:FRANCCI3 RS03090
gene id: 106370:FRANCCI3_RS03090
uniprot id: Q2JFE2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

106370:FRANCCI3 RS03775
gene id: 106370:FRANCCI3_RS03775
uniprot id: A0A1X1Q2Z0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS13035
gene id: 106370:FRANCCI3_RS13035
uniprot id: Q2J9U4
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS13120
gene id: 106370:FRANCCI3_RS13120
uniprot id: Q2J9S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

106370:FRANCCI3 RS19690
gene id: 106370:FRANCCI3_RS19690
uniprot id: A0A1X1PUD8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS02955
gene id: 106370:FRANCCI3_RS02955
uniprot id: Q2JFH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

106370:FRANCCI3 RS15140
gene id: 106370:FRANCCI3_RS15140
uniprot id: Q2J8M4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

106370:FRANCCI3 RS09695
gene id: 106370:FRANCCI3_RS09695
uniprot id: Q2JBN7
names: Similarity
messages: Belongs to the cytochrome P450 family.

106370:FRANCCI3 RS11785
gene id: 106370:FRANCCI3_RS11785
uniprot id: Q2JAH8
names: Similarity
messages: Belongs to the transposase 7 family.

106370:FRANCCI3 RS15970
gene id: 106370:FRANCCI3_RS15970
uniprot id: Q2J861
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

106370:FRANCCI3 RS20510
gene id: 106370:FRANCCI3_RS20510
uniprot id: Q2J5N2
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS04690
gene id: 106370:FRANCCI3_RS04690
uniprot id: Q2JEH1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

106370:FRANCCI3 RS14290
gene id: 106370:FRANCCI3_RS14290
uniprot id: Q2J941
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

106370:FRANCCI3 RS17455
gene id: 106370:FRANCCI3_RS17455
uniprot id: Q2J7D0
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

106370:FRANCCI3 RS19590
gene id: 106370:FRANCCI3_RS19590
uniprot id: A0A1X1PTA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS15640
gene id: 106370:FRANCCI3_RS15640
uniprot id: Q2J8C3
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

106370:FRANCCI3 RS07570
gene id: 106370:FRANCCI3_RS07570
uniprot id: A0A1X1Q0F2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS04025
gene id: 106370:FRANCCI3_RS04025
uniprot id: Q2JEV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

106370:FRANCCI3 RS18270
gene id: 106370:FRANCCI3_RS18270
uniprot id: Q2J6X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

106370:FRANCCI3 RS02735
gene id: 106370:FRANCCI3_RS02735
uniprot id: A0A1X1PUP7
uniprot id: Q2JFL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS19310
gene id: 106370:FRANCCI3_RS19310
uniprot id: Q2J6C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

106370:FRANCCI3 RS02985
gene id: 106370:FRANCCI3_RS02985
uniprot id: Q2JFG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

106370:FRANCCI3 RS03050
gene id: 106370:FRANCCI3_RS03050
uniprot id: Q2JFF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

106370:FRANCCI3 RS11655
gene id: 106370:FRANCCI3_RS11655
uniprot id: Q2JAK3
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS18405
gene id: 106370:FRANCCI3_RS18405
uniprot id: Q2J6U5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

106370:FRANCCI3 RS01525
gene id: 106370:FRANCCI3_RS01525
uniprot id: Q2JG99
names: Similarity
messages: Belongs to the thymidylate kinase family.

106370:FRANCCI3 RS09140
gene id: 106370:FRANCCI3_RS09140
uniprot id: Q2JC01
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

106370:FRANCCI3 RS15725
gene id: 106370:FRANCCI3_RS15725
uniprot id: Q2J8A6
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

106370:FRANCCI3 RS04185
gene id: 106370:FRANCCI3_RS04185
uniprot id: Q2JES6
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

106370:FRANCCI3 RS11375
gene id: 106370:FRANCCI3_RS11375
uniprot id: A0A1X1PYX4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS22085
gene id: 106370:FRANCCI3_RS22085
uniprot id: Q2J4T2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

106370:FRANCCI3 RS18355
gene id: 106370:FRANCCI3_RS18355
uniprot id: Q2J6V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

106370:FRANCCI3 RS01400
gene id: 106370:FRANCCI3_RS01400
uniprot id: Q2JGC6
names: Similarity
messages: Belongs to the group II decarboxylase family.

106370:FRANCCI3 RS15125
gene id: 106370:FRANCCI3_RS15125
uniprot id: Q2J8M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

106370:FRANCCI3 RS17925
gene id: 106370:FRANCCI3_RS17925
uniprot id: Q2J739
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

106370:FRANCCI3 RS10520
gene id: 106370:FRANCCI3_RS10520
uniprot id: Q2JB80
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

106370:FRANCCI3 RS18825
gene id: 106370:FRANCCI3_RS18825
uniprot id: Q2J6L3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

106370:FRANCCI3 RS23595
gene id: 106370:FRANCCI3_RS23595
uniprot id: A0A1X1PX31
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS06035
gene id: 106370:FRANCCI3_RS06035
uniprot id: Q2JDR0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

106370:FRANCCI3 RS13875
gene id: 106370:FRANCCI3_RS13875
uniprot id: Q2J9C5
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS15500
gene id: 106370:FRANCCI3_RS15500
uniprot id: Q2J8F1
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

106370:FRANCCI3 RS18295
gene id: 106370:FRANCCI3_RS18295
uniprot id: A0A1X1PXP9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS13390
gene id: 106370:FRANCCI3_RS13390
uniprot id: Q2J9M4
names: Similarity
messages: Belongs to the PrpD family.

106370:FRANCCI3 RS04235
gene id: 106370:FRANCCI3_RS04235
uniprot id: A0A1X1PYC6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS04035
gene id: 106370:FRANCCI3_RS04035
uniprot id: Q2JEV5
names: Similarity
messages: Belongs to the HIBADH-related family.

106370:FRANCCI3 RS12355
gene id: 106370:FRANCCI3_RS12355
uniprot id: Q2JA67
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

106370:FRANCCI3 RS17790
gene id: 106370:FRANCCI3_RS17790
uniprot id: Q2J764
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

106370:FRANCCI3 RS12540
gene id: 106370:FRANCCI3_RS12540
uniprot id: Q2JA28
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

106370:FRANCCI3 RS19795
gene id: 106370:FRANCCI3_RS19795
uniprot id: Q2J619
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

106370:FRANCCI3 RS19350
gene id: 106370:FRANCCI3_RS19350
uniprot id: Q2J6B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

106370:FRANCCI3 RS16515
gene id: 106370:FRANCCI3_RS16515
uniprot id: Q2J7V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

106370:FRANCCI3 RS04335
gene id: 106370:FRANCCI3_RS04335
uniprot id: A0A1X1PTS8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS16505
gene id: 106370:FRANCCI3_RS16505
uniprot id: Q2J7V2
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS04370
gene id: 106370:FRANCCI3_RS04370
uniprot id: A0A1X1PTS6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS00300
gene id: 106370:FRANCCI3_RS00300
uniprot id: Q2JGY7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

106370:FRANCCI3 RS01885
gene id: 106370:FRANCCI3_RS01885
uniprot id: Q2JG24
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS03115
gene id: 106370:FRANCCI3_RS03115
uniprot id: Q2JFD7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

106370:FRANCCI3 RS22155
gene id: 106370:FRANCCI3_RS22155
uniprot id: Q2J4R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

106370:FRANCCI3 RS08035
gene id: 106370:FRANCCI3_RS08035
uniprot id: A0A1X1Q1X5
names: Caution
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS18425
gene id: 106370:FRANCCI3_RS18425
uniprot id: Q2J6U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

106370:FRANCCI3 RS03120
gene id: 106370:FRANCCI3_RS03120
uniprot id: Q2JFD6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

106370:FRANCCI3 RS07880
gene id: 106370:FRANCCI3_RS07880
uniprot id: Q2JCP8
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS27865
gene id: 106370:FRANCCI3_RS27865
uniprot id: A0A1X1Q0R5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS08360
gene id: 106370:FRANCCI3_RS08360
uniprot id: Q2JCF2
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

106370:FRANCCI3 RS05745
gene id: 106370:FRANCCI3_RS05745
uniprot id: Q2JDW4
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

106370:FRANCCI3 RS18130
gene id: 106370:FRANCCI3_RS18130
uniprot id: A0A1X1PSH7
uniprot id: Q2J6Z8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS06065
gene id: 106370:FRANCCI3_RS06065
uniprot id: Q2JDQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

106370:FRANCCI3 RS12220
gene id: 106370:FRANCCI3_RS12220
uniprot id: Q2JA95
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

106370:FRANCCI3 RS12530
gene id: 106370:FRANCCI3_RS12530
uniprot id: Q2JA30
names: Similarity
messages: Belongs to the TPP enzyme family.

106370:FRANCCI3 RS17960
gene id: 106370:FRANCCI3_RS17960
uniprot id: Q2J733
names: Similarity
messages: Belongs to the ribF family.

106370:FRANCCI3 RS22410
gene id: 106370:FRANCCI3_RS22410
uniprot id: Q2J4L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

106370:FRANCCI3 RS14815
gene id: 106370:FRANCCI3_RS14815
uniprot id: Q2J8T7
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

106370:FRANCCI3 RS13810
gene id: 106370:FRANCCI3_RS13810
uniprot id: Q2J9D7
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS21695
gene id: 106370:FRANCCI3_RS21695
uniprot id: Q2J504
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS15610
gene id: 106370:FRANCCI3_RS15610
uniprot id: Q2J8C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

106370:FRANCCI3 RS16520
gene id: 106370:FRANCCI3_RS16520
uniprot id: Q2J7U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

106370:FRANCCI3 RS05960
gene id: 106370:FRANCCI3_RS05960
uniprot id: A0A1X1PUR2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS06225
gene id: 106370:FRANCCI3_RS06225
uniprot id: Q2JDM3
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

106370:FRANCCI3 RS18335
gene id: 106370:FRANCCI3_RS18335
uniprot id: Q2J6V9
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

106370:FRANCCI3 RS22560
gene id: 106370:FRANCCI3_RS22560
uniprot id: Q2J4I9
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

106370:FRANCCI3 RS03445
gene id: 106370:FRANCCI3_RS03445
uniprot id: Q2JF73
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

106370:FRANCCI3 RS04385
gene id: 106370:FRANCCI3_RS04385
uniprot id: Q2JEN4
names: Similarity
messages: Belongs to the HIBADH-related family.

106370:FRANCCI3 RS10885
gene id: 106370:FRANCCI3_RS10885
uniprot id: Q2JB05
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

106370:FRANCCI3 RS02970
gene id: 106370:FRANCCI3_RS02970
uniprot id: Q2JFG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

106370:FRANCCI3 RS19510
gene id: 106370:FRANCCI3_RS19510
uniprot id: A0A1X1PSD5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS09950
gene id: 106370:FRANCCI3_RS09950
uniprot id: A0A1X1Q0D1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS21445
gene id: 106370:FRANCCI3_RS21445
uniprot id: Q2J555
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

106370:FRANCCI3 RS13275
gene id: 106370:FRANCCI3_RS13275
uniprot id: Q2J9P5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

106370:FRANCCI3 RS10915
gene id: 106370:FRANCCI3_RS10915
uniprot id: Q2JAZ9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

106370:FRANCCI3 RS21570
gene id: 106370:FRANCCI3_RS21570
uniprot id: Q2J529
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

106370:FRANCCI3 RS16465
gene id: 106370:FRANCCI3_RS16465
uniprot id: Q2J7W0
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

106370:FRANCCI3 RS18505
gene id: 106370:FRANCCI3_RS18505
uniprot id: Q2J6S8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

106370:FRANCCI3 RS18705
gene id: 106370:FRANCCI3_RS18705
uniprot id: Q2J6N6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

106370:FRANCCI3 RS02445
gene id: 106370:FRANCCI3_RS02445
uniprot id: Q2JFR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

106370:FRANCCI3 RS13420
gene id: 106370:FRANCCI3_RS13420
uniprot id: A0A1X1PVQ9
uniprot id: Q2J9L8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS21465
gene id: 106370:FRANCCI3_RS21465
uniprot id: Q2J551
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

106370:FRANCCI3 RS24935
gene id: 106370:FRANCCI3_RS24935
uniprot id: A0A1X1PXQ1
uniprot id: Q2J6Y2
names: Caution
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS19955
gene id: 106370:FRANCCI3_RS19955
uniprot id: A0A1X1PZT2
names: Caution
names: Similarity
messages: Belongs to the asp23 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS15760
gene id: 106370:FRANCCI3_RS15760
uniprot id: Q2J8A0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

106370:FRANCCI3 RS02195
gene id: 106370:FRANCCI3_RS02195
uniprot id: A0A1X1PQL8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS19975
gene id: 106370:FRANCCI3_RS19975
uniprot id: Q2J5Y5
names: Similarity
messages: Belongs to the asp23 family.

106370:FRANCCI3 RS01300
gene id: 106370:FRANCCI3_RS01300
uniprot id: Q2JGE4
names: Subcellular Location Annotation
messages: Cytoplasm

106370:FRANCCI3 RS13360
gene id: 106370:FRANCCI3_RS13360
uniprot id: Q2J9N0
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS25195
gene id: 106370:FRANCCI3_RS25195
uniprot id: A0A1X1PVB7
uniprot id: Q2J498
names: Caution
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS20365
gene id: 106370:FRANCCI3_RS20365
uniprot id: A0A1X1PRW4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

106370:FRANCCI3 RS11720
gene id: 106370:FRANCCI3_RS11720
uniprot id: Q2JAI9
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

106370:FRANCCI3 RS06275
gene id: 106370:FRANCCI3_RS06275
uniprot id: A0A1X1Q0T6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS18650
gene id: 106370:FRANCCI3_RS18650
uniprot id: Q2J6P7
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS07410
gene id: 106370:FRANCCI3_RS07410
uniprot id: Q2JCZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

106370:FRANCCI3 RS07155
gene id: 106370:FRANCCI3_RS07155
uniprot id: Q2JD42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

106370:FRANCCI3 RS02095
gene id: 106370:FRANCCI3_RS02095
uniprot id: Q2JFY5
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

106370:FRANCCI3 RS26620
gene id: 106370:FRANCCI3_RS26620
uniprot id: A0A1X1PUJ7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS04045
gene id: 106370:FRANCCI3_RS04045
uniprot id: A0A1X1PVA4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS10895
gene id: 106370:FRANCCI3_RS10895
uniprot id: Q2JB03
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

106370:FRANCCI3 RS16150
gene id: 106370:FRANCCI3_RS16150
uniprot id: Q2J826
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

106370:FRANCCI3 RS15710
gene id: 106370:FRANCCI3_RS15710
uniprot id: Q2J8A9
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

106370:FRANCCI3 RS16075
gene id: 106370:FRANCCI3_RS16075
uniprot id: Q2J841
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

106370:FRANCCI3 RS19230
gene id: 106370:FRANCCI3_RS19230
uniprot id: A0A1X1PRN8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS22590
gene id: 106370:FRANCCI3_RS22590
uniprot id: Q2J4I2
names: Similarity
messages: Belongs to the cytochrome P450 family.

106370:FRANCCI3 RS13395
gene id: 106370:FRANCCI3_RS13395
uniprot id: Q2J9M3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

106370:FRANCCI3 RS03045
gene id: 106370:FRANCCI3_RS03045
uniprot id: Q2JFF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

106370:FRANCCI3 RS21820
gene id: 106370:FRANCCI3_RS21820
uniprot id: Q2J4Y2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS22345
gene id: 106370:FRANCCI3_RS22345
uniprot id: Q2J4M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

106370:FRANCCI3 RS05335
gene id: 106370:FRANCCI3_RS05335
uniprot id: Q2JE45
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

106370:FRANCCI3 RS02860
gene id: 106370:FRANCCI3_RS02860
uniprot id: Q2JFI9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

106370:FRANCCI3 RS11995
gene id: 106370:FRANCCI3_RS11995
uniprot id: Q2JAD8
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS11225
gene id: 106370:FRANCCI3_RS11225
uniprot id: Q2JAT9
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS16050
gene id: 106370:FRANCCI3_RS16050
uniprot id: Q2J846
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

106370:FRANCCI3 RS14810
gene id: 106370:FRANCCI3_RS14810
uniprot id: Q2J8T8
names: Similarity
messages: Belongs to the AlaDH/PNT family.

106370:FRANCCI3 RS08375
gene id: 106370:FRANCCI3_RS08375
uniprot id: Q2JCE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

106370:FRANCCI3 RS11895
gene id: 106370:FRANCCI3_RS11895
uniprot id: Q2JAF8
names: Similarity
messages: Belongs to the transposase 7 family.

