1029756:W911 RS11045
gene id: 1029756:W911_RS11045
uniprot id: V5SEC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1029756:W911 RS02665
gene id: 1029756:W911_RS02665
uniprot id: V5SA95
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1029756:W911 RS13960
gene id: 1029756:W911_RS13960
uniprot id: V5SFR0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1029756:W911 RS08915
gene id: 1029756:W911_RS08915
uniprot id: V5SCB8
names: PTM
messages: Binds 1 heme group per subunit.

1029756:W911 RS15915
gene id: 1029756:W911_RS15915
uniprot id: V5SHU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1029756:W911 RS14105
gene id: 1029756:W911_RS14105
uniprot id: V5SHD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methanol dehydrogenase subunit 2 family.
messages: Catalyzes the oxidation of primary alcohols including methanol.
messages: Heterotetramer composed of 2 alpha and 2 beta subunits.

1029756:W911 RS11920
gene id: 1029756:W911_RS11920
uniprot id: V5SDQ9
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS02405
gene id: 1029756:W911_RS02405
uniprot id: V5SAR8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1029756:W911 RS15565
gene id: 1029756:W911_RS15565
uniprot id: V5SGA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1029756:W911 RS01085
gene id: 1029756:W911_RS01085
uniprot id: V5S9L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1029756:W911 RS10765
gene id: 1029756:W911_RS10765
uniprot id: V5SEB5
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1029756:W911 RS01295
gene id: 1029756:W911_RS01295
uniprot id: V5SBK8
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1029756:W911 RS17170
gene id: 1029756:W911_RS17170
uniprot id: V5SAJ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1029756:W911 RS12050
gene id: 1029756:W911_RS12050
uniprot id: V5SEV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1029756:W911 RS13540
gene id: 1029756:W911_RS13540
uniprot id: V5SGV7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1029756:W911 RS16495
gene id: 1029756:W911_RS16495
uniprot id: V5SGN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1029756:W911 RS08215
gene id: 1029756:W911_RS08215
uniprot id: V5SEN9
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1029756:W911 RS03650
gene id: 1029756:W911_RS03650
uniprot id: V5SB42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1029756:W911 RS13615
gene id: 1029756:W911_RS13615
uniprot id: V5SGX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1029756:W911 RS08560
gene id: 1029756:W911_RS08560
uniprot id: V5SEK0
names: Similarity
messages: Belongs to the DEAD box helicase family.

1029756:W911 RS06375
gene id: 1029756:W911_RS06375
uniprot id: V5SC68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1029756:W911 RS13445
gene id: 1029756:W911_RS13445
uniprot id: V5SH15
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Membrane

1029756:W911 RS07700
gene id: 1029756:W911_RS07700
uniprot id: V5SBU4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1029756:W911 RS01910
gene id: 1029756:W911_RS01910
uniprot id: V5S9Y9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1029756:W911 RS13650
gene id: 1029756:W911_RS13650
uniprot id: V5SFN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1029756:W911 RS15085
gene id: 1029756:W911_RS15085
uniprot id: V5SHE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1029756:W911 RS13390
gene id: 1029756:W911_RS13390
uniprot id: V5SGT3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1029756:W911 RS07505
gene id: 1029756:W911_RS07505
uniprot id: V5SCW4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1029756:W911 RS01875
gene id: 1029756:W911_RS01875
uniprot id: V5S9L9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1029756:W911 RS16945
gene id: 1029756:W911_RS16945
uniprot id: V5SFV0
names: Similarity
messages: Belongs to the peptidase S58 family.

1029756:W911 RS13675
gene id: 1029756:W911_RS13675
uniprot id: V5SFN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1029756:W911 RS13090
gene id: 1029756:W911_RS13090
uniprot id: V5SE79
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1029756:W911 RS13160
gene id: 1029756:W911_RS13160
uniprot id: V5SFD1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1029756:W911 RS06885
gene id: 1029756:W911_RS06885
uniprot id: V5SCE3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1029756:W911 RS09945
gene id: 1029756:W911_RS09945
uniprot id: V5SDX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

