1031564:CINS RS00810
gene id: 1031564:CINS_RS00810
uniprot id: A0A0A8GZS8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS04665
gene id: 1031564:CINS_RS04665
uniprot id: A0A0A8H2K9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1031564:CINS RS00855
gene id: 1031564:CINS_RS00855
uniprot id: A0A0A8GZI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1031564:CINS RS00750
gene id: 1031564:CINS_RS00750
uniprot id: A0A0A8H046
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1031564:CINS RS00465
gene id: 1031564:CINS_RS00465
uniprot id: A0A0A8GZL8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1031564:CINS RS03815
gene id: 1031564:CINS_RS03815
uniprot id: A0A0A8H0M6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1031564:CINS RS00310
gene id: 1031564:CINS_RS00310
uniprot id: A0A0A8GZX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1031564:CINS RS05565
gene id: 1031564:CINS_RS05565
uniprot id: A0A0A8H332
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1031564:CINS RS05240
gene id: 1031564:CINS_RS05240
uniprot id: A0A0A8H2Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1031564:CINS RS05580
gene id: 1031564:CINS_RS05580
uniprot id: A0A0A8H1S3
names: Similarity
messages: Belongs to the XseB family.

1031564:CINS RS06850
gene id: 1031564:CINS_RS06850
uniprot id: A0A0A8H2W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1031564:CINS RS02905
gene id: 1031564:CINS_RS02905
uniprot id: A0A0A8H3V4
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS03300
gene id: 1031564:CINS_RS03300
uniprot id: A0A0A8H137
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1031564:CINS RS00240
gene id: 1031564:CINS_RS00240
uniprot id: A0A0A8GYT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

1031564:CINS RS07185
gene id: 1031564:CINS_RS07185
uniprot id: A0A0A8H2S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1031564:CINS RS04405
gene id: 1031564:CINS_RS04405
uniprot id: A0A0A8H4K6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1031564:CINS RS06735
gene id: 1031564:CINS_RS06735
uniprot id: A0A0A8H5V2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS05290
gene id: 1031564:CINS_RS05290
uniprot id: A0A0A8H2Z2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1031564:CINS RS05205
gene id: 1031564:CINS_RS05205
uniprot id: A0A0A8H1L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1031564:CINS RS05520
gene id: 1031564:CINS_RS05520
uniprot id: A0A0A8H1W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1031564:CINS RS03535
gene id: 1031564:CINS_RS03535
uniprot id: A0A0A8H452
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS04425
gene id: 1031564:CINS_RS04425
uniprot id: A0A0A8H0Z4
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS07080
gene id: 1031564:CINS_RS07080
uniprot id: A0A0A8H2Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1031564:CINS RS00145
gene id: 1031564:CINS_RS00145
uniprot id: A0A0A8GZ80
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1031564:CINS RS04895
gene id: 1031564:CINS_RS04895
uniprot id: A0A0A8H1W0
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1031564:CINS RS05585
gene id: 1031564:CINS_RS05585
uniprot id: A0A0A8H5B7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1031564:CINS RS07200
gene id: 1031564:CINS_RS07200
uniprot id: A0A0A8H656
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1031564:CINS RS05470
gene id: 1031564:CINS_RS05470
uniprot id: A0A0A8H1V5
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS05540
gene id: 1031564:CINS_RS05540
uniprot id: A0A0A8H326
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Homodimer.

1031564:CINS RS02695
gene id: 1031564:CINS_RS02695
uniprot id: A0A0A8H0U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1031564:CINS RS07470
gene id: 1031564:CINS_RS07470
uniprot id: A0A0A8H6B6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1031564:CINS RS03885
gene id: 1031564:CINS_RS03885
uniprot id: A0A0A8H126
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1031564:CINS RS01390
gene id: 1031564:CINS_RS01390
uniprot id: A0A0A8GZB4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1031564:CINS RS07230
gene id: 1031564:CINS_RS07230
uniprot id: A0A0A8H409
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS02770
gene id: 1031564:CINS_RS02770
uniprot id: A0A0A8H0V7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1031564:CINS RS03610
gene id: 1031564:CINS_RS03610
uniprot id: A0A0A8H465
names: Similarity
messages: Belongs to the sigma-54 factor family.

1031564:CINS RS02930
gene id: 1031564:CINS_RS02930
uniprot id: A0A0A8H3V6
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS01225
gene id: 1031564:CINS_RS01225
uniprot id: A0A0A8GZP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Dps family.
messages: Cytoplasm

1031564:CINS RS02320
gene id: 1031564:CINS_RS02320
uniprot id: A0A0A8H3J0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1031564:CINS RS07120
gene id: 1031564:CINS_RS07120
uniprot id: A0A0A8H634
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

1031564:CINS RS04805
gene id: 1031564:CINS_RS04805
uniprot id: A0A0A8H166
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1031564:CINS RS04900
gene id: 1031564:CINS_RS04900
uniprot id: A0A0A8H198
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1031564:CINS RS03560
gene id: 1031564:CINS_RS03560
uniprot id: A0A0A8H456
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1031564:CINS RS00375
gene id: 1031564:CINS_RS00375
uniprot id: A0A0A8GYV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1031564:CINS RS00395
gene id: 1031564:CINS_RS00395
uniprot id: A0A0A8GZK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1031564:CINS RS05260
gene id: 1031564:CINS_RS05260
uniprot id: A0A0A8H571
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1031564:CINS RS05045
gene id: 1031564:CINS_RS05045
uniprot id: A0A0A8H217
names: Similarity
messages: Belongs to the AdoMet synthase family.

1031564:CINS RS04655
gene id: 1031564:CINS_RS04655
uniprot id: A0A0A8H136
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1031564:CINS RS05015
gene id: 1031564:CINS_RS05015
uniprot id: A0A0A8H1M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1031564:CINS RS01770
gene id: 1031564:CINS_RS01770
uniprot id: A0A0A8H004
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1031564:CINS RS02170
gene id: 1031564:CINS_RS02170
uniprot id: A0A0A8H091
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1031564:CINS RS04920
gene id: 1031564:CINS_RS04920
uniprot id: A0A0A8H1W8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1031564:CINS RS00260
gene id: 1031564:CINS_RS00260
uniprot id: A0A0A8GZ92
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1031564:CINS RS01885
gene id: 1031564:CINS_RS01885
uniprot id: A0A0A8H3A1
names: Similarity
messages: Belongs to the GSP E family.

1031564:CINS RS02250
gene id: 1031564:CINS_RS02250
uniprot id: A0A0A8H0A0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS03985
gene id: 1031564:CINS_RS03985
uniprot id: A0A0A8H153
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1031564:CINS RS00930
gene id: 1031564:CINS_RS00930
uniprot id: A0A0A8H079
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1031564:CINS RS07215
gene id: 1031564:CINS_RS07215
uniprot id: A0A0A8H329
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS03320
gene id: 1031564:CINS_RS03320
uniprot id: A0A0A8H0T0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

1031564:CINS RS05500
gene id: 1031564:CINS_RS05500
uniprot id: A0A0A8H282
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS03345
gene id: 1031564:CINS_RS03345
uniprot id: A0A0A8H0T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1031564:CINS RS03260
gene id: 1031564:CINS_RS03260
uniprot id: A0A0A8H407
names: Similarity
messages: Belongs to the TlyA family.

1031564:CINS RS07465
gene id: 1031564:CINS_RS07465
uniprot id: A0A0A8H2U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1031564:CINS RS00405
gene id: 1031564:CINS_RS00405
uniprot id: A0A0A8H2I9
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1031564:CINS RS02810
gene id: 1031564:CINS_RS02810
uniprot id: A0A0A8H1K6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1031564:CINS RS04690
gene id: 1031564:CINS_RS04690
uniprot id: A0A0A8H2L4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS05380
gene id: 1031564:CINS_RS05380
uniprot id: A0A0A8H1N9
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1031564:CINS RS07520
gene id: 1031564:CINS_RS07520
uniprot id: A0A0A8H3A5
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS04885
gene id: 1031564:CINS_RS04885
uniprot id: A0A0A8H2R1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

1031564:CINS RS00350
gene id: 1031564:CINS_RS00350
uniprot id: A0A0A8GYU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1031564:CINS RS06140
gene id: 1031564:CINS_RS06140
uniprot id: A0A0A8H3D0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1031564:CINS RS03470
gene id: 1031564:CINS_RS03470
uniprot id: A0A0A8H0V8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1031564:CINS RS03670
gene id: 1031564:CINS_RS03670
uniprot id: A0A0A8H0Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1031564:CINS RS00165
gene id: 1031564:CINS_RS00165
uniprot id: A0A0A8GZU8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1031564:CINS RS01635
gene id: 1031564:CINS_RS01635
uniprot id: A0A0A8GZX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1031564:CINS RS05635
gene id: 1031564:CINS_RS05635
uniprot id: A0A0A8H5C4
names: Similarity
messages: Belongs to the UPF0423 family.

1031564:CINS RS03805
gene id: 1031564:CINS_RS03805
uniprot id: A0A0A8H114
names: Similarity
messages: Belongs to the HypD family.

