1038856:BBI15 RS00935
gene id: 1038856:BBI15_RS00935
uniprot id: A0A1C7EBA2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1038856:BBI15 RS01895
gene id: 1038856:BBI15_RS01895
uniprot id: A0A1C7EBM1
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1038856:BBI15 RS10780
gene id: 1038856:BBI15_RS10780
uniprot id: A0A1C7E7Y9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1038856:BBI15 RS01765
gene id: 1038856:BBI15_RS01765
uniprot id: A0A1C7EAT1
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.

1038856:BBI15 RS09310
gene id: 1038856:BBI15_RS09310
uniprot id: A0A1C7E7A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1038856:BBI15 RS08830
gene id: 1038856:BBI15_RS08830
uniprot id: A0A1C7E6Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1038856:BBI15 RS07295
gene id: 1038856:BBI15_RS07295
uniprot id: A0A1C7E692
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1038856:BBI15 RS06890
gene id: 1038856:BBI15_RS06890
uniprot id: A0A1C7E609
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1038856:BBI15 RS10000
gene id: 1038856:BBI15_RS10000
uniprot id: A0A1C7E757
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1038856:BBI15 RS13395
gene id: 1038856:BBI15_RS13395
uniprot id: A0A1C7EA44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1038856:BBI15 RS11170
gene id: 1038856:BBI15_RS11170
uniprot id: A0A1C7E853
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1038856:BBI15 RS09580
gene id: 1038856:BBI15_RS09580
uniprot id: A0A1C7E7F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1038856:BBI15 RS03105
gene id: 1038856:BBI15_RS03105
uniprot id: A0A1C7EC71
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1038856:BBI15 RS06060
gene id: 1038856:BBI15_RS06060
uniprot id: A0A1C7E6A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS02500
gene id: 1038856:BBI15_RS02500
uniprot id: A0A1C7EBX1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1038856:BBI15 RS02605
gene id: 1038856:BBI15_RS02605
uniprot id: A0A1C7EBY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1038856:BBI15 RS00115
gene id: 1038856:BBI15_RS00115
uniprot id: A0A1C7EAX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1038856:BBI15 RS15095
gene id: 1038856:BBI15_RS15095
uniprot id: A0A1C7E9G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1038856:BBI15 RS14315
gene id: 1038856:BBI15_RS14315
uniprot id: A0A1C7EAM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS06440
gene id: 1038856:BBI15_RS06440
uniprot id: A0A1C7ED75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1038856:BBI15 RS16200
gene id: 1038856:BBI15_RS16200
uniprot id: A0A1C7EAR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1038856:BBI15 RS09455
gene id: 1038856:BBI15_RS09455
uniprot id: A0A1C7E6V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

1038856:BBI15 RS01095
gene id: 1038856:BBI15_RS01095
uniprot id: A0A1C7EB81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1038856:BBI15 RS02800
gene id: 1038856:BBI15_RS02800
uniprot id: A0A1C7EBB4
names: Function
names: Subcellular Location Annotation
messages: Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA).
messages: Cytoplasm

1038856:BBI15 RS08570
gene id: 1038856:BBI15_RS08570
uniprot id: A0A1C7E7L7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1038856:BBI15 RS13565
gene id: 1038856:BBI15_RS13565
uniprot id: A0A1C7EA74
names: Similarity
messages: Belongs to the peptidase S13 family.

1038856:BBI15 RS09180
gene id: 1038856:BBI15_RS09180
uniprot id: A0A1C7E746
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1038856:BBI15 RS02705
gene id: 1038856:BBI15_RS02705
uniprot id: A0A1C7EC54
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS10640
gene id: 1038856:BBI15_RS10640
uniprot id: A0A1C7E8Q8
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS09120
gene id: 1038856:BBI15_RS09120
uniprot id: A0A1C7E737
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1038856:BBI15 RS02205
gene id: 1038856:BBI15_RS02205
uniprot id: A0A1C7ECR2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1038856:BBI15 RS04915
gene id: 1038856:BBI15_RS04915
uniprot id: A0A1C7E532
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1038856:BBI15 RS02165
gene id: 1038856:BBI15_RS02165
uniprot id: A0A1C7ECP0
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS07900
gene id: 1038856:BBI15_RS07900
uniprot id: A0A1C7E775
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1038856:BBI15 RS02085
gene id: 1038856:BBI15_RS02085
uniprot id: A0A1C7EAZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1038856:BBI15 RS13810
gene id: 1038856:BBI15_RS13810
uniprot id: A0A1C7E9J0
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS10785
gene id: 1038856:BBI15_RS10785
uniprot id: A0A1C7E7Y2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1038856:BBI15 RS07025
gene id: 1038856:BBI15_RS07025
uniprot id: A0A1C7E6Q3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1038856:BBI15 RS06085
gene id: 1038856:BBI15_RS06085
uniprot id: A0A1C7E599
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1038856:BBI15 RS00120
gene id: 1038856:BBI15_RS00120
uniprot id: A0A1C7EAV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1038856:BBI15 RS00770
gene id: 1038856:BBI15_RS00770
uniprot id: A0A1C7EB82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1038856:BBI15 RS00205
gene id: 1038856:BBI15_RS00205
uniprot id: A0A1C7EAT8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS15985
gene id: 1038856:BBI15_RS15985
uniprot id: A0A1C7E9U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

1038856:BBI15 RS07550
gene id: 1038856:BBI15_RS07550
uniprot id: A0A1C7E694
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1038856:BBI15 RS12680
gene id: 1038856:BBI15_RS12680
uniprot id: A0A1C7E859
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1038856:BBI15 RS04750
gene id: 1038856:BBI15_RS04750
uniprot id: A0A1C7E4N3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1038856:BBI15 RS07195
gene id: 1038856:BBI15_RS07195
uniprot id: A0A1C7E5D9
names: Function
messages: Required for transformation and DNA binding.

1038856:BBI15 RS02465
gene id: 1038856:BBI15_RS02465
uniprot id: A0A1C7ECW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS14035
gene id: 1038856:BBI15_RS14035
uniprot id: A0A1C7E9M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS13585
gene id: 1038856:BBI15_RS13585
uniprot id: A0A1C7E903
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1038856:BBI15 RS04595
gene id: 1038856:BBI15_RS04595
uniprot id: A0A1C7ED51
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1038856:BBI15 RS13490
gene id: 1038856:BBI15_RS13490
uniprot id: A0A1C7E8K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1038856:BBI15 RS10350
gene id: 1038856:BBI15_RS10350
uniprot id: A0A1C7E7U0
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1038856:BBI15 RS06530
gene id: 1038856:BBI15_RS06530
uniprot id: A0A1C7E6F8
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1038856:BBI15 RS06155
gene id: 1038856:BBI15_RS06155
uniprot id: A0A1C7E6A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS00275
gene id: 1038856:BBI15_RS00275
uniprot id: A0A1C7EA25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1038856:BBI15 RS07945
gene id: 1038856:BBI15_RS07945
uniprot id: A0A1C7E6L1
names: Similarity
messages: Belongs to the asp23 family.

1038856:BBI15 RS00475
gene id: 1038856:BBI15_RS00475
uniprot id: A0A1C7EA68
names: Similarity
messages: Belongs to the CtsR family.

1038856:BBI15 RS11860
gene id: 1038856:BBI15_RS11860
uniprot id: A0A1C7E9C5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1038856:BBI15 RS01775
gene id: 1038856:BBI15_RS01775
uniprot id: A0A1C7EAV1
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1038856:BBI15 RS12690
gene id: 1038856:BBI15_RS12690
uniprot id: A0A1C7E925
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1038856:BBI15 RS12890
gene id: 1038856:BBI15_RS12890
uniprot id: A0A1C7E962
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1038856:BBI15 RS14390
gene id: 1038856:BBI15_RS14390
uniprot id: A0A1C7E9V8
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS02850
gene id: 1038856:BBI15_RS02850
uniprot id: A0A1C7EC90
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS14095
gene id: 1038856:BBI15_RS14095
uniprot id: A0A1C7E9S9
names: Subcellular Location Annotation
messages: Cell membrane

1038856:BBI15 RS10510
gene id: 1038856:BBI15_RS10510
uniprot id: A0A1C7E7V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS05940
gene id: 1038856:BBI15_RS05940
uniprot id: A0A1C7E5L6
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS15555
gene id: 1038856:BBI15_RS15555
uniprot id: A0A1C7E9L3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1038856:BBI15 RS16090
gene id: 1038856:BBI15_RS16090
uniprot id: A0A1C7EBJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1038856:BBI15 RS07580
gene id: 1038856:BBI15_RS07580
uniprot id: A0A1C7E711
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1038856:BBI15 RS11820
gene id: 1038856:BBI15_RS11820
uniprot id: A0A1C7E7R6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS08340
gene id: 1038856:BBI15_RS08340
uniprot id: A0A1C7E7H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS05155
gene id: 1038856:BBI15_RS05155
uniprot id: A0A1C7E4F0
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1038856:BBI15 RS01300
gene id: 1038856:BBI15_RS01300
uniprot id: A0A1C7EBB8
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. MtnX family.
messages: Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).

1038856:BBI15 RS15725
gene id: 1038856:BBI15_RS15725
uniprot id: A0A1C7E9T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1038856:BBI15 RS02200
gene id: 1038856:BBI15_RS02200
uniprot id: A0A1C7EBW9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS13710
gene id: 1038856:BBI15_RS13710
uniprot id: A0A1C7E8P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family. YeeN subfamily.
messages: Cytoplasm

1038856:BBI15 RS13330
gene id: 1038856:BBI15_RS13330
uniprot id: A0A1C7E9E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1038856:BBI15 RS09715
gene id: 1038856:BBI15_RS09715
uniprot id: A0A1C7E7F2
names: Similarity
messages: Belongs to the ribF family.

1038856:BBI15 RS12835
gene id: 1038856:BBI15_RS12835
uniprot id: A0A1C7E8B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1038856:BBI15 RS05430
gene id: 1038856:BBI15_RS05430
uniprot id: A0A1C7E4J6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1038856:BBI15 RS08755
gene id: 1038856:BBI15_RS08755
uniprot id: A0A1C7E702
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1038856:BBI15 RS02410
gene id: 1038856:BBI15_RS02410
uniprot id: A0A1C7ECV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS11165
gene id: 1038856:BBI15_RS11165
uniprot id: A0A1C7E865
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1038856:BBI15 RS07040
gene id: 1038856:BBI15_RS07040
uniprot id: A0A1C7E641
names: Similarity
messages: Belongs to the thioredoxin family.

1038856:BBI15 RS10405
gene id: 1038856:BBI15_RS10405
uniprot id: A0A1C7E7S9
names: Similarity
messages: Belongs to the UPF0637 family.

1038856:BBI15 RS07410
gene id: 1038856:BBI15_RS07410
uniprot id: A0A1C7E6Y2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1038856:BBI15 RS10765
gene id: 1038856:BBI15_RS10765
uniprot id: A0A1C7E815
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
messages: Homodimer.
messages: The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

1038856:BBI15 RS03770
gene id: 1038856:BBI15_RS03770
uniprot id: A0A1C7ECI3
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1038856:BBI15 RS04950
gene id: 1038856:BBI15_RS04950
uniprot id: A0A1C7E567
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1038856:BBI15 RS13680
gene id: 1038856:BBI15_RS13680
uniprot id: A0A1C7E9G0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1038856:BBI15 RS00690
gene id: 1038856:BBI15_RS00690
uniprot id: A0A1C7EB56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1038856:BBI15 RS04965
gene id: 1038856:BBI15_RS04965
uniprot id: A0A1C7E542
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1038856:BBI15 RS09950
gene id: 1038856:BBI15_RS09950
uniprot id: A0A1C7E745
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1038856:BBI15 RS07665
gene id: 1038856:BBI15_RS07665
uniprot id: A0A1C7E6B0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1038856:BBI15 RS09890
gene id: 1038856:BBI15_RS09890
uniprot id: A0A1C7E7F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1038856:BBI15 RS10330
gene id: 1038856:BBI15_RS10330
uniprot id: A0A1C7E7U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1038856:BBI15 RS15185
gene id: 1038856:BBI15_RS15185
uniprot id: A0A1C7E9S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1038856:BBI15 RS04895
gene id: 1038856:BBI15_RS04895
uniprot id: A0A1C7E557
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1038856:BBI15 RS11060
gene id: 1038856:BBI15_RS11060
uniprot id: A0A1C7E846
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1038856:BBI15 RS13970
gene id: 1038856:BBI15_RS13970
uniprot id: A0A1C7EAF3
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS12840
gene id: 1038856:BBI15_RS12840
uniprot id: A0A1C7E952
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1038856:BBI15 RS07770
gene id: 1038856:BBI15_RS07770
uniprot id: A0A1C7E6C8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1038856:BBI15 RS06995
gene id: 1038856:BBI15_RS06995
uniprot id: A0A1C7E5Z1
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS07855
gene id: 1038856:BBI15_RS07855
uniprot id: A0A1C7E6J3
names: Similarity
messages: Belongs to the GSP E family.

1038856:BBI15 RS09615
gene id: 1038856:BBI15_RS09615
uniprot id: A0A1C7E6Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1038856:BBI15 RS01180
gene id: 1038856:BBI15_RS01180
uniprot id: A0A1C7EBD8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1038856:BBI15 RS09805
gene id: 1038856:BBI15_RS09805
uniprot id: A0A1C7E6R0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1038856:BBI15 RS04025
gene id: 1038856:BBI15_RS04025
uniprot id: A0A1C7EDP2
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS05750
gene id: 1038856:BBI15_RS05750
uniprot id: A0A1C7E4M8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1038856:BBI15 RS01240
gene id: 1038856:BBI15_RS01240
uniprot id: A0A1C7EBD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1038856:BBI15 RS12880
gene id: 1038856:BBI15_RS12880
uniprot id: A0A1C7E898
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1038856:BBI15 RS00820
gene id: 1038856:BBI15_RS00820
uniprot id: A0A1C7EB92
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1038856:BBI15 RS06825
gene id: 1038856:BBI15_RS06825
uniprot id: A0A1C7E6L4
names: Similarity
messages: Belongs to the citrate synthase family.

1038856:BBI15 RS03030
gene id: 1038856:BBI15_RS03030
uniprot id: A0A1C7EC95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1038856:BBI15 RS09515
gene id: 1038856:BBI15_RS09515
uniprot id: A0A1C7E838
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS07155
gene id: 1038856:BBI15_RS07155
uniprot id: A0A1C7E625
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

1038856:BBI15 RS04665
gene id: 1038856:BBI15_RS04665
uniprot id: A0A1C7E4S9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1038856:BBI15 RS07990
gene id: 1038856:BBI15_RS07990
uniprot id: A0A1C7E6H5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1038856:BBI15 RS05845
gene id: 1038856:BBI15_RS05845
uniprot id: A0A1C7E5E0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1038856:BBI15 RS03690
gene id: 1038856:BBI15_RS03690
uniprot id: A0A1C7ECM4
names: Subcellular Location Annotation
messages: Cell membrane

1038856:BBI15 RS12790
gene id: 1038856:BBI15_RS12790
uniprot id: A0A1C7E943
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1038856:BBI15 RS00760
gene id: 1038856:BBI15_RS00760
uniprot id: A0A1C7EB31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1038856:BBI15 RS05170
gene id: 1038856:BBI15_RS05170
uniprot id: A0A1C7E519
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS04875
gene id: 1038856:BBI15_RS04875
uniprot id: A0A1C7E544
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1038856:BBI15 RS14965
gene id: 1038856:BBI15_RS14965
uniprot id: A0A1C7EA96
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1038856:BBI15 RS10020
gene id: 1038856:BBI15_RS10020
uniprot id: A0A1C7E6U5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS00510
gene id: 1038856:BBI15_RS00510
uniprot id: A0A1C7EB29
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS10070
gene id: 1038856:BBI15_RS10070
uniprot id: A0A1C7E6S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1038856:BBI15 RS04600
gene id: 1038856:BBI15_RS04600
uniprot id: A0A1C7E459
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS12610
gene id: 1038856:BBI15_RS12610
uniprot id: A0A1C7E9R6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1038856:BBI15 RS03090
gene id: 1038856:BBI15_RS03090
uniprot id: A0A1C7ECD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1038856:BBI15 RS00605
gene id: 1038856:BBI15_RS00605
uniprot id: A0A1C7EAZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1038856:BBI15 RS15665
gene id: 1038856:BBI15_RS15665
uniprot id: A0A1C7E9N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1038856:BBI15 RS14335
gene id: 1038856:BBI15_RS14335
uniprot id: A0A1C7E9V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1038856:BBI15 RS00125
gene id: 1038856:BBI15_RS00125
uniprot id: A0A1C7EBN5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1038856:BBI15 RS08725
gene id: 1038856:BBI15_RS08725
uniprot id: A0A1C7E6X0
names: Similarity
messages: Belongs to the citrate synthase family.

1038856:BBI15 RS07905
gene id: 1038856:BBI15_RS07905
uniprot id: A0A1C7E5Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1038856:BBI15 RS04765
gene id: 1038856:BBI15_RS04765
uniprot id: A0A1C7E484
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1038856:BBI15 RS07320
gene id: 1038856:BBI15_RS07320
uniprot id: A0A1C7E654
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1038856:BBI15 RS15775
gene id: 1038856:BBI15_RS15775
uniprot id: A0A1C7E9T2
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1038856:BBI15 RS11635
gene id: 1038856:BBI15_RS11635
uniprot id: A0A1C7E804
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1038856:BBI15 RS13665
gene id: 1038856:BBI15_RS13665
uniprot id: A0A1C7E9K2
names: Similarity
messages: Belongs to the ComB family.

1038856:BBI15 RS14360
gene id: 1038856:BBI15_RS14360
uniprot id: A0A1C7E9E2
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS05695
gene id: 1038856:BBI15_RS05695
uniprot id: A0A1C7E623
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1038856:BBI15 RS02665
gene id: 1038856:BBI15_RS02665
uniprot id: A0A1C7EC06
names: Similarity
messages: Belongs to the CvfB family.

1038856:BBI15 RS10190
gene id: 1038856:BBI15_RS10190
uniprot id: A0A1C7E7Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS14285
gene id: 1038856:BBI15_RS14285
uniprot id: A0A1C7EEA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS00380
gene id: 1038856:BBI15_RS00380
uniprot id: A0A1C7EBT8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1038856:BBI15 RS00150
gene id: 1038856:BBI15_RS00150
uniprot id: A0A1C7EAS3
names: Similarity
messages: Belongs to the GppA/Ppx family.

1038856:BBI15 RS12485
gene id: 1038856:BBI15_RS12485
uniprot id: A0A1C7E8U1
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS07005
gene id: 1038856:BBI15_RS07005
uniprot id: A0A1C7E613
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1038856:BBI15 RS13715
gene id: 1038856:BBI15_RS13715
uniprot id: A0A1C7E8T4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
messages: Catalyzes the production of nitric oxide.
messages: Homodimer.
messages: This protein is similar to the oxygenase domain of eukaryotic nitric oxide synthases but lacks the reductase domain which, in eukaryotes, is responsible for transfer of electrons to the ferric heme during nitric oxide synthesis.

1038856:BBI15 RS07130
gene id: 1038856:BBI15_RS07130
uniprot id: A0A1C7E661
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1038856:BBI15 RS02030
gene id: 1038856:BBI15_RS02030
uniprot id: A0A1C7EAY2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS06390
gene id: 1038856:BBI15_RS06390
uniprot id: A0A1C7E4W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

1038856:BBI15 RS02710
gene id: 1038856:BBI15_RS02710
uniprot id: A0A1C7EC63
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1038856:BBI15 RS14940
gene id: 1038856:BBI15_RS14940
uniprot id: A0A1C7EAY1
names: Similarity
messages: Belongs to the PrpF family.

1038856:BBI15 RS05115
gene id: 1038856:BBI15_RS05115
uniprot id: A0A1C7E598
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1038856:BBI15 RS10700
gene id: 1038856:BBI15_RS10700
uniprot id: A0A1C7E8R7
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. YjcG family.

1038856:BBI15 RS10520
gene id: 1038856:BBI15_RS10520
uniprot id: A0A1C7E7T5
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1038856:BBI15 RS09005
gene id: 1038856:BBI15_RS09005
uniprot id: A0A1C7E7S4
names: Similarity
messages: Belongs to the peptidase S66 family.

1038856:BBI15 RS10840
gene id: 1038856:BBI15_RS10840
uniprot id: A0A1C7E7Z8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1038856:BBI15 RS15895
gene id: 1038856:BBI15_RS15895
uniprot id: A0A1C7EAQ0
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS00145
gene id: 1038856:BBI15_RS00145
uniprot id: A0A1C7EAT2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1038856:BBI15 RS05920
gene id: 1038856:BBI15_RS05920
uniprot id: A0A1C7E5K9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1038856:BBI15 RS12925
gene id: 1038856:BBI15_RS12925
uniprot id: A0A1C7E960
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1038856:BBI15 RS04910
gene id: 1038856:BBI15_RS04910
uniprot id: A0A1C7E5Q5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.

1038856:BBI15 RS10320
gene id: 1038856:BBI15_RS10320
uniprot id: A0A1C7E7P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Membrane

1038856:BBI15 RS00700
gene id: 1038856:BBI15_RS00700
uniprot id: A0A1C7EBX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1038856:BBI15 RS12110
gene id: 1038856:BBI15_RS12110
uniprot id: A0A1C7E9H6
names: Similarity
messages: Belongs to the CpsD/CapB family.

