104268:D6200 RS09600
gene id: 104268:D6200_RS09600
uniprot id: A0A1M5E3R0
names: Similarity
messages: Belongs to the SusD family.

104268:D6200 RS11435
gene id: 104268:D6200_RS11435
uniprot id: A0A1M5DI16
names: Similarity
messages: Belongs to the nitroreductase family.

104268:D6200 RS15095
gene id: 104268:D6200_RS15095
uniprot id: A0A1M5CDW2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

104268:D6200 RS00050
gene id: 104268:D6200_RS00050
uniprot id: A0A1M5CD58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

104268:D6200 RS04130
gene id: 104268:D6200_RS04130
uniprot id: A0A1M5EX96
names: Subcellular Location Annotation
messages: Cytoplasm

104268:D6200 RS12455
gene id: 104268:D6200_RS12455
uniprot id: A0A1M5D7T6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

104268:D6200 RS06170
gene id: 104268:D6200_RS06170
uniprot id: A0A1M5HQI3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

104268:D6200 RS10265
gene id: 104268:D6200_RS10265
uniprot id: A0A1M5DWD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

104268:D6200 RS01505
gene id: 104268:D6200_RS01505
uniprot id: A0A1M5G369
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

104268:D6200 RS08655
gene id: 104268:D6200_RS08655
uniprot id: A0A1M5GSY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

104268:D6200 RS10135
gene id: 104268:D6200_RS10135
uniprot id: A0A1M5DXP8
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

104268:D6200 RS04405
gene id: 104268:D6200_RS04405
uniprot id: A0A1M5F0Z0
names: Similarity
messages: Belongs to the DEAD box helicase family.

104268:D6200 RS11010
gene id: 104268:D6200_RS11010
uniprot id: A0A1M5DMY1
names: Similarity
messages: Belongs to the GARS family.

104268:D6200 RS07385
gene id: 104268:D6200_RS07385
uniprot id: A0A1M5HDZ0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

104268:D6200 RS09445
gene id: 104268:D6200_RS09445
uniprot id: A0A1M5E5J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

104268:D6200 RS13540
gene id: 104268:D6200_RS13540
uniprot id: A0A1M5CVH8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS13685
gene id: 104268:D6200_RS13685
uniprot id: A0A1M5CU31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

104268:D6200 RS13880
gene id: 104268:D6200_RS13880
uniprot id: A0A1M5CRU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

104268:D6200 RS01325
gene id: 104268:D6200_RS01325
uniprot id: A0A1M5C1E7
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

104268:D6200 RS02480
gene id: 104268:D6200_RS02480
uniprot id: A0A1M5FTA2
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS13000
gene id: 104268:D6200_RS13000
uniprot id: A0A1M5D1Y2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

104268:D6200 RS06985
gene id: 104268:D6200_RS06985
uniprot id: A0A1M5H7D6
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

104268:D6200 RS04810
gene id: 104268:D6200_RS04810
uniprot id: A0A1M5F501
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

104268:D6200 RS01270
gene id: 104268:D6200_RS01270
uniprot id: A0A1M5C2Z5
names: Similarity
messages: Belongs to the BshC family.

104268:D6200 RS12720
gene id: 104268:D6200_RS12720
uniprot id: A0A1M5D4S0
names: Similarity
messages: Belongs to the asparaginase 1 family.

104268:D6200 RS09955
gene id: 104268:D6200_RS09955
uniprot id: A0A1M5E049
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

104268:D6200 RS05590
gene id: 104268:D6200_RS05590
uniprot id: A0A1M5FCZ4
names: Similarity
messages: Belongs to the DinB family.

104268:D6200 RS11195
gene id: 104268:D6200_RS11195
uniprot id: A0A1M5DKL0
names: Similarity
messages: Belongs to the SusD family.

104268:D6200 RS11410
gene id: 104268:D6200_RS11410
uniprot id: A0A1M5DIK2
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

104268:D6200 RS01440
gene id: 104268:D6200_RS01440
uniprot id: A0A1M5C0J4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS00475
gene id: 104268:D6200_RS00475
uniprot id: A0A1M5C9V3
names: Similarity
messages: Belongs to the PspA/IM30 family.

104268:D6200 RS14395
gene id: 104268:D6200_RS14395
uniprot id: A0A1M5CKY1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS08440
gene id: 104268:D6200_RS08440
uniprot id: A0A1M5GVL0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

104268:D6200 RS01230
gene id: 104268:D6200_RS01230
uniprot id: A0A1M5C2N7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS06060
gene id: 104268:D6200_RS06060
uniprot id: A0A1M5FI03
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

104268:D6200 RS07240
gene id: 104268:D6200_RS07240
uniprot id: A0A1M5H9Y9
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

104268:D6200 RS11405
gene id: 104268:D6200_RS11405
uniprot id: A0A1M5DIP0
names: Similarity
messages: Belongs to the group II decarboxylase family.

104268:D6200 RS06650
gene id: 104268:D6200_RS06650
uniprot id: A0A1M5HT94
names: Similarity
messages: Belongs to the SusD family.

104268:D6200 RS12100
gene id: 104268:D6200_RS12100
uniprot id: A0A1M5DBA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

104268:D6200 RS10385
gene id: 104268:D6200_RS10385
uniprot id: A0A1M5DUJ9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

104268:D6200 RS09705
gene id: 104268:D6200_RS09705
uniprot id: A0A1M5E2N6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

104268:D6200 RS11110
gene id: 104268:D6200_RS11110
uniprot id: A0A1M5DLJ4
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

104268:D6200 RS09660
gene id: 104268:D6200_RS09660
uniprot id: A0A1M5E3F7
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

104268:D6200 RS02945
gene id: 104268:D6200_RS02945
uniprot id: A0A1M5G9I9
names: Similarity
messages: Belongs to the peptidase M1 family.

104268:D6200 RS03750
gene id: 104268:D6200_RS03750
uniprot id: A0A1M5GI69
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

104268:D6200 RS00610
gene id: 104268:D6200_RS00610
uniprot id: A0A1M5C943
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

104268:D6200 RS07335
gene id: 104268:D6200_RS07335
uniprot id: A0A1M5HAW4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

104268:D6200 RS03385
gene id: 104268:D6200_RS03385
uniprot id: A0A1M5GEH8
names: Similarity
messages: Belongs to the pirin family.

104268:D6200 RS12770
gene id: 104268:D6200_RS12770
uniprot id: A0A1M5D546
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

104268:D6200 RS10235
gene id: 104268:D6200_RS10235
uniprot id: A0A1M5DW88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

104268:D6200 RS09770
gene id: 104268:D6200_RS09770
uniprot id: A0A1M5E1U4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

104268:D6200 RS08985
gene id: 104268:D6200_RS08985
uniprot id: A0A1M5EBY3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

104268:D6200 RS13485
gene id: 104268:D6200_RS13485
uniprot id: A0A1M5CW55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS01030
gene id: 104268:D6200_RS01030
uniprot id: A0A1M5C4N5
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

104268:D6200 RS12685
gene id: 104268:D6200_RS12685
uniprot id: A0A1M5D557
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS06970
gene id: 104268:D6200_RS06970
uniprot id: A0A1M5H6Y9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

104268:D6200 RS15175
gene id: 104268:D6200_RS15175
uniprot id: A0A1M5CD81
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

104268:D6200 RS03245
gene id: 104268:D6200_RS03245
uniprot id: A0A1M5GCX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

104268:D6200 RS03810
gene id: 104268:D6200_RS03810
uniprot id: A0A1M5GIX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

104268:D6200 RS09380
gene id: 104268:D6200_RS09380
uniprot id: A0A1M5E6H7
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

104268:D6200 RS05990
gene id: 104268:D6200_RS05990
uniprot id: A0A1M5FH79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

104268:D6200 RS10285
gene id: 104268:D6200_RS10285
uniprot id: A0A1M5DVX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

104268:D6200 RS04155
gene id: 104268:D6200_RS04155
uniprot id: A0A1M5EXT5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

104268:D6200 RS14075
gene id: 104268:D6200_RS14075
uniprot id: A0A1M5CPN5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

104268:D6200 RS01145
gene id: 104268:D6200_RS01145
uniprot id: A0A1M5C462
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

104268:D6200 RS01745
gene id: 104268:D6200_RS01745
uniprot id: A0A1M5G0H8
names: Similarity
messages: Belongs to the malate synthase family.

104268:D6200 RS02315
gene id: 104268:D6200_RS02315
uniprot id: A0A1M5FUV4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

104268:D6200 RS10770
gene id: 104268:D6200_RS10770
uniprot id: A0A1M5DQS3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

104268:D6200 RS01475
gene id: 104268:D6200_RS01475
uniprot id: A0A1M5BZZ3
names: Similarity
messages: Belongs to the peptidase M16 family.

104268:D6200 RS11930
gene id: 104268:D6200_RS11930
uniprot id: A0A1M5DCT1
names: Similarity
messages: Belongs to the RecJ family.

104268:D6200 RS10785
gene id: 104268:D6200_RS10785
uniprot id: A0A1M5DQ17
names: Similarity
messages: Belongs to the LacAB/RpiB family.

104268:D6200 RS10400
gene id: 104268:D6200_RS10400
uniprot id: A0A1M5DUE1
names: Similarity
messages: Belongs to the peptidase S8 family.

104268:D6200 RS14665
gene id: 104268:D6200_RS14665
uniprot id: A0A1M5CIT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS05735
gene id: 104268:D6200_RS05735
uniprot id: A0A1M5FEF3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

104268:D6200 RS02400
gene id: 104268:D6200_RS02400
uniprot id: A0A1M5FV15
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS12680
gene id: 104268:D6200_RS12680
uniprot id: A0A1M5D5L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

104268:D6200 RS10355
gene id: 104268:D6200_RS10355
uniprot id: A0A1M5DVA4
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

104268:D6200 RS05305
gene id: 104268:D6200_RS05305
uniprot id: A0A1M5FBT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

104268:D6200 RS09230
gene id: 104268:D6200_RS09230
uniprot id: A0A1M5E8K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

104268:D6200 RS12490
gene id: 104268:D6200_RS12490
uniprot id: A0A1M5D7S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

104268:D6200 RS13870
gene id: 104268:D6200_RS13870
uniprot id: A0A1M5CRX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

104268:D6200 RS07090
gene id: 104268:D6200_RS07090
uniprot id: A0A1M5H891
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

104268:D6200 RS12830
gene id: 104268:D6200_RS12830
uniprot id: A0A1M5D3Z9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

104268:D6200 RS06990
gene id: 104268:D6200_RS06990
uniprot id: A0A1M5H7H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

104268:D6200 RS00030
gene id: 104268:D6200_RS00030
uniprot id: A0A1M5CDA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

104268:D6200 RS12015
gene id: 104268:D6200_RS12015
uniprot id: A0A1M5DC02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

104268:D6200 RS08770
gene id: 104268:D6200_RS08770
uniprot id: A0A1M5GSH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

104268:D6200 RS13655
gene id: 104268:D6200_RS13655
uniprot id: A0A1M5CUA4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

104268:D6200 RS03175
gene id: 104268:D6200_RS03175
uniprot id: A0A1M5GC72
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

104268:D6200 RS04760
gene id: 104268:D6200_RS04760
uniprot id: A0A1M5F470
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS05210
gene id: 104268:D6200_RS05210
uniprot id: A0A1M5FAR6
names: Subunit
messages: Homodimer.

104268:D6200 RS10670
gene id: 104268:D6200_RS10670
uniprot id: A0A1M5DRH8
names: Subcellular Location Annotation
messages: Cytoplasm

104268:D6200 RS13790
gene id: 104268:D6200_RS13790
uniprot id: A0A1M5CSV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

104268:D6200 RS10900
gene id: 104268:D6200_RS10900
uniprot id: A0A1M5DNY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

104268:D6200 RS04605
gene id: 104268:D6200_RS04605
uniprot id: A0A1M5F2D6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

104268:D6200 RS09470
gene id: 104268:D6200_RS09470
uniprot id: A0A1M5E5B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

104268:D6200 RS09915
gene id: 104268:D6200_RS09915
uniprot id: A0A1M5E0A7
names: Similarity
messages: Belongs to the peptidase S66 family.

104268:D6200 RS00145
gene id: 104268:D6200_RS00145
uniprot id: A0A1M5CCA3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

104268:D6200 RS10095
gene id: 104268:D6200_RS10095
uniprot id: A0A1M5DYB6
names: Similarity
messages: Belongs to the ArsC family.

104268:D6200 RS07700
gene id: 104268:D6200_RS07700
uniprot id: A0A1M5HHL1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

104268:D6200 RS00770
gene id: 104268:D6200_RS00770
uniprot id: A0A1M5C6X5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

104268:D6200 RS04515
gene id: 104268:D6200_RS04515
uniprot id: A0A1M5F1N1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

104268:D6200 RS10010
gene id: 104268:D6200_RS10010
uniprot id: A0A1M5DZK5
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS00260
gene id: 104268:D6200_RS00260
uniprot id: A0A1M5CBC3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

104268:D6200 RS02600
gene id: 104268:D6200_RS02600
uniprot id: A0A1M5FT37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

104268:D6200 RS10070
gene id: 104268:D6200_RS10070
uniprot id: A0A1M5DYI3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

104268:D6200 RS11755
gene id: 104268:D6200_RS11755
uniprot id: A0A1M5DEX0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

104268:D6200 RS13795
gene id: 104268:D6200_RS13795
uniprot id: A0A1M5CTX0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS00320
gene id: 104268:D6200_RS00320
uniprot id: A0A1M5CAV2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

104268:D6200 RS10290
gene id: 104268:D6200_RS10290
uniprot id: A0A1M5DW52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

104268:D6200 RS09690
gene id: 104268:D6200_RS09690
uniprot id: A0A1M5E2R6
names: Similarity
messages: Belongs to the UPF0102 family.

