1050174:CEPID RS06130
gene id: 1050174:CEPID_RS06130
uniprot id: A0A0G3GUD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1050174:CEPID RS10040
gene id: 1050174:CEPID_RS10040
uniprot id: A0A0G3GYH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1050174:CEPID RS00915
gene id: 1050174:CEPID_RS00915
uniprot id: A0A0G3GLN5
names: Similarity
messages: Belongs to the peptidase M13 family.

1050174:CEPID RS07670
gene id: 1050174:CEPID_RS07670
uniprot id: A0A0G3GQM6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1050174:CEPID RS04545
gene id: 1050174:CEPID_RS04545
uniprot id: A0A0G3GNL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1050174:CEPID RS01230
gene id: 1050174:CEPID_RS01230
uniprot id: A0A0G3GRI3
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1050174:CEPID RS02740
gene id: 1050174:CEPID_RS02740
uniprot id: A0A0G3GU98
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS03935
gene id: 1050174:CEPID_RS03935
uniprot id: A0A0G3GQ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1050174:CEPID RS02890
gene id: 1050174:CEPID_RS02890
uniprot id: A0A0G3GPH7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1050174:CEPID RS07105
gene id: 1050174:CEPID_RS07105
uniprot id: A0A0G3GQ99
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1050174:CEPID RS08100
gene id: 1050174:CEPID_RS08100
uniprot id: A0A0G3GSH8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1050174:CEPID RS05235
gene id: 1050174:CEPID_RS05235
uniprot id: A0A0G3GQV4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1050174:CEPID RS07835
gene id: 1050174:CEPID_RS07835
uniprot id: A0A0G3GX71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1050174:CEPID RS03820
gene id: 1050174:CEPID_RS03820
uniprot id: A0A0G3GV15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1050174:CEPID RS08385
gene id: 1050174:CEPID_RS08385
uniprot id: A0A0G3GVL7
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS03900
gene id: 1050174:CEPID_RS03900
uniprot id: A0A0G3GT33
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1050174:CEPID RS12060
gene id: 1050174:CEPID_RS12060
uniprot id: A0A0G3GXQ2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1050174:CEPID RS12140
gene id: 1050174:CEPID_RS12140
uniprot id: A0A0G3GT73
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS02205
gene id: 1050174:CEPID_RS02205
uniprot id: A0A0G3GU07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1050174:CEPID RS00990
gene id: 1050174:CEPID_RS00990
uniprot id: A0A0G3GNF1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1050174:CEPID RS01815
gene id: 1050174:CEPID_RS01815
uniprot id: A0A0G3GRU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1050174:CEPID RS03100
gene id: 1050174:CEPID_RS03100
uniprot id: A0A0G3GMS7
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1050174:CEPID RS02665
gene id: 1050174:CEPID_RS02665
uniprot id: A0A0G3GU90
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1050174:CEPID RS06685
gene id: 1050174:CEPID_RS06685
uniprot id: A0A0G3GPX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1050174:CEPID RS08240
gene id: 1050174:CEPID_RS08240
uniprot id: A0A0G3GVI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1050174:CEPID RS05205
gene id: 1050174:CEPID_RS05205
uniprot id: A0A0G3GP67
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS05225
gene id: 1050174:CEPID_RS05225
uniprot id: A0A0G3GTS1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS08670
gene id: 1050174:CEPID_RS08670
uniprot id: A0A0G3GVW4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1050174:CEPID RS08290
gene id: 1050174:CEPID_RS08290
uniprot id: A0A0G3GR04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1050174:CEPID RS00295
gene id: 1050174:CEPID_RS00295
uniprot id: A0A0G3GLB7
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS03515
gene id: 1050174:CEPID_RS03515
uniprot id: A0A0G3GSW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1050174:CEPID RS10475
gene id: 1050174:CEPID_RS10475
uniprot id: A0A0G3GS20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1050174:CEPID RS06730
gene id: 1050174:CEPID_RS06730
uniprot id: A0A0G3GRR9
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1050174:CEPID RS00770
gene id: 1050174:CEPID_RS00770
uniprot id: A0A0G3GT65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS08720
gene id: 1050174:CEPID_RS08720
uniprot id: A0A0G3GRC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1050174:CEPID RS07735
gene id: 1050174:CEPID_RS07735
uniprot id: A0A0G3GX58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1050174:CEPID RS07485
gene id: 1050174:CEPID_RS07485
uniprot id: A0A0G3GQB6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1050174:CEPID RS07635
gene id: 1050174:CEPID_RS07635
uniprot id: A0A0G3GX45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS08285
gene id: 1050174:CEPID_RS08285
uniprot id: A0A0G3GVJ6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1050174:CEPID RS05050
gene id: 1050174:CEPID_RS05050
uniprot id: A0A0G3GTN5
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

1050174:CEPID RS02375
gene id: 1050174:CEPID_RS02375
uniprot id: A0A0G3GU33
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1050174:CEPID RS00835
gene id: 1050174:CEPID_RS00835
uniprot id: A0A0G3GLF6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

1050174:CEPID RS04995
gene id: 1050174:CEPID_RS04995
uniprot id: A0A0G3GVM0
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1050174:CEPID RS10495
gene id: 1050174:CEPID_RS10495
uniprot id: A0A0G3GTX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1050174:CEPID RS06500
gene id: 1050174:CEPID_RS06500
uniprot id: A0A0G3GPY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1050174:CEPID RS01210
gene id: 1050174:CEPID_RS01210
uniprot id: A0A0G3GLZ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS06375
gene id: 1050174:CEPID_RS06375
uniprot id: A0A0G3GPX0
names: Similarity
messages: Belongs to the UPF0237 family.

1050174:CEPID RS05745
gene id: 1050174:CEPID_RS05745
uniprot id: A0A0G3GR45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1050174:CEPID RS11555
gene id: 1050174:CEPID_RS11555
uniprot id: A0A0G3GUN1
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

1050174:CEPID RS04715
gene id: 1050174:CEPID_RS04715
uniprot id: A0A0G3GNP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1050174:CEPID RS05950
gene id: 1050174:CEPID_RS05950
uniprot id: A0A0G3GR78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1050174:CEPID RS10015
gene id: 1050174:CEPID_RS10015
uniprot id: A0A0G3GYG6
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1050174:CEPID RS06080
gene id: 1050174:CEPID_RS06080
uniprot id: A0A0G3GWC3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1050174:CEPID RS04895
gene id: 1050174:CEPID_RS04895
uniprot id: A0A0G3GNT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1050174:CEPID RS04765
gene id: 1050174:CEPID_RS04765
uniprot id: A0A0G3GNQ5
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS07565
gene id: 1050174:CEPID_RS07565
uniprot id: A0A0G3GV58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1050174:CEPID RS07095
gene id: 1050174:CEPID_RS07095
uniprot id: A0A0G3GWU6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1050174:CEPID RS02725
gene id: 1050174:CEPID_RS02725
uniprot id: A0A0G3GMT4
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1050174:CEPID RS03020
gene id: 1050174:CEPID_RS03020
uniprot id: A0A0G3GMR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1050174:CEPID RS06425
gene id: 1050174:CEPID_RS06425
uniprot id: A0A0G3GPX6
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1050174:CEPID RS03185
gene id: 1050174:CEPID_RS03185
uniprot id: A0A0G3GSL0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1050174:CEPID RS06210
gene id: 1050174:CEPID_RS06210
uniprot id: A0A0G3GRG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

1050174:CEPID RS04890
gene id: 1050174:CEPID_RS04890
uniprot id: A0A0G3GQP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1050174:CEPID RS02385
gene id: 1050174:CEPID_RS02385
uniprot id: A0A0G3GMK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1050174:CEPID RS04450
gene id: 1050174:CEPID_RS04450
uniprot id: A0A0G3GVC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS00595
gene id: 1050174:CEPID_RS00595
uniprot id: A0A0G3GLA2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1050174:CEPID RS11650
gene id: 1050174:CEPID_RS11650
uniprot id: A0A0G3GST0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1050174:CEPID RS08035
gene id: 1050174:CEPID_RS08035
uniprot id: A0A0G3GQP0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1050174:CEPID RS07915
gene id: 1050174:CEPID_RS07915
uniprot id: A0A0G3GSD6
names: Similarity
messages: Belongs to the HSP15 family.

1050174:CEPID RS01495
gene id: 1050174:CEPID_RS01495
uniprot id: A0A0G3GRN8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS03955
gene id: 1050174:CEPID_RS03955
uniprot id: A0A0G3GNI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1050174:CEPID RS07435
gene id: 1050174:CEPID_RS07435
uniprot id: A0A0G3GQA5
names: Similarity
messages: Belongs to the MQO family.

1050174:CEPID RS07610
gene id: 1050174:CEPID_RS07610
uniprot id: A0A0G3GX42
names: Similarity
messages: Belongs to the asparaginase 1 family.

1050174:CEPID RS08500
gene id: 1050174:CEPID_RS08500
uniprot id: A0A0G3GSV1
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1050174:CEPID RS10485
gene id: 1050174:CEPID_RS10485
uniprot id: A0A0G3GWS7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1050174:CEPID RS03635
gene id: 1050174:CEPID_RS03635
uniprot id: A0A0G3GN75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS04520
gene id: 1050174:CEPID_RS04520
uniprot id: A0A0G3GNK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1050174:CEPID RS09575
gene id: 1050174:CEPID_RS09575
uniprot id: A0A0G3GY98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1050174:CEPID RS10060
gene id: 1050174:CEPID_RS10060
uniprot id: A0A0G3GRT8
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

1050174:CEPID RS09970
gene id: 1050174:CEPID_RS09970
uniprot id: A0A0G3GWI8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1050174:CEPID RS06680
gene id: 1050174:CEPID_RS06680
uniprot id: A0A0G3GRQ9
names: Similarity
messages: Belongs to the peptidase M24B family.

1050174:CEPID RS09840
gene id: 1050174:CEPID_RS09840
uniprot id: A0A0G3GTJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1050174:CEPID RS04435
gene id: 1050174:CEPID_RS04435
uniprot id: A0A0G3GTD4
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS02400
gene id: 1050174:CEPID_RS02400
uniprot id: A0A0G3GU37
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1050174:CEPID RS11800
gene id: 1050174:CEPID_RS11800
uniprot id: A0A0G3GSU9
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS01225
gene id: 1050174:CEPID_RS01225
uniprot id: A0A0G3GTK5
names: Similarity
messages: Belongs to the catalase family.

1050174:CEPID RS11080
gene id: 1050174:CEPID_RS11080
uniprot id: A0A0G3GSK4
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1050174:CEPID RS03195
gene id: 1050174:CEPID_RS03195
uniprot id: A0A0G3GPN3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1050174:CEPID RS03845
gene id: 1050174:CEPID_RS03845
uniprot id: A0A0G3GV20
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1050174:CEPID RS06270
gene id: 1050174:CEPID_RS06270
uniprot id: A0A0G3GUG6
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS10330
gene id: 1050174:CEPID_RS10330
uniprot id: A0A0G3GTT4
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1050174:CEPID RS07345
gene id: 1050174:CEPID_RS07345
uniprot id: A0A0G3GQ83
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS05115
gene id: 1050174:CEPID_RS05115
uniprot id: A0A0G3GVP2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1050174:CEPID RS01945
gene id: 1050174:CEPID_RS01945
uniprot id: A0A0G3GM39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1050174:CEPID RS11215
gene id: 1050174:CEPID_RS11215
uniprot id: A0A0G3GZB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1050174:CEPID RS08080
gene id: 1050174:CEPID_RS08080
uniprot id: A0A0G3GQP8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS04465
gene id: 1050174:CEPID_RS04465
uniprot id: A0A0G3GQG5
names: Similarity
messages: Belongs to the ArsC family.

1050174:CEPID RS07960
gene id: 1050174:CEPID_RS07960
uniprot id: A0A0G3GSE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1050174:CEPID RS00790
gene id: 1050174:CEPID_RS00790
uniprot id: A0A0G3GLE6
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS00815
gene id: 1050174:CEPID_RS00815
uniprot id: A0A0G3GLF1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1050174:CEPID RS06365
gene id: 1050174:CEPID_RS06365
uniprot id: A0A0G3GWI1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS07405
gene id: 1050174:CEPID_RS07405
uniprot id: A0A0G3GS40
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1050174:CEPID RS08645
gene id: 1050174:CEPID_RS08645
uniprot id: A0A0G3GXV0
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1050174:CEPID RS08820
gene id: 1050174:CEPID_RS08820
uniprot id: A0A0G3GT12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1050174:CEPID RS06460
gene id: 1050174:CEPID_RS06460
uniprot id: A0A0G3GPT2
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS09955
gene id: 1050174:CEPID_RS09955
uniprot id: A0A0G3GTL3
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1050174:CEPID RS08125
gene id: 1050174:CEPID_RS08125
uniprot id: A0A0G3GSI2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1050174:CEPID RS04290
gene id: 1050174:CEPID_RS04290
uniprot id: A0A0G3GNH2
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS10650
gene id: 1050174:CEPID_RS10650
uniprot id: A0A0G3GSB5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1050174:CEPID RS05000
gene id: 1050174:CEPID_RS05000
uniprot id: A0A0G3GTM7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1050174:CEPID RS11805
gene id: 1050174:CEPID_RS11805
uniprot id: A0A0G3GZL7
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1050174:CEPID RS04945
gene id: 1050174:CEPID_RS04945
uniprot id: A0A0G3GVL0
names: Similarity
messages: Belongs to the UPF0045 family.