1031564:CINS RS00105
gene id: 1031564:CINS_RS00105
uniprot id: A0A0A8GZT9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1031564:CINS RS00455
gene id: 1031564:CINS_RS00455
uniprot id: A0A0A8GZZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1031564:CINS RS05265
gene id: 1031564:CINS_RS05265
uniprot id: A0A0A8H2Y9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1031564:CINS RS05745
gene id: 1031564:CINS_RS05745
uniprot id: A0A0A8H1Z5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1031564:CINS RS04840
gene id: 1031564:CINS_RS04840
uniprot id: A0A0A8H2Q0
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1031564:CINS RS02350
gene id: 1031564:CINS_RS02350
uniprot id: A0A0A8H130
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS01760
gene id: 1031564:CINS_RS01760
uniprot id: A0A0A8H0P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1031564:CINS RS06645
gene id: 1031564:CINS_RS06645
uniprot id: A0A0A8H2H1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS03055
gene id: 1031564:CINS_RS03055
uniprot id: A0A0A8H3X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1031564:CINS RS03445
gene id: 1031564:CINS_RS03445
uniprot id: A0A0A8H0V2
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

1031564:CINS RS00355
gene id: 1031564:CINS_RS00355
uniprot id: A0A0A8H2I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1031564:CINS RS03370
gene id: 1031564:CINS_RS03370
uniprot id: A0A0A8H0T9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS02160
gene id: 1031564:CINS_RS02160
uniprot id: A0A0A8H3F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1031564:CINS RS03695
gene id: 1031564:CINS_RS03695
uniprot id: A0A0A8H206
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1031564:CINS RS02005
gene id: 1031564:CINS_RS02005
uniprot id: A0A0A8GZP1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1031564:CINS RS04820
gene id: 1031564:CINS_RS04820
uniprot id: A0A0A8H1G4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1031564:CINS RS04345
gene id: 1031564:CINS_RS04345
uniprot id: A0A0A8H1H4
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS06265
gene id: 1031564:CINS_RS06265
uniprot id: A0A0A8H3F3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1031564:CINS RS04675
gene id: 1031564:CINS_RS04675
uniprot id: A0A0A8H1P9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1031564:CINS RS03340
gene id: 1031564:CINS_RS03340
uniprot id: A0A0A8H1U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1031564:CINS RS06600
gene id: 1031564:CINS_RS06600
uniprot id: A0A0A8H2S2
names: Similarity
messages: Belongs to the peptidase S51 family.

1031564:CINS RS02530
gene id: 1031564:CINS_RS02530
uniprot id: A0A0A8H019
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1031564:CINS RS07395
gene id: 1031564:CINS_RS07395
uniprot id: A0A0A8H695
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1031564:CINS RS06165
gene id: 1031564:CINS_RS06165
uniprot id: A0A0A8H3D4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1031564:CINS RS02345
gene id: 1031564:CINS_RS02345
uniprot id: A0A0A8H3J5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1031564:CINS RS07555
gene id: 1031564:CINS_RS07555
uniprot id: A0A0A8H6D9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1031564:CINS RS02000
gene id: 1031564:CINS_RS02000
uniprot id: A0A0A8H0F6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1031564:CINS RS03475
gene id: 1031564:CINS_RS03475
uniprot id: A0A0A8H159
names: Similarity
messages: Belongs to the YggT family.

1031564:CINS RS04750
gene id: 1031564:CINS_RS04750
uniprot id: A0A0A8H1S0
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

1031564:CINS RS03490
gene id: 1031564:CINS_RS03490
uniprot id: A0A0A8H0W2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS03235
gene id: 1031564:CINS_RS03235
uniprot id: A0A0A8H401
names: Similarity
messages: Belongs to the aspartokinase family.

1031564:CINS RS06580
gene id: 1031564:CINS_RS06580
uniprot id: A0A0A8H2A6
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1031564:CINS RS02260
gene id: 1031564:CINS_RS02260
uniprot id: A0A0A8GZT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS02390
gene id: 1031564:CINS_RS02390
uniprot id: A0A0A8H3K6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1031564:CINS RS01040
gene id: 1031564:CINS_RS01040
uniprot id: A0A0A8GZX2
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1031564:CINS RS05235
gene id: 1031564:CINS_RS05235
uniprot id: A0A0A8H567
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1031564:CINS RS02040
gene id: 1031564:CINS_RS02040
uniprot id: A0A0A8H0V6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

1031564:CINS RS00330
gene id: 1031564:CINS_RS00330
uniprot id: A0A0A8H2H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1031564:CINS RS04370
gene id: 1031564:CINS_RS04370
uniprot id: A0A0A8H1I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

1031564:CINS RS00580
gene id: 1031564:CINS_RS00580
uniprot id: A0A0A8H017
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1031564:CINS RS01125
gene id: 1031564:CINS_RS01125
uniprot id: A0A0A8GZM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1031564:CINS RS00280
gene id: 1031564:CINS_RS00280
uniprot id: A0A0A8GZW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS06290
gene id: 1031564:CINS_RS06290
uniprot id: A0A0A8H3G0
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1031564:CINS RS03175
gene id: 1031564:CINS_RS03175
uniprot id: A0A0A8H0B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1031564:CINS RS03545
gene id: 1031564:CINS_RS03545
uniprot id: A0A0A8H0X3
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1031564:CINS RS00535
gene id: 1031564:CINS_RS00535
uniprot id: A0A0A8GZC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1031564:CINS RS00475
gene id: 1031564:CINS_RS00475
uniprot id: A0A0A8H2K0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1031564:CINS RS05885
gene id: 1031564:CINS_RS05885
uniprot id: A0A0A8H2E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1031564:CINS RS01000
gene id: 1031564:CINS_RS01000
uniprot id: A0A0A8H2S9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1031564:CINS RS05365
gene id: 1031564:CINS_RS05365
uniprot id: A0A0A8H300
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1031564:CINS RS01050
gene id: 1031564:CINS_RS01050
uniprot id: A0A0A8H2T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1031564:CINS RS00865
gene id: 1031564:CINS_RS00865
uniprot id: A0A0A8GZ24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1031564:CINS RS02165
gene id: 1031564:CINS_RS02165
uniprot id: A0A0A8H0Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1031564:CINS RS06535
gene id: 1031564:CINS_RS06535
uniprot id: A0A0A8H5R5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1031564:CINS RS02290
gene id: 1031564:CINS_RS02290
uniprot id: A0A0A8GZU3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1031564:CINS RS06420
gene id: 1031564:CINS_RS06420
uniprot id: A0A0A8H2B9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1031564:CINS RS04410
gene id: 1031564:CINS_RS04410
uniprot id: A0A0A8H2F1
names: Similarity
messages: Belongs to the nitroreductase family.

1031564:CINS RS02135
gene id: 1031564:CINS_RS02135
uniprot id: A0A0A8H3F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1031564:CINS RS00360
gene id: 1031564:CINS_RS00360
uniprot id: A0A0A8GZX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1031564:CINS RS06575
gene id: 1031564:CINS_RS06575
uniprot id: A0A0A8H2R7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1031564:CINS RS02560
gene id: 1031564:CINS_RS02560
uniprot id: A0A0A8H023
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS01705
gene id: 1031564:CINS_RS01705
uniprot id: A0A0A8H0N8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1031564:CINS RS04590
gene id: 1031564:CINS_RS04590
uniprot id: A0A0A8H2J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1031564:CINS RS02240
gene id: 1031564:CINS_RS02240
uniprot id: A0A0A8H3H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1031564:CINS RS07045
gene id: 1031564:CINS_RS07045
uniprot id: A0A0A8H614
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1031564:CINS RS06700
gene id: 1031564:CINS_RS06700
uniprot id: A0A0A8H2T9
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1031564:CINS RS04905
gene id: 1031564:CINS_RS04905
uniprot id: A0A0A8H4Y5
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1031564:CINS RS06930
gene id: 1031564:CINS_RS06930
uniprot id: A0A0A8H2J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1031564:CINS RS00470
gene id: 1031564:CINS_RS00470
uniprot id: A0A0A8GYW7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1031564:CINS RS06520
gene id: 1031564:CINS_RS06520
uniprot id: A0A0A8H2E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1031564:CINS RS00075
gene id: 1031564:CINS_RS00075
uniprot id: A0A0A8H2E5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1031564:CINS RS01235
gene id: 1031564:CINS_RS01235
uniprot id: A0A0A8GZ90
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1031564:CINS RS06250
gene id: 1031564:CINS_RS06250
uniprot id: A0A0A8H2K6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1031564:CINS RS03115
gene id: 1031564:CINS_RS03115
uniprot id: A0A0A8H0Q0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS00380
gene id: 1031564:CINS_RS00380
uniprot id: A0A0A8H2I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1031564:CINS RS06900
gene id: 1031564:CINS_RS06900
uniprot id: A0A0A8H2X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1031564:CINS RS03630
gene id: 1031564:CINS_RS03630
uniprot id: A0A0A8H0J3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1031564:CINS RS00825
gene id: 1031564:CINS_RS00825
uniprot id: A0A0A8H059
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1031564:CINS RS06260
gene id: 1031564:CINS_RS06260
uniprot id: A0A0A8H5L9
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1031564:CINS RS04770
gene id: 1031564:CINS_RS04770
uniprot id: A0A0A8H1F8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

1031564:CINS RS03010
gene id: 1031564:CINS_RS03010
uniprot id: A0A0A8H1N2
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS06870
gene id: 1031564:CINS_RS06870
uniprot id: A0A0A8H2M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1031564:CINS RS00085
gene id: 1031564:CINS_RS00085
uniprot id: A0A0A8GZ71
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1031564:CINS RS04495
gene id: 1031564:CINS_RS04495
uniprot id: A0A0A8H1D0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1031564:CINS RS07090
gene id: 1031564:CINS_RS07090
uniprot id: A0A0A8H2L3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1031564:CINS RS00040
gene id: 1031564:CINS_RS00040
uniprot id: A0A0A8GZF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1031564:CINS RS03030
gene id: 1031564:CINS_RS03030
uniprot id: A0A0A8H3X1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1031564:CINS RS01325
gene id: 1031564:CINS_RS01325
uniprot id: A0A0A8H0F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1031564:CINS RS06860
gene id: 1031564:CINS_RS06860
uniprot id: A0A0A8H5Y2
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS03795
gene id: 1031564:CINS_RS03795
uniprot id: A0A0A8H494
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1031564:CINS RS02755
gene id: 1031564:CINS_RS02755
uniprot id: A0A0A8H3T4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1031564:CINS RS00270
gene id: 1031564:CINS_RS00270
uniprot id: A0A0A8GYT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1031564:CINS RS00530
gene id: 1031564:CINS_RS00530
uniprot id: A0A0A8H008
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS03180
gene id: 1031564:CINS_RS03180
uniprot id: A0A0A8H3Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1031564:CINS RS07135
gene id: 1031564:CINS_RS07135
uniprot id: A0A0A8H2R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1031564:CINS RS03255
gene id: 1031564:CINS_RS03255
uniprot id: A0A0A8H0C6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS06685
gene id: 1031564:CINS_RS06685
uniprot id: A0A0A8H5U0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1031564:CINS RS06170
gene id: 1031564:CINS_RS06170
uniprot id: A0A0A8H269
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1031564:CINS RS05085
gene id: 1031564:CINS_RS05085
uniprot id: A0A0A8H2W9
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.