104268:D6200 RS07575
gene id: 104268:D6200_RS07575
uniprot id: A0A1M5HGL3
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

104268:D6200 RS05520
gene id: 104268:D6200_RS05520
uniprot id: A0A1M5FCK6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

104268:D6200 RS15100
gene id: 104268:D6200_RS15100
uniprot id: A0A1M5CE89
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

104268:D6200 RS04180
gene id: 104268:D6200_RS04180
uniprot id: A0A1M5EXL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

104268:D6200 RS10365
gene id: 104268:D6200_RS10365
uniprot id: A0A1M5DUV1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

104268:D6200 RS12355
gene id: 104268:D6200_RS12355
uniprot id: A0A1M5D9U4
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

104268:D6200 RS02615
gene id: 104268:D6200_RS02615
uniprot id: A0A1M5FSY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS03915
gene id: 104268:D6200_RS03915
uniprot id: A0A1M5GK24
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

104268:D6200 RS12375
gene id: 104268:D6200_RS12375
uniprot id: A0A1M5D912
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

104268:D6200 RS12990
gene id: 104268:D6200_RS12990
uniprot id: A0A1M5D1R1
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

104268:D6200 RS02170
gene id: 104268:D6200_RS02170
uniprot id: A0A1M5FWL4
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

104268:D6200 RS12690
gene id: 104268:D6200_RS12690
uniprot id: A0A1M5D4T5
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

104268:D6200 RS13640
gene id: 104268:D6200_RS13640
uniprot id: A0A1M5CUS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

104268:D6200 RS07015
gene id: 104268:D6200_RS07015
uniprot id: A0A1M5H7U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

104268:D6200 RS05600
gene id: 104268:D6200_RS05600
uniprot id: A0A1M5FD32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

104268:D6200 RS08410
gene id: 104268:D6200_RS08410
uniprot id: A0A1M5GW31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

104268:D6200 RS13755
gene id: 104268:D6200_RS13755
uniprot id: A0A1M5CTF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

104268:D6200 RS11985
gene id: 104268:D6200_RS11985
uniprot id: A0A1M5DCB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

104268:D6200 RS12180
gene id: 104268:D6200_RS12180
uniprot id: A0A1M5DAH3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

104268:D6200 RS07755
gene id: 104268:D6200_RS07755
uniprot id: A0A1M5HI43
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

104268:D6200 RS08005
gene id: 104268:D6200_RS08005
uniprot id: A0A1M5H0D1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

104268:D6200 RS01500
gene id: 104268:D6200_RS01500
uniprot id: A0A1M5G385
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

104268:D6200 RS05710
gene id: 104268:D6200_RS05710
uniprot id: A0A1M5FE62
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

104268:D6200 RS01330
gene id: 104268:D6200_RS01330
uniprot id: A0A1M5C2F0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

104268:D6200 RS09785
gene id: 104268:D6200_RS09785
uniprot id: A0A1M5E1I8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

104268:D6200 RS11365
gene id: 104268:D6200_RS11365
uniprot id: A0A1M5DIU9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS02505
gene id: 104268:D6200_RS02505
uniprot id: A0A1M5FT52
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

104268:D6200 RS12080
gene id: 104268:D6200_RS12080
uniprot id: A0A1M5DBG8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS12315
gene id: 104268:D6200_RS12315
uniprot id: A0A1M5D9K1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

104268:D6200 RS12630
gene id: 104268:D6200_RS12630
uniprot id: A0A1M5D5W9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

104268:D6200 RS10815
gene id: 104268:D6200_RS10815
uniprot id: A0A1M5DQ94
names: Similarity
messages: Belongs to the UPF0145 family.

104268:D6200 RS06155
gene id: 104268:D6200_RS06155
uniprot id: A0A1M5HQM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

104268:D6200 RS06480
gene id: 104268:D6200_RS06480
uniprot id: A0A1M5HME6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

104268:D6200 RS11205
gene id: 104268:D6200_RS11205
uniprot id: A0A1M5DKW3
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

104268:D6200 RS05175
gene id: 104268:D6200_RS05175
uniprot id: A0A1M5F930
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS05000
gene id: 104268:D6200_RS05000
uniprot id: A0A1M5F784
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

104268:D6200 RS10690
gene id: 104268:D6200_RS10690
uniprot id: A0A1M5DRG6
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

104268:D6200 RS07705
gene id: 104268:D6200_RS07705
uniprot id: A0A1M5HHP2
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS09605
gene id: 104268:D6200_RS09605
uniprot id: A0A1M5E3J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS11300
gene id: 104268:D6200_RS11300
uniprot id: A0A1M5DJJ6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

104268:D6200 RS11255
gene id: 104268:D6200_RS11255
uniprot id: A0A1M5DK08
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

104268:D6200 RS07765
gene id: 104268:D6200_RS07765
uniprot id: A0A1M5HIB5
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

104268:D6200 RS03715
gene id: 104268:D6200_RS03715
uniprot id: A0A1M5GHT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

104268:D6200 RS15180
gene id: 104268:D6200_RS15180
uniprot id: A0A1M5CD98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

104268:D6200 RS02240
gene id: 104268:D6200_RS02240
uniprot id: A0A1M5FVP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

104268:D6200 RS03775
gene id: 104268:D6200_RS03775
uniprot id: A0A1M5GII9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

104268:D6200 RS05250
gene id: 104268:D6200_RS05250
uniprot id: A0A1M5F9W2
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

104268:D6200 RS04010
gene id: 104268:D6200_RS04010
uniprot id: A0A1M5GLC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

104268:D6200 RS11540
gene id: 104268:D6200_RS11540
uniprot id: A0A1M5DGZ5
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

104268:D6200 RS13775
gene id: 104268:D6200_RS13775
uniprot id: A0A1M5CT89
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

104268:D6200 RS09525
gene id: 104268:D6200_RS09525
uniprot id: A0A1M5E569
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS01640
gene id: 104268:D6200_RS01640
uniprot id: A0A1M5G1D4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

104268:D6200 RS09805
gene id: 104268:D6200_RS09805
uniprot id: A0A1M5E1P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

104268:D6200 RS05730
gene id: 104268:D6200_RS05730
uniprot id: A0A1M5FEM3
names: Caution
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

104268:D6200 RS10550
gene id: 104268:D6200_RS10550
uniprot id: A0A1M5DSJ4
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

104268:D6200 RS03115
gene id: 104268:D6200_RS03115
uniprot id: A0A1M5GBL2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

104268:D6200 RS03950
gene id: 104268:D6200_RS03950
uniprot id: A0A1M5GKL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

104268:D6200 RS02750
gene id: 104268:D6200_RS02750
uniprot id: A0A1M5FQP4
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS03730
gene id: 104268:D6200_RS03730
uniprot id: A0A1M5GI53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS08070
gene id: 104268:D6200_RS08070
uniprot id: A0A1M5GZK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

104268:D6200 RS03495
gene id: 104268:D6200_RS03495
uniprot id: A0A1M5GG84
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

104268:D6200 RS12090
gene id: 104268:D6200_RS12090
uniprot id: A0A1M5DBD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

104268:D6200 RS00870
gene id: 104268:D6200_RS00870
uniprot id: A0A1M5C5T4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

104268:D6200 RS10795
gene id: 104268:D6200_RS10795
uniprot id: A0A1M5DQ61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

104268:D6200 RS03980
gene id: 104268:D6200_RS03980
uniprot id: A0A1M5GLG7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

104268:D6200 RS01355
gene id: 104268:D6200_RS01355
uniprot id: A0A1M5C184
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

104268:D6200 RS00460
gene id: 104268:D6200_RS00460
uniprot id: A0A1M5C9V1
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

104268:D6200 RS11760
gene id: 104268:D6200_RS11760
uniprot id: A0A1M5DER8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

104268:D6200 RS06220
gene id: 104268:D6200_RS06220
uniprot id: A0A1M5HPZ4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

104268:D6200 RS15215
gene id: 104268:D6200_RS15215
uniprot id: A0A1M5CCW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

104268:D6200 RS02115
gene id: 104268:D6200_RS02115
uniprot id: A0A1M5FWM5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

104268:D6200 RS04175
gene id: 104268:D6200_RS04175
uniprot id: A0A1M5EXQ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

104268:D6200 RS03575
gene id: 104268:D6200_RS03575
uniprot id: A0A1M5GG69
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

104268:D6200 RS11400
gene id: 104268:D6200_RS11400
uniprot id: A0A1M5DI90
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

104268:D6200 RS10860
gene id: 104268:D6200_RS10860
uniprot id: A0A1M5DPE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

104268:D6200 RS02100
gene id: 104268:D6200_RS02100
uniprot id: A0A1M5FWS3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

104268:D6200 RS03705
gene id: 104268:D6200_RS03705
uniprot id: A0A1M5GHK3
names: Similarity
messages: Belongs to the DEAD box helicase family.

104268:D6200 RS03835
gene id: 104268:D6200_RS03835
uniprot id: A0A1M5GJB5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS14705
gene id: 104268:D6200_RS14705
uniprot id: A0A1M5CHD6
names: Function
messages: May be involved in the biogenesis of curli organelles.

104268:D6200 RS00430
gene id: 104268:D6200_RS00430
uniprot id: A0A1M5CA43
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

104268:D6200 RS06750
gene id: 104268:D6200_RS06750
uniprot id: A0A1M5H4P9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

104268:D6200 RS10300
gene id: 104268:D6200_RS10300
uniprot id: A0A1M5DVD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

104268:D6200 RS02395
gene id: 104268:D6200_RS02395
uniprot id: A0A1M5FV24
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

104268:D6200 RS03830
gene id: 104268:D6200_RS03830
uniprot id: A0A1M5GJ66
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

104268:D6200 RS03410
gene id: 104268:D6200_RS03410
uniprot id: A0A1M5GFB6
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

104268:D6200 RS14450
gene id: 104268:D6200_RS14450
uniprot id: A0A1M5CKC6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

104268:D6200 RS05195
gene id: 104268:D6200_RS05195
uniprot id: A0A1M5F9F5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

104268:D6200 RS07810
gene id: 104268:D6200_RS07810
uniprot id: A0A1M5HIS7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

104268:D6200 RS05205
gene id: 104268:D6200_RS05205
uniprot id: A0A1M5FAP6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

104268:D6200 RS14120
gene id: 104268:D6200_RS14120
uniprot id: A0A1M5CP84
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS11390
gene id: 104268:D6200_RS11390
uniprot id: A0A1M5DIT5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

104268:D6200 RS06775
gene id: 104268:D6200_RS06775
uniprot id: A0A1M5H508
names: Similarity
messages: Belongs to the OsmC/Ohr family.

104268:D6200 RS04495
gene id: 104268:D6200_RS04495
uniprot id: A0A1M5F198
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

104268:D6200 RS06615
gene id: 104268:D6200_RS06615
uniprot id: A0A1M5HSW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

104268:D6200 RS00240
gene id: 104268:D6200_RS00240
uniprot id: A0A1M5CBI8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

104268:D6200 RS13015
gene id: 104268:D6200_RS13015
uniprot id: A0A1M5D1H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

104268:D6200 RS06935
gene id: 104268:D6200_RS06935
uniprot id: A0A1M5H6U0
names: Similarity
messages: Belongs to the universal stress protein A family.

104268:D6200 RS03965
gene id: 104268:D6200_RS03965
uniprot id: A0A1M5GKM5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS05120
gene id: 104268:D6200_RS05120
uniprot id: A0A1M5F8M3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

104268:D6200 RS12810
gene id: 104268:D6200_RS12810
uniprot id: A0A1M5D4K8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

104268:D6200 RS02435
gene id: 104268:D6200_RS02435
uniprot id: A0A1M5FTT2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

104268:D6200 RS08420
gene id: 104268:D6200_RS08420
uniprot id: A0A1M5GVV9
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS12510
gene id: 104268:D6200_RS12510
uniprot id: A0A1M5D7D7
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

104268:D6200 RS08940
gene id: 104268:D6200_RS08940
uniprot id: A0A1M5EBZ1
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS05440
gene id: 104268:D6200_RS05440
uniprot id: A0A1M5FBQ3
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS00095
gene id: 104268:D6200_RS00095
uniprot id: A0A1M5CCU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

104268:D6200 RS09120
gene id: 104268:D6200_RS09120
uniprot id: A0A1M5E9N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

104268:D6200 RS14630
gene id: 104268:D6200_RS14630
uniprot id: A0A1M5CIB3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

104268:D6200 RS10625
gene id: 104268:D6200_RS10625
uniprot id: A0A1M5DRS5
names: Similarity
messages: Belongs to the peptidase S9A family.

104268:D6200 RS05545
gene id: 104268:D6200_RS05545
uniprot id: A0A1M5FCL3
names: Similarity
messages: Belongs to the ArsC family.

104268:D6200 RS05690
gene id: 104268:D6200_RS05690
uniprot id: A0A1M5FE74
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

104268:D6200 RS12955
gene id: 104268:D6200_RS12955
uniprot id: A0A1M5D2F5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

104268:D6200 RS01815
gene id: 104268:D6200_RS01815
uniprot id: A0A1M5FZT3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

104268:D6200 RS11250
gene id: 104268:D6200_RS11250
uniprot id: A0A1M5DJR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

104268:D6200 RS14310
gene id: 104268:D6200_RS14310
uniprot id: A0A1M5CLV6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

104268:D6200 RS03275
gene id: 104268:D6200_RS03275
uniprot id: A0A1M5GD92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

104268:D6200 RS12975
gene id: 104268:D6200_RS12975
uniprot id: A0A1M5D213
names: Similarity
messages: Belongs to the glutathione peroxidase family.

104268:D6200 RS04865
gene id: 104268:D6200_RS04865
uniprot id: A0A1M5F5M0
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS09765
gene id: 104268:D6200_RS09765
uniprot id: A0A1M5E1Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

104268:D6200 RS04990
gene id: 104268:D6200_RS04990
uniprot id: A0A1M5F725
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

104268:D6200 RS04730
gene id: 104268:D6200_RS04730
uniprot id: A0A1M5F4W1
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS01395
gene id: 104268:D6200_RS01395
uniprot id: A0A1M5C0U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

104268:D6200 RS03485
gene id: 104268:D6200_RS03485
uniprot id: A0A1M5GFJ8
names: Similarity
messages: Belongs to the HSP15 family.