106370:FRANCCI3 RS18770
gene id: 106370:FRANCCI3_RS18770
uniprot id: Q2J6M4
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS13565
gene id: 106370:FRANCCI3_RS13565
uniprot id: Q2J9I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

106370:FRANCCI3 RS19215
gene id: 106370:FRANCCI3_RS19215
uniprot id: A0A1X1PSZ3
names: Caution
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS03330
gene id: 106370:FRANCCI3_RS03330
uniprot id: Q2JF95
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS15845
gene id: 106370:FRANCCI3_RS15845
uniprot id: A0A1X1PX66
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS01125
gene id: 106370:FRANCCI3_RS01125
uniprot id: Q2JGI0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

106370:FRANCCI3 RS18745
gene id: 106370:FRANCCI3_RS18745
uniprot id: Q2J6M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

106370:FRANCCI3 RS14015
gene id: 106370:FRANCCI3_RS14015
uniprot id: A0A1X1PU69
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS17975
gene id: 106370:FRANCCI3_RS17975
uniprot id: A0A1X1PU97
uniprot id: Q2J730
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS02700
gene id: 106370:FRANCCI3_RS02700
uniprot id: Q2JFL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

106370:FRANCCI3 RS03300
gene id: 106370:FRANCCI3_RS03300
uniprot id: Q2JFA1
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

106370:FRANCCI3 RS07355
gene id: 106370:FRANCCI3_RS07355
uniprot id: Q2JD03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

106370:FRANCCI3 RS14225
gene id: 106370:FRANCCI3_RS14225
uniprot id: Q2J954
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

106370:FRANCCI3 RS06900
gene id: 106370:FRANCCI3_RS06900
uniprot id: Q2JD91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

106370:FRANCCI3 RS07095
gene id: 106370:FRANCCI3_RS07095
uniprot id: Q2JD54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

106370:FRANCCI3 RS09715
gene id: 106370:FRANCCI3_RS09715
uniprot id: A0A1X1PXR0
names: Caution
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS17445
gene id: 106370:FRANCCI3_RS17445
uniprot id: Q2J7D2
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS13240
gene id: 106370:FRANCCI3_RS13240
uniprot id: Q2J9Q2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

106370:FRANCCI3 RS15690
gene id: 106370:FRANCCI3_RS15690
uniprot id: Q2J8B3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

106370:FRANCCI3 RS17280
gene id: 106370:FRANCCI3_RS17280
uniprot id: Q2J7G5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

106370:FRANCCI3 RS16140
gene id: 106370:FRANCCI3_RS16140
uniprot id: Q2J828
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS11395
gene id: 106370:FRANCCI3_RS11395
uniprot id: Q2JAQ6
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

106370:FRANCCI3 RS04010
gene id: 106370:FRANCCI3_RS04010
uniprot id: Q2JEW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

106370:FRANCCI3 RS17680
gene id: 106370:FRANCCI3_RS17680
uniprot id: Q2J786
names: Similarity
messages: Belongs to the histone deacetylase family.

106370:FRANCCI3 RS22515
gene id: 106370:FRANCCI3_RS22515
uniprot id: Q2J4J7
names: Similarity
messages: Belongs to the universal stress protein A family.

106370:FRANCCI3 RS19600
gene id: 106370:FRANCCI3_RS19600
uniprot id: Q2J660
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

106370:FRANCCI3 RS06375
gene id: 106370:FRANCCI3_RS06375
uniprot id: Q2JDJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

106370:FRANCCI3 RS07735
gene id: 106370:FRANCCI3_RS07735
uniprot id: Q2JCS7
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

106370:FRANCCI3 RS19920
gene id: 106370:FRANCCI3_RS19920
uniprot id: A0A1X1Q0I2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS17955
gene id: 106370:FRANCCI3_RS17955
uniprot id: A0A1X1PUB1
uniprot id: Q2J734
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS16175
gene id: 106370:FRANCCI3_RS16175
uniprot id: Q2J821
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

106370:FRANCCI3 RS20485
gene id: 106370:FRANCCI3_RS20485
uniprot id: Q2J5N7
names: Similarity
messages: Belongs to the group II decarboxylase family.

106370:FRANCCI3 RS18600
gene id: 106370:FRANCCI3_RS18600
uniprot id: Q2J6Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

106370:FRANCCI3 RS00730
gene id: 106370:FRANCCI3_RS00730
uniprot id: Q2JGQ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106370:FRANCCI3 RS03765
gene id: 106370:FRANCCI3_RS03765
uniprot id: Q2JF10
names: Cofactor
messages: Binds 1 zinc ion per subunit.

106370:FRANCCI3 RS05405
gene id: 106370:FRANCCI3_RS05405
uniprot id: Q2JE31
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

106370:FRANCCI3 RS00535
gene id: 106370:FRANCCI3_RS00535
uniprot id: Q2JGU0
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

106370:FRANCCI3 RS20755
gene id: 106370:FRANCCI3_RS20755
uniprot id: Q2J5I6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

106370:FRANCCI3 RS15775
gene id: 106370:FRANCCI3_RS15775
uniprot id: A0A1X1PWJ1
uniprot id: Q2J897
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS06235
gene id: 106370:FRANCCI3_RS06235
uniprot id: Q2JDM1
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

106370:FRANCCI3 RS22865
gene id: 106370:FRANCCI3_RS22865
uniprot id: A0A1X1PRP8
uniprot id: Q2J4C7
names: Caution
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS20655
gene id: 106370:FRANCCI3_RS20655
uniprot id: Q2J5K5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

106370:FRANCCI3 RS02160
gene id: 106370:FRANCCI3_RS02160
uniprot id: A0A1X1PV00
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS03465
gene id: 106370:FRANCCI3_RS03465
uniprot id: Q2JF69
names: Similarity
messages: Belongs to the UPRTase family.

106370:FRANCCI3 RS22370
gene id: 106370:FRANCCI3_RS22370
uniprot id: Q2J4M4
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

106370:FRANCCI3 RS04175
gene id: 106370:FRANCCI3_RS04175
uniprot id: A0A1X1PYB5
uniprot id: Q2JES8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

106370:FRANCCI3 RS06260
gene id: 106370:FRANCCI3_RS06260
uniprot id: Q2JDL5
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS02965
gene id: 106370:FRANCCI3_RS02965
uniprot id: Q2JFG8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

106370:FRANCCI3 RS03180
gene id: 106370:FRANCCI3_RS03180
uniprot id: Q2JFC4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

106370:FRANCCI3 RS16550
gene id: 106370:FRANCCI3_RS16550
uniprot id: Q2J7U3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

106370:FRANCCI3 RS07330
gene id: 106370:FRANCCI3_RS07330
uniprot id: Q2JD07
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

106370:FRANCCI3 RS02435
gene id: 106370:FRANCCI3_RS02435
uniprot id: Q2JFR8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

106370:FRANCCI3 RS01250
gene id: 106370:FRANCCI3_RS01250
uniprot id: Q2JGF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

106370:FRANCCI3 RS03060
gene id: 106370:FRANCCI3_RS03060
uniprot id: Q2JFE8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

106370:FRANCCI3 RS14800
gene id: 106370:FRANCCI3_RS14800
uniprot id: Q2J8U0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

106370:FRANCCI3 RS28210
gene id: 106370:FRANCCI3_RS28210
uniprot id: A0A1X1PUB2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS20005
gene id: 106370:FRANCCI3_RS20005
uniprot id: Q2J5Y0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS00465
gene id: 106370:FRANCCI3_RS00465
uniprot id: Q2JGV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

106370:FRANCCI3 RS22000
gene id: 106370:FRANCCI3_RS22000
uniprot id: Q2J4U9
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

106370:FRANCCI3 RS15085
gene id: 106370:FRANCCI3_RS15085
uniprot id: Q2J8N5
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS27230
gene id: 106370:FRANCCI3_RS27230
uniprot id: A0A1X1PYV0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS15220
gene id: 106370:FRANCCI3_RS15220
uniprot id: Q2J8K8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

106370:FRANCCI3 RS07885
gene id: 106370:FRANCCI3_RS07885
uniprot id: Q2JCP7
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS03095
gene id: 106370:FRANCCI3_RS03095
uniprot id: Q2JFE1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

106370:FRANCCI3 RS22685
gene id: 106370:FRANCCI3_RS22685
uniprot id: Q2J4G2
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

106370:FRANCCI3 RS00215
gene id: 106370:FRANCCI3_RS00215
uniprot id: Q2JH03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

106370:FRANCCI3 RS03025
gene id: 106370:FRANCCI3_RS03025
uniprot id: Q2JFF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

106370:FRANCCI3 RS22340
gene id: 106370:FRANCCI3_RS22340
uniprot id: A0A1X1PWG8
uniprot id: Q2J4N0
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS16035
gene id: 106370:FRANCCI3_RS16035
uniprot id: Q2J849
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

106370:FRANCCI3 RS13310
gene id: 106370:FRANCCI3_RS13310
uniprot id: Q2J9N8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

106370:FRANCCI3 RS04755
gene id: 106370:FRANCCI3_RS04755
uniprot id: Q2JEF7
names: Similarity
messages: Belongs to the peptidase C56 family.

106370:FRANCCI3 RS18880
gene id: 106370:FRANCCI3_RS18880
uniprot id: A0A1X1PY64
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS18955
gene id: 106370:FRANCCI3_RS18955
uniprot id: Q2J6I9
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

106370:FRANCCI3 RS20080
gene id: 106370:FRANCCI3_RS20080
uniprot id: Q2J5W6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

106370:FRANCCI3 RS19700
gene id: 106370:FRANCCI3_RS19700
uniprot id: Q2J638
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

106370:FRANCCI3 RS16860
gene id: 106370:FRANCCI3_RS16860
uniprot id: Q2J7P0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

106370:FRANCCI3 RS12920
gene id: 106370:FRANCCI3_RS12920
uniprot id: A0A1X1PSW8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS10065
gene id: 106370:FRANCCI3_RS10065
uniprot id: Q2JBG4
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS02120
gene id: 106370:FRANCCI3_RS02120
uniprot id: A0A1X1PV09
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS22705
gene id: 106370:FRANCCI3_RS22705
uniprot id: Q2J4F8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg-99 inactivates the nitrogenase reductase and regulates nitrogenase activity.

106370:FRANCCI3 RS17490
gene id: 106370:FRANCCI3_RS17490
uniprot id: Q2J7C4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

106370:FRANCCI3 RS15425
gene id: 106370:FRANCCI3_RS15425
uniprot id: Q2J8G6
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS02400
gene id: 106370:FRANCCI3_RS02400
uniprot id: Q2JFS5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

106370:FRANCCI3 RS12375
gene id: 106370:FRANCCI3_RS12375
uniprot id: Q2JA63
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS07145
gene id: 106370:FRANCCI3_RS07145
uniprot id: Q2JD44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

106370:FRANCCI3 RS06630
gene id: 106370:FRANCCI3_RS06630
uniprot id: Q2JDE1
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS22030
gene id: 106370:FRANCCI3_RS22030
uniprot id: Q2J4U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

106370:FRANCCI3 RS06350
gene id: 106370:FRANCCI3_RS06350
uniprot id: Q2JDJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

106370:FRANCCI3 RS03085
gene id: 106370:FRANCCI3_RS03085
uniprot id: Q2JFE3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

106370:FRANCCI3 RS07455
gene id: 106370:FRANCCI3_RS07455
uniprot id: A0A1X1Q0K2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS13230
gene id: 106370:FRANCCI3_RS13230
uniprot id: Q2J9Q4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

106370:FRANCCI3 RS13960
gene id: 106370:FRANCCI3_RS13960
uniprot id: Q2J9A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

106370:FRANCCI3 RS03710
gene id: 106370:FRANCCI3_RS03710
uniprot id: Q2JF20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

106370:FRANCCI3 RS00710
gene id: 106370:FRANCCI3_RS00710
uniprot id: Q2JGQ6
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

106370:FRANCCI3 RS12625
gene id: 106370:FRANCCI3_RS12625
uniprot id: Q2JA11
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

106370:FRANCCI3 RS18990
gene id: 106370:FRANCCI3_RS18990
uniprot id: Q2J6I2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

106370:FRANCCI3 RS16525
gene id: 106370:FRANCCI3_RS16525
uniprot id: Q2J7U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

106370:FRANCCI3 RS17600
gene id: 106370:FRANCCI3_RS17600
uniprot id: Q2J7A2
names: Similarity
messages: Belongs to the AAA ATPase family.

106370:FRANCCI3 RS06400
gene id: 106370:FRANCCI3_RS06400
uniprot id: Q2JDI8
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

106370:FRANCCI3 RS28000
gene id: 106370:FRANCCI3_RS28000
uniprot id: Q2JB30
names: Similarity
messages: Belongs to the universal stress protein A family.

106370:FRANCCI3 RS03785
gene id: 106370:FRANCCI3_RS03785
uniprot id: Q2JF06
names: Similarity
messages: Belongs to the UPF0434 family.

106370:FRANCCI3 RS03110
gene id: 106370:FRANCCI3_RS03110
uniprot id: A0A1X1Q1F1
uniprot id: Q2JFD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

106370:FRANCCI3 RS17950
gene id: 106370:FRANCCI3_RS17950
uniprot id: Q2J735
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

106370:FRANCCI3 RS09785
gene id: 106370:FRANCCI3_RS09785
uniprot id: Q2JBM0
names: Similarity
messages: Belongs to the HypD family.

106370:FRANCCI3 RS22135
gene id: 106370:FRANCCI3_RS22135
uniprot id: Q2J4S3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

106370:FRANCCI3 RS18150
gene id: 106370:FRANCCI3_RS18150
uniprot id: Q2J6Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

106370:FRANCCI3 RS14630
gene id: 106370:FRANCCI3_RS14630
uniprot id: Q2J8X4
names: Similarity
messages: Belongs to the asparagine synthetase family.

106370:FRANCCI3 RS09550
gene id: 106370:FRANCCI3_RS09550
uniprot id: A0A1X1PUM1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS22035
gene id: 106370:FRANCCI3_RS22035
uniprot id: Q2J4U2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

106370:FRANCCI3 RS16265
gene id: 106370:FRANCCI3_RS16265
uniprot id: Q2J803
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS06980
gene id: 106370:FRANCCI3_RS06980
uniprot id: Q2JD76
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

106370:FRANCCI3 RS18485
gene id: 106370:FRANCCI3_RS18485
uniprot id: Q2J6T2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

106370:FRANCCI3 RS06965
gene id: 106370:FRANCCI3_RS06965
uniprot id: Q2JD78
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

106370:FRANCCI3 RS02755
gene id: 106370:FRANCCI3_RS02755
uniprot id: Q2JFK6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

106370:FRANCCI3 RS20760
gene id: 106370:FRANCCI3_RS20760
uniprot id: Q2J5I5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

106370:FRANCCI3 RS05385
gene id: 106370:FRANCCI3_RS05385
uniprot id: Q2JE35
names: Similarity
messages: Belongs to the peptidase A31 family.

106370:FRANCCI3 RS15810
gene id: 106370:FRANCCI3_RS15810
uniprot id: Q2J890
names: Similarity
messages: Belongs to the glutamine synthetase family.

106370:FRANCCI3 RS06170
gene id: 106370:FRANCCI3_RS06170
uniprot id: Q2JDN3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

106370:FRANCCI3 RS22295
gene id: 106370:FRANCCI3_RS22295
uniprot id: Q2J4N9
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

106370:FRANCCI3 RS00345
gene id: 106370:FRANCCI3_RS00345
uniprot id: Q2JGX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

106370:FRANCCI3 RS19525
gene id: 106370:FRANCCI3_RS19525
uniprot id: Q2J675
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

106370:FRANCCI3 RS18100
gene id: 106370:FRANCCI3_RS18100
uniprot id: Q2J704
names: Similarity
messages: Belongs to the UPF0102 family.

106370:FRANCCI3 RS14805
gene id: 106370:FRANCCI3_RS14805
uniprot id: Q2J8T9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

106370:FRANCCI3 RS15070
gene id: 106370:FRANCCI3_RS15070
uniprot id: Q2J8N8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

106370:FRANCCI3 RS02710
gene id: 106370:FRANCCI3_RS02710
uniprot id: Q2JFL5
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

106370:FRANCCI3 RS17120
gene id: 106370:FRANCCI3_RS17120
uniprot id: A0A1X1Q132
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS26285
gene id: 106370:FRANCCI3_RS26285
uniprot id: Q2J920
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

106370:FRANCCI3 RS15080
gene id: 106370:FRANCCI3_RS15080
uniprot id: Q2J8N6
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS01225
gene id: 106370:FRANCCI3_RS01225
uniprot id: Q2JGF9
names: Similarity
messages: Belongs to the YciI family.

106370:FRANCCI3 RS02865
gene id: 106370:FRANCCI3_RS02865
uniprot id: Q2JFI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

106370:FRANCCI3 RS03425
gene id: 106370:FRANCCI3_RS03425
uniprot id: Q2JF77
names: Cofactor
names: Similarity
messages: Belongs to the cytochrome b560 family.
messages: The heme is bound between the two transmembrane subunits.