1029756:W911 RS03170
gene id: 1029756:W911_RS03170
uniprot id: V5SB04
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1029756:W911 RS16730
gene id: 1029756:W911_RS16730
uniprot id: V5SFR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1029756:W911 RS07005
gene id: 1029756:W911_RS07005
uniprot id: V5SBD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1029756:W911 RS03305
gene id: 1029756:W911_RS03305
uniprot id: V5SB09
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1029756:W911 RS00350
gene id: 1029756:W911_RS00350
uniprot id: V5S8V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1029756:W911 RS05430
gene id: 1029756:W911_RS05430
uniprot id: V5SBX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1029756:W911 RS00660
gene id: 1029756:W911_RS00660
uniprot id: V5S906
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1029756:W911 RS01510
gene id: 1029756:W911_RS01510
uniprot id: V5SAB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1029756:W911 RS03785
gene id: 1029756:W911_RS03785
uniprot id: V5SAE9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1029756:W911 RS02275
gene id: 1029756:W911_RS02275
uniprot id: V5SC05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1029756:W911 RS07900
gene id: 1029756:W911_RS07900
uniprot id: V5SCX4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1029756:W911 RS13595
gene id: 1029756:W911_RS13595
uniprot id: V5SEG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1029756:W911 RS15965
gene id: 1029756:W911_RS15965
uniprot id: V5SHV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS13990
gene id: 1029756:W911_RS13990
uniprot id: V5SFR4
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1029756:W911 RS13055
gene id: 1029756:W911_RS13055
uniprot id: V5SE72
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS07200
gene id: 1029756:W911_RS07200
uniprot id: V5SBH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS13785
gene id: 1029756:W911_RS13785
uniprot id: V5SEN2
names: Similarity
messages: Belongs to the UPF0145 family.

1029756:W911 RS06415
gene id: 1029756:W911_RS06415
uniprot id: V5SDJ4
names: Similarity
messages: Belongs to the UPF0178 family.

1029756:W911 RS15920
gene id: 1029756:W911_RS15920
uniprot id: V5SFG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1029756:W911 RS16670
gene id: 1029756:W911_RS16670
uniprot id: V5SIE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1029756:W911 RS15070
gene id: 1029756:W911_RS15070
uniprot id: V5SG54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1029756:W911 RS10110
gene id: 1029756:W911_RS10110
uniprot id: V5SE01
names: Similarity
messages: Belongs to the glutamine synthetase family.

1029756:W911 RS05880
gene id: 1029756:W911_RS05880
uniprot id: V5SB29
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1029756:W911 RS03775
gene id: 1029756:W911_RS03775
uniprot id: V5SCN7
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1029756:W911 RS16035
gene id: 1029756:W911_RS16035
uniprot id: V5SGL4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1029756:W911 RS01730
gene id: 1029756:W911_RS01730
uniprot id: V5SBR0
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS01185
gene id: 1029756:W911_RS01185
uniprot id: V5S9C0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1029756:W911 RS16315
gene id: 1029756:W911_RS16315
uniprot id: V5SI05
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS15220
gene id: 1029756:W911_RS15220
uniprot id: V5SHH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1029756:W911 RS02505
gene id: 1029756:W911_RS02505
uniprot id: V5S9X6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1029756:W911 RS03240
gene id: 1029756:W911_RS03240
uniprot id: V5SCA7
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.

1029756:W911 RS02060
gene id: 1029756:W911_RS02060
uniprot id: V5SAJ9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1029756:W911 RS14460
gene id: 1029756:W911_RS14460
uniprot id: V5SFS4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1029756:W911 RS02540
gene id: 1029756:W911_RS02540
uniprot id: V5SA80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1029756:W911 RS05980
gene id: 1029756:W911_RS05980
uniprot id: V5SDN0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

1029756:W911 RS05395
gene id: 1029756:W911_RS05395
uniprot id: V5SD37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1029756:W911 RS06800
gene id: 1029756:W911_RS06800
uniprot id: V5SCG1
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.

1029756:W911 RS02200
gene id: 1029756:W911_RS02200
uniprot id: V5SAM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1029756:W911 RS01700
gene id: 1029756:W911_RS01700
uniprot id: V5S9V0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1029756:W911 RS14755
gene id: 1029756:W911_RS14755
uniprot id: V5SHA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1029756:W911 RS13745
gene id: 1029756:W911_RS13745
uniprot id: V5SHA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1029756:W911 RS11485
gene id: 1029756:W911_RS11485
uniprot id: V5SFX4
names: Similarity
messages: Belongs to the ArsC family.

1029756:W911 RS08115
gene id: 1029756:W911_RS08115
uniprot id: V5SD47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1029756:W911 RS10935
gene id: 1029756:W911_RS10935
uniprot id: V5SFQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1029756:W911 RS14445
gene id: 1029756:W911_RS14445
uniprot id: V5SH57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1029756:W911 RS16700
gene id: 1029756:W911_RS16700
uniprot id: V5SI57
names: Similarity
messages: Belongs to the thioredoxin family.

1029756:W911 RS07250
gene id: 1029756:W911_RS07250
uniprot id: V5SE70
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1029756:W911 RS12730
gene id: 1029756:W911_RS12730
uniprot id: V5SF35
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

1029756:W911 RS08660
gene id: 1029756:W911_RS08660
uniprot id: V5SC84
names: Similarity
messages: Belongs to the YciI family.