1038856:BBI15 RS02480
gene id: 1038856:BBI15_RS02480
uniprot id: A0A1C7EC19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

1038856:BBI15 RS08280
gene id: 1038856:BBI15_RS08280
uniprot id: A0A1C7E6B7
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1038856:BBI15 RS09920
gene id: 1038856:BBI15_RS09920
uniprot id: A0A1C7E6S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1038856:BBI15 RS09820
gene id: 1038856:BBI15_RS09820
uniprot id: A0A1C7E877
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1038856:BBI15 RS12695
gene id: 1038856:BBI15_RS12695
uniprot id: A0A1C7E8Z4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS04795
gene id: 1038856:BBI15_RS04795
uniprot id: A0A1C7E4X3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1038856:BBI15 RS08880
gene id: 1038856:BBI15_RS08880
uniprot id: A0A1C7E729
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS00575
gene id: 1038856:BBI15_RS00575
uniprot id: A0A1C7EA69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1038856:BBI15 RS09830
gene id: 1038856:BBI15_RS09830
uniprot id: A0A1C7E7F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1038856:BBI15 RS04525
gene id: 1038856:BBI15_RS04525
uniprot id: A0A1C7ECY2
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1038856:BBI15 RS07940
gene id: 1038856:BBI15_RS07940
uniprot id: A0A1C7E652
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1038856:BBI15 RS05415
gene id: 1038856:BBI15_RS05415
uniprot id: A0A1C7E5C1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1038856:BBI15 RS08480
gene id: 1038856:BBI15_RS08480
uniprot id: A0A1C7E7H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1038856:BBI15 RS09700
gene id: 1038856:BBI15_RS09700
uniprot id: A0A1C7E6K9
names: Similarity
messages: Belongs to the peptidase M16 family.

1038856:BBI15 RS15595
gene id: 1038856:BBI15_RS15595
uniprot id: A0A1C7EAK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1038856:BBI15 RS01120
gene id: 1038856:BBI15_RS01120
uniprot id: A0A1C7EAI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1038856:BBI15 RS09165
gene id: 1038856:BBI15_RS09165
uniprot id: A0A1C7E758
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS06920
gene id: 1038856:BBI15_RS06920
uniprot id: A0A1C7E617
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1038856:BBI15 RS06805
gene id: 1038856:BBI15_RS06805
uniprot id: A0A1C7E5X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1038856:BBI15 RS08355
gene id: 1038856:BBI15_RS08355
uniprot id: A0A1C7E5Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS09345
gene id: 1038856:BBI15_RS09345
uniprot id: A0A1C7E774
names: Similarity
messages: Belongs to the asparaginase 1 family.

1038856:BBI15 RS09555
gene id: 1038856:BBI15_RS09555
uniprot id: A0A1C7E6X7
names: Similarity
messages: Belongs to the glutamine synthetase family.

1038856:BBI15 RS13080
gene id: 1038856:BBI15_RS13080
uniprot id: A0A1C7E8R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS00980
gene id: 1038856:BBI15_RS00980
uniprot id: A0A1C7EC10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1038856:BBI15 RS16045
gene id: 1038856:BBI15_RS16045
uniprot id: A0A1C7E9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS12155
gene id: 1038856:BBI15_RS12155
uniprot id: A0A1C7E8S5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1038856:BBI15 RS04855
gene id: 1038856:BBI15_RS04855
uniprot id: A0A1C7E5P9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1038856:BBI15 RS13795
gene id: 1038856:BBI15_RS13795
uniprot id: A0A1C7EAC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS06760
gene id: 1038856:BBI15_RS06760
uniprot id: A0A1C7E5U5
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1038856:BBI15 RS02220
gene id: 1038856:BBI15_RS02220
uniprot id: A0A1C7EBX4
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS13985
gene id: 1038856:BBI15_RS13985
uniprot id: A0A1C7E978
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1038856:BBI15 RS03035
gene id: 1038856:BBI15_RS03035
uniprot id: A0A1C7ECB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1038856:BBI15 RS14520
gene id: 1038856:BBI15_RS14520
uniprot id: A0A1C7E9V3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1038856:BBI15 RS06015
gene id: 1038856:BBI15_RS06015
uniprot id: A0A1C7E5G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1038856:BBI15 RS06505
gene id: 1038856:BBI15_RS06505
uniprot id: A0A1C7E4Z3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1038856:BBI15 RS06030
gene id: 1038856:BBI15_RS06030
uniprot id: A0A1C7E687
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1038856:BBI15 RS15400
gene id: 1038856:BBI15_RS15400
uniprot id: A0A1C7EAC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1038856:BBI15 RS14070
gene id: 1038856:BBI15_RS14070
uniprot id: A0A1C7E9Q0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1038856:BBI15 RS03905
gene id: 1038856:BBI15_RS03905
uniprot id: A0A1C7ECT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1038856:BBI15 RS04845
gene id: 1038856:BBI15_RS04845
uniprot id: A0A1C7E547
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1038856:BBI15 RS00985
gene id: 1038856:BBI15_RS00985
uniprot id: A0A1C7EB57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1038856:BBI15 RS04675
gene id: 1038856:BBI15_RS04675
uniprot id: A0A1C7E4Z0
names: Similarity
messages: Belongs to the transpeptidase family.

1038856:BBI15 RS00280
gene id: 1038856:BBI15_RS00280
uniprot id: A0A1C7EA48
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS04410
gene id: 1038856:BBI15_RS04410
uniprot id: A0A1C7EDW2
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS06150
gene id: 1038856:BBI15_RS06150
uniprot id: A0A1C7E5R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS08885
gene id: 1038856:BBI15_RS08885
uniprot id: A0A1C7E700
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1038856:BBI15 RS09465
gene id: 1038856:BBI15_RS09465
uniprot id: A0A1C7E828
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1038856:BBI15 RS16175
gene id: 1038856:BBI15_RS16175
uniprot id: A0A1C7E9Z7
names: Similarity
messages: Belongs to the ParB family.

1038856:BBI15 RS10150
gene id: 1038856:BBI15_RS10150
uniprot id: A0A1C7E8D5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1038856:BBI15 RS08780
gene id: 1038856:BBI15_RS08780
uniprot id: A0A1C7E6Y0
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS05050
gene id: 1038856:BBI15_RS05050
uniprot id: A0A1C7E4D0
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1038856:BBI15 RS02900
gene id: 1038856:BBI15_RS02900
uniprot id: A0A1C7EC99
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).

1038856:BBI15 RS12115
gene id: 1038856:BBI15_RS12115
uniprot id: A0A1C7E7V9
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS09815
gene id: 1038856:BBI15_RS09815
uniprot id: A0A1C7E7H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1038856:BBI15 RS09690
gene id: 1038856:BBI15_RS09690
uniprot id: A0A1C7E869
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1038856:BBI15 RS13505
gene id: 1038856:BBI15_RS13505
uniprot id: A0A1C7E9E7
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1038856:BBI15 RS09800
gene id: 1038856:BBI15_RS09800
uniprot id: A0A1C7E6M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1038856:BBI15 RS03000
gene id: 1038856:BBI15_RS03000
uniprot id: A0A1C7EC48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1038856:BBI15 RS02855
gene id: 1038856:BBI15_RS02855
uniprot id: A0A1C7ED50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1038856:BBI15 RS03835
gene id: 1038856:BBI15_RS03835
uniprot id: A0A1C7EDN6
names: Function
names: Similarity
messages: Belongs to the peptidase S33 family.
messages: Releases the N-terminal proline from various substrates.

1038856:BBI15 RS04930
gene id: 1038856:BBI15_RS04930
uniprot id: A0A1C7E554
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1038856:BBI15 RS13255
gene id: 1038856:BBI15_RS13255
uniprot id: A0A1C7E9D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1038856:BBI15 RS03150
gene id: 1038856:BBI15_RS03150
uniprot id: A0A1C7ECB4
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1038856:BBI15 RS14130
gene id: 1038856:BBI15_RS14130
uniprot id: A0A1C7EDE4
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1038856:BBI15 RS09840
gene id: 1038856:BBI15_RS09840
uniprot id: A0A1C7E7J5
names: Similarity
messages: Belongs to the DprA/Smf family.

1038856:BBI15 RS00305
gene id: 1038856:BBI15_RS00305
uniprot id: A0A1C7EAV7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1038856:BBI15 RS12860
gene id: 1038856:BBI15_RS12860
uniprot id: A0A1C7E916
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

1038856:BBI15 RS13520
gene id: 1038856:BBI15_RS13520
uniprot id: A0A1C7E9D5
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS01360
gene id: 1038856:BBI15_RS01360
uniprot id: A0A1C7EAX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1038856:BBI15 RS12030
gene id: 1038856:BBI15_RS12030
uniprot id: A0A1C7E8L9
names: Subcellular Location Annotation
messages: Cell membrane

1038856:BBI15 RS13620
gene id: 1038856:BBI15_RS13620
uniprot id: A0A1C7EA84
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1038856:BBI15 RS11985
gene id: 1038856:BBI15_RS11985
uniprot id: A0A1C7E9C1
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS12105
gene id: 1038856:BBI15_RS12105
uniprot id: A0A1C7E8R5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1038856:BBI15 RS01760
gene id: 1038856:BBI15_RS01760
uniprot id: A0A1C7ECI0
names: Similarity
messages: Belongs to the SCO1/2 family.

1038856:BBI15 RS02310
gene id: 1038856:BBI15_RS02310
uniprot id: A0A1C7ECT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1038856:BBI15 RS02995
gene id: 1038856:BBI15_RS02995
uniprot id: A0A1C7EC57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1038856:BBI15 RS01075
gene id: 1038856:BBI15_RS01075
uniprot id: A0A1C7EBB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1038856:BBI15 RS00270
gene id: 1038856:BBI15_RS00270
uniprot id: A0A1C7EBS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1038856:BBI15 RS07705
gene id: 1038856:BBI15_RS07705
uniprot id: A0A1C7E6C4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1038856:BBI15 RS06875
gene id: 1038856:BBI15_RS06875
uniprot id: A0A1C7E6M5
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

1038856:BBI15 RS07345
gene id: 1038856:BBI15_RS07345
uniprot id: A0A1C7E697
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1038856:BBI15 RS08290
gene id: 1038856:BBI15_RS08290
uniprot id: A0A1C7E7G4
names: Similarity
messages: Belongs to the FGGY kinase family.

1038856:BBI15 RS08270
gene id: 1038856:BBI15_RS08270
uniprot id: A0A1C7E6P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS09895
gene id: 1038856:BBI15_RS09895
uniprot id: A0A1C7E738
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1038856:BBI15 RS05070
gene id: 1038856:BBI15_RS05070
uniprot id: A0A1C7E5U0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1038856:BBI15 RS02335
gene id: 1038856:BBI15_RS02335
uniprot id: A0A1C7ECR7
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS10265
gene id: 1038856:BBI15_RS10265
uniprot id: A0A1C7E7P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1038856:BBI15 RS09795
gene id: 1038856:BBI15_RS09795
uniprot id: A0A1C7E889
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS08515
gene id: 1038856:BBI15_RS08515
uniprot id: A0A1C7E7L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

1038856:BBI15 RS00565
gene id: 1038856:BBI15_RS00565
uniprot id: A0A1C7EB39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1038856:BBI15 RS06790
gene id: 1038856:BBI15_RS06790
uniprot id: A0A1C7E5Z0
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.

1038856:BBI15 RS13015
gene id: 1038856:BBI15_RS13015
uniprot id: A0A1C7E935
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1038856:BBI15 RS00795
gene id: 1038856:BBI15_RS00795
uniprot id: A0A1C7EB71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS12495
gene id: 1038856:BBI15_RS12495
uniprot id: A0A1C7E8Y7
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS04060
gene id: 1038856:BBI15_RS04060
uniprot id: A0A1C7EDT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1038856:BBI15 RS00745
gene id: 1038856:BBI15_RS00745
uniprot id: A0A1C7EB60
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1038856:BBI15 RS09295
gene id: 1038856:BBI15_RS09295
uniprot id: A0A1C7E764
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1038856:BBI15 RS07595
gene id: 1038856:BBI15_RS07595
uniprot id: A0A1C7E6D9
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1038856:BBI15 RS09600
gene id: 1038856:BBI15_RS09600
uniprot id: A0A1C7E7C0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1038856:BBI15 RS02000
gene id: 1038856:BBI15_RS02000
uniprot id: A0A1C7ECL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1038856:BBI15 RS06375
gene id: 1038856:BBI15_RS06375
uniprot id: A0A1C7E5C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1038856:BBI15 RS15320
gene id: 1038856:BBI15_RS15320
uniprot id: A0A1C7E9L1
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS10110
gene id: 1038856:BBI15_RS10110
uniprot id: A0A1C7EDA8
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

1038856:BBI15 RS11040
gene id: 1038856:BBI15_RS11040
uniprot id: A0A1C7E7D5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1038856:BBI15 RS07965
gene id: 1038856:BBI15_RS07965
uniprot id: A0A1C7E5T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1038856:BBI15 RS10355
gene id: 1038856:BBI15_RS10355
uniprot id: A0A1C7E7R8
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS06610
gene id: 1038856:BBI15_RS06610
uniprot id: A0A1C7E516
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

1038856:BBI15 RS09340
gene id: 1038856:BBI15_RS09340
uniprot id: A0A1C7E7Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Involved in the degradation of specific anti-sigma factors.
messages: Membrane

1038856:BBI15 RS01290
gene id: 1038856:BBI15_RS01290
uniprot id: A0A1C7EBF1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1038856:BBI15 RS09475
gene id: 1038856:BBI15_RS09475
uniprot id: A0A1C7E6K7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1038856:BBI15 RS02625
gene id: 1038856:BBI15_RS02625
uniprot id: A0A1C7EC52
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1038856:BBI15 RS09835
gene id: 1038856:BBI15_RS09835
uniprot id: A0A1C7E728
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1038856:BBI15 RS01650
gene id: 1038856:BBI15_RS01650
uniprot id: A0A1C7EBM4
names: Similarity
messages: Belongs to the peptidase C40 family.

1038856:BBI15 RS11265
gene id: 1038856:BBI15_RS11265
uniprot id: A0A1C7E8A2
names: Subcellular Location Annotation
messages: Cell membrane

1038856:BBI15 RS14190
gene id: 1038856:BBI15_RS14190
uniprot id: A0A1C7E9Q1
names: Similarity
messages: Belongs to the glutamate synthase family.

1038856:BBI15 RS11450
gene id: 1038856:BBI15_RS11450
uniprot id: A0A1C7E8D8
names: Similarity
messages: Belongs to the AHA1 family.

1038856:BBI15 RS12340
gene id: 1038856:BBI15_RS12340
uniprot id: A0A1C7ECK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

1038856:BBI15 RS06400
gene id: 1038856:BBI15_RS06400
uniprot id: A0A1C7E5S3
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

1038856:BBI15 RS07780
gene id: 1038856:BBI15_RS07780
uniprot id: A0A1C7E620
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS01540
gene id: 1038856:BBI15_RS01540
uniprot id: A0A1C7EAR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS10165
gene id: 1038856:BBI15_RS10165
uniprot id: A0A1C7E787
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1038856:BBI15 RS13430
gene id: 1038856:BBI15_RS13430
uniprot id: A0A1C7E8J7
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS00970
gene id: 1038856:BBI15_RS00970
uniprot id: A0A1C7EB98
names: Subcellular Location Annotation
messages: Cell membrane

1038856:BBI15 RS00160
gene id: 1038856:BBI15_RS00160
uniprot id: A0A1C7EAD1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1038856:BBI15 RS11460
gene id: 1038856:BBI15_RS11460
uniprot id: A0A1C7E8B1
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS15150
gene id: 1038856:BBI15_RS15150
uniprot id: A0A1C7E9I0
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS13090
gene id: 1038856:BBI15_RS13090
uniprot id: A0A1C7EA03
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS07590
gene id: 1038856:BBI15_RS07590
uniprot id: A0A1C7E5L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1038856:BBI15 RS07255
gene id: 1038856:BBI15_RS07255
uniprot id: A0A1C7E5F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

1038856:BBI15 RS05385
gene id: 1038856:BBI15_RS05385
uniprot id: A0A1C7E5C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS00675
gene id: 1038856:BBI15_RS00675
uniprot id: A0A1C7EBY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1038856:BBI15 RS05440
gene id: 1038856:BBI15_RS05440
uniprot id: A0A1C7E548
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1038856:BBI15 RS15995
gene id: 1038856:BBI15_RS15995
uniprot id: A0A1C7EAS0
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS02060
gene id: 1038856:BBI15_RS02060
uniprot id: A0A1C7EBP2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1038856:BBI15 RS05805
gene id: 1038856:BBI15_RS05805
uniprot id: A0A1C7E644
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1038856:BBI15 RS00830
gene id: 1038856:BBI15_RS00830
uniprot id: A0A1C7EAB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1038856:BBI15 RS15415
gene id: 1038856:BBI15_RS15415
uniprot id: A0A1C7E9X7
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1038856:BBI15 RS13185
gene id: 1038856:BBI15_RS13185
uniprot id: A0A1C7E972
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1038856:BBI15 RS14255
gene id: 1038856:BBI15_RS14255
uniprot id: A0A1C7EAM3
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1038856:BBI15 RS03225
gene id: 1038856:BBI15_RS03225
uniprot id: A0A1C7EBW0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1038856:BBI15 RS10205
gene id: 1038856:BBI15_RS10205
uniprot id: A0A1C7E7N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1038856:BBI15 RS02290
gene id: 1038856:BBI15_RS02290
uniprot id: A0A1C7EBU3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS10060
gene id: 1038856:BBI15_RS10060
uniprot id: A0A1C7E7N7
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

1038856:BBI15 RS03245
gene id: 1038856:BBI15_RS03245
uniprot id: A0A1C7EBI0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1038856:BBI15 RS06185
gene id: 1038856:BBI15_RS06185
uniprot id: A0A1C7EE41
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1038856:BBI15 RS14330
gene id: 1038856:BBI15_RS14330
uniprot id: A0A1C7E9Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1038856:BBI15 RS15275
gene id: 1038856:BBI15_RS15275
uniprot id: A0A1C7EAE1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1038856:BBI15 RS15520
gene id: 1038856:BBI15_RS15520
uniprot id: A0A1C7EB86
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS12095
gene id: 1038856:BBI15_RS12095
uniprot id: A0A1C7E8M3
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS00225
gene id: 1038856:BBI15_RS00225
uniprot id: A0A1C7EA16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1038856:BBI15 RS10325
gene id: 1038856:BBI15_RS10325
uniprot id: A0A1C7E7B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS00370
gene id: 1038856:BBI15_RS00370
uniprot id: A0A1C7EAG8
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1038856:BBI15 RS00020
gene id: 1038856:BBI15_RS00020
uniprot id: A0A1C7E9Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1038856:BBI15 RS04710
gene id: 1038856:BBI15_RS04710
uniprot id: A0A1C7E472
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1038856:BBI15 RS15960
gene id: 1038856:BBI15_RS15960
uniprot id: A0A1C7EAM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1038856:BBI15 RS09520
gene id: 1038856:BBI15_RS09520
uniprot id: A0A1C7E6H9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1038856:BBI15 RS15815
gene id: 1038856:BBI15_RS15815
uniprot id: A0A1C7EBF2
names: Similarity
messages: Belongs to the MQO family.

1038856:BBI15 RS12930
gene id: 1038856:BBI15_RS12930
uniprot id: A0A1C7E9X4
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1038856:BBI15 RS10065
gene id: 1038856:BBI15_RS10065
uniprot id: A0A1C7E8E2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS01705
gene id: 1038856:BBI15_RS01705
uniprot id: A0A1C7ECT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1038856:BBI15 RS05130
gene id: 1038856:BBI15_RS05130
uniprot id: A0A1C7E574
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1038856:BBI15 RS14730
gene id: 1038856:BBI15_RS14730
uniprot id: A0A1C7EA10
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1038856:BBI15 RS04125
gene id: 1038856:BBI15_RS04125
uniprot id: A0A1C7ECW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1038856:BBI15 RS12625
gene id: 1038856:BBI15_RS12625
uniprot id: A0A1C7E910
names: Similarity
messages: Belongs to the peptidase S66 family.

1038856:BBI15 RS06585
gene id: 1038856:BBI15_RS06585
uniprot id: A0A1C7E5T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1038856:BBI15 RS10125
gene id: 1038856:BBI15_RS10125
uniprot id: A0A1C7E8F4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1038856:BBI15 RS01235
gene id: 1038856:BBI15_RS01235
uniprot id: A0A1C7EBF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1038856:BBI15 RS00240
gene id: 1038856:BBI15_RS00240
uniprot id: A0A1C7EAX7
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1038856:BBI15 RS13220
gene id: 1038856:BBI15_RS13220
uniprot id: A0A1C7E9C7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

1038856:BBI15 RS12015
gene id: 1038856:BBI15_RS12015
uniprot id: A0A1C7E7T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS14690
gene id: 1038856:BBI15_RS14690
uniprot id: A0A1C7EA49
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1038856:BBI15 RS12830
gene id: 1038856:BBI15_RS12830
uniprot id: A0A1C7E888
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS10155
gene id: 1038856:BBI15_RS10155
uniprot id: A0A1C7E7M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1038856:BBI15 RS05045
gene id: 1038856:BBI15_RS05045
uniprot id: A0A1C7E5S6
names: Similarity
messages: Belongs to the DinB family.