1031564:CINS RS00660
gene id: 1031564:CINS_RS00660
uniprot id: A0A0A8GYZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1031564:CINS RS02445
gene id: 1031564:CINS_RS02445
uniprot id: A0A0A8H0G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1031564:CINS RS02540
gene id: 1031564:CINS_RS02540
uniprot id: A0A0A8H3Q5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1031564:CINS RS02010
gene id: 1031564:CINS_RS02010
uniprot id: A0A0A8H3C9
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1031564:CINS RS05200
gene id: 1031564:CINS_RS05200
uniprot id: A0A0A8H241
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1031564:CINS RS04475
gene id: 1031564:CINS_RS04475
uniprot id: A0A0A8H1J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1031564:CINS RS03425
gene id: 1031564:CINS_RS03425
uniprot id: A0A0A8H152
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1031564:CINS RS05120
gene id: 1031564:CINS_RS05120
uniprot id: A0A0A8H230
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1031564:CINS RS00500
gene id: 1031564:CINS_RS00500
uniprot id: A0A0A8H2K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1031564:CINS RS07310
gene id: 1031564:CINS_RS07310
uniprot id: A0A0A8H2U9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1031564:CINS RS01060
gene id: 1031564:CINS_RS01060
uniprot id: A0A0A8GZL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1031564:CINS RS00450
gene id: 1031564:CINS_RS00450
uniprot id: A0A0A8H2J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1031564:CINS RS05225
gene id: 1031564:CINS_RS05225
uniprot id: A0A0A8H245
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1031564:CINS RS03160
gene id: 1031564:CINS_RS03160
uniprot id: A0A0A8H1Q7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1031564:CINS RS07070
gene id: 1031564:CINS_RS07070
uniprot id: A0A0A8H621
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1031564:CINS RS01310
gene id: 1031564:CINS_RS01310
uniprot id: A0A0A8H016
names: Similarity
messages: Belongs to the universal stress protein A family.

1031564:CINS RS07615
gene id: 1031564:CINS_RS07615
uniprot id: A0A0A8H191
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1031564:CINS RS00370
gene id: 1031564:CINS_RS00370
uniprot id: A0A0A8GZK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1031564:CINS RS04720
gene id: 1031564:CINS_RS04720
uniprot id: A0A0A8H1F0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS00390
gene id: 1031564:CINS_RS00390
uniprot id: A0A0A8GZA9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1031564:CINS RS06510
gene id: 1031564:CINS_RS06510
uniprot id: A0A0A8H5R1
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1031564:CINS RS07390
gene id: 1031564:CINS_RS07390
uniprot id: A0A0A8H2S4
names: Similarity
messages: Belongs to the UPF0234 family.

1031564:CINS RS02940
gene id: 1031564:CINS_RS02940
uniprot id: A0A0A8H0M5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS04965
gene id: 1031564:CINS_RS04965
uniprot id: A0A0A8H1K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1031564:CINS RS06460
gene id: 1031564:CINS_RS06460
uniprot id: A0A0A8H5Q4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS06635
gene id: 1031564:CINS_RS06635
uniprot id: A0A0A8H5T0
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

1031564:CINS RS07220
gene id: 1031564:CINS_RS07220
uniprot id: A0A0A8H2P1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1031564:CINS RS06105
gene id: 1031564:CINS_RS06105
uniprot id: A0A0A8H5J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1031564:CINS RS04860
gene id: 1031564:CINS_RS04860
uniprot id: A0A0A8H2Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1031564:CINS RS05425
gene id: 1031564:CINS_RS05425
uniprot id: A0A0A8H271
names: Similarity
messages: Belongs to the UPF0763 family.

1031564:CINS RS04585
gene id: 1031564:CINS_RS04585
uniprot id: A0A0A8H4Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1031564:CINS RS07050
gene id: 1031564:CINS_RS07050
uniprot id: A0A0A8H3X0
names: Cofactor
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1031564:CINS RS02985
gene id: 1031564:CINS_RS02985
uniprot id: A0A0A8H1M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1031564:CINS RS05310
gene id: 1031564:CINS_RS05310
uniprot id: A0A0A8H578
names: Similarity
messages: Belongs to the hemerythrin family.

1031564:CINS RS01745
gene id: 1031564:CINS_RS01745
uniprot id: A0A0A8H0A7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1031564:CINS RS04535
gene id: 1031564:CINS_RS04535
uniprot id: A0A0A8H4N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1031564:CINS RS03270
gene id: 1031564:CINS_RS03270
uniprot id: A0A0A8H0S3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS04525
gene id: 1031564:CINS_RS04525
uniprot id: A0A0A8H1L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1031564:CINS RS05860
gene id: 1031564:CINS_RS05860
uniprot id: A0A0A8H2D5
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS04635
gene id: 1031564:CINS_RS04635
uniprot id: A0A0A8H4R7
names: Similarity
messages: Belongs to the peptidase M24B family.

1031564:CINS RS06655
gene id: 1031564:CINS_RS06655
uniprot id: A0A0A8H2C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1031564:CINS RS07530
gene id: 1031564:CINS_RS07530
uniprot id: A0A0A8H6D1
names: Similarity
messages: Belongs to the UxaA family.

1031564:CINS RS01350
gene id: 1031564:CINS_RS01350
uniprot id: A0A0A8H0G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1031564:CINS RS06175
gene id: 1031564:CINS_RS06175
uniprot id: A0A0A8H2J1
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS07415
gene id: 1031564:CINS_RS07415
uniprot id: A0A0A8H2T0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1031564:CINS RS01115
gene id: 1031564:CINS_RS01115
uniprot id: A0A0A8H2U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1031564:CINS RS00860
gene id: 1031564:CINS_RS00860
uniprot id: A0A0A8GZT7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1031564:CINS RS05675
gene id: 1031564:CINS_RS05675
uniprot id: A0A0A8H2A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1031564:CINS RS02765
gene id: 1031564:CINS_RS02765
uniprot id: A0A0A8H0K0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Homodimer.

1031564:CINS RS05555
gene id: 1031564:CINS_RS05555
uniprot id: A0A0A8H1R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1031564:CINS RS03275
gene id: 1031564:CINS_RS03275
uniprot id: A0A0A8H135
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1031564:CINS RS00555
gene id: 1031564:CINS_RS00555
uniprot id: A0A0A8H012
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

1031564:CINS RS04400
gene id: 1031564:CINS_RS04400
uniprot id: A0A0A8H0Z1
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS05070
gene id: 1031564:CINS_RS05070
uniprot id: A0A0A8H221
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1031564:CINS RS01155
gene id: 1031564:CINS_RS01155
uniprot id: A0A0A8GZY8
names: Similarity
messages: Belongs to the LOG family.

1031564:CINS RS07190
gene id: 1031564:CINS_RS07190
uniprot id: A0A0A8H325
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1031564:CINS RS05400
gene id: 1031564:CINS_RS05400
uniprot id: A0A0A8H267
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1031564:CINS RS00920
gene id: 1031564:CINS_RS00920
uniprot id: A0A0A8GZ31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1031564:CINS RS05790
gene id: 1031564:CINS_RS05790
uniprot id: A0A0A8H369
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1031564:CINS RS01960
gene id: 1031564:CINS_RS01960
uniprot id: A0A0A8H3B8
names: Similarity
messages: Belongs to the UPF0751 family.

1031564:CINS RS05680
gene id: 1031564:CINS_RS05680
uniprot id: A0A0A8H1U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1031564:CINS RS00515
gene id: 1031564:CINS_RS00515
uniprot id: A0A0A8GZM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

1031564:CINS RS06090
gene id: 1031564:CINS_RS06090
uniprot id: A0A0A8H254
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1031564:CINS RS00735
gene id: 1031564:CINS_RS00735
uniprot id: A0A0A8GZR4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS02605
gene id: 1031564:CINS_RS02605
uniprot id: A0A0A8H0I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1031564:CINS RS02950
gene id: 1031564:CINS_RS02950
uniprot id: A0A0A8H076
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1031564:CINS RS05890
gene id: 1031564:CINS_RS05890
uniprot id: A0A0A8H1X5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1031564:CINS RS03450
gene id: 1031564:CINS_RS03450
uniprot id: A0A0A8H156
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1031564:CINS RS07155
gene id: 1031564:CINS_RS07155
uniprot id: A0A0A8H3Z3
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

1031564:CINS RS06470
gene id: 1031564:CINS_RS06470
uniprot id: A0A0A8H2D1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1031564:CINS RS05395
gene id: 1031564:CINS_RS05395
uniprot id: A0A0A8H1U3
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1031564:CINS RS05465
gene id: 1031564:CINS_RS05465
uniprot id: A0A0A8H315
names: Similarity
messages: Belongs to the SCO1/2 family.

1031564:CINS RS05850
gene id: 1031564:CINS_RS05850
uniprot id: A0A0A8H378
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1031564:CINS RS00400
gene id: 1031564:CINS_RS00400
uniprot id: A0A0A8GYV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1031564:CINS RS00435
gene id: 1031564:CINS_RS00435
uniprot id: A0A0A8GZY9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1031564:CINS RS02845
gene id: 1031564:CINS_RS02845
uniprot id: A0A0A8H063
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS02795
gene id: 1031564:CINS_RS02795
uniprot id: A0A0A8H0V9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1031564:CINS RS02310
gene id: 1031564:CINS_RS02310
uniprot id: A0A0A8H0L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1031564:CINS RS06375
gene id: 1031564:CINS_RS06375
uniprot id: A0A0A8H2M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1031564:CINS RS07340
gene id: 1031564:CINS_RS07340
uniprot id: A0A0A8H364
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1031564:CINS RS00420
gene id: 1031564:CINS_RS00420
uniprot id: A0A0A8GZL1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1031564:CINS RS05135
gene id: 1031564:CINS_RS05135
uniprot id: A0A0A8H2X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1031564:CINS RS07125
gene id: 1031564:CINS_RS07125
uniprot id: A0A0A8H3Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1031564:CINS RS01070
gene id: 1031564:CINS_RS01070
uniprot id: A0A0A8GZ61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1031564:CINS RS02840
gene id: 1031564:CINS_RS02840
uniprot id: A0A0A8H0W8
names: Similarity
messages: Belongs to the GARS family.