1029756:W911 RS11095
gene id: 1029756:W911_RS11095
uniprot id: V5SFS3
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1029756:W911 RS02235
gene id: 1029756:W911_RS02235
uniprot id: V5SC00
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1029756:W911 RS00185
gene id: 1029756:W911_RS00185
uniprot id: V5S963
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1029756:W911 RS06035
gene id: 1029756:W911_RS06035
uniprot id: V5SC12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1029756:W911 RS02895
gene id: 1029756:W911_RS02895
uniprot id: V5SCA6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1029756:W911 RS09040
gene id: 1029756:W911_RS09040
uniprot id: V5SCD8
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1029756:W911 RS14840
gene id: 1029756:W911_RS14840
uniprot id: V5SHM5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1029756:W911 RS06215
gene id: 1029756:W911_RS06215
uniprot id: V5SB58
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1029756:W911 RS12725
gene id: 1029756:W911_RS12725
uniprot id: V5SF65
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

1029756:W911 RS15625
gene id: 1029756:W911_RS15625
uniprot id: V5SGE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

1029756:W911 RS15395
gene id: 1029756:W911_RS15395
uniprot id: V5SF82
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

1029756:W911 RS04230
gene id: 1029756:W911_RS04230
uniprot id: V5SAP3
names: Function
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.

1029756:W911 RS07335
gene id: 1029756:W911_RS07335
uniprot id: V5SBK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1029756:W911 RS14510
gene id: 1029756:W911_RS14510
uniprot id: V5SH64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1029756:W911 RS02930
gene id: 1029756:W911_RS02930
uniprot id: V5SA43
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1029756:W911 RS06650
gene id: 1029756:W911_RS06650
uniprot id: V5SCF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1029756:W911 RS02840
gene id: 1029756:W911_RS02840
uniprot id: V5SC40
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1029756:W911 RS00475
gene id: 1029756:W911_RS00475
uniprot id: V5SB81
names: Similarity
messages: Belongs to the asparagine synthetase family.

1029756:W911 RS04195
gene id: 1029756:W911_RS04195
uniprot id: V5SCY7
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1029756:W911 RS16345
gene id: 1029756:W911_RS16345
uniprot id: V5SJZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1029756:W911 RS10365
gene id: 1029756:W911_RS10365
uniprot id: V5SE10
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1029756:W911 RS08345
gene id: 1029756:W911_RS08345
uniprot id: V5SD35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1029756:W911 RS02720
gene id: 1029756:W911_RS02720
uniprot id: V5SAA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1029756:W911 RS06125
gene id: 1029756:W911_RS06125
uniprot id: V5SGP0
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS18825
gene id: 1029756:W911_RS18825
uniprot id: V5SJW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1029756:W911 RS10480
gene id: 1029756:W911_RS10480
uniprot id: V5SFN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1029756:W911 RS03110
gene id: 1029756:W911_RS03110
uniprot id: V5SB02
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1029756:W911 RS09760
gene id: 1029756:W911_RS09760
uniprot id: V5SDQ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1029756:W911 RS03090
gene id: 1029756:W911_RS03090
uniprot id: V5SAG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS09885
gene id: 1029756:W911_RS09885
uniprot id: V5SCQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1029756:W911 RS10345
gene id: 1029756:W911_RS10345
uniprot id: V5SFE0
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1029756:W911 RS13545
gene id: 1029756:W911_RS13545
uniprot id: V5SEF4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1029756:W911 RS02770
gene id: 1029756:W911_RS02770
uniprot id: V5SAW6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1029756:W911 RS15295
gene id: 1029756:W911_RS15295
uniprot id: V5SHU6
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1029756:W911 RS12540
gene id: 1029756:W911_RS12540
uniprot id: V5SF04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1029756:W911 RS04005
gene id: 1029756:W911_RS04005
uniprot id: V5SBA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1029756:W911 RS15940
gene id: 1029756:W911_RS15940
uniprot id: V5SHU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1029756:W911 RS13740
gene id: 1029756:W911_RS13740
uniprot id: V5SFL6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1029756:W911 RS03960
gene id: 1029756:W911_RS03960
uniprot id: V5SAS9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1029756:W911 RS15455
gene id: 1029756:W911_RS15455
uniprot id: V5SG85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1029756:W911 RS07370
gene id: 1029756:W911_RS07370
uniprot id: V5SCP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1029756:W911 RS10750
gene id: 1029756:W911_RS10750
uniprot id: V5SFV9
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1029756:W911 RS13320
gene id: 1029756:W911_RS13320
uniprot id: V5SGS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

1029756:W911 RS05990
gene id: 1029756:W911_RS05990
uniprot id: V5SDC3
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