104268:D6200 RS05375
gene id: 104268:D6200_RS05375
uniprot id: A0A1M5FBA6
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS14060
gene id: 104268:D6200_RS14060
uniprot id: A0A1M5CQU0
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS15130
gene id: 104268:D6200_RS15130
uniprot id: A0A1M5CDL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS02410
gene id: 104268:D6200_RS02410
uniprot id: A0A1M5FU85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

104268:D6200 RS06140
gene id: 104268:D6200_RS06140
uniprot id: A0A1M5HQT8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

104268:D6200 RS04425
gene id: 104268:D6200_RS04425
uniprot id: A0A1M5F166
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

104268:D6200 RS13370
gene id: 104268:D6200_RS13370
uniprot id: A0A1M5CXN6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

104268:D6200 RS04925
gene id: 104268:D6200_RS04925
uniprot id: A0A1M5F6F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

104268:D6200 RS05140
gene id: 104268:D6200_RS05140
uniprot id: A0A1M5F8F4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

104268:D6200 RS01830
gene id: 104268:D6200_RS01830
uniprot id: A0A1M5FZH0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

104268:D6200 RS04995
gene id: 104268:D6200_RS04995
uniprot id: A0A1M5F775
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS00420
gene id: 104268:D6200_RS00420
uniprot id: A0A1M5C9Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

104268:D6200 RS14610
gene id: 104268:D6200_RS14610
uniprot id: A0A1M5CIB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

104268:D6200 RS02250
gene id: 104268:D6200_RS02250
uniprot id: A0A1M5FVB6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

104268:D6200 RS04825
gene id: 104268:D6200_RS04825
uniprot id: A0A1M5F573
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

104268:D6200 RS06745
gene id: 104268:D6200_RS06745
uniprot id: A0A1M5H492
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

104268:D6200 RS04035
gene id: 104268:D6200_RS04035
uniprot id: A0A1M5GLG4
names: Similarity
messages: Belongs to the group II decarboxylase family.

104268:D6200 RS00270
gene id: 104268:D6200_RS00270
uniprot id: A0A1M5CBC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

104268:D6200 RS03285
gene id: 104268:D6200_RS03285
uniprot id: A0A1M5GDI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

104268:D6200 RS04920
gene id: 104268:D6200_RS04920
uniprot id: A0A1M5F6E4
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS10230
gene id: 104268:D6200_RS10230
uniprot id: A0A1M5DWK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

104268:D6200 RS11800
gene id: 104268:D6200_RS11800
uniprot id: A0A1M5DE98
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

104268:D6200 RS11980
gene id: 104268:D6200_RS11980
uniprot id: A0A1M5DCC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

104268:D6200 RS04550
gene id: 104268:D6200_RS04550
uniprot id: A0A1M5F249
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS05365
gene id: 104268:D6200_RS05365
uniprot id: A0A1M5FC82
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

104268:D6200 RS10635
gene id: 104268:D6200_RS10635
uniprot id: A0A1M5DRT7
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

104268:D6200 RS01275
gene id: 104268:D6200_RS01275
uniprot id: A0A1M5C1V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

104268:D6200 RS14520
gene id: 104268:D6200_RS14520
uniprot id: A0A1M5CJC4
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

104268:D6200 RS02985
gene id: 104268:D6200_RS02985
uniprot id: A0A1M5GAT2
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

104268:D6200 RS02710
gene id: 104268:D6200_RS02710
uniprot id: A0A1M5FR00
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-54 and Arg-57) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

104268:D6200 RS04220
gene id: 104268:D6200_RS04220
uniprot id: A0A1M5EYD7
names: Similarity
messages: Belongs to the peptidase S51 family.

104268:D6200 RS05935
gene id: 104268:D6200_RS05935
uniprot id: A0A1M5FGI4
names: Similarity
messages: Belongs to the nitroreductase family.

104268:D6200 RS09925
gene id: 104268:D6200_RS09925
uniprot id: A0A1M5E048
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

104268:D6200 RS02845
gene id: 104268:D6200_RS02845
uniprot id: A0A1M5HUN2
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS02255
gene id: 104268:D6200_RS02255
uniprot id: A0A1M5FWB1
names: Similarity
messages: Belongs to the CarB family.

104268:D6200 RS01695
gene id: 104268:D6200_RS01695
uniprot id: A0A1M5G172
names: Similarity
messages: Belongs to the UPF0173 family.

104268:D6200 RS09410
gene id: 104268:D6200_RS09410
uniprot id: A0A1M5E5Z2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

104268:D6200 RS14750
gene id: 104268:D6200_RS14750
uniprot id: A0A1M5CHE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

104268:D6200 RS15205
gene id: 104268:D6200_RS15205
uniprot id: A0A1M5CCZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

104268:D6200 RS11975
gene id: 104268:D6200_RS11975
uniprot id: A0A1M5DD53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

104268:D6200 RS14990
gene id: 104268:D6200_RS14990
uniprot id: A0A1M5CEU5
names: Similarity
messages: Belongs to the peptidase S8 family.

104268:D6200 RS12950
gene id: 104268:D6200_RS12950
uniprot id: A0A1M5D2P2
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

104268:D6200 RS10565
gene id: 104268:D6200_RS10565
uniprot id: A0A1M5DSC7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

104268:D6200 RS12870
gene id: 104268:D6200_RS12870
uniprot id: A0A1M5D3F2
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

104268:D6200 RS00310
gene id: 104268:D6200_RS00310
uniprot id: A0A1M5CAW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

104268:D6200 RS09320
gene id: 104268:D6200_RS09320
uniprot id: A0A1M5E7K0
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

104268:D6200 RS08000
gene id: 104268:D6200_RS08000
uniprot id: A0A1M5H0B7
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

104268:D6200 RS12735
gene id: 104268:D6200_RS12735
uniprot id: A0A1M5D5H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

104268:D6200 RS15150
gene id: 104268:D6200_RS15150
uniprot id: A0A1M5CDJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

104268:D6200 RS07030
gene id: 104268:D6200_RS07030
uniprot id: A0A1M5H7V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

104268:D6200 RS12925
gene id: 104268:D6200_RS12925
uniprot id: A0A1M5D2X1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

104268:D6200 RS13420
gene id: 104268:D6200_RS13420
uniprot id: A0A1M5CWW6
names: Similarity
messages: Belongs to the proline racemase family.

104268:D6200 RS12145
gene id: 104268:D6200_RS12145
uniprot id: A0A1M5DBI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

104268:D6200 RS11600
gene id: 104268:D6200_RS11600
uniprot id: A0A1M5DGI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

104268:D6200 RS00580
gene id: 104268:D6200_RS00580
uniprot id: A0A1M5C8V4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

104268:D6200 RS14205
gene id: 104268:D6200_RS14205
uniprot id: A0A1M5CN74
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

104268:D6200 RS14330
gene id: 104268:D6200_RS14330
uniprot id: A0A1M5CMI7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

104268:D6200 RS02490
gene id: 104268:D6200_RS02490
uniprot id: A0A1M5FU82
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

104268:D6200 RS08760
gene id: 104268:D6200_RS08760
uniprot id: A0A1M5GSD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

104268:D6200 RS09730
gene id: 104268:D6200_RS09730
uniprot id: A0A1M5E2F1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS03365
gene id: 104268:D6200_RS03365
uniprot id: A0A1M5GE75
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

104268:D6200 RS00110
gene id: 104268:D6200_RS00110
uniprot id: A0A1M5CCS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

104268:D6200 RS06230
gene id: 104268:D6200_RS06230
uniprot id: A0A1M5HPV3
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS11915
gene id: 104268:D6200_RS11915
uniprot id: A0A1M5DDT9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS04305
gene id: 104268:D6200_RS04305
uniprot id: A0A1M5EZ73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

104268:D6200 RS00650
gene id: 104268:D6200_RS00650
uniprot id: A0A1M5C869
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

104268:D6200 RS01300
gene id: 104268:D6200_RS01300
uniprot id: A0A1M5C1S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

104268:D6200 RS03955
gene id: 104268:D6200_RS03955
uniprot id: A0A1M5GKM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

104268:D6200 RS10595
gene id: 104268:D6200_RS10595
uniprot id: A0A1M5DS78
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

104268:D6200 RS14365
gene id: 104268:D6200_RS14365
uniprot id: A0A1M5CLD5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

104268:D6200 RS09100
gene id: 104268:D6200_RS09100
uniprot id: A0A1M5EAI5
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

104268:D6200 RS00635
gene id: 104268:D6200_RS00635
uniprot id: A0A1M5C7Z6
names: Similarity
messages: Belongs to the UPF0047 family.

104268:D6200 RS08015
gene id: 104268:D6200_RS08015
uniprot id: A0A1M5H024
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

104268:D6200 RS08965
gene id: 104268:D6200_RS08965
uniprot id: A0A1M5EBU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

104268:D6200 RS08205
gene id: 104268:D6200_RS08205
uniprot id: A0A1M5GYC7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

104268:D6200 RS04430
gene id: 104268:D6200_RS04430
uniprot id: A0A1M5F0F6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

104268:D6200 RS14505
gene id: 104268:D6200_RS14505
uniprot id: A0A1M5CKH0
names: Similarity
messages: Belongs to the SusD family.

104268:D6200 RS08640
gene id: 104268:D6200_RS08640
uniprot id: A0A1M5GTE4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS10270
gene id: 104268:D6200_RS10270
uniprot id: A0A1M5DVX4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS12170
gene id: 104268:D6200_RS12170
uniprot id: A0A1M5DBC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS15210
gene id: 104268:D6200_RS15210
uniprot id: A0A1M5CCZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

104268:D6200 RS02835
gene id: 104268:D6200_RS02835
uniprot id: A0A1M5HUH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

104268:D6200 RS03250
gene id: 104268:D6200_RS03250
uniprot id: A0A1M5GCZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

104268:D6200 RS14780
gene id: 104268:D6200_RS14780
uniprot id: A0A1M5CGQ5
names: Similarity
messages: Belongs to the nitroreductase family.

104268:D6200 RS12095
gene id: 104268:D6200_RS12095
uniprot id: A0A1M5DBI1
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

104268:D6200 RS10765
gene id: 104268:D6200_RS10765
uniprot id: A0A1M5DQG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

104268:D6200 RS00335
gene id: 104268:D6200_RS00335
uniprot id: A0A1M5CAP1
names: Similarity
messages: Belongs to the peptidase C40 family.

104268:D6200 RS09670
gene id: 104268:D6200_RS09670
uniprot id: A0A1M5E312
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS09940
gene id: 104268:D6200_RS09940
uniprot id: A0A1M5DZS6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

104268:D6200 RS13875
gene id: 104268:D6200_RS13875
uniprot id: A0A1M5CSZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

104268:D6200 RS11270
gene id: 104268:D6200_RS11270
uniprot id: A0A1M5DJM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

104268:D6200 RS09545
gene id: 104268:D6200_RS09545
uniprot id: A0A1M5E4X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

104268:D6200 RS12845
gene id: 104268:D6200_RS12845
uniprot id: A0A1M5D3B0
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

104268:D6200 RS13635
gene id: 104268:D6200_RS13635
uniprot id: A0A1M5CUI6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

104268:D6200 RS13805
gene id: 104268:D6200_RS13805
uniprot id: A0A1M5CSM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

104268:D6200 RS10390
gene id: 104268:D6200_RS10390
uniprot id: A0A1M5DUI1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

104268:D6200 RS12890
gene id: 104268:D6200_RS12890
uniprot id: A0A1M5D3A2
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS07095
gene id: 104268:D6200_RS07095
uniprot id: A0A1M5H8H1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

104268:D6200 RS12160
gene id: 104268:D6200_RS12160
uniprot id: A0A1M5DAT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS02920
gene id: 104268:D6200_RS02920
uniprot id: A0A1M5GA26
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

104268:D6200 RS06225
gene id: 104268:D6200_RS06225
uniprot id: A0A1M5HPZ2
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS15535
gene id: 104268:D6200_RS15535
uniprot id: A0A1M5DBM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS10740
gene id: 104268:D6200_RS10740
uniprot id: A0A1M5DQK6
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

104268:D6200 RS00025
gene id: 104268:D6200_RS00025
uniprot id: A0A1M5CDH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

104268:D6200 RS07055
gene id: 104268:D6200_RS07055
uniprot id: A0A1M5H7V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

104268:D6200 RS03570
gene id: 104268:D6200_RS03570
uniprot id: A0A1M5GGC0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

104268:D6200 RS13135
gene id: 104268:D6200_RS13135
uniprot id: A0A1M5D0E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

104268:D6200 RS12500
gene id: 104268:D6200_RS12500
uniprot id: A0A1M5D7R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

104268:D6200 RS07770
gene id: 104268:D6200_RS07770
uniprot id: A0A1M5HIA2
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS04490
gene id: 104268:D6200_RS04490
uniprot id: A0A1M5F0Y5
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

104268:D6200 RS00150
gene id: 104268:D6200_RS00150
uniprot id: A0A1M5CCA0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

104268:D6200 RS04485
gene id: 104268:D6200_RS04485
uniprot id: A0A1M5F1R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

104268:D6200 RS14720
gene id: 104268:D6200_RS14720
uniprot id: A0A1M5CH86
names: Similarity
messages: Belongs to the AIR synthase family.

104268:D6200 RS11885
gene id: 104268:D6200_RS11885
uniprot id: A0A1M5DE56
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

104268:D6200 RS01375
gene id: 104268:D6200_RS01375
uniprot id: A0A1M5C198
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

104268:D6200 RS00520
gene id: 104268:D6200_RS00520
uniprot id: A0A1M5C9Y0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

104268:D6200 RS11490
gene id: 104268:D6200_RS11490
uniprot id: A0A1M5DHM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS11590
gene id: 104268:D6200_RS11590
uniprot id: A0A1M5DHA7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

104268:D6200 RS05350
gene id: 104268:D6200_RS05350
uniprot id: A0A1M5FC24
names: Similarity
messages: Belongs to the ParB family.

104268:D6200 RS07870
gene id: 104268:D6200_RS07870
uniprot id: A0A1M5HJE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

104268:D6200 RS08030
gene id: 104268:D6200_RS08030
uniprot id: A0A1M5H037
names: Similarity
messages: Belongs to the SusD family.

104268:D6200 RS13405
gene id: 104268:D6200_RS13405
uniprot id: A0A1M5CX98
names: Similarity
messages: Belongs to the proline racemase family.

104268:D6200 RS04620
gene id: 104268:D6200_RS04620
uniprot id: A0A1M5F2H1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

104268:D6200 RS11210
gene id: 104268:D6200_RS11210
uniprot id: A0A1M5DKF6
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

104268:D6200 RS02640
gene id: 104268:D6200_RS02640
uniprot id: A0A1M5FSR5
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

104268:D6200 RS10655
gene id: 104268:D6200_RS10655
uniprot id: A0A1M5DRI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

104268:D6200 RS11675
gene id: 104268:D6200_RS11675
uniprot id: A0A1M5DGH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

104268:D6200 RS10145
gene id: 104268:D6200_RS10145
uniprot id: A0A1M5DXT1
names: Similarity
messages: Belongs to the DinB family.