1031564:CINS RS01360
gene id: 1031564:CINS_RS01360
uniprot id: A0A0A8H027
names: Similarity
messages: Belongs to the catalase family.

1031564:CINS RS06070
gene id: 1031564:CINS_RS06070
uniprot id: A0A0A8H2H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1031564:CINS RS03225
gene id: 1031564:CINS_RS03225
uniprot id: A0A0A8H129
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1031564:CINS RS00335
gene id: 1031564:CINS_RS00335
uniprot id: A0A0A8GZX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1031564:CINS RS03420
gene id: 1031564:CINS_RS03420
uniprot id: A0A0A8H0U6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1031564:CINS RS00090
gene id: 1031564:CINS_RS00090
uniprot id: A0A0A8GZG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1031564:CINS RS01215
gene id: 1031564:CINS_RS01215
uniprot id: A0A0A8H2V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1031564:CINS RS03385
gene id: 1031564:CINS_RS03385
uniprot id: A0A0A8H429
names: Similarity
messages: Belongs to the AAA ATPase family.

1031564:CINS RS02670
gene id: 1031564:CINS_RS02670
uniprot id: A0A0A8H0U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1031564:CINS RS06430
gene id: 1031564:CINS_RS06430
uniprot id: A0A0A8H276
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Cell inner membrane
messages: Membrane

1031564:CINS RS00125
gene id: 1031564:CINS_RS00125
uniprot id: A0A0A8GZG6
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1031564:CINS RS05820
gene id: 1031564:CINS_RS05820
uniprot id: A0A0A8H374
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1031564:CINS RS02415
gene id: 1031564:CINS_RS02415
uniprot id: A0A0A8H183
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

1031564:CINS RS04500
gene id: 1031564:CINS_RS04500
uniprot id: A0A0A8H1K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1031564:CINS RS01585
gene id: 1031564:CINS_RS01585
uniprot id: A0A0A8GZX0
names: Similarity
messages: Belongs to the cytochrome P450 family.

1031564:CINS RS01205
gene id: 1031564:CINS_RS01205
uniprot id: A0A0A8GZZ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS06915
gene id: 1031564:CINS_RS06915
uniprot id: A0A0A8H3V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1031564:CINS RS07540
gene id: 1031564:CINS_RS07540
uniprot id: A0A0A8H2Z3
names: Similarity
messages: Belongs to the DapA family.

1031564:CINS RS00010
gene id: 1031564:CINS_RS00010
uniprot id: A0A0A8GZ60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1031564:CINS RS04915
gene id: 1031564:CINS_RS04915
uniprot id: A0A0A8H1I7
names: Similarity
messages: Belongs to the cytochrome c-552 family.

1031564:CINS RS06810
gene id: 1031564:CINS_RS06810
uniprot id: A0A0A8H5X1
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1031564:CINS RS01375
gene id: 1031564:CINS_RS01375
uniprot id: A0A0A8H0G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

1031564:CINS RS05660
gene id: 1031564:CINS_RS05660
uniprot id: A0A0A8H5C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1031564:CINS RS02190
gene id: 1031564:CINS_RS02190
uniprot id: A0A0A8H0Y9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1031564:CINS RS05050
gene id: 1031564:CINS_RS05050
uniprot id: A0A0A8H1J6
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS00320
gene id: 1031564:CINS_RS00320
uniprot id: A0A0A8GZJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1031564:CINS RS00820
gene id: 1031564:CINS_RS00820
uniprot id: A0A0A8H2Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1031564:CINS RS06050
gene id: 1031564:CINS_RS06050
uniprot id: A0A0A8H1Z9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1031564:CINS RS03650
gene id: 1031564:CINS_RS03650
uniprot id: A0A0A8H188
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1031564:CINS RS02860
gene id: 1031564:CINS_RS02860
uniprot id: A0A0A8H0L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1031564:CINS RS00695
gene id: 1031564:CINS_RS00695
uniprot id: A0A0A8H2N1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1031564:CINS RS02120
gene id: 1031564:CINS_RS02120
uniprot id: A0A0A8H078
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1031564:CINS RS05060
gene id: 1031564:CINS_RS05060
uniprot id: A0A0A8H2W4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1031564:CINS RS05765
gene id: 1031564:CINS_RS05765
uniprot id: A0A0A8H365
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS05690
gene id: 1031564:CINS_RS05690
uniprot id: A0A0A8H351
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1031564:CINS RS01405
gene id: 1031564:CINS_RS01405
uniprot id: A0A0A8GZT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1031564:CINS RS00595
gene id: 1031564:CINS_RS00595
uniprot id: A0A0A8GYY9
names: Similarity
messages: Belongs to the Nth/MutY family.

1031564:CINS RS00490
gene id: 1031564:CINS_RS00490
uniprot id: A0A0A8GZM2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1031564:CINS RS05785
gene id: 1031564:CINS_RS05785
uniprot id: A0A0A8H5E8
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS01020
gene id: 1031564:CINS_RS01020
uniprot id: A0A0A8GZ53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1031564:CINS RS06195
gene id: 1031564:CINS_RS06195
uniprot id: A0A0A8H274
names: Similarity
messages: Belongs to the MlaA family.

1031564:CINS RS00630
gene id: 1031564:CINS_RS00630
uniprot id: A0A0A8GYZ3
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS05155
gene id: 1031564:CINS_RS05155
uniprot id: A0A0A8H557
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1031564:CINS RS06695
gene id: 1031564:CINS_RS06695
uniprot id: A0A0A8H2I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1031564:CINS RS04910
gene id: 1031564:CINS_RS04910
uniprot id: A0A0A8H2R8
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

1031564:CINS RS02325
gene id: 1031564:CINS_RS02325
uniprot id: A0A0A8H123
names: Function
names: Similarity
messages: Belongs to the OMP decarboxylase family.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

1031564:CINS RS03770
gene id: 1031564:CINS_RS03770
uniprot id: A0A0A8H219
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1031564:CINS RS01670
gene id: 1031564:CINS_RS01670
uniprot id: A0A0A8GZG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1031564:CINS RS03945
gene id: 1031564:CINS_RS03945
uniprot id: A0A0A8H0P8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1031564:CINS RS03265
gene id: 1031564:CINS_RS03265
uniprot id: A0A0A8H1S6
names: Similarity
messages: Belongs to the ribF family.

1031564:CINS RS05865
gene id: 1031564:CINS_RS05865
uniprot id: A0A0A8H1X2
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS02680
gene id: 1031564:CINS_RS02680
uniprot id: A0A0A8H3S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1031564:CINS RS06905
gene id: 1031564:CINS_RS06905
uniprot id: A0A0A8H2I5
names: Function
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1031564:CINS RS05285
gene id: 1031564:CINS_RS05285
uniprot id: A0A0A8H574
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1031564:CINS RS04930
gene id: 1031564:CINS_RS04930
uniprot id: A0A0A8H4Z1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS06875
gene id: 1031564:CINS_RS06875
uniprot id: A0A0A8H2X1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1031564:CINS RS01950
gene id: 1031564:CINS_RS01950
uniprot id: A0A0A8H0E6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1031564:CINS RS02140
gene id: 1031564:CINS_RS02140
uniprot id: A0A0A8H0X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1031564:CINS RS06570
gene id: 1031564:CINS_RS06570
uniprot id: A0A0A8H2F3
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS00550
gene id: 1031564:CINS_RS00550
uniprot id: A0A0A8H2L2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1031564:CINS RS06760
gene id: 1031564:CINS_RS06760
uniprot id: A0A0A8H5V8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1031564:CINS RS00265
gene id: 1031564:CINS_RS00265
uniprot id: A0A0A8GZI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

1031564:CINS RS00245
gene id: 1031564:CINS_RS00245
uniprot id: A0A0A8H2G6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1031564:CINS RS05835
gene id: 1031564:CINS_RS05835
uniprot id: A0A0A8H2D2
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS00160
gene id: 1031564:CINS_RS00160
uniprot id: A0A0A8H2F5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1031564:CINS RS05185
gene id: 1031564:CINS_RS05185
uniprot id: A0A0A8H560
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1031564:CINS RS05720
gene id: 1031564:CINS_RS05720
uniprot id: A0A0A8H1Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1031564:CINS RS07085
gene id: 1031564:CINS_RS07085
uniprot id: A0A0A8H302
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1031564:CINS RS05250
gene id: 1031564:CINS_RS05250
uniprot id: A0A0A8H247
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1031564:CINS RS01410
gene id: 1031564:CINS_RS01410
uniprot id: A0A0A8H040
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1031564:CINS RS02520
gene id: 1031564:CINS_RS02520
uniprot id: A0A0A8H0H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1031564:CINS RS04550
gene id: 1031564:CINS_RS04550
uniprot id: A0A0A8H1L7
names: Similarity
messages: Belongs to the DprA/Smf family.

1031564:CINS RS00080
gene id: 1031564:CINS_RS00080
uniprot id: A0A0A8GZT5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1031564:CINS RS00095
gene id: 1031564:CINS_RS00095
uniprot id: A0A0A8GYR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1031564:CINS RS07115
gene id: 1031564:CINS_RS07115
uniprot id: A0A0A8H2L8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1031564:CINS RS02980
gene id: 1031564:CINS_RS02980
uniprot id: A0A0A8H3W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1031564:CINS RS05210
gene id: 1031564:CINS_RS05210
uniprot id: A0A0A8H565
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1031564:CINS RS01345
gene id: 1031564:CINS_RS01345
uniprot id: A0A0A8H2X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1031564:CINS RS05845
gene id: 1031564:CINS_RS05845
uniprot id: A0A0A8H5F5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1031564:CINS RS02280
gene id: 1031564:CINS_RS02280
uniprot id: A0A0A8H0A5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS01995
gene id: 1031564:CINS_RS01995
uniprot id: A0A0A8H057
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

1031564:CINS RS03405
gene id: 1031564:CINS_RS03405
uniprot id: A0A0A8H0F3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1031564:CINS RS01065
gene id: 1031564:CINS_RS01065
uniprot id: A0A0A8GZX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1031564:CINS RS02945
gene id: 1031564:CINS_RS02945
uniprot id: A0A0A8H0Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1031564:CINS RS06110
gene id: 1031564:CINS_RS06110
uniprot id: A0A0A8H3C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1031564:CINS RS04325
gene id: 1031564:CINS_RS04325
uniprot id: A0A0A8H0X5
names: Similarity
messages: Belongs to the threonine synthase family.