1050174:CEPID RS00520
gene id: 1050174:CEPID_RS00520
uniprot id: A0A0G3GN65
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

1050174:CEPID RS06630
gene id: 1050174:CEPID_RS06630
uniprot id: A0A0G3GRP9
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1050174:CEPID RS03620
gene id: 1050174:CEPID_RS03620
uniprot id: A0A0G3GSY4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1050174:CEPID RS04380
gene id: 1050174:CEPID_RS04380
uniprot id: A0A0G3GNQ6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1050174:CEPID RS08900
gene id: 1050174:CEPID_RS08900
uniprot id: A0A0G3GR90
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1050174:CEPID RS08735
gene id: 1050174:CEPID_RS08735
uniprot id: A0A0G3GXW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS06480
gene id: 1050174:CEPID_RS06480
uniprot id: A0A0G3GRL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1050174:CEPID RS09280
gene id: 1050174:CEPID_RS09280
uniprot id: A0A0G3GRD5
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS12170
gene id: 1050174:CEPID_RS12170
uniprot id: A0A0G3GUY2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS11510
gene id: 1050174:CEPID_RS11510
uniprot id: A0A0G3GSR6
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS02410
gene id: 1050174:CEPID_RS02410
uniprot id: A0A0G3GML4
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS06505
gene id: 1050174:CEPID_RS06505
uniprot id: A0A0G3GRM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1050174:CEPID RS06810
gene id: 1050174:CEPID_RS06810
uniprot id: A0A0G3GPY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1050174:CEPID RS06700
gene id: 1050174:CEPID_RS06700
uniprot id: A0A0G3GQ18
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1050174:CEPID RS03555
gene id: 1050174:CEPID_RS03555
uniprot id: A0A0G3GN62
names: Similarity
messages: Belongs to the AccD/PCCB family.

1050174:CEPID RS07230
gene id: 1050174:CEPID_RS07230
uniprot id: A0A0G3GQC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1050174:CEPID RS06570
gene id: 1050174:CEPID_RS06570
uniprot id: A0A0G3GUM8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1050174:CEPID RS07995
gene id: 1050174:CEPID_RS07995
uniprot id: A0A0G3GXA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1050174:CEPID RS06470
gene id: 1050174:CEPID_RS06470
uniprot id: A0A0G3GUK7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1050174:CEPID RS00700
gene id: 1050174:CEPID_RS00700
uniprot id: A0A0G3GR42
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1050174:CEPID RS12325
gene id: 1050174:CEPID_RS12325
uniprot id: A0A0G3GZU2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1050174:CEPID RS05110
gene id: 1050174:CEPID_RS05110
uniprot id: A0A0G3GNX4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1050174:CEPID RS06305
gene id: 1050174:CEPID_RS06305
uniprot id: A0A0G3GPV9
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1050174:CEPID RS04860
gene id: 1050174:CEPID_RS04860
uniprot id: A0A0G3GP02
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS11785
gene id: 1050174:CEPID_RS11785
uniprot id: A0A0G3GXK8
names: Similarity
messages: Belongs to the UPF0371 family.

1050174:CEPID RS03455
gene id: 1050174:CEPID_RS03455
uniprot id: A0A0G3GMY8
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1050174:CEPID RS04810
gene id: 1050174:CEPID_RS04810
uniprot id: A0A0G3GNZ2
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1050174:CEPID RS09585
gene id: 1050174:CEPID_RS09585
uniprot id: A0A0G3GWC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1050174:CEPID RS07215
gene id: 1050174:CEPID_RS07215
uniprot id: A0A0G3GQ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS02005
gene id: 1050174:CEPID_RS02005
uniprot id: A0A0G3GRY3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1050174:CEPID RS06565
gene id: 1050174:CEPID_RS06565
uniprot id: A0A0G3GWM0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1050174:CEPID RS12025
gene id: 1050174:CEPID_RS12025
uniprot id: A0A0G3GSZ2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS11850
gene id: 1050174:CEPID_RS11850
uniprot id: A0A0G3GZM3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1050174:CEPID RS11435
gene id: 1050174:CEPID_RS11435
uniprot id: A0A0G3GZF6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

1050174:CEPID RS01985
gene id: 1050174:CEPID_RS01985
uniprot id: A0A0G3GMC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1050174:CEPID RS07255
gene id: 1050174:CEPID_RS07255
uniprot id: A0A0G3GQD1
names: Similarity
messages: Belongs to the PspA/IM30 family.

1050174:CEPID RS10045
gene id: 1050174:CEPID_RS10045
uniprot id: A0A0G3GWJ9
names: Similarity
messages: Belongs to the PstS family.

1050174:CEPID RS08845
gene id: 1050174:CEPID_RS08845
uniprot id: A0A0G3GT17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1050174:CEPID RS11050
gene id: 1050174:CEPID_RS11050
uniprot id: A0A0G3GUC9
names: Similarity
messages: Belongs to the histone deacetylase family.

1050174:CEPID RS08640
gene id: 1050174:CEPID_RS08640
uniprot id: A0A0G3GR47
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1050174:CEPID RS06165
gene id: 1050174:CEPID_RS06165
uniprot id: A0A0G3GPN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1050174:CEPID RS08600
gene id: 1050174:CEPID_RS08600
uniprot id: A0A0G3GVU8
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS04790
gene id: 1050174:CEPID_RS04790
uniprot id: A0A0G3GQN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1050174:CEPID RS10555
gene id: 1050174:CEPID_RS10555
uniprot id: A0A0G3GTY9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1050174:CEPID RS02265
gene id: 1050174:CEPID_RS02265
uniprot id: A0A0G3GP66
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1050174:CEPID RS06910
gene id: 1050174:CEPID_RS06910
uniprot id: A0A0G3GQ07
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1050174:CEPID RS03630
gene id: 1050174:CEPID_RS03630
uniprot id: A0A0G3GQ05
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

1050174:CEPID RS07705
gene id: 1050174:CEPID_RS07705
uniprot id: A0A0G3GQG6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1050174:CEPID RS10140
gene id: 1050174:CEPID_RS10140
uniprot id: A0A0G3GS29
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1050174:CEPID RS04690
gene id: 1050174:CEPID_RS04690
uniprot id: A0A0G3GNP0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1050174:CEPID RS08620
gene id: 1050174:CEPID_RS08620
uniprot id: A0A0G3GXU6
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS05775
gene id: 1050174:CEPID_RS05775
uniprot id: A0A0G3GPB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1050174:CEPID RS07275
gene id: 1050174:CEPID_RS07275
uniprot id: A0A0G3GWX9
names: Similarity
messages: Belongs to the YciI family.

1050174:CEPID RS12100
gene id: 1050174:CEPID_RS12100
uniprot id: A0A0G3GT10
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1050174:CEPID RS02700
gene id: 1050174:CEPID_RS02700
uniprot id: A0A0G3GMS9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1050174:CEPID RS11480
gene id: 1050174:CEPID_RS11480
uniprot id: A0A0G3GUL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1050174:CEPID RS05425
gene id: 1050174:CEPID_RS05425
uniprot id: A0A0G3GQY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS07005
gene id: 1050174:CEPID_RS07005
uniprot id: A0A0G3GQ75
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1050174:CEPID RS01090
gene id: 1050174:CEPID_RS01090
uniprot id: A0A0G3GTI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1050174:CEPID RS03545
gene id: 1050174:CEPID_RS03545
uniprot id: A0A0G3GNC5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1050174:CEPID RS07300
gene id: 1050174:CEPID_RS07300
uniprot id: A0A0G3GWY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1050174:CEPID RS10620
gene id: 1050174:CEPID_RS10620
uniprot id: A0A0G3GWU4
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1050174:CEPID RS03520
gene id: 1050174:CEPID_RS03520
uniprot id: A0A0G3GNC0
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1050174:CEPID RS01065
gene id: 1050174:CEPID_RS01065
uniprot id: A0A0G3GRF2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1050174:CEPID RS03125
gene id: 1050174:CEPID_RS03125
uniprot id: A0A0G3GMT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1050174:CEPID RS07595
gene id: 1050174:CEPID_RS07595
uniprot id: A0A0G3GQL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1050174:CEPID RS01480
gene id: 1050174:CEPID_RS01480
uniprot id: A0A0G3GNS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1050174:CEPID RS03805
gene id: 1050174:CEPID_RS03805
uniprot id: A0A0G3GNG5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1050174:CEPID RS08525
gene id: 1050174:CEPID_RS08525
uniprot id: A0A0G3GSV5
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS09225
gene id: 1050174:CEPID_RS09225
uniprot id: A0A0G3GT89
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1050174:CEPID RS01875
gene id: 1050174:CEPID_RS01875
uniprot id: A0A0G3GTW0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1050174:CEPID RS03070
gene id: 1050174:CEPID_RS03070
uniprot id: A0A0G3GMS2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1050174:CEPID RS03370
gene id: 1050174:CEPID_RS03370
uniprot id: A0A0G3GSP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1050174:CEPID RS07445
gene id: 1050174:CEPID_RS07445
uniprot id: A0A0G3GV33
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1050174:CEPID RS01295
gene id: 1050174:CEPID_RS01295
uniprot id: A0A0G3GTL9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1050174:CEPID RS08075
gene id: 1050174:CEPID_RS08075
uniprot id: A0A0G3GSH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1050174:CEPID RS06145
gene id: 1050174:CEPID_RS06145
uniprot id: A0A0G3GPM6
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

1050174:CEPID RS02555
gene id: 1050174:CEPID_RS02555
uniprot id: A0A0G3GMP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS05640
gene id: 1050174:CEPID_RS05640
uniprot id: A0A0G3GVY0
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1050174:CEPID RS03110
gene id: 1050174:CEPID_RS03110
uniprot id: A0A0G3GSJ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1050174:CEPID RS02830
gene id: 1050174:CEPID_RS02830
uniprot id: A0A0G3GSE3
names: Similarity
messages: Belongs to the AccD/PCCB family.

1050174:CEPID RS01395
gene id: 1050174:CEPID_RS01395
uniprot id: A0A0G3GM27
names: Subcellular Location Annotation
messages: Cytoplasm

1050174:CEPID RS05645
gene id: 1050174:CEPID_RS05645
uniprot id: A0A0G3GTZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1050174:CEPID RS09850
gene id: 1050174:CEPID_RS09850
uniprot id: A0A0G3GYE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1050174:CEPID RS03365
gene id: 1050174:CEPID_RS03365
uniprot id: A0A0G3GUM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1050174:CEPID RS08040
gene id: 1050174:CEPID_RS08040
uniprot id: A0A0G3GXC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1050174:CEPID RS10960
gene id: 1050174:CEPID_RS10960
uniprot id: A0A0G3GX18
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1050174:CEPID RS00070
gene id: 1050174:CEPID_RS00070
uniprot id: A0A0G3GST1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1050174:CEPID RS09345
gene id: 1050174:CEPID_RS09345
uniprot id: A0A0G3GRN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1050174:CEPID RS02685
gene id: 1050174:CEPID_RS02685
uniprot id: A0A0G3GMI1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1050174:CEPID RS06440
gene id: 1050174:CEPID_RS06440
uniprot id: A0A0G3GWJ7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1050174:CEPID RS06340
gene id: 1050174:CEPID_RS06340
uniprot id: A0A0G3GPQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS08810
gene id: 1050174:CEPID_RS08810
uniprot id: A0A0G3GVZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

1050174:CEPID RS08215
gene id: 1050174:CEPID_RS08215
uniprot id: A0A0G3GVH8
names: Similarity
messages: Belongs to the asparagine synthetase family.