106370:FRANCCI3 RS05325
gene id: 106370:FRANCCI3_RS05325
uniprot id: Q2JE47
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

106370:FRANCCI3 RS22130
gene id: 106370:FRANCCI3_RS22130
uniprot id: Q2J4S4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

106370:FRANCCI3 RS03490
gene id: 106370:FRANCCI3_RS03490
uniprot id: Q2JF65
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

106370:FRANCCI3 RS10920
gene id: 106370:FRANCCI3_RS10920
uniprot id: Q2JAZ8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

106370:FRANCCI3 RS22740
gene id: 106370:FRANCCI3_RS22740
uniprot id: Q2J4F0
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

106370:FRANCCI3 RS17885
gene id: 106370:FRANCCI3_RS17885
uniprot id: Q2J746
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

106370:FRANCCI3 RS00160
gene id: 106370:FRANCCI3_RS00160
uniprot id: Q2JH15
names: Similarity
messages: Belongs to the UPF0098 family.

106370:FRANCCI3 RS00200
gene id: 106370:FRANCCI3_RS00200
uniprot id: Q2JH07
names: Similarity
messages: Belongs to the peptidase C40 family.

106370:FRANCCI3 RS02420
gene id: 106370:FRANCCI3_RS02420
uniprot id: Q2JFS1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

106370:FRANCCI3 RS12570
gene id: 106370:FRANCCI3_RS12570
uniprot id: Q2JA22
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

106370:FRANCCI3 RS01245
gene id: 106370:FRANCCI3_RS01245
uniprot id: Q2JGF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
messages: Cell membrane
messages: Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (SsuB), two transmembrane proteins (SsuC) and a solute-binding protein (SsuA).

106370:FRANCCI3 RS07100
gene id: 106370:FRANCCI3_RS07100
uniprot id: Q2JD53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane

106370:FRANCCI3 RS18115
gene id: 106370:FRANCCI3_RS18115
uniprot id: Q2J701
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

106370:FRANCCI3 RS16545
gene id: 106370:FRANCCI3_RS16545
uniprot id: A0A1X1PWZ9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS02885
gene id: 106370:FRANCCI3_RS02885
uniprot id: Q2JFI4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

106370:FRANCCI3 RS11435
gene id: 106370:FRANCCI3_RS11435
uniprot id: A0A1X1PZ16
names: Caution
names: Similarity
messages: Belongs to the fatty acyl-CoA reductase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS04710
gene id: 106370:FRANCCI3_RS04710
uniprot id: Q2JEG7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

106370:FRANCCI3 RS16945
gene id: 106370:FRANCCI3_RS16945
uniprot id: Q2J7M4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

106370:FRANCCI3 RS17160
gene id: 106370:FRANCCI3_RS17160
uniprot id: Q2J7I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EfeM/EfeO family.
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

106370:FRANCCI3 RS01270
gene id: 106370:FRANCCI3_RS01270
uniprot id: Q2JGF0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

106370:FRANCCI3 RS11190
gene id: 106370:FRANCCI3_RS11190
uniprot id: Q2JAU6
names: Similarity
messages: Belongs to the PspA/IM30 family.

106370:FRANCCI3 RS14875
gene id: 106370:FRANCCI3_RS14875
uniprot id: A0A1X1PTZ8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS02825
gene id: 106370:FRANCCI3_RS02825
uniprot id: Q2JFJ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

106370:FRANCCI3 RS09205
gene id: 106370:FRANCCI3_RS09205
uniprot id: Q2JBY8
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

106370:FRANCCI3 RS03780
gene id: 106370:FRANCCI3_RS03780
uniprot id: Q2JF07
names: Similarity
messages: Belongs to the phosphohexose mutase family.

106370:FRANCCI3 RS08910
gene id: 106370:FRANCCI3_RS08910
uniprot id: Q2JC48
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS05390
gene id: 106370:FRANCCI3_RS05390
uniprot id: Q2JE34
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

106370:FRANCCI3 RS20000
gene id: 106370:FRANCCI3_RS20000
uniprot id: Q2J5Y1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

106370:FRANCCI3 RS11145
gene id: 106370:FRANCCI3_RS11145
uniprot id: A0A1X1PW67
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS04375
gene id: 106370:FRANCCI3_RS04375
uniprot id: Q2JEN6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

106370:FRANCCI3 RS17505
gene id: 106370:FRANCCI3_RS17505
uniprot id: Q2J7C1
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

106370:FRANCCI3 RS01340
gene id: 106370:FRANCCI3_RS01340
uniprot id: Q2JGD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

106370:FRANCCI3 RS15360
gene id: 106370:FRANCCI3_RS15360
uniprot id: Q2J8H9
names: Similarity
messages: Belongs to the UPF0047 family.

106370:FRANCCI3 RS23515
gene id: 106370:FRANCCI3_RS23515
uniprot id: A0A1X1PY58
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS13010
gene id: 106370:FRANCCI3_RS13010
uniprot id: Q2J9U9
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

106370:FRANCCI3 RS02595
gene id: 106370:FRANCCI3_RS02595
uniprot id: A0A1X1PQJ7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS19325
gene id: 106370:FRANCCI3_RS19325
uniprot id: Q2J6B8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

106370:FRANCCI3 RS17225
gene id: 106370:FRANCCI3_RS17225
uniprot id: A0A1X1Q0Y5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS16145
gene id: 106370:FRANCCI3_RS16145
uniprot id: Q2J827
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

106370:FRANCCI3 RS19005
gene id: 106370:FRANCCI3_RS19005
uniprot id: A0A1X1PRP5
uniprot id: Q2J6H9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS02925
gene id: 106370:FRANCCI3_RS02925
uniprot id: Q2JFH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

106370:FRANCCI3 RS06770
gene id: 106370:FRANCCI3_RS06770
uniprot id: Q2JDB3
names: Similarity
messages: Belongs to the band 7/mec-2 family.

106370:FRANCCI3 RS12620
gene id: 106370:FRANCCI3_RS12620
uniprot id: Q2JA12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

106370:FRANCCI3 RS21400
gene id: 106370:FRANCCI3_RS21400
uniprot id: Q2J565
names: Similarity
messages: Belongs to the terpene synthase family.

106370:FRANCCI3 RS07310
gene id: 106370:FRANCCI3_RS07310
uniprot id: Q2JD11
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

106370:FRANCCI3 RS08210
gene id: 106370:FRANCCI3_RS08210
uniprot id: Q2JCI2
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

106370:FRANCCI3 RS08030
gene id: 106370:FRANCCI3_RS08030
uniprot id: Q2JCL7
names: Similarity
messages: Belongs to the cytochrome P450 family.

106370:FRANCCI3 RS11540
gene id: 106370:FRANCCI3_RS11540
uniprot id: Q2JAM7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

106370:FRANCCI3 RS13410
gene id: 106370:FRANCCI3_RS13410
uniprot id: Q2J9M0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

106370:FRANCCI3 RS07630
gene id: 106370:FRANCCI3_RS07630
uniprot id: Q2JCU6
names: Similarity
messages: Belongs to the CobH/CbiC family.

106370:FRANCCI3 RS21825
gene id: 106370:FRANCCI3_RS21825
uniprot id: A0A1X1PX26
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS02585
gene id: 106370:FRANCCI3_RS02585
uniprot id: Q2JFN9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

106370:FRANCCI3 RS00395
gene id: 106370:FRANCCI3_RS00395
uniprot id: Q2JGW7
names: Similarity
messages: Belongs to the citrate synthase family.

106370:FRANCCI3 RS00255
gene id: 106370:FRANCCI3_RS00255
uniprot id: Q2JGZ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS06995
gene id: 106370:FRANCCI3_RS06995
uniprot id: Q2JD73
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

106370:FRANCCI3 RS05740
gene id: 106370:FRANCCI3_RS05740
uniprot id: Q2JDW5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

106370:FRANCCI3 RS06285
gene id: 106370:FRANCCI3_RS06285
uniprot id: Q2JDL0
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

106370:FRANCCI3 RS01335
gene id: 106370:FRANCCI3_RS01335
uniprot id: Q2JGD6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

106370:FRANCCI3 RS01420
gene id: 106370:FRANCCI3_RS01420
uniprot id: Q2JGC3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

106370:FRANCCI3 RS09590
gene id: 106370:FRANCCI3_RS09590
uniprot id: Q2JBQ7
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

106370:FRANCCI3 RS15210
gene id: 106370:FRANCCI3_RS15210
uniprot id: A0A1X1PV32
uniprot id: Q2J8L0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS01580
gene id: 106370:FRANCCI3_RS01580
uniprot id: Q2JG88
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

106370:FRANCCI3 RS05360
gene id: 106370:FRANCCI3_RS05360
uniprot id: Q2JE40
names: Similarity
messages: Belongs to the HypD family.

106370:FRANCCI3 RS13985
gene id: 106370:FRANCCI3_RS13985
uniprot id: Q2J9A2
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

106370:FRANCCI3 RS18610
gene id: 106370:FRANCCI3_RS18610
uniprot id: Q2J6Q6
names: Similarity
messages: Belongs to the UPF0045 family.

106370:FRANCCI3 RS13020
gene id: 106370:FRANCCI3_RS13020
uniprot id: Q2J9U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

106370:FRANCCI3 RS11045
gene id: 106370:FRANCCI3_RS11045
uniprot id: Q2JAX4
names: Similarity
messages: Belongs to the peptidase S33 family.

106370:FRANCCI3 RS12205
gene id: 106370:FRANCCI3_RS12205
uniprot id: Q2JA98
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

106370:FRANCCI3 RS10645
gene id: 106370:FRANCCI3_RS10645
uniprot id: Q2JB53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

106370:FRANCCI3 RS05110
gene id: 106370:FRANCCI3_RS05110
uniprot id: A0A1X1PVU4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS22545
gene id: 106370:FRANCCI3_RS22545
uniprot id: Q2J4J2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

106370:FRANCCI3 RS19220
gene id: 106370:FRANCCI3_RS19220
uniprot id: Q2J6D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

106370:FRANCCI3 RS15945
gene id: 106370:FRANCCI3_RS15945
uniprot id: Q2J866
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

106370:FRANCCI3 RS02795
gene id: 106370:FRANCCI3_RS02795
uniprot id: Q2JFJ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS14610
gene id: 106370:FRANCCI3_RS14610
uniprot id: A0A1X1PYN8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS07785
gene id: 106370:FRANCCI3_RS07785
uniprot id: Q2JCR7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

106370:FRANCCI3 RS17915
gene id: 106370:FRANCCI3_RS17915
uniprot id: Q2J740
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

106370:FRANCCI3 RS19860
gene id: 106370:FRANCCI3_RS19860
uniprot id: Q2J606
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS08265
gene id: 106370:FRANCCI3_RS08265
uniprot id: Q2JCH1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

106370:FRANCCI3 RS01425
gene id: 106370:FRANCCI3_RS01425
uniprot id: Q2JGC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

106370:FRANCCI3 RS07560
gene id: 106370:FRANCCI3_RS07560
uniprot id: Q2JCW0
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS21760
gene id: 106370:FRANCCI3_RS21760
uniprot id: Q2J4Z2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

106370:FRANCCI3 RS15975
gene id: 106370:FRANCCI3_RS15975
uniprot id: Q2J860
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

106370:FRANCCI3 RS11135
gene id: 106370:FRANCCI3_RS11135
uniprot id: A0A1X1PW53
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS17465
gene id: 106370:FRANCCI3_RS17465
uniprot id: Q2J7C9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

106370:FRANCCI3 RS18110
gene id: 106370:FRANCCI3_RS18110
uniprot id: Q2J702
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

106370:FRANCCI3 RS18440
gene id: 106370:FRANCCI3_RS18440
uniprot id: Q2J6T8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Heterodimer of an alpha and a beta chain.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS03400
gene id: 106370:FRANCCI3_RS03400
uniprot id: Q2JF82
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106370:FRANCCI3 RS09555
gene id: 106370:FRANCCI3_RS09555
uniprot id: Q2JBR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS16845
gene id: 106370:FRANCCI3_RS16845
uniprot id: Q2J7P3
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

106370:FRANCCI3 RS24420
gene id: 106370:FRANCCI3_RS24420
uniprot id: Q2JBE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

106370:FRANCCI3 RS07120
gene id: 106370:FRANCCI3_RS07120
uniprot id: Q2JD49
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

106370:FRANCCI3 RS16010
gene id: 106370:FRANCCI3_RS16010
uniprot id: A0A1X1PZ48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS27860
gene id: 106370:FRANCCI3_RS27860
uniprot id: A0A1X1Q0T3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS16905
gene id: 106370:FRANCCI3_RS16905
uniprot id: Q2J7N1
names: Similarity
messages: Belongs to the peptidase S33 family.

106370:FRANCCI3 RS11320
gene id: 106370:FRANCCI3_RS11320
uniprot id: Q2JAS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

106370:FRANCCI3 RS06745
gene id: 106370:FRANCCI3_RS06745
uniprot id: Q2JDB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

106370:FRANCCI3 RS04590
gene id: 106370:FRANCCI3_RS04590
uniprot id: Q2JEJ1
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS08915
gene id: 106370:FRANCCI3_RS08915
uniprot id: Q2JC47
names: Similarity
messages: Belongs to the cytochrome P450 family.

106370:FRANCCI3 RS06880
gene id: 106370:FRANCCI3_RS06880
uniprot id: Q2JD95
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

106370:FRANCCI3 RS12410
gene id: 106370:FRANCCI3_RS12410
uniprot id: A0A1X1PYS8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS05770
gene id: 106370:FRANCCI3_RS05770
uniprot id: Q2JDV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

106370:FRANCCI3 RS08060
gene id: 106370:FRANCCI3_RS08060
uniprot id: Q2JCL1
names: Similarity
messages: Belongs to the CFA/CMAS family.

106370:FRANCCI3 RS04355
gene id: 106370:FRANCCI3_RS04355
uniprot id: Q2JEP0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

106370:FRANCCI3 RS02900
gene id: 106370:FRANCCI3_RS02900
uniprot id: A0A1X1PSY9
uniprot id: Q2JFI1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: With S4 and S5 plays an important role in translational accuracy.

106370:FRANCCI3 RS12335
gene id: 106370:FRANCCI3_RS12335
uniprot id: Q2JA71
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

106370:FRANCCI3 RS02100
gene id: 106370:FRANCCI3_RS02100
uniprot id: Q2JFY4
names: Similarity
messages: Belongs to the P(II) protein family.

106370:FRANCCI3 RS14455
gene id: 106370:FRANCCI3_RS14455
uniprot id: Q2J907
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

106370:FRANCCI3 RS10230
gene id: 106370:FRANCCI3_RS10230
uniprot id: Q2JBD4
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

106370:FRANCCI3 RS07810
gene id: 106370:FRANCCI3_RS07810
uniprot id: Q2JCR2
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS19545
gene id: 106370:FRANCCI3_RS19545
uniprot id: Q2J671
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

106370:FRANCCI3 RS11160
gene id: 106370:FRANCCI3_RS11160
uniprot id: Q2JAV2
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

106370:FRANCCI3 RS06150
gene id: 106370:FRANCCI3_RS06150
uniprot id: Q2JDN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

106370:FRANCCI3 RS00475
gene id: 106370:FRANCCI3_RS00475
uniprot id: Q2JGV1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

106370:FRANCCI3 RS11015
gene id: 106370:FRANCCI3_RS11015
uniprot id: Q2JAY0
names: Similarity
messages: Belongs to the HepT RNase toxin family.

106370:FRANCCI3 RS14450
gene id: 106370:FRANCCI3_RS14450
uniprot id: Q2J908
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

106370:FRANCCI3 RS22045
gene id: 106370:FRANCCI3_RS22045
uniprot id: Q2J4U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

106370:FRANCCI3 RS12380
gene id: 106370:FRANCCI3_RS12380
uniprot id: Q2JA62
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

106370:FRANCCI3 RS17865
gene id: 106370:FRANCCI3_RS17865
uniprot id: Q2J750
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

106370:FRANCCI3 RS01830
gene id: 106370:FRANCCI3_RS01830
uniprot id: Q2JG36
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

106370:FRANCCI3 RS07105
gene id: 106370:FRANCCI3_RS07105
uniprot id: A0A1X1PQP5
uniprot id: Q2JD52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS09460
gene id: 106370:FRANCCI3_RS09460
uniprot id: A0A1X1PUM2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS19100
gene id: 106370:FRANCCI3_RS19100
uniprot id: Q2J6G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

106370:FRANCCI3 RS03270
gene id: 106370:FRANCCI3_RS03270
uniprot id: Q2JFA7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

106370:FRANCCI3 RS06585
gene id: 106370:FRANCCI3_RS06585
uniprot id: Q2JDF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

106370:FRANCCI3 RS02880
gene id: 106370:FRANCCI3_RS02880
uniprot id: Q2JFI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

106370:FRANCCI3 RS18950
gene id: 106370:FRANCCI3_RS18950
uniprot id: Q2J6J0
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

106370:FRANCCI3 RS22825
gene id: 106370:FRANCCI3_RS22825
uniprot id: Q2J4D5
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

106370:FRANCCI3 RS20040
gene id: 106370:FRANCCI3_RS20040
uniprot id: Q2J5X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

106370:FRANCCI3 RS07645
gene id: 106370:FRANCCI3_RS07645
uniprot id: Q2JCU3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

106370:FRANCCI3 RS08250
gene id: 106370:FRANCCI3_RS08250
uniprot id: Q2JCH4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

106370:FRANCCI3 RS06915
gene id: 106370:FRANCCI3_RS06915
uniprot id: Q2JD88
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

106370:FRANCCI3 RS08320
gene id: 106370:FRANCCI3_RS08320
uniprot id: A0A1X1PZN2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS03220
gene id: 106370:FRANCCI3_RS03220
uniprot id: Q2JFB7
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

106370:FRANCCI3 RS07380
gene id: 106370:FRANCCI3_RS07380
uniprot id: Q2JCZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

106370:FRANCCI3 RS13040
gene id: 106370:FRANCCI3_RS13040
uniprot id: Q2J9U3
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

106370:FRANCCI3 RS21765
gene id: 106370:FRANCCI3_RS21765
uniprot id: Q2J4Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

106370:FRANCCI3 RS17840
gene id: 106370:FRANCCI3_RS17840
uniprot id: A0A1X1PWE7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS03470
gene id: 106370:FRANCCI3_RS03470
uniprot id: Q2JF68
names: Similarity
messages: Belongs to the phosphohexose mutase family.