1031564:CINS RS05030
gene id: 1031564:CINS_RS05030
uniprot id: A0A0A8H537
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1031564:CINS RS05355
gene id: 1031564:CINS_RS05355
uniprot id: A0A0A8H1N7
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS02150
gene id: 1031564:CINS_RS02150
uniprot id: A0A0A8H0I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1031564:CINS RS06220
gene id: 1031564:CINS_RS06220
uniprot id: A0A0A8H279
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1031564:CINS RS00410
gene id: 1031564:CINS_RS00410
uniprot id: A0A0A8GZY6
names: Similarity
messages: Belongs to the asparaginase 1 family.

1031564:CINS RS00340
gene id: 1031564:CINS_RS00340
uniprot id: A0A0A8GZA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1031564:CINS RS01015
gene id: 1031564:CINS_RS01015
uniprot id: A0A0A8GZW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1031564:CINS RS03635
gene id: 1031564:CINS_RS03635
uniprot id: A0A0A8H470
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1031564:CINS RS04795
gene id: 1031564:CINS_RS04795
uniprot id: A0A0A8H1G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1031564:CINS RS04785
gene id: 1031564:CINS_RS04785
uniprot id: A0A0A8H4U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cytoplasm

1031564:CINS RS02590
gene id: 1031564:CINS_RS02590
uniprot id: A0A0A8H026
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS04385
gene id: 1031564:CINS_RS04385
uniprot id: A0A0A8H2E4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1031564:CINS RS01905
gene id: 1031564:CINS_RS01905
uniprot id: A0A0A8GZL9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1031564:CINS RS01555
gene id: 1031564:CINS_RS01555
uniprot id: A0A0A8H0K3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1031564:CINS RS04075
gene id: 1031564:CINS_RS04075
uniprot id: A0A0A8H0R9
names: Similarity
messages: Belongs to the DprA/Smf family.

1031564:CINS RS00445
gene id: 1031564:CINS_RS00445
uniprot id: A0A0A8GZL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1031564:CINS RS06505
gene id: 1031564:CINS_RS06505
uniprot id: A0A0A8H290
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1031564:CINS RS06240
gene id: 1031564:CINS_RS06240
uniprot id: A0A0A8H3E8
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1031564:CINS RS05220
gene id: 1031564:CINS_RS05220
uniprot id: A0A0A8H1R9
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1031564:CINS RS03580
gene id: 1031564:CINS_RS03580
uniprot id: A0A0A8H0I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1031564:CINS RS06650
gene id: 1031564:CINS_RS06650
uniprot id: A0A0A8H2T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1031564:CINS RS06690
gene id: 1031564:CINS_RS06690
uniprot id: A0A0A8H3P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1031564:CINS RS01145
gene id: 1031564:CINS_RS01145
uniprot id: A0A0A8H0C7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1031564:CINS RS06750
gene id: 1031564:CINS_RS06750
uniprot id: A0A0A8H2U7
names: Similarity
messages: Belongs to the thioredoxin family.

1031564:CINS RS03090
gene id: 1031564:CINS_RS03090
uniprot id: A0A0A8H0P6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1031564:CINS RS03015
gene id: 1031564:CINS_RS03015
uniprot id: A0A0A8H0N7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1031564:CINS RS02030
gene id: 1031564:CINS_RS02030
uniprot id: A0A0A8GZP6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1031564:CINS RS02725
gene id: 1031564:CINS_RS02725
uniprot id: A0A0A8H042
names: Similarity
messages: Belongs to the pyruvate kinase family.

1031564:CINS RS00385
gene id: 1031564:CINS_RS00385
uniprot id: A0A0A8GZY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1031564:CINS RS01340
gene id: 1031564:CINS_RS01340
uniprot id: A0A0A8GZA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1031564:CINS RS00480
gene id: 1031564:CINS_RS00480
uniprot id: A0A0A8GZZ7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS01160
gene id: 1031564:CINS_RS01160
uniprot id: A0A0A8GZ76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS05825
gene id: 1031564:CINS_RS05825
uniprot id: A0A0A8H207
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1031564:CINS RS03920
gene id: 1031564:CINS_RS03920
uniprot id: A0A0A8H0P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1031564:CINS RS02285
gene id: 1031564:CINS_RS02285
uniprot id: A0A0A8H0L2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1031564:CINS RS00460
gene id: 1031564:CINS_RS00460
uniprot id: A0A0A8GZB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1031564:CINS RS06815
gene id: 1031564:CINS_RS06815
uniprot id: A0A0A8H3S7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS05810
gene id: 1031564:CINS_RS05810
uniprot id: A0A0A8H1W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1031564:CINS RS05685
gene id: 1031564:CINS_RS05685
uniprot id: A0A0A8H5D2
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1031564:CINS RS01470
gene id: 1031564:CINS_RS01470
uniprot id: A0A0A8GZC6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1031564:CINS RS06755
gene id: 1031564:CINS_RS06755
uniprot id: A0A0A8H2E8
names: Similarity
messages: Belongs to the UPF0102 family.

1031564:CINS RS06670
gene id: 1031564:CINS_RS06670
uniprot id: A0A0A8H2H6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS02505
gene id: 1031564:CINS_RS02505
uniprot id: A0A0A8H015
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1031564:CINS RS00880
gene id: 1031564:CINS_RS00880
uniprot id: A0A0A8H069
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1031564:CINS RS07055
gene id: 1031564:CINS_RS07055
uniprot id: A0A0A8H2P8
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1031564:CINS RS06855
gene id: 1031564:CINS_RS06855
uniprot id: A0A0A8H2H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1031564:CINS RS04355
gene id: 1031564:CINS_RS04355
uniprot id: A0A0A8H4J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1031564:CINS RS05110
gene id: 1031564:CINS_RS05110
uniprot id: A0A0A8H2X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1031564:CINS RS04845
gene id: 1031564:CINS_RS04845
uniprot id: A0A0A8H1G9
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1031564:CINS RS00585
gene id: 1031564:CINS_RS00585
uniprot id: A0A0A8GZD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1031564:CINS RS03520
gene id: 1031564:CINS_RS03520
uniprot id: A0A0A8H0W9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1031564:CINS RS03280
gene id: 1031564:CINS_RS03280
uniprot id: A0A0A8H0D5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1031564:CINS RS04765
gene id: 1031564:CINS_RS04765
uniprot id: A0A0A8H2N4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

1031564:CINS RS05420
gene id: 1031564:CINS_RS05420
uniprot id: A0A0A8H1U7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1031564:CINS RS01395
gene id: 1031564:CINS_RS01395
uniprot id: A0A0A8H2Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1031564:CINS RS00305
gene id: 1031564:CINS_RS00305
uniprot id: A0A0A8H2H3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1031564:CINS RS06790
gene id: 1031564:CINS_RS06790
uniprot id: A0A0A8H3S1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1031564:CINS RS00715
gene id: 1031564:CINS_RS00715
uniprot id: A0A0A8GZ03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1031564:CINS RS07195
gene id: 1031564:CINS_RS07195
uniprot id: A0A0A8H2N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1031564:CINS RS07375
gene id: 1031564:CINS_RS07375
uniprot id: A0A0A8H438
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1031564:CINS RS00755
gene id: 1031564:CINS_RS00755
uniprot id: A0A0A8GZF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1031564:CINS RS03555
gene id: 1031564:CINS_RS03555
uniprot id: A0A0A8H0H8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS03715
gene id: 1031564:CINS_RS03715
uniprot id: A0A0A8H481
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1031564:CINS RS00220
gene id: 1031564:CINS_RS00220
uniprot id: A0A0A8GZV6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1031564:CINS RS01925
gene id: 1031564:CINS_RS01925
uniprot id: A0A0A8H0E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1031564:CINS RS03585
gene id: 1031564:CINS_RS03585
uniprot id: A0A0A8H460
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1031564:CINS RS06185
gene id: 1031564:CINS_RS06185
uniprot id: A0A0A8H5K7
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS06095
gene id: 1031564:CINS_RS06095
uniprot id: A0A0A8H2H8
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1031564:CINS RS06715
gene id: 1031564:CINS_RS06715
uniprot id: A0A0A8H3Q1
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1031564:CINS RS01645
gene id: 1031564:CINS_RS01645
uniprot id: A0A0A8GZG1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1031564:CINS RS06500
gene id: 1031564:CINS_RS06500
uniprot id: A0A0A8H2Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1031564:CINS RS06605
gene id: 1031564:CINS_RS06605
uniprot id: A0A0A8H2B2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1031564:CINS RS06245
gene id: 1031564:CINS_RS06245
uniprot id: A0A0A8H285
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1031564:CINS RS06435
gene id: 1031564:CINS_RS06435
uniprot id: A0A0A8H5Q0
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1031564:CINS RS00700
gene id: 1031564:CINS_RS00700
uniprot id: A0A0A8H036
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1031564:CINS RS02830
gene id: 1031564:CINS_RS02830
uniprot id: A0A0A8H1L0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1031564:CINS RS05055
gene id: 1031564:CINS_RS05055
uniprot id: A0A0A8H542
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1031564:CINS RS05485
gene id: 1031564:CINS_RS05485
uniprot id: A0A0A8H5A2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1031564:CINS RS03065
gene id: 1031564:CINS_RS03065
uniprot id: A0A0A8H0P4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1031564:CINS RS02105
gene id: 1031564:CINS_RS02105
uniprot id: A0A0A8H3E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1031564:CINS RS05040
gene id: 1031564:CINS_RS05040
uniprot id: A0A0A8H1P2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1031564:CINS RS06745
gene id: 1031564:CINS_RS06745
uniprot id: A0A0A8H2J4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1031564:CINS RS00440
gene id: 1031564:CINS_RS00440
uniprot id: A0A0A8GZB5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1031564:CINS RS04695
gene id: 1031564:CINS_RS04695
uniprot id: A0A0A8H1E8
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS00495
gene id: 1031564:CINS_RS00495
uniprot id: A0A0A8GYX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1031564:CINS RS06200
gene id: 1031564:CINS_RS06200
uniprot id: A0A0A8H2J5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1031564:CINS RS00705
gene id: 1031564:CINS_RS00705
uniprot id: A0A0A8GZF2
names: Caution
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS03105
gene id: 1031564:CINS_RS03105
uniprot id: A0A0A8H3Y4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1031564:CINS RS01800
gene id: 1031564:CINS_RS01800
uniprot id: A0A0A8H0B7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1031564:CINS RS02515
gene id: 1031564:CINS_RS02515
uniprot id: A0A0A8H1H5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS06840
gene id: 1031564:CINS_RS06840
uniprot id: A0A0A8H3T3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1031564:CINS RS07345
gene id: 1031564:CINS_RS07345
uniprot id: A0A0A8H2R9
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS01380
gene id: 1031564:CINS_RS01380
uniprot id: A0A0A8GZS9
names: Similarity
messages: Belongs to the RutC family.