1038856:BBI15 RS04070
gene id: 1038856:BBI15_RS04070
uniprot id: A0A1C7EC22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1038856:BBI15 RS16125
gene id: 1038856:BBI15_RS16125
uniprot id: A0A1C7EAQ3
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1038856:BBI15 RS11365
gene id: 1038856:BBI15_RS11365
uniprot id: A0A1C7E933
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1038856:BBI15 RS12760
gene id: 1038856:BBI15_RS12760
uniprot id: A0A1C7E8Z1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1038856:BBI15 RS02035
gene id: 1038856:BBI15_RS02035
uniprot id: A0A1C7EB03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS05510
gene id: 1038856:BBI15_RS05510
uniprot id: A0A1C7E5Z9
names: Similarity
messages: Belongs to the UPF0342 family.

1038856:BBI15 RS05860
gene id: 1038856:BBI15_RS05860
uniprot id: A0A1C7E657
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1038856:BBI15 RS02810
gene id: 1038856:BBI15_RS02810
uniprot id: A0A1C7EC72
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS01170
gene id: 1038856:BBI15_RS01170
uniprot id: A0A1C7EAH4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1038856:BBI15 RS07825
gene id: 1038856:BBI15_RS07825
uniprot id: A0A1C7E6D8
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1038856:BBI15 RS09255
gene id: 1038856:BBI15_RS09255
uniprot id: A0A1C7E6D5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS04680
gene id: 1038856:BBI15_RS04680
uniprot id: A0A1C7E4V1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1038856:BBI15 RS07890
gene id: 1038856:BBI15_RS07890
uniprot id: A0A1C7E639
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1038856:BBI15 RS05825
gene id: 1038856:BBI15_RS05825
uniprot id: A0A1C7E5J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1038856:BBI15 RS11175
gene id: 1038856:BBI15_RS11175
uniprot id: A0A1C7E7S2
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS00560
gene id: 1038856:BBI15_RS00560
uniprot id: A0A1C7EAJ4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1038856:BBI15 RS06435
gene id: 1038856:BBI15_RS06435
uniprot id: A0A1C7E5S7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS14105
gene id: 1038856:BBI15_RS14105
uniprot id: A0A1C7E8X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS09935
gene id: 1038856:BBI15_RS09935
uniprot id: A0A1C7E897
names: Similarity
messages: Belongs to the fabD family.

1038856:BBI15 RS10315
gene id: 1038856:BBI15_RS10315
uniprot id: A0A1C7E7Q0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS09725
gene id: 1038856:BBI15_RS09725
uniprot id: A0A1C7E7D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1038856:BBI15 RS08865
gene id: 1038856:BBI15_RS08865
uniprot id: A0A1C7EE76
names: Similarity
messages: Belongs to the peptidase S41A family.

1038856:BBI15 RS07955
gene id: 1038856:BBI15_RS07955
uniprot id: A0A1C7E790
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS12795
gene id: 1038856:BBI15_RS12795
uniprot id: A0A1C7E912
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1038856:BBI15 RS07200
gene id: 1038856:BBI15_RS07200
uniprot id: A0A1C7E5E3
names: Function
messages: Required for transformation and DNA binding.

1038856:BBI15 RS09060
gene id: 1038856:BBI15_RS09060
uniprot id: A0A1C7E7T4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1038856:BBI15 RS07135
gene id: 1038856:BBI15_RS07135
uniprot id: A0A1C7E6S3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1038856:BBI15 RS12450
gene id: 1038856:BBI15_RS12450
uniprot id: A0A1C7E820
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1038856:BBI15 RS05205
gene id: 1038856:BBI15_RS05205
uniprot id: A0A1C7E4F5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1038856:BBI15 RS15915
gene id: 1038856:BBI15_RS15915
uniprot id: A0A1C7EAJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS01885
gene id: 1038856:BBI15_RS01885
uniprot id: A0A1C7EBQ5
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS00030
gene id: 1038856:BBI15_RS00030
uniprot id: A0A1C7EAW3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1038856:BBI15 RS11030
gene id: 1038856:BBI15_RS11030
uniprot id: A0A1C7E8X4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase.
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1038856:BBI15 RS14720
gene id: 1038856:BBI15_RS14720
uniprot id: A0A1C7EA21
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1038856:BBI15 RS14200
gene id: 1038856:BBI15_RS14200
uniprot id: A0A1C7E9W4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1038856:BBI15 RS03755
gene id: 1038856:BBI15_RS03755
uniprot id: A0A1C7ECQ8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1038856:BBI15 RS09500
gene id: 1038856:BBI15_RS09500
uniprot id: A0A1C7E785
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1038856:BBI15 RS07105
gene id: 1038856:BBI15_RS07105
uniprot id: A0A1C7E615
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1038856:BBI15 RS13140
gene id: 1038856:BBI15_RS13140
uniprot id: A0A1C7EA15
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. YrrT family.
messages: Could be a S-adenosyl-L-methionine-dependent methyltransferase.

1038856:BBI15 RS07325
gene id: 1038856:BBI15_RS07325
uniprot id: A0A1C7E6V4
names: Similarity
messages: Belongs to the UPF0735 family.

1038856:BBI15 RS09265
gene id: 1038856:BBI15_RS09265
uniprot id: A0A1C7E798
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1038856:BBI15 RS04920
gene id: 1038856:BBI15_RS04920
uniprot id: A0A1C7E4Z2
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1038856:BBI15 RS11865
gene id: 1038856:BBI15_RS11865
uniprot id: A0A1C7E7Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1038856:BBI15 RS05550
gene id: 1038856:BBI15_RS05550
uniprot id: A0A1C7E5F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

1038856:BBI15 RS02820
gene id: 1038856:BBI15_RS02820
uniprot id: A0A1C7ED13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1038856:BBI15 RS15270
gene id: 1038856:BBI15_RS15270
uniprot id: A0A1C7E9K1
names: Function
names: Subcellular Location Annotation
messages: Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA).
messages: Cytoplasm

1038856:BBI15 RS00005
gene id: 1038856:BBI15_RS00005
uniprot id: A0A1C7EAB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1038856:BBI15 RS05980
gene id: 1038856:BBI15_RS05980
uniprot id: A0A1C7E4S2
names: Similarity
messages: Belongs to the ArsC family.

1038856:BBI15 RS08460
gene id: 1038856:BBI15_RS08460
uniprot id: A0A1C7E607
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Monomer.

1038856:BBI15 RS16035
gene id: 1038856:BBI15_RS16035
uniprot id: A0A1C7EBI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1038856:BBI15 RS10495
gene id: 1038856:BBI15_RS10495
uniprot id: A0A1C7EDB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS07010
gene id: 1038856:BBI15_RS07010
uniprot id: A0A1C7E5Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1038856:BBI15 RS15920
gene id: 1038856:BBI15_RS15920
uniprot id: A0A1C7EA65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS10115
gene id: 1038856:BBI15_RS10115
uniprot id: A0A1C7E776
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1038856:BBI15 RS01840
gene id: 1038856:BBI15_RS01840
uniprot id: A0A1C7ECI1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1038856:BBI15 RS04130
gene id: 1038856:BBI15_RS04130
uniprot id: A0A1C7ECX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1038856:BBI15 RS00525
gene id: 1038856:BBI15_RS00525
uniprot id: A0A1C7EA77
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1038856:BBI15 RS10245
gene id: 1038856:BBI15_RS10245
uniprot id: A0A1C7E7R7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1038856:BBI15 RS02525
gene id: 1038856:BBI15_RS02525
uniprot id: A0A1C7EB65
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1038856:BBI15 RS07125
gene id: 1038856:BBI15_RS07125
uniprot id: A0A1C7E5P7
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1038856:BBI15 RS11570
gene id: 1038856:BBI15_RS11570
uniprot id: A0A1C7E947
names: Function
messages: Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA.

1038856:BBI15 RS14065
gene id: 1038856:BBI15_RS14065
uniprot id: A0A1C7E9T8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1038856:BBI15 RS13975
gene id: 1038856:BBI15_RS13975
uniprot id: A0A1C7E9L7
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1038856:BBI15 RS12885
gene id: 1038856:BBI15_RS12885
uniprot id: A0A1C7E8C2
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1038856:BBI15 RS15785
gene id: 1038856:BBI15_RS15785
uniprot id: A0A1C7EAL3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1038856:BBI15 RS11550
gene id: 1038856:BBI15_RS11550
uniprot id: A0A1C7E7K0
names: Similarity
messages: Belongs to the peptidase S8 family.

1038856:BBI15 RS13045
gene id: 1038856:BBI15_RS13045
uniprot id: A0A1C7E8F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS01195
gene id: 1038856:BBI15_RS01195
uniprot id: A0A1C7EC56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS13305
gene id: 1038856:BBI15_RS13305
uniprot id: A0A1C7E8V6
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1038856:BBI15 RS13005
gene id: 1038856:BBI15_RS13005
uniprot id: A0A1C7E9X3
names: Similarity
messages: Belongs to the ChdC family. Type 1 subfamily.

1038856:BBI15 RS07465
gene id: 1038856:BBI15_RS07465
uniprot id: A0A1C7ECF6
names: Similarity
messages: Belongs to the UPF0297 family.

1038856:BBI15 RS03470
gene id: 1038856:BBI15_RS03470
uniprot id: A0A1C7ECK9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1038856:BBI15 RS09765
gene id: 1038856:BBI15_RS09765
uniprot id: A0A1C7E7G2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1038856:BBI15 RS12180
gene id: 1038856:BBI15_RS12180
uniprot id: A0A1C7E8S7
names: Similarity
messages: Belongs to the peptidase C40 family.

1038856:BBI15 RS10075
gene id: 1038856:BBI15_RS10075
uniprot id: A0A1C7E6V3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

1038856:BBI15 RS07645
gene id: 1038856:BBI15_RS07645
uniprot id: A0A1C7E6E9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

1038856:BBI15 RS15710
gene id: 1038856:BBI15_RS15710
uniprot id: A0A1C7EAM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1038856:BBI15 RS03195
gene id: 1038856:BBI15_RS03195
uniprot id: A0A1C7EBK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1038856:BBI15 RS04720
gene id: 1038856:BBI15_RS04720
uniprot id: A0A1C7E527
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1038856:BBI15 RS04615
gene id: 1038856:BBI15_RS04615
uniprot id: A0A1C7ECC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS01785
gene id: 1038856:BBI15_RS01785
uniprot id: A0A1C7EBN7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1038856:BBI15 RS06980
gene id: 1038856:BBI15_RS06980
uniprot id: A0A1C7E589
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1038856:BBI15 RS04755
gene id: 1038856:BBI15_RS04755
uniprot id: A0A1C7E526
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1038856:BBI15 RS15290
gene id: 1038856:BBI15_RS15290
uniprot id: A0A1C7EAA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1038856:BBI15 RS00495
gene id: 1038856:BBI15_RS00495
uniprot id: A0A1C7EAY0
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1038856:BBI15 RS06680
gene id: 1038856:BBI15_RS06680
uniprot id: A0A1C7E5X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EzrA family.
messages: Cell membrane
messages: Membrane
messages: Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.

1038856:BBI15 RS11235
gene id: 1038856:BBI15_RS11235
uniprot id: A0A1C7E8A3
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS10435
gene id: 1038856:BBI15_RS10435
uniprot id: A0A1C7E8L3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1038856:BBI15 RS02545
gene id: 1038856:BBI15_RS02545
uniprot id: A0A1C7EDF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1038856:BBI15 RS02025
gene id: 1038856:BBI15_RS02025
uniprot id: A0A1C7ECN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1038856:BBI15 RS12435
gene id: 1038856:BBI15_RS12435
uniprot id: A0A1C7E8F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1038856:BBI15 RS11750
gene id: 1038856:BBI15_RS11750
uniprot id: A0A1C7E9A3
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS13380
gene id: 1038856:BBI15_RS13380
uniprot id: A0A1C7E8L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS12670
gene id: 1038856:BBI15_RS12670
uniprot id: A0A1C7E915
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS13990
gene id: 1038856:BBI15_RS13990
uniprot id: A0A1C7E9R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS15500
gene id: 1038856:BBI15_RS15500
uniprot id: A0A1C7E9K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1038856:BBI15 RS02150
gene id: 1038856:BBI15_RS02150
uniprot id: A0A1C7EB16
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS00500
gene id: 1038856:BBI15_RS00500
uniprot id: A0A1C7EAX6
names: Similarity
messages: Belongs to the ycf81 family.

1038856:BBI15 RS06885
gene id: 1038856:BBI15_RS06885
uniprot id: A0A1C7E576
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1038856:BBI15 RS15615
gene id: 1038856:BBI15_RS15615
uniprot id: A0A1C7EAK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1038856:BBI15 RS08330
gene id: 1038856:BBI15_RS08330
uniprot id: A0A1C7E6C7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1038856:BBI15 RS14275
gene id: 1038856:BBI15_RS14275
uniprot id: A0A1C7EDF2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1038856:BBI15 RS07835
gene id: 1038856:BBI15_RS07835
uniprot id: A0A1C7E6J1
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1038856:BBI15 RS15585
gene id: 1038856:BBI15_RS15585
uniprot id: A0A1C7EAE4
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1038856:BBI15 RS15735
gene id: 1038856:BBI15_RS15735
uniprot id: A0A1C7EAJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1038856:BBI15 RS02050
gene id: 1038856:BBI15_RS02050
uniprot id: A0A1C7ECM1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1038856:BBI15 RS11045
gene id: 1038856:BBI15_RS11045
uniprot id: A0A1C7E860
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS01350
gene id: 1038856:BBI15_RS01350
uniprot id: A0A1C7EBC7
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

1038856:BBI15 RS09230
gene id: 1038856:BBI15_RS09230
uniprot id: A0A1C7E754
names: Similarity
messages: Belongs to the UPF0302 family.

1038856:BBI15 RS10730
gene id: 1038856:BBI15_RS10730
uniprot id: A0A1C7E7X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS04650
gene id: 1038856:BBI15_RS04650
uniprot id: A0A1C7E460
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS07760
gene id: 1038856:BBI15_RS07760
uniprot id: A0A1C7E732
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1038856:BBI15 RS00295
gene id: 1038856:BBI15_RS00295
uniprot id: A0A1C7EBR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

1038856:BBI15 RS02420
gene id: 1038856:BBI15_RS02420
uniprot id: A0A1C7EB74
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS07475
gene id: 1038856:BBI15_RS07475
uniprot id: A0A1C7E5I6
names: Similarity
messages: Belongs to the UPF0473 family.

1038856:BBI15 RS06420
gene id: 1038856:BBI15_RS06420
uniprot id: A0A1C7E5L8
names: Similarity
messages: Belongs to the Dps family.

1038856:BBI15 RS01110
gene id: 1038856:BBI15_RS01110
uniprot id: A0A1C7EC64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1038856:BBI15 RS05530
gene id: 1038856:BBI15_RS05530
uniprot id: A0A1C7E5D8
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS15025
gene id: 1038856:BBI15_RS15025
uniprot id: A0A1C7EDF1
names: Similarity
messages: Belongs to the FBPase class 3 family.

1038856:BBI15 RS14000
gene id: 1038856:BBI15_RS14000
uniprot id: A0A1C7E8V1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1038856:BBI15 RS10140
gene id: 1038856:BBI15_RS10140
uniprot id: A0A1C7E7P6
names: Similarity
messages: Belongs to the YggT family.

1038856:BBI15 RS07920
gene id: 1038856:BBI15_RS07920
uniprot id: A0A1C7E6G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1038856:BBI15 RS07060
gene id: 1038856:BBI15_RS07060
uniprot id: A0A1C7E604
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1038856:BBI15 RS11105
gene id: 1038856:BBI15_RS11105
uniprot id: A0A1C7E8W6
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS04390
gene id: 1038856:BBI15_RS04390
uniprot id: A0A1C7EC55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1038856:BBI15 RS15035
gene id: 1038856:BBI15_RS15035
uniprot id: A0A1C7E9D4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS09245
gene id: 1038856:BBI15_RS09245
uniprot id: A0A1C7E791
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1038856:BBI15 RS06500
gene id: 1038856:BBI15_RS06500
uniprot id: A0A1C7E6F2
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS07805
gene id: 1038856:BBI15_RS07805
uniprot id: A0A1C7E6I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1038856:BBI15 RS09985
gene id: 1038856:BBI15_RS09985
uniprot id: A0A1C7E8A6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1038856:BBI15 RS07265
gene id: 1038856:BBI15_RS07265
uniprot id: A0A1C7E645
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1038856:BBI15 RS09085
gene id: 1038856:BBI15_RS09085
uniprot id: A0A1C7E762
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GpsB family.
messages: Cytoplasm
messages: Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
messages: Forms polymers through the coiled coil domains. Interacts with PBP1, MreC and EzrA.

1038856:BBI15 RS05100
gene id: 1038856:BBI15_RS05100
uniprot id: A0A1C7E5T4
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS02535
gene id: 1038856:BBI15_RS02535
uniprot id: A0A1C7EC28
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS02365
gene id: 1038856:BBI15_RS02365
uniprot id: A0A1C7EB36
names: Similarity
messages: Belongs to the WrbA family.

1038856:BBI15 RS12070
gene id: 1038856:BBI15_RS12070
uniprot id: A0A1C7E7W9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1038856:BBI15 RS12950
gene id: 1038856:BBI15_RS12950
uniprot id: A0A1C7E946
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1038856:BBI15 RS14955
gene id: 1038856:BBI15_RS14955
uniprot id: A0A1C7EA32
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1038856:BBI15 RS02445
gene id: 1038856:BBI15_RS02445
uniprot id: A0A1C7EBW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1038856:BBI15 RS08580
gene id: 1038856:BBI15_RS08580
uniprot id: A0A1C7E626
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1038856:BBI15 RS00685
gene id: 1038856:BBI15_RS00685
uniprot id: A0A1C7EAB1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1038856:BBI15 RS00585
gene id: 1038856:BBI15_RS00585
uniprot id: A0A1C7EB40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1038856:BBI15 RS12975
gene id: 1038856:BBI15_RS12975
uniprot id: A0A1C7E971
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1038856:BBI15 RS01150
gene id: 1038856:BBI15_RS01150
uniprot id: A0A1C7EB90
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1038856:BBI15 RS11410
gene id: 1038856:BBI15_RS11410
uniprot id: A0A1C7E896
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1038856:BBI15 RS10525
gene id: 1038856:BBI15_RS10525
uniprot id: A0A1C7E7S7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1038856:BBI15 RS12810
gene id: 1038856:BBI15_RS12810
uniprot id: A0A1C7E901
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1038856:BBI15 RS10815
gene id: 1038856:BBI15_RS10815
uniprot id: A0A1C7E788
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS02315
gene id: 1038856:BBI15_RS02315
uniprot id: A0A1C7EB28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1038856:BBI15 RS04840
gene id: 1038856:BBI15_RS04840
uniprot id: A0A1C7E4A3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1038856:BBI15 RS05610
gene id: 1038856:BBI15_RS05610
uniprot id: A0A1C7E580
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS02660
gene id: 1038856:BBI15_RS02660
uniprot id: A0A1C7ECY0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Central regulator of manganese homeostasis.
messages: Cytoplasm
messages: DNA binding is strongly activated by Mn(2+).
messages: Homodimer.

1038856:BBI15 RS09850
gene id: 1038856:BBI15_RS09850
uniprot id: A0A1C7E6N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1038856:BBI15 RS00505
gene id: 1038856:BBI15_RS00505
uniprot id: A0A1C7EAI0
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1038856:BBI15 RS04625
gene id: 1038856:BBI15_RS04625
uniprot id: A0A1C7E4Y3
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1038856:BBI15 RS10715
gene id: 1038856:BBI15_RS10715
uniprot id: A0A1C7E805
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1038856:BBI15 RS13700
gene id: 1038856:BBI15_RS13700
uniprot id: A0A1C7E9L0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1038856:BBI15 RS13730
gene id: 1038856:BBI15_RS13730
uniprot id: A0A1C7ED89
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1038856:BBI15 RS10615
gene id: 1038856:BBI15_RS10615
uniprot id: A0A1C7E8N1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS15945
gene id: 1038856:BBI15_RS15945
uniprot id: A0A1C7EAR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS00080
gene id: 1038856:BBI15_RS00080
uniprot id: A0A1C7EAW9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS00550
gene id: 1038856:BBI15_RS00550
uniprot id: A0A1C7EAY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1038856:BBI15 RS10340
gene id: 1038856:BBI15_RS10340
uniprot id: A0A1C7E6Y5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

1038856:BBI15 RS13095
gene id: 1038856:BBI15_RS13095
uniprot id: A0A1C7E8D7
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1038856:BBI15 RS01750
gene id: 1038856:BBI15_RS01750
uniprot id: A0A1C7EB48
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

1038856:BBI15 RS00220
gene id: 1038856:BBI15_RS00220
uniprot id: A0A1C7EBR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1038856:BBI15 RS00065
gene id: 1038856:BBI15_RS00065
uniprot id: A0A1C7EAS2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1038856:BBI15 RS08790
gene id: 1038856:BBI15_RS08790
uniprot id: A0A1C7E6X8
names: Subcellular Location Annotation
messages: Cytoplasm

1038856:BBI15 RS04190
gene id: 1038856:BBI15_RS04190
uniprot id: A0A1C7EDR9
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1038856:BBI15 RS00670
gene id: 1038856:BBI15_RS00670
uniprot id: A0A1C7EB63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1038856:BBI15 RS07970
gene id: 1038856:BBI15_RS07970
uniprot id: A0A1C7E6L3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1038856:BBI15 RS02010
gene id: 1038856:BBI15_RS02010
uniprot id: A0A1C7EBN4
names: Similarity
messages: Belongs to the UPF0178 family.