106370:FRANCCI3 RS08230
gene id: 106370:FRANCCI3_RS08230
uniprot id: A0A1X1PZL4
uniprot id: Q2JCH8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS00560
gene id: 106370:FRANCCI3_RS00560
uniprot id: Q2JGT6
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

106370:FRANCCI3 RS00985
gene id: 106370:FRANCCI3_RS00985
uniprot id: Q2JGK8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

106370:FRANCCI3 RS04575
gene id: 106370:FRANCCI3_RS04575
uniprot id: Q2JEJ4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

106370:FRANCCI3 RS09790
gene id: 106370:FRANCCI3_RS09790
uniprot id: Q2JBL9
names: Similarity
messages: Belongs to the HypE family.

106370:FRANCCI3 RS17370
gene id: 106370:FRANCCI3_RS17370
uniprot id: Q2J7E7
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

106370:FRANCCI3 RS22625
gene id: 106370:FRANCCI3_RS22625
uniprot id: Q2J4H4
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

106370:FRANCCI3 RS23005
gene id: 106370:FRANCCI3_RS23005
uniprot id: Q2J4A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

106370:FRANCCI3 RS26185
gene id: 106370:FRANCCI3_RS26185
uniprot id: A0A1X1PSV3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS12445
gene id: 106370:FRANCCI3_RS12445
uniprot id: Q2JA48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

106370:FRANCCI3 RS15615
gene id: 106370:FRANCCI3_RS15615
uniprot id: Q2J8C8
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

106370:FRANCCI3 RS02910
gene id: 106370:FRANCCI3_RS02910
uniprot id: Q2JFH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

106370:FRANCCI3 RS11710
gene id: 106370:FRANCCI3_RS11710
uniprot id: A0A1X1PT48
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS06180
gene id: 106370:FRANCCI3_RS06180
uniprot id: A0A1X1Q0T7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS13130
gene id: 106370:FRANCCI3_RS13130
uniprot id: Q2J9S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

106370:FRANCCI3 RS02345
gene id: 106370:FRANCCI3_RS02345
uniprot id: Q2JFT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

106370:FRANCCI3 RS06895
gene id: 106370:FRANCCI3_RS06895
uniprot id: Q2JD92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

106370:FRANCCI3 RS00205
gene id: 106370:FRANCCI3_RS00205
uniprot id: Q2JH05
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

106370:FRANCCI3 RS15700
gene id: 106370:FRANCCI3_RS15700
uniprot id: Q2J8B1
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

106370:FRANCCI3 RS05030
gene id: 106370:FRANCCI3_RS05030
uniprot id: Q2JEA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

106370:FRANCCI3 RS12105
gene id: 106370:FRANCCI3_RS12105
uniprot id: Q2JAB8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

106370:FRANCCI3 RS15200
gene id: 106370:FRANCCI3_RS15200
uniprot id: Q2J8L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

106370:FRANCCI3 RS19490
gene id: 106370:FRANCCI3_RS19490
uniprot id: Q2J682
names: Similarity
messages: Belongs to the UPF0162 family.

106370:FRANCCI3 RS06420
gene id: 106370:FRANCCI3_RS06420
uniprot id: Q2JDI3
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

106370:FRANCCI3 RS22730
gene id: 106370:FRANCCI3_RS22730
uniprot id: Q2J4F2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

106370:FRANCCI3 RS23015
gene id: 106370:FRANCCI3_RS23015
uniprot id: A0A1X1PVE6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS05355
gene id: 106370:FRANCCI3_RS05355
uniprot id: Q2JE41
names: Similarity
messages: Belongs to the HypE family.

106370:FRANCCI3 RS14475
gene id: 106370:FRANCCI3_RS14475
uniprot id: Q2J904
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

106370:FRANCCI3 RS11285
gene id: 106370:FRANCCI3_RS11285
uniprot id: Q2JAS7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

106370:FRANCCI3 RS13160
gene id: 106370:FRANCCI3_RS13160
uniprot id: Q2J9R8
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

106370:FRANCCI3 RS19575
gene id: 106370:FRANCCI3_RS19575
uniprot id: A0A1X1PTA4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS11405
gene id: 106370:FRANCCI3_RS11405
uniprot id: Q2JAQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

106370:FRANCCI3 RS00885
gene id: 106370:FRANCCI3_RS00885
uniprot id: Q2JGM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

106370:FRANCCI3 RS11480
gene id: 106370:FRANCCI3_RS11480
uniprot id: A0A1X1PZ07
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS10670
gene id: 106370:FRANCCI3_RS10670
uniprot id: Q2JB48
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

106370:FRANCCI3 RS16000
gene id: 106370:FRANCCI3_RS16000
uniprot id: Q2J855
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

106370:FRANCCI3 RS12440
gene id: 106370:FRANCCI3_RS12440
uniprot id: Q2JA49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

106370:FRANCCI3 RS11530
gene id: 106370:FRANCCI3_RS11530
uniprot id: Q2JAM9
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

106370:FRANCCI3 RS01285
gene id: 106370:FRANCCI3_RS01285
uniprot id: Q2JGE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

106370:FRANCCI3 RS19550
gene id: 106370:FRANCCI3_RS19550
uniprot id: Q2J670
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

106370:FRANCCI3 RS22605
gene id: 106370:FRANCCI3_RS22605
uniprot id: Q2J4H9
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

106370:FRANCCI3 RS17030
gene id: 106370:FRANCCI3_RS17030
uniprot id: Q2J7K6
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

106370:FRANCCI3 RS06695
gene id: 106370:FRANCCI3_RS06695
uniprot id: Q2JDC9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

106370:FRANCCI3 RS17315
gene id: 106370:FRANCCI3_RS17315
uniprot id: Q2J7F8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

106370:FRANCCI3 RS26580
gene id: 106370:FRANCCI3_RS26580
uniprot id: A0A1X1PQV7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS02975
gene id: 106370:FRANCCI3_RS02975
uniprot id: Q2JFG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

106370:FRANCCI3 RS06395
gene id: 106370:FRANCCI3_RS06395
uniprot id: Q2JDI9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

106370:FRANCCI3 RS04290
gene id: 106370:FRANCCI3_RS04290
uniprot id: Q2JEQ3
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS24975
gene id: 106370:FRANCCI3_RS24975
uniprot id: A0A1X1PWW2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS02740
gene id: 106370:FRANCCI3_RS02740
uniprot id: Q2JFK9
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS27590
gene id: 106370:FRANCCI3_RS27590
uniprot id: A0A1X1PUC9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS09595
gene id: 106370:FRANCCI3_RS09595
uniprot id: Q2JBQ6
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

106370:FRANCCI3 RS04260
gene id: 106370:FRANCCI3_RS04260
uniprot id: Q2JER0
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

106370:FRANCCI3 RS03415
gene id: 106370:FRANCCI3_RS03415
uniprot id: Q2JF79
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

106370:FRANCCI3 RS06690
gene id: 106370:FRANCCI3_RS06690
uniprot id: Q2JDD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

106370:FRANCCI3 RS06360
gene id: 106370:FRANCCI3_RS06360
uniprot id: Q2JDJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

106370:FRANCCI3 RS06340
gene id: 106370:FRANCCI3_RS06340
uniprot id: Q2JDK0
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

106370:FRANCCI3 RS13115
gene id: 106370:FRANCCI3_RS13115
uniprot id: Q2J9S7
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

106370:FRANCCI3 RS11660
gene id: 106370:FRANCCI3_RS11660
uniprot id: Q2JAK2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

106370:FRANCCI3 RS00125
gene id: 106370:FRANCCI3_RS00125
uniprot id: Q2JH25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

106370:FRANCCI3 RS18215
gene id: 106370:FRANCCI3_RS18215
uniprot id: Q2J6Y1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

106370:FRANCCI3 RS19050
gene id: 106370:FRANCCI3_RS19050
uniprot id: Q2J6H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

106370:FRANCCI3 RS13690
gene id: 106370:FRANCCI3_RS13690
uniprot id: Q2J9G3
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS06865
gene id: 106370:FRANCCI3_RS06865
uniprot id: Q2JD98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

106370:FRANCCI3 RS22690
gene id: 106370:FRANCCI3_RS22690
uniprot id: Q2J4G1
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

106370:FRANCCI3 RS19190
gene id: 106370:FRANCCI3_RS19190
uniprot id: Q2J6E3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

106370:FRANCCI3 RS10625
gene id: 106370:FRANCCI3_RS10625
uniprot id: A0A1X1PTZ9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS04845
gene id: 106370:FRANCCI3_RS04845
uniprot id: Q2JEE0
names: Similarity
messages: Belongs to the peptidase M1 family.

106370:FRANCCI3 RS13060
gene id: 106370:FRANCCI3_RS13060
uniprot id: Q2J9T9
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

106370:FRANCCI3 RS08425
gene id: 106370:FRANCCI3_RS08425
uniprot id: Q2JCD8
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

106370:FRANCCI3 RS18515
gene id: 106370:FRANCCI3_RS18515
uniprot id: Q2J6S6
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

106370:FRANCCI3 RS15170
gene id: 106370:FRANCCI3_RS15170
uniprot id: A0A1X1PXX4
names: Caution
names: Similarity
messages: Belongs to the TrpC family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS24210
gene id: 106370:FRANCCI3_RS24210
uniprot id: A0A1X1Q0A1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS03295
gene id: 106370:FRANCCI3_RS03295
uniprot id: Q2JFA2
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS02145
gene id: 106370:FRANCCI3_RS02145
uniprot id: Q2JFX7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS02555
gene id: 106370:FRANCCI3_RS02555
uniprot id: A0A1X1PRL6
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS13915
gene id: 106370:FRANCCI3_RS13915
uniprot id: Q2J9B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

106370:FRANCCI3 RS00630
gene id: 106370:FRANCCI3_RS00630
uniprot id: Q2JGS4
names: Similarity
messages: Belongs to the AAA ATPase family.

106370:FRANCCI3 RS16030
gene id: 106370:FRANCCI3_RS16030
uniprot id: Q2J850
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

106370:FRANCCI3 RS20720
gene id: 106370:FRANCCI3_RS20720
uniprot id: Q2J5J3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

106370:FRANCCI3 RS07825
gene id: 106370:FRANCCI3_RS07825
uniprot id: Q2JCQ9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106370:FRANCCI3 RS06040
gene id: 106370:FRANCCI3_RS06040
uniprot id: Q2JDQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

106370:FRANCCI3 RS22090
gene id: 106370:FRANCCI3_RS22090
uniprot id: Q2J4T1
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

106370:FRANCCI3 RS00275
gene id: 106370:FRANCCI3_RS00275
uniprot id: Q2JGZ2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

106370:FRANCCI3 RS22465
gene id: 106370:FRANCCI3_RS22465
uniprot id: Q2J4K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

106370:FRANCCI3 RS00245
gene id: 106370:FRANCCI3_RS00245
uniprot id: Q2JGZ8
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

106370:FRANCCI3 RS16565
gene id: 106370:FRANCCI3_RS16565
uniprot id: Q2J7U0
names: Similarity
messages: Belongs to the HIBADH-related family.

106370:FRANCCI3 RS02840
gene id: 106370:FRANCCI3_RS02840
uniprot id: Q2JFJ2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

106370:FRANCCI3 RS15185
gene id: 106370:FRANCCI3_RS15185
uniprot id: Q2J8L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

106370:FRANCCI3 RS18690
gene id: 106370:FRANCCI3_RS18690
uniprot id: Q2J6N9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

106370:FRANCCI3 RS18720
gene id: 106370:FRANCCI3_RS18720
uniprot id: A0A1X1Q184
uniprot id: Q2J6N4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS11215
gene id: 106370:FRANCCI3_RS11215
uniprot id: Q2JAU1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

106370:FRANCCI3 RS23590
gene id: 106370:FRANCCI3_RS23590
uniprot id: Q2J865
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

106370:FRANCCI3 RS03505
gene id: 106370:FRANCCI3_RS03505
uniprot id: Q2JF62
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

106370:FRANCCI3 RS22255
gene id: 106370:FRANCCI3_RS22255
uniprot id: Q2J4P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

106370:FRANCCI3 RS15440
gene id: 106370:FRANCCI3_RS15440
uniprot id: A0A1X1PZF7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS23080
gene id: 106370:FRANCCI3_RS23080
uniprot id: Q2JG90
names: Similarity
messages: Belongs to the glutamine synthetase family.

106370:FRANCCI3 RS18180
gene id: 106370:FRANCCI3_RS18180
uniprot id: Q2J6Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

106370:FRANCCI3 RS15745
gene id: 106370:FRANCCI3_RS15745
uniprot id: Q2J8A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

106370:FRANCCI3 RS12430
gene id: 106370:FRANCCI3_RS12430
uniprot id: Q2JA51
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

106370:FRANCCI3 RS16360
gene id: 106370:FRANCCI3_RS16360
uniprot id: A0A1X1PVI9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS03900
gene id: 106370:FRANCCI3_RS03900
uniprot id: Q2JEY3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS02340
gene id: 106370:FRANCCI3_RS02340
uniprot id: A0A1X1PSM9
names: Caution
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS03015
gene id: 106370:FRANCCI3_RS03015
uniprot id: Q2JFF8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

106370:FRANCCI3 RS17645
gene id: 106370:FRANCCI3_RS17645
uniprot id: Q2J793
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

106370:FRANCCI3 RS22165
gene id: 106370:FRANCCI3_RS22165
uniprot id: Q2J4R7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

106370:FRANCCI3 RS15795
gene id: 106370:FRANCCI3_RS15795
uniprot id: Q2J893
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

106370:FRANCCI3 RS22100
gene id: 106370:FRANCCI3_RS22100
uniprot id: A0A1X1Q1R6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS18135
gene id: 106370:FRANCCI3_RS18135
uniprot id: Q2J6Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

106370:FRANCCI3 RS21510
gene id: 106370:FRANCCI3_RS21510
uniprot id: Q2J542
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

106370:FRANCCI3 RS03175
gene id: 106370:FRANCCI3_RS03175
uniprot id: Q2JFC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

106370:FRANCCI3 RS16470
gene id: 106370:FRANCCI3_RS16470
uniprot id: Q2J7V9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

106370:FRANCCI3 RS08745
gene id: 106370:FRANCCI3_RS08745
uniprot id: Q2JC82
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS16400
gene id: 106370:FRANCCI3_RS16400
uniprot id: Q2J7X5
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS15650
gene id: 106370:FRANCCI3_RS15650
uniprot id: Q2J8C1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS22870
gene id: 106370:FRANCCI3_RS22870
uniprot id: A0A1X1PR30
uniprot id: Q2J4C6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS17585
gene id: 106370:FRANCCI3_RS17585
uniprot id: Q2J7A5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

106370:FRANCCI3 RS06910
gene id: 106370:FRANCCI3_RS06910
uniprot id: Q2JD89
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

106370:FRANCCI3 RS07495
gene id: 106370:FRANCCI3_RS07495
uniprot id: Q2JCX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

106370:FRANCCI3 RS06080
gene id: 106370:FRANCCI3_RS06080
uniprot id: Q2JDQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

106370:FRANCCI3 RS22490
gene id: 106370:FRANCCI3_RS22490
uniprot id: Q2J4K2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

106370:FRANCCI3 RS05395
gene id: 106370:FRANCCI3_RS05395
uniprot id: Q2JE33
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

106370:FRANCCI3 RS15935
gene id: 106370:FRANCCI3_RS15935
uniprot id: A0A1X1PZM4
uniprot id: Q2J868
names: Caution
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS06345
gene id: 106370:FRANCCI3_RS06345
uniprot id: Q2JDJ9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

106370:FRANCCI3 RS19485
gene id: 106370:FRANCCI3_RS19485
uniprot id: Q2J684
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

106370:FRANCCI3 RS13105
gene id: 106370:FRANCCI3_RS13105
uniprot id: Q2J9S9
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS04735
gene id: 106370:FRANCCI3_RS04735
uniprot id: Q2JEG1
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS09750
gene id: 106370:FRANCCI3_RS09750
uniprot id: Q2JBM6
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

106370:FRANCCI3 RS01005
gene id: 106370:FRANCCI3_RS01005
uniprot id: Q2JGK4
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS21495
gene id: 106370:FRANCCI3_RS21495
uniprot id: A0A1X1PYJ8
uniprot id: Q2J545
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS05250
gene id: 106370:FRANCCI3_RS05250
uniprot id: Q2JE62
names: Similarity
messages: Belongs to the pirin family.