1050174:CEPID RS08055
gene id: 1050174:CEPID_RS08055
uniprot id: A0A0G3GQP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS10565
gene id: 1050174:CEPID_RS10565
uniprot id: A0A0G3GYS1
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS04250
gene id: 1050174:CEPID_RS04250
uniprot id: A0A0G3GT99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS06065
gene id: 1050174:CEPID_RS06065
uniprot id: A0A0G3GPR8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1050174:CEPID RS10635
gene id: 1050174:CEPID_RS10635
uniprot id: A0A0G3GS50
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1050174:CEPID RS01940
gene id: 1050174:CEPID_RS01940
uniprot id: A0A0G3GP08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1050174:CEPID RS05550
gene id: 1050174:CEPID_RS05550
uniprot id: A0A0G3GPC7
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS10585
gene id: 1050174:CEPID_RS10585
uniprot id: A0A0G3GS41
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1050174:CEPID RS01795
gene id: 1050174:CEPID_RS01795
uniprot id: A0A0G3GM82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1050174:CEPID RS06485
gene id: 1050174:CEPID_RS06485
uniprot id: A0A0G3GPT7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS09870
gene id: 1050174:CEPID_RS09870
uniprot id: A0A0G3GRQ6
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1050174:CEPID RS02085
gene id: 1050174:CEPID_RS02085
uniprot id: A0A0G3GM57
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1050174:CEPID RS11230
gene id: 1050174:CEPID_RS11230
uniprot id: A0A0G3GUG4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS08715
gene id: 1050174:CEPID_RS08715
uniprot id: A0A0G3GXW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

1050174:CEPID RS00570
gene id: 1050174:CEPID_RS00570
uniprot id: A0A0G3GL97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS06155
gene id: 1050174:CEPID_RS06155
uniprot id: A0A0G3GUD8
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

1050174:CEPID RS05370
gene id: 1050174:CEPID_RS05370
uniprot id: A0A0G3GP97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1050174:CEPID RS11545
gene id: 1050174:CEPID_RS11545
uniprot id: A0A0G3GXG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1050174:CEPID RS06740
gene id: 1050174:CEPID_RS06740
uniprot id: A0A0G3GWQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1050174:CEPID RS01680
gene id: 1050174:CEPID_RS01680
uniprot id: A0A0G3GNW3
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Could possibly oxidize fatty acids using specific components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS06775
gene id: 1050174:CEPID_RS06775
uniprot id: A0A0G3GQ30
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1050174:CEPID RS07845
gene id: 1050174:CEPID_RS07845
uniprot id: A0A0G3GQQ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1050174:CEPID RS07240
gene id: 1050174:CEPID_RS07240
uniprot id: A0A0G3GQ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1050174:CEPID RS08710
gene id: 1050174:CEPID_RS08710
uniprot id: A0A0G3GR59
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS01435
gene id: 1050174:CEPID_RS01435
uniprot id: A0A0G3GLW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1050174:CEPID RS07580
gene id: 1050174:CEPID_RS07580
uniprot id: A0A0G3GQD9
names: Similarity
messages: Belongs to the UPF0102 family.

1050174:CEPID RS02675
gene id: 1050174:CEPID_RS02675
uniprot id: A0A0G3GMS5
names: Similarity
messages: Belongs to the peptidase C40 family.

1050174:CEPID RS10715
gene id: 1050174:CEPID_RS10715
uniprot id: A0A0G3GYV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS01810
gene id: 1050174:CEPID_RS01810
uniprot id: A0A0G3GTV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1050174:CEPID RS01820
gene id: 1050174:CEPID_RS01820
uniprot id: A0A0G3GM88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1050174:CEPID RS03535
gene id: 1050174:CEPID_RS03535
uniprot id: A0A0G3GUW5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS07320
gene id: 1050174:CEPID_RS07320
uniprot id: A0A0G3GQ78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1050174:CEPID RS00870
gene id: 1050174:CEPID_RS00870
uniprot id: A0A0G3GLM6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1050174:CEPID RS07065
gene id: 1050174:CEPID_RS07065
uniprot id: A0A0G3GQ25
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1050174:CEPID RS01170
gene id: 1050174:CEPID_RS01170
uniprot id: A0A0G3GTJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1050174:CEPID RS08860
gene id: 1050174:CEPID_RS08860
uniprot id: A0A0G3GW01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cell inner membrane
messages: Membrane

1050174:CEPID RS08270
gene id: 1050174:CEPID_RS08270
uniprot id: A0A0G3GR00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1050174:CEPID RS01625
gene id: 1050174:CEPID_RS01625
uniprot id: A0A0G3GM55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1050174:CEPID RS01965
gene id: 1050174:CEPID_RS01965
uniprot id: A0A0G3GP13
names: Similarity
messages: Belongs to the HIBADH-related family.

1050174:CEPID RS06825
gene id: 1050174:CEPID_RS06825
uniprot id: A0A0G3GQ41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1050174:CEPID RS09925
gene id: 1050174:CEPID_RS09925
uniprot id: A0A0G3GRR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1050174:CEPID RS03850
gene id: 1050174:CEPID_RS03850
uniprot id: A0A0G3GT24
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1050174:CEPID RS05395
gene id: 1050174:CEPID_RS05395
uniprot id: A0A0G3GPA2
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

1050174:CEPID RS04085
gene id: 1050174:CEPID_RS04085
uniprot id: A0A0G3GNE4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS06835
gene id: 1050174:CEPID_RS06835
uniprot id: A0A0G3GPZ3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1050174:CEPID RS01780
gene id: 1050174:CEPID_RS01780
uniprot id: A0A0G3GM20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1050174:CEPID RS04915
gene id: 1050174:CEPID_RS04915
uniprot id: A0A0G3GQQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1050174:CEPID RS07155
gene id: 1050174:CEPID_RS07155
uniprot id: A0A0G3GQB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1050174:CEPID RS04070
gene id: 1050174:CEPID_RS04070
uniprot id: A0A0G3GT66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1050174:CEPID RS01745
gene id: 1050174:CEPID_RS01745
uniprot id: A0A0G3GM71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1050174:CEPID RS01070
gene id: 1050174:CEPID_RS01070
uniprot id: A0A0G3GLX3
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1050174:CEPID RS04080
gene id: 1050174:CEPID_RS04080
uniprot id: A0A0G3GQ90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1050174:CEPID RS09465
gene id: 1050174:CEPID_RS09465
uniprot id: A0A0G3GRH0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1050174:CEPID RS01590
gene id: 1050174:CEPID_RS01590
uniprot id: A0A0G3GTS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1050174:CEPID RS06295
gene id: 1050174:CEPID_RS06295
uniprot id: A0A0G3GWG6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1050174:CEPID RS04060
gene id: 1050174:CEPID_RS04060
uniprot id: A0A0G3GND9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

1050174:CEPID RS04970
gene id: 1050174:CEPID_RS04970
uniprot id: A0A0G3GVL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1050174:CEPID RS09890
gene id: 1050174:CEPID_RS09890
uniprot id: A0A0G3GTK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1050174:CEPID RS07075
gene id: 1050174:CEPID_RS07075
uniprot id: A0A0G3GUV6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1050174:CEPID RS07060
gene id: 1050174:CEPID_RS07060
uniprot id: A0A0G3GRX8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1050174:CEPID RS03915
gene id: 1050174:CEPID_RS03915
uniprot id: A0A0G3GNB4
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS10460
gene id: 1050174:CEPID_RS10460
uniprot id: A0A0G3GWS4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1050174:CEPID RS04230
gene id: 1050174:CEPID_RS04230
uniprot id: A0A0G3GNM6
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1050174:CEPID RS07250
gene id: 1050174:CEPID_RS07250
uniprot id: A0A0G3GUZ3
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS11560
gene id: 1050174:CEPID_RS11560
uniprot id: A0A0G3GSS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1050174:CEPID RS06370
gene id: 1050174:CEPID_RS06370
uniprot id: A0A0G3GUI6
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS09325
gene id: 1050174:CEPID_RS09325
uniprot id: A0A0G3GTB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1050174:CEPID RS05285
gene id: 1050174:CEPID_RS05285
uniprot id: A0A0G3GQW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1050174:CEPID RS06985
gene id: 1050174:CEPID_RS06985
uniprot id: A0A0G3GRW5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1050174:CEPID RS05475
gene id: 1050174:CEPID_RS05475
uniprot id: A0A0G3GQZ7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1050174:CEPID RS06075
gene id: 1050174:CEPID_RS06075
uniprot id: A0A0G3GPL6
names: Similarity
messages: Belongs to the CobH/CbiC family.

1050174:CEPID RS05585
gene id: 1050174:CEPID_RS05585
uniprot id: A0A0G3GP68
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1050174:CEPID RS01980
gene id: 1050174:CEPID_RS01980
uniprot id: A0A0G3GRX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

1050174:CEPID RS10260
gene id: 1050174:CEPID_RS10260
uniprot id: A0A0G3GRX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1050174:CEPID RS01615
gene id: 1050174:CEPID_RS01615
uniprot id: A0A0G3GTS5
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1050174:CEPID RS05540
gene id: 1050174:CEPID_RS05540
uniprot id: A0A0G3GVV7
names: Similarity
messages: Belongs to the universal stress protein A family.

1050174:CEPID RS11670
gene id: 1050174:CEPID_RS11670
uniprot id: A0A0G3GUQ1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS11410
gene id: 1050174:CEPID_RS11410
uniprot id: A0A0G3GZF1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1050174:CEPID RS10235
gene id: 1050174:CEPID_RS10235
uniprot id: A0A0G3GYJ9
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS10975
gene id: 1050174:CEPID_RS10975
uniprot id: A0A0G3GSE6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1050174:CEPID RS01995
gene id: 1050174:CEPID_RS01995
uniprot id: A0A0G3GM46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1050174:CEPID RS06510
gene id: 1050174:CEPID_RS06510
uniprot id: A0A0G3GPU2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1050174:CEPID RS00830
gene id: 1050174:CEPID_RS00830
uniprot id: A0A0G3GNB6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1050174:CEPID RS10900
gene id: 1050174:CEPID_RS10900
uniprot id: A0A0G3GSC9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1050174:CEPID RS06545
gene id: 1050174:CEPID_RS06545
uniprot id: A0A0G3GUM2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1050174:CEPID RS05350
gene id: 1050174:CEPID_RS05350
uniprot id: A0A0G3GQX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1050174:CEPID RS08550
gene id: 1050174:CEPID_RS08550
uniprot id: A0A0G3GVU0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1050174:CEPID RS08935
gene id: 1050174:CEPID_RS08935
uniprot id: A0A0G3GW15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1050174:CEPID RS06560
gene id: 1050174:CEPID_RS06560
uniprot id: A0A0G3GPV0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1050174:CEPID RS08895
gene id: 1050174:CEPID_RS08895
uniprot id: A0A0G3GT26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1050174:CEPID RS03960
gene id: 1050174:CEPID_RS03960
uniprot id: A0A0G3GQ65
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1050174:CEPID RS10175
gene id: 1050174:CEPID_RS10175
uniprot id: A0A0G3GRW2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1050174:CEPID RS03420
gene id: 1050174:CEPID_RS03420
uniprot id: A0A0G3GSQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1050174:CEPID RS08060
gene id: 1050174:CEPID_RS08060
uniprot id: A0A0G3GXC7
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS12155
gene id: 1050174:CEPID_RS12155
uniprot id: A0A0G3GZQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1050174:CEPID RS02045
gene id: 1050174:CEPID_RS02045
uniprot id: A0A0G3GRZ1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1050174:CEPID RS06620
gene id: 1050174:CEPID_RS06620
uniprot id: A0A0G3GUN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1050174:CEPID RS03575
gene id: 1050174:CEPID_RS03575
uniprot id: A0A0G3GPZ9
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1050174:CEPID RS10945
gene id: 1050174:CEPID_RS10945
uniprot id: A0A0G3GU62
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1050174:CEPID RS00410
gene id: 1050174:CEPID_RS00410
uniprot id: A0A0G3GN47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1050174:CEPID RS03375
gene id: 1050174:CEPID_RS03375
uniprot id: A0A0G3GN49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1050174:CEPID RS09920
gene id: 1050174:CEPID_RS09920
uniprot id: A0A0G3GTK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS06325
gene id: 1050174:CEPID_RS06325
uniprot id: A0A0G3GUH6
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS03690
gene id: 1050174:CEPID_RS03690
uniprot id: A0A0G3GN82
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1050174:CEPID RS08025
gene id: 1050174:CEPID_RS08025
uniprot id: A0A0G3GQV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1050174:CEPID RS08205
gene id: 1050174:CEPID_RS08205
uniprot id: A0A0G3GQR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1050174:CEPID RS05280
gene id: 1050174:CEPID_RS05280
uniprot id: A0A0G3GP82
names: Similarity
messages: Belongs to the isochorismate synthase family.