104268:D6200 RS13680
gene id: 104268:D6200_RS13680
uniprot id: A0A1M5CU45
names: Similarity
messages: Belongs to the thioredoxin family.

104268:D6200 RS14130
gene id: 104268:D6200_RS14130
uniprot id: A0A1M5CPX7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

104268:D6200 RS06305
gene id: 104268:D6200_RS06305
uniprot id: A0A1M5HP69
names: Similarity
messages: Belongs to the AAA ATPase family.

104268:D6200 RS00680
gene id: 104268:D6200_RS00680
uniprot id: A0A1M5C7E2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

104268:D6200 RS12085
gene id: 104268:D6200_RS12085
uniprot id: A0A1M5DB70
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS01740
gene id: 104268:D6200_RS01740
uniprot id: A0A1M5G0D3
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

104268:D6200 RS14980
gene id: 104268:D6200_RS14980
uniprot id: A0A1M5CF35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

104268:D6200 RS08685
gene id: 104268:D6200_RS08685
uniprot id: A0A1M5GT29
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

104268:D6200 RS09905
gene id: 104268:D6200_RS09905
uniprot id: A0A1M5E058
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

104268:D6200 RS04915
gene id: 104268:D6200_RS04915
uniprot id: A0A1M5F6B4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS02085
gene id: 104268:D6200_RS02085
uniprot id: A0A1M5FWX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS14680
gene id: 104268:D6200_RS14680
uniprot id: A0A1M5CI54
names: Similarity
messages: Belongs to the glutamine synthetase family.

104268:D6200 RS05940
gene id: 104268:D6200_RS05940
uniprot id: A0A1M5FGY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

104268:D6200 RS07215
gene id: 104268:D6200_RS07215
uniprot id: A0A1M5H9K1
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS03380
gene id: 104268:D6200_RS03380
uniprot id: A0A1M5GEF4
names: Similarity
messages: Belongs to the pirin family.

104268:D6200 RS03760
gene id: 104268:D6200_RS03760
uniprot id: A0A1M5GI95
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

104268:D6200 RS09295
gene id: 104268:D6200_RS09295
uniprot id: A0A1M5E7J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

104268:D6200 RS06460
gene id: 104268:D6200_RS06460
uniprot id: A0A1M5HMP9
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS09930
gene id: 104268:D6200_RS09930
uniprot id: A0A1M5E0A5
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS10055
gene id: 104268:D6200_RS10055
uniprot id: A0A1M5DYZ3
names: Similarity
messages: Belongs to the aspartokinase family.

104268:D6200 RS12760
gene id: 104268:D6200_RS12760
uniprot id: A0A1M5D4C5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

104268:D6200 RS11135
gene id: 104268:D6200_RS11135
uniprot id: A0A1M5DLM1
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS14585
gene id: 104268:D6200_RS14585
uniprot id: A0A1M5CIL9
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

104268:D6200 RS15225
gene id: 104268:D6200_RS15225
uniprot id: A0A1M5CCT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

104268:D6200 RS11525
gene id: 104268:D6200_RS11525
uniprot id: A0A1M5DHE6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS05550
gene id: 104268:D6200_RS05550
uniprot id: A0A1M5FCS8
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

104268:D6200 RS00210
gene id: 104268:D6200_RS00210
uniprot id: A0A1M5CCP0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS12590
gene id: 104268:D6200_RS12590
uniprot id: A0A1M5D691
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

104268:D6200 RS08450
gene id: 104268:D6200_RS08450
uniprot id: A0A1M5GVH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS13765
gene id: 104268:D6200_RS13765
uniprot id: A0A1M5CTC1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

104268:D6200 RS12010
gene id: 104268:D6200_RS12010
uniprot id: A0A1M5DBU0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

104268:D6200 RS13820
gene id: 104268:D6200_RS13820
uniprot id: A0A1M5CSK4
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS08460
gene id: 104268:D6200_RS08460
uniprot id: A0A1M5GVE0
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

104268:D6200 RS03090
gene id: 104268:D6200_RS03090
uniprot id: A0A1M5GBW5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

104268:D6200 RS15145
gene id: 104268:D6200_RS15145
uniprot id: A0A1M5CDF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

104268:D6200 RS01915
gene id: 104268:D6200_RS01915
uniprot id: A0A1M5FYU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

104268:D6200 RS05300
gene id: 104268:D6200_RS05300
uniprot id: A0A1M5FAF5
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

104268:D6200 RS14730
gene id: 104268:D6200_RS14730
uniprot id: A0A1M5CHE3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

104268:D6200 RS09310
gene id: 104268:D6200_RS09310
uniprot id: A0A1M5E7G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

104268:D6200 RS15015
gene id: 104268:D6200_RS15015
uniprot id: A0A1M5CEP1
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

104268:D6200 RS07580
gene id: 104268:D6200_RS07580
uniprot id: A0A1M5HG99
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS02300
gene id: 104268:D6200_RS02300
uniprot id: A0A1M5FVT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

104268:D6200 RS13855
gene id: 104268:D6200_RS13855
uniprot id: A0A1M5CS24
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

104268:D6200 RS03815
gene id: 104268:D6200_RS03815
uniprot id: A0A1M5GIX0
names: Similarity
messages: Belongs to the Dps family.

104268:D6200 RS02685
gene id: 104268:D6200_RS02685
uniprot id: A0A1M5FRN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

104268:D6200 RS07980
gene id: 104268:D6200_RS07980
uniprot id: A0A1M5H0M6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

104268:D6200 RS14325
gene id: 104268:D6200_RS14325
uniprot id: A0A1M5CMK6
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS02035
gene id: 104268:D6200_RS02035
uniprot id: A0A1M5FXI0
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

104268:D6200 RS10435
gene id: 104268:D6200_RS10435
uniprot id: A0A1M5DU73
names: Similarity
messages: Belongs to the DEAD box helicase family.

104268:D6200 RS10000
gene id: 104268:D6200_RS10000
uniprot id: A0A1M5DZ57
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS02235
gene id: 104268:D6200_RS02235
uniprot id: A0A1M5FVX7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

104268:D6200 RS00915
gene id: 104268:D6200_RS00915
uniprot id: A0A1M5C5D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

104268:D6200 RS12055
gene id: 104268:D6200_RS12055
uniprot id: A0A1M5DCB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS13905
gene id: 104268:D6200_RS13905
uniprot id: A0A1M5CRG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

104268:D6200 RS09840
gene id: 104268:D6200_RS09840
uniprot id: A0A1M5E100
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS03970
gene id: 104268:D6200_RS03970
uniprot id: A0A1M5GKP5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

104268:D6200 RS08480
gene id: 104268:D6200_RS08480
uniprot id: A0A1M5GV77
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

104268:D6200 RS09935
gene id: 104268:D6200_RS09935
uniprot id: A0A1M5E029
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

104268:D6200 RS10040
gene id: 104268:D6200_RS10040
uniprot id: A0A1M5DYR9
names: Similarity
messages: Belongs to the SCO1/2 family.

104268:D6200 RS11065
gene id: 104268:D6200_RS11065
uniprot id: A0A1M5DLX9
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

104268:D6200 RS07300
gene id: 104268:D6200_RS07300
uniprot id: A0A1M5HB63
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

104268:D6200 RS04555
gene id: 104268:D6200_RS04555
uniprot id: A0A1M5F1S5
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS01540
gene id: 104268:D6200_RS01540
uniprot id: A0A1M5G2N1
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

104268:D6200 RS11500
gene id: 104268:D6200_RS11500
uniprot id: A0A1M5DHI5
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

104268:D6200 RS05540
gene id: 104268:D6200_RS05540
uniprot id: A0A1M5FDV5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

104268:D6200 RS01190
gene id: 104268:D6200_RS01190
uniprot id: A0A1M5C2T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS03330
gene id: 104268:D6200_RS03330
uniprot id: A0A1M5GDV5
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

104268:D6200 RS11815
gene id: 104268:D6200_RS11815
uniprot id: A0A1M5DDQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

104268:D6200 RS00085
gene id: 104268:D6200_RS00085
uniprot id: A0A1M5CCT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

104268:D6200 RS11180
gene id: 104268:D6200_RS11180
uniprot id: A0A1M5DKR2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

104268:D6200 RS02265
gene id: 104268:D6200_RS02265
uniprot id: A0A1M5FVF6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

104268:D6200 RS11515
gene id: 104268:D6200_RS11515
uniprot id: A0A1M5DH72
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS12775
gene id: 104268:D6200_RS12775
uniprot id: A0A1M5D4L2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS00045
gene id: 104268:D6200_RS00045
uniprot id: A0A1M5CD60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

104268:D6200 RS00125
gene id: 104268:D6200_RS00125
uniprot id: A0A1M5CCN5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

104268:D6200 RS15185
gene id: 104268:D6200_RS15185
uniprot id: A0A1M5CD60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

104268:D6200 RS00980
gene id: 104268:D6200_RS00980
uniprot id: A0A1M5C4V4
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS15055
gene id: 104268:D6200_RS15055
uniprot id: A0A1M5CEB4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

104268:D6200 RS02605
gene id: 104268:D6200_RS02605
uniprot id: A0A1M5FS15
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

104268:D6200 RS12820
gene id: 104268:D6200_RS12820
uniprot id: A0A1M5D3I8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

104268:D6200 RS08960
gene id: 104268:D6200_RS08960
uniprot id: A0A1M5EBX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

104268:D6200 RS00135
gene id: 104268:D6200_RS00135
uniprot id: A0A1M5CCE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

104268:D6200 RS14115
gene id: 104268:D6200_RS14115
uniprot id: A0A1M5CP94
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

104268:D6200 RS05985
gene id: 104268:D6200_RS05985
uniprot id: A0A1M5FI68
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

104268:D6200 RS08395
gene id: 104268:D6200_RS08395
uniprot id: A0A1M5GW32
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

104268:D6200 RS03050
gene id: 104268:D6200_RS03050
uniprot id: A0A1M5GAT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

104268:D6200 RS12840
gene id: 104268:D6200_RS12840
uniprot id: A0A1M5D448
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

104268:D6200 RS08125
gene id: 104268:D6200_RS08125
uniprot id: A0A1M5GYY4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

104268:D6200 RS09775
gene id: 104268:D6200_RS09775
uniprot id: A0A1M5E1N5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

104268:D6200 RS08515
gene id: 104268:D6200_RS08515
uniprot id: A0A1M5GUS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

104268:D6200 RS14435
gene id: 104268:D6200_RS14435
uniprot id: A0A1M5CKG3
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

104268:D6200 RS01450
gene id: 104268:D6200_RS01450
uniprot id: A0A1M5C0B5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

104268:D6200 RS03540
gene id: 104268:D6200_RS03540
uniprot id: A0A1M5GFZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

104268:D6200 RS15140
gene id: 104268:D6200_RS15140
uniprot id: A0A1M5CDJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

104268:D6200 RS07890
gene id: 104268:D6200_RS07890
uniprot id: A0A1M5HJN2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS09300
gene id: 104268:D6200_RS09300
uniprot id: A0A1M5E7S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

104268:D6200 RS12795
gene id: 104268:D6200_RS12795
uniprot id: A0A1M5D4D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

104268:D6200 RS09375
gene id: 104268:D6200_RS09375
uniprot id: A0A1M5E6P9
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

104268:D6200 RS05270
gene id: 104268:D6200_RS05270
uniprot id: A0A1M5FA82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

104268:D6200 RS09155
gene id: 104268:D6200_RS09155
uniprot id: A0A1M5E9S1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

104268:D6200 RS14260
gene id: 104268:D6200_RS14260
uniprot id: A0A1M5CMG1
names: Similarity
messages: Belongs to the NAPRTase family.

104268:D6200 RS09275
gene id: 104268:D6200_RS09275
uniprot id: A0A1M5E7M4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

104268:D6200 RS00010
gene id: 104268:D6200_RS00010
uniprot id: A0A1M5CDJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

104268:D6200 RS00070
gene id: 104268:D6200_RS00070
uniprot id: A0A1M5CCZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

104268:D6200 RS05085
gene id: 104268:D6200_RS05085
uniprot id: A0A1M5F7W8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

104268:D6200 RS03995
gene id: 104268:D6200_RS03995
uniprot id: A0A1M5GL08
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

104268:D6200 RS00215
gene id: 104268:D6200_RS00215
uniprot id: A0A1M5CBT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

104268:D6200 RS00585
gene id: 104268:D6200_RS00585
uniprot id: A0A1M5C8T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

104268:D6200 RS06355
gene id: 104268:D6200_RS06355
uniprot id: A0A1M5HNP3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

104268:D6200 RS05135
gene id: 104268:D6200_RS05135
uniprot id: A0A1M5F8G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

104268:D6200 RS05910
gene id: 104268:D6200_RS05910
uniprot id: A0A1M5FHH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

104268:D6200 RS00600
gene id: 104268:D6200_RS00600
uniprot id: A0A1M5C8A7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS12895
gene id: 104268:D6200_RS12895
uniprot id: A0A1M5D2V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

104268:D6200 RS03465
gene id: 104268:D6200_RS03465
uniprot id: A0A1M5GFA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

104268:D6200 RS15135
gene id: 104268:D6200_RS15135
uniprot id: A0A1M5CEI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

104268:D6200 RS03905
gene id: 104268:D6200_RS03905
uniprot id: A0A1M5GJV0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

104268:D6200 RS08810
gene id: 104268:D6200_RS08810
uniprot id: A0A1M5GRH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

104268:D6200 RS13960
gene id: 104268:D6200_RS13960
uniprot id: A0A1M5CQY3
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

104268:D6200 RS09595
gene id: 104268:D6200_RS09595
uniprot id: A0A1M5E3Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS10755
gene id: 104268:D6200_RS10755
uniprot id: A0A1M5DQN3
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

104268:D6200 RS14415
gene id: 104268:D6200_RS14415
uniprot id: A0A1M5CKP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

104268:D6200 RS12410
gene id: 104268:D6200_RS12410
uniprot id: A0A1M5D896
names: Similarity
messages: Belongs to the peptidase S41A family.