1029756:W911 RS13685
gene id: 1029756:W911_RS13685
uniprot id: V5SH93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1029756:W911 RS11905
gene id: 1029756:W911_RS11905
uniprot id: V5SEQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1029756:W911 RS01615
gene id: 1029756:W911_RS01615
uniprot id: V5S9H7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1029756:W911 RS03840
gene id: 1029756:W911_RS03840
uniprot id: V5SCJ4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1029756:W911 RS10795
gene id: 1029756:W911_RS10795
uniprot id: V5SD91
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1029756:W911 RS02985
gene id: 1029756:W911_RS02985
uniprot id: V5SC65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1029756:W911 RS08015
gene id: 1029756:W911_RS08015
uniprot id: V5SBY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1029756:W911 RS11645
gene id: 1029756:W911_RS11645
uniprot id: V5SDL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS15035
gene id: 1029756:W911_RS15035
uniprot id: V5SG49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1029756:W911 RS15560
gene id: 1029756:W911_RS15560
uniprot id: V5SGE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1029756:W911 RS10010
gene id: 1029756:W911_RS10010
uniprot id: V5SF81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1029756:W911 RS07440
gene id: 1029756:W911_RS07440
uniprot id: V5SE41
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1029756:W911 RS08585
gene id: 1029756:W911_RS08585
uniprot id: V5SEU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1029756:W911 RS08170
gene id: 1029756:W911_RS08170
uniprot id: V5SED5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1029756:W911 RS03905
gene id: 1029756:W911_RS03905
uniprot id: V5SB90
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1029756:W911 RS07055
gene id: 1029756:W911_RS07055
uniprot id: V5SBD8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1029756:W911 RS01880
gene id: 1029756:W911_RS01880
uniprot id: V5SAH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1029756:W911 RS04385
gene id: 1029756:W911_RS04385
uniprot id: V5SCS4
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1029756:W911 RS02105
gene id: 1029756:W911_RS02105
uniprot id: V5S9Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1029756:W911 RS12775
gene id: 1029756:W911_RS12775
uniprot id: V5SGI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

1029756:W911 RS13030
gene id: 1029756:W911_RS13030
uniprot id: V5SE68
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1029756:W911 RS11540
gene id: 1029756:W911_RS11540
uniprot id: V5SG70
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1029756:W911 RS15400
gene id: 1029756:W911_RS15400
uniprot id: V5SGB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1029756:W911 RS08070
gene id: 1029756:W911_RS08070
uniprot id: V5SEC1
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1029756:W911 RS07870
gene id: 1029756:W911_RS07870
uniprot id: V5SCX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.

1029756:W911 RS03290
gene id: 1029756:W911_RS03290
uniprot id: V5SCH5
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

1029756:W911 RS11480
gene id: 1029756:W911_RS11480
uniprot id: V5SG57
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1029756:W911 RS16655
gene id: 1029756:W911_RS16655
uniprot id: V5SFP6
names: Subcellular Location Annotation
messages: Mitochondrion

1029756:W911 RS01690
gene id: 1029756:W911_RS01690
uniprot id: V5S9I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1029756:W911 RS10225
gene id: 1029756:W911_RS10225
uniprot id: V5SCV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1029756:W911 RS09750
gene id: 1029756:W911_RS09750
uniprot id: V5SDU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

1029756:W911 RS07345
gene id: 1029756:W911_RS07345
uniprot id: V5SCN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1029756:W911 RS00125
gene id: 1029756:W911_RS00125
uniprot id: V5S9M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS09645
gene id: 1029756:W911_RS09645
uniprot id: V5SI12
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS03920
gene id: 1029756:W911_RS03920
uniprot id: V5SCL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1029756:W911 RS16330
gene id: 1029756:W911_RS16330
uniprot id: V5SKD6
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS17020
gene id: 1029756:W911_RS17020
uniprot id: V5S9R6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1029756:W911 RS09050
gene id: 1029756:W911_RS09050
uniprot id: V5SDI4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1029756:W911 RS13300
gene id: 1029756:W911_RS13300
uniprot id: V5SEB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1029756:W911 RS08605
gene id: 1029756:W911_RS08605
uniprot id: V5SD79
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1029756:W911 RS03815
gene id: 1029756:W911_RS03815
uniprot id: V5SB68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1029756:W911 RS09370
gene id: 1029756:W911_RS09370
uniprot id: V5SEX5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1029756:W911 RS00425
gene id: 1029756:W911_RS00425
uniprot id: V5SH36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1029756:W911 RS07160
gene id: 1029756:W911_RS07160
uniprot id: V5SCK1
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS12720
gene id: 1029756:W911_RS12720
uniprot id: V5SE29
names: Similarity
messages: Belongs to the PqqA family.