1038856:BBI15 RS15200
gene id: 1038856:BBI15_RS15200
uniprot id: A0A1C7E9G1
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS03680
gene id: 1038856:BBI15_RS03680
uniprot id: A0A1C7EBS9
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

1038856:BBI15 RS00890
gene id: 1038856:BBI15_RS00890
uniprot id: A0A1C7EB89
names: Similarity
messages: Belongs to the citrate synthase family.

1038856:BBI15 RS10920
gene id: 1038856:BBI15_RS10920
uniprot id: A0A1C7E8V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1038856:BBI15 RS12320
gene id: 1038856:BBI15_RS12320
uniprot id: A0A1C7E8R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS12235
gene id: 1038856:BBI15_RS12235
uniprot id: A0A1C7EEA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1038856:BBI15 RS12465
gene id: 1038856:BBI15_RS12465
uniprot id: A0A1C7E8V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

1038856:BBI15 RS06160
gene id: 1038856:BBI15_RS06160
uniprot id: A0A1C7E4V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

1038856:BBI15 RS02895
gene id: 1038856:BBI15_RS02895
uniprot id: A0A1C7EBR0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1038856:BBI15 RS00780
gene id: 1038856:BBI15_RS00780
uniprot id: A0A1C7EAA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1038856:BBI15 RS05665
gene id: 1038856:BBI15_RS05665
uniprot id: A0A1C7E590
names: Similarity
messages: Belongs to the peptidase S9C family.

1038856:BBI15 RS04870
gene id: 1038856:BBI15_RS04870
uniprot id: A0A1C7E4Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1038856:BBI15 RS06710
gene id: 1038856:BBI15_RS06710
uniprot id: A0A1C7E5T5
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS01875
gene id: 1038856:BBI15_RS01875
uniprot id: A0A1C7EAX3
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

1038856:BBI15 RS12745
gene id: 1038856:BBI15_RS12745
uniprot id: A0A1C7E905
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS09425
gene id: 1038856:BBI15_RS09425
uniprot id: A0A1C7E6J7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1038856:BBI15 RS13940
gene id: 1038856:BBI15_RS13940
uniprot id: A0A1C7E9Q4
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS00595
gene id: 1038856:BBI15_RS00595
uniprot id: A0A1C7EBV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1038856:BBI15 RS00490
gene id: 1038856:BBI15_RS00490
uniprot id: A0A1C7EBT4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1038856:BBI15 RS10725
gene id: 1038856:BBI15_RS10725
uniprot id: A0A1C7E8P6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1038856:BBI15 RS13880
gene id: 1038856:BBI15_RS13880
uniprot id: A0A1C7E958
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS15905
gene id: 1038856:BBI15_RS15905
uniprot id: A0A1C7EBG1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1038856:BBI15 RS13690
gene id: 1038856:BBI15_RS13690
uniprot id: A0A1C7E920
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1038856:BBI15 RS05775
gene id: 1038856:BBI15_RS05775
uniprot id: A0A1C7E647
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1038856:BBI15 RS07030
gene id: 1038856:BBI15_RS07030
uniprot id: A0A1C7E5A5
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1038856:BBI15 RS12250
gene id: 1038856:BBI15_RS12250
uniprot id: A0A1C7E8Q0
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS14145
gene id: 1038856:BBI15_RS14145
uniprot id: A0A1C7E9A6
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1038856:BBI15 RS06860
gene id: 1038856:BBI15_RS06860
uniprot id: A0A1C7E5W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1038856:BBI15 RS09410
gene id: 1038856:BBI15_RS09410
uniprot id: A0A1C7E7B9
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS00710
gene id: 1038856:BBI15_RS00710
uniprot id: A0A1C7EB18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1038856:BBI15 RS07915
gene id: 1038856:BBI15_RS07915
uniprot id: A0A1C7E6K1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1038856:BBI15 RS05035
gene id: 1038856:BBI15_RS05035
uniprot id: A0A1C7E4T6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1038856:BBI15 RS09470
gene id: 1038856:BBI15_RS09470
uniprot id: A0A1C7E6H3
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1038856:BBI15 RS10015
gene id: 1038856:BBI15_RS10015
uniprot id: A0A1C7E6R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1038856:BBI15 RS03630
gene id: 1038856:BBI15_RS03630
uniprot id: A0A1C7EBU7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS01005
gene id: 1038856:BBI15_RS01005
uniprot id: A0A1C7EC39
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS14245
gene id: 1038856:BBI15_RS14245
uniprot id: A0A1C7E9C3
names: Similarity
messages: Belongs to the catalase family.

1038856:BBI15 RS09860
gene id: 1038856:BBI15_RS09860
uniprot id: A0A1C7E6R8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1038856:BBI15 RS00100
gene id: 1038856:BBI15_RS00100
uniprot id: A0A1C7EA17
names: Similarity
messages: Belongs to the DCK/DGK family.

1038856:BBI15 RS14155
gene id: 1038856:BBI15_RS14155
uniprot id: A0A1C7EAK7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

1038856:BBI15 RS06830
gene id: 1038856:BBI15_RS06830
uniprot id: A0A1C7E560
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1038856:BBI15 RS15345
gene id: 1038856:BBI15_RS15345
uniprot id: A0A1C7EAB8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1038856:BBI15 RS13150
gene id: 1038856:BBI15_RS13150
uniprot id: A0A1C7E8E8
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1038856:BBI15 RS12935
gene id: 1038856:BBI15_RS12935
uniprot id: A0A1C7E8A8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1038856:BBI15 RS07510
gene id: 1038856:BBI15_RS07510
uniprot id: A0A1C7E681
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1038856:BBI15 RS12865
gene id: 1038856:BBI15_RS12865
uniprot id: A0A1C7E8N0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS05870
gene id: 1038856:BBI15_RS05870
uniprot id: A0A1C7E4R3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1038856:BBI15 RS00070
gene id: 1038856:BBI15_RS00070
uniprot id: A0A1C7EAR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1038856:BBI15 RS10610
gene id: 1038856:BBI15_RS10610
uniprot id: A0A1C7E7X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1038856:BBI15 RS02325
gene id: 1038856:BBI15_RS02325
uniprot id: A0A1C7EBY9
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1038856:BBI15 RS07600
gene id: 1038856:BBI15_RS07600
uniprot id: A0A1C7E6A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1038856:BBI15 RS07790
gene id: 1038856:BBI15_RS07790
uniprot id: A0A1C7E756
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1038856:BBI15 RS10200
gene id: 1038856:BBI15_RS10200
uniprot id: A0A1C7E8E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

1038856:BBI15 RS00920
gene id: 1038856:BBI15_RS00920
uniprot id: A0A1C7ECS3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1038856:BBI15 RS02490
gene id: 1038856:BBI15_RS02490
uniprot id: A0A1C7ECU8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS01710
gene id: 1038856:BBI15_RS01710
uniprot id: A0A1C7EAU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1038856:BBI15 RS11855
gene id: 1038856:BBI15_RS11855
uniprot id: A0A1C7E8L7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

1038856:BBI15 RS15860
gene id: 1038856:BBI15_RS15860
uniprot id: A0A1C7EA57
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1038856:BBI15 RS07080
gene id: 1038856:BBI15_RS07080
uniprot id: A0A1C7ECP5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1038856:BBI15 RS08250
gene id: 1038856:BBI15_RS08250
uniprot id: A0A1C7E5Z5
names: Similarity
messages: Belongs to the UPF0045 family.

1038856:BBI15 RS10970
gene id: 1038856:BBI15_RS10970
uniprot id: A0A1C7E856
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS06735
gene id: 1038856:BBI15_RS06735
uniprot id: A0A1C7E546
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS07300
gene id: 1038856:BBI15_RS07300
uniprot id: A0A1C7E6V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1038856:BBI15 RS01925
gene id: 1038856:BBI15_RS01925
uniprot id: A0A1C7EAW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1038856:BBI15 RS09460
gene id: 1038856:BBI15_RS09460
uniprot id: A0A1C7E7C8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1038856:BBI15 RS00720
gene id: 1038856:BBI15_RS00720
uniprot id: A0A1C7EB73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1038856:BBI15 RS08610
gene id: 1038856:BBI15_RS08610
uniprot id: A0A1C7E6V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

1038856:BBI15 RS09665
gene id: 1038856:BBI15_RS09665
uniprot id: A0A1C7E844
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS05220
gene id: 1038856:BBI15_RS05220
uniprot id: A0A1C7E5B2
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1038856:BBI15 RS01205
gene id: 1038856:BBI15_RS01205
uniprot id: A0A1C7EBA0
names: Similarity
messages: Belongs to the FlgD family.

1038856:BBI15 RS02825
gene id: 1038856:BBI15_RS02825
uniprot id: A0A1C7EC36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1038856:BBI15 RS08365
gene id: 1038856:BBI15_RS08365
uniprot id: A0A1C7E6U7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.
messages: Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS00665
gene id: 1038856:BBI15_RS00665
uniprot id: A0A1C7EAL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1038856:BBI15 RS10225
gene id: 1038856:BBI15_RS10225
uniprot id: A0A1C7E7S3
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1038856:BBI15 RS06025
gene id: 1038856:BBI15_RS06025
uniprot id: A0A1C7E5M6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1038856:BBI15 RS00300
gene id: 1038856:BBI15_RS00300
uniprot id: A0A1C7EAW0
names: Similarity
messages: Belongs to the CarB family.

1038856:BBI15 RS10385
gene id: 1038856:BBI15_RS10385
uniprot id: A0A1C7E8K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1038856:BBI15 RS00995
gene id: 1038856:BBI15_RS00995
uniprot id: A0A1C7EAQ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. ABCF family. ARE2 subfamily.
messages: Binds within the E-site of the 70S ribosome, where it contacts ribosomal proteins of the large and small subunit, the 16 and 23S rRNAs and the acceptor arm of the P-site tRNA.
messages: Cytoplasm
messages: Recognizes and binds in the vacant E-site of ribosomes stalled by some peptidyltransferase center (PTC)-targeting antibiotics. Makes contact with the PTC and both ribosomal subunits. Induces conformational changes in the P-site, which allows it to dislodge the antibiotic from its PTC binding site.
messages: The antibiotic resistance domain (ARD) is packed between the 23S rRNA and the acceptor arm of the P-site tRNA and inserts into the peptidyltransferase center (PTC). The C-terminal extension (CTE) contacts the small ribosomal subunit, positioned in the Shine-Dalgarno-anti-Shine-Dalgarno cavity.

1038856:BBI15 RS09900
gene id: 1038856:BBI15_RS09900
uniprot id: A0A1C7E7K7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1038856:BBI15 RS04035
gene id: 1038856:BBI15_RS04035
uniprot id: A0A1C7ECP1
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS09385
gene id: 1038856:BBI15_RS09385
uniprot id: A0A1C7E797
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1038856:BBI15 RS09870
gene id: 1038856:BBI15_RS09870
uniprot id: A0A1C7E7I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS07860
gene id: 1038856:BBI15_RS07860
uniprot id: A0A1C7E6F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1038856:BBI15 RS10040
gene id: 1038856:BBI15_RS10040
uniprot id: A0A1C7E7J8
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1038856:BBI15 RS08965
gene id: 1038856:BBI15_RS08965
uniprot id: A0A1C7E6Z6
names: Subcellular Location Annotation
messages: Cytoplasm

1038856:BBI15 RS04935
gene id: 1038856:BBI15_RS04935
uniprot id: A0A1C7E5P5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1038856:BBI15 RS12710
gene id: 1038856:BBI15_RS12710
uniprot id: A0A1C7E8Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1038856:BBI15 RS15980
gene id: 1038856:BBI15_RS15980
uniprot id: A0A1C7EBI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS07865
gene id: 1038856:BBI15_RS07865
uniprot id: A0A1C7E755
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ComGC family.
messages: Cell membrane
messages: Homodimer.
messages: Required for transformation and DNA binding.

1038856:BBI15 RS07960
gene id: 1038856:BBI15_RS07960
uniprot id: A0A1C7E5R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1038856:BBI15 RS11355
gene id: 1038856:BBI15_RS11355
uniprot id: A0A1C7E7V3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1038856:BBI15 RS10260
gene id: 1038856:BBI15_RS10260
uniprot id: A0A1C7E8F9
names: Similarity
messages: Belongs to the peptidase S16 family.

1038856:BBI15 RS06925
gene id: 1038856:BBI15_RS06925
uniprot id: A0A1C7E6N5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1038856:BBI15 RS05410
gene id: 1038856:BBI15_RS05410
uniprot id: A0A1C7E4Y5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1038856:BBI15 RS00715
gene id: 1038856:BBI15_RS00715
uniprot id: A0A1C7EAL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1038856:BBI15 RS07610
gene id: 1038856:BBI15_RS07610
uniprot id: A0A1C7E6C3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1038856:BBI15 RS12615
gene id: 1038856:BBI15_RS12615
uniprot id: A0A1C7E850
names: Similarity
messages: Belongs to the peptidase C40 family.

1038856:BBI15 RS07640
gene id: 1038856:BBI15_RS07640
uniprot id: A0A1C7E5M2
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS02225
gene id: 1038856:BBI15_RS02225
uniprot id: A0A1C7EBW7
names: Similarity
messages: Belongs to the universal stress protein A family.

1038856:BBI15 RS06725
gene id: 1038856:BBI15_RS06725
uniprot id: A0A1C7E6J2
names: Similarity
messages: Belongs to the universal stress protein A family.

1038856:BBI15 RS13755
gene id: 1038856:BBI15_RS13755
uniprot id: A0A1C7E938
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1038856:BBI15 RS12530
gene id: 1038856:BBI15_RS12530
uniprot id: A0A1C7E8U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS01675
gene id: 1038856:BBI15_RS01675
uniprot id: A0A1C7EBI4
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1038856:BBI15 RS01695
gene id: 1038856:BBI15_RS01695
uniprot id: A0A1C7ECH0
names: Cofactor
messages: Binds 1 FAD per subunit.

1038856:BBI15 RS07440
gene id: 1038856:BBI15_RS07440
uniprot id: A0A1C7E6X5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1038856:BBI15 RS00055
gene id: 1038856:BBI15_RS00055
uniprot id: A0A1C7EBM5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1038856:BBI15 RS00610
gene id: 1038856:BBI15_RS00610
uniprot id: A0A1C7EAK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1038856:BBI15 RS11240
gene id: 1038856:BBI15_RS11240
uniprot id: A0A1C7E914
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS13470
gene id: 1038856:BBI15_RS13470
uniprot id: A0A1C7E8Y3
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1038856:BBI15 RS12060
gene id: 1038856:BBI15_RS12060
uniprot id: A0A1C7E9G7
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1038856:BBI15 RS08800
gene id: 1038856:BBI15_RS08800
uniprot id: A0A1C7E6J9
names: Similarity
messages: Belongs to the TelA family.

1038856:BBI15 RS00515
gene id: 1038856:BBI15_RS00515
uniprot id: A0A1C7EBU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1038856:BBI15 RS10455
gene id: 1038856:BBI15_RS10455
uniprot id: A0A1C7E7U1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1038856:BBI15 RS09430
gene id: 1038856:BBI15_RS09430
uniprot id: A0A1C7E7C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

1038856:BBI15 RS09880
gene id: 1038856:BBI15_RS09880
uniprot id: A0A1C7EE87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1038856:BBI15 RS07615
gene id: 1038856:BBI15_RS07615
uniprot id: A0A1C7E698
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1038856:BBI15 RS09720
gene id: 1038856:BBI15_RS09720
uniprot id: A0A1C7E857
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1038856:BBI15 RS15060
gene id: 1038856:BBI15_RS15060
uniprot id: A0A1C7EA66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS11140
gene id: 1038856:BBI15_RS11140
uniprot id: A0A1C7E7C9
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1038856:BBI15 RS14470
gene id: 1038856:BBI15_RS14470
uniprot id: A0A1C7EA09
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS00485
gene id: 1038856:BBI15_RS00485
uniprot id: A0A1C7EB08
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

1038856:BBI15 RS00765
gene id: 1038856:BBI15_RS00765
uniprot id: A0A1C7EAM8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1038856:BBI15 RS00790
gene id: 1038856:BBI15_RS00790
uniprot id: A0A1C7EB78
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1038856:BBI15 RS02520
gene id: 1038856:BBI15_RS02520
uniprot id: A0A1C7EEI1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1038856:BBI15 RS07355
gene id: 1038856:BBI15_RS07355
uniprot id: A0A1C7E6W8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1038856:BBI15 RS12205
gene id: 1038856:BBI15_RS12205
uniprot id: A0A1C7E8B4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

1038856:BBI15 RS03795
gene id: 1038856:BBI15_RS03795
uniprot id: A0A1C7EBX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1038856:BBI15 RS06715
gene id: 1038856:BBI15_RS06715
uniprot id: A0A1C7E5I1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1038856:BBI15 RS06010
gene id: 1038856:BBI15_RS06010
uniprot id: A0A1C7E5L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1038856:BBI15 RS15475
gene id: 1038856:BBI15_RS15475
uniprot id: A0A1C7EAD6
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1038856:BBI15 RS07085
gene id: 1038856:BBI15_RS07085
uniprot id: A0A1C7E5B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1038856:BBI15 RS07710
gene id: 1038856:BBI15_RS07710
uniprot id: A0A1C7E723
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1038856:BBI15 RS10080
gene id: 1038856:BBI15_RS10080
uniprot id: A0A1C7E7N8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1038856:BBI15 RS07290
gene id: 1038856:BBI15_RS07290
uniprot id: A0A1C7E5T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1038856:BBI15 RS09400
gene id: 1038856:BBI15_RS09400
uniprot id: A0A1C7E770
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS02870
gene id: 1038856:BBI15_RS02870
uniprot id: A0A1C7EC77
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1038856:BBI15 RS07715
gene id: 1038856:BBI15_RS07715
uniprot id: A0A1C7E6E4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1038856:BBI15 RS00345
gene id: 1038856:BBI15_RS00345
uniprot id: A0A1C7EB12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1038856:BBI15 RS10410
gene id: 1038856:BBI15_RS10410
uniprot id: A0A1C7E8I9
names: Similarity
messages: Belongs to the UPF0223 family.

1038856:BBI15 RS10045
gene id: 1038856:BBI15_RS10045
uniprot id: A0A1C7ECD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS05855
gene id: 1038856:BBI15_RS05855
uniprot id: A0A1C7E5J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1038856:BBI15 RS15715
gene id: 1038856:BBI15_RS15715
uniprot id: A0A1C7EBD3
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS03040
gene id: 1038856:BBI15_RS03040
uniprot id: A0A1C7ED46
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1038856:BBI15 RS06910
gene id: 1038856:BBI15_RS06910
uniprot id: A0A1C7E5X3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS02590
gene id: 1038856:BBI15_RS02590
uniprot id: A0A1C7EC35
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1038856:BBI15 RS14935
gene id: 1038856:BBI15_RS14935
uniprot id: A0A1C7EA61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1038856:BBI15 RS01210
gene id: 1038856:BBI15_RS01210
uniprot id: A0A1C7EAU8
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1038856:BBI15 RS09275
gene id: 1038856:BBI15_RS09275
uniprot id: A0A1C7EE56
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1038856:BBI15 RS00915
gene id: 1038856:BBI15_RS00915
uniprot id: A0A1C7EB53
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

1038856:BBI15 RS07635
gene id: 1038856:BBI15_RS07635
uniprot id: A0A1C7E5L5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1038856:BBI15 RS02730
gene id: 1038856:BBI15_RS02730
uniprot id: A0A1C7EBN2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS11535
gene id: 1038856:BBI15_RS11535
uniprot id: A0A1C7E7Y3
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS11845
gene id: 1038856:BBI15_RS11845
uniprot id: A0A1C7E8I0
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

1038856:BBI15 RS15740
gene id: 1038856:BBI15_RS15740
uniprot id: A0A1C7EBC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1038856:BBI15 RS15575
gene id: 1038856:BBI15_RS15575
uniprot id: A0A1C7EB99
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1038856:BBI15 RS06460
gene id: 1038856:BBI15_RS06460
uniprot id: A0A1C7E4Z4
names: Similarity
messages: Belongs to the TPP enzyme family.

1038856:BBI15 RS14590
gene id: 1038856:BBI15_RS14590
uniprot id: A0A1C7E959
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS10360
gene id: 1038856:BBI15_RS10360
uniprot id: A0A1C7E8H6
names: Similarity
messages: Belongs to the UPF0358 family.

1038856:BBI15 RS09315
gene id: 1038856:BBI15_RS09315
uniprot id: A0A1C7E7Z7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1038856:BBI15 RS07505
gene id: 1038856:BBI15_RS07505
uniprot id: A0A1C7E6A5
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

1038856:BBI15 RS00775
gene id: 1038856:BBI15_RS00775
uniprot id: A0A1C7EC00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1038856:BBI15 RS05765
gene id: 1038856:BBI15_RS05765
uniprot id: A0A1C7E5I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1038856:BBI15 RS05225
gene id: 1038856:BBI15_RS05225
uniprot id: A0A1C7E530
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1038856:BBI15 RS03535
gene id: 1038856:BBI15_RS03535
uniprot id: A0A1C7ECF8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

1038856:BBI15 RS02720
gene id: 1038856:BBI15_RS02720
uniprot id: A0A1C7EC17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1038856:BBI15 RS16190
gene id: 1038856:BBI15_RS16190
uniprot id: A0A1C7EEC9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS07930
gene id: 1038856:BBI15_RS07930
uniprot id: A0A1C7E6I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1038856:BBI15 RS12775
gene id: 1038856:BBI15_RS12775
uniprot id: A0A1C7E9U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1038856:BBI15 RS03450
gene id: 1038856:BBI15_RS03450
uniprot id: A0A1C7EDG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1038856:BBI15 RS10195
gene id: 1038856:BBI15_RS10195
uniprot id: A0A1C7E7N9
names: Similarity
messages: Belongs to the transpeptidase family.