106370:FRANCCI3 RS18910
gene id: 106370:FRANCCI3_RS18910
uniprot id: Q2J6J7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

106370:FRANCCI3 RS21795
gene id: 106370:FRANCCI3_RS21795
uniprot id: Q2J4Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

106370:FRANCCI3 RS15755
gene id: 106370:FRANCCI3_RS15755
uniprot id: Q2J8A1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

106370:FRANCCI3 RS10425
gene id: 106370:FRANCCI3_RS10425
uniprot id: Q2JB98
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

106370:FRANCCI3 RS15875
gene id: 106370:FRANCCI3_RS15875
uniprot id: Q2J877
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

106370:FRANCCI3 RS15815
gene id: 106370:FRANCCI3_RS15815
uniprot id: Q2J889
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS02945
gene id: 106370:FRANCCI3_RS02945
uniprot id: Q2JFH2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

106370:FRANCCI3 RS22150
gene id: 106370:FRANCCI3_RS22150
uniprot id: A0A1X1Q1N7
uniprot id: Q2J4S0
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS06115
gene id: 106370:FRANCCI3_RS06115
uniprot id: A0A1X1Q0W0
uniprot id: Q2JDP4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This protein binds to 23S rRNA in the presence of protein L20.

106370:FRANCCI3 RS02785
gene id: 106370:FRANCCI3_RS02785
uniprot id: Q2JFK0
names: Similarity
messages: Belongs to the UPF0234 family.

106370:FRANCCI3 RS12415
gene id: 106370:FRANCCI3_RS12415
uniprot id: Q2JA54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

106370:FRANCCI3 RS03930
gene id: 106370:FRANCCI3_RS03930
uniprot id: Q2JEX7
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS22700
gene id: 106370:FRANCCI3_RS22700
uniprot id: Q2J4F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

106370:FRANCCI3 RS20595
gene id: 106370:FRANCCI3_RS20595
uniprot id: Q2J5L6
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS19075
gene id: 106370:FRANCCI3_RS19075
uniprot id: Q2J6G4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

106370:FRANCCI3 RS16870
gene id: 106370:FRANCCI3_RS16870
uniprot id: Q2J7N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

106370:FRANCCI3 RS27520
gene id: 106370:FRANCCI3_RS27520
uniprot id: Q2J8V7
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

106370:FRANCCI3 RS06425
gene id: 106370:FRANCCI3_RS06425
uniprot id: Q2JDI2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

106370:FRANCCI3 RS23260
gene id: 106370:FRANCCI3_RS23260
uniprot id: Q2JD67
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

106370:FRANCCI3 RS14550
gene id: 106370:FRANCCI3_RS14550
uniprot id: A0A1X1PYP6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS07540
gene id: 106370:FRANCCI3_RS07540
uniprot id: Q2JCW4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

106370:FRANCCI3 RS05025
gene id: 106370:FRANCCI3_RS05025
uniprot id: Q2JEA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

106370:FRANCCI3 RS16055
gene id: 106370:FRANCCI3_RS16055
uniprot id: Q2J845
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

106370:FRANCCI3 RS00260
gene id: 106370:FRANCCI3_RS00260
uniprot id: Q2JGZ5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

106370:FRANCCI3 RS06890
gene id: 106370:FRANCCI3_RS06890
uniprot id: Q2JD93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

106370:FRANCCI3 RS16065
gene id: 106370:FRANCCI3_RS16065
uniprot id: Q2J843
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

106370:FRANCCI3 RS11580
gene id: 106370:FRANCCI3_RS11580
uniprot id: Q2JAL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

106370:FRANCCI3 RS07285
gene id: 106370:FRANCCI3_RS07285
uniprot id: Q2JD16
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

106370:FRANCCI3 RS02780
gene id: 106370:FRANCCI3_RS02780
uniprot id: Q2JFK1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

106370:FRANCCI3 RS14425
gene id: 106370:FRANCCI3_RS14425
uniprot id: Q2J913
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS02745
gene id: 106370:FRANCCI3_RS02745
uniprot id: Q2JFK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

106370:FRANCCI3 RS00020
gene id: 106370:FRANCCI3_RS00020
uniprot id: Q2JH45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

106370:FRANCCI3 RS21505
gene id: 106370:FRANCCI3_RS21505
uniprot id: Q2J543
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

106370:FRANCCI3 RS08395
gene id: 106370:FRANCCI3_RS08395
uniprot id: Q2JCE5
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS04135
gene id: 106370:FRANCCI3_RS04135
uniprot id: Q2JET6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

106370:FRANCCI3 RS11250
gene id: 106370:FRANCCI3_RS11250
uniprot id: Q2JAT4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

106370:FRANCCI3 RS17695
gene id: 106370:FRANCCI3_RS17695
uniprot id: Q2J783
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

106370:FRANCCI3 RS17905
gene id: 106370:FRANCCI3_RS17905
uniprot id: Q2J742
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

106370:FRANCCI3 RS10500
gene id: 106370:FRANCCI3_RS10500
uniprot id: Q2JB84
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS16060
gene id: 106370:FRANCCI3_RS16060
uniprot id: Q2J844
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS05555
gene id: 106370:FRANCCI3_RS05555
uniprot id: Q2JE00
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

106370:FRANCCI3 RS17985
gene id: 106370:FRANCCI3_RS17985
uniprot id: Q2J728
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

106370:FRANCCI3 RS02485
gene id: 106370:FRANCCI3_RS02485
uniprot id: A0A1X1PS67
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS19735
gene id: 106370:FRANCCI3_RS19735
uniprot id: Q2J631
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

106370:FRANCCI3 RS04705
gene id: 106370:FRANCCI3_RS04705
uniprot id: Q2JEG8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

106370:FRANCCI3 RS02935
gene id: 106370:FRANCCI3_RS02935
uniprot id: Q2JFH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

106370:FRANCCI3 RS00905
gene id: 106370:FRANCCI3_RS00905
uniprot id: Q2JGL9
names: Similarity
messages: Belongs to the group II decarboxylase family.

106370:FRANCCI3 RS00695
gene id: 106370:FRANCCI3_RS00695
uniprot id: A0A1X1PR55
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS03635
gene id: 106370:FRANCCI3_RS03635
uniprot id: Q2JF35
names: Similarity
messages: Belongs to the ABC transporter superfamily.

106370:FRANCCI3 RS14650
gene id: 106370:FRANCCI3_RS14650
uniprot id: Q2J8X1
names: Similarity
messages: Belongs to the glutamate synthase family.

106370:FRANCCI3 RS05410
gene id: 106370:FRANCCI3_RS05410
uniprot id: A0A1X1PZA8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS13850
gene id: 106370:FRANCCI3_RS13850
uniprot id: Q2J9D0
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS09670
gene id: 106370:FRANCCI3_RS09670
uniprot id: Q2JBP2
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.

106370:FRANCCI3 RS06120
gene id: 106370:FRANCCI3_RS06120
uniprot id: Q2JDP3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

106370:FRANCCI3 RS08305
gene id: 106370:FRANCCI3_RS08305
uniprot id: Q2JCG3
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS02990
gene id: 106370:FRANCCI3_RS02990
uniprot id: A0A1X1Q1G5
uniprot id: Q2JFG3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS21565
gene id: 106370:FRANCCI3_RS21565
uniprot id: A0A1X1PYD7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS14635
gene id: 106370:FRANCCI3_RS14635
uniprot id: Q2J8X3
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: In the N-terminal section; belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

106370:FRANCCI3 RS17785
gene id: 106370:FRANCCI3_RS17785
uniprot id: Q2J765
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

106370:FRANCCI3 RS07350
gene id: 106370:FRANCCI3_RS07350
uniprot id: Q2JD04
names: Similarity
messages: Belongs to the peptidase C40 family.

106370:FRANCCI3 RS06575
gene id: 106370:FRANCCI3_RS06575
uniprot id: Q2JDF2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

106370:FRANCCI3 RS22735
gene id: 106370:FRANCCI3_RS22735
uniprot id: Q2J4F1
names: Similarity
messages: Belongs to the peptidase A31 family.

106370:FRANCCI3 RS05815
gene id: 106370:FRANCCI3_RS05815
uniprot id: Q2JDV1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

106370:FRANCCI3 RS02905
gene id: 106370:FRANCCI3_RS02905
uniprot id: Q2JFI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

106370:FRANCCI3 RS01310
gene id: 106370:FRANCCI3_RS01310
uniprot id: Q2JGE2
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

106370:FRANCCI3 RS06125
gene id: 106370:FRANCCI3_RS06125
uniprot id: Q2JDP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

106370:FRANCCI3 RS12545
gene id: 106370:FRANCCI3_RS12545
uniprot id: Q2JA27
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

106370:FRANCCI3 RS18560
gene id: 106370:FRANCCI3_RS18560
uniprot id: Q2J6R7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

106370:FRANCCI3 RS22660
gene id: 106370:FRANCCI3_RS22660
uniprot id: Q2J4G7
names: Similarity
messages: Belongs to the NifZ family.

106370:FRANCCI3 RS22665
gene id: 106370:FRANCCI3_RS22665
uniprot id: A0A1X1PW20
uniprot id: Q2J4G6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifW family.
messages: Homotrimer; associates with NifD.
messages: May protect the nitrogenase Fe-Mo protein from oxidative damage.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS02730
gene id: 106370:FRANCCI3_RS02730
uniprot id: Q2JFL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

106370:FRANCCI3 RS06715
gene id: 106370:FRANCCI3_RS06715
uniprot id: A0A1X1PW95
names: Caution
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS09525
gene id: 106370:FRANCCI3_RS09525
uniprot id: Q2JBS0
names: Similarity
messages: Belongs to the UPF0235 family.

106370:FRANCCI3 RS18175
gene id: 106370:FRANCCI3_RS18175
uniprot id: Q2J6Z0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

106370:FRANCCI3 RS07830
gene id: 106370:FRANCCI3_RS07830
uniprot id: Q2JCQ8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

106370:FRANCCI3 RS20905
gene id: 106370:FRANCCI3_RS20905
uniprot id: Q2J5F6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106370:FRANCCI3 RS15830
gene id: 106370:FRANCCI3_RS15830
uniprot id: Q2J886
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

106370:FRANCCI3 RS07435
gene id: 106370:FRANCCI3_RS07435
uniprot id: Q2JCY7
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

106370:FRANCCI3 RS02080
gene id: 106370:FRANCCI3_RS02080
uniprot id: Q2JFY7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS06480
gene id: 106370:FRANCCI3_RS06480
uniprot id: Q2JDH1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

106370:FRANCCI3 RS03005
gene id: 106370:FRANCCI3_RS03005
uniprot id: A0A1X1Q1E1
uniprot id: Q2JFG0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

106370:FRANCCI3 RS15880
gene id: 106370:FRANCCI3_RS15880
uniprot id: Q2J876
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS21915
gene id: 106370:FRANCCI3_RS21915
uniprot id: Q2J4W3
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

106370:FRANCCI3 RS22530
gene id: 106370:FRANCCI3_RS22530
uniprot id: Q2J4J5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

106370:FRANCCI3 RS06365
gene id: 106370:FRANCCI3_RS06365
uniprot id: Q2JDJ5
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS01345
gene id: 106370:FRANCCI3_RS01345
uniprot id: Q2JGD4
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

106370:FRANCCI3 RS08180
gene id: 106370:FRANCCI3_RS08180
uniprot id: Q2JCI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

106370:FRANCCI3 RS21455
gene id: 106370:FRANCCI3_RS21455
uniprot id: A0A1X1PYG4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS18055
gene id: 106370:FRANCCI3_RS18055
uniprot id: Q2J713
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

106370:FRANCCI3 RS01735
gene id: 106370:FRANCCI3_RS01735
uniprot id: Q2JG56
names: Subcellular Location Annotation
messages: Cell membrane

106370:FRANCCI3 RS13250
gene id: 106370:FRANCCI3_RS13250
uniprot id: Q2J9Q0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that binds to protein Pup and functions as a docking station, an interdomain involved in ARC hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Homohexamer. Assembles into a hexameric ring structure that caps the 20S proteasome core. Strongly interacts with the prokaryotic ubiquitin-like protein Pup through a hydrophobic interface; the interacting region of ARC lies in its N-terminal coiled-coil domain. There is one Pup binding site per ARC hexamer ring. Upon ATP-binding, the C-terminus of ARC interacts with the alpha-rings of the proteasome core, possibly by binding to the intersubunit pockets.

106370:FRANCCI3 RS08240
gene id: 106370:FRANCCI3_RS08240
uniprot id: Q2JCH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106370:FRANCCI3 RS22120
gene id: 106370:FRANCCI3_RS22120
uniprot id: Q2J4S6
names: Similarity
messages: Belongs to the GARS family.

106370:FRANCCI3 RS00150
gene id: 106370:FRANCCI3_RS00150
uniprot id: Q2JH17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

106370:FRANCCI3 RS17780
gene id: 106370:FRANCCI3_RS17780
uniprot id: Q2J766
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

106370:FRANCCI3 RS08165
gene id: 106370:FRANCCI3_RS08165
uniprot id: Q2JCJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

106370:FRANCCI3 RS20505
gene id: 106370:FRANCCI3_RS20505
uniprot id: Q2J5N3
names: Similarity
messages: Belongs to the glutamine synthetase family.

106370:FRANCCI3 RS18815
gene id: 106370:FRANCCI3_RS18815
uniprot id: Q2J6L5
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

106370:FRANCCI3 RS16770
gene id: 106370:FRANCCI3_RS16770
uniprot id: Q2J7Q5
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS18275
gene id: 106370:FRANCCI3_RS18275
uniprot id: Q2J6W9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

106370:FRANCCI3 RS00955
gene id: 106370:FRANCCI3_RS00955
uniprot id: Q2JGL3
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

106370:FRANCCI3 RS22125
gene id: 106370:FRANCCI3_RS22125
uniprot id: Q2J4S5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

106370:FRANCCI3 RS18975
gene id: 106370:FRANCCI3_RS18975
uniprot id: A0A1X1PSA7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS06870
gene id: 106370:FRANCCI3_RS06870
uniprot id: Q2JD97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

106370:FRANCCI3 RS14820
gene id: 106370:FRANCCI3_RS14820
uniprot id: Q2J8T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

106370:FRANCCI3 RS18795
gene id: 106370:FRANCCI3_RS18795
uniprot id: A0A1X1PSI3
uniprot id: Q2J6L9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS16325
gene id: 106370:FRANCCI3_RS16325
uniprot id: Q2J7Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Membrane

106370:FRANCCI3 RS14260
gene id: 106370:FRANCCI3_RS14260
uniprot id: Q2J947
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

106370:FRANCCI3 RS17620
gene id: 106370:FRANCCI3_RS17620
uniprot id: Q2J798
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

106370:FRANCCI3 RS06050
gene id: 106370:FRANCCI3_RS06050
uniprot id: A0A1X1Q0N6
uniprot id: Q2JDQ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS17165
gene id: 106370:FRANCCI3_RS17165
uniprot id: Q2J7I4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

106370:FRANCCI3 RS22520
gene id: 106370:FRANCCI3_RS22520
uniprot id: A0A1X1PXD2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS22215
gene id: 106370:FRANCCI3_RS22215
uniprot id: Q2J4Q6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

106370:FRANCCI3 RS01700
gene id: 106370:FRANCCI3_RS01700
uniprot id: Q2JG63
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS21805
gene id: 106370:FRANCCI3_RS21805
uniprot id: Q2J4Y5
names: Similarity
messages: Belongs to the peptidase S13 family.