1050174:CEPID RS08780
gene id: 1050174:CEPID_RS08780
uniprot id: A0A0G3GXX6
names: Similarity
messages: Belongs to the peptidase M20A family.

1050174:CEPID RS10670
gene id: 1050174:CEPID_RS10670
uniprot id: A0A0G3GWV3
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS10245
gene id: 1050174:CEPID_RS10245
uniprot id: A0A0G3GS42
names: Similarity
messages: Belongs to the TPP enzyme family.

1050174:CEPID RS09415
gene id: 1050174:CEPID_RS09415
uniprot id: A0A0G3GW94
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1050174:CEPID RS07620
gene id: 1050174:CEPID_RS07620
uniprot id: A0A0G3GQL6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1050174:CEPID RS04165
gene id: 1050174:CEPID_RS04165
uniprot id: A0A0G3GNF7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1050174:CEPID RS05790
gene id: 1050174:CEPID_RS05790
uniprot id: A0A0G3GPG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1050174:CEPID RS06430
gene id: 1050174:CEPID_RS06430
uniprot id: A0A0G3GRK8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1050174:CEPID RS05020
gene id: 1050174:CEPID_RS05020
uniprot id: A0A0G3GVM4
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS06635
gene id: 1050174:CEPID_RS06635
uniprot id: A0A0G3GPW2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS04705
gene id: 1050174:CEPID_RS04705
uniprot id: A0A0G3GNX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1050174:CEPID RS06895
gene id: 1050174:CEPID_RS06895
uniprot id: A0A0G3GUT5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1050174:CEPID RS06750
gene id: 1050174:CEPID_RS06750
uniprot id: A0A0G3GQ26
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS06235
gene id: 1050174:CEPID_RS06235
uniprot id: A0A0G3GPP3
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1050174:CEPID RS12275
gene id: 1050174:CEPID_RS12275
uniprot id: A0A0G3GZT1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1050174:CEPID RS10875
gene id: 1050174:CEPID_RS10875
uniprot id: A0A0G3GSC2
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1050174:CEPID RS06265
gene id: 1050174:CEPID_RS06265
uniprot id: A0A0G3GWG2
names: Similarity
messages: Belongs to the UPF0098 family.

1050174:CEPID RS07495
gene id: 1050174:CEPID_RS07495
uniprot id: A0A0G3GV43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1050174:CEPID RS06650
gene id: 1050174:CEPID_RS06650
uniprot id: A0A0G3GQ08
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1050174:CEPID RS02305
gene id: 1050174:CEPID_RS02305
uniprot id: A0A0G3GS38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1050174:CEPID RS04865
gene id: 1050174:CEPID_RS04865
uniprot id: A0A0G3GQP3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1050174:CEPID RS04730
gene id: 1050174:CEPID_RS04730
uniprot id: A0A0G3GNX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS05415
gene id: 1050174:CEPID_RS05415
uniprot id: A0A0G3GTW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS06860
gene id: 1050174:CEPID_RS06860
uniprot id: A0A0G3GPZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1050174:CEPID RS02635
gene id: 1050174:CEPID_RS02635
uniprot id: A0A0G3GMH0
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1050174:CEPID RS01195
gene id: 1050174:CEPID_RS01195
uniprot id: A0A0G3GLS1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1050174:CEPID RS06300
gene id: 1050174:CEPID_RS06300
uniprot id: A0A0G3GUH0
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1050174:CEPID RS01185
gene id: 1050174:CEPID_RS01185
uniprot id: A0A0G3GNL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

1050174:CEPID RS03550
gene id: 1050174:CEPID_RS03550
uniprot id: A0A0G3GPZ4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1050174:CEPID RS05885
gene id: 1050174:CEPID_RS05885
uniprot id: A0A0G3GW36
names: Similarity
messages: Belongs to the UPF0225 family.

1050174:CEPID RS04350
gene id: 1050174:CEPID_RS04350
uniprot id: A0A0G3GTB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1050174:CEPID RS05980
gene id: 1050174:CEPID_RS05980
uniprot id: A0A0G3GPE4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS12595
gene id: 1050174:CEPID_RS12595
uniprot id: A0A0G3GT39
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1050174:CEPID RS12095
gene id: 1050174:CEPID_RS12095
uniprot id: A0A0G3GUW9
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS10735
gene id: 1050174:CEPID_RS10735
uniprot id: A0A0G3GS68
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1050174:CEPID RS09030
gene id: 1050174:CEPID_RS09030
uniprot id: A0A0G3GW32
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1050174:CEPID RS07305
gene id: 1050174:CEPID_RS07305
uniprot id: A0A0G3GV03
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS04600
gene id: 1050174:CEPID_RS04600
uniprot id: A0A0G3GTF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1050174:CEPID RS03930
gene id: 1050174:CEPID_RS03930
uniprot id: A0A0G3GNI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1050174:CEPID RS02975
gene id: 1050174:CEPID_RS02975
uniprot id: A0A0G3GUE7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1050174:CEPID RS01350
gene id: 1050174:CEPID_RS01350
uniprot id: A0A0G3GNQ2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1050174:CEPID RS09775
gene id: 1050174:CEPID_RS09775
uniprot id: A0A0G3GRW3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1050174:CEPID RS02575
gene id: 1050174:CEPID_RS02575
uniprot id: A0A0G3GS89
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1050174:CEPID RS10710
gene id: 1050174:CEPID_RS10710
uniprot id: A0A0G3GS62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1050174:CEPID RS00405
gene id: 1050174:CEPID_RS00405
uniprot id: A0A0G3GLE2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1050174:CEPID RS08150
gene id: 1050174:CEPID_RS08150
uniprot id: A0A0G3GSI6
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1050174:CEPID RS04910
gene id: 1050174:CEPID_RS04910
uniprot id: A0A0G3GP11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1050174:CEPID RS10990
gene id: 1050174:CEPID_RS10990
uniprot id: A0A0G3GSI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS07805
gene id: 1050174:CEPID_RS07805
uniprot id: A0A0G3GQI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1050174:CEPID RS04870
gene id: 1050174:CEPID_RS04870
uniprot id: A0A0G3GNS5
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1050174:CEPID RS10300
gene id: 1050174:CEPID_RS10300
uniprot id: A0A0G3GS49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS08995
gene id: 1050174:CEPID_RS08995
uniprot id: A0A0G3GRA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Membrane

1050174:CEPID RS00425
gene id: 1050174:CEPID_RS00425
uniprot id: A0A0G3GQY7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1050174:CEPID RS02335
gene id: 1050174:CEPID_RS02335
uniprot id: A0A0G3GMK0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1050174:CEPID RS09205
gene id: 1050174:CEPID_RS09205
uniprot id: A0A0G3GT84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1050174:CEPID RS04210
gene id: 1050174:CEPID_RS04210
uniprot id: A0A0G3GQB1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1050174:CEPID RS03815
gene id: 1050174:CEPID_RS03815
uniprot id: A0A0G3GN99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1050174:CEPID RS03080
gene id: 1050174:CEPID_RS03080
uniprot id: A0A0G3GSJ3
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1050174:CEPID RS06150
gene id: 1050174:CEPID_RS06150
uniprot id: A0A0G3GWE0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1050174:CEPID RS10420
gene id: 1050174:CEPID_RS10420
uniprot id: A0A0G3GTW1
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS06865
gene id: 1050174:CEPID_RS06865
uniprot id: A0A0G3GWS2
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1050174:CEPID RS04370
gene id: 1050174:CEPID_RS04370
uniprot id: A0A0G3GVB5
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1050174:CEPID RS07140
gene id: 1050174:CEPID_RS07140
uniprot id: A0A0G3GQ42
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1050174:CEPID RS02655
gene id: 1050174:CEPID_RS02655
uniprot id: A0A0G3GPD4
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS12585
gene id: 1050174:CEPID_RS12585
uniprot id: A0A0G3GZM9
names: Caution
names: Similarity
messages: Belongs to the peptidase S8 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS00930
gene id: 1050174:CEPID_RS00930
uniprot id: A0A0G3GTA4
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1050174:CEPID RS06830
gene id: 1050174:CEPID_RS06830
uniprot id: A0A0G3GRU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1050174:CEPID RS02075
gene id: 1050174:CEPID_RS02075
uniprot id: A0A0G3GME5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1050174:CEPID RS08665
gene id: 1050174:CEPID_RS08665
uniprot id: A0A0G3GR51
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1050174:CEPID RS05795
gene id: 1050174:CEPID_RS05795
uniprot id: A0A0G3GR54
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1050174:CEPID RS09330
gene id: 1050174:CEPID_RS09330
uniprot id: A0A0G3GRE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1050174:CEPID RS00210
gene id: 1050174:CEPID_RS00210
uniprot id: A0A0G3GSU7
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS01315
gene id: 1050174:CEPID_RS01315
uniprot id: A0A0G3GRK3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1050174:CEPID RS10180
gene id: 1050174:CEPID_RS10180
uniprot id: A0A0G3GYJ3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1050174:CEPID RS02570
gene id: 1050174:CEPID_RS02570
uniprot id: A0A0G3GU79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1050174:CEPID RS07690
gene id: 1050174:CEPID_RS07690
uniprot id: A0A0G3GV82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS08370
gene id: 1050174:CEPID_RS08370
uniprot id: A0A0G3GSM5
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS03590
gene id: 1050174:CEPID_RS03590
uniprot id: A0A0G3GSX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1050174:CEPID RS05355
gene id: 1050174:CEPID_RS05355
uniprot id: A0A0G3GP19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1050174:CEPID RS11665
gene id: 1050174:CEPID_RS11665
uniprot id: A0A0G3GSX5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1050174:CEPID RS11855
gene id: 1050174:CEPID_RS11855
uniprot id: A0A0G3GXM2
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1050174:CEPID RS02500
gene id: 1050174:CEPID_RS02500
uniprot id: A0A0G3GS76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1050174:CEPID RS10480
gene id: 1050174:CEPID_RS10480
uniprot id: A0A0G3GYP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1050174:CEPID RS12270
gene id: 1050174:CEPID_RS12270
uniprot id: A0A0G3GT45
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS10695
gene id: 1050174:CEPID_RS10695
uniprot id: A0A0G3GWV8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1050174:CEPID RS07130
gene id: 1050174:CEPID_RS07130
uniprot id: A0A0G3GQA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1050174:CEPID RS08510
gene id: 1050174:CEPID_RS08510
uniprot id: A0A0G3GXT0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Acyl carrier protein involved in meromycolate extension.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1050174:CEPID RS09265
gene id: 1050174:CEPID_RS09265
uniprot id: A0A0G3GW72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS05715
gene id: 1050174:CEPID_RS05715
uniprot id: A0A0G3GPF6
names: Similarity
messages: Belongs to the TlyA family.

1050174:CEPID RS01865
gene id: 1050174:CEPID_RS01865
uniprot id: A0A0G3GNZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1050174:CEPID RS02930
gene id: 1050174:CEPID_RS02930
uniprot id: A0A0G3GSG8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1050174:CEPID RS04220
gene id: 1050174:CEPID_RS04220
uniprot id: A0A0G3GV91
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

1050174:CEPID RS10380
gene id: 1050174:CEPID_RS10380
uniprot id: A0A0G3GTU4
names: Similarity
messages: Belongs to the Nth/MutY family.

1050174:CEPID RS06590
gene id: 1050174:CEPID_RS06590
uniprot id: A0A0G3GWM5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS05185
gene id: 1050174:CEPID_RS05185
uniprot id: A0A0G3GQU6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1050174:CEPID RS10820
gene id: 1050174:CEPID_RS10820
uniprot id: A0A0G3GSF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1050174:CEPID RS06380
gene id: 1050174:CEPID_RS06380
uniprot id: A0A0G3GRJ9
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1050174:CEPID RS08065
gene id: 1050174:CEPID_RS08065
uniprot id: A0A0G3GVE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1050174:CEPID RS00670
gene id: 1050174:CEPID_RS00670
uniprot id: A0A0G3GT42
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1050174:CEPID RS07145
gene id: 1050174:CEPID_RS07145
uniprot id: A0A0G3GWV4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1050174:CEPID RS06205
gene id: 1050174:CEPID_RS06205
uniprot id: A0A0G3GPU4
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1050174:CEPID RS03830
gene id: 1050174:CEPID_RS03830
uniprot id: A0A0G3GNG8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1050174:CEPID RS09750
gene id: 1050174:CEPID_RS09750
uniprot id: A0A0G3GRV6
names: Similarity
messages: Belongs to the peptidase S58 family.