1038856:BBI15 RS06880
gene id: 1038856:BBI15_RS06880
uniprot id: A0A1C7E570
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1038856:BBI15 RS07340
gene id: 1038856:BBI15_RS07340
uniprot id: A0A1C7E5T9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1038856:BBI15 RS02375
gene id: 1038856:BBI15_RS02375
uniprot id: A0A1C7EBZ8
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS05395
gene id: 1038856:BBI15_RS05395
uniprot id: A0A1C7E5Y0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1038856:BBI15 RS04440
gene id: 1038856:BBI15_RS04440
uniprot id: A0A1C7EC61
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1038856:BBI15 RS06225
gene id: 1038856:BBI15_RS06225
uniprot id: A0A1C7E4W0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. RocA subfamily.

1038856:BBI15 RS02240
gene id: 1038856:BBI15_RS02240
uniprot id: A0A1C7EBS4
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS07050
gene id: 1038856:BBI15_RS07050
uniprot id: A0A1C7E6Q5
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1038856:BBI15 RS07310
gene id: 1038856:BBI15_RS07310
uniprot id: A0A1C7E5F8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1038856:BBI15 RS12735
gene id: 1038856:BBI15_RS12735
uniprot id: A0A1C7E894
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1038856:BBI15 RS04165
gene id: 1038856:BBI15_RS04165
uniprot id: A0A1C7EDU5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1038856:BBI15 RS00520
gene id: 1038856:BBI15_RS00520
uniprot id: A0A1C7EA55
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1038856:BBI15 RS09335
gene id: 1038856:BBI15_RS09335
uniprot id: A0A1C7E786
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1038856:BBI15 RS14040
gene id: 1038856:BBI15_RS14040
uniprot id: A0A1C7E987
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1038856:BBI15 RS12875
gene id: 1038856:BBI15_RS12875
uniprot id: A0A1C7E9W1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1038856:BBI15 RS10335
gene id: 1038856:BBI15_RS10335
uniprot id: A0A1C7E8J4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1038856:BBI15 RS15890
gene id: 1038856:BBI15_RS15890
uniprot id: A0A1C7E9U8
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS12855
gene id: 1038856:BBI15_RS12855
uniprot id: A0A1C7E908
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

1038856:BBI15 RS00250
gene id: 1038856:BBI15_RS00250
uniprot id: A0A1C7EAV5
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1038856:BBI15 RS13085
gene id: 1038856:BBI15_RS13085
uniprot id: A0A1C7E993
names: Subcellular Location Annotation
messages: Cell membrane

1038856:BBI15 RS08025
gene id: 1038856:BBI15_RS08025
uniprot id: A0A1C7E6I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1038856:BBI15 RS04380
gene id: 1038856:BBI15_RS04380
uniprot id: A0A1C7ED14
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1038856:BBI15 RS15315
gene id: 1038856:BBI15_RS15315
uniprot id: A0A1C7E9H9
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

1038856:BBI15 RS12960
gene id: 1038856:BBI15_RS12960
uniprot id: A0A1C7E926
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1038856:BBI15 RS02920
gene id: 1038856:BBI15_RS02920
uniprot id: A0A1C7EC86
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

1038856:BBI15 RS16145
gene id: 1038856:BBI15_RS16145
uniprot id: A0A1C7ECR3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1038856:BBI15 RS16165
gene id: 1038856:BBI15_RS16165
uniprot id: A0A1C7E9X1
names: Similarity
messages: Belongs to the ParB family.

1038856:BBI15 RS09450
gene id: 1038856:BBI15_RS09450
uniprot id: A0A1C7E779
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1038856:BBI15 RS00705
gene id: 1038856:BBI15_RS00705
uniprot id: A0A1C7EB22
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1038856:BBI15 RS12785
gene id: 1038856:BBI15_RS12785
uniprot id: A0A1C7E8A1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1038856:BBI15 RS10795
gene id: 1038856:BBI15_RS10795
uniprot id: A0A1C7E825
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS07935
gene id: 1038856:BBI15_RS07935
uniprot id: A0A1C7E6F9
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1038856:BBI15 RS06480
gene id: 1038856:BBI15_RS06480
uniprot id: A0A1C7E5R6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1038856:BBI15 RS05815
gene id: 1038856:BBI15_RS05815
uniprot id: A0A1C7E4Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1038856:BBI15 RS01165
gene id: 1038856:BBI15_RS01165
uniprot id: A0A1C7EC76
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1038856:BBI15 RS06945
gene id: 1038856:BBI15_RS06945
uniprot id: A0A1C7E5Y3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1038856:BBI15 RS12715
gene id: 1038856:BBI15_RS12715
uniprot id: A0A1C7E8K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1038856:BBI15 RS01405
gene id: 1038856:BBI15_RS01405
uniprot id: A0A1C7EBD5
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS01445
gene id: 1038856:BBI15_RS01445
uniprot id: A0A1C7EBI2
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS07460
gene id: 1038856:BBI15_RS07460
uniprot id: A0A1C7E6B9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1038856:BBI15 RS02630
gene id: 1038856:BBI15_RS02630
uniprot id: A0A1C7ED37
names: Similarity
messages: Belongs to the peptidase S58 family.

1038856:BBI15 RS11520
gene id: 1038856:BBI15_RS11520
uniprot id: A0A1C7E936
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1038856:BBI15 RS11645
gene id: 1038856:BBI15_RS11645
uniprot id: A0A1C7E986
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

1038856:BBI15 RS00800
gene id: 1038856:BBI15_RS00800
uniprot id: A0A1C7EBZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1038856:BBI15 RS07720
gene id: 1038856:BBI15_RS07720
uniprot id: A0A1C7E6B8
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1038856:BBI15 RS05490
gene id: 1038856:BBI15_RS05490
uniprot id: A0A1C7E4K5
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS13135
gene id: 1038856:BBI15_RS13135
uniprot id: A0A1C7E9A9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1038856:BBI15 RS14630
gene id: 1038856:BBI15_RS14630
uniprot id: A0A1C7E9I6
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS07385
gene id: 1038856:BBI15_RS07385
uniprot id: A0A1C7E6W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1038856:BBI15 RS06865
gene id: 1038856:BBI15_RS06865
uniprot id: A0A1C7E5L0
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1038856:BBI15 RS09925
gene id: 1038856:BBI15_RS09925
uniprot id: A0A1C7E7L3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1038856:BBI15 RS04505
gene id: 1038856:BBI15_RS04505
uniprot id: A0A1C7ECA6
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS12825
gene id: 1038856:BBI15_RS12825
uniprot id: A0A1C7E9V2
names: Similarity
messages: Belongs to the FBPase class 2 family.

1038856:BBI15 RS14760
gene id: 1038856:BBI15_RS14760
uniprot id: A0A1C7E9B5
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

1038856:BBI15 RS08215
gene id: 1038856:BBI15_RS08215
uniprot id: A0A1C7E7C4
names: Subcellular Location Annotation
messages: Cell membrane

1038856:BBI15 RS09685
gene id: 1038856:BBI15_RS09685
uniprot id: A0A1C7E7G7
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1038856:BBI15 RS03385
gene id: 1038856:BBI15_RS03385
uniprot id: A0A1C7EC04
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS08870
gene id: 1038856:BBI15_RS08870
uniprot id: A0A1C7E669
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1038856:BBI15 RS11400
gene id: 1038856:BBI15_RS11400
uniprot id: A0A1C7ECJ5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1038856:BBI15 RS02740
gene id: 1038856:BBI15_RS02740
uniprot id: A0A1C7EC69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1038856:BBI15 RS11250
gene id: 1038856:BBI15_RS11250
uniprot id: A0A1C7E7F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1038856:BBI15 RS05715
gene id: 1038856:BBI15_RS05715
uniprot id: A0A1C7E5A3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1038856:BBI15 RS01400
gene id: 1038856:BBI15_RS01400
uniprot id: A0A1C7EBE3
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS05885
gene id: 1038856:BBI15_RS05885
uniprot id: A0A1C7E5D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1038856:BBI15 RS12370
gene id: 1038856:BBI15_RS12370
uniprot id: A0A1C7E9J3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS07230
gene id: 1038856:BBI15_RS07230
uniprot id: A0A1C7E632
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS07745
gene id: 1038856:BBI15_RS07745
uniprot id: A0A1C7E5P0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1038856:BBI15 RS14310
gene id: 1038856:BBI15_RS14310
uniprot id: A0A1C7E9Y3
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1038856:BBI15 RS04940
gene id: 1038856:BBI15_RS04940
uniprot id: A0A1C7E4B1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1038856:BBI15 RS04535
gene id: 1038856:BBI15_RS04535
uniprot id: A0A1C7ECL0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS16195
gene id: 1038856:BBI15_RS16195
uniprot id: A0A1C7EBL7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS14100
gene id: 1038856:BBI15_RS14100
uniprot id: A0A1C7EAJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS10890
gene id: 1038856:BBI15_RS10890
uniprot id: A0A1C7E817
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0344 family.
messages: Cell membrane

1038856:BBI15 RS10170
gene id: 1038856:BBI15_RS10170
uniprot id: A0A1C7E7R2
names: Similarity
messages: Belongs to the UPF0749 family.

1038856:BBI15 RS04995
gene id: 1038856:BBI15_RS04995
uniprot id: A0A1C7E5R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS06615
gene id: 1038856:BBI15_RS06615
uniprot id: A0A1C7EE24
names: Similarity
messages: Belongs to the histone deacetylase family.

1038856:BBI15 RS11330
gene id: 1038856:BBI15_RS11330
uniprot id: A0A1C7E8B3
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS08385
gene id: 1038856:BBI15_RS08385
uniprot id: A0A1C7E6R5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS00010
gene id: 1038856:BBI15_RS00010
uniprot id: A0A1C7EAV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1038856:BBI15 RS07395
gene id: 1038856:BBI15_RS07395
uniprot id: A0A1C7E660
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1038856:BBI15 RS04565
gene id: 1038856:BBI15_RS04565
uniprot id: A0A1C7ED45
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1038856:BBI15 RS06915
gene id: 1038856:BBI15_RS06915
uniprot id: A0A1C7E5M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1038856:BBI15 RS08590
gene id: 1038856:BBI15_RS08590
uniprot id: A0A1C7E6X9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1038856:BBI15 RS13355
gene id: 1038856:BBI15_RS13355
uniprot id: A0A1C7E9A7
names: Similarity
messages: Belongs to the EamA transporter family.

1038856:BBI15 RS09885
gene id: 1038856:BBI15_RS09885
uniprot id: A0A1C7E7G6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1038856:BBI15 RS11560
gene id: 1038856:BBI15_RS11560
uniprot id: A0A1C7E8G0
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

1038856:BBI15 RS02505
gene id: 1038856:BBI15_RS02505
uniprot id: A0A1C7EBJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS10470
gene id: 1038856:BBI15_RS10470
uniprot id: A0A1C7E7S0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1038856:BBI15 RS08915
gene id: 1038856:BBI15_RS08915
uniprot id: A0A1C7E730
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS04135
gene id: 1038856:BBI15_RS04135
uniprot id: A0A1C7EDR3
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS00740
gene id: 1038856:BBI15_RS00740
uniprot id: A0A1C7EB70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1038856:BBI15 RS00195
gene id: 1038856:BBI15_RS00195
uniprot id: A0A1C7EBP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1038856:BBI15 RS02560
gene id: 1038856:BBI15_RS02560
uniprot id: A0A1C7EBY0
names: Similarity
messages: Belongs to the peptidase C56 family.

1038856:BBI15 RS06255
gene id: 1038856:BBI15_RS06255
uniprot id: A0A1C7E5Q4
names: Similarity
messages: Belongs to the EamA transporter family.

1038856:BBI15 RS14580
gene id: 1038856:BBI15_RS14580
uniprot id: A0A1C7EA30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

1038856:BBI15 RS12940
gene id: 1038856:BBI15_RS12940
uniprot id: A0A1C7E8D4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1038856:BBI15 RS13030
gene id: 1038856:BBI15_RS13030
uniprot id: A0A1C7E981
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1038856:BBI15 RS05760
gene id: 1038856:BBI15_RS05760
uniprot id: A0A1C7E4P9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1038856:BBI15 RS16185
gene id: 1038856:BBI15_RS16185
uniprot id: A0A1C7EAT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1038856:BBI15 RS14410
gene id: 1038856:BBI15_RS14410
uniprot id: A0A1C7E9F3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1038856:BBI15 RS13770
gene id: 1038856:BBI15_RS13770
uniprot id: A0A1C7E8R1
names: Similarity
messages: Belongs to the manganese catalase family.

1038856:BBI15 RS01310
gene id: 1038856:BBI15_RS01310
uniprot id: A0A1C7EAW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
messages: Homodimer.

1038856:BBI15 RS02110
gene id: 1038856:BBI15_RS02110
uniprot id: A0A1C7ECN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1038856:BBI15 RS05970
gene id: 1038856:BBI15_RS05970
uniprot id: A0A1C7E5L9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1038856:BBI15 RS00950
gene id: 1038856:BBI15_RS00950
uniprot id: A0A1C7EDI1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS15870
gene id: 1038856:BBI15_RS15870
uniprot id: A0A1C7EAQ4
names: Similarity
messages: Belongs to the LOR family.

1038856:BBI15 RS07360
gene id: 1038856:BBI15_RS07360
uniprot id: A0A1C7E5G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1038856:BBI15 RS15940
gene id: 1038856:BBI15_RS15940
uniprot id: A0A1C7E9V9
names: Subcellular Location Annotation
messages: Cell membrane

1038856:BBI15 RS10025
gene id: 1038856:BBI15_RS10025
uniprot id: A0A1C7E7N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1038856:BBI15 RS08115
gene id: 1038856:BBI15_RS08115
uniprot id: A0A1C7E6N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1038856:BBI15 RS02555
gene id: 1038856:BBI15_RS02555
uniprot id: A0A1C7EBY6
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1038856:BBI15 RS02380
gene id: 1038856:BBI15_RS02380
uniprot id: A0A1C7EBZ7
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS16100
gene id: 1038856:BBI15_RS16100
uniprot id: A0A1C7E9Y9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1038856:BBI15 RS03050
gene id: 1038856:BBI15_RS03050
uniprot id: A0A1C7EC60
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1038856:BBI15 RS15470
gene id: 1038856:BBI15_RS15470
uniprot id: A0A1C7EB76
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1038856:BBI15 RS06985
gene id: 1038856:BBI15_RS06985
uniprot id: A0A1C7E597
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1038856:BBI15 RS11900
gene id: 1038856:BBI15_RS11900
uniprot id: A0A1C7E855
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS05060
gene id: 1038856:BBI15_RS05060
uniprot id: A0A1C7E588
names: Similarity
messages: Belongs to the peptidase M29 family.

1038856:BBI15 RS06640
gene id: 1038856:BBI15_RS06640
uniprot id: A0A1C7E5U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1038856:BBI15 RS14655
gene id: 1038856:BBI15_RS14655
uniprot id: A0A1C7EA43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

1038856:BBI15 RS09930
gene id: 1038856:BBI15_RS09930
uniprot id: A0A1C7E7J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1038856:BBI15 RS03980
gene id: 1038856:BBI15_RS03980
uniprot id: A0A1C7ECM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS08750
gene id: 1038856:BBI15_RS08750
uniprot id: A0A1C7E6I9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1038856:BBI15 RS09585
gene id: 1038856:BBI15_RS09585
uniprot id: A0A1C7E7D4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1038856:BBI15 RS15760
gene id: 1038856:BBI15_RS15760
uniprot id: A0A1C7EAN6
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

1038856:BBI15 RS13105
gene id: 1038856:BBI15_RS13105
uniprot id: A0A1C7E9A4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1038856:BBI15 RS11815
gene id: 1038856:BBI15_RS11815
uniprot id: A0A1C7E7P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS10990
gene id: 1038856:BBI15_RS10990
uniprot id: A0A1C7E849
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1038856:BBI15 RS13310
gene id: 1038856:BBI15_RS13310
uniprot id: A0A1C7E9D7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1038856:BBI15 RS11420
gene id: 1038856:BBI15_RS11420
uniprot id: A0A1C7E8D1
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS01070
gene id: 1038856:BBI15_RS01070
uniprot id: A0A1C7EAH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1038856:BBI15 RS05485
gene id: 1038856:BBI15_RS05485
uniprot id: A0A1C7EC94
names: Similarity
messages: Belongs to the universal stress protein A family.

1038856:BBI15 RS00640
gene id: 1038856:BBI15_RS00640
uniprot id: A0A1C7EB43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1038856:BBI15 RS08765
gene id: 1038856:BBI15_RS08765
uniprot id: A0A1C7E651
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS08020
gene id: 1038856:BBI15_RS08020
uniprot id: A0A1C7E6M3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1038856:BBI15 RS05005
gene id: 1038856:BBI15_RS05005
uniprot id: A0A1C7E4D3
names: Similarity
messages: Belongs to the peptidase M29 family.

1038856:BBI15 RS07810
gene id: 1038856:BBI15_RS07810
uniprot id: A0A1C7E6E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS05125
gene id: 1038856:BBI15_RS05125
uniprot id: A0A1C7E5V1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1038856:BBI15 RS04100
gene id: 1038856:BBI15_RS04100
uniprot id: A0A1C7ECC8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1038856:BBI15 RS05515
gene id: 1038856:BBI15_RS05515
uniprot id: A0A1C7E5C6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1038856:BBI15 RS07975
gene id: 1038856:BBI15_RS07975
uniprot id: A0A1C7E6H6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1038856:BBI15 RS04700
gene id: 1038856:BBI15_RS04700
uniprot id: A0A1C7E520
names: Similarity
messages: Belongs to the CdaR family.

1038856:BBI15 RS13725
gene id: 1038856:BBI15_RS13725
uniprot id: A0A1C7E9J7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1038856:BBI15 RS09970
gene id: 1038856:BBI15_RS09970
uniprot id: A0A1C7E6T9
names: Similarity
messages: Belongs to the asp23 family.

1038856:BBI15 RS15680
gene id: 1038856:BBI15_RS15680
uniprot id: A0A1C7EAI8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS00620
gene id: 1038856:BBI15_RS00620
uniprot id: A0A1C7EBX2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1038856:BBI15 RS13450
gene id: 1038856:BBI15_RS13450
uniprot id: A0A1C7E9D8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS16105
gene id: 1038856:BBI15_RS16105
uniprot id: A0A1C7EAU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1038856:BBI15 RS14890
gene id: 1038856:BBI15_RS14890
uniprot id: A0A1C7EAX5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1038856:BBI15 RS06740
gene id: 1038856:BBI15_RS06740
uniprot id: A0A1C7E5Y1
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1038856:BBI15 RS06745
gene id: 1038856:BBI15_RS06745
uniprot id: A0A1C7E5U4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

1038856:BBI15 RS10960
gene id: 1038856:BBI15_RS10960
uniprot id: A0A1C7E813
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1038856:BBI15 RS12705
gene id: 1038856:BBI15_RS12705
uniprot id: A0A1C7E8X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1038856:BBI15 RS08430
gene id: 1038856:BBI15_RS08430
uniprot id: A0A1C7E7G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1038856:BBI15 RS10090
gene id: 1038856:BBI15_RS10090
uniprot id: A0A1C7E8C3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1038856:BBI15 RS09620
gene id: 1038856:BBI15_RS09620
uniprot id: A0A1C7E7F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1038856:BBI15 RS00235
gene id: 1038856:BBI15_RS00235
uniprot id: A0A1C7EAZ2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1038856:BBI15 RS13875
gene id: 1038856:BBI15_RS13875
uniprot id: A0A1C7E9J9
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1038856:BBI15 RS04685
gene id: 1038856:BBI15_RS04685
uniprot id: A0A1C7E4M1
names: Similarity
messages: Belongs to the peptidase S8 family.

1038856:BBI15 RS05755
gene id: 1038856:BBI15_RS05755
uniprot id: A0A1C7ED63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1038856:BBI15 RS15910
gene id: 1038856:BBI15_RS15910
uniprot id: A0A1C7EAL5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1038856:BBI15 RS10810
gene id: 1038856:BBI15_RS10810
uniprot id: A0A1C7E773
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1038856:BBI15 RS08035
gene id: 1038856:BBI15_RS08035
uniprot id: A0A1C7E6K2
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1038856:BBI15 RS03360
gene id: 1038856:BBI15_RS03360
uniprot id: A0A1C7ECG1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS08490
gene id: 1038856:BBI15_RS08490
uniprot id: A0A1C7E6T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1038856:BBI15 RS09780
gene id: 1038856:BBI15_RS09780
uniprot id: A0A1C7E7E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1038856:BBI15 RS00335
gene id: 1038856:BBI15_RS00335
uniprot id: A0A1C7EA35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1038856:BBI15 RS08595
gene id: 1038856:BBI15_RS08595
uniprot id: A0A1C7E6U6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1038856:BBI15 RS02515
gene id: 1038856:BBI15_RS02515
uniprot id: A0A1C7ECX8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1038856:BBI15 RS06520
gene id: 1038856:BBI15_RS06520
uniprot id: A0A1C7E5P1
names: Function
names: Similarity
names: Subunit
messages: Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1038856:BBI15 RS14980
gene id: 1038856:BBI15_RS14980
uniprot id: A0A1C7E9F1
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS14845
gene id: 1038856:BBI15_RS14845
uniprot id: A0A1C7EA14
names: Similarity
messages: Belongs to the peptidase S8 family.