106370:FRANCCI3 RS18390
gene id: 106370:FRANCCI3_RS18390
uniprot id: Q2J6U8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

106370:FRANCCI3 RS22835
gene id: 106370:FRANCCI3_RS22835
uniprot id: Q2J4D3
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

106370:FRANCCI3 RS08605
gene id: 106370:FRANCCI3_RS08605
uniprot id: Q2JCA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

106370:FRANCCI3 RS13435
gene id: 106370:FRANCCI3_RS13435
uniprot id: Q2J9L4
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS15195
gene id: 106370:FRANCCI3_RS15195
uniprot id: Q2J8L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

106370:FRANCCI3 RS16045
gene id: 106370:FRANCCI3_RS16045
uniprot id: Q2J847
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS15430
gene id: 106370:FRANCCI3_RS15430
uniprot id: Q2J8G5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS15805
gene id: 106370:FRANCCI3_RS15805
uniprot id: Q2J891
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

106370:FRANCCI3 RS04080
gene id: 106370:FRANCCI3_RS04080
uniprot id: Q2JEU6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

106370:FRANCCI3 RS03905
gene id: 106370:FRANCCI3_RS03905
uniprot id: A0A1X1Q3C2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS15665
gene id: 106370:FRANCCI3_RS15665
uniprot id: Q2J8B8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

106370:FRANCCI3 RS06885
gene id: 106370:FRANCCI3_RS06885
uniprot id: Q2JD94
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

106370:FRANCCI3 RS02230
gene id: 106370:FRANCCI3_RS02230
uniprot id: A0A1X1PUN1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS17855
gene id: 106370:FRANCCI3_RS17855
uniprot id: Q2J752
names: Similarity
messages: Belongs to the CinA family.

106370:FRANCCI3 RS07115
gene id: 106370:FRANCCI3_RS07115
uniprot id: A0A1X1PR12
uniprot id: Q2JD50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS17720
gene id: 106370:FRANCCI3_RS17720
uniprot id: Q2J778
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

106370:FRANCCI3 RS14725
gene id: 106370:FRANCCI3_RS14725
uniprot id: Q2J8V6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA (By similarity).
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

106370:FRANCCI3 RS10715
gene id: 106370:FRANCCI3_RS10715
uniprot id: A0A1X1PTN7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS16095
gene id: 106370:FRANCCI3_RS16095
uniprot id: Q2J837
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS09720
gene id: 106370:FRANCCI3_RS09720
uniprot id: A0A1X1PXQ0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS09155
gene id: 106370:FRANCCI3_RS09155
uniprot id: Q2JBZ7
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

106370:FRANCCI3 RS04700
gene id: 106370:FRANCCI3_RS04700
uniprot id: Q2JEG9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

106370:FRANCCI3 RS22915
gene id: 106370:FRANCCI3_RS22915
uniprot id: Q2J4B7
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

106370:FRANCCI3 RS19385
gene id: 106370:FRANCCI3_RS19385
uniprot id: Q2J6A6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

106370:FRANCCI3 RS07320
gene id: 106370:FRANCCI3_RS07320
uniprot id: Q2JD09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

106370:FRANCCI3 RS08200
gene id: 106370:FRANCCI3_RS08200
uniprot id: Q2JCI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

106370:FRANCCI3 RS08310
gene id: 106370:FRANCCI3_RS08310
uniprot id: Q2JCG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

106370:FRANCCI3 RS18235
gene id: 106370:FRANCCI3_RS18235
uniprot id: Q2J6X7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS18740
gene id: 106370:FRANCCI3_RS18740
uniprot id: Q2J6N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

106370:FRANCCI3 RS12560
gene id: 106370:FRANCCI3_RS12560
uniprot id: Q2JA24
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS07460
gene id: 106370:FRANCCI3_RS07460
uniprot id: Q2JCY2
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

106370:FRANCCI3 RS02215
gene id: 106370:FRANCCI3_RS02215
uniprot id: Q2JFW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Monomer.

106370:FRANCCI3 RS19665
gene id: 106370:FRANCCI3_RS19665
uniprot id: Q2J645
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

106370:FRANCCI3 RS19905
gene id: 106370:FRANCCI3_RS19905
uniprot id: Q2J5Z7
names: Similarity
messages: Belongs to the peptidase S8 family.

106370:FRANCCI3 RS06075
gene id: 106370:FRANCCI3_RS06075
uniprot id: Q2JDQ2
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

106370:FRANCCI3 RS12210
gene id: 106370:FRANCCI3_RS12210
uniprot id: Q2JA97
names: Similarity
messages: Belongs to the PrpD family.

106370:FRANCCI3 RS22435
gene id: 106370:FRANCCI3_RS22435
uniprot id: Q2J4L3
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS18190
gene id: 106370:FRANCCI3_RS18190
uniprot id: Q2J6Y7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

106370:FRANCCI3 RS21550
gene id: 106370:FRANCCI3_RS21550
uniprot id: Q2J533
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

106370:FRANCCI3 RS20010
gene id: 106370:FRANCCI3_RS20010
uniprot id: Q2J5X9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

106370:FRANCCI3 RS02620
gene id: 106370:FRANCCI3_RS02620
uniprot id: Q2JFN3
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

106370:FRANCCI3 RS12855
gene id: 106370:FRANCCI3_RS12855
uniprot id: Q2J9X4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

106370:FRANCCI3 RS02705
gene id: 106370:FRANCCI3_RS02705
uniprot id: Q2JFL6
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

106370:FRANCCI3 RS02310
gene id: 106370:FRANCCI3_RS02310
uniprot id: Q2JFU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

106370:FRANCCI3 RS19625
gene id: 106370:FRANCCI3_RS19625
uniprot id: Q2J655
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

106370:FRANCCI3 RS14330
gene id: 106370:FRANCCI3_RS14330
uniprot id: Q2J933
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

106370:FRANCCI3 RS13890
gene id: 106370:FRANCCI3_RS13890
uniprot id: Q2J9C2
names: Similarity
messages: Belongs to the universal stress protein A family.

106370:FRANCCI3 RS18775
gene id: 106370:FRANCCI3_RS18775
uniprot id: Q2J6M3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS14360
gene id: 106370:FRANCCI3_RS14360
uniprot id: Q2J927
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

106370:FRANCCI3 RS16120
gene id: 106370:FRANCCI3_RS16120
uniprot id: Q2J832
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

106370:FRANCCI3 RS22860
gene id: 106370:FRANCCI3_RS22860
uniprot id: Q2J4C8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

106370:FRANCCI3 RS07800
gene id: 106370:FRANCCI3_RS07800
uniprot id: Q2JCR4
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

106370:FRANCCI3 RS03365
gene id: 106370:FRANCCI3_RS03365
uniprot id: Q2JF89
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

106370:FRANCCI3 RS19655
gene id: 106370:FRANCCI3_RS19655
uniprot id: Q2J647
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

106370:FRANCCI3 RS09355
gene id: 106370:FRANCCI3_RS09355
uniprot id: Q2JBV5
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

106370:FRANCCI3 RS22570
gene id: 106370:FRANCCI3_RS22570
uniprot id: A0A1X1PXE6
uniprot id: Q2J4I7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS22265
gene id: 106370:FRANCCI3_RS22265
uniprot id: Q2J4P6
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

106370:FRANCCI3 RS20095
gene id: 106370:FRANCCI3_RS20095
uniprot id: Q2J5W3
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS06320
gene id: 106370:FRANCCI3_RS06320
uniprot id: A0A1X1Q0T1
uniprot id: Q2JDK3
names: Caution
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS19475
gene id: 106370:FRANCCI3_RS19475
uniprot id: Q2J686
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

106370:FRANCCI3 RS08075
gene id: 106370:FRANCCI3_RS08075
uniprot id: Q2JCK8
names: Similarity
messages: Belongs to the cytochrome P450 family.

106370:FRANCCI3 RS18375
gene id: 106370:FRANCCI3_RS18375
uniprot id: Q2J6V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

106370:FRANCCI3 RS04225
gene id: 106370:FRANCCI3_RS04225
uniprot id: Q2JER8
names: Similarity
messages: Belongs to the allantoicase family.

106370:FRANCCI3 RS19910
gene id: 106370:FRANCCI3_RS19910
uniprot id: Q2J5Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

106370:FRANCCI3 RS17700
gene id: 106370:FRANCCI3_RS17700
uniprot id: Q2J782
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

106370:FRANCCI3 RS02405
gene id: 106370:FRANCCI3_RS02405
uniprot id: Q2JFS4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

106370:FRANCCI3 RS00460
gene id: 106370:FRANCCI3_RS00460
uniprot id: Q2JGV4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

106370:FRANCCI3 RS00400
gene id: 106370:FRANCCI3_RS00400
uniprot id: Q2JGW6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS17835
gene id: 106370:FRANCCI3_RS17835
uniprot id: Q2J755
names: Similarity
messages: Belongs to the PspA/IM30 family.

106370:FRANCCI3 RS19755
gene id: 106370:FRANCCI3_RS19755
uniprot id: A0A1X1PUW5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS18595
gene id: 106370:FRANCCI3_RS18595
uniprot id: Q2J6R0
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

106370:FRANCCI3 RS18125
gene id: 106370:FRANCCI3_RS18125
uniprot id: Q2J6Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

106370:FRANCCI3 RS01105
gene id: 106370:FRANCCI3_RS01105
uniprot id: A0A1X1PZN0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS20270
gene id: 106370:FRANCCI3_RS20270
uniprot id: Q2J5T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

106370:FRANCCI3 RS17245
gene id: 106370:FRANCCI3_RS17245
uniprot id: A0A1X1Q0V5
uniprot id: Q2J7H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum
messages: Involved in sporulation-specific cell division.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS16005
gene id: 106370:FRANCCI3_RS16005
uniprot id: Q2J854
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

106370:FRANCCI3 RS00735
gene id: 106370:FRANCCI3_RS00735
uniprot id: Q2JGQ1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

106370:FRANCCI3 RS02875
gene id: 106370:FRANCCI3_RS02875
uniprot id: A0A1X1PQV0
uniprot id: Q2JFI6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS13460
gene id: 106370:FRANCCI3_RS13460
uniprot id: A0A1X1PVN5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS09360
gene id: 106370:FRANCCI3_RS09360
uniprot id: Q2JBV4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

106370:FRANCCI3 RS03155
gene id: 106370:FRANCCI3_RS03155
uniprot id: A0A1X1Q1H5
uniprot id: Q2JFC9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS13135
gene id: 106370:FRANCCI3_RS13135
uniprot id: Q2J9S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

106370:FRANCCI3 RS19570
gene id: 106370:FRANCCI3_RS19570
uniprot id: A0A1X1PT82
names: Caution
names: Similarity
messages: Belongs to the FBPase class 2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS18065
gene id: 106370:FRANCCI3_RS18065
uniprot id: Q2J711
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

106370:FRANCCI3 RS06860
gene id: 106370:FRANCCI3_RS06860
uniprot id: Q2JD99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

106370:FRANCCI3 RS03250
gene id: 106370:FRANCCI3_RS03250
uniprot id: Q2JFB1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

106370:FRANCCI3 RS06130
gene id: 106370:FRANCCI3_RS06130
uniprot id: Q2JDP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

106370:FRANCCI3 RS18735
gene id: 106370:FRANCCI3_RS18735
uniprot id: Q2J6N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

106370:FRANCCI3 RS20035
gene id: 106370:FRANCCI3_RS20035
uniprot id: A0A1X1PU44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS08215
gene id: 106370:FRANCCI3_RS08215
uniprot id: Q2JCI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

106370:FRANCCI3 RS01085
gene id: 106370:FRANCCI3_RS01085
uniprot id: Q2JGI7
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

106370:FRANCCI3 RS22160
gene id: 106370:FRANCCI3_RS22160
uniprot id: Q2J4R8
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

106370:FRANCCI3 RS03000
gene id: 106370:FRANCCI3_RS03000
uniprot id: Q2JFG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

106370:FRANCCI3 RS01075
gene id: 106370:FRANCCI3_RS01075
uniprot id: Q2JGI9
names: Similarity
messages: Belongs to the TmoD/XamoD family.

106370:FRANCCI3 RS02430
gene id: 106370:FRANCCI3_RS02430
uniprot id: Q2JFR9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

106370:FRANCCI3 RS12860
gene id: 106370:FRANCCI3_RS12860
uniprot id: Q2J9X3
names: Similarity
messages: Belongs to the YoeB family.

106370:FRANCCI3 RS22780
gene id: 106370:FRANCCI3_RS22780
uniprot id: Q2J4E2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

106370:FRANCCI3 RS08225
gene id: 106370:FRANCCI3_RS08225
uniprot id: Q2JCH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

106370:FRANCCI3 RS21855
gene id: 106370:FRANCCI3_RS21855
uniprot id: Q2J4X5
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

106370:FRANCCI3 RS12515
gene id: 106370:FRANCCI3_RS12515
uniprot id: Q2JA33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

106370:FRANCCI3 RS09635
gene id: 106370:FRANCCI3_RS09635
uniprot id: Q2JBP8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

106370:FRANCCI3 RS02275
gene id: 106370:FRANCCI3_RS02275
uniprot id: A0A1X1PUR5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS10225
gene id: 106370:FRANCCI3_RS10225
uniprot id: A0A1X1PTV8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS06660
gene id: 106370:FRANCCI3_RS06660
uniprot id: Q2JDD5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

106370:FRANCCI3 RS03715
gene id: 106370:FRANCCI3_RS03715
uniprot id: A0A1X1Q2T2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS12200
gene id: 106370:FRANCCI3_RS12200
uniprot id: Q2JA99
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

106370:FRANCCI3 RS21535
gene id: 106370:FRANCCI3_RS21535
uniprot id: Q2J536
names: Similarity
messages: Belongs to the Nth/MutY family.

106370:FRANCCI3 RS13440
gene id: 106370:FRANCCI3_RS13440
uniprot id: Q2J9L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

106370:FRANCCI3 RS15960
gene id: 106370:FRANCCI3_RS15960
uniprot id: Q2J863
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

106370:FRANCCI3 RS05365
gene id: 106370:FRANCCI3_RS05365
uniprot id: Q2JE39
names: Similarity
messages: Belongs to the HupF/HypC family.

106370:FRANCCI3 RS09730
gene id: 106370:FRANCCI3_RS09730
uniprot id: Q2JBN0
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

106370:FRANCCI3 RS18120
gene id: 106370:FRANCCI3_RS18120
uniprot id: Q2J700
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

106370:FRANCCI3 RS19225
gene id: 106370:FRANCCI3_RS19225
uniprot id: A0A1X1PRJ7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS12550
gene id: 106370:FRANCCI3_RS12550
uniprot id: Q2JA26
names: Similarity
messages: Belongs to the SCO1/2 family.

106370:FRANCCI3 RS18200
gene id: 106370:FRANCCI3_RS18200
uniprot id: Q2J6Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

106370:FRANCCI3 RS17895
gene id: 106370:FRANCCI3_RS17895
uniprot id: Q2J744
names: Similarity
messages: Belongs to the XFP family.

106370:FRANCCI3 RS04360
gene id: 106370:FRANCCI3_RS04360
uniprot id: Q2JEN9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

106370:FRANCCI3 RS22250
gene id: 106370:FRANCCI3_RS22250
uniprot id: Q2J4P9
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

106370:FRANCCI3 RS17990
gene id: 106370:FRANCCI3_RS17990
uniprot id: Q2J726
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

106370:FRANCCI3 RS04855
gene id: 106370:FRANCCI3_RS04855
uniprot id: Q2JED8
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

106370:FRANCCI3 RS05670
gene id: 106370:FRANCCI3_RS05670
uniprot id: Q2JDX8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

106370:FRANCCI3 RS15215
gene id: 106370:FRANCCI3_RS15215
uniprot id: A0A1X1PV34
uniprot id: Q2J8K9
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS16090
gene id: 106370:FRANCCI3_RS16090
uniprot id: Q2J838
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

106370:FRANCCI3 RS07975
gene id: 106370:FRANCCI3_RS07975
uniprot id: A0A1X1Q2N0
names: Caution
names: Similarity
messages: Belongs to the HSP15 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS21935
gene id: 106370:FRANCCI3_RS21935
uniprot id: Q2J4V9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

106370:FRANCCI3 RS17845
gene id: 106370:FRANCCI3_RS17845
uniprot id: Q2J754
names: Similarity
messages: Belongs to the Dps family.

106370:FRANCCI3 RS03030
gene id: 106370:FRANCCI3_RS03030
uniprot id: Q2JFF5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

106370:FRANCCI3 RS08285
gene id: 106370:FRANCCI3_RS08285
uniprot id: Q2JCG7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

106370:FRANCCI3 RS03860
gene id: 106370:FRANCCI3_RS03860
uniprot id: Q2JEZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

106370:FRANCCI3 RS19835
gene id: 106370:FRANCCI3_RS19835
uniprot id: Q2J611
names: Cofactor
messages: Binds 1 zinc ion per subunit.

106370:FRANCCI3 RS11985
gene id: 106370:FRANCCI3_RS11985
uniprot id: Q2JAE0
names: Similarity
messages: Belongs to the HAM1 NTPase family.