1029756:W911 RS00825
gene id: 1029756:W911_RS00825
uniprot id: V5S9G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1029756:W911 RS12610
gene id: 1029756:W911_RS12610
uniprot id: V5SGF0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1029756:W911 RS13080
gene id: 1029756:W911_RS13080
uniprot id: V5SGN2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1029756:W911 RS02605
gene id: 1029756:W911_RS02605
uniprot id: V5SA86
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1029756:W911 RS14435
gene id: 1029756:W911_RS14435
uniprot id: V5SFS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

1029756:W911 RS11270
gene id: 1029756:W911_RS11270
uniprot id: V5SEI5
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1029756:W911 RS03705
gene id: 1029756:W911_RS03705
uniprot id: V5SB56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1029756:W911 RS13255
gene id: 1029756:W911_RS13255
uniprot id: V5SFE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1029756:W911 RS11020
gene id: 1029756:W911_RS11020
uniprot id: V5SEC3
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS03310
gene id: 1029756:W911_RS03310
uniprot id: V5SAK9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1029756:W911 RS16450
gene id: 1029756:W911_RS16450
uniprot id: V5SFL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1029756:W911 RS01165
gene id: 1029756:W911_RS01165
uniprot id: V5S9N3
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS10890
gene id: 1029756:W911_RS10890
uniprot id: V5SDA6
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

1029756:W911 RS11515
gene id: 1029756:W911_RS11515
uniprot id: V5SFX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1029756:W911 RS13205
gene id: 1029756:W911_RS13205
uniprot id: V5SGQ0
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1029756:W911 RS01670
gene id: 1029756:W911_RS01670
uniprot id: V5S9U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1029756:W911 RS15205
gene id: 1029756:W911_RS15205
uniprot id: V5SG80
names: Subcellular Location Annotation
messages: Cytoplasm

1029756:W911 RS11135
gene id: 1029756:W911_RS11135
uniprot id: V5SFS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS15925
gene id: 1029756:W911_RS15925
uniprot id: V5SGJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

1029756:W911 RS01395
gene id: 1029756:W911_RS01395
uniprot id: V5S9E8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1029756:W911 RS16440
gene id: 1029756:W911_RS16440
uniprot id: V5SIB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1029756:W911 RS03875
gene id: 1029756:W911_RS03875
uniprot id: V5SB87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

1029756:W911 RS15265
gene id: 1029756:W911_RS15265
uniprot id: V5SJW8
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS03300
gene id: 1029756:W911_RS03300
uniprot id: V5SAA0
names: Subcellular Location Annotation
messages: Cytoplasm

1029756:W911 RS14400
gene id: 1029756:W911_RS14400
uniprot id: V5SFR6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1029756:W911 RS15820
gene id: 1029756:W911_RS15820
uniprot id: V5SI34
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

1029756:W911 RS11015
gene id: 1029756:W911_RS11015
uniprot id: V5SEF0
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1029756:W911 RS11580
gene id: 1029756:W911_RS11580
uniprot id: V5SG73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Membrane

1029756:W911 RS06855
gene id: 1029756:W911_RS06855
uniprot id: V5SCD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1029756:W911 RS01955
gene id: 1029756:W911_RS01955
uniprot id: V5SBN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1029756:W911 RS09120
gene id: 1029756:W911_RS09120
uniprot id: V5SDJ5
names: Cofactor
messages: Can also use Mn(2+) ion.

1029756:W911 RS10625
gene id: 1029756:W911_RS10625
uniprot id: V5SFT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1029756:W911 RS12390
gene id: 1029756:W911_RS12390
uniprot id: V5SGB5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1029756:W911 RS16615
gene id: 1029756:W911_RS16615
uniprot id: V5SGQ3
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1029756:W911 RS02380
gene id: 1029756:W911_RS02380
uniprot id: V5SAR3
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1029756:W911 RS02825
gene id: 1029756:W911_RS02825
uniprot id: V5SAX2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

1029756:W911 RS08065
gene id: 1029756:W911_RS08065
uniprot id: V5SEL5
names: Similarity
messages: Belongs to the YkuD family.

1029756:W911 RS08380
gene id: 1029756:W911_RS08380
uniprot id: V5SEH1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1029756:W911 RS07765
gene id: 1029756:W911_RS07765
uniprot id: V5SBV3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1029756:W911 RS12705
gene id: 1029756:W911_RS12705
uniprot id: V5SF29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS10735
gene id: 1029756:W911_RS10735
uniprot id: V5SD81
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1029756:W911 RS14120
gene id: 1029756:W911_RS14120
uniprot id: M9SWI0
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.