1038856:BBI15 RS07415
gene id: 1038856:BBI15_RS07415
uniprot id: A0A1C7E5H6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS12620
gene id: 1038856:BBI15_RS12620
uniprot id: A0A1C7E871
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1038856:BBI15 RS11415
gene id: 1038856:BBI15_RS11415
uniprot id: A0A1C7E7W3
names: Similarity
messages: Belongs to the CpsD/CapB family.

1038856:BBI15 RS05450
gene id: 1038856:BBI15_RS05450
uniprot id: A0A1C7E5B7
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS00805
gene id: 1038856:BBI15_RS00805
uniprot id: A0A1C7EB42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1038856:BBI15 RS08060
gene id: 1038856:BBI15_RS08060
uniprot id: A0A1C7E7B0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1038856:BBI15 RS03230
gene id: 1038856:BBI15_RS03230
uniprot id: A0A1C7ECE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1038856:BBI15 RS09755
gene id: 1038856:BBI15_RS09755
uniprot id: A0A1C7E6Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1038856:BBI15 RS15565
gene id: 1038856:BBI15_RS15565
uniprot id: A0A1C7EAJ6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1038856:BBI15 RS06705
gene id: 1038856:BBI15_RS06705
uniprot id: A0A1C7ED07
names: Similarity
messages: Belongs to the peptidase S49 family.

1038856:BBI15 RS15690
gene id: 1038856:BBI15_RS15690
uniprot id: A0A1C7EAH5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS16130
gene id: 1038856:BBI15_RS16130
uniprot id: A0A1C7EAP4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1038856:BBI15 RS02470
gene id: 1038856:BBI15_RS02470
uniprot id: A0A1C7EB55
names: Similarity
messages: Belongs to the P(II) protein family.

1038856:BBI15 RS02795
gene id: 1038856:BBI15_RS02795
uniprot id: A0A1C7ED38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1038856:BBI15 RS03695
gene id: 1038856:BBI15_RS03695
uniprot id: A0A1C7ECP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS07605
gene id: 1038856:BBI15_RS07605
uniprot id: A0A1C7E701
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1038856:BBI15 RS13155
gene id: 1038856:BBI15_RS13155
uniprot id: A0A1C7E8H3
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1038856:BBI15 RS07225
gene id: 1038856:BBI15_RS07225
uniprot id: A0A1C7E655
names: Similarity
messages: Belongs to the GSP E family.

1038856:BBI15 RS01920
gene id: 1038856:BBI15_RS01920
uniprot id: A0A1C7ECK8
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1038856:BBI15 RS11215
gene id: 1038856:BBI15_RS11215
uniprot id: A0A1C7E8Y6
names: Cofactor
messages: Can also use Mn(2+) ion.

1038856:BBI15 RS13845
gene id: 1038856:BBI15_RS13845
uniprot id: A0A1C7E9P0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1038856:BBI15 RS07115
gene id: 1038856:BBI15_RS07115
uniprot id: A0A1C7E634
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1038856:BBI15 RS01130
gene id: 1038856:BBI15_RS01130
uniprot id: A0A1C7EBC9
names: Similarity
messages: Belongs to the FlgM family.

1038856:BBI15 RS14915
gene id: 1038856:BBI15_RS14915
uniprot id: A0A1C7EAZ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS08075
gene id: 1038856:BBI15_RS08075
uniprot id: A0A1C7E6N6
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1038856:BBI15 RS07620
gene id: 1038856:BBI15_RS07620
uniprot id: A0A1C7E5Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1038856:BBI15 RS04885
gene id: 1038856:BBI15_RS04885
uniprot id: A0A1C7E4A1
names: Similarity
messages: Belongs to the GARS family.

1038856:BBI15 RS01305
gene id: 1038856:BBI15_RS01305
uniprot id: A0A1C7EBB7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type IV subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P).
messages: Has no RuBP-carboxylation activity.
messages: Homodimer.

1038856:BBI15 RS05985
gene id: 1038856:BBI15_RS05985
uniprot id: A0A1C7E4T7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1038856:BBI15 RS00570
gene id: 1038856:BBI15_RS00570
uniprot id: A0A1C7EBW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1038856:BBI15 RS10185
gene id: 1038856:BBI15_RS10185
uniprot id: A0A1C7E6X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1038856:BBI15 RS11220
gene id: 1038856:BBI15_RS11220
uniprot id: A0A1C7E874
names: Similarity
messages: Belongs to the malate synthase family.

1038856:BBI15 RS11320
gene id: 1038856:BBI15_RS11320
uniprot id: A0A1C7E7G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
messages: Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
messages: Cytoplasm

1038856:BBI15 RS05840
gene id: 1038856:BBI15_RS05840
uniprot id: A0A1C7E5I3
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1038856:BBI15 RS08440
gene id: 1038856:BBI15_RS08440
uniprot id: A0A1C7E6R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1038856:BBI15 RS15295
gene id: 1038856:BBI15_RS15295
uniprot id: A0A1C7EA92
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1038856:BBI15 RS13590
gene id: 1038856:BBI15_RS13590
uniprot id: A0A1C7E9I8
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1038856:BBI15 RS10160
gene id: 1038856:BBI15_RS10160
uniprot id: A0A1C7E7L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1038856:BBI15 RS15630
gene id: 1038856:BBI15_RS15630
uniprot id: A0A1C7EBB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1038856:BBI15 RS06730
gene id: 1038856:BBI15_RS06730
uniprot id: A0A1C7E535
names: Similarity
messages: Belongs to the YjdM family.

1038856:BBI15 RS09980
gene id: 1038856:BBI15_RS09980
uniprot id: A0A1C7E7K1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1038856:BBI15 RS00815
gene id: 1038856:BBI15_RS00815
uniprot id: A0A1C7EAN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1038856:BBI15 RS09185
gene id: 1038856:BBI15_RS09185
uniprot id: A0A1C7E733
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1038856:BBI15 RS02600
gene id: 1038856:BBI15_RS02600
uniprot id: A0A1C7ECX1
names: Similarity
messages: Belongs to the UPF0312 family.

1038856:BBI15 RS03010
gene id: 1038856:BBI15_RS03010
uniprot id: A0A1C7ECB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1038856:BBI15 RS08475
gene id: 1038856:BBI15_RS08475
uniprot id: A0A1C7E6S9
names: Similarity
messages: Belongs to the HesB/IscA family.

1038856:BBI15 RS01175
gene id: 1038856:BBI15_RS01175
uniprot id: A0A1C7EAJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1038856:BBI15 RS12455
gene id: 1038856:BBI15_RS12455
uniprot id: A0A1C7E840
names: Similarity
messages: Belongs to the ThiD family.

1038856:BBI15 RS02430
gene id: 1038856:BBI15_RS02430
uniprot id: A0A1C7EC07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1038856:BBI15 RS03700
gene id: 1038856:BBI15_RS03700
uniprot id: A0A1C7EDI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS12020
gene id: 1038856:BBI15_RS12020
uniprot id: A0A1C7E7V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS14530
gene id: 1038856:BBI15_RS14530
uniprot id: A0A1C7EA18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1038856:BBI15 RS07765
gene id: 1038856:BBI15_RS07765
uniprot id: A0A1C7E6F4
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1038856:BBI15 RS11115
gene id: 1038856:BBI15_RS11115
uniprot id: A0A1C7E842
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1038856:BBI15 RS01140
gene id: 1038856:BBI15_RS01140
uniprot id: A0A1C7EC44
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1038856:BBI15 RS09760
gene id: 1038856:BBI15_RS09760
uniprot id: A0A1C7E7I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1038856:BBI15 RS12730
gene id: 1038856:BBI15_RS12730
uniprot id: A0A1C7E868
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1038856:BBI15 RS07995
gene id: 1038856:BBI15_RS07995
uniprot id: A0A1C7E662
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box).
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1038856:BBI15 RS01330
gene id: 1038856:BBI15_RS01330
uniprot id: A0A1C7EAM4
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS07430
gene id: 1038856:BBI15_RS07430
uniprot id: A0A1C7E6A8
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1038856:BBI15 RS15955
gene id: 1038856:BBI15_RS15955
uniprot id: A0A1C7EBH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS00530
gene id: 1038856:BBI15_RS00530
uniprot id: A0A1C7EB33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1038856:BBI15 RS08705
gene id: 1038856:BBI15_RS08705
uniprot id: A0A1C7E643
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1038856:BBI15 RS03735
gene id: 1038856:BBI15_RS03735
uniprot id: A0A1C7EBU0
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS04830
gene id: 1038856:BBI15_RS04830
uniprot id: A0A1C7E5N3
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1038856:BBI15 RS10755
gene id: 1038856:BBI15_RS10755
uniprot id: A0A1C7E763
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1038856:BBI15 RS03015
gene id: 1038856:BBI15_RS03015
uniprot id: A0A1C7ED71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1038856:BBI15 RS01780
gene id: 1038856:BBI15_RS01780
uniprot id: A0A1C7EBP6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1038856:BBI15 RS06140
gene id: 1038856:BBI15_RS06140
uniprot id: A0A1C7E5I7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1038856:BBI15 RS02790
gene id: 1038856:BBI15_RS02790
uniprot id: A0A1C7EC82
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS11370
gene id: 1038856:BBI15_RS11370
uniprot id: A0A1C7E7H3
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1038856:BBI15 RS07985
gene id: 1038856:BBI15_RS07985
uniprot id: A0A1C7E6J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1038856:BBI15 RS09155
gene id: 1038856:BBI15_RS09155
uniprot id: A0A1C7E6E7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1038856:BBI15 RS03670
gene id: 1038856:BBI15_RS03670
uniprot id: A0A1C7ECN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1038856:BBI15 RS02985
gene id: 1038856:BBI15_RS02985
uniprot id: A0A1C7ECA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1038856:BBI15 RS03590
gene id: 1038856:BBI15_RS03590
uniprot id: A0A1C7EDG4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS05470
gene id: 1038856:BBI15_RS05470
uniprot id: A0A1C7E5C7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cyclase 1 superfamily. KynB family.
messages: Binds 2 zinc ions per subunit.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
messages: Homodimer.

1038856:BBI15 RS03290
gene id: 1038856:BBI15_RS03290
uniprot id: A0A1C7EDD2
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS13540
gene id: 1038856:BBI15_RS13540
uniprot id: A0A1C7E8L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1038856:BBI15 RS10710
gene id: 1038856:BBI15_RS10710
uniprot id: A0A1C7E772
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1038856:BBI15 RS10010
gene id: 1038856:BBI15_RS10010
uniprot id: A0A1C7E8D2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1038856:BBI15 RS13965
gene id: 1038856:BBI15_RS13965
uniprot id: A0A1C7E9N3
names: Subcellular Location Annotation
messages: Cytoplasm

1038856:BBI15 RS02620
gene id: 1038856:BBI15_RS02620
uniprot id: A0A1C7EBL5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1038856:BBI15 RS01965
gene id: 1038856:BBI15_RS01965
uniprot id: A0A1C7EB95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1038856:BBI15 RS00600
gene id: 1038856:BBI15_RS00600
uniprot id: A0A1C7EB00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1038856:BBI15 RS01105
gene id: 1038856:BBI15_RS01105
uniprot id: A0A1C7EBD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1038856:BBI15 RS13075
gene id: 1038856:BBI15_RS13075
uniprot id: A0A1C7E950
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS01880
gene id: 1038856:BBI15_RS01880
uniprot id: A0A1C7EBR3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1038856:BBI15 RS00365
gene id: 1038856:BBI15_RS00365
uniprot id: A0A1C7EAW7
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1038856:BBI15 RS01295
gene id: 1038856:BBI15_RS01295
uniprot id: A0A1C7EC78
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

1038856:BBI15 RS12315
gene id: 1038856:BBI15_RS12315
uniprot id: A0A1C7E9I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS07045
gene id: 1038856:BBI15_RS07045
uniprot id: A0A1C7E601
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1038856:BBI15 RS06675
gene id: 1038856:BBI15_RS06675
uniprot id: A0A1C7E537
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1038856:BBI15 RS09955
gene id: 1038856:BBI15_RS09955
uniprot id: A0A1C7E7M1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1038856:BBI15 RS05025
gene id: 1038856:BBI15_RS05025
uniprot id: A0A1C7E552
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1038856:BBI15 RS05720
gene id: 1038856:BBI15_RS05720
uniprot id: A0A1C7E637
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1038856:BBI15 RS10500
gene id: 1038856:BBI15_RS10500
uniprot id: A0A1C7E734
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS07685
gene id: 1038856:BBI15_RS07685
uniprot id: A0A1C7E736
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1038856:BBI15 RS00630
gene id: 1038856:BBI15_RS00630
uniprot id: A0A1C7EAA2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS07895
gene id: 1038856:BBI15_RS07895
uniprot id: A0A1C7E6K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1038856:BBI15 RS06395
gene id: 1038856:BBI15_RS06395
uniprot id: A0A1C7E4Y4
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS10530
gene id: 1038856:BBI15_RS10530
uniprot id: A0A1C7E7E9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS06425
gene id: 1038856:BBI15_RS06425
uniprot id: A0A1C7E5D6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1038856:BBI15 RS02615
gene id: 1038856:BBI15_RS02615
uniprot id: A0A1C7EBZ6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1038856:BBI15 RS07275
gene id: 1038856:BBI15_RS07275
uniprot id: A0A1C7EE52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1038856:BBI15 RS06180
gene id: 1038856:BBI15_RS06180
uniprot id: A0A1C7ED70
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS08095
gene id: 1038856:BBI15_RS08095
uniprot id: A0A1C7E6L2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1038856:BBI15 RS11260
gene id: 1038856:BBI15_RS11260
uniprot id: A0A1C7E7H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS04000
gene id: 1038856:BBI15_RS04000
uniprot id: A0A1C7EDR7
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1038856:BBI15 RS07035
gene id: 1038856:BBI15_RS07035
uniprot id: A0A1C7E5B3
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1038856:BBI15 RS05930
gene id: 1038856:BBI15_RS05930
uniprot id: A0A1C7E4R2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1038856:BBI15 RS06550
gene id: 1038856:BBI15_RS06550
uniprot id: A0A1C7E5V0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1038856:BBI15 RS13550
gene id: 1038856:BBI15_RS13550
uniprot id: A0A1C7E9I3
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS00245
gene id: 1038856:BBI15_RS00245
uniprot id: A0A1C7EBQ6
names: Similarity
messages: Belongs to the RutC family.

1038856:BBI15 RS07065
gene id: 1038856:BBI15_RS07065
uniprot id: A0A1C7E5N5
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1038856:BBI15 RS09415
gene id: 1038856:BBI15_RS09415
uniprot id: A0A1C7E818
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS09825
gene id: 1038856:BBI15_RS09825
uniprot id: A0A1C7E7F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1038856:BBI15 RS13125
gene id: 1038856:BBI15_RS13125
uniprot id: A0A1C7E966
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1038856:BBI15 RS04655
gene id: 1038856:BBI15_RS04655
uniprot id: A0A1C7E469
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS02155
gene id: 1038856:BBI15_RS02155
uniprot id: A0A1C7EBW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1038856:BBI15 RS02090
gene id: 1038856:BBI15_RS02090
uniprot id: A0A1C7EB10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1038856:BBI15 RS16755
gene id: 1038856:BBI15_RS16755
uniprot id: A0A1C7E5R9
names: Function
messages: Required for transformation and DNA binding.

1038856:BBI15 RS07800
gene id: 1038856:BBI15_RS07800
uniprot id: A0A1C7E5P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1038856:BBI15 RS01640
gene id: 1038856:BBI15_RS01640
uniprot id: A0A1C7EAR6
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1038856:BBI15 RS08840
gene id: 1038856:BBI15_RS08840
uniprot id: A0A1C7E6Y8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS01985
gene id: 1038856:BBI15_RS01985
uniprot id: A0A1C7EAZ1
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1038856:BBI15 RS07730
gene id: 1038856:BBI15_RS07730
uniprot id: A0A1C7E6H1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1038856:BBI15 RS07120
gene id: 1038856:BBI15_RS07120
uniprot id: A0A1C7E612
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1038856:BBI15 RS15310
gene id: 1038856:BBI15_RS15310
uniprot id: A0A1C7EB64
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

1038856:BBI15 RS10305
gene id: 1038856:BBI15_RS10305
uniprot id: A0A1C7E7Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1038856:BBI15 RS07380
gene id: 1038856:BBI15_RS07380
uniprot id: A0A1C7E664
names: Similarity
messages: Belongs to the RecJ family.

1038856:BBI15 RS10910
gene id: 1038856:BBI15_RS10910
uniprot id: A0A1C7E7M3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

1038856:BBI15 RS16095
gene id: 1038856:BBI15_RS16095
uniprot id: A0A1C7E9W2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1038856:BBI15 RS15965
gene id: 1038856:BBI15_RS15965
uniprot id: A0A1C7EAK8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1038856:BBI15 RS01835
gene id: 1038856:BBI15_RS01835
uniprot id: A0A1C7EBP3
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS13245
gene id: 1038856:BBI15_RS13245
uniprot id: A0A1C7E983
names: Similarity
messages: Belongs to the EamA transporter family.

1038856:BBI15 RS07795
gene id: 1038856:BBI15_RS07795
uniprot id: A0A1C7E5Q0
names: Similarity
messages: Belongs to the transpeptidase family.

1038856:BBI15 RS10050
gene id: 1038856:BBI15_RS10050
uniprot id: A0A1C7E7I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS01015
gene id: 1038856:BBI15_RS01015
uniprot id: A0A1C7EAG0
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS08495
gene id: 1038856:BBI15_RS08495
uniprot id: A0A1C7E6R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1038856:BBI15 RS13895
gene id: 1038856:BBI15_RS13895
uniprot id: A0A1C7EAF9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1038856:BBI15 RS07755
gene id: 1038856:BBI15_RS07755
uniprot id: A0A1C7E6D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS09710
gene id: 1038856:BBI15_RS09710
uniprot id: A0A1C7E7H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1038856:BBI15 RS12050
gene id: 1038856:BBI15_RS12050
uniprot id: A0A1C7E886
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1038856:BBI15 RS14280
gene id: 1038856:BBI15_RS14280
uniprot id: A0A1C7E9T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS13485
gene id: 1038856:BBI15_RS13485
uniprot id: A0A1C7EA82
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1038856:BBI15 RS10465
gene id: 1038856:BBI15_RS10465
uniprot id: A0A1C7E7S5
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1038856:BBI15 RS10145
gene id: 1038856:BBI15_RS10145
uniprot id: A0A1C7E7M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1038856:BBI15 RS15590
gene id: 1038856:BBI15_RS15590
uniprot id: A0A1C7EA08
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS15560
gene id: 1038856:BBI15_RS15560
uniprot id: A0A1C7E9P7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1038856:BBI15 RS03775
gene id: 1038856:BBI15_RS03775
uniprot id: A0A1C7EC67
names: Similarity
messages: Belongs to the cytochrome P450 family.

1038856:BBI15 RS01220
gene id: 1038856:BBI15_RS01220
uniprot id: A0A1C7EC89
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1038856:BBI15 RS01585
gene id: 1038856:BBI15_RS01585
uniprot id: A0A1C7EAQ7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1038856:BBI15 RS10420
gene id: 1038856:BBI15_RS10420
uniprot id: A0A1C7E7R1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1038856:BBI15 RS06485
gene id: 1038856:BBI15_RS06485
uniprot id: A0A1C7E5M8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1038856:BBI15 RS01145
gene id: 1038856:BBI15_RS01145
uniprot id: A0A1C7EB87
names: Similarity
messages: Belongs to the bacterial flagellin family.

1038856:BBI15 RS03250
gene id: 1038856:BBI15_RS03250
uniprot id: A0A1C7EBN3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1038856:BBI15 RS05215
gene id: 1038856:BBI15_RS05215
uniprot id: A0A1C7E4H7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1038856:BBI15 RS10130
gene id: 1038856:BBI15_RS10130
uniprot id: A0A1C7E6T6
names: Subcellular Location Annotation
messages: Cytoplasm

1038856:BBI15 RS07700
gene id: 1038856:BBI15_RS07700
uniprot id: A0A1C7E6G0
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1038856:BBI15 RS00755
gene id: 1038856:BBI15_RS00755
uniprot id: A0A1C7EB32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1038856:BBI15 RS14140
gene id: 1038856:BBI15_RS14140
uniprot id: A0A1C7E9P2
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1038856:BBI15 RS05700
gene id: 1038856:BBI15_RS05700
uniprot id: A0A1C7E4L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1038856:BBI15 RS05600
gene id: 1038856:BBI15_RS05600
uniprot id: A0A1C7E4M4
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS14395
gene id: 1038856:BBI15_RS14395
uniprot id: A0A1C7EAN5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1038856:BBI15 RS07490
gene id: 1038856:BBI15_RS07490
uniprot id: A0A1C7E6C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1038856:BBI15 RS01905
gene id: 1038856:BBI15_RS01905
uniprot id: A0A1C7EB84
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1038856:BBI15 RS06700
gene id: 1038856:BBI15_RS06700
uniprot id: A0A1C7ED21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1038856:BBI15 RS01535
gene id: 1038856:BBI15_RS01535
uniprot id: A0A1C7EAP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS03215
gene id: 1038856:BBI15_RS03215
uniprot id: A0A1C7EC91
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS00910
gene id: 1038856:BBI15_RS00910
uniprot id: A0A1C7ECL3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1038856:BBI15 RS07145
gene id: 1038856:BBI15_RS07145
uniprot id: A0A1C7E5D3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1038856:BBI15 RS10790
gene id: 1038856:BBI15_RS10790
uniprot id: A0A1C7E7K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS14290
gene id: 1038856:BBI15_RS14290
uniprot id: A0A1C7EAK9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1038856:BBI15 RS12815
gene id: 1038856:BBI15_RS12815
uniprot id: A0A1C7E8M1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1038856:BBI15 RS02580
gene id: 1038856:BBI15_RS02580
uniprot id: A0A1C7EB75
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

1038856:BBI15 RS11150
gene id: 1038856:BBI15_RS11150
uniprot id: A0A1C7E881
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1038856:BBI15 RS09240
gene id: 1038856:BBI15_RS09240
uniprot id: A0A1C7E6S0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1038856:BBI15 RS12720
gene id: 1038856:BBI15_RS12720
uniprot id: A0A1C7E924
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1038856:BBI15 RS07470
gene id: 1038856:BBI15_RS07470
uniprot id: A0A1C7E6Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1038856:BBI15 RS12100
gene id: 1038856:BBI15_RS12100
uniprot id: A0A1C7E895
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1038856:BBI15 RS09435
gene id: 1038856:BBI15_RS09435
uniprot id: A0A1C7E7A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1038856:BBI15 RS15460
gene id: 1038856:BBI15_RS15460
uniprot id: A0A1C7ECJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1038856:BBI15 RS08085
gene id: 1038856:BBI15_RS08085
uniprot id: A0A1C7E7A0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1038856:BBI15 RS10035
gene id: 1038856:BBI15_RS10035
uniprot id: A0A1C7E8B5
names: Similarity
messages: Belongs to the RemA family.