104268:D6200 RS11520
gene id: 104268:D6200_RS11520
uniprot id: A0A1M5DHB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

104268:D6200 RS01215
gene id: 104268:D6200_RS01215
uniprot id: A0A1M5C2T0
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

104268:D6200 RS02370
gene id: 104268:D6200_RS02370
uniprot id: A0A1M5FUH8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

104268:D6200 RS12585
gene id: 104268:D6200_RS12585
uniprot id: A0A1M5D6R1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

104268:D6200 RS06055
gene id: 104268:D6200_RS06055
uniprot id: A0A1M5FI63
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

104268:D6200 RS05640
gene id: 104268:D6200_RS05640
uniprot id: A0A1M5FDD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

104268:D6200 RS04945
gene id: 104268:D6200_RS04945
uniprot id: A0A1M5F6M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

104268:D6200 RS13585
gene id: 104268:D6200_RS13585
uniprot id: A0A1M5CV52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS00195
gene id: 104268:D6200_RS00195
uniprot id: A0A1M5CC00
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

104268:D6200 RS04310
gene id: 104268:D6200_RS04310
uniprot id: A0A1M5EZ21
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

104268:D6200 RS12600
gene id: 104268:D6200_RS12600
uniprot id: A0A1M5D6K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

104268:D6200 RS04955
gene id: 104268:D6200_RS04955
uniprot id: A0A1M5F7Y0
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS08610
gene id: 104268:D6200_RS08610
uniprot id: A0A1M5GTR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

104268:D6200 RS02015
gene id: 104268:D6200_RS02015
uniprot id: A0A1M5FXW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

104268:D6200 RS00925
gene id: 104268:D6200_RS00925
uniprot id: A0A1M5C685
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

104268:D6200 RS05255
gene id: 104268:D6200_RS05255
uniprot id: A0A1M5F9Q1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

104268:D6200 RS06835
gene id: 104268:D6200_RS06835
uniprot id: A0A1M5H5E2
names: Similarity
messages: Belongs to the peptidase C1 family.

104268:D6200 RS07310
gene id: 104268:D6200_RS07310
uniprot id: A0A1M5HB15
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

104268:D6200 RS00080
gene id: 104268:D6200_RS00080
uniprot id: A0A1M5CDA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

104268:D6200 RS01060
gene id: 104268:D6200_RS01060
uniprot id: A0A1M5C400
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS12065
gene id: 104268:D6200_RS12065
uniprot id: A0A1M5DB88
names: Similarity
messages: Belongs to the DtxR/MntR family.

104268:D6200 RS10640
gene id: 104268:D6200_RS10640
uniprot id: A0A1M5DRN5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

104268:D6200 RS01515
gene id: 104268:D6200_RS01515
uniprot id: A0A1M5G2S1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

104268:D6200 RS14675
gene id: 104268:D6200_RS14675
uniprot id: A0A1M5CHP3
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS04625
gene id: 104268:D6200_RS04625
uniprot id: A0A1M5F2R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

104268:D6200 RS11970
gene id: 104268:D6200_RS11970
uniprot id: A0A1M5DD71
names: Similarity
messages: Belongs to the universal stress protein A family.

104268:D6200 RS07025
gene id: 104268:D6200_RS07025
uniprot id: A0A1M5H7L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

104268:D6200 RS01910
gene id: 104268:D6200_RS01910
uniprot id: A0A1M5FZ36
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

104268:D6200 RS11620
gene id: 104268:D6200_RS11620
uniprot id: A0A1M5DG57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS02010
gene id: 104268:D6200_RS02010
uniprot id: A0A1M5FYR3
names: Similarity
messages: Belongs to the arginase family.

104268:D6200 RS06655
gene id: 104268:D6200_RS06655
uniprot id: A0A1M5HTC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS08145
gene id: 104268:D6200_RS08145
uniprot id: A0A1M5GZ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

104268:D6200 RS04420
gene id: 104268:D6200_RS04420
uniprot id: A0A1M5F145
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

104268:D6200 RS08155
gene id: 104268:D6200_RS08155
uniprot id: A0A1M5GZ14
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

104268:D6200 RS02245
gene id: 104268:D6200_RS02245
uniprot id: A0A1M5FWC9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS12380
gene id: 104268:D6200_RS12380
uniprot id: A0A1M5D9L8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

104268:D6200 RS08740
gene id: 104268:D6200_RS08740
uniprot id: A0A1M5GS95
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

104268:D6200 RS10975
gene id: 104268:D6200_RS10975
uniprot id: A0A1M5DNC2
names: Similarity
messages: Belongs to the peptidase M4 family.

104268:D6200 RS14815
gene id: 104268:D6200_RS14815
uniprot id: A0A1M5CGH5
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

104268:D6200 RS07105
gene id: 104268:D6200_RS07105
uniprot id: A0A1M5H879
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

104268:D6200 RS10360
gene id: 104268:D6200_RS10360
uniprot id: A0A1M5DUR1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

104268:D6200 RS01605
gene id: 104268:D6200_RS01605
uniprot id: A0A1M5G202
names: Similarity
messages: Belongs to the UPF0246 family.

104268:D6200 RS10085
gene id: 104268:D6200_RS10085
uniprot id: A0A1M5DYF5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

104268:D6200 RS09450
gene id: 104268:D6200_RS09450
uniprot id: A0A1M5E604
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

104268:D6200 RS10620
gene id: 104268:D6200_RS10620
uniprot id: A0A1M5DRZ2
names: Similarity
messages: Belongs to the peptidase M13 family.

104268:D6200 RS08670
gene id: 104268:D6200_RS08670
uniprot id: A0A1M5GSZ1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

104268:D6200 RS01365
gene id: 104268:D6200_RS01365
uniprot id: A0A1M5C114
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS03120
gene id: 104268:D6200_RS03120
uniprot id: A0A1M5GBL1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

104268:D6200 RS13840
gene id: 104268:D6200_RS13840
uniprot id: A0A1M5CTC9
names: Similarity
messages: Belongs to the EPSP synthase family.

104268:D6200 RS06465
gene id: 104268:D6200_RS06465
uniprot id: A0A1M5HML4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

104268:D6200 RS14350
gene id: 104268:D6200_RS14350
uniprot id: A0A1M5CL99
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

104268:D6200 RS11060
gene id: 104268:D6200_RS11060
uniprot id: A0A1M5DMA1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

104268:D6200 RS04290
gene id: 104268:D6200_RS04290
uniprot id: A0A1M5EZ01
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

104268:D6200 RS00020
gene id: 104268:D6200_RS00020
uniprot id: A0A1M5CDL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

104268:D6200 RS03130
gene id: 104268:D6200_RS03130
uniprot id: A0A1M5GBS4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

104268:D6200 RS07200
gene id: 104268:D6200_RS07200
uniprot id: A0A1M5H9J7
names: Similarity
messages: Belongs to the nitroreductase family.

104268:D6200 RS01390
gene id: 104268:D6200_RS01390
uniprot id: A0A1M5C130
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

104268:D6200 RS10200
gene id: 104268:D6200_RS10200
uniprot id: A0A1M5DX09
names: Similarity
messages: Belongs to the ribF family.

104268:D6200 RS12320
gene id: 104268:D6200_RS12320
uniprot id: A0A1M5D9H1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

104268:D6200 RS00945
gene id: 104268:D6200_RS00945
uniprot id: A0A1M5C515
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS00155
gene id: 104268:D6200_RS00155
uniprot id: A0A1M5CCB3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

104268:D6200 RS05685
gene id: 104268:D6200_RS05685
uniprot id: A0A1M5FDT1
names: Similarity
messages: Belongs to the glutamate synthase family.

104268:D6200 RS08615
gene id: 104268:D6200_RS08615
uniprot id: A0A1M5GTH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS02405
gene id: 104268:D6200_RS02405
uniprot id: A0A1M5FTV9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

104268:D6200 RS10835
gene id: 104268:D6200_RS10835
uniprot id: A0A1M5DPF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

104268:D6200 RS08425
gene id: 104268:D6200_RS08425
uniprot id: A0A1M5GVR6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

104268:D6200 RS15050
gene id: 104268:D6200_RS15050
uniprot id: A0A1M5CE77
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS05325
gene id: 104268:D6200_RS05325
uniprot id: A0A1M5FAK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

104268:D6200 RS14180
gene id: 104268:D6200_RS14180
uniprot id: A0A1M5CNS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

104268:D6200 RS05655
gene id: 104268:D6200_RS05655
uniprot id: A0A1M5FDK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

104268:D6200 RS01725
gene id: 104268:D6200_RS01725
uniprot id: A0A1M5G0N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

104268:D6200 RS04655
gene id: 104268:D6200_RS04655
uniprot id: A0A1M5F3F5
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS03895
gene id: 104268:D6200_RS03895
uniprot id: A0A1M5GJX3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

104268:D6200 RS11225
gene id: 104268:D6200_RS11225
uniprot id: A0A1M5DK72
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS03205
gene id: 104268:D6200_RS03205
uniprot id: A0A1M5GD60
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

104268:D6200 RS05555
gene id: 104268:D6200_RS05555
uniprot id: A0A1M5FDV4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

104268:D6200 RS00785
gene id: 104268:D6200_RS00785
uniprot id: A0A1M5C6J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

104268:D6200 RS13410
gene id: 104268:D6200_RS13410
uniprot id: A0A1M5CX17
names: Similarity
messages: Belongs to the peptidase M24B family.

104268:D6200 RS10025
gene id: 104268:D6200_RS10025
uniprot id: A0A1M5DZ76
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

104268:D6200 RS08525
gene id: 104268:D6200_RS08525
uniprot id: A0A1M5GUP8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

104268:D6200 RS02290
gene id: 104268:D6200_RS02290
uniprot id: A0A1M5FV23
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

104268:D6200 RS00940
gene id: 104268:D6200_RS00940
uniprot id: A0A1M5C5C2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

104268:D6200 RS01335
gene id: 104268:D6200_RS01335
uniprot id: A0A1M5C1L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

104268:D6200 RS06360
gene id: 104268:D6200_RS06360
uniprot id: A0A1M5HNM5
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

104268:D6200 RS12725
gene id: 104268:D6200_RS12725
uniprot id: A0A1M5D5L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

104268:D6200 RS11380
gene id: 104268:D6200_RS11380
uniprot id: A0A1M5DIG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

104268:D6200 RS03525
gene id: 104268:D6200_RS03525
uniprot id: A0A1M5GFX5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

104268:D6200 RS08130
gene id: 104268:D6200_RS08130
uniprot id: A0A1M5GYY6
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS07825
gene id: 104268:D6200_RS07825
uniprot id: A0A1M5HJD3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

104268:D6200 RS11030
gene id: 104268:D6200_RS11030
uniprot id: A0A1M5DMI1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

104268:D6200 RS07280
gene id: 104268:D6200_RS07280
uniprot id: A0A1M5HAG7
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS14305
gene id: 104268:D6200_RS14305
uniprot id: A0A1M5CM01
names: Similarity
messages: Belongs to the Nudix hydrolase family.

104268:D6200 RS04000
gene id: 104268:D6200_RS04000
uniprot id: A0A1M5GLM6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

104268:D6200 RS07985
gene id: 104268:D6200_RS07985
uniprot id: A0A1M5H0H4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

104268:D6200 RS11075
gene id: 104268:D6200_RS11075
uniprot id: A0A1M5DLW3
names: Cofactor
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

104268:D6200 RS00545
gene id: 104268:D6200_RS00545
uniprot id: A0A1M5C908
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS00055
gene id: 104268:D6200_RS00055
uniprot id: A0A1M5CD30
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

104268:D6200 RS07855
gene id: 104268:D6200_RS07855
uniprot id: A0A1M5HJE8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

104268:D6200 RS15230
gene id: 104268:D6200_RS15230
uniprot id: A0A1M5CCV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

104268:D6200 RS12645
gene id: 104268:D6200_RS12645
uniprot id: A0A1M5D628
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

104268:D6200 RS13575
gene id: 104268:D6200_RS13575
uniprot id: A0A1M5CVE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

104268:D6200 RS15090
gene id: 104268:D6200_RS15090
uniprot id: A0A1M5CE49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

104268:D6200 RS05110
gene id: 104268:D6200_RS05110
uniprot id: A0A1M5F9L3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS14735
gene id: 104268:D6200_RS14735
uniprot id: A0A1M5CH95
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

104268:D6200 RS08805
gene id: 104268:D6200_RS08805
uniprot id: A0A1M5GRH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

104268:D6200 RS02105
gene id: 104268:D6200_RS02105
uniprot id: A0A1M5FX16
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

104268:D6200 RS09530
gene id: 104268:D6200_RS09530
uniprot id: A0A1M5E4N4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS11770
gene id: 104268:D6200_RS11770
uniprot id: A0A1M5DFD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS05625
gene id: 104268:D6200_RS05625
uniprot id: A0A1M5FDG6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS08620
gene id: 104268:D6200_RS08620
uniprot id: A0A1M5GTD0
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS05065
gene id: 104268:D6200_RS05065
uniprot id: A0A1M5F7X7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

104268:D6200 RS06980
gene id: 104268:D6200_RS06980
uniprot id: A0A1M5H6Z2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

104268:D6200 RS12515
gene id: 104268:D6200_RS12515
uniprot id: A0A1M5D7J9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

104268:D6200 RS08400
gene id: 104268:D6200_RS08400
uniprot id: A0A1M5GVW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS14300
gene id: 104268:D6200_RS14300
uniprot id: A0A1M5CLS9
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

104268:D6200 RS08405
gene id: 104268:D6200_RS08405
uniprot id: A0A1M5GVY8
names: Similarity
messages: Belongs to the MreC family.

104268:D6200 RS00040
gene id: 104268:D6200_RS00040
uniprot id: A0A1M5CD98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

104268:D6200 RS10305
gene id: 104268:D6200_RS10305
uniprot id: A0A1M5DVU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

104268:D6200 RS06365
gene id: 104268:D6200_RS06365
uniprot id: A0A1M5HNG2
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS03910
gene id: 104268:D6200_RS03910
uniprot id: A0A1M5GK11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

104268:D6200 RS05115
gene id: 104268:D6200_RS05115
uniprot id: A0A1M5F8H9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS09175
gene id: 104268:D6200_RS09175
uniprot id: A0A1M5E9L4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

104268:D6200 RS01420
gene id: 104268:D6200_RS01420
uniprot id: A0A1M5C0Y7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

104268:D6200 RS09500
gene id: 104268:D6200_RS09500
uniprot id: A0A1M5E5H1
names: Similarity
messages: Belongs to the SufE family.