1031564:CINS RS04935
gene id: 1031564:CINS_RS04935
uniprot id: A0A0A8H2S3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1031564:CINS RS04580
gene id: 1031564:CINS_RS04580
uniprot id: A0A0A8H122
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS03120
gene id: 1031564:CINS_RS03120
uniprot id: A0A0A8H115
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1031564:CINS RS05150
gene id: 1031564:CINS_RS05150
uniprot id: A0A0A8H1L2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1031564:CINS RS06965
gene id: 1031564:CINS_RS06965
uniprot id: A0A0A8H3W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1031564:CINS RS05090
gene id: 1031564:CINS_RS05090
uniprot id: A0A0A8H1Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1031564:CINS RS03145
gene id: 1031564:CINS_RS03145
uniprot id: A0A0A8H117
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1031564:CINS RS03690
gene id: 1031564:CINS_RS03690
uniprot id: A0A0A8H477
names: Similarity
messages: Belongs to the UbiD family.

1031564:CINS RS01595
gene id: 1031564:CINS_RS01595
uniprot id: A0A0A8GZF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1031564:CINS RS03040
gene id: 1031564:CINS_RS03040
uniprot id: A0A0A8H0P1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1031564:CINS RS01710
gene id: 1031564:CINS_RS01710
uniprot id: A0A0A8GZZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1031564:CINS RS00505
gene id: 1031564:CINS_RS00505
uniprot id: A0A0A8H002
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1031564:CINS RS07205
gene id: 1031564:CINS_RS07205
uniprot id: A0A0A8H404
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1031564:CINS RS02125
gene id: 1031564:CINS_RS02125
uniprot id: A0A0A8H0H9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1031564:CINS RS03640
gene id: 1031564:CINS_RS03640
uniprot id: A0A0A8H1Z7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1031564:CINS RS06820
gene id: 1031564:CINS_RS06820
uniprot id: A0A0A8H2L0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1031564:CINS RS01150
gene id: 1031564:CINS_RS01150
uniprot id: A0A0A8GZN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1031564:CINS RS02625
gene id: 1031564:CINS_RS02625
uniprot id: A0A0A8H1I6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1031564:CINS RS00130
gene id: 1031564:CINS_RS00130
uniprot id: A0A0A8GYR7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1031564:CINS RS01385
gene id: 1031564:CINS_RS01385
uniprot id: A0A0A8H034
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1031564:CINS RS03990
gene id: 1031564:CINS_RS03990
uniprot id: A0A0A8H1D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1031564:CINS RS00180
gene id: 1031564:CINS_RS00180
uniprot id: A0A0A8GYS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1031564:CINS RS06120
gene id: 1031564:CINS_RS06120
uniprot id: A0A0A8H2I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1031564:CINS RS06740
gene id: 1031564:CINS_RS06740
uniprot id: A0A0A8H3Q8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1031564:CINS RS03525
gene id: 1031564:CINS_RS03525
uniprot id: A0A0A8H168
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1031564:CINS RS00670
gene id: 1031564:CINS_RS00670
uniprot id: A0A0A8H031
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS02995
gene id: 1031564:CINS_RS02995
uniprot id: A0A0A8H0Z7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1031564:CINS RS02370
gene id: 1031564:CINS_RS02370
uniprot id: A0A0A8H144
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1031564:CINS RS00275
gene id: 1031564:CINS_RS00275
uniprot id: A0A0A8H2H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1031564:CINS RS03890
gene id: 1031564:CINS_RS03890
uniprot id: A0A0A8H1B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1031564:CINS RS02145
gene id: 1031564:CINS_RS02145
uniprot id: A0A0A8H085
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1031564:CINS RS02720
gene id: 1031564:CINS_RS02720
uniprot id: A0A0A8H0U9
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1031564:CINS RS03940
gene id: 1031564:CINS_RS03940
uniprot id: A0A0A8H1C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1031564:CINS RS05280
gene id: 1031564:CINS_RS05280
uniprot id: A0A0A8H1M6
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS03595
gene id: 1031564:CINS_RS03595
uniprot id: A0A0A8H0Y4
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1031564:CINS RS01855
gene id: 1031564:CINS_RS01855
uniprot id: A0A0A8GZK8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1031564:CINS RS06880
gene id: 1031564:CINS_RS06880
uniprot id: A0A0A8H2H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1031564:CINS RS04870
gene id: 1031564:CINS_RS04870
uniprot id: A0A0A8H1V4
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Periplasm

1031564:CINS RS03440
gene id: 1031564:CINS_RS03440
uniprot id: A0A0A8H1W1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1031564:CINS RS04230
gene id: 1031564:CINS_RS04230
uniprot id: A0A0A8H4G8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1031564:CINS RS03000
gene id: 1031564:CINS_RS03000
uniprot id: A0A0A8H086
names: Similarity
messages: Belongs to the peptidase M16 family.

1031564:CINS RS04835
gene id: 1031564:CINS_RS04835
uniprot id: A0A0A8H4W3
names: Similarity
messages: Belongs to the glutamine synthetase family.

1031564:CINS RS06080
gene id: 1031564:CINS_RS06080
uniprot id: A0A0A8H5J1
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1031564:CINS RS00170
gene id: 1031564:CINS_RS00170
uniprot id: A0A0A8GZ82
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1031564:CINS RS01230
gene id: 1031564:CINS_RS01230
uniprot id: A0A0A8H000
names: Similarity
messages: Belongs to the GPI family.

1031564:CINS RS00965
gene id: 1031564:CINS_RS00965
uniprot id: A0A0A8GZV8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1031564:CINS RS01815
gene id: 1031564:CINS_RS01815
uniprot id: A0A0A8H0Q6
names: Cofactor
names: Similarity
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.

1031564:CINS RS03070
gene id: 1031564:CINS_RS03070
uniprot id: A0A0A8H109
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1031564:CINS RS04375
gene id: 1031564:CINS_RS04375
uniprot id: A0A0A8H0Y7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1031564:CINS RS03500
gene id: 1031564:CINS_RS03500
uniprot id: A0A0A8H0G8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS05300
gene id: 1031564:CINS_RS05300
uniprot id: A0A0A8H255
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1031564:CINS RS05895
gene id: 1031564:CINS_RS05895
uniprot id: A0A0A8H5G3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1031564:CINS RS04295
gene id: 1031564:CINS_RS04295
uniprot id: A0A0A8H1G6
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS03590
gene id: 1031564:CINS_RS03590
uniprot id: A0A0A8H1Y8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1031564:CINS RS02910
gene id: 1031564:CINS_RS02910
uniprot id: A0A0A8H1L6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1031564:CINS RS04725
gene id: 1031564:CINS_RS04725
uniprot id: A0A0A8H1R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1031564:CINS RS01895
gene id: 1031564:CINS_RS01895
uniprot id: A0A0A8H033
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1031564:CINS RS02760
gene id: 1031564:CINS_RS02760
uniprot id: A0A0A8H1J9
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS07325
gene id: 1031564:CINS_RS07325
uniprot id: A0A0A8H682
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1031564:CINS RS05815
gene id: 1031564:CINS_RS05815
uniprot id: A0A0A8H5F2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1031564:CINS RS03800
gene id: 1031564:CINS_RS03800
uniprot id: A0A0A8H224
names: Similarity
messages: Belongs to the HypE family.

1031564:CINS RS07875
gene id: 1031564:CINS_RS07875
uniprot id: A0A0A8H2U0
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1031564:CINS RS00510
gene id: 1031564:CINS_RS00510
uniprot id: A0A0A8GZC4
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1031564:CINS RS05590
gene id: 1031564:CINS_RS05590
uniprot id: A0A0A8H335
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1031564:CINS RS05080
gene id: 1031564:CINS_RS05080
uniprot id: A0A0A8H547
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1031564:CINS RS01425
gene id: 1031564:CINS_RS01425
uniprot id: A0A0A8H0H7
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1031564:CINS RS04705
gene id: 1031564:CINS_RS04705
uniprot id: A0A0A8H141
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS06680
gene id: 1031564:CINS_RS06680
uniprot id: A0A0A8H2D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1031564:CINS RS03100
gene id: 1031564:CINS_RS03100
uniprot id: A0A0A8H0A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1031564:CINS RS07320
gene id: 1031564:CINS_RS07320
uniprot id: A0A0A8H2R4
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

1031564:CINS RS06415
gene id: 1031564:CINS_RS06415
uniprot id: A0A0A8H3I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1031564:CINS RS03110
gene id: 1031564:CINS_RS03110
uniprot id: A0A0A8H1P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1031564:CINS RS02295
gene id: 1031564:CINS_RS02295
uniprot id: A0A0A8H3I5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1031564:CINS RS01240
gene id: 1031564:CINS_RS01240
uniprot id: A0A0A8H2W3
names: Similarity
messages: Belongs to the IMPACT family.