1029756:W911 RS05270
gene id: 1029756:W911_RS05270
uniprot id: V5SBU1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1029756:W911 RS00450
gene id: 1029756:W911_RS00450
uniprot id: V5SB79
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1029756:W911 RS16445
gene id: 1029756:W911_RS16445
uniprot id: V5SI14
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1029756:W911 RS07220
gene id: 1029756:W911_RS07220
uniprot id: V5SCL0
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

1029756:W911 RS17165
gene id: 1029756:W911_RS17165
uniprot id: V5SAT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1029756:W911 RS13665
gene id: 1029756:W911_RS13665
uniprot id: V5SGZ0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1029756:W911 RS13770
gene id: 1029756:W911_RS13770
uniprot id: V5SHA7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1029756:W911 RS08045
gene id: 1029756:W911_RS08045
uniprot id: V5SJH8
names: Similarity
messages: Belongs to the intimin/invasin family.

1029756:W911 RS00520
gene id: 1029756:W911_RS00520
uniprot id: V5S8X8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1029756:W911 RS15325
gene id: 1029756:W911_RS15325
uniprot id: V5SHI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1029756:W911 RS08885
gene id: 1029756:W911_RS08885
uniprot id: V5SDG0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1029756:W911 RS03165
gene id: 1029756:W911_RS03165
uniprot id: V5SA77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1029756:W911 RS07485
gene id: 1029756:W911_RS07485
uniprot id: V5SE50
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1029756:W911 RS08120
gene id: 1029756:W911_RS08120
uniprot id: V5SD09
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

1029756:W911 RS03080
gene id: 1029756:W911_RS03080
uniprot id: V5SA66
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS10000
gene id: 1029756:W911_RS10000
uniprot id: V5SDU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecG subfamily.
messages: Cell inner membrane

1029756:W911 RS12375
gene id: 1029756:W911_RS12375
uniprot id: M9T4C2
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1029756:W911 RS09770
gene id: 1029756:W911_RS09770
uniprot id: V5SF33
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1029756:W911 RS06010
gene id: 1029756:W911_RS06010
uniprot id: V5SDN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1029756:W911 RS03050
gene id: 1029756:W911_RS03050
uniprot id: V5SA62
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1029756:W911 RS13680
gene id: 1029756:W911_RS13680
uniprot id: V5SFL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1029756:W911 RS15870
gene id: 1029756:W911_RS15870
uniprot id: V5SGI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1029756:W911 RS08550
gene id: 1029756:W911_RS08550
uniprot id: V5SD69
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1029756:W911 RS05020
gene id: 1029756:W911_RS05020
uniprot id: V5SBK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1029756:W911 RS12310
gene id: 1029756:W911_RS12310
uniprot id: V5SF00
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1029756:W911 RS03865
gene id: 1029756:W911_RS03865
uniprot id: V5SCJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1029756:W911 RS07185
gene id: 1029756:W911_RS07185
uniprot id: V5SCK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS09105
gene id: 1029756:W911_RS09105
uniprot id: V5SF27
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1029756:W911 RS06900
gene id: 1029756:W911_RS06900
uniprot id: V5SBB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1029756:W911 RS13670
gene id: 1029756:W911_RS13670
uniprot id: V5SEL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1029756:W911 RS04515
gene id: 1029756:W911_RS04515
uniprot id: V5SCT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1029756:W911 RS15550
gene id: 1029756:W911_RS15550
uniprot id: V5SHN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1029756:W911 RS15535
gene id: 1029756:W911_RS15535
uniprot id: V5SGD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1029756:W911 RS05325
gene id: 1029756:W911_RS05325
uniprot id: V5SBV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1029756:W911 RS10125
gene id: 1029756:W911_RS10125
uniprot id: V5SFA1
names: Similarity
messages: Belongs to the glutamine synthetase family.

1029756:W911 RS04650
gene id: 1029756:W911_RS04650
uniprot id: V5SD31
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1029756:W911 RS06155
gene id: 1029756:W911_RS06155
uniprot id: V5SHR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1029756:W911 RS10990
gene id: 1029756:W911_RS10990
uniprot id: V5SEE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

1029756:W911 RS11720
gene id: 1029756:W911_RS11720
uniprot id: V5SG94
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1029756:W911 RS05085
gene id: 1029756:W911_RS05085
uniprot id: V5SCY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

1029756:W911 RS11980
gene id: 1029756:W911_RS11980
uniprot id: V5SDR7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1029756:W911 RS09900
gene id: 1029756:W911_RS09900
uniprot id: V5SFE7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1029756:W911 RS05525
gene id: 1029756:W911_RS05525
uniprot id: V5SD60
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1029756:W911 RS11405
gene id: 1029756:W911_RS11405
uniprot id: V5SEK3
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1029756:W911 RS08730
gene id: 1029756:W911_RS08730
uniprot id: V5SC93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS09375
gene id: 1029756:W911_RS09375
uniprot id: V5SCI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cytoplasm
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1029756:W911 RS16215
gene id: 1029756:W911_RS16215
uniprot id: V5SHZ0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1029756:W911 RS15100
gene id: 1029756:W911_RS15100
uniprot id: V5SG22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1029756:W911 RS16165
gene id: 1029756:W911_RS16165
uniprot id: V5SGJ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1029756:W911 RS08265
gene id: 1029756:W911_RS08265
uniprot id: V5SEP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1029756:W911 RS06350
gene id: 1029756:W911_RS06350
uniprot id: V5SC62
names: Similarity
messages: Belongs to the cytochrome P450 family.