1050174:CEPID RS11530
gene id: 1050174:CEPID_RS11530
uniprot id: A0A0G3GUM5
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1050174:CEPID RS10470
gene id: 1050174:CEPID_RS10470
uniprot id: A0A0G3GTX0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1050174:CEPID RS11255
gene id: 1050174:CEPID_RS11255
uniprot id: A0A0G3GUG8
names: Similarity
messages: Belongs to the AccD/PCCB family.

1050174:CEPID RS10345
gene id: 1050174:CEPID_RS10345
uniprot id: A0A0G3GWQ6
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1050174:CEPID RS09780
gene id: 1050174:CEPID_RS09780
uniprot id: A0A0G3GTI3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1050174:CEPID RS03040
gene id: 1050174:CEPID_RS03040
uniprot id: A0A0G3GPK5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1050174:CEPID RS01280
gene id: 1050174:CEPID_RS01280
uniprot id: A0A0G3GM13
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1050174:CEPID RS05070
gene id: 1050174:CEPID_RS05070
uniprot id: A0A0G3GTP0
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

1050174:CEPID RS07975
gene id: 1050174:CEPID_RS07975
uniprot id: A0A0G3GVD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1050174:CEPID RS02950
gene id: 1050174:CEPID_RS02950
uniprot id: A0A0G3GUE2
names: Similarity
messages: Belongs to the HupF/HypC family.

1050174:CEPID RS11895
gene id: 1050174:CEPID_RS11895
uniprot id: A0A0G3GSW7
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1050174:CEPID RS01870
gene id: 1050174:CEPID_RS01870
uniprot id: A0A0G3GM31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1050174:CEPID RS04065
gene id: 1050174:CEPID_RS04065
uniprot id: A0A0G3GV61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1050174:CEPID RS00780
gene id: 1050174:CEPID_RS00780
uniprot id: A0A0G3GLK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS10630
gene id: 1050174:CEPID_RS10630
uniprot id: A0A0G3GTZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

1050174:CEPID RS05015
gene id: 1050174:CEPID_RS05015
uniprot id: A0A0G3GNV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1050174:CEPID RS01255
gene id: 1050174:CEPID_RS01255
uniprot id: A0A0G3GM09
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS08925
gene id: 1050174:CEPID_RS08925
uniprot id: A0A0G3GR93
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

1050174:CEPID RS09835
gene id: 1050174:CEPID_RS09835
uniprot id: A0A0G3GRX3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1050174:CEPID RS10025
gene id: 1050174:CEPID_RS10025
uniprot id: A0A0G3GS09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1050174:CEPID RS03480
gene id: 1050174:CEPID_RS03480
uniprot id: A0A0G3GMZ5
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1050174:CEPID RS10535
gene id: 1050174:CEPID_RS10535
uniprot id: A0A0G3GTY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1050174:CEPID RS07600
gene id: 1050174:CEPID_RS07600
uniprot id: A0A0G3GS74
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1050174:CEPID RS00665
gene id: 1050174:CEPID_RS00665
uniprot id: A0A0G3GLB9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1050174:CEPID RS04010
gene id: 1050174:CEPID_RS04010
uniprot id: A0A0G3GQ74
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS05240
gene id: 1050174:CEPID_RS05240
uniprot id: A0A0G3GP00
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

1050174:CEPID RS10860
gene id: 1050174:CEPID_RS10860
uniprot id: A0A0G3GWZ5
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1050174:CEPID RS10240
gene id: 1050174:CEPID_RS10240
uniprot id: A0A0G3GWN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

1050174:CEPID RS08485
gene id: 1050174:CEPID_RS08485
uniprot id: A0A0G3GVT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

1050174:CEPID RS02270
gene id: 1050174:CEPID_RS02270
uniprot id: A0A0G3GM95
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1050174:CEPID RS06645
gene id: 1050174:CEPID_RS06645
uniprot id: A0A0G3GUP4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1050174:CEPID RS02545
gene id: 1050174:CEPID_RS02545
uniprot id: A0A0G3GU72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS05195
gene id: 1050174:CEPID_RS05195
uniprot id: A0A0G3GVQ2
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS06990
gene id: 1050174:CEPID_RS06990
uniprot id: A0A0G3GQ14
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1050174:CEPID RS02820
gene id: 1050174:CEPID_RS02820
uniprot id: A0A0G3GML5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1050174:CEPID RS07590
gene id: 1050174:CEPID_RS07590
uniprot id: A0A0G3GV63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1050174:CEPID RS12395
gene id: 1050174:CEPID_RS12395
uniprot id: A0A0G3GMH6
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS07650
gene id: 1050174:CEPID_RS07650
uniprot id: A0A0G3GS83
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1050174:CEPID RS05970
gene id: 1050174:CEPID_RS05970
uniprot id: A0A0G3GPJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1050174:CEPID RS08250
gene id: 1050174:CEPID_RS08250
uniprot id: A0A0G3GSK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1050174:CEPID RS07840
gene id: 1050174:CEPID_RS07840
uniprot id: A0A0G3GVB2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1050174:CEPID RS04050
gene id: 1050174:CEPID_RS04050
uniprot id: A0A0G3GNJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS09685
gene id: 1050174:CEPID_RS09685
uniprot id: A0A0G3GRM2
names: Function
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1050174:CEPID RS05410
gene id: 1050174:CEPID_RS05410
uniprot id: A0A0G3GVS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1050174:CEPID RS05615
gene id: 1050174:CEPID_RS05615
uniprot id: A0A0G3GVX5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta subunits.

1050174:CEPID RS08760
gene id: 1050174:CEPID_RS08760
uniprot id: A0A0G3GVY1
names: Subunit
messages: Homodimer.

1050174:CEPID RS11635
gene id: 1050174:CEPID_RS11635
uniprot id: A0A0G3GZI8
names: Similarity
messages: Belongs to the thioredoxin family.

1050174:CEPID RS08190
gene id: 1050174:CEPID_RS08190
uniprot id: A0A0G3GVH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

1050174:CEPID RS11505
gene id: 1050174:CEPID_RS11505
uniprot id: A0A0G3GUM1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1050174:CEPID RS11790
gene id: 1050174:CEPID_RS11790
uniprot id: A0A0G3GT01
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS05010
gene id: 1050174:CEPID_RS05010
uniprot id: A0A0G3GQR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1050174:CEPID RS02805
gene id: 1050174:CEPID_RS02805
uniprot id: A0A0G3GUA9
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

1050174:CEPID RS11770
gene id: 1050174:CEPID_RS11770
uniprot id: A0A0G3GUR7
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS11960
gene id: 1050174:CEPID_RS11960
uniprot id: A0A0G3GXN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1050174:CEPID RS02000
gene id: 1050174:CEPID_RS02000
uniprot id: A0A0G3GTY0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1050174:CEPID RS05055
gene id: 1050174:CEPID_RS05055
uniprot id: A0A0G3GP40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS06215
gene id: 1050174:CEPID_RS06215
uniprot id: A0A0G3GPN9
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1050174:CEPID RS05155
gene id: 1050174:CEPID_RS05155
uniprot id: A0A0G3GP59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS04610
gene id: 1050174:CEPID_RS04610
uniprot id: A0A0G3GQJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1050174:CEPID RS09300
gene id: 1050174:CEPID_RS09300
uniprot id: A0A0G3GTA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1050174:CEPID RS05680
gene id: 1050174:CEPID_RS05680
uniprot id: A0A0G3GU03
names: Similarity
messages: Belongs to the UPF0434 family.

1050174:CEPID RS05785
gene id: 1050174:CEPID_RS05785
uniprot id: A0A0G3GU19
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1050174:CEPID RS10365
gene id: 1050174:CEPID_RS10365
uniprot id: A0A0G3GYM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

1050174:CEPID RS03735
gene id: 1050174:CEPID_RS03735
uniprot id: A0A0G3GQ22
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1050174:CEPID RS04390
gene id: 1050174:CEPID_RS04390
uniprot id: A0A0G3GTC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

1050174:CEPID RS10610
gene id: 1050174:CEPID_RS10610
uniprot id: A0A0G3GS45
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS09405
gene id: 1050174:CEPID_RS09405
uniprot id: A0A0G3GRF8
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1050174:CEPID RS08180
gene id: 1050174:CEPID_RS08180
uniprot id: A0A0G3GQR4
names: Similarity
messages: Belongs to the peptidase C40 family.

1050174:CEPID RS12180
gene id: 1050174:CEPID_RS12180
uniprot id: A0A0G3GZR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1050174:CEPID RS02965
gene id: 1050174:CEPID_RS02965
uniprot id: A0A0G3GPJ0
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1050174:CEPID RS01205
gene id: 1050174:CEPID_RS01205
uniprot id: A0A0G3GRH8
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1050174:CEPID RS06260
gene id: 1050174:CEPID_RS06260
uniprot id: A0A0G3GPP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1050174:CEPID RS07385
gene id: 1050174:CEPID_RS07385
uniprot id: A0A0G3GS36
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1050174:CEPID RS04075
gene id: 1050174:CEPID_RS04075
uniprot id: A0A0G3GNJ9
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1050174:CEPID RS09245
gene id: 1050174:CEPID_RS09245
uniprot id: A0A0G3GRL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1050174:CEPID RS08625
gene id: 1050174:CEPID_RS08625
uniprot id: A0A0G3GVV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1050174:CEPID RS04920
gene id: 1050174:CEPID_RS04920
uniprot id: A0A0G3GNT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1050174:CEPID RS11730
gene id: 1050174:CEPID_RS11730
uniprot id: A0A0G3GZK5
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1050174:CEPID RS02355
gene id: 1050174:CEPID_RS02355
uniprot id: A0A0G3GS46
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1050174:CEPID RS06030
gene id: 1050174:CEPID_RS06030
uniprot id: A0A0G3GWB3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS09505
gene id: 1050174:CEPID_RS09505
uniprot id: A0A0G3GRR1
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

1050174:CEPID RS09720
gene id: 1050174:CEPID_RS09720
uniprot id: A0A0G3GWE4
names: Similarity
messages: Belongs to the DapA family.

1050174:CEPID RS01755
gene id: 1050174:CEPID_RS01755
uniprot id: A0A0G3GM16
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1050174:CEPID RS02040
gene id: 1050174:CEPID_RS02040
uniprot id: A0A0G3GTY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1050174:CEPID RS01850
gene id: 1050174:CEPID_RS01850
uniprot id: A0A0G3GTV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1050174:CEPID RS00010
gene id: 1050174:CEPID_RS00010
uniprot id: A0A0G3GMX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1050174:CEPID RS06675
gene id: 1050174:CEPID_RS06675
uniprot id: A0A0G3GQ12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1050174:CEPID RS05985
gene id: 1050174:CEPID_RS05985
uniprot id: A0A0G3GW58
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1050174:CEPID RS04570
gene id: 1050174:CEPID_RS04570
uniprot id: A0A0G3GVE0
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

1050174:CEPID RS01880
gene id: 1050174:CEPID_RS01880
uniprot id: A0A0G3GRW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1050174:CEPID RS04235
gene id: 1050174:CEPID_RS04235
uniprot id: A0A0G3GQB7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS01720
gene id: 1050174:CEPID_RS01720
uniprot id: A0A0G3GRT0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1050174:CEPID RS00245
gene id: 1050174:CEPID_RS00245
uniprot id: A0A0G3GLB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS09065
gene id: 1050174:CEPID_RS09065
uniprot id: A0A0G3GT58
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

1050174:CEPID RS08460
gene id: 1050174:CEPID_RS08460
uniprot id: A0A0G3GVN4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1050174:CEPID RS05930
gene id: 1050174:CEPID_RS05930
uniprot id: A0A0G3GPD6
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS02210
gene id: 1050174:CEPID_RS02210
uniprot id: A0A0G3GS22
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1050174:CEPID RS12185
gene id: 1050174:CEPID_RS12185
uniprot id: A0A0G3GXS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1050174:CEPID RS03415
gene id: 1050174:CEPID_RS03415
uniprot id: A0A0G3GUN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1050174:CEPID RS11095
gene id: 1050174:CEPID_RS11095
uniprot id: A0A0G3GSQ3
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