1038856:BBI15 RS16760
gene id: 1038856:BBI15_RS16760
uniprot id: A0A1C7E8Y9
names: Similarity
messages: Belongs to the peptidase S8 family.

1038856:BBI15 RS08390
gene id: 1038856:BBI15_RS08390
uniprot id: A0A1C7E6Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1038856:BBI15 RS01080
gene id: 1038856:BBI15_RS01080
uniprot id: A0A1C7EBB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1038856:BBI15 RS15370
gene id: 1038856:BBI15_RS15370
uniprot id: A0A1C7E9I5
names: Similarity
messages: Belongs to the peptidase S51 family.

1038856:BBI15 RS10180
gene id: 1038856:BBI15_RS10180
uniprot id: A0A1C7E6V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

1038856:BBI15 RS05785
gene id: 1038856:BBI15_RS05785
uniprot id: A0A1C7E5H3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1038856:BBI15 RS02540
gene id: 1038856:BBI15_RS02540
uniprot id: A0A1C7EC25
names: Similarity
messages: Belongs to the TrpC family.

1038856:BBI15 RS01625
gene id: 1038856:BBI15_RS01625
uniprot id: A0A1C7EB26
names: Similarity
messages: Belongs to the peptidase S8 family.

1038856:BBI15 RS08825
gene id: 1038856:BBI15_RS08825
uniprot id: A0A1C7E719
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Forms a 24-polypeptide structural core with octahedral symmetry. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1038856:BBI15 RS01550
gene id: 1038856:BBI15_RS01550
uniprot id: A0A1C7EBK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1038856:BBI15 RS03315
gene id: 1038856:BBI15_RS03315
uniprot id: A0A1C7ECH9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1038856:BBI15 RS12820
gene id: 1038856:BBI15_RS12820
uniprot id: A0A1C7E941
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS05135
gene id: 1038856:BBI15_RS05135
uniprot id: A0A1C7E531
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1038856:BBI15 RS13295
gene id: 1038856:BBI15_RS13295
uniprot id: A0A1C7E988
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1038856:BBI15 RS07495
gene id: 1038856:BBI15_RS07495
uniprot id: A0A1C7E684
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1038856:BBI15 RS07090
gene id: 1038856:BBI15_RS07090
uniprot id: A0A1C7E5C3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1038856:BBI15 RS04635
gene id: 1038856:BBI15_RS04635
uniprot id: A0A1C7E4K8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1038856:BBI15 RS06045
gene id: 1038856:BBI15_RS06045
uniprot id: A0A1C7E5P4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1038856:BBI15 RS16120
gene id: 1038856:BBI15_RS16120
uniprot id: A0A1C7EBL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1038856:BBI15 RS13955
gene id: 1038856:BBI15_RS13955
uniprot id: A0A1C7E8X1
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1038856:BBI15 RS14905
gene id: 1038856:BBI15_RS14905
uniprot id: A0A1C7E9N1
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS00735
gene id: 1038856:BBI15_RS00735
uniprot id: A0A1C7EAC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1038856:BBI15 RS07675
gene id: 1038856:BBI15_RS07675
uniprot id: A0A1C7E5Z7
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1038856:BBI15 RS09160
gene id: 1038856:BBI15_RS09160
uniprot id: A0A1C7E780
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1038856:BBI15 RS03720
gene id: 1038856:BBI15_RS03720
uniprot id: A0A1C7EC58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1038856:BBI15 RS01155
gene id: 1038856:BBI15_RS01155
uniprot id: A0A1C7EAT7
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1038856:BBI15 RS00750
gene id: 1038856:BBI15_RS00750
uniprot id: A0A1C7EBY5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1038856:BBI15 RS11975
gene id: 1038856:BBI15_RS11975
uniprot id: A0A1C7E8N8
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS09285
gene id: 1038856:BBI15_RS09285
uniprot id: A0A1C7E7X4
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

1038856:BBI15 RS13265
gene id: 1038856:BBI15_RS13265
uniprot id: A0A1C7E8G9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1038856:BBI15 RS09790
gene id: 1038856:BBI15_RS09790
uniprot id: A0A1C7E7I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1038856:BBI15 RS12555
gene id: 1038856:BBI15_RS12555
uniprot id: A0A1C7E841
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

1038856:BBI15 RS09905
gene id: 1038856:BBI15_RS09905
uniprot id: A0A1C7E8B6
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1038856:BBI15 RS07370
gene id: 1038856:BBI15_RS07370
uniprot id: A0A1C7E6A1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1038856:BBI15 RS00695
gene id: 1038856:BBI15_RS00695
uniprot id: A0A1C7EB50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1038856:BBI15 RS10620
gene id: 1038856:BBI15_RS10620
uniprot id: A0A1C7E7V6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1038856:BBI15 RS09660
gene id: 1038856:BBI15_RS09660
uniprot id: A0A1C7E7E5
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS06525
gene id: 1038856:BBI15_RS06525
uniprot id: A0A1C7ED76
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1038856:BBI15 RS06770
gene id: 1038856:BBI15_RS06770
uniprot id: A0A1C7E5Y7
names: Similarity
messages: Belongs to the UPF0173 family.

1038856:BBI15 RS14880
gene id: 1038856:BBI15_RS14880
uniprot id: A0A1C7EA80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS05615
gene id: 1038856:BBI15_RS05615
uniprot id: A0A1C7E618
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.

1038856:BBI15 RS00785
gene id: 1038856:BBI15_RS00785
uniprot id: A0A1C7EAD0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1038856:BBI15 RS13040
gene id: 1038856:BBI15_RS13040
uniprot id: A0A1C7E8C7
names: Similarity
messages: Belongs to the ThiD family.

1038856:BBI15 RS04510
gene id: 1038856:BBI15_RS04510
uniprot id: A0A1C7ED36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1038856:BBI15 RS05770
gene id: 1038856:BBI15_RS05770
uniprot id: A0A1C7E5B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1038856:BBI15 RS10830
gene id: 1038856:BBI15_RS10830
uniprot id: A0A1C7E8R8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1038856:BBI15 RS06580
gene id: 1038856:BBI15_RS06580
uniprot id: A0A1C7E6G8
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1038856:BBI15 RS06465
gene id: 1038856:BBI15_RS06465
uniprot id: A0A1C7E5T2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1038856:BBI15 RS05085
gene id: 1038856:BBI15_RS05085
uniprot id: A0A1C7E4U8
names: Similarity
messages: Belongs to the UPF0435 family.

1038856:BBI15 RS07445
gene id: 1038856:BBI15_RS07445
uniprot id: A0A1C7E695
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

1038856:BBI15 RS04315
gene id: 1038856:BBI15_RS04315
uniprot id: A0A1C7ED05
names: Similarity
messages: Belongs to the PspA/IM30 family.

1038856:BBI15 RS03125
gene id: 1038856:BBI15_RS03125
uniprot id: A0A1C7ED92
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1038856:BBI15 RS03120
gene id: 1038856:BBI15_RS03120
uniprot id: A0A1C7ECC7
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1038856:BBI15 RS07585
gene id: 1038856:BBI15_RS07585
uniprot id: A0A1C7E5K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1038856:BBI15 RS11360
gene id: 1038856:BBI15_RS11360
uniprot id: A0A1C7E8C0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1038856:BBI15 RS02295
gene id: 1038856:BBI15_RS02295
uniprot id: A0A1C7EBT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1038856:BBI15 RS04500
gene id: 1038856:BBI15_RS04500
uniprot id: A0A1C7EC70
names: Similarity
messages: Belongs to the CapA family.

1038856:BBI15 RS09775
gene id: 1038856:BBI15_RS09775
uniprot id: A0A1C7E7E8
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

1038856:BBI15 RS08905
gene id: 1038856:BBI15_RS08905
uniprot id: A0A1C7E6L9
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1038856:BBI15 RS07680
gene id: 1038856:BBI15_RS07680
uniprot id: A0A1C7E6G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1038856:BBI15 RS10940
gene id: 1038856:BBI15_RS10940
uniprot id: A0A1C7E839
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1038856:BBI15 RS10105
gene id: 1038856:BBI15_RS10105
uniprot id: A0A1C7E7J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1038856:BBI15 RS10965
gene id: 1038856:BBI15_RS10965
uniprot id: A0A1C7E7N3
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1038856:BBI15 RS06380
gene id: 1038856:BBI15_RS06380
uniprot id: A0A1C7E5S4
names: Similarity
messages: Belongs to the isochorismate synthase family.

1038856:BBI15 RS07735
gene id: 1038856:BBI15_RS07735
uniprot id: A0A1C7E747
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1038856:BBI15 RS15405
gene id: 1038856:BBI15_RS15405
uniprot id: A0A1C7EAA7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1038856:BBI15 RS12765
gene id: 1038856:BBI15_RS12765
uniprot id: A0A1C7E8L1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1038856:BBI15 RS01745
gene id: 1038856:BBI15_RS01745
uniprot id: A0A1C7EDK9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1038856:BBI15 RS11625
gene id: 1038856:BBI15_RS11625
uniprot id: A0A1C7E8D9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1038856:BBI15 RS15360
gene id: 1038856:BBI15_RS15360
uniprot id: A0A1C7EAG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1038856:BBI15 RS09525
gene id: 1038856:BBI15_RS09525
uniprot id: A0A1C7E6L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1038856:BBI15 RS09875
gene id: 1038856:BBI15_RS09875
uniprot id: A0A1C7E887
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1038856:BBI15 RS09770
gene id: 1038856:BBI15_RS09770
uniprot id: A0A1C7E867
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1038856:BBI15 RS07530
gene id: 1038856:BBI15_RS07530
uniprot id: A0A1C7E5J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1038856:BBI15 RS10590
gene id: 1038856:BBI15_RS10590
uniprot id: A0A1C7E8P9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1038856:BBI15 RS09630
gene id: 1038856:BBI15_RS09630
uniprot id: A0A1C7E858
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1038856:BBI15 RS15225
gene id: 1038856:BBI15_RS15225
uniprot id: A0A1C7EB35
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS01315
gene id: 1038856:BBI15_RS01315
uniprot id: A0A1C7EBH1
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1038856:BBI15 RS03830
gene id: 1038856:BBI15_RS03830
uniprot id: A0A1C7ECR9
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

1038856:BBI15 RS13745
gene id: 1038856:BBI15_RS13745
uniprot id: A0A1C7ED73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1038856:BBI15 RS03520
gene id: 1038856:BBI15_RS03520
uniprot id: A0A1C7ECL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS00725
gene id: 1038856:BBI15_RS00725
uniprot id: A0A1C7EBZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1038856:BBI15 RS00635
gene id: 1038856:BBI15_RS00635
uniprot id: A0A1C7EB51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1038856:BBI15 RS04970
gene id: 1038856:BBI15_RS04970
uniprot id: A0A1C7E501
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1038856:BBI15 RS07280
gene id: 1038856:BBI15_RS07280
uniprot id: A0A1C7E665
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1038856:BBI15 RS04630
gene id: 1038856:BBI15_RS04630
uniprot id: A0A1C7E4U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1038856:BBI15 RS01825
gene id: 1038856:BBI15_RS01825
uniprot id: A0A1C7EAW2
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1038856:BBI15 RS16205
gene id: 1038856:BBI15_RS16205
uniprot id: A0A1C7EAQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1038856:BBI15 RS01250
gene id: 1038856:BBI15_RS01250
uniprot id: A0A1C7EBA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1038856:BBI15 RS02550
gene id: 1038856:BBI15_RS02550
uniprot id: A0A1C7ECV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1038856:BBI15 RS05865
gene id: 1038856:BBI15_RS05865
uniprot id: A0A1C7E4Q2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1038856:BBI15 RS00660
gene id: 1038856:BBI15_RS00660
uniprot id: A0A1C7EEG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1038856:BBI15 RS06235
gene id: 1038856:BBI15_RS06235
uniprot id: A0A1C7E5R7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1038856:BBI15 RS12985
gene id: 1038856:BBI15_RS12985
uniprot id: A0A1C7E8B8
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1038856:BBI15 RS08255
gene id: 1038856:BBI15_RS08255
uniprot id: A0A1C7E6S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS09290
gene id: 1038856:BBI15_RS09290
uniprot id: A0A1C7ED52
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1038856:BBI15 RS01645
gene id: 1038856:BBI15_RS01645
uniprot id: A0A1C7EAT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1038856:BBI15 RS06170
gene id: 1038856:BBI15_RS06170
uniprot id: A0A1C7E5Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS01470
gene id: 1038856:BBI15_RS01470
uniprot id: A0A1C7EBJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1038856:BBI15 RS00975
gene id: 1038856:BBI15_RS00975
uniprot id: A0A1C7EB91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1038856:BBI15 RS07170
gene id: 1038856:BBI15_RS07170
uniprot id: A0A1C7E646
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1038856:BBI15 RS12970
gene id: 1038856:BBI15_RS12970
uniprot id: A0A1C7E8P5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1038856:BBI15 RS04800
gene id: 1038856:BBI15_RS04800
uniprot id: A0A1C7E4P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS13280
gene id: 1038856:BBI15_RS13280
uniprot id: A0A1C7E9D9
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1038856:BBI15 RS09380
gene id: 1038856:BBI15_RS09380
uniprot id: A0A1C7E7B8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1038856:BBI15 RS02450
gene id: 1038856:BBI15_RS02450
uniprot id: A0A1C7EBI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1038856:BBI15 RS07565
gene id: 1038856:BBI15_RS07565
uniprot id: A0A1C7E691
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1038856:BBI15 RS10955
gene id: 1038856:BBI15_RS10955
uniprot id: A0A1C7E821
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

1038856:BBI15 RS10745
gene id: 1038856:BBI15_RS10745
uniprot id: A0A1C7E816
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

1038856:BBI15 RS08845
gene id: 1038856:BBI15_RS08845
uniprot id: A0A1C7E6X6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS00360
gene id: 1038856:BBI15_RS00360
uniprot id: A0A1C7EAX0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1038856:BBI15 RS10820
gene id: 1038856:BBI15_RS10820
uniprot id: A0A1C7E827
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS05495
gene id: 1038856:BBI15_RS05495
uniprot id: A0A1C7E5E1
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS12725
gene id: 1038856:BBI15_RS12725
uniprot id: A0A1C7E9T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1038856:BBI15 RS08465
gene id: 1038856:BBI15_RS08465
uniprot id: A0A1C7E629
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1038856:BBI15 RS09945
gene id: 1038856:BBI15_RS09945
uniprot id: A0A1C7E7H0
names: Function
names: Similarity
messages: Belongs to the FapR family.
messages: Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.

1038856:BBI15 RS14405
gene id: 1038856:BBI15_RS14405
uniprot id: A0A1C7E9T7
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

1038856:BBI15 RS05175
gene id: 1038856:BBI15_RS05175
uniprot id: A0A1C7E5W1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1038856:BBI15 RS11135
gene id: 1038856:BBI15_RS11135
uniprot id: A0A1C7E8Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1038856:BBI15 RS14715
gene id: 1038856:BBI15_RS14715
uniprot id: A0A1C7EA54
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

1038856:BBI15 RS12170
gene id: 1038856:BBI15_RS12170
uniprot id: A0A1C7E7W6
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1038856:BBI15 RS11555
gene id: 1038856:BBI15_RS11555
uniprot id: A0A1C7E7L5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1038856:BBI15 RS00615
gene id: 1038856:BBI15_RS00615
uniprot id: A0A1C7EB49
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1038856:BBI15 RS10100
gene id: 1038856:BBI15_RS10100
uniprot id: A0A1C7ECI5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1038856:BBI15 RS09570
gene id: 1038856:BBI15_RS09570
uniprot id: A0A1C7E6J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1038856:BBI15 RS09810
gene id: 1038856:BBI15_RS09810
uniprot id: A0A1C7E7J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

1038856:BBI15 RS02570
gene id: 1038856:BBI15_RS02570
uniprot id: A0A1C7EC40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1038856:BBI15 RS05120
gene id: 1038856:BBI15_RS05120
uniprot id: A0A1C7E509
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS07210
gene id: 1038856:BBI15_RS07210
uniprot id: A0A1C7E635
names: Subcellular Location Annotation
messages: Cell membrane

1038856:BBI15 RS05800
gene id: 1038856:BBI15_RS05800
uniprot id: A0A1C7E5I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1038856:BBI15 RS06535
gene id: 1038856:BBI15_RS06535
uniprot id: A0A1C7E5S5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS08975
gene id: 1038856:BBI15_RS08975
uniprot id: A0A1C7E741
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1038856:BBI15 RS05745
gene id: 1038856:BBI15_RS05745
uniprot id: A0A1C7E633
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1038856:BBI15 RS03350
gene id: 1038856:BBI15_RS03350
uniprot id: A0A1C7EBM0
names: Similarity
messages: Belongs to the transpeptidase family.

1038856:BBI15 RS02635
gene id: 1038856:BBI15_RS02635
uniprot id: A0A1C7ED03
names: Similarity
messages: Belongs to the universal stress protein A family.

1038856:BBI15 RS09130
gene id: 1038856:BBI15_RS09130
uniprot id: A0A1C7E6Q2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1038856:BBI15 RS09910
gene id: 1038856:BBI15_RS09910
uniprot id: A0A1C7E6P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1038856:BBI15 RS12800
gene id: 1038856:BBI15_RS12800
uniprot id: A0A1C7E9T3
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1038856:BBI15 RS08745
gene id: 1038856:BBI15_RS08745
uniprot id: A0A1C7E6V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1038856:BBI15 RS08860
gene id: 1038856:BBI15_RS08860
uniprot id: A0A1C7E7S1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1038856:BBI15 RS06230
gene id: 1038856:BBI15_RS06230
uniprot id: A0A1C7E4X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
messages: Catalyzes the interconversion of ornithine to glutamate semialdehyde.
messages: Cytoplasm

1038856:BBI15 RS06125
gene id: 1038856:BBI15_RS06125
uniprot id: A0A1C7E5I5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1038856:BBI15 RS08875
gene id: 1038856:BBI15_RS08875
uniprot id: A0A1C7E6A0
names: Similarity
messages: Belongs to the UPF0346 family.

1038856:BBI15 RS01615
gene id: 1038856:BBI15_RS01615
uniprot id: A0A1C7EBH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1038856:BBI15 RS11825
gene id: 1038856:BBI15_RS11825
uniprot id: A0A1C7E8K5
names: Similarity
messages: Belongs to the ArsC family.

1038856:BBI15 RS15490
gene id: 1038856:BBI15_RS15490
uniprot id: A0A1C7EAI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1038856:BBI15 RS09150
gene id: 1038856:BBI15_RS09150
uniprot id: A0A1C7E6B5
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

1038856:BBI15 RS13515
gene id: 1038856:BBI15_RS13515
uniprot id: A0A1C7E9C9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS04880
gene id: 1038856:BBI15_RS04880
uniprot id: A0A1C7E5N8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1038856:BBI15 RS08030
gene id: 1038856:BBI15_RS08030
uniprot id: A0A1C7E793
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1038856:BBI15 RS10430
gene id: 1038856:BBI15_RS10430
uniprot id: A0A1C7E7W0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1038856:BBI15 RS13260
gene id: 1038856:BBI15_RS13260
uniprot id: A0A1C7EA40
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1038856:BBI15 RS01730
gene id: 1038856:BBI15_RS01730
uniprot id: A0A1C7ECG3
names: Cofactor
messages: Binds 1 FAD per subunit.

1038856:BBI15 RS15055
gene id: 1038856:BBI15_RS15055
uniprot id: A0A1C7EB05
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS00035
gene id: 1038856:BBI15_RS00035
uniprot id: A0A1C7EAU4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1038856:BBI15 RS00180
gene id: 1038856:BBI15_RS00180
uniprot id: A0A1C7EA26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YabA family.
messages: Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.
messages: Involved in initiation control of chromosome replication.

1038856:BBI15 RS14960
gene id: 1038856:BBI15_RS14960
uniprot id: A0A1C7E9P1
names: Similarity
messages: Belongs to the peptidase S66 family.