1029756:W911 RS08205
gene id: 1029756:W911_RS08205
uniprot id: V5SD59
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS12235
gene id: 1029756:W911_RS12235
uniprot id: V5SG88
names: Similarity
messages: Belongs to the ros/MucR family.

1029756:W911 RS01530
gene id: 1029756:W911_RS01530
uniprot id: V5SBH4
names: Similarity
messages: Belongs to the thioredoxin family.

1029756:W911 RS08165
gene id: 1029756:W911_RS08165
uniprot id: V5SEN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1029756:W911 RS01030
gene id: 1029756:W911_RS01030
uniprot id: V5SBB6
names: Function
names: Similarity
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.

1029756:W911 RS11475
gene id: 1029756:W911_RS11475
uniprot id: V5SEI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1029756:W911 RS12825
gene id: 1029756:W911_RS12825
uniprot id: V5SF51
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1029756:W911 RS02920
gene id: 1029756:W911_RS02920
uniprot id: V5SCB0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1029756:W911 RS07910
gene id: 1029756:W911_RS07910
uniprot id: V5SE99
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS10525
gene id: 1029756:W911_RS10525
uniprot id: V5SD27
names: Similarity
messages: Belongs to the pirin family.

1029756:W911 RS01415
gene id: 1029756:W911_RS01415
uniprot id: V5SBG2
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS06725
gene id: 1029756:W911_RS06725
uniprot id: V5SB95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1029756:W911 RS09930
gene id: 1029756:W911_RS09930
uniprot id: V5SFF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1029756:W911 RS09110
gene id: 1029756:W911_RS09110
uniprot id: V5SET1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1029756:W911 RS10740
gene id: 1029756:W911_RS10740
uniprot id: V5SEB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1029756:W911 RS08565
gene id: 1029756:W911_RS08565
uniprot id: V5SGX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1029756:W911 RS00455
gene id: 1029756:W911_RS00455
uniprot id: V5SAG1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1029756:W911 RS12295
gene id: 1029756:W911_RS12295
uniprot id: V5SEW5
names: Similarity
messages: Belongs to the CutA family.

1029756:W911 RS09980
gene id: 1029756:W911_RS09980
uniprot id: V5SCR7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1029756:W911 RS14655
gene id: 1029756:W911_RS14655
uniprot id: V5SEX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1029756:W911 RS10940
gene id: 1029756:W911_RS10940
uniprot id: V5SDB4
names: Similarity
messages: Belongs to the YicC/YloC family.

1029756:W911 RS15500
gene id: 1029756:W911_RS15500
uniprot id: V5SHM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1029756:W911 RS05745
gene id: 1029756:W911_RS05745
uniprot id: V5SDK6
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1029756:W911 RS05220
gene id: 1029756:W911_RS05220
uniprot id: V5SAV8
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS15665
gene id: 1029756:W911_RS15665
uniprot id: V5SGF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1029756:W911 RS10790
gene id: 1029756:W911_RS10790
uniprot id: V5SFM9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1029756:W911 RS02955
gene id: 1029756:W911_RS02955
uniprot id: V5SCB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS02255
gene id: 1029756:W911_RS02255
uniprot id: V5SAN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1029756:W911 RS13235
gene id: 1029756:W911_RS13235
uniprot id: V5SFC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1029756:W911 RS02965
gene id: 1029756:W911_RS02965
uniprot id: V5SA46
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

1029756:W911 RS01945
gene id: 1029756:W911_RS01945
uniprot id: V5S9Z3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS14340
gene id: 1029756:W911_RS14340
uniprot id: V5SES7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1029756:W911 RS16070
gene id: 1029756:W911_RS16070
uniprot id: V5SI78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1029756:W911 RS00895
gene id: 1029756:W911_RS00895
uniprot id: V5S964
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1029756:W911 RS06060
gene id: 1029756:W911_RS06060
uniprot id: V5SC61
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1029756:W911 RS10355
gene id: 1029756:W911_RS10355
uniprot id: V5SCX3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1029756:W911 RS02860
gene id: 1029756:W911_RS02860
uniprot id: V5SAX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1029756:W911 RS16680
gene id: 1029756:W911_RS16680
uniprot id: V5SFQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1029756:W911 RS04865
gene id: 1029756:W911_RS04865
uniprot id: V5SBH7
names: Similarity
messages: Belongs to the Dps family.