1050174:CEPID RS07855
gene id: 1050174:CEPID_RS07855
uniprot id: A0A0G3GQJ9
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1050174:CEPID RS00575
gene id: 1050174:CEPID_RS00575
uniprot id: A0A0G3GT23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS03470
gene id: 1050174:CEPID_RS03470
uniprot id: A0A0G3GN63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1050174:CEPID RS01775
gene id: 1050174:CEPID_RS01775
uniprot id: A0A0G3GNX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1050174:CEPID RS01580
gene id: 1050174:CEPID_RS01580
uniprot id: A0A0G3GNU5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1050174:CEPID RS09740
gene id: 1050174:CEPID_RS09740
uniprot id: A0A0G3GYB9
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1050174:CEPID RS06575
gene id: 1050174:CEPID_RS06575
uniprot id: A0A0G3GPZ6
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1050174:CEPID RS09680
gene id: 1050174:CEPID_RS09680
uniprot id: A0A0G3GTG4
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1050174:CEPID RS07895
gene id: 1050174:CEPID_RS07895
uniprot id: A0A0G3GQS0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1050174:CEPID RS01150
gene id: 1050174:CEPID_RS01150
uniprot id: A0A0G3GRG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1050174:CEPID RS07540
gene id: 1050174:CEPID_RS07540
uniprot id: A0A0G3GV52
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS06745
gene id: 1050174:CEPID_RS06745
uniprot id: A0A0G3GUR1
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS02485
gene id: 1050174:CEPID_RS02485
uniprot id: A0A0G3GPA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1050174:CEPID RS01330
gene id: 1050174:CEPID_RS01330
uniprot id: A0A0G3GLU5
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS09670
gene id: 1050174:CEPID_RS09670
uniprot id: A0A0G3GWD5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1050174:CEPID RS05935
gene id: 1050174:CEPID_RS05935
uniprot id: A0A0G3GW46
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS02340
gene id: 1050174:CEPID_RS02340
uniprot id: A0A0G3GP80
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1050174:CEPID RS09190
gene id: 1050174:CEPID_RS09190
uniprot id: A0A0G3GY44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1050174:CEPID RS04900
gene id: 1050174:CEPID_RS04900
uniprot id: A0A0G3GVK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1050174:CEPID RS01175
gene id: 1050174:CEPID_RS01175
uniprot id: A0A0G3GRH4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1050174:CEPID RS02650
gene id: 1050174:CEPID_RS02650
uniprot id: A0A0G3GMR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS09425
gene id: 1050174:CEPID_RS09425
uniprot id: A0A0G3GTC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1050174:CEPID RS10225
gene id: 1050174:CEPID_RS10225
uniprot id: A0A0G3GTR3
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS09710
gene id: 1050174:CEPID_RS09710
uniprot id: A0A0G3GRM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1050174:CEPID RS05340
gene id: 1050174:CEPID_RS05340
uniprot id: A0A0G3GTU0
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-66 and Arg-69) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1050174:CEPID RS10575
gene id: 1050174:CEPID_RS10575
uniprot id: A0A0G3GS99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS07225
gene id: 1050174:CEPID_RS07225
uniprot id: A0A0G3GUZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1050174:CEPID RS06805
gene id: 1050174:CEPID_RS06805
uniprot id: A0A0G3GRT4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1050174:CEPID RS04805
gene id: 1050174:CEPID_RS04805
uniprot id: A0A0G3GTJ0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1050174:CEPID RS03180
gene id: 1050174:CEPID_RS03180
uniprot id: A0A0G3GUI8
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1050174:CEPID RS06355
gene id: 1050174:CEPID_RS06355
uniprot id: A0A0G3GRJ4
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1050174:CEPID RS07750
gene id: 1050174:CEPID_RS07750
uniprot id: A0A0G3GSA0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1050174:CEPID RS10525
gene id: 1050174:CEPID_RS10525
uniprot id: A0A0G3GS28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1050174:CEPID RS01990
gene id: 1050174:CEPID_RS01990
uniprot id: A0A0G3GP17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1050174:CEPID RS03755
gene id: 1050174:CEPID_RS03755
uniprot id: A0A0G3GNF9
names: Similarity
messages: Belongs to the AccD/PCCB family.

1050174:CEPID RS11490
gene id: 1050174:CEPID_RS11490
uniprot id: A0A0G3GZG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1050174:CEPID RS04905
gene id: 1050174:CEPID_RS04905
uniprot id: A0A0G3GTK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1050174:CEPID RS08615
gene id: 1050174:CEPID_RS08615
uniprot id: A0A0G3GR43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1050174:CEPID RS05625
gene id: 1050174:CEPID_RS05625
uniprot id: A0A0G3GPE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1050174:CEPID RS02050
gene id: 1050174:CEPID_RS02050
uniprot id: A0A0G3GME0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1050174:CEPID RS11280
gene id: 1050174:CEPID_RS11280
uniprot id: A0A0G3GUH4
names: Similarity
messages: Belongs to the mycobacterial A85 antigen family.

1050174:CEPID RS07310
gene id: 1050174:CEPID_RS07310
uniprot id: A0A0G3GQE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1050174:CEPID RS10425
gene id: 1050174:CEPID_RS10425
uniprot id: A0A0G3GS10
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1050174:CEPID RS02945
gene id: 1050174:CEPID_RS02945
uniprot id: A0A0G3GMP5
names: Similarity
messages: Belongs to the HypD family.

1050174:CEPID RS02320
gene id: 1050174:CEPID_RS02320
uniprot id: A0A0G3GMA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1050174:CEPID RS04680
gene id: 1050174:CEPID_RS04680
uniprot id: A0A0G3GNW6
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS05380
gene id: 1050174:CEPID_RS05380
uniprot id: A0A0G3GP23
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1050174:CEPID RS04280
gene id: 1050174:CEPID_RS04280
uniprot id: A0A0G3GNN6
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS07800
gene id: 1050174:CEPID_RS07800
uniprot id: A0A0G3GSA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1050174:CEPID RS02560
gene id: 1050174:CEPID_RS02560
uniprot id: A0A0G3GPB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1050174:CEPID RS12300
gene id: 1050174:CEPID_RS12300
uniprot id: A0A0G3GZT6
names: Similarity
messages: Belongs to the ParB family.

1050174:CEPID RS04940
gene id: 1050174:CEPID_RS04940
uniprot id: A0A0G3GNU2
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1050174:CEPID RS00855
gene id: 1050174:CEPID_RS00855
uniprot id: A0A0G3GLG1
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1050174:CEPID RS02515
gene id: 1050174:CEPID_RS02515
uniprot id: A0A0G3GME6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1050174:CEPID RS02060
gene id: 1050174:CEPID_RS02060
uniprot id: A0A0G3GM54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1050174:CEPID RS12235
gene id: 1050174:CEPID_RS12235
uniprot id: A0A0G3GXT2
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1050174:CEPID RS00015
gene id: 1050174:CEPID_RS00015
uniprot id: A0A0G3GKY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1050174:CEPID RS10035
gene id: 1050174:CEPID_RS10035
uniprot id: A0A0G3GRT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1050174:CEPID RS01460
gene id: 1050174:CEPID_RS01460
uniprot id: A0A0G3GLW6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1050174:CEPID RS05635
gene id: 1050174:CEPID_RS05635
uniprot id: A0A0G3GP79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1050174:CEPID RS07815
gene id: 1050174:CEPID_RS07815
uniprot id: A0A0G3GVA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1050174:CEPID RS07720
gene id: 1050174:CEPID_RS07720
uniprot id: A0A0G3GQN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1050174:CEPID RS01760
gene id: 1050174:CEPID_RS01760
uniprot id: A0A0G3GTU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1050174:CEPID RS05600
gene id: 1050174:CEPID_RS05600
uniprot id: A0A0G3GPD5
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1050174:CEPID RS07370
gene id: 1050174:CEPID_RS07370
uniprot id: A0A0G3GWZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1050174:CEPID RS04355
gene id: 1050174:CEPID_RS04355
uniprot id: A0A0G3GNP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1050174:CEPID RS08095
gene id: 1050174:CEPID_RS08095
uniprot id: A0A0G3GQW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1050174:CEPID RS00030
gene id: 1050174:CEPID_RS00030
uniprot id: A0A0G3GL71
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1050174:CEPID RS02225
gene id: 1050174:CEPID_RS02225
uniprot id: A0A0G3GM85
names: Similarity
messages: Belongs to the peptidase C56 family.

1050174:CEPID RS00825
gene id: 1050174:CEPID_RS00825
uniprot id: A0A0G3GLL6
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS01445
gene id: 1050174:CEPID_RS01445
uniprot id: A0A0G3GRM9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1050174:CEPID RS02010
gene id: 1050174:CEPID_RS02010
uniprot id: A0A0G3GMD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1050174:CEPID RS07570
gene id: 1050174:CEPID_RS07570
uniprot id: A0A0G3GQK3
names: Similarity
messages: Belongs to the DprA/Smf family.

1050174:CEPID RS06720
gene id: 1050174:CEPID_RS06720
uniprot id: A0A0G3GUQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1050174:CEPID RS01805
gene id: 1050174:CEPID_RS01805
uniprot id: A0A0G3GM23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1050174:CEPID RS08245
gene id: 1050174:CEPID_RS08245
uniprot id: A0A0G3GQZ5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1050174:CEPID RS00435
gene id: 1050174:CEPID_RS00435
uniprot id: A0A0G3GN50
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS00050
gene id: 1050174:CEPID_RS00050
uniprot id: A0A0G3GQS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS09440
gene id: 1050174:CEPID_RS09440
uniprot id: A0A0G3GW99
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1050174:CEPID RS05725
gene id: 1050174:CEPID_RS05725
uniprot id: A0A0G3GP98
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1050174:CEPID RS07280
gene id: 1050174:CEPID_RS07280
uniprot id: A0A0G3GUZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1050174:CEPID RS03940
gene id: 1050174:CEPID_RS03940
uniprot id: A0A0G3GNB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

1050174:CEPID RS09875
gene id: 1050174:CEPID_RS09875
uniprot id: A0A0G3GYE6
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1050174:CEPID RS10340
gene id: 1050174:CEPID_RS10340
uniprot id: A0A0G3GYL5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS06655
gene id: 1050174:CEPID_RS06655
uniprot id: A0A0G3GRQ4
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1050174:CEPID RS04795
gene id: 1050174:CEPID_RS04795
uniprot id: A0A0G3GNQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1050174:CEPID RS08755
gene id: 1050174:CEPID_RS08755
uniprot id: A0A0G3GXX0
names: Similarity
messages: Belongs to the peptidase S33 family.

1050174:CEPID RS03825
gene id: 1050174:CEPID_RS03825
uniprot id: A0A0G3GT20
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1050174:CEPID RS00385
gene id: 1050174:CEPID_RS00385
uniprot id: A0A0G3GN43
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1050174:CEPID RS06585
gene id: 1050174:CEPID_RS06585
uniprot id: A0A0G3GPV4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS08015
gene id: 1050174:CEPID_RS08015
uniprot id: A0A0G3GXB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1050174:CEPID RS09080
gene id: 1050174:CEPID_RS09080
uniprot id: A0A0G3GW42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1050174:CEPID RS02905
gene id: 1050174:CEPID_RS02905
uniprot id: A0A0G3GSG4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1050174:CEPID RS09725
gene id: 1050174:CEPID_RS09725
uniprot id: A0A0G3GRV1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1050174:CEPID RS08145
gene id: 1050174:CEPID_RS08145
uniprot id: A0A0G3GQX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1050174:CEPID RS10560
gene id: 1050174:CEPID_RS10560
uniprot id: A0A0G3GS37
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS04310
gene id: 1050174:CEPID_RS04310
uniprot id: A0A0G3GQD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1050174:CEPID RS02980
gene id: 1050174:CEPID_RS02980
uniprot id: A0A0G3GSH6
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1050174:CEPID RS09340
gene id: 1050174:CEPID_RS09340
uniprot id: A0A0G3GW84
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1050174:CEPID RS00140
gene id: 1050174:CEPID_RS00140
uniprot id: A0A0G3GL90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1050174:CEPID RS10745
gene id: 1050174:CEPID_RS10745
uniprot id: A0A0G3GWX0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1050174:CEPID RS01660
gene id: 1050174:CEPID_RS01660
uniprot id: A0A0G3GM02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1050174:CEPID RS04480
gene id: 1050174:CEPID_RS04480
uniprot id: A0A0G3GTE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1050174:CEPID RS03330
gene id: 1050174:CEPID_RS03330
uniprot id: A0A0G3GPQ6
names: Similarity
messages: Belongs to the AccD/PCCB family.