104268:D6200 RS03945
gene id: 104268:D6200_RS03945
uniprot id: A0A1M5GL12
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

104268:D6200 RS08080
gene id: 104268:D6200_RS08080
uniprot id: A0A1M5GZH1
names: Similarity
messages: Belongs to the peptidase S41A family.

104268:D6200 RS13175
gene id: 104268:D6200_RS13175
uniprot id: A0A1M5CZD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS02775
gene id: 104268:D6200_RS02775
uniprot id: A0A1M5FQQ2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

104268:D6200 RS14425
gene id: 104268:D6200_RS14425
uniprot id: A0A1M5CLD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

104268:D6200 RS02260
gene id: 104268:D6200_RS02260
uniprot id: A0A1M5FW88
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

104268:D6200 RS14375
gene id: 104268:D6200_RS14375
uniprot id: A0A1M5CL54
names: Similarity
messages: Belongs to the asparagine synthetase family.

104268:D6200 RS05055
gene id: 104268:D6200_RS05055
uniprot id: A0A1M5F7X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

104268:D6200 RS07885
gene id: 104268:D6200_RS07885
uniprot id: A0A1M5HJT3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

104268:D6200 RS07150
gene id: 104268:D6200_RS07150
uniprot id: A0A1M5H8W8
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS00160
gene id: 104268:D6200_RS00160
uniprot id: A0A1M5CC63
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

104268:D6200 RS08060
gene id: 104268:D6200_RS08060
uniprot id: A0A1M5H0F9
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

104268:D6200 RS01590
gene id: 104268:D6200_RS01590
uniprot id: A0A1M5G271
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

104268:D6200 RS00890
gene id: 104268:D6200_RS00890
uniprot id: A0A1M5C5L4
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS00280
gene id: 104268:D6200_RS00280
uniprot id: A0A1M5CC30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

104268:D6200 RS03270
gene id: 104268:D6200_RS03270
uniprot id: A0A1M5GDX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

104268:D6200 RS07785
gene id: 104268:D6200_RS07785
uniprot id: A0A1M5HIF5
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

104268:D6200 RS13535
gene id: 104268:D6200_RS13535
uniprot id: A0A1M5CVT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

104268:D6200 RS11020
gene id: 104268:D6200_RS11020
uniprot id: A0A1M5DMM2
names: Similarity
messages: Belongs to the peptidase S41A family.

104268:D6200 RS00015
gene id: 104268:D6200_RS00015
uniprot id: A0A1M5CDE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

104268:D6200 RS15165
gene id: 104268:D6200_RS15165
uniprot id: A0A1M5CDH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

104268:D6200 RS13375
gene id: 104268:D6200_RS13375
uniprot id: A0A1M5CXF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

104268:D6200 RS01630
gene id: 104268:D6200_RS01630
uniprot id: A0A1M5G1K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

104268:D6200 RS00860
gene id: 104268:D6200_RS00860
uniprot id: A0A1M5C5W2
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

104268:D6200 RS14250
gene id: 104268:D6200_RS14250
uniprot id: A0A1M5CMK8
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

104268:D6200 RS05870
gene id: 104268:D6200_RS05870
uniprot id: A0A1M5FG62
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

104268:D6200 RS00090
gene id: 104268:D6200_RS00090
uniprot id: A0A1M5CCV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

104268:D6200 RS02075
gene id: 104268:D6200_RS02075
uniprot id: A0A1M5FXB8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

104268:D6200 RS13430
gene id: 104268:D6200_RS13430
uniprot id: A0A1M5CWS7
names: Similarity
messages: Belongs to the DapA family.

104268:D6200 RS07895
gene id: 104268:D6200_RS07895
uniprot id: A0A1M5HJR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

104268:D6200 RS01005
gene id: 104268:D6200_RS01005
uniprot id: A0A1M5C4H1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

104268:D6200 RS06380
gene id: 104268:D6200_RS06380
uniprot id: A0A1M5HNC5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

104268:D6200 RS13800
gene id: 104268:D6200_RS13800
uniprot id: A0A1M5CST9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

104268:D6200 RS09845
gene id: 104268:D6200_RS09845
uniprot id: A0A1M5E126
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

104268:D6200 RS07970
gene id: 104268:D6200_RS07970
uniprot id: A0A1M5H0H2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS09215
gene id: 104268:D6200_RS09215
uniprot id: A0A1M5E928
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

104268:D6200 RS05155
gene id: 104268:D6200_RS05155
uniprot id: A0A1M5F8W9
names: Subcellular Location Annotation
messages: Secreted

104268:D6200 RS04005
gene id: 104268:D6200_RS04005
uniprot id: A0A1M5GL75
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.

104268:D6200 RS04685
gene id: 104268:D6200_RS04685
uniprot id: A0A1M5F4E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

104268:D6200 RS06605
gene id: 104268:D6200_RS06605
uniprot id: A0A1M5HSR1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

104268:D6200 RS13555
gene id: 104268:D6200_RS13555
uniprot id: A0A1M5CVF4
names: Similarity
messages: Belongs to the NAD synthetase family.

104268:D6200 RS03320
gene id: 104268:D6200_RS03320
uniprot id: A0A1M5GDW6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

104268:D6200 RS09725
gene id: 104268:D6200_RS09725
uniprot id: A0A1M5E2D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

104268:D6200 RS15220
gene id: 104268:D6200_RS15220
uniprot id: A0A1M5CDA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

104268:D6200 RS04935
gene id: 104268:D6200_RS04935
uniprot id: A0A1M5F6J3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

104268:D6200 RS08700
gene id: 104268:D6200_RS08700
uniprot id: A0A1M5GSG7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

104268:D6200 RS10295
gene id: 104268:D6200_RS10295
uniprot id: A0A1M5DW11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

104268:D6200 RS03335
gene id: 104268:D6200_RS03335
uniprot id: A0A1M5GDU0
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

104268:D6200 RS02180
gene id: 104268:D6200_RS02180
uniprot id: A0A1M5FW18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

104268:D6200 RS02365
gene id: 104268:D6200_RS02365
uniprot id: A0A1M5FUH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

104268:D6200 RS09985
gene id: 104268:D6200_RS09985
uniprot id: A0A1M5DZU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

104268:D6200 RS11630
gene id: 104268:D6200_RS11630
uniprot id: A0A1M5DGY7
names: Similarity
messages: Belongs to the MoaD family.

104268:D6200 RS01645
gene id: 104268:D6200_RS01645
uniprot id: A0A1M5G1J0
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

104268:D6200 RS12430
gene id: 104268:D6200_RS12430
uniprot id: A0A1M5D8A7
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

104268:D6200 RS05360
gene id: 104268:D6200_RS05360
uniprot id: A0A1M5FCB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

104268:D6200 RS15060
gene id: 104268:D6200_RS15060
uniprot id: A0A1M5CE73
names: Similarity
messages: Belongs to the UPF0758 family.

104268:D6200 RS07010
gene id: 104268:D6200_RS07010
uniprot id: A0A1M5H7G1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

104268:D6200 RS03095
gene id: 104268:D6200_RS03095
uniprot id: A0A1M5GB69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

104268:D6200 RS02680
gene id: 104268:D6200_RS02680
uniprot id: A0A1M5FRQ0
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

104268:D6200 RS07545
gene id: 104268:D6200_RS07545
uniprot id: A0A1M5HFR0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

104268:D6200 RS11285
gene id: 104268:D6200_RS11285
uniprot id: A0A1M5DJP8
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

104268:D6200 RS08575
gene id: 104268:D6200_RS08575
uniprot id: A0A1M5GUU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS07760
gene id: 104268:D6200_RS07760
uniprot id: A0A1M5HI67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

104268:D6200 RS02380
gene id: 104268:D6200_RS02380
uniprot id: A0A1M5FUM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

104268:D6200 RS08815
gene id: 104268:D6200_RS08815
uniprot id: A0A1M5GRP2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

104268:D6200 RS12520
gene id: 104268:D6200_RS12520
uniprot id: A0A1M5D792
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

104268:D6200 RS05060
gene id: 104268:D6200_RS05060
uniprot id: A0A1M5F7Z1
names: Similarity
messages: Belongs to the Dps family.

104268:D6200 RS13845
gene id: 104268:D6200_RS13845
uniprot id: A0A1M5CS66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

104268:D6200 RS06470
gene id: 104268:D6200_RS06470
uniprot id: A0A1M5HMG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

104268:D6200 RS02740
gene id: 104268:D6200_RS02740
uniprot id: A0A1M5FQT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

104268:D6200 RS07875
gene id: 104268:D6200_RS07875
uniprot id: A0A1M5HJF5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

104268:D6200 RS07900
gene id: 104268:D6200_RS07900
uniprot id: A0A1M5HJR6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

104268:D6200 RS02205
gene id: 104268:D6200_RS02205
uniprot id: A0A1M5FVZ3
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

104268:D6200 RS12790
gene id: 104268:D6200_RS12790
uniprot id: A0A1M5D4F2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

104268:D6200 RS03230
gene id: 104268:D6200_RS03230
uniprot id: A0A1M5GCS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

104268:D6200 RS08900
gene id: 104268:D6200_RS08900
uniprot id: A0A1M5ECC0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

104268:D6200 RS05340
gene id: 104268:D6200_RS05340
uniprot id: A0A1M5FB03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

104268:D6200 RS05235
gene id: 104268:D6200_RS05235
uniprot id: A0A1M5FA36
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

104268:D6200 RS11645
gene id: 104268:D6200_RS11645
uniprot id: A0A1M5DG72
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

104268:D6200 RS12120
gene id: 104268:D6200_RS12120
uniprot id: A0A1M5DAV5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

104268:D6200 RS11420
gene id: 104268:D6200_RS11420
uniprot id: A0A1M5DIF2
names: Similarity
messages: Belongs to the IucA/IucC family.

104268:D6200 RS11660
gene id: 104268:D6200_RS11660
uniprot id: A0A1M5DG54
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

104268:D6200 RS03725
gene id: 104268:D6200_RS03725
uniprot id: A0A1M5GHW2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

104268:D6200 RS13580
gene id: 104268:D6200_RS13580
uniprot id: A0A1M5CV81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

104268:D6200 RS12030
gene id: 104268:D6200_RS12030
uniprot id: A0A1M5DBK6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

104268:D6200 RS11625
gene id: 104268:D6200_RS11625
uniprot id: A0A1M5DGF0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

104268:D6200 RS11860
gene id: 104268:D6200_RS11860
uniprot id: A0A1M5DDG7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS09830
gene id: 104268:D6200_RS09830
uniprot id: A0A1M5E141
names: Similarity
messages: Belongs to the SCO1/2 family.

104268:D6200 RS08625
gene id: 104268:D6200_RS08625
uniprot id: A0A1M5GTA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

104268:D6200 RS04815
gene id: 104268:D6200_RS04815
uniprot id: A0A1M5F642
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

104268:D6200 RS00105
gene id: 104268:D6200_RS00105
uniprot id: A0A1M5CCV1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

104268:D6200 RS15160
gene id: 104268:D6200_RS15160
uniprot id: A0A1M5CDL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

104268:D6200 RS15190
gene id: 104268:D6200_RS15190
uniprot id: A0A1M5CD58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

104268:D6200 RS11120
gene id: 104268:D6200_RS11120
uniprot id: A0A1M5DL93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

104268:D6200 RS09130
gene id: 104268:D6200_RS09130
uniprot id: A0A1M5E9Q7
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

104268:D6200 RS07640
gene id: 104268:D6200_RS07640
uniprot id: A0A1M5HGY6
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS09435
gene id: 104268:D6200_RS09435
uniprot id: A0A1M5E5Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

104268:D6200 RS14110
gene id: 104268:D6200_RS14110
uniprot id: A0A1M5CPA7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

104268:D6200 RS01920
gene id: 104268:D6200_RS01920
uniprot id: A0A1M5FZP1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS01525
gene id: 104268:D6200_RS01525
uniprot id: A0A1M5G2Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

104268:D6200 RS04960
gene id: 104268:D6200_RS04960
uniprot id: A0A1M5F803
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS06915
gene id: 104268:D6200_RS06915
uniprot id: A0A1M5H684
names: Similarity
messages: Belongs to the peptidase S9C family.

104268:D6200 RS01905
gene id: 104268:D6200_RS01905
uniprot id: A0A1M5FYQ5
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

104268:D6200 RS07020
gene id: 104268:D6200_RS07020
uniprot id: A0A1M5H7T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

104268:D6200 RS14535
gene id: 104268:D6200_RS14535
uniprot id: A0A1M5CJL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

104268:D6200 RS14280
gene id: 104268:D6200_RS14280
uniprot id: A0A1M5CM85
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

104268:D6200 RS15170
gene id: 104268:D6200_RS15170
uniprot id: A0A1M5CDA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

104268:D6200 RS04875
gene id: 104268:D6200_RS04875
uniprot id: A0A1M5F5W6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

104268:D6200 RS02095
gene id: 104268:D6200_RS02095
uniprot id: A0A1M5FX06
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

104268:D6200 RS07085
gene id: 104268:D6200_RS07085
uniprot id: A0A1M5H8E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

104268:D6200 RS03225
gene id: 104268:D6200_RS03225
uniprot id: A0A1M5GDH7
names: Similarity
messages: Belongs to the AlaDH/PNT family.

104268:D6200 RS02510
gene id: 104268:D6200_RS02510
uniprot id: A0A1M5FU14
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

104268:D6200 RS14935
gene id: 104268:D6200_RS14935
uniprot id: A0A1M5CG99
names: Subunit
messages: Monomer.

104268:D6200 RS03685
gene id: 104268:D6200_RS03685
uniprot id: A0A1M5GHC9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS12780
gene id: 104268:D6200_RS12780
uniprot id: A0A1M5D3V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

104268:D6200 RS02375
gene id: 104268:D6200_RS02375
uniprot id: A0A1M5FV97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

104268:D6200 RS01315
gene id: 104268:D6200_RS01315
uniprot id: A0A1M5C1W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

104268:D6200 RS14470
gene id: 104268:D6200_RS14470
uniprot id: A0A1M5CJY9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS06200
gene id: 104268:D6200_RS06200
uniprot id: A0A1M5HQ55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

104268:D6200 RS13450
gene id: 104268:D6200_RS13450
uniprot id: A0A1M5CX60
names: Similarity
messages: Belongs to the Skp family.