106370:FRANCCI3 RS12010
gene id: 106370:FRANCCI3_RS12010
uniprot id: Q2JAD5
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS04085
gene id: 106370:FRANCCI3_RS04085
uniprot id: Q2JEU5
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS10115
gene id: 106370:FRANCCI3_RS10115
uniprot id: Q2JBF4
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS18785
gene id: 106370:FRANCCI3_RS18785
uniprot id: Q2J6M1
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

106370:FRANCCI3 RS21530
gene id: 106370:FRANCCI3_RS21530
uniprot id: Q2J537
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

106370:FRANCCI3 RS16200
gene id: 106370:FRANCCI3_RS16200
uniprot id: Q2J816
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

106370:FRANCCI3 RS04005
gene id: 106370:FRANCCI3_RS04005
uniprot id: A0A1X1PRW7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS06295
gene id: 106370:FRANCCI3_RS06295
uniprot id: Q2JDK8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

106370:FRANCCI3 RS03195
gene id: 106370:FRANCCI3_RS03195
uniprot id: Q2JFC1
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

106370:FRANCCI3 RS17580
gene id: 106370:FRANCCI3_RS17580
uniprot id: Q2J7A6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

106370:FRANCCI3 RS10090
gene id: 106370:FRANCCI3_RS10090
uniprot id: Q2JBF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

106370:FRANCCI3 RS18755
gene id: 106370:FRANCCI3_RS18755
uniprot id: A0A1X1PSM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS11565
gene id: 106370:FRANCCI3_RS11565
uniprot id: A0A1X1PS11
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS22960
gene id: 106370:FRANCCI3_RS22960
uniprot id: Q2J4B0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

106370:FRANCCI3 RS04580
gene id: 106370:FRANCCI3_RS04580
uniprot id: Q2JEJ3
names: Similarity
messages: Belongs to the SCO1/2 family.

106370:FRANCCI3 RS10540
gene id: 106370:FRANCCI3_RS10540
uniprot id: Q2JB76
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

106370:FRANCCI3 RS19400
gene id: 106370:FRANCCI3_RS19400
uniprot id: Q2J6A2
names: Similarity
messages: Belongs to the LOG family.

106370:FRANCCI3 RS07575
gene id: 106370:FRANCCI3_RS07575
uniprot id: A0A1X1Q0J6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS02660
gene id: 106370:FRANCCI3_RS02660
uniprot id: Q2JFM5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

106370:FRANCCI3 RS18145
gene id: 106370:FRANCCI3_RS18145
uniprot id: Q2J6Z5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

106370:FRANCCI3 RS18750
gene id: 106370:FRANCCI3_RS18750
uniprot id: Q2J6M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

106370:FRANCCI3 RS02425
gene id: 106370:FRANCCI3_RS02425
uniprot id: Q2JFS0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

106370:FRANCCI3 RS02715
gene id: 106370:FRANCCI3_RS02715
uniprot id: Q2JFL4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

106370:FRANCCI3 RS04610
gene id: 106370:FRANCCI3_RS04610
uniprot id: A0A1X1PTB3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

106370:FRANCCI3 RS10030
gene id: 106370:FRANCCI3_RS10030
uniprot id: Q2JBH1
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS21890
gene id: 106370:FRANCCI3_RS21890
uniprot id: A0A1X1PX36
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS18370
gene id: 106370:FRANCCI3_RS18370
uniprot id: A0A1X1PXK8
uniprot id: Q2J6V2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS11200
gene id: 106370:FRANCCI3_RS11200
uniprot id: Q2JAU4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

106370:FRANCCI3 RS04220
gene id: 106370:FRANCCI3_RS04220
uniprot id: Q2JER9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.

106370:FRANCCI3 RS09780
gene id: 106370:FRANCCI3_RS09780
uniprot id: Q2JBM1
names: Similarity
messages: Belongs to the HupF/HypC family.

106370:FRANCCI3 RS18265
gene id: 106370:FRANCCI3_RS18265
uniprot id: Q2J6X1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

106370:FRANCCI3 RS02210
gene id: 106370:FRANCCI3_RS02210
uniprot id: A0A1X1PVB0
names: Caution
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS15110
gene id: 106370:FRANCCI3_RS15110
uniprot id: Q2J8N0
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

106370:FRANCCI3 RS21750
gene id: 106370:FRANCCI3_RS21750
uniprot id: Q2J4Z4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

106370:FRANCCI3 RS01410
gene id: 106370:FRANCCI3_RS01410
uniprot id: A0A1X1PU05
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS11300
gene id: 106370:FRANCCI3_RS11300
uniprot id: Q2JAS4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

106370:FRANCCI3 RS22980
gene id: 106370:FRANCCI3_RS22980
uniprot id: Q2J4A6
names: Similarity
messages: Belongs to the ParB family.

106370:FRANCCI3 RS16170
gene id: 106370:FRANCCI3_RS16170
uniprot id: Q2J822
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

106370:FRANCCI3 RS18490
gene id: 106370:FRANCCI3_RS18490
uniprot id: Q2J6T1
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

106370:FRANCCI3 RS04105
gene id: 106370:FRANCCI3_RS04105
uniprot id: Q2JEU2
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS22610
gene id: 106370:FRANCCI3_RS22610
uniprot id: Q2J4H7
names: Subcellular Location Annotation
messages: Cytoplasm

106370:FRANCCI3 RS17025
gene id: 106370:FRANCCI3_RS17025
uniprot id: Q2J7K7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS06685
gene id: 106370:FRANCCI3_RS06685
uniprot id: Q2JDD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

106370:FRANCCI3 RS06665
gene id: 106370:FRANCCI3_RS06665
uniprot id: A0A1X1PYG5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS02265
gene id: 106370:FRANCCI3_RS02265
uniprot id: Q2JFV4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
messages: Homodimer.

106370:FRANCCI3 RS14265
gene id: 106370:FRANCCI3_RS14265
uniprot id: Q2J946
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

106370:FRANCCI3 RS10035
gene id: 106370:FRANCCI3_RS10035
uniprot id: Q2JBH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

106370:FRANCCI3 RS02855
gene id: 106370:FRANCCI3_RS02855
uniprot id: Q2JFJ0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

106370:FRANCCI3 RS19605
gene id: 106370:FRANCCI3_RS19605
uniprot id: Q2J659
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

106370:FRANCCI3 RS18185
gene id: 106370:FRANCCI3_RS18185
uniprot id: Q2J6Y8
names: Subcellular Location Annotation
messages: Cytoplasm

106370:FRANCCI3 RS02665
gene id: 106370:FRANCCI3_RS02665
uniprot id: Q2JFM4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

106370:FRANCCI3 RS06155
gene id: 106370:FRANCCI3_RS06155
uniprot id: Q2JDN6
names: Similarity
messages: Belongs to the malate synthase family.

106370:FRANCCI3 RS02720
gene id: 106370:FRANCCI3_RS02720
uniprot id: Q2JFL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

106370:FRANCCI3 RS22990
gene id: 106370:FRANCCI3_RS22990
uniprot id: Q2J4A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 518 of 16S rRNA.

106370:FRANCCI3 RS15505
gene id: 106370:FRANCCI3_RS15505
uniprot id: Q2J8F0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

106370:FRANCCI3 RS08205
gene id: 106370:FRANCCI3_RS08205
uniprot id: Q2JCI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

106370:FRANCCI3 RS06385
gene id: 106370:FRANCCI3_RS06385
uniprot id: Q2JDJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

106370:FRANCCI3 RS00740
gene id: 106370:FRANCCI3_RS00740
uniprot id: Q2JGQ0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

106370:FRANCCI3 RS21635
gene id: 106370:FRANCCI3_RS21635
uniprot id: Q2J518
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

106370:FRANCCI3 RS07130
gene id: 106370:FRANCCI3_RS07130
uniprot id: Q2JD47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

106370:FRANCCI3 RS07440
gene id: 106370:FRANCCI3_RS07440
uniprot id: A0A1X1PQU4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS14825
gene id: 106370:FRANCCI3_RS14825
uniprot id: Q2J8T5
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

106370:FRANCCI3 RS06765
gene id: 106370:FRANCCI3_RS06765
uniprot id: Q2JDB4
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS07135
gene id: 106370:FRANCCI3_RS07135
uniprot id: Q2JD46
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

106370:FRANCCI3 RS03065
gene id: 106370:FRANCCI3_RS03065
uniprot id: A0A1X1Q1C4
uniprot id: Q2JFE7
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS03410
gene id: 106370:FRANCCI3_RS03410
uniprot id: Q2JF80
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

106370:FRANCCI3 RS10835
gene id: 106370:FRANCCI3_RS10835
uniprot id: Q2JB14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
messages: Cell membrane
messages: Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PhnC), two transmembrane proteins (PhnE) and a solute-binding protein (PhnD).

106370:FRANCCI3 RS15980
gene id: 106370:FRANCCI3_RS15980
uniprot id: Q2J859
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

106370:FRANCCI3 RS18545
gene id: 106370:FRANCCI3_RS18545
uniprot id: A0A1X1Q130
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS08280
gene id: 106370:FRANCCI3_RS08280
uniprot id: Q2JCG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

106370:FRANCCI3 RS02285
gene id: 106370:FRANCCI3_RS02285
uniprot id: Q2JFV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

106370:FRANCCI3 RS25305
gene id: 106370:FRANCCI3_RS25305
uniprot id: A0A1X1Q063
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS12300
gene id: 106370:FRANCCI3_RS12300
uniprot id: Q2JA78
names: Similarity
messages: Belongs to the ABC transporter superfamily.

106370:FRANCCI3 RS02385
gene id: 106370:FRANCCI3_RS02385
uniprot id: Q2JFS8
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

106370:FRANCCI3 RS11210
gene id: 106370:FRANCCI3_RS11210
uniprot id: Q2JAU2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

106370:FRANCCI3 RS00835
gene id: 106370:FRANCCI3_RS00835
uniprot id: Q2JGN3
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

106370:FRANCCI3 RS18075
gene id: 106370:FRANCCI3_RS18075
uniprot id: Q2J709
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

106370:FRANCCI3 RS05275
gene id: 106370:FRANCCI3_RS05275
uniprot id: Q2JE57
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS15115
gene id: 106370:FRANCCI3_RS15115
uniprot id: Q2J8M9
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

106370:FRANCCI3 RS04000
gene id: 106370:FRANCCI3_RS04000
uniprot id: Q2JEW2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

106370:FRANCCI3 RS15675
gene id: 106370:FRANCCI3_RS15675
uniprot id: A0A1X1PS82
names: Caution
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS02915
gene id: 106370:FRANCCI3_RS02915
uniprot id: Q2JFH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

106370:FRANCCI3 RS08755
gene id: 106370:FRANCCI3_RS08755
uniprot id: Q2JC80
names: Similarity
messages: Belongs to the GSP E family.

106370:FRANCCI3 RS19520
gene id: 106370:FRANCCI3_RS19520
uniprot id: Q2J676
names: Similarity
messages: Belongs to the Nudix hydrolase family.

106370:FRANCCI3 RS15205
gene id: 106370:FRANCCI3_RS15205
uniprot id: Q2J8L1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

106370:FRANCCI3 RS04655
gene id: 106370:FRANCCI3_RS04655
uniprot id: Q2JEH8
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

106370:FRANCCI3 RS05305
gene id: 106370:FRANCCI3_RS05305
uniprot id: Q2JE51
names: Similarity
messages: Belongs to the glutathione peroxidase family.

106370:FRANCCI3 RS22695
gene id: 106370:FRANCCI3_RS22695
uniprot id: Q2J4G0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

106370:FRANCCI3 RS18660
gene id: 106370:FRANCCI3_RS18660
uniprot id: Q2J6P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

106370:FRANCCI3 RS07110
gene id: 106370:FRANCCI3_RS07110
uniprot id: Q2JD51
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS02440
gene id: 106370:FRANCCI3_RS02440
uniprot id: Q2JFR7
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS15965
gene id: 106370:FRANCCI3_RS15965
uniprot id: Q2J862
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

106370:FRANCCI3 RS21930
gene id: 106370:FRANCCI3_RS21930
uniprot id: Q2J4W0
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

106370:FRANCCI3 RS01870
gene id: 106370:FRANCCI3_RS01870
uniprot id: Q2JG27
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS00765
gene id: 106370:FRANCCI3_RS00765
uniprot id: Q2JGP5
names: Similarity
messages: Belongs to the HepT RNase toxin family.

106370:FRANCCI3 RS10010
gene id: 106370:FRANCCI3_RS10010
uniprot id: Q2JBH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

106370:FRANCCI3 RS17175
gene id: 106370:FRANCCI3_RS17175
uniprot id: Q2J7I2
names: Similarity
messages: Belongs to the AAA ATPase family.

106370:FRANCCI3 RS13650
gene id: 106370:FRANCCI3_RS13650
uniprot id: Q2J9H0
names: Similarity
messages: Belongs to the group II decarboxylase family.

106370:FRANCCI3 RS12710
gene id: 106370:FRANCCI3_RS12710
uniprot id: Q2J9Z9
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

106370:FRANCCI3 RS07370
gene id: 106370:FRANCCI3_RS07370
uniprot id: Q2JD00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

106370:FRANCCI3 RS11005
gene id: 106370:FRANCCI3_RS11005
uniprot id: Q2JAY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

106370:FRANCCI3 RS00135
gene id: 106370:FRANCCI3_RS00135
uniprot id: Q2JH20
names: Similarity
messages: Belongs to the OsmC/Ohr family.

106370:FRANCCI3 RS03790
gene id: 106370:FRANCCI3_RS03790
uniprot id: Q2JF05
names: Similarity
messages: Belongs to the PGI/PMI family.

106370:FRANCCI3 RS09465
gene id: 106370:FRANCCI3_RS09465
uniprot id: Q2JBT2
names: Similarity
messages: Belongs to the HepT RNase toxin family.

106370:FRANCCI3 RS09640
gene id: 106370:FRANCCI3_RS09640
uniprot id: Q2JBP7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

106370:FRANCCI3 RS06875
gene id: 106370:FRANCCI3_RS06875
uniprot id: Q2JD96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

106370:FRANCCI3 RS02105
gene id: 106370:FRANCCI3_RS02105
uniprot id: Q2JFY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

106370:FRANCCI3 RS19345
gene id: 106370:FRANCCI3_RS19345
uniprot id: Q2J6B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

106370:FRANCCI3 RS19195
gene id: 106370:FRANCCI3_RS19195
uniprot id: Q2J6E2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

106370:FRANCCI3 RS15800
gene id: 106370:FRANCCI3_RS15800
uniprot id: Q2J892
names: Similarity
messages: Belongs to the glutamine synthetase family.

106370:FRANCCI3 RS15150
gene id: 106370:FRANCCI3_RS15150
uniprot id: Q2J8M2
names: Similarity
messages: Belongs to the glutamate synthase family.

106370:FRANCCI3 RS03035
gene id: 106370:FRANCCI3_RS03035
uniprot id: Q2JFF4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

106370:FRANCCI3 RS02635
gene id: 106370:FRANCCI3_RS02635
uniprot id: Q2JFN0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

106370:FRANCCI3 RS02725
gene id: 106370:FRANCCI3_RS02725
uniprot id: Q2JFL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

106370:FRANCCI3 RS12070
gene id: 106370:FRANCCI3_RS12070
uniprot id: Q2JAC3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane

106370:FRANCCI3 RS05435
gene id: 106370:FRANCCI3_RS05435
uniprot id: Q2JE25
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

106370:FRANCCI3 RS03275
gene id: 106370:FRANCCI3_RS03275
uniprot id: Q2JFA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

106370:FRANCCI3 RS02685
gene id: 106370:FRANCCI3_RS02685
uniprot id: Q2JFM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

106370:FRANCCI3 RS22775
gene id: 106370:FRANCCI3_RS22775
uniprot id: Q2J4E3
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS08050
gene id: 106370:FRANCCI3_RS08050
uniprot id: Q2JCL3
names: Similarity
messages: Belongs to the thioesterase family.

106370:FRANCCI3 RS09645
gene id: 106370:FRANCCI3_RS09645
uniprot id: Q2JBP6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

106370:FRANCCI3 RS00025
gene id: 106370:FRANCCI3_RS00025
uniprot id: Q2JH44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

106370:FRANCCI3 RS20400
gene id: 106370:FRANCCI3_RS20400
uniprot id: Q2J5Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

106370:FRANCCI3 RS23375
gene id: 106370:FRANCCI3_RS23375
uniprot id: Q2JBC6
names: Similarity
messages: Belongs to the cytochrome P450 family.

106370:FRANCCI3 RS16530
gene id: 106370:FRANCCI3_RS16530
uniprot id: A0A1X1PX11
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS22565
gene id: 106370:FRANCCI3_RS22565
uniprot id: Q2J4I8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

106370:FRANCCI3 RS03130
gene id: 106370:FRANCCI3_RS03130
uniprot id: Q2JFD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS17715
gene id: 106370:FRANCCI3_RS17715
uniprot id: A0A1X1PWB2
uniprot id: Q2J779
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS16975
gene id: 106370:FRANCCI3_RS16975
uniprot id: Q2J7L8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

106370:FRANCCI3 RS27245
gene id: 106370:FRANCCI3_RS27245
uniprot id: Q2JFY2
names: Similarity
messages: Belongs to the peptidase C40 family.