1050174:CEPID RS07220
gene id: 1050174:CEPID_RS07220
uniprot id: A0A0G3GWW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS04880
gene id: 1050174:CEPID_RS04880
uniprot id: A0A0G3GTK2
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS00455
gene id: 1050174:CEPID_RS00455
uniprot id: A0A0G3GLF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1050174:CEPID RS08235
gene id: 1050174:CEPID_RS08235
uniprot id: A0A0G3GXG8
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1050174:CEPID RS06475
gene id: 1050174:CEPID_RS06475
uniprot id: A0A0G3GPY2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1050174:CEPID RS01085
gene id: 1050174:CEPID_RS01085
uniprot id: A0A0G3GLQ6
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS06725
gene id: 1050174:CEPID_RS06725
uniprot id: A0A0G3GQ21
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1050174:CEPID RS06580
gene id: 1050174:CEPID_RS06580
uniprot id: A0A0G3GRN9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1050174:CEPID RS06320
gene id: 1050174:CEPID_RS06320
uniprot id: A0A0G3GWH2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1050174:CEPID RS11245
gene id: 1050174:CEPID_RS11245
uniprot id: A0A0G3GXB6
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS02970
gene id: 1050174:CEPID_RS02970
uniprot id: A0A0G3GMQ0
names: Caution
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS09885
gene id: 1050174:CEPID_RS09885
uniprot id: A0A0G3GRY6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1050174:CEPID RS08030
gene id: 1050174:CEPID_RS08030
uniprot id: A0A0G3GSG3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1050174:CEPID RS03130
gene id: 1050174:CEPID_RS03130
uniprot id: A0A0G3GUH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1050174:CEPID RS06170
gene id: 1050174:CEPID_RS06170
uniprot id: A0A0G3GWE3
names: Similarity
messages: Belongs to the peptidase M18 family.

1050174:CEPID RS09570
gene id: 1050174:CEPID_RS09570
uniprot id: A0A0G3GRJ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1050174:CEPID RS05565
gene id: 1050174:CEPID_RS05565
uniprot id: A0A0G3GVW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1050174:CEPID RS01690
gene id: 1050174:CEPID_RS01690
uniprot id: A0A0G3GTT8
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1050174:CEPID RS03360
gene id: 1050174:CEPID_RS03360
uniprot id: A0A0G3GMX3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1050174:CEPID RS04495
gene id: 1050174:CEPID_RS04495
uniprot id: A0A0G3GNK0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

1050174:CEPID RS01640
gene id: 1050174:CEPID_RS01640
uniprot id: A0A0G3GTT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS09395
gene id: 1050174:CEPID_RS09395
uniprot id: A0A0G3GRP0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1050174:CEPID RS08680
gene id: 1050174:CEPID_RS08680
uniprot id: A0A0G3GSY3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1050174:CEPID RS09230
gene id: 1050174:CEPID_RS09230
uniprot id: A0A0G3GRC8
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1050174:CEPID RS08585
gene id: 1050174:CEPID_RS08585
uniprot id: A0A0G3GSW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1050174:CEPID RS05160
gene id: 1050174:CEPID_RS05160
uniprot id: A0A0G3GQU0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1050174:CEPID RS03790
gene id: 1050174:CEPID_RS03790
uniprot id: A0A0G3GN95
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1050174:CEPID RS11160
gene id: 1050174:CEPID_RS11160
uniprot id: A0A0G3GSL5
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1050174:CEPID RS02610
gene id: 1050174:CEPID_RS02610
uniprot id: A0A0G3GPC6
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1050174:CEPID RS02110
gene id: 1050174:CEPID_RS02110
uniprot id: A0A0G3GM61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS03055
gene id: 1050174:CEPID_RS03055
uniprot id: A0A0G3GSI9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1050174:CEPID RS04325
gene id: 1050174:CEPID_RS04325
uniprot id: A0A0G3GTB1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1050174:CEPID RS01860
gene id: 1050174:CEPID_RS01860
uniprot id: A0A0G3GM98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1050174:CEPID RS08815
gene id: 1050174:CEPID_RS08815
uniprot id: A0A0G3GRD3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1050174:CEPID RS07875
gene id: 1050174:CEPID_RS07875
uniprot id: A0A0G3GSC5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS05200
gene id: 1050174:CEPID_RS05200
uniprot id: A0A0G3GTR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1050174:CEPID RS06970
gene id: 1050174:CEPID_RS06970
uniprot id: A0A0G3GQ11
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

1050174:CEPID RS11515
gene id: 1050174:CEPID_RS11515
uniprot id: A0A0G3GZH0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1050174:CEPID RS04505
gene id: 1050174:CEPID_RS04505
uniprot id: A0A0G3GTE4
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1050174:CEPID RS11630
gene id: 1050174:CEPID_RS11630
uniprot id: A0A0G3GSS7
names: Similarity
messages: Belongs to the PspA/IM30 family.

1050174:CEPID RS05610
gene id: 1050174:CEPID_RS05610
uniprot id: A0A0G3GP73
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1050174:CEPID RS02550
gene id: 1050174:CEPID_RS02550
uniprot id: A0A0G3GS85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1050174:CEPID RS07820
gene id: 1050174:CEPID_RS07820
uniprot id: A0A0G3GQQ5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1050174:CEPID RS09430
gene id: 1050174:CEPID_RS09430
uniprot id: A0A0G3GRG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1050174:CEPID RS02835
gene id: 1050174:CEPID_RS02835
uniprot id: A0A0G3GMV5
names: Similarity
messages: Belongs to the AccD/PCCB family.

1050174:CEPID RS06615
gene id: 1050174:CEPID_RS06615
uniprot id: A0A0G3GWN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1050174:CEPID RS12315
gene id: 1050174:CEPID_RS12315
uniprot id: A0A0G3GV11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1050174:CEPID RS01245
gene id: 1050174:CEPID_RS01245
uniprot id: A0A0G3GTL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS03580
gene id: 1050174:CEPID_RS03580
uniprot id: A0A0G3GN67
names: Subcellular Location Annotation
messages: Cell membrane

1050174:CEPID RS07555
gene id: 1050174:CEPID_RS07555
uniprot id: A0A0G3GQD4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1050174:CEPID RS11240
gene id: 1050174:CEPID_RS11240
uniprot id: A0A0G3GZB9
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS00940
gene id: 1050174:CEPID_RS00940
uniprot id: A0A0G3GLN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 85 family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS08070
gene id: 1050174:CEPID_RS08070
uniprot id: A0A0G3GQW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS06695
gene id: 1050174:CEPID_RS06695
uniprot id: A0A0G3GUQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1050174:CEPID RS05945
gene id: 1050174:CEPID_RS05945
uniprot id: A0A0G3GPJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1050174:CEPID RS06160
gene id: 1050174:CEPID_RS06160
uniprot id: A0A0G3GPT6
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

1050174:CEPID RS09305
gene id: 1050174:CEPID_RS09305
uniprot id: A0A0G3GRD9
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1050174:CEPID RS10675
gene id: 1050174:CEPID_RS10675
uniprot id: A0A0G3GSC1
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS03765
gene id: 1050174:CEPID_RS03765
uniprot id: A0A0G3GN91
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1050174:CEPID RS08260
gene id: 1050174:CEPID_RS08260
uniprot id: A0A0G3GXH5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1050174:CEPID RS01095
gene id: 1050174:CEPID_RS01095
uniprot id: A0A0G3GRG0
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1050174:CEPID RS01250
gene id: 1050174:CEPID_RS01250
uniprot id: A0A0G3GRJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS09730
gene id: 1050174:CEPID_RS09730
uniprot id: A0A0G3GTH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1050174:CEPID RS10150
gene id: 1050174:CEPID_RS10150
uniprot id: A0A0G3GRV8
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS10840
gene id: 1050174:CEPID_RS10840
uniprot id: A0A0G3GWZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1050174:CEPID RS07630
gene id: 1050174:CEPID_RS07630
uniprot id: A0A0G3GQE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1050174:CEPID RS07500
gene id: 1050174:CEPID_RS07500
uniprot id: A0A0G3GQI6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS09705
gene id: 1050174:CEPID_RS09705
uniprot id: A0A0G3GTG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1050174:CEPID RS09485
gene id: 1050174:CEPID_RS09485
uniprot id: A0A0G3GTD5
names: Similarity
messages: Belongs to the peptidase M1 family.

1050174:CEPID RS10600
gene id: 1050174:CEPID_RS10600
uniprot id: A0A0G3GSA3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1050174:CEPID RS06855
gene id: 1050174:CEPID_RS06855
uniprot id: A0A0G3GRU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1050174:CEPID RS05650
gene id: 1050174:CEPID_RS05650
uniprot id: A0A0G3GPE5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS07460
gene id: 1050174:CEPID_RS07460
uniprot id: A0A0G3GQA9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1050174:CEPID RS03840
gene id: 1050174:CEPID_RS03840
uniprot id: A0A0G3GNA3
names: Similarity
messages: Belongs to the CsoR family.

1050174:CEPID RS06535
gene id: 1050174:CEPID_RS06535
uniprot id: A0A0G3GPU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1050174:CEPID RS10020
gene id: 1050174:CEPID_RS10020
uniprot id: A0A0G3GWJ3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1050174:CEPID RS09520
gene id: 1050174:CEPID_RS09520
uniprot id: A0A0G3GY92
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1050174:CEPID RS09200
gene id: 1050174:CEPID_RS09200
uniprot id: A0A0G3GRK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1050174:CEPID RS05030
gene id: 1050174:CEPID_RS05030
uniprot id: A0A0G3GP35
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1050174:CEPID RS11495
gene id: 1050174:CEPID_RS11495
uniprot id: A0A0G3GXF9
names: Similarity
messages: Belongs to the universal stress protein A family.

1050174:CEPID RS12040
gene id: 1050174:CEPID_RS12040
uniprot id: A0A0G3GT54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1050174:CEPID RS11995
gene id: 1050174:CEPID_RS11995
uniprot id: A0A0G3GUV1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1050174:CEPID RS07615
gene id: 1050174:CEPID_RS07615
uniprot id: A0A0G3GV68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1050174:CEPID RS11745
gene id: 1050174:CEPID_RS11745
uniprot id: A0A0G3GUR2
names: Similarity
messages: Belongs to the FPG family.

1050174:CEPID RS01845
gene id: 1050174:CEPID_RS01845
uniprot id: A0A0G3GNY9
names: Similarity
messages: Belongs to the asp23 family.

1050174:CEPID RS00130
gene id: 1050174:CEPID_RS00130
uniprot id: A0A0G3GST8
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS12280
gene id: 1050174:CEPID_RS12280
uniprot id: A0A0G3GXU0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1050174:CEPID RS01515
gene id: 1050174:CEPID_RS01515
uniprot id: A0A0G3GTQ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1050174:CEPID RS08120
gene id: 1050174:CEPID_RS08120
uniprot id: A0A0G3GQX1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1050174:CEPID RS06185
gene id: 1050174:CEPID_RS06185
uniprot id: A0A0G3GRG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1050174:CEPID RS12070
gene id: 1050174:CEPID_RS12070
uniprot id: A0A0G3GUW4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS10760
gene id: 1050174:CEPID_RS10760
uniprot id: A0A0G3GS75
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1050174:CEPID RS07530
gene id: 1050174:CEPID_RS07530
uniprot id: A0A0G3GQC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1050174:CEPID RS02495
gene id: 1050174:CEPID_RS02495
uniprot id: A0A0G3GU61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1050174:CEPID RS10955
gene id: 1050174:CEPID_RS10955
uniprot id: A0A0G3GZ13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1050174:CEPID RS07710
gene id: 1050174:CEPID_RS07710
uniprot id: A0A0G3GX55
names: Similarity
messages: Belongs to the acylphosphatase family.

1050174:CEPID RS00110
gene id: 1050174:CEPID_RS00110
uniprot id: A0A0G3GQT2
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS06690
gene id: 1050174:CEPID_RS06690
uniprot id: A0A0G3GWP5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS10280
gene id: 1050174:CEPID_RS10280
uniprot id: A0A0G3GTS3
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1050174:CEPID RS05655
gene id: 1050174:CEPID_RS05655
uniprot id: A0A0G3GR29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1050174:CEPID RS05630
gene id: 1050174:CEPID_RS05630
uniprot id: A0A0G3GR25
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1050174:CEPID RS01900
gene id: 1050174:CEPID_RS01900
uniprot id: A0A0G3GTW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1050174:CEPID RS06705
gene id: 1050174:CEPID_RS06705
uniprot id: A0A0G3GRR4
names: Similarity
messages: Belongs to the peptidase A24 family.