104268:D6200 RS13735
gene id: 104268:D6200_RS13735
uniprot id: A0A1M5CTR5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

104268:D6200 RS07605
gene id: 104268:D6200_RS07605
uniprot id: A0A1M5HGT0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

104268:D6200 RS08115
gene id: 104268:D6200_RS08115
uniprot id: A0A1M5GZ13
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

104268:D6200 RS01765
gene id: 104268:D6200_RS01765
uniprot id: A0A1M5G138
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS08010
gene id: 104268:D6200_RS08010
uniprot id: A0A1M5H0G5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

104268:D6200 RS11165
gene id: 104268:D6200_RS11165
uniprot id: A0A1M5DKR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

104268:D6200 RS01150
gene id: 104268:D6200_RS01150
uniprot id: A0A1M5C3N2
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

104268:D6200 RS09440
gene id: 104268:D6200_RS09440
uniprot id: A0A1M5E5X0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

104268:D6200 RS09210
gene id: 104268:D6200_RS09210
uniprot id: A0A1M5E947
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

104268:D6200 RS09970
gene id: 104268:D6200_RS09970
uniprot id: A0A1M5DZN2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

104268:D6200 RS02670
gene id: 104268:D6200_RS02670
uniprot id: A0A1M5FSE7
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

104268:D6200 RS08510
gene id: 104268:D6200_RS08510
uniprot id: A0A1M5GUK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

104268:D6200 RS05275
gene id: 104268:D6200_RS05275
uniprot id: A0A1M5FA08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

104268:D6200 RS05310
gene id: 104268:D6200_RS05310
uniprot id: A0A1M5FAT8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

104268:D6200 RS01955
gene id: 104268:D6200_RS01955
uniprot id: A0A1M5FYA6
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

104268:D6200 RS04110
gene id: 104268:D6200_RS04110
uniprot id: A0A1M5EX04
names: Similarity
messages: Belongs to the threonine synthase family.

104268:D6200 RS00130
gene id: 104268:D6200_RS00130
uniprot id: A0A1M5CCV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

104268:D6200 RS07610
gene id: 104268:D6200_RS07610
uniprot id: A0A1M5HGL6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS09240
gene id: 104268:D6200_RS09240
uniprot id: A0A1M5E8B6
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

104268:D6200 RS03455
gene id: 104268:D6200_RS03455
uniprot id: A0A1M5GFU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

104268:D6200 RS05045
gene id: 104268:D6200_RS05045
uniprot id: A0A1M5F7F0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

104268:D6200 RS03150
gene id: 104268:D6200_RS03150
uniprot id: A0A1M5GBT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

104268:D6200 RS11080
gene id: 104268:D6200_RS11080
uniprot id: A0A1M5DM29
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS00955
gene id: 104268:D6200_RS00955
uniprot id: A0A1M5C541
names: Similarity
messages: Belongs to the isochorismate synthase family.

104268:D6200 RS13590
gene id: 104268:D6200_RS13590
uniprot id: A0A1M5CV05
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

104268:D6200 RS00605
gene id: 104268:D6200_RS00605
uniprot id: A0A1M5C8M1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

104268:D6200 RS03260
gene id: 104268:D6200_RS03260
uniprot id: A0A1M5GD52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

104268:D6200 RS12435
gene id: 104268:D6200_RS12435
uniprot id: A0A1M5D7Z5
names: Similarity
messages: Belongs to the peptidase S24 family.

104268:D6200 RS11995
gene id: 104268:D6200_RS11995
uniprot id: A0A1M5DCD6
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS12070
gene id: 104268:D6200_RS12070
uniprot id: A0A1M5DBH3
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS14765
gene id: 104268:D6200_RS14765
uniprot id: A0A1M5CGZ1
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

104268:D6200 RS11325
gene id: 104268:D6200_RS11325
uniprot id: A0A1M5DJD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

104268:D6200 RS06805
gene id: 104268:D6200_RS06805
uniprot id: A0A1M5H5T9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS02720
gene id: 104268:D6200_RS02720
uniprot id: A0A1M5FR81
names: Similarity
messages: Belongs to the type IA topoisomerase family.

104268:D6200 RS12560
gene id: 104268:D6200_RS12560
uniprot id: A0A1M5D704
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS10930
gene id: 104268:D6200_RS10930
uniprot id: A0A1M5DNQ8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

104268:D6200 RS10935
gene id: 104268:D6200_RS10935
uniprot id: A0A1M5DNN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

104268:D6200 RS14685
gene id: 104268:D6200_RS14685
uniprot id: A0A1M5CHQ8
names: Similarity
messages: Belongs to the glutamine synthetase family.

104268:D6200 RS07625
gene id: 104268:D6200_RS07625
uniprot id: A0A1M5HGV4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

104268:D6200 RS11745
gene id: 104268:D6200_RS11745
uniprot id: A0A1M5DF42
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

104268:D6200 RS01460
gene id: 104268:D6200_RS01460
uniprot id: A0A1M5C0G9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

104268:D6200 RS04645
gene id: 104268:D6200_RS04645
uniprot id: A0A1M5F3C0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

104268:D6200 RS00035
gene id: 104268:D6200_RS00035
uniprot id: A0A1M5CD81
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

104268:D6200 RS01545
gene id: 104268:D6200_RS01545
uniprot id: A0A1M5G2L0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

104268:D6200 RS05535
gene id: 104268:D6200_RS05535
uniprot id: A0A1M5FCK3
names: Similarity
messages: Belongs to the threonine aldolase family.

104268:D6200 RS08935
gene id: 104268:D6200_RS08935
uniprot id: A0A1M5EC22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

104268:D6200 RS08140
gene id: 104268:D6200_RS08140
uniprot id: A0A1M5GZ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

104268:D6200 RS09755
gene id: 104268:D6200_RS09755
uniprot id: A0A1M5E202
names: Similarity
messages: Belongs to the pyruvate kinase family.

104268:D6200 RS07460
gene id: 104268:D6200_RS07460
uniprot id: A0A1M5HEZ9
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS09315
gene id: 104268:D6200_RS09315
uniprot id: A0A1M5E752
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

104268:D6200 RS03880
gene id: 104268:D6200_RS03880
uniprot id: A0A1M5GJS3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

104268:D6200 RS01535
gene id: 104268:D6200_RS01535
uniprot id: A0A1M5G3N6
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

104268:D6200 RS04105
gene id: 104268:D6200_RS04105
uniprot id: A0A1M5EX35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS13910
gene id: 104268:D6200_RS13910
uniprot id: A0A1M5CRE4
names: Similarity
messages: Belongs to the arginase family.

104268:D6200 RS14690
gene id: 104268:D6200_RS14690
uniprot id: A0A1M5CI17
names: Similarity
messages: Belongs to the CsgA/CsgB family.

104268:D6200 RS07115
gene id: 104268:D6200_RS07115
uniprot id: A0A1M5H8M6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

104268:D6200 RS03105
gene id: 104268:D6200_RS03105
uniprot id: A0A1M5GBB4
names: Similarity
messages: Belongs to the stealth family.

104268:D6200 RS04445
gene id: 104268:D6200_RS04445
uniprot id: A0A1M5F1G6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

104268:D6200 RS13465
gene id: 104268:D6200_RS13465
uniprot id: A0A1M5CWD3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

104268:D6200 RS13550
gene id: 104268:D6200_RS13550
uniprot id: A0A1M5CW87
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

104268:D6200 RS09305
gene id: 104268:D6200_RS09305
uniprot id: A0A1M5E755
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

104268:D6200 RS02980
gene id: 104268:D6200_RS02980
uniprot id: A0A1M5GA02
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

104268:D6200 RS08870
gene id: 104268:D6200_RS08870
uniprot id: A0A1M5ECX2
names: Similarity
messages: Belongs to the SusD family.

104268:D6200 RS05125
gene id: 104268:D6200_RS05125
uniprot id: A0A1M5F8P8
names: Similarity
messages: Belongs to the heat shock protein 90 family.

104268:D6200 RS00535
gene id: 104268:D6200_RS00535
uniprot id: A0A1M5C8Y6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

104268:D6200 RS08635
gene id: 104268:D6200_RS08635
uniprot id: A0A1M5GU88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

104268:D6200 RS02635
gene id: 104268:D6200_RS02635
uniprot id: A0A1M5FS51
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

104268:D6200 RS06840
gene id: 104268:D6200_RS06840
uniprot id: A0A1M5H5P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS11570
gene id: 104268:D6200_RS11570
uniprot id: A0A1M5DHI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

104268:D6200 RS08885
gene id: 104268:D6200_RS08885
uniprot id: A0A1M5ECV8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

104268:D6200 RS12755
gene id: 104268:D6200_RS12755
uniprot id: A0A1M5D4H6
names: Similarity
messages: Belongs to the sigma-54 factor family.

104268:D6200 RS10810
gene id: 104268:D6200_RS10810
uniprot id: A0A1M5DQB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

104268:D6200 RS00265
gene id: 104268:D6200_RS00265
uniprot id: A0A1M5CBD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

104268:D6200 RS03700
gene id: 104268:D6200_RS03700
uniprot id: A0A1M5GHP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

104268:D6200 RS04930
gene id: 104268:D6200_RS04930
uniprot id: A0A1M5F665
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

104268:D6200 RS05230
gene id: 104268:D6200_RS05230
uniprot id: A0A1M5FAZ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

104268:D6200 RS13195
gene id: 104268:D6200_RS13195
uniprot id: A0A1M5CZC1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

104268:D6200 RS11955
gene id: 104268:D6200_RS11955
uniprot id: A0A1M5DCN8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS03020
gene id: 104268:D6200_RS03020
uniprot id: A0A1M5GB74
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS02545
gene id: 104268:D6200_RS02545
uniprot id: A0A1M5FTN7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS05380
gene id: 104268:D6200_RS05380
uniprot id: A0A1M5FBG5
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

104268:D6200 RS03200
gene id: 104268:D6200_RS03200
uniprot id: A0A1M5GCI1
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

104268:D6200 RS14575
gene id: 104268:D6200_RS14575
uniprot id: A0A1M5CIR2
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

104268:D6200 RS11200
gene id: 104268:D6200_RS11200
uniprot id: A0A1M5DKJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS14855
gene id: 104268:D6200_RS14855
uniprot id: A0A1M5CG36
names: Subcellular Location Annotation
messages: Secreted

104268:D6200 RS03100
gene id: 104268:D6200_RS03100
uniprot id: A0A1M5GC09
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

104268:D6200 RS14035
gene id: 104268:D6200_RS14035
uniprot id: A0A1M5CQ11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

104268:D6200 RS12710
gene id: 104268:D6200_RS12710
uniprot id: A0A1M5D4R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

104268:D6200 RS07735
gene id: 104268:D6200_RS07735
uniprot id: A0A1M5HHX8
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

104268:D6200 RS06035
gene id: 104268:D6200_RS06035
uniprot id: A0A1M5FHX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

104268:D6200 RS13695
gene id: 104268:D6200_RS13695
uniprot id: A0A1M5CU69
names: Similarity
messages: Belongs to the peptidase S49 family.

104268:D6200 RS00505
gene id: 104268:D6200_RS00505
uniprot id: A0A1M5C9D6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

104268:D6200 RS02790
gene id: 104268:D6200_RS02790
uniprot id: A0A1M5FQ98
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

104268:D6200 RS03975
gene id: 104268:D6200_RS03975
uniprot id: A0A1M5GKT2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

104268:D6200 RS01555
gene id: 104268:D6200_RS01555
uniprot id: A0A1M5G2B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

104268:D6200 RS14745
gene id: 104268:D6200_RS14745
uniprot id: A0A1M5CHG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

104268:D6200 RS09655
gene id: 104268:D6200_RS09655
uniprot id: A0A1M5E305
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS10495
gene id: 104268:D6200_RS10495
uniprot id: A0A1M5DT48
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS11495
gene id: 104268:D6200_RS11495
uniprot id: A0A1M5DHE2
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

104268:D6200 RS05330
gene id: 104268:D6200_RS05330
uniprot id: A0A1M5FAN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

104268:D6200 RS10710
gene id: 104268:D6200_RS10710
uniprot id: A0A1M5DRE6
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

104268:D6200 RS07830
gene id: 104268:D6200_RS07830
uniprot id: A0A1M5HJ02
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS08055
gene id: 104268:D6200_RS08055
uniprot id: A0A1M5GZP2
names: Similarity
messages: Belongs to the peptidase C40 family.

104268:D6200 RS02320
gene id: 104268:D6200_RS02320
uniprot id: A0A1M5FV10
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS15195
gene id: 104268:D6200_RS15195
uniprot id: A0A1M5CD30
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

104268:D6200 RS10840
gene id: 104268:D6200_RS10840
uniprot id: A0A1M5DPN6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

104268:D6200 RS01750
gene id: 104268:D6200_RS01750
uniprot id: A0A1M5G167
names: Cofactor
messages: Can also use Mn(2+) ion.

104268:D6200 RS02420
gene id: 104268:D6200_RS02420
uniprot id: A0A1M5FTY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

104268:D6200 RS00115
gene id: 104268:D6200_RS00115
uniprot id: A0A1M5CCN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

104268:D6200 RS11835
gene id: 104268:D6200_RS11835
uniprot id: A0A1M5DDI5
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

104268:D6200 RS12740
gene id: 104268:D6200_RS12740
uniprot id: A0A1M5D5F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

104268:D6200 RS11290
gene id: 104268:D6200_RS11290
uniprot id: A0A1M5DJB6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS03015
gene id: 104268:D6200_RS03015
uniprot id: A0A1M5GAC4
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS07245
gene id: 104268:D6200_RS07245
uniprot id: A0A1M5HAN0
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS15115
gene id: 104268:D6200_RS15115
uniprot id: A0A1M5CDU0
names: Similarity
messages: Belongs to the SusD family.