1031564:CINS RS06525
gene id: 1031564:CINS_RS06525
uniprot id: A0A0A8H2Q8
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS07715
gene id: 1031564:CINS_RS07715
uniprot id: A0A0A8GYW3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1031564:CINS RS02815
gene id: 1031564:CINS_RS02815
uniprot id: A0A0A8H0L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1031564:CINS RS02335
gene id: 1031564:CINS_RS02335
uniprot id: A0A0A8H0M4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1031564:CINS RS06530
gene id: 1031564:CINS_RS06530
uniprot id: A0A0A8H296
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1031564:CINS RS06275
gene id: 1031564:CINS_RS06275
uniprot id: A0A0A8H2L1
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1031564:CINS RS03230
gene id: 1031564:CINS_RS03230
uniprot id: A0A0A8H0C2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1031564:CINS RS06485
gene id: 1031564:CINS_RS06485
uniprot id: A0A0A8H5Q9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1031564:CINS RS03375
gene id: 1031564:CINS_RS03375
uniprot id: A0A0A8H145
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

1031564:CINS RS02710
gene id: 1031564:CINS_RS02710
uniprot id: A0A0A8H1J2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gmhB family.
messages: Cytoplasm
messages: Monomer.

1031564:CINS RS06385
gene id: 1031564:CINS_RS06385
uniprot id: A0A0A8H5P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1031564:CINS RS00200
gene id: 1031564:CINS_RS00200
uniprot id: A0A0A8GZH9
names: Cofactor
names: Function
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Binds 1 zinc ion per subunit.

1031564:CINS RS00740
gene id: 1031564:CINS_RS00740
uniprot id: A0A0A8GZ06
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1031564:CINS RS03705
gene id: 1031564:CINS_RS03705
uniprot id: A0A0A8H194
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1031564:CINS RS07505
gene id: 1031564:CINS_RS07505
uniprot id: A0A0A8H6C4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1031564:CINS RS00790
gene id: 1031564:CINS_RS00790
uniprot id: A0A0A8GZ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1031564:CINS RS04715
gene id: 1031564:CINS_RS04715
uniprot id: A0A0A8H2M2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS01685
gene id: 1031564:CINS_RS01685
uniprot id: A0A0A8GZY7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1031564:CINS RS06360
gene id: 1031564:CINS_RS06360
uniprot id: A0A0A8H5N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1031564:CINS RS02775
gene id: 1031564:CINS_RS02775
uniprot id: A0A0A8H048
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1031564:CINS RS00905
gene id: 1031564:CINS_RS00905
uniprot id: A0A0A8H073
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1031564:CINS RS06545
gene id: 1031564:CINS_RS06545
uniprot id: A0A0A8H2E9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1031564:CINS RS01370
gene id: 1031564:CINS_RS01370
uniprot id: A0A0A8H2Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1031564:CINS RS01335
gene id: 1031564:CINS_RS01335
uniprot id: A0A0A8H021
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1031564:CINS RS05625
gene id: 1031564:CINS_RS05625
uniprot id: A0A0A8H297
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS00015
gene id: 1031564:CINS_RS00015
uniprot id: A0A0A8GZF1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1031564:CINS RS06640
gene id: 1031564:CINS_RS06640
uniprot id: A0A0A8H3N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1031564:CINS RS04630
gene id: 1031564:CINS_RS04630
uniprot id: A0A0A8H134
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1031564:CINS RS04615
gene id: 1031564:CINS_RS04615
uniprot id: A0A0A8H2J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1031564:CINS RS01320
gene id: 1031564:CINS_RS01320
uniprot id: A0A0A8H2X7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1031564:CINS RS01305
gene id: 1031564:CINS_RS01305
uniprot id: A0A0A8GZR3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1031564:CINS RS00020
gene id: 1031564:CINS_RS00020
uniprot id: A0A0A8GYQ3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1031564:CINS RS03550
gene id: 1031564:CINS_RS03550
uniprot id: A0A0A8H172
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerH subfamily.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1031564:CINS RS01640
gene id: 1031564:CINS_RS01640
uniprot id: A0A0A8H087
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: The fumarate reductase enzyme complex is required for fumarate respiration. This subunit anchors the complex in the membrane and binds a diheme cytochrome b.

1031564:CINS RS00940
gene id: 1031564:CINS_RS00940
uniprot id: A0A0A8GZV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1031564:CINS RS02110
gene id: 1031564:CINS_RS02110
uniprot id: A0A0A8H0X1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1031564:CINS RS00935
gene id: 1031564:CINS_RS00935
uniprot id: A0A0A8GZJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

1031564:CINS RS01285
gene id: 1031564:CINS_RS01285
uniprot id: A0A0A8H011
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1031564:CINS RS07350
gene id: 1031564:CINS_RS07350
uniprot id: A0A0A8H688
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS00190
gene id: 1031564:CINS_RS00190
uniprot id: A0A0A8GZV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

1031564:CINS RS00150
gene id: 1031564:CINS_RS00150
uniprot id: A0A0A8GZH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1031564:CINS RS01755
gene id: 1031564:CINS_RS01755
uniprot id: A0A0A8H368
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1031564:CINS RS04780
gene id: 1031564:CINS_RS04780
uniprot id: A0A0A8H161
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1031564:CINS RS05740
gene id: 1031564:CINS_RS05740
uniprot id: A0A0A8H359
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1031564:CINS RS07440
gene id: 1031564:CINS_RS07440
uniprot id: A0A0A8H2T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1031564:CINS RS05035
gene id: 1031564:CINS_RS05035
uniprot id: A0A0A8H2W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1031564:CINS RS06540
gene id: 1031564:CINS_RS06540
uniprot id: A0A0A8H3L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1031564:CINS RS07265
gene id: 1031564:CINS_RS07265
uniprot id: A0A0A8H342
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1031564:CINS RS07480
gene id: 1031564:CINS_RS07480
uniprot id: A0A0A8H2Y0
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1031564:CINS RS03810
gene id: 1031564:CINS_RS03810
uniprot id: A0A0A8H1A9
names: Similarity
messages: Belongs to the HupF/HypC family.

1031564:CINS RS03455
gene id: 1031564:CINS_RS03455
uniprot id: A0A0A8H0F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1031564:CINS RS03605
gene id: 1031564:CINS_RS03605
uniprot id: A0A0A8H0I9
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.

1031564:CINS RS04560
gene id: 1031564:CINS_RS04560
uniprot id: A0A0A8H4P7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS06495
gene id: 1031564:CINS_RS06495
uniprot id: A0A0A8H2D6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1031564:CINS RS05775
gene id: 1031564:CINS_RS05775
uniprot id: A0A0A8H2C2
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS01450
gene id: 1031564:CINS_RS01450
uniprot id: A0A0A8H0I2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS04685
gene id: 1031564:CINS_RS04685
uniprot id: A0A0A8H4S8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1031564:CINS RS00315
gene id: 1031564:CINS_RS00315
uniprot id: A0A0A8GZ98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1031564:CINS RS01790
gene id: 1031564:CINS_RS01790
uniprot id: A0A0A8H0Q1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1031564:CINS RS01650
gene id: 1031564:CINS_RS01650
uniprot id: A0A0A8H340
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1031564:CINS RS07145
gene id: 1031564:CINS_RS07145
uniprot id: A0A0A8H2M5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1031564:CINS RS05595
gene id: 1031564:CINS_RS05595
uniprot id: A0A0A8H1X3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1031564:CINS RS00065
gene id: 1031564:CINS_RS00065
uniprot id: A0A0A8GZF8
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS05115
gene id: 1031564:CINS_RS05115
uniprot id: A0A0A8H1Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1031564:CINS RS00070
gene id: 1031564:CINS_RS00070
uniprot id: A0A0A8GYR1
names: Similarity
messages: Belongs to the RecJ family.

1031564:CINS RS04315
gene id: 1031564:CINS_RS04315
uniprot id: A0A0A8H1A6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS05750
gene id: 1031564:CINS_RS05750
uniprot id: A0A0A8H2B7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1031564:CINS RS02825
gene id: 1031564:CINS_RS02825
uniprot id: A0A0A8H3U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1031564:CINS RS05335
gene id: 1031564:CINS_RS05335
uniprot id: A0A0A8H581
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS00030
gene id: 1031564:CINS_RS00030
uniprot id: A0A0A8GZS5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1031564:CINS RS03400
gene id: 1031564:CINS_RS03400
uniprot id: A0A0A8H149
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1031564:CINS RS03620
gene id: 1031564:CINS_RS03620
uniprot id: A0A0A8H0Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1031564:CINS RS06795
gene id: 1031564:CINS_RS06795
uniprot id: A0A0A8H2K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1031564:CINS RS05075
gene id: 1031564:CINS_RS05075
uniprot id: A0A0A8H1K0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1031564:CINS RS03020
gene id: 1031564:CINS_RS03020
uniprot id: A0A0A8H102
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1031564:CINS RS00250
gene id: 1031564:CINS_RS00250
uniprot id: A0A0A8GZW2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1031564:CINS RS06410
gene id: 1031564:CINS_RS06410
uniprot id: A0A0A8H5P5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1031564:CINS RS02045
gene id: 1031564:CINS_RS02045
uniprot id: A0A0A8H067
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1031564:CINS RS02130
gene id: 1031564:CINS_RS02130
uniprot id: A0A0A8GZR5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1031564:CINS RS07245
gene id: 1031564:CINS_RS07245
uniprot id: A0A0A8H2P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1031564:CINS RS04960
gene id: 1031564:CINS_RS04960
uniprot id: A0A0A8H2S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1031564:CINS RS03430
gene id: 1031564:CINS_RS03430
uniprot id: A0A0A8H0F7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1031564:CINS RS06270
gene id: 1031564:CINS_RS06270
uniprot id: A0A0A8H289
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS02025
gene id: 1031564:CINS_RS02025
uniprot id: A0A0A8H0G0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1031564:CINS RS02155
gene id: 1031564:CINS_RS02155
uniprot id: A0A0A8GZS0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1031564:CINS RS00910
gene id: 1031564:CINS_RS00910
uniprot id: A0A0A8GZI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1031564:CINS RS06970
gene id: 1031564:CINS_RS06970
uniprot id: A0A0A8H2P2
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1031564:CINS RS03360
gene id: 1031564:CINS_RS03360
uniprot id: A0A0A8H424
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS07210
gene id: 1031564:CINS_RS07210
uniprot id: A0A0A8H2T2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS03460
gene id: 1031564:CINS_RS03460
uniprot id: A0A0A8H441
names: Similarity
messages: Belongs to the peptidase A31 family.