1050174:CEPID RS09965
gene id: 1050174:CEPID_RS09965
uniprot id: A0A0G3GYG1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1050174:CEPID RS06495
gene id: 1050174:CEPID_RS06495
uniprot id: A0A0G3GUL2
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1050174:CEPID RS04140
gene id: 1050174:CEPID_RS04140
uniprot id: A0A0G3GNF2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1050174:CEPID RS08700
gene id: 1050174:CEPID_RS08700
uniprot id: A0A0G3GRB7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1050174:CEPID RS11330
gene id: 1050174:CEPID_RS11330
uniprot id: A0A0G3GSP1
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1050174:CEPID RS05365
gene id: 1050174:CEPID_RS05365
uniprot id: A0A0G3GTU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1050174:CEPID RS02380
gene id: 1050174:CEPID_RS02380
uniprot id: A0A0G3GS51
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1050174:CEPID RS00190
gene id: 1050174:CEPID_RS00190
uniprot id: A0A0G3GQU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1050174:CEPID RS03810
gene id: 1050174:CEPID_RS03810
uniprot id: A0A0G3GQ37
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1050174:CEPID RS06220
gene id: 1050174:CEPID_RS06220
uniprot id: A0A0G3GUF5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1050174:CEPID RS01750
gene id: 1050174:CEPID_RS01750
uniprot id: A0A0G3GNX2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1050174:CEPID RS12265
gene id: 1050174:CEPID_RS12265
uniprot id: A0A0G3GV02
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

1050174:CEPID RS05685
gene id: 1050174:CEPID_RS05685
uniprot id: A0A0G3GPF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1050174:CEPID RS03705
gene id: 1050174:CEPID_RS03705
uniprot id: A0A0G3GNF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1050174:CEPID RS06100
gene id: 1050174:CEPID_RS06100
uniprot id: A0A0G3GWC9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1050174:CEPID RS04925
gene id: 1050174:CEPID_RS04925
uniprot id: A0A0G3GVK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1050174:CEPID RS01695
gene id: 1050174:CEPID_RS01695
uniprot id: A0A0G3GRS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1050174:CEPID RS06245
gene id: 1050174:CEPID_RS06245
uniprot id: A0A0G3GUG1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

1050174:CEPID RS10375
gene id: 1050174:CEPID_RS10375
uniprot id: A0A0G3GS60
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

1050174:CEPID RS06905
gene id: 1050174:CEPID_RS06905
uniprot id: A0A0G3GRV5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS04800
gene id: 1050174:CEPID_RS04800
uniprot id: A0A0G3GVI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1050174:CEPID RS11430
gene id: 1050174:CEPID_RS11430
uniprot id: A0A0G3GSQ5
names: Similarity
messages: Belongs to the pyruvate kinase family.

1050174:CEPID RS11090
gene id: 1050174:CEPID_RS11090
uniprot id: A0A0G3GX87
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1050174:CEPID RS06515
gene id: 1050174:CEPID_RS06515
uniprot id: A0A0G3GWL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

1050174:CEPID RS00600
gene id: 1050174:CEPID_RS00600
uniprot id: A0A0G3GT27
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS00450
gene id: 1050174:CEPID_RS00450
uniprot id: A0A0G3GQZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1050174:CEPID RS02200
gene id: 1050174:CEPID_RS02200
uniprot id: A0A0G3GM80
names: Similarity
messages: Belongs to the WXG100 family.

1050174:CEPID RS05580
gene id: 1050174:CEPID_RS05580
uniprot id: A0A0G3GR15
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1050174:CEPID RS07685
gene id: 1050174:CEPID_RS07685
uniprot id: A0A0G3GX52
names: Similarity
messages: Belongs to the P(II) protein family.

1050174:CEPID RS06225
gene id: 1050174:CEPID_RS06225
uniprot id: A0A0G3GPU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1050174:CEPID RS08635
gene id: 1050174:CEPID_RS08635
uniprot id: A0A0G3GSX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1050174:CEPID RS11700
gene id: 1050174:CEPID_RS11700
uniprot id: A0A0G3GST6
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1050174:CEPID RS02300
gene id: 1050174:CEPID_RS02300
uniprot id: A0A0G3GU21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1050174:CEPID RS08155
gene id: 1050174:CEPID_RS08155
uniprot id: A0A0G3GQR0
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

1050174:CEPID RS01890
gene id: 1050174:CEPID_RS01890
uniprot id: A0A0G3GNZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1050174:CEPID RS06660
gene id: 1050174:CEPID_RS06660
uniprot id: A0A0G3GPW7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1050174:CEPID RS02645
gene id: 1050174:CEPID_RS02645
uniprot id: A0A0G3GSA2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1050174:CEPID RS01550
gene id: 1050174:CEPID_RS01550
uniprot id: A0A0G3GM45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1050174:CEPID RS01895
gene id: 1050174:CEPID_RS01895
uniprot id: A0A0G3GM34
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1050174:CEPID RS06840
gene id: 1050174:CEPID_RS06840
uniprot id: A0A0G3GWR9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1050174:CEPID RS10465
gene id: 1050174:CEPID_RS10465
uniprot id: A0A0G3GS78
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1050174:CEPID RS10085
gene id: 1050174:CEPID_RS10085
uniprot id: A0A0G3GYH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1050174:CEPID RS08890
gene id: 1050174:CEPID_RS08890
uniprot id: A0A0G3GRE5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.
messages: Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes.

1050174:CEPID RS02800
gene id: 1050174:CEPID_RS02800
uniprot id: A0A0G3GML0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1050174:CEPID RS01885
gene id: 1050174:CEPID_RS01885
uniprot id: A0A0G3GMA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1050174:CEPID RS00125
gene id: 1050174:CEPID_RS00125
uniprot id: A0A0G3GL00
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1050174:CEPID RS06465
gene id: 1050174:CEPID_RS06465
uniprot id: A0A0G3GWK0
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS08320
gene id: 1050174:CEPID_RS08320
uniprot id: A0A0G3GSL6
names: Similarity
messages: Belongs to the glutamine synthetase family.

1050174:CEPID RS03785
gene id: 1050174:CEPID_RS03785
uniprot id: A0A0G3GQ32
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1050174:CEPID RS08230
gene id: 1050174:CEPID_RS08230
uniprot id: A0A0G3GQS3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1050174:CEPID RS05535
gene id: 1050174:CEPID_RS05535
uniprot id: A0A0G3GP56
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1050174:CEPID RS09620
gene id: 1050174:CEPID_RS09620
uniprot id: A0A0G3GWC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1050174:CEPID RS07295
gene id: 1050174:CEPID_RS07295
uniprot id: A0A0G3GQ73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1050174:CEPID RS05720
gene id: 1050174:CEPID_RS05720
uniprot id: A0A0G3GR40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS06870
gene id: 1050174:CEPID_RS06870
uniprot id: A0A0G3GUT1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1050174:CEPID RS00585
gene id: 1050174:CEPID_RS00585
uniprot id: A0A0G3GLH2
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS05995
gene id: 1050174:CEPID_RS05995
uniprot id: A0A0G3GPK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1050174:CEPID RS02360
gene id: 1050174:CEPID_RS02360
uniprot id: A0A0G3GMK4
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1050174:CEPID RS07545
gene id: 1050174:CEPID_RS07545
uniprot id: A0A0G3GQJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1050174:CEPID RS08405
gene id: 1050174:CEPID_RS08405
uniprot id: A0A0G3GXK9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1050174:CEPID RS04975
gene id: 1050174:CEPID_RS04975
uniprot id: A0A0G3GTM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

1050174:CEPID RS06000
gene id: 1050174:CEPID_RS06000
uniprot id: A0A0G3GR86
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS04935
gene id: 1050174:CEPID_RS04935
uniprot id: A0A0G3GP16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1050174:CEPID RS07355
gene id: 1050174:CEPID_RS07355
uniprot id: A0A0G3GV14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1050174:CEPID RS00725
gene id: 1050174:CEPID_RS00725
uniprot id: A0A0G3GR48
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1050174:CEPID RS02985
gene id: 1050174:CEPID_RS02985
uniprot id: A0A0G3GMY3
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1050174:CEPID RS06595
gene id: 1050174:CEPID_RS06595
uniprot id: A0A0G3GUN3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS01855
gene id: 1050174:CEPID_RS01855
uniprot id: A0A0G3GRV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1050174:CEPID RS01220
gene id: 1050174:CEPID_RS01220
uniprot id: A0A0G3GLS5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1050174:CEPID RS07070
gene id: 1050174:CEPID_RS07070
uniprot id: A0A0G3GWU3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1050174:CEPID RS07535
gene id: 1050174:CEPID_RS07535
uniprot id: A0A0G3GX32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1050174:CEPID RS08750
gene id: 1050174:CEPID_RS08750
uniprot id: A0A0G3GR66
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS00095
gene id: 1050174:CEPID_RS00095
uniprot id: A0A0G3GMZ2
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS11535
gene id: 1050174:CEPID_RS11535
uniprot id: A0A0G3GSR9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1050174:CEPID RS02580
gene id: 1050174:CEPID_RS02580
uniprot id: A0A0G3GMQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1050174:CEPID RS07990
gene id: 1050174:CEPID_RS07990
uniprot id: A0A0G3GQM9
names: Similarity
messages: Belongs to the asparaginase 1 family.

1050174:CEPID RS08690
gene id: 1050174:CEPID_RS08690
uniprot id: A0A0G3GXW0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

1050174:CEPID RS09380
gene id: 1050174:CEPID_RS09380
uniprot id: A0A0G3GRF3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1050174:CEPID RS03880
gene id: 1050174:CEPID_RS03880
uniprot id: A0A0G3GNH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1050174:CEPID RS03010
gene id: 1050174:CEPID_RS03010
uniprot id: A0A0G3GMY9
names: Similarity
messages: Belongs to the HupF/HypC family.

1050174:CEPID RS02620
gene id: 1050174:CEPID_RS02620
uniprot id: A0A0G3GS97
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1050174:CEPID RS06610
gene id: 1050174:CEPID_RS06610
uniprot id: A0A0G3GPV8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1050174:CEPID RS08275
gene id: 1050174:CEPID_RS08275
uniprot id: A0A0G3GSK6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1050174:CEPID RS09910
gene id: 1050174:CEPID_RS09910
uniprot id: A0A0G3GWH9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1050174:CEPID RS08210
gene id: 1050174:CEPID_RS08210
uniprot id: A0A0G3GXG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1050174:CEPID RS10360
gene id: 1050174:CEPID_RS10360
uniprot id: A0A0G3GRZ7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1050174:CEPID RS05780
gene id: 1050174:CEPID_RS05780
uniprot id: A0A0G3GW12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS03925
gene id: 1050174:CEPID_RS03925
uniprot id: A0A0G3GT38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1050174:CEPID RS02505
gene id: 1050174:CEPID_RS02505
uniprot id: A0A0G3GMN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

1050174:CEPID RS02990
gene id: 1050174:CEPID_RS02990
uniprot id: A0A0G3GPJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1050174:CEPID RS07755
gene id: 1050174:CEPID_RS07755
uniprot id: A0A0G3GQH6
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1050174:CEPID RS08885
gene id: 1050174:CEPID_RS08885
uniprot id: A0A0G3GW05
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

1050174:CEPID RS05620
gene id: 1050174:CEPID_RS05620
uniprot id: A0A0G3GTZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1050174:CEPID RS07480
gene id: 1050174:CEPID_RS07480
uniprot id: A0A0G3GS53
names: Subcellular Location Annotation
messages: Membrane

1050174:CEPID RS11055
gene id: 1050174:CEPID_RS11055
uniprot id: A0A0G3GSK0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1050174:CEPID RS06605
gene id: 1050174:CEPID_RS06605
uniprot id: A0A0G3GRP3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1050174:CEPID RS01155
gene id: 1050174:CEPID_RS01155
uniprot id: A0A0G3GLY8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1050174:CEPID RS09915
gene id: 1050174:CEPID_RS09915
uniprot id: A0A0G3GRZ2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1050174:CEPID RS08265
gene id: 1050174:CEPID_RS08265
uniprot id: A0A0G3GVJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1050174:CEPID RS00105
gene id: 1050174:CEPID_RS00105
uniprot id: A0A0G3GST4
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1050174:CEPID RS02080
gene id: 1050174:CEPID_RS02080
uniprot id: A0A0G3GP32
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1050174:CEPID RS04340
gene id: 1050174:CEPID_RS04340
uniprot id: A0A0G3GNH8
names: Similarity
messages: Belongs to the FBPase class 2 family.

1050174:CEPID RS08445
gene id: 1050174:CEPID_RS08445
uniprot id: A0A0G3GSN9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1050174:CEPID RS02070
gene id: 1050174:CEPID_RS02070
uniprot id: A0A0G3GRZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1050174:CEPID RS03995
gene id: 1050174:CEPID_RS03995
uniprot id: A0A0G3GV47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1050174:CEPID RS01100
gene id: 1050174:CEPID_RS01100
uniprot id: A0A0G3GLX8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1050174:CEPID RS05895
gene id: 1050174:CEPID_RS05895
uniprot id: A0A0G3GPI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1050174:CEPID RS07455
gene id: 1050174:CEPID_RS07455
uniprot id: A0A0G3GS48
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.