106370:FRANCCI3 RS09735
gene id: 106370:FRANCCI3_RS09735
uniprot id: Q2JBM9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

106370:FRANCCI3 RS02810
gene id: 106370:FRANCCI3_RS02810
uniprot id: Q2JFJ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

106370:FRANCCI3 RS19405
gene id: 106370:FRANCCI3_RS19405
uniprot id: Q2J6A1
names: Similarity
messages: Belongs to the LOG family.

106370:FRANCCI3 RS14070
gene id: 106370:FRANCCI3_RS14070
uniprot id: Q2J987
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane

106370:FRANCCI3 RS23620
gene id: 106370:FRANCCI3_RS23620
uniprot id: Q2J7K5
names: Similarity
messages: Belongs to the methyltransferase superfamily. Aminoglycoside resistance family.

106370:FRANCCI3 RS09770
gene id: 106370:FRANCCI3_RS09770
uniprot id: A0A1X1PXQ9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS28075
gene id: 106370:FRANCCI3_RS28075
uniprot id: Q2JAA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

106370:FRANCCI3 RS17470
gene id: 106370:FRANCCI3_RS17470
uniprot id: Q2J7C8
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme modulates the balance between respiration and glycolysis, and contributes to redox homeostasis. Probably eliminates toxic levels of Cys (which can induce oxidative stress).
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

106370:FRANCCI3 RS18035
gene id: 106370:FRANCCI3_RS18035
uniprot id: Q2J717
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

106370:FRANCCI3 RS23995
gene id: 106370:FRANCCI3_RS23995
uniprot id: A0A1X1Q1E2
uniprot id: Q2JFF2
names: Caution
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS17880
gene id: 106370:FRANCCI3_RS17880
uniprot id: Q2J747
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

106370:FRANCCI3 RS13425
gene id: 106370:FRANCCI3_RS13425
uniprot id: A0A1X1PVL4
uniprot id: Q2J9L7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS19055
gene id: 106370:FRANCCI3_RS19055
uniprot id: Q2J6G9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

106370:FRANCCI3 RS04195
gene id: 106370:FRANCCI3_RS04195
uniprot id: A0A1X1PYD0
uniprot id: Q2JES4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS06990
gene id: 106370:FRANCCI3_RS06990
uniprot id: A0A1X1Q1A3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS06820
gene id: 106370:FRANCCI3_RS06820
uniprot id: Q2JDA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SsgA family.
messages: Cell septum
messages: Interacts with SsgA. Interacts with FtsZ (via N-terminus).
messages: Involved in sporulation-specific cell division (PubMed:19567872). Required for early stages of sporulation. Important in the process of growth cessation prior to sporulation-specific cell division. Recruits cell division protein FtsZ to the future septum sites and tethers the contractile ring structure (Z ring) to the cytoplasmic membrane during sporulation. Stimulates polymerization and filament length of FtsZ in vitro (By similarity).

106370:FRANCCI3 RS12170
gene id: 106370:FRANCCI3_RS12170
uniprot id: Q2JAA5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

106370:FRANCCI3 RS04940
gene id: 106370:FRANCCI3_RS04940
uniprot id: A0A1X1PV90
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS16780
gene id: 106370:FRANCCI3_RS16780
uniprot id: Q2J7Q3
names: Similarity
messages: Belongs to the GSP E family.

106370:FRANCCI3 RS15160
gene id: 106370:FRANCCI3_RS15160
uniprot id: Q2J8M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

106370:FRANCCI3 RS14505
gene id: 106370:FRANCCI3_RS14505
uniprot id: Q2J8Z9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

106370:FRANCCI3 RS15250
gene id: 106370:FRANCCI3_RS15250
uniprot id: Q2J8K2
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

106370:FRANCCI3 RS04880
gene id: 106370:FRANCCI3_RS04880
uniprot id: Q2JED3
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

106370:FRANCCI3 RS13560
gene id: 106370:FRANCCI3_RS13560
uniprot id: Q2J9J0
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS08340
gene id: 106370:FRANCCI3_RS08340
uniprot id: Q2JCF6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

106370:FRANCCI3 RS12305
gene id: 106370:FRANCCI3_RS12305
uniprot id: Q2JA77
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS03920
gene id: 106370:FRANCCI3_RS03920
uniprot id: Q2JEX9
names: Similarity
messages: Belongs to the GSP E family.

106370:FRANCCI3 RS21555
gene id: 106370:FRANCCI3_RS21555
uniprot id: Q2J532
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

106370:FRANCCI3 RS11085
gene id: 106370:FRANCCI3_RS11085
uniprot id: A0A1X1PW50
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS19815
gene id: 106370:FRANCCI3_RS19815
uniprot id: A0A1X1Q008
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS05900
gene id: 106370:FRANCCI3_RS05900
uniprot id: Q2JDT4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

106370:FRANCCI3 RS10830
gene id: 106370:FRANCCI3_RS10830
uniprot id: Q2JB15
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

106370:FRANCCI3 RS18925
gene id: 106370:FRANCCI3_RS18925
uniprot id: Q2J6J4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

106370:FRANCCI3 RS05035
gene id: 106370:FRANCCI3_RS05035
uniprot id: Q2JEA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

106370:FRANCCI3 RS01745
gene id: 106370:FRANCCI3_RS01745
uniprot id: Q2JG54
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

106370:FRANCCI3 RS03640
gene id: 106370:FRANCCI3_RS03640
uniprot id: Q2JF34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

106370:FRANCCI3 RS03925
gene id: 106370:FRANCCI3_RS03925
uniprot id: Q2JEX8
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS06335
gene id: 106370:FRANCCI3_RS06335
uniprot id: Q2JDK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

106370:FRANCCI3 RS12490
gene id: 106370:FRANCCI3_RS12490
uniprot id: Q2JA39
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

106370:FRANCCI3 RS21460
gene id: 106370:FRANCCI3_RS21460
uniprot id: Q2J552
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

106370:FRANCCI3 RS15955
gene id: 106370:FRANCCI3_RS15955
uniprot id: Q2J864
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

106370:FRANCCI3 RS18585
gene id: 106370:FRANCCI3_RS18585
uniprot id: Q2J6R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

106370:FRANCCI3 RS15885
gene id: 106370:FRANCCI3_RS15885
uniprot id: Q2J875
names: Similarity
messages: Belongs to the TlyA family.

106370:FRANCCI3 RS18730
gene id: 106370:FRANCCI3_RS18730
uniprot id: A0A1X1Q161
uniprot id: Q2J6N2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS22095
gene id: 106370:FRANCCI3_RS22095
uniprot id: Q2J4T0
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

106370:FRANCCI3 RS02995
gene id: 106370:FRANCCI3_RS02995
uniprot id: A0A1X1Q1B4
uniprot id: Q2JFG2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS02615
gene id: 106370:FRANCCI3_RS02615
uniprot id: A0A1X1PUC1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS07180
gene id: 106370:FRANCCI3_RS07180
uniprot id: A0A1X1PWG6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS20435
gene id: 106370:FRANCCI3_RS20435
uniprot id: Q2J5P7
names: Similarity
messages: Belongs to the CsoR family.

106370:FRANCCI3 RS02920
gene id: 106370:FRANCCI3_RS02920
uniprot id: Q2JFH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

106370:FRANCCI3 RS08450
gene id: 106370:FRANCCI3_RS08450
uniprot id: Q2JCD5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

106370:FRANCCI3 RS18155
gene id: 106370:FRANCCI3_RS18155
uniprot id: Q2J6Z3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

106370:FRANCCI3 RS02960
gene id: 106370:FRANCCI3_RS02960
uniprot id: A0A1X1PQQ8
uniprot id: Q2JFG9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS19330
gene id: 106370:FRANCCI3_RS19330
uniprot id: Q2J6B7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

106370:FRANCCI3 RS02695
gene id: 106370:FRANCCI3_RS02695
uniprot id: Q2JFL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

106370:FRANCCI3 RS01845
gene id: 106370:FRANCCI3_RS01845
uniprot id: Q2JG31
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

106370:FRANCCI3 RS02750
gene id: 106370:FRANCCI3_RS02750
uniprot id: Q2JFK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

106370:FRANCCI3 RS18230
gene id: 106370:FRANCCI3_RS18230
uniprot id: Q2J6X8
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

106370:FRANCCI3 RS06370
gene id: 106370:FRANCCI3_RS06370
uniprot id: A0A1X1PUE9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS27235
gene id: 106370:FRANCCI3_RS27235
uniprot id: A0A1X1PYU9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS22640
gene id: 106370:FRANCCI3_RS22640
uniprot id: Q2J4H1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

106370:FRANCCI3 RS04155
gene id: 106370:FRANCCI3_RS04155
uniprot id: Q2JET2
names: Similarity
messages: Belongs to the thioesterase PaaI family.

106370:FRANCCI3 RS19110
gene id: 106370:FRANCCI3_RS19110
uniprot id: Q2J6F8
names: Similarity
messages: Belongs to the peptidase S16 family.

106370:FRANCCI3 RS07485
gene id: 106370:FRANCCI3_RS07485
uniprot id: Q2JCX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

106370:FRANCCI3 RS02930
gene id: 106370:FRANCCI3_RS02930
uniprot id: A0A1X1PSZ5
uniprot id: Q2JFH5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS02630
gene id: 106370:FRANCCI3_RS02630
uniprot id: Q2JFN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

106370:FRANCCI3 RS17755
gene id: 106370:FRANCCI3_RS17755
uniprot id: Q2J771
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

106370:FRANCCI3 RS18060
gene id: 106370:FRANCCI3_RS18060
uniprot id: Q2J712
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

106370:FRANCCI3 RS13280
gene id: 106370:FRANCCI3_RS13280
uniprot id: Q2J9P4
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS00385
gene id: 106370:FRANCCI3_RS00385
uniprot id: A0A1X1PVK3
uniprot id: Q2JGW9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS10925
gene id: 106370:FRANCCI3_RS10925
uniprot id: Q2JAZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

106370:FRANCCI3 RS05875
gene id: 106370:FRANCCI3_RS05875
uniprot id: Q2JDT9
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS00040
gene id: 106370:FRANCCI3_RS00040
uniprot id: Q2JH41
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

106370:FRANCCI3 RS15750
gene id: 106370:FRANCCI3_RS15750
uniprot id: Q2J8A2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

106370:FRANCCI3 RS03080
gene id: 106370:FRANCCI3_RS03080
uniprot id: Q2JFE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

106370:FRANCCI3 RS20030
gene id: 106370:FRANCCI3_RS20030
uniprot id: A0A1X1PU30
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS01135
gene id: 106370:FRANCCI3_RS01135
uniprot id: Q2JGH8
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

106370:FRANCCI3 RS01320
gene id: 106370:FRANCCI3_RS01320
uniprot id: Q2JGE0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

106370:FRANCCI3 RS01160
gene id: 106370:FRANCCI3_RS01160
uniprot id: Q2JGH2
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS12250
gene id: 106370:FRANCCI3_RS12250
uniprot id: Q2JA89
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

106370:FRANCCI3 RS00070
gene id: 106370:FRANCCI3_RS00070
uniprot id: A0A1X1PVA1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS12565
gene id: 106370:FRANCCI3_RS12565
uniprot id: Q2JA23
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

106370:FRANCCI3 RS05370
gene id: 106370:FRANCCI3_RS05370
uniprot id: Q2JE38
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

106370:FRANCCI3 RS02870
gene id: 106370:FRANCCI3_RS02870
uniprot id: Q2JFI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

106370:FRANCCI3 RS08530
gene id: 106370:FRANCCI3_RS08530
uniprot id: Q2JCC0
names: Similarity
messages: Belongs to the peptidase C40 family.

106370:FRANCCI3 RS18070
gene id: 106370:FRANCCI3_RS18070
uniprot id: Q2J710
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

106370:FRANCCI3 RS03485
gene id: 106370:FRANCCI3_RS03485
uniprot id: Q2JF66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

106370:FRANCCI3 RS18040
gene id: 106370:FRANCCI3_RS18040
uniprot id: Q2J716
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

106370:FRANCCI3 RS02940
gene id: 106370:FRANCCI3_RS02940
uniprot id: Q2JFH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

106370:FRANCCI3 RS12895
gene id: 106370:FRANCCI3_RS12895
uniprot id: Q2J9W6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

106370:FRANCCI3 RS07275
gene id: 106370:FRANCCI3_RS07275
uniprot id: Q2JD18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

106370:FRANCCI3 RS14770
gene id: 106370:FRANCCI3_RS14770
uniprot id: Q2J8U6
names: Subcellular Location Annotation
messages: Membrane

106370:FRANCCI3 RS02950
gene id: 106370:FRANCCI3_RS02950
uniprot id: Q2JFH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

106370:FRANCCI3 RS06545
gene id: 106370:FRANCCI3_RS06545
uniprot id: Q2JDF8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS09745
gene id: 106370:FRANCCI3_RS09745
uniprot id: Q2JBM7
names: Similarity
messages: Belongs to the peptidase A31 family.

106370:FRANCCI3 RS18140
gene id: 106370:FRANCCI3_RS18140
uniprot id: A0A1X1PT83
uniprot id: Q2J6Z6
names: Caution
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS18365
gene id: 106370:FRANCCI3_RS18365
uniprot id: Q2J6V3
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

106370:FRANCCI3 RS06600
gene id: 106370:FRANCCI3_RS06600
uniprot id: Q2JDE7
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

106370:FRANCCI3 RS05660
gene id: 106370:FRANCCI3_RS05660
uniprot id: A0A1X1PU38
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS03055
gene id: 106370:FRANCCI3_RS03055
uniprot id: Q2JFE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

106370:FRANCCI3 RS03040
gene id: 106370:FRANCCI3_RS03040
uniprot id: A0A1X1Q1F2
uniprot id: Q2JFF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS22875
gene id: 106370:FRANCCI3_RS22875
uniprot id: Q2J4C5
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS07635
gene id: 106370:FRANCCI3_RS07635
uniprot id: Q2JCU5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

106370:FRANCCI3 RS07125
gene id: 106370:FRANCCI3_RS07125
uniprot id: Q2JD48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

106370:FRANCCI3 RS14170
gene id: 106370:FRANCCI3_RS14170
uniprot id: Q2J966
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

106370:FRANCCI3 RS00015
gene id: 106370:FRANCCI3_RS00015
uniprot id: Q2JH46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

106370:FRANCCI3 RS19410
gene id: 106370:FRANCCI3_RS19410
uniprot id: Q2J6A0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

106370:FRANCCI3 RS18340
gene id: 106370:FRANCCI3_RS18340
uniprot id: Q2J6V8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

106370:FRANCCI3 RS20715
gene id: 106370:FRANCCI3_RS20715
uniprot id: Q2J5J4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

106370:FRANCCI3 RS13495
gene id: 106370:FRANCCI3_RS13495
uniprot id: Q2J9K2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

106370:FRANCCI3 RS16865
gene id: 106370:FRANCCI3_RS16865
uniprot id: Q2J7N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

106370:FRANCCI3 RS18725
gene id: 106370:FRANCCI3_RS18725
uniprot id: Q2J6N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

106370:FRANCCI3 RS08325
gene id: 106370:FRANCCI3_RS08325
uniprot id: Q2JCF9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

106370:FRANCCI3 RS22965
gene id: 106370:FRANCCI3_RS22965
uniprot id: Q2J4A9
names: Similarity
messages: Belongs to the thioredoxin family.

106370:FRANCCI3 RS11575
gene id: 106370:FRANCCI3_RS11575
uniprot id: A0A1X1PS31
uniprot id: Q2JAL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

106370:FRANCCI3 RS08920
gene id: 106370:FRANCCI3_RS08920
uniprot id: Q2JC46
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

106370:FRANCCI3 RS19880
gene id: 106370:FRANCCI3_RS19880
uniprot id: Q2J602
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

106370:FRANCCI3 RS03140
gene id: 106370:FRANCCI3_RS03140
uniprot id: Q2JFD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

106370:FRANCCI3 RS15295
gene id: 106370:FRANCCI3_RS15295
uniprot id: Q2J8J3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

106370:FRANCCI3 RS15655
gene id: 106370:FRANCCI3_RS15655
uniprot id: Q2J8C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

106370:FRANCCI3 RS20535
gene id: 106370:FRANCCI3_RS20535
uniprot id: Q2J5M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

106370:FRANCCI3 RS21545
gene id: 106370:FRANCCI3_RS21545
uniprot id: Q2J534
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

106370:FRANCCI3 RS03010
gene id: 106370:FRANCCI3_RS03010
uniprot id: Q2JFF9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

106370:FRANCCI3 RS03975
gene id: 106370:FRANCCI3_RS03975
uniprot id: Q2JEW7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.