104268:D6200 RS09195
gene id: 104268:D6200_RS09195
uniprot id: A0A1M5E8Y8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

104268:D6200 RS03960
gene id: 104268:D6200_RS03960
uniprot id: A0A1M5GKP3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

104268:D6200 RS06385
gene id: 104268:D6200_RS06385
uniprot id: A0A1M5HNA7
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

104268:D6200 RS11615
gene id: 104268:D6200_RS11615
uniprot id: A0A1M5DG63
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

104268:D6200 RS10415
gene id: 104268:D6200_RS10415
uniprot id: A0A1M5DUM9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

104268:D6200 RS01650
gene id: 104268:D6200_RS01650
uniprot id: A0A1M5G2A0
names: Similarity
messages: Belongs to the RutC family.

104268:D6200 RS04205
gene id: 104268:D6200_RS04205
uniprot id: A0A1M5EXV6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

104268:D6200 RS12625
gene id: 104268:D6200_RS12625
uniprot id: A0A1M5D698
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

104268:D6200 RS05970
gene id: 104268:D6200_RS05970
uniprot id: A0A1M5FH19
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS04505
gene id: 104268:D6200_RS04505
uniprot id: A0A1M5F152
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

104268:D6200 RS05225
gene id: 104268:D6200_RS05225
uniprot id: A0A1M5F9K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

104268:D6200 RS00060
gene id: 104268:D6200_RS00060
uniprot id: A0A1M5CD76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

104268:D6200 RS00140
gene id: 104268:D6200_RS00140
uniprot id: A0A1M5CCH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

104268:D6200 RS12110
gene id: 104268:D6200_RS12110
uniprot id: A0A1M5DB63
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS06810
gene id: 104268:D6200_RS06810
uniprot id: A0A1M5H537
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS13900
gene id: 104268:D6200_RS13900
uniprot id: A0A1M5CRM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

104268:D6200 RS03780
gene id: 104268:D6200_RS03780
uniprot id: A0A1M5GIM2
names: Similarity
messages: Belongs to the Skp family.

104268:D6200 RS02995
gene id: 104268:D6200_RS02995
uniprot id: A0A1M5GA22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS05165
gene id: 104268:D6200_RS05165
uniprot id: A0A1M5FA71
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

104268:D6200 RS08215
gene id: 104268:D6200_RS08215
uniprot id: A0A1M5GY58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS06210
gene id: 104268:D6200_RS06210
uniprot id: A0A1M5HQ16
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

104268:D6200 RS15155
gene id: 104268:D6200_RS15155
uniprot id: A0A1M5CDE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

104268:D6200 RS02305
gene id: 104268:D6200_RS02305
uniprot id: A0A1M5FVS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

104268:D6200 RS09850
gene id: 104268:D6200_RS09850
uniprot id: A0A1M5E0P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

104268:D6200 RS08520
gene id: 104268:D6200_RS08520
uniprot id: A0A1M5GUL7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

104268:D6200 RS05995
gene id: 104268:D6200_RS05995
uniprot id: A0A1M5FI90
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

104268:D6200 RS03890
gene id: 104268:D6200_RS03890
uniprot id: A0A1M5GJT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

104268:D6200 RS12765
gene id: 104268:D6200_RS12765
uniprot id: A0A1M5D4D0
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS00245
gene id: 104268:D6200_RS00245
uniprot id: A0A1M5CBJ9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

104268:D6200 RS14515
gene id: 104268:D6200_RS14515
uniprot id: A0A1M5CJE2
names: Similarity
messages: Belongs to the SusD family.

104268:D6200 RS07275
gene id: 104268:D6200_RS07275
uniprot id: A0A1M5HAE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

104268:D6200 RS06135
gene id: 104268:D6200_RS06135
uniprot id: A0A1M5HQV7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

104268:D6200 RS09535
gene id: 104268:D6200_RS09535
uniprot id: A0A1M5E4J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

104268:D6200 RS01805
gene id: 104268:D6200_RS01805
uniprot id: A0A1M5G0Q1
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

104268:D6200 RS06115
gene id: 104268:D6200_RS06115
uniprot id: A0A1M5HR16
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

104268:D6200 RS04100
gene id: 104268:D6200_RS04100
uniprot id: A0A1M5EXJ4
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

104268:D6200 RS01835
gene id: 104268:D6200_RS01835
uniprot id: A0A1M5FZK9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

104268:D6200 RS00790
gene id: 104268:D6200_RS00790
uniprot id: A0A1M5C6W9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

104268:D6200 RS01015
gene id: 104268:D6200_RS01015
uniprot id: A0A1M5C4T3
names: Subcellular Location Annotation
messages: Cytoplasm

104268:D6200 RS00065
gene id: 104268:D6200_RS00065
uniprot id: A0A1M5CCZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

104268:D6200 RS11215
gene id: 104268:D6200_RS11215
uniprot id: A0A1M5DKE6
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS04020
gene id: 104268:D6200_RS04020
uniprot id: A0A1M5GLD9
names: Similarity
messages: Belongs to the SCO1/2 family.

104268:D6200 RS11890
gene id: 104268:D6200_RS11890
uniprot id: A0A1M5DDA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

104268:D6200 RS03030
gene id: 104268:D6200_RS03030
uniprot id: A0A1M5GAM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

104268:D6200 RS14540
gene id: 104268:D6200_RS14540
uniprot id: A0A1M5CJ12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

104268:D6200 RS13605
gene id: 104268:D6200_RS13605
uniprot id: A0A1M5CUR2
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

104268:D6200 RS03745
gene id: 104268:D6200_RS03745
uniprot id: A0A1M5GI82
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS14460
gene id: 104268:D6200_RS14460
uniprot id: A0A1M5CK75
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS05950
gene id: 104268:D6200_RS05950
uniprot id: A0A1M5FGU9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

104268:D6200 RS02220
gene id: 104268:D6200_RS02220
uniprot id: A0A1M5FWP1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

104268:D6200 RS03125
gene id: 104268:D6200_RS03125
uniprot id: A0A1M5GBJ4
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS09110
gene id: 104268:D6200_RS09110
uniprot id: A0A1M5E9W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

104268:D6200 RS00795
gene id: 104268:D6200_RS00795
uniprot id: A0A1M5C6G2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

104268:D6200 RS08860
gene id: 104268:D6200_RS08860
uniprot id: A0A1M5ECU0
names: Similarity
messages: Belongs to the peptidase M16 family.

104268:D6200 RS04965
gene id: 104268:D6200_RS04965
uniprot id: A0A1M5F6N7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

104268:D6200 RS11340
gene id: 104268:D6200_RS11340
uniprot id: A0A1M5DIY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

104268:D6200 RS05100
gene id: 104268:D6200_RS05100
uniprot id: A0A1M5F9L1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

104268:D6200 RS07225
gene id: 104268:D6200_RS07225
uniprot id: A0A1M5H9Q1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

104268:D6200 RS02715
gene id: 104268:D6200_RS02715
uniprot id: A0A1M5FQW1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS02760
gene id: 104268:D6200_RS02760
uniprot id: A0A1M5FQT5
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

104268:D6200 RS09150
gene id: 104268:D6200_RS09150
uniprot id: A0A1M5E9J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

104268:D6200 RS11900
gene id: 104268:D6200_RS11900
uniprot id: A0A1M5DDA2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

104268:D6200 RS05955
gene id: 104268:D6200_RS05955
uniprot id: A0A1M5FGX0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

104268:D6200 RS05425
gene id: 104268:D6200_RS05425
uniprot id: A0A1M5FCS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

104268:D6200 RS00325
gene id: 104268:D6200_RS00325
uniprot id: A0A1M5CBP1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

104268:D6200 RS01615
gene id: 104268:D6200_RS01615
uniprot id: A0A1M5G2R3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

104268:D6200 RS01425
gene id: 104268:D6200_RS01425
uniprot id: A0A1M5C1D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

104268:D6200 RS05960
gene id: 104268:D6200_RS05960
uniprot id: A0A1M5FGS1
names: Similarity
messages: Belongs to the CinA family.

104268:D6200 RS07615
gene id: 104268:D6200_RS07615
uniprot id: A0A1M5HGS4
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS07745
gene id: 104268:D6200_RS07745
uniprot id: A0A1M5HI16
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

104268:D6200 RS12505
gene id: 104268:D6200_RS12505
uniprot id: A0A1M5D7F8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

104268:D6200 RS00935
gene id: 104268:D6200_RS00935
uniprot id: A0A1M5C572
names: Similarity
messages: Belongs to the NusB family.

104268:D6200 RS12325
gene id: 104268:D6200_RS12325
uniprot id: A0A1M5D9G0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

104268:D6200 RS08680
gene id: 104268:D6200_RS08680
uniprot id: A0A1M5GSR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

104268:D6200 RS05285
gene id: 104268:D6200_RS05285
uniprot id: A0A1M5FAE8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

104268:D6200 RS13625
gene id: 104268:D6200_RS13625
uniprot id: A0A1M5CUM4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

104268:D6200 RS00075
gene id: 104268:D6200_RS00075
uniprot id: A0A1M5CCW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

104268:D6200 RS00450
gene id: 104268:D6200_RS00450
uniprot id: A0A1M5C9Y4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS03025
gene id: 104268:D6200_RS03025
uniprot id: A0A1M5GAE1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

104268:D6200 RS10180
gene id: 104268:D6200_RS10180
uniprot id: A0A1M5DXM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

104268:D6200 RS14525
gene id: 104268:D6200_RS14525
uniprot id: A0A1M5CJQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

104268:D6200 RS00180
gene id: 104268:D6200_RS00180
uniprot id: A0A1M5CC01
names: Similarity
messages: Belongs to the citrate synthase family.

104268:D6200 RS05130
gene id: 104268:D6200_RS05130
uniprot id: A0A1M5F8F8
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

104268:D6200 RS03165
gene id: 104268:D6200_RS03165
uniprot id: A0A1M5GC75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

104268:D6200 RS14595
gene id: 104268:D6200_RS14595
uniprot id: A0A1M5CIN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

104268:D6200 RS12935
gene id: 104268:D6200_RS12935
uniprot id: A0A1M5D2A8
names: Cofactor
messages: Binds 1 FAD per subunit.

104268:D6200 RS10065
gene id: 104268:D6200_RS10065
uniprot id: A0A1M5DYS3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS09680
gene id: 104268:D6200_RS09680
uniprot id: A0A1M5E2Q1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

104268:D6200 RS12640
gene id: 104268:D6200_RS12640
uniprot id: A0A1M5D656
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for cell division and gliding motility.

104268:D6200 RS11950
gene id: 104268:D6200_RS11950
uniprot id: A0A1M5DDE2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

104268:D6200 RS07175
gene id: 104268:D6200_RS07175
uniprot id: A0A1M5H9E2
names: Similarity
messages: Belongs to the LOG family.

104268:D6200 RS00120
gene id: 104268:D6200_RS00120
uniprot id: A0A1M5CCL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

104268:D6200 RS00340
gene id: 104268:D6200_RS00340
uniprot id: A0A1M5CAL8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

104268:D6200 RS07035
gene id: 104268:D6200_RS07035
uniprot id: A0A1M5H8J1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

104268:D6200 RS13205
gene id: 104268:D6200_RS13205
uniprot id: A0A1M5CZ07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

104268:D6200 RS06310
gene id: 104268:D6200_RS06310
uniprot id: A0A1M5HP29
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

104268:D6200 RS02200
gene id: 104268:D6200_RS02200
uniprot id: A0A1M5FW13
names: Similarity
messages: Belongs to the SUI1 family.

104268:D6200 RS09815
gene id: 104268:D6200_RS09815
uniprot id: A0A1M5E1A6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

104268:D6200 RS11665
gene id: 104268:D6200_RS11665
uniprot id: A0A1M5DFS9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

104268:D6200 RS15200
gene id: 104268:D6200_RS15200
uniprot id: A0A1M5CD76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

104268:D6200 RS03615
gene id: 104268:D6200_RS03615
uniprot id: A0A1M5GHE3
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

104268:D6200 RS14420
gene id: 104268:D6200_RS14420
uniprot id: A0A1M5CLF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

104268:D6200 RS11155
gene id: 104268:D6200_RS11155
uniprot id: A0A1M5DKS0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

104268:D6200 RS08595
gene id: 104268:D6200_RS08595
uniprot id: A0A1M5GTU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

104268:D6200 RS09975
gene id: 104268:D6200_RS09975
uniprot id: A0A1M5DZX4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

104268:D6200 RS03680
gene id: 104268:D6200_RS03680
uniprot id: A0A1M5GHJ0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

104268:D6200 RS04335
gene id: 104268:D6200_RS04335
uniprot id: A0A1M5EZK1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

104268:D6200 RS06730
gene id: 104268:D6200_RS06730
uniprot id: A0A1M5H4A2
names: Subcellular Location Annotation
messages: Membrane

104268:D6200 RS08600
gene id: 104268:D6200_RS08600
uniprot id: A0A1M5GTY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

104268:D6200 RS03790
gene id: 104268:D6200_RS03790
uniprot id: A0A1M5GIL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

104268:D6200 RS02415
gene id: 104268:D6200_RS02415
uniprot id: A0A1M5FU06
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

104268:D6200 RS06870
gene id: 104268:D6200_RS06870
uniprot id: A0A1M5H5Y6
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

104268:D6200 RS04415
gene id: 104268:D6200_RS04415
uniprot id: A0A1M5F0G4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

104268:D6200 RS10350
gene id: 104268:D6200_RS10350
uniprot id: A0A1M5DVB9
names: Similarity
messages: Belongs to the transglycosylase Slt family.

104268:D6200 RS07340
gene id: 104268:D6200_RS07340
uniprot id: A0A1M5HB58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

104268:D6200 RS05670
gene id: 104268:D6200_RS05670
uniprot id: A0A1M5FES0
names: Similarity
messages: Belongs to the group II decarboxylase family.

104268:D6200 RS08930
gene id: 104268:D6200_RS08930
uniprot id: A0A1M5ECK4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

104268:D6200 RS12475
gene id: 104268:D6200_RS12475
uniprot id: A0A1M5D7H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

104268:D6200 RS11040
gene id: 104268:D6200_RS11040
uniprot id: A0A1M5DM79
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

104268:D6200 RS07865
gene id: 104268:D6200_RS07865
uniprot id: A0A1M5HJF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

104268:D6200 RS13810
gene id: 104268:D6200_RS13810
uniprot id: A0A1M5CTR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.