1038856:BBI15 RS04295
gene id: 1038856:BBI15_RS04295
uniprot id: A0A1C7EDU3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1038856:BBI15 RS00645
gene id: 1038856:BBI15_RS00645
uniprot id: A0A1C7EBV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1038856:BBI15 RS13660
gene id: 1038856:BBI15_RS13660
uniprot id: A0A1C7E8R6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1038856:BBI15 RS14045
gene id: 1038856:BBI15_RS14045
uniprot id: A0A1C7E9S2
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1038856:BBI15 RS15100
gene id: 1038856:BBI15_RS15100
uniprot id: A0A1C7EAB6
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS06410
gene id: 1038856:BBI15_RS06410
uniprot id: A0A1C7E6E2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1038856:BBI15 RS01255
gene id: 1038856:BBI15_RS01255
uniprot id: A0A1C7EBA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1038856:BBI15 RS06075
gene id: 1038856:BBI15_RS06075
uniprot id: A0A1C7E5M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1038856:BBI15 RS11665
gene id: 1038856:BBI15_RS11665
uniprot id: A0A1C7E8E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

1038856:BBI15 RS11055
gene id: 1038856:BBI15_RS11055
uniprot id: A0A1C7E8V8
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1038856:BBI15 RS13240
gene id: 1038856:BBI15_RS13240
uniprot id: A0A1C7E973
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS15485
gene id: 1038856:BBI15_RS15485
uniprot id: A0A1C7E9Y7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS05460
gene id: 1038856:BBI15_RS05460
uniprot id: A0A1C7E562
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1038856:BBI15 RS02185
gene id: 1038856:BBI15_RS02185
uniprot id: A0A1C7ECN3
names: Subcellular Location Annotation
messages: Cytoplasm

1038856:BBI15 RS00905
gene id: 1038856:BBI15_RS00905
uniprot id: A0A1C7EC01
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

1038856:BBI15 RS11035
gene id: 1038856:BBI15_RS11035
uniprot id: A0A1C7E7B2
names: Similarity
messages: Belongs to the IMPACT family.

1038856:BBI15 RS06755
gene id: 1038856:BBI15_RS06755
uniprot id: A0A1C7E5W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1038856:BBI15 RS12645
gene id: 1038856:BBI15_RS12645
uniprot id: A0A1C7E9P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS09505
gene id: 1038856:BBI15_RS09505
uniprot id: A0A1C7E6W7
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1038856:BBI15 RS11785
gene id: 1038856:BBI15_RS11785
uniprot id: A0A1C7E8G6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.
messages: Belongs to the peptidase S24 family.

1038856:BBI15 RS00810
gene id: 1038856:BBI15_RS00810
uniprot id: A0A1C7EB41
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS09540
gene id: 1038856:BBI15_RS09540
uniprot id: A0A1C7E822
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1038856:BBI15 RS04850
gene id: 1038856:BBI15_RS04850
uniprot id: A0A1C7E4V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1038856:BBI15 RS00930
gene id: 1038856:BBI15_RS00930
uniprot id: A0A1C7EAP8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1038856:BBI15 RS04745
gene id: 1038856:BBI15_RS04745
uniprot id: A0A1C7E4W2
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS05405
gene id: 1038856:BBI15_RS05405
uniprot id: A0A1C7E553
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

1038856:BBI15 RS07980
gene id: 1038856:BBI15_RS07980
uniprot id: A0A1C7E778
names: Similarity
messages: Belongs to the TlyA family.

1038856:BBI15 RS06815
gene id: 1038856:BBI15_RS06815
uniprot id: A0A1C7E5K0
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

1038856:BBI15 RS06245
gene id: 1038856:BBI15_RS06245
uniprot id: A0A1C7E6D2
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS06490
gene id: 1038856:BBI15_RS06490
uniprot id: A0A1C7E5E5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS13000
gene id: 1038856:BBI15_RS13000
uniprot id: A0A1C7E955
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the octanoyltransferase LipL family.
messages: Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes.
messages: The reaction proceeds via a thioester-linked acyl-enzyme intermediate.

1038856:BBI15 RS06035
gene id: 1038856:BBI15_RS06035
uniprot id: A0A1C7E4T1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1038856:BBI15 RS15505
gene id: 1038856:BBI15_RS15505
uniprot id: A0A1C7E9N7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1038856:BBI15 RS10005
gene id: 1038856:BBI15_RS10005
uniprot id: A0A1C7E7M7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1038856:BBI15 RS06690
gene id: 1038856:BBI15_RS06690
uniprot id: A0A1C7E6I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1038856:BBI15 RS06095
gene id: 1038856:BBI15_RS06095
uniprot id: A0A1C7E5P2
names: Similarity
messages: Belongs to the UPF0349 family.

1038856:BBI15 RS04730
gene id: 1038856:BBI15_RS04730
uniprot id: A0A1C7E5N2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS02860
gene id: 1038856:BBI15_RS02860
uniprot id: A0A1C7EBC4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1038856:BBI15 RS06800
gene id: 1038856:BBI15_RS06800
uniprot id: A0A1C7E6K8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1038856:BBI15 RS02645
gene id: 1038856:BBI15_RS02645
uniprot id: A0A1C7EBA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1038856:BBI15 RS13190
gene id: 1038856:BBI15_RS13190
uniprot id: A0A1C7E8T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1038856:BBI15 RS14455
gene id: 1038856:BBI15_RS14455
uniprot id: A0A1C7E9W0
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS04555
gene id: 1038856:BBI15_RS04555
uniprot id: A0A1C7EC75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS07630
gene id: 1038856:BBI15_RS07630
uniprot id: A0A1C7E724
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1038856:BBI15 RS00260
gene id: 1038856:BBI15_RS00260
uniprot id: A0A1C7EAF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1038856:BBI15 RS04065
gene id: 1038856:BBI15_RS04065
uniprot id: A0A1C7EC02
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1038856:BBI15 RS07740
gene id: 1038856:BBI15_RS07740
uniprot id: A0A1C7E5P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. CshB subfamily.
messages: Cytoplasm
messages: Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.

1038856:BBI15 RS03825
gene id: 1038856:BBI15_RS03825
uniprot id: A0A1C7EC81
names: Function
names: Similarity
messages: Functions as a fatty acid monooxygenase.
messages: In the N-terminal section; belongs to the cytochrome P450 family.

1038856:BBI15 RS00265
gene id: 1038856:BBI15_RS00265
uniprot id: A0A1C7EAZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1038856:BBI15 RS00655
gene id: 1038856:BBI15_RS00655
uniprot id: A0A1C7EB06
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS03945
gene id: 1038856:BBI15_RS03945
uniprot id: A0A1C7EDQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1038856:BBI15 RS06385
gene id: 1038856:BBI15_RS06385
uniprot id: A0A1C7E6D0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1038856:BBI15 RS09675
gene id: 1038856:BBI15_RS09675
uniprot id: A0A1C7E7B7
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1038856:BBI15 RS13455
gene id: 1038856:BBI15_RS13455
uniprot id: A0A1C7EA53
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1038856:BBI15 RS10445
gene id: 1038856:BBI15_RS10445
uniprot id: A0A1C7E722
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1038856:BBI15 RS04175
gene id: 1038856:BBI15_RS04175
uniprot id: A0A1C7EC43
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1038856:BBI15 RS08045
gene id: 1038856:BBI15_RS08045
uniprot id: A0A1C7E672
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1038856:BBI15 RS15990
gene id: 1038856:BBI15_RS15990
uniprot id: A0A1C7E9X2
names: Subcellular Location Annotation
messages: Cytoplasm

1038856:BBI15 RS04490
gene id: 1038856:BBI15_RS04490
uniprot id: A0A1C7ED32
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS02775
gene id: 1038856:BBI15_RS02775
uniprot id: A0A1C7EC27
names: Subcellular Location Annotation
messages: Cell membrane

1038856:BBI15 RS13110
gene id: 1038856:BBI15_RS13110
uniprot id: A0A1C7E977
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS10210
gene id: 1038856:BBI15_RS10210
uniprot id: A0A1C7E7L8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1038856:BBI15 RS10750
gene id: 1038856:BBI15_RS10750
uniprot id: A0A1C7E8S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein required for efficient degradation of Spx by ClpXP under non-stress conditions. Interaction with Spx stabilizes Spx and exposes the C-terminus of Spx for recognition and proteolysis by ClpXP.
messages: Belongs to the SpxH family.
messages: Cytoplasm
messages: Interacts with Spx.

1038856:BBI15 RS15455
gene id: 1038856:BBI15_RS15455
uniprot id: A0A1C7EAH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1038856:BBI15 RS14260
gene id: 1038856:BBI15_RS14260
uniprot id: A0A1C7E906
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS07285
gene id: 1038856:BBI15_RS07285
uniprot id: A0A1C7E642
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1038856:BBI15 RS00340
gene id: 1038856:BBI15_RS00340
uniprot id: A0A1C7EA56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1038856:BBI15 RS02040
gene id: 1038856:BBI15_RS02040
uniprot id: A0A1C7EBU5
names: Subcellular Location Annotation
messages: Cell membrane

1038856:BBI15 RS03295
gene id: 1038856:BBI15_RS03295
uniprot id: A0A1C7EBK2
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1038856:BBI15 RS10030
gene id: 1038856:BBI15_RS10030
uniprot id: A0A1C7E7K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1038856:BBI15 RS13500
gene id: 1038856:BBI15_RS13500
uniprot id: A0A1C7E9H4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS01245
gene id: 1038856:BBI15_RS01245
uniprot id: A0A1C7EC66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1038856:BBI15 RS08425
gene id: 1038856:BBI15_RS08425
uniprot id: A0A1C7E6R7
names: Similarity
messages: Belongs to the SCO1/2 family.

1038856:BBI15 RS06895
gene id: 1038856:BBI15_RS06895
uniprot id: A0A1C7E5X4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1038856:BBI15 RS06165
gene id: 1038856:BBI15_RS06165
uniprot id: A0A1C7E4W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

1038856:BBI15 RS11955
gene id: 1038856:BBI15_RS11955
uniprot id: A0A1C7E8N5
names: Similarity
messages: Belongs to the thioesterase family.

1038856:BBI15 RS16180
gene id: 1038856:BBI15_RS16180
uniprot id: A0A1C7EAV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.

1038856:BBI15 RS13385
gene id: 1038856:BBI15_RS13385
uniprot id: A0A1C7E9F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1038856:BBI15 RS07140
gene id: 1038856:BBI15_RS07140
uniprot id: A0A1C7E5C9
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS14625
gene id: 1038856:BBI15_RS14625
uniprot id: A0A1C7E9X5
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS05055
gene id: 1038856:BBI15_RS05055
uniprot id: A0A1C7E4E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1038856:BBI15 RS14400
gene id: 1038856:BBI15_RS14400
uniprot id: A0A1C7E9V0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1038856:BBI15 RS03285
gene id: 1038856:BBI15_RS03285
uniprot id: A0A1C7ECG8
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1038856:BBI15 RS07455
gene id: 1038856:BBI15_RS07455
uniprot id: A0A1C7E5V8
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1038856:BBI15 RS13020
gene id: 1038856:BBI15_RS13020
uniprot id: A0A1C7E942
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1038856:BBI15 RS11565
gene id: 1038856:BBI15_RS11565
uniprot id: A0A1C7E8D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1038856:BBI15 RS13370
gene id: 1038856:BBI15_RS13370
uniprot id: A0A1C7EA62
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1038856:BBI15 RS02230
gene id: 1038856:BBI15_RS02230
uniprot id: A0A1C7ECP7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS14650
gene id: 1038856:BBI15_RS14650
uniprot id: A0A1C7E997
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS01410
gene id: 1038856:BBI15_RS01410
uniprot id: A0A1C7EAY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1038856:BBI15 RS00095
gene id: 1038856:BBI15_RS00095
uniprot id: A0A1C7E9Z6
names: Similarity
messages: Belongs to the DCK/DGK family.

1038856:BBI15 RS00590
gene id: 1038856:BBI15_RS00590
uniprot id: A0A1C7EB30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1038856:BBI15 RS14370
gene id: 1038856:BBI15_RS14370
uniprot id: A0A1C7EAN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1038856:BBI15 RS12560
gene id: 1038856:BBI15_RS12560
uniprot id: A0A1C7E861
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1038856:BBI15 RS04310
gene id: 1038856:BBI15_RS04310
uniprot id: A0A1C7ECG7
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS16155
gene id: 1038856:BBI15_RS16155
uniprot id: A0A1C7EDH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1038856:BBI15 RS00350
gene id: 1038856:BBI15_RS00350
uniprot id: A0A1C7EAZ8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1038856:BBI15 RS11620
gene id: 1038856:BBI15_RS11620
uniprot id: A0A1C7E957
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1038856:BBI15 RS04960
gene id: 1038856:BBI15_RS04960
uniprot id: A0A1C7E5R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS13285
gene id: 1038856:BBI15_RS13285
uniprot id: A0A1C7E9A8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1038856:BBI15 RS12565
gene id: 1038856:BBI15_RS12565
uniprot id: A0A1C7E900
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS07400
gene id: 1038856:BBI15_RS07400
uniprot id: A0A1C7E5U9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1038856:BBI15 RS04120
gene id: 1038856:BBI15_RS04120
uniprot id: A0A1C7EC32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1038856:BBI15 RS11390
gene id: 1038856:BBI15_RS11390
uniprot id: A0A1C7E918
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS09705
gene id: 1038856:BBI15_RS09705
uniprot id: A0A1C7E6P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1038856:BBI15 RS13830
gene id: 1038856:BBI15_RS13830
uniprot id: A0A1C7E8S3
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS09210
gene id: 1038856:BBI15_RS09210
uniprot id: A0A1C7E6F6
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS03085
gene id: 1038856:BBI15_RS03085
uniprot id: A0A1C7ECA3
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1038856:BBI15 RS05740
gene id: 1038856:BBI15_RS05740
uniprot id: A0A1C7E5H8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1038856:BBI15 RS10585
gene id: 1038856:BBI15_RS10585
uniprot id: A0A1C7E7Z1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS10905
gene id: 1038856:BBI15_RS10905
uniprot id: A0A1C7E802
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

1038856:BBI15 RS09735
gene id: 1038856:BBI15_RS09735
uniprot id: A0A1C7E707
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1038856:BBI15 RS09960
gene id: 1038856:BBI15_RS09960
uniprot id: A0A1C7E8C5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1038856:BBI15 RS03045
gene id: 1038856:BBI15_RS03045
uniprot id: A0A1C7EC65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1038856:BBI15 RS01465
gene id: 1038856:BBI15_RS01465
uniprot id: A0A1C7EAZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1038856:BBI15 RS16070
gene id: 1038856:BBI15_RS16070
uniprot id: A0A1C7EAP0
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS15000
gene id: 1038856:BBI15_RS15000
uniprot id: A0A1C7EA58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1038856:BBI15 RS15950
gene id: 1038856:BBI15_RS15950
uniprot id: A0A1C7EAP7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS04865
gene id: 1038856:BBI15_RS04865
uniprot id: A0A1C7E4Y1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1038856:BBI15 RS15340
gene id: 1038856:BBI15_RS15340
uniprot id: A0A1C7EB59
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1038856:BBI15 RS04860
gene id: 1038856:BBI15_RS04860
uniprot id: A0A1C7E522
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1038856:BBI15 RS13365
gene id: 1038856:BBI15_RS13365
uniprot id: A0A1C7E9F0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1038856:BBI15 RS00625
gene id: 1038856:BBI15_RS00625
uniprot id: A0A1C7EA78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1038856:BBI15 RS06415
gene id: 1038856:BBI15_RS06415
uniprot id: A0A1C7E5R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1038856:BBI15 RS03020
gene id: 1038856:BBI15_RS03020
uniprot id: A0A1C7EBE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1038856:BBI15 RS09260
gene id: 1038856:BBI15_RS09260
uniprot id: A0A1C7E6G7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1038856:BBI15 RS07950
gene id: 1038856:BBI15_RS07950
uniprot id: A0A1C7ED90
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1038856:BBI15 RS07670
gene id: 1038856:BBI15_RS07670
uniprot id: A0A1C7EE38
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1038856:BBI15 RS05165
gene id: 1038856:BBI15_RS05165
uniprot id: A0A1C7E5A4
names: Similarity
messages: Belongs to the UPF0374 family.

1038856:BBI15 RS10085
gene id: 1038856:BBI15_RS10085
uniprot id: A0A1C7E7L9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS10985
gene id: 1038856:BBI15_RS10985
uniprot id: A0A1C7E7C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1038856:BBI15 RS10580
gene id: 1038856:BBI15_RS10580
uniprot id: A0A1C7E7F7
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS12460
gene id: 1038856:BBI15_RS12460
uniprot id: A0A1C7E8X9
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1038856:BBI15 RS04775
gene id: 1038856:BBI15_RS04775
uniprot id: A0A1C7E538
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1038856:BBI15 RS01225
gene id: 1038856:BBI15_RS01225
uniprot id: A0A1C7EAI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1038856:BBI15 RS00680
gene id: 1038856:BBI15_RS00680
uniprot id: A0A1C7EA88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1038856:BBI15 RS04835
gene id: 1038856:BBI15_RS04835
uniprot id: A0A1C7E493
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1038856:BBI15 RS05670
gene id: 1038856:BBI15_RS05670
uniprot id: A0A1C7E627
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1038856:BBI15 RS05975
gene id: 1038856:BBI15_RS05975
uniprot id: A0A1C7E678
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1038856:BBI15 RS10095
gene id: 1038856:BBI15_RS10095
uniprot id: A0A1C7E7K9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1038856:BBI15 RS07820
gene id: 1038856:BBI15_RS07820
uniprot id: A0A1C7E6G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1038856:BBI15 RS12630
gene id: 1038856:BBI15_RS12630
uniprot id: A0A1C7E8Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS00730
gene id: 1038856:BBI15_RS00730
uniprot id: A0A1C7EA99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1038856:BBI15 RS11145
gene id: 1038856:BBI15_RS11145
uniprot id: A0A1C7E7F3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1038856:BBI15 RS09865
gene id: 1038856:BBI15_RS09865
uniprot id: A0A1C7E7K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1038856:BBI15 RS12780
gene id: 1038856:BBI15_RS12780
uniprot id: A0A1C7E878
names: Similarity
messages: Belongs to the UPF0340 family.

1038856:BBI15 RS09940
gene id: 1038856:BBI15_RS09940
uniprot id: A0A1C7E7H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1038856:BBI15 RS03060
gene id: 1038856:BBI15_RS03060
uniprot id: A0A1C7ECC2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1038856:BBI15 RS05375
gene id: 1038856:BBI15_RS05375
uniprot id: A0A1C7E4I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

1038856:BBI15 RS06660
gene id: 1038856:BBI15_RS06660
uniprot id: A0A1C7E6I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1038856:BBI15 RS05190
gene id: 1038856:BBI15_RS05190
uniprot id: A0A1C7E4W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1038856:BBI15 RS05180
gene id: 1038856:BBI15_RS05180
uniprot id: A0A1C7E586
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1038856:BBI15 RS13890
gene id: 1038856:BBI15_RS13890
uniprot id: A0A1C7E9P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1038856:BBI15 RS09750
gene id: 1038856:BBI15_RS09750
uniprot id: A0A1C7E6M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1038856:BBI15 RS00650
gene id: 1038856:BBI15_RS00650
uniprot id: A0A1C7EB13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1038856:BBI15 RS14300
gene id: 1038856:BBI15_RS14300
uniprot id: A0A1C7E9R7
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1038856:BBI15 RS06810
gene id: 1038856:BBI15_RS06810
uniprot id: A0A1C7E5V3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS13905
gene id: 1038856:BBI15_RS13905
uniprot id: A0A1C7E8W3
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1038856:BBI15 RS00255
gene id: 1038856:BBI15_RS00255
uniprot id: A0A1C7EAU7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1038856:BBI15 RS01890
gene id: 1038856:BBI15_RS01890
uniprot id: A0A1C7ECJ1
names: Similarity
messages: Belongs to the UPF0398 family.

1038856:BBI15 RS13390
gene id: 1038856:BBI15_RS13390
uniprot id: A0A1C7E9C8
names: Similarity
messages: Belongs to the peptidase M20A family.

1038856:BBI15 RS03410
gene id: 1038856:BBI15_RS03410
uniprot id: A0A1C7ECH1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1038856:BBI15 RS03145
gene id: 1038856:BBI15_RS03145
uniprot id: A0A1C7EBJ6
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS15230
gene id: 1038856:BBI15_RS15230
uniprot id: A0A1C7EAA0
names: Similarity
messages: Belongs to the peptidase S11 family.

1038856:BBI15 RS09105
gene id: 1038856:BBI15_RS09105
uniprot id: A0A1C7E769
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

1038856:BBI15 RS09490
gene id: 1038856:BBI15_RS09490
uniprot id: A0A1C7E812
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1038856:BBI15 RS01515
gene id: 1038856:BBI15_RS01515
uniprot id: A0A1C7EB07
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1038856:BBI15 RS04770
gene id: 1038856:BBI15_RS04770
uniprot id: A0A1C7E494
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1038856:BBI15 RS06835
gene id: 1038856:BBI15_RS06835
uniprot id: A0A1C7E565
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1038856:BBI15 RS06205
gene id: 1038856:BBI15_RS06205
uniprot id: A0A1C7E5J8
names: Subcellular Location Annotation
messages: Membrane

1038856:BBI15 RS15935
gene id: 1038856:BBI15_RS15935
uniprot id: A0A1C7E9T6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1038856:BBI15 RS12740
gene id: 1038856:BBI15_RS12740
uniprot id: A0A1C7E934
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1038856:BBI15 RS06975
gene id: 1038856:BBI15_RS06975
uniprot id: A0A1C7E6P2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.