1031564:CINS RS05165
gene id: 1031564:CINS_RS05165
uniprot id: A0A0A8H1R3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.

1031564:CINS RS00895
gene id: 1031564:CINS_RS00895
uniprot id: A0A0A8GZ27
names: Similarity
messages: Belongs to the ParB family.

1031564:CINS RS05780
gene id: 1031564:CINS_RS05780
uniprot id: A0A0A8H1V8
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS06585
gene id: 1031564:CINS_RS06585
uniprot id: A0A0A8H5S2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

1031564:CINS RS01970
gene id: 1031564:CINS_RS01970
uniprot id: A0A0A8H052
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1031564:CINS RS04540
gene id: 1031564:CINS_RS04540
uniprot id: A0A0A8H2I1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1031564:CINS RS04470
gene id: 1031564:CINS_RS04470
uniprot id: A0A0A8H1C8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1031564:CINS RS04395
gene id: 1031564:CINS_RS04395
uniprot id: A0A0A8H1I5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1031564:CINS RS05715
gene id: 1031564:CINS_RS05715
uniprot id: A0A0A8H354
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1031564:CINS RS06450
gene id: 1031564:CINS_RS06450
uniprot id: A0A0A8H2P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1031564:CINS RS02490
gene id: 1031564:CINS_RS02490
uniprot id: A0A0A8H1H2
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS00365
gene id: 1031564:CINS_RS00365
uniprot id: A0A0A8GZA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1031564:CINS RS03820
gene id: 1031564:CINS_RS03820
uniprot id: A0A0A8H497
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1031564:CINS RS05100
gene id: 1031564:CINS_RS05100
uniprot id: A0A0A8H1K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1031564:CINS RS01775
gene id: 1031564:CINS_RS01775
uniprot id: A0A0A8H0B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1031564:CINS RS05430
gene id: 1031564:CINS_RS05430
uniprot id: A0A0A8H1P6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1031564:CINS RS05385
gene id: 1031564:CINS_RS05385
uniprot id: A0A0A8H588
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS02955
gene id: 1031564:CINS_RS02955
uniprot id: A0A0A8H3W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1031564:CINS RS02550
gene id: 1031564:CINS_RS02550
uniprot id: A0A0A8H0H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1031564:CINS RS06390
gene id: 1031564:CINS_RS06390
uniprot id: A0A0A8H3I1
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1031564:CINS RS00485
gene id: 1031564:CINS_RS00485
uniprot id: A0A0A8GZC0
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

1031564:CINS RS00135
gene id: 1031564:CINS_RS00135
uniprot id: A0A0A8H2F2
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS00230
gene id: 1031564:CINS_RS00230
uniprot id: A0A0A8GZ89
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS03645
gene id: 1031564:CINS_RS03645
uniprot id: A0A0A8H0Z0
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

1031564:CINS RS04760
gene id: 1031564:CINS_RS04760
uniprot id: A0A0A8H4U4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1031564:CINS RS00005
gene id: 1031564:CINS_RS00005
uniprot id: A0A0A8GZS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1031564:CINS RS05230
gene id: 1031564:CINS_RS05230
uniprot id: A0A0A8H1M0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1031564:CINS RS04575
gene id: 1031564:CINS_RS04575
uniprot id: A0A0A8H1M2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

1031564:CINS RS06280
gene id: 1031564:CINS_RS06280
uniprot id: A0A0A8H242
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1031564:CINS RS01330
gene id: 1031564:CINS_RS01330
uniprot id: A0A0A8GZR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1031564:CINS RS04390
gene id: 1031564:CINS_RS04390
uniprot id: A0A0A8H1B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell membrane

1031564:CINS RS05025
gene id: 1031564:CINS_RS05025
uniprot id: A0A0A8H1J3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1031564:CINS RS01675
gene id: 1031564:CINS_RS01675
uniprot id: A0A0A8H348
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1031564:CINS RS07460
gene id: 1031564:CINS_RS07460
uniprot id: A0A0A8H393
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1031564:CINS RS01865
gene id: 1031564:CINS_RS01865
uniprot id: A0A0A8H0R6
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1031564:CINS RS01210
gene id: 1031564:CINS_RS01210
uniprot id: A0A0A8GZ85
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS00925
gene id: 1031564:CINS_RS00925
uniprot id: A0A0A8H2R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1031564:CINS RS02675
gene id: 1031564:CINS_RS02675
uniprot id: A0A0A8H032
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

1031564:CINS RS00955
gene id: 1031564:CINS_RS00955
uniprot id: A0A0A8H083
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

1031564:CINS RS01295
gene id: 1031564:CINS_RS01295
uniprot id: A0A0A8H2X2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1031564:CINS RS06945
gene id: 1031564:CINS_RS06945
uniprot id: A0A0A8H2N7
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS02685
gene id: 1031564:CINS_RS02685
uniprot id: A0A0A8H1I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1031564:CINS RS00345
gene id: 1031564:CINS_RS00345
uniprot id: A0A0A8GZK0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1031564:CINS RS03950
gene id: 1031564:CINS_RS03950
uniprot id: A0A0A8H4B6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1031564:CINS RS00970
gene id: 1031564:CINS_RS00970
uniprot id: A0A0A8GZ42
names: Similarity
messages: Belongs to the fabD family.

1031564:CINS RS04625
gene id: 1031564:CINS_RS04625
uniprot id: A0A0A8H1N5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S16 family.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1031564:CINS RS06055
gene id: 1031564:CINS_RS06055
uniprot id: A0A0A8H5I8
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS01565
gene id: 1031564:CINS_RS01565
uniprot id: A0A0A8H070
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1031564:CINS RS01105
gene id: 1031564:CINS_RS01105
uniprot id: A0A0A8GZY0
names: Similarity
messages: Belongs to the peptidase S49 family.

1031564:CINS RS02175
gene id: 1031564:CINS_RS02175
uniprot id: A0A0A8H0J6
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS02055
gene id: 1031564:CINS_RS02055
uniprot id: A0A0A8GZQ2
names: Subcellular Location Annotation
messages: Periplasm

1031564:CINS RS02920
gene id: 1031564:CINS_RS02920
uniprot id: A0A0A8H0X6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS02460
gene id: 1031564:CINS_RS02460
uniprot id: A0A0A8H3P5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1031564:CINS RS06425
gene id: 1031564:CINS_RS06425
uniprot id: A0A0A8H2N8
names: Similarity
messages: Belongs to the MotB family.

1031564:CINS RS00060
gene id: 1031564:CINS_RS00060
uniprot id: A0A0A8GZ68
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS05620
gene id: 1031564:CINS_RS05620
uniprot id: A0A0A8H1X8
names: Subcellular Location Annotation
messages: Membrane

1031564:CINS RS02735
gene id: 1031564:CINS_RS02735
uniprot id: A0A0A8H1J5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1031564:CINS RS02015
gene id: 1031564:CINS_RS02015
uniprot id: A0A0A8H0V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1031564:CINS RS06480
gene id: 1031564:CINS_RS06480
uniprot id: A0A0A8H286
names: Cofactor
names: Function
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Binds 1 zinc ion per subunit.

1031564:CINS RS06465
gene id: 1031564:CINS_RS06465
uniprot id: A0A0A8H3J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1031564:CINS RS07430
gene id: 1031564:CINS_RS07430
uniprot id: A0A0A8H2X0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1031564:CINS RS04985
gene id: 1031564:CINS_RS04985
uniprot id: A0A0A8H2T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1031564:CINS RS06145
gene id: 1031564:CINS_RS06145
uniprot id: A0A0A8H263
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1031564:CINS RS00325
gene id: 1031564:CINS_RS00325
uniprot id: A0A0A8GYU4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1031564:CINS RS02315
gene id: 1031564:CINS_RS02315
uniprot id: A0A0A8GZU9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1031564:CINS RS02690
gene id: 1031564:CINS_RS02690
uniprot id: A0A0A8H0J0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS01850
gene id: 1031564:CINS_RS01850
uniprot id: A0A0A8H0C8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1031564:CINS RS03290
gene id: 1031564:CINS_RS03290
uniprot id: A0A0A8H1T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1031564:CINS RS04320
gene id: 1031564:CINS_RS04320
uniprot id: A0A0A8H1H0
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1031564:CINS RS04545
gene id: 1031564:CINS_RS04545
uniprot id: A0A0A8H1D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1031564:CINS RS04890
gene id: 1031564:CINS_RS04890
uniprot id: A0A0A8H1I2
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1031564:CINS RS06400
gene id: 1031564:CINS_RS06400
uniprot id: A0A0A8H2N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1031564:CINS RS05695
gene id: 1031564:CINS_RS05695
uniprot id: A0A0A8H1Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1031564:CINS RS07295
gene id: 1031564:CINS_RS07295
uniprot id: A0A0A8H2Q7
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1031564:CINS RS00915
gene id: 1031564:CINS_RS00915
uniprot id: W6A0C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1031564:CINS RS00300
gene id: 1031564:CINS_RS00300
uniprot id: A0A0A8GYU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1031564:CINS RS03710
gene id: 1031564:CINS_RS03710
uniprot id: A0A0A8H0K7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1031564:CINS RS04670
gene id: 1031564:CINS_RS04670
uniprot id: A0A0A8H1E6
names: Subcellular Location Annotation
messages: Membrane