1029756:W911 RS13400
gene id: 1029756:W911_RS13400
uniprot id: V5SFH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS00595
gene id: 1029756:W911_RS00595
uniprot id: V5SAI8
names: Similarity
messages: Belongs to the BolA/IbaG family.

1029756:W911 RS10810
gene id: 1029756:W911_RS10810
uniprot id: V5SE95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1029756:W911 RS10095
gene id: 1029756:W911_RS10095
uniprot id: V5SFH6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1029756:W911 RS07380
gene id: 1029756:W911_RS07380
uniprot id: V5SE20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1029756:W911 RS06925
gene id: 1029756:W911_RS06925
uniprot id: V5SDR8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1029756:W911 RS11950
gene id: 1029756:W911_RS11950
uniprot id: V5SET7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1029756:W911 RS07070
gene id: 1029756:W911_RS07070
uniprot id: V5SE38
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1029756:W911 RS02745
gene id: 1029756:W911_RS02745
uniprot id: V5SA13
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS04440
gene id: 1029756:W911_RS04440
uniprot id: V5SBD9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1029756:W911 RS13645
gene id: 1029756:W911_RS13645
uniprot id: V5SEK7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1029756:W911 RS04875
gene id: 1029756:W911_RS04875
uniprot id: V5SCV8
names: Similarity
messages: Belongs to the universal stress protein A family.

1029756:W911 RS16660
gene id: 1029756:W911_RS16660
uniprot id: V5SGU6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1029756:W911 RS13035
gene id: 1029756:W911_RS13035
uniprot id: V5SFB3
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1029756:W911 RS01270
gene id: 1029756:W911_RS01270
uniprot id: V5SBE2
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS15050
gene id: 1029756:W911_RS15050
uniprot id: V5SHQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1029756:W911 RS13355
gene id: 1029756:W911_RS13355
uniprot id: V5SH03
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1029756:W911 RS06370
gene id: 1029756:W911_RS06370
uniprot id: V5SCA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1029756:W911 RS15910
gene id: 1029756:W911_RS15910
uniprot id: V5SI48
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1029756:W911 RS03130
gene id: 1029756:W911_RS03130
uniprot id: V5SCE5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS06335
gene id: 1029756:W911_RS06335
uniprot id: V5SB70
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1029756:W911 RS00030
gene id: 1029756:W911_RS00030
uniprot id: V5SAA3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1029756:W911 RS15590
gene id: 1029756:W911_RS15590
uniprot id: V5SGB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1029756:W911 RS16635
gene id: 1029756:W911_RS16635
uniprot id: V5SGU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1029756:W911 RS00690
gene id: 1029756:W911_RS00690
uniprot id: V5SAK0
names: Similarity
messages: Belongs to the SCO1/2 family.

1029756:W911 RS10590
gene id: 1029756:W911_RS10590
uniprot id: V5SE62
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1029756:W911 RS01840
gene id: 1029756:W911_RS01840
uniprot id: V5S9L4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1029756:W911 RS15365
gene id: 1029756:W911_RS15365
uniprot id: V5SHJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1029756:W911 RS10745
gene id: 1029756:W911_RS10745
uniprot id: V5SE85
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS13765
gene id: 1029756:W911_RS13765
uniprot id: V5SFM0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1029756:W911 RS02345
gene id: 1029756:W911_RS02345
uniprot id: V5S9U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1029756:W911 RS05000
gene id: 1029756:W911_RS05000
uniprot id: V5SD72
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1029756:W911 RS03790
gene id: 1029756:W911_RS03790
uniprot id: V5SB65
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1029756:W911 RS16570
gene id: 1029756:W911_RS16570
uniprot id: V5SGT1
names: Similarity
messages: Belongs to the hyi family.

1029756:W911 RS00070
gene id: 1029756:W911_RS00070
uniprot id: V5S947
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1029756:W911 RS03870
gene id: 1029756:W911_RS03870
uniprot id: V5SAG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1029756:W911 RS05605
gene id: 1029756:W911_RS05605
uniprot id: V5SDI8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1029756:W911 RS01315
gene id: 1029756:W911_RS01315
uniprot id: V5S9Q3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1029756:W911 RS02660
gene id: 1029756:W911_RS02660
uniprot id: V5SAV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1029756:W911 RS02900
gene id: 1029756:W911_RS02900
uniprot id: V5SC51
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1029756:W911 RS01325
gene id: 1029756:W911_RS01325
uniprot id: V5SBE8
names: Similarity
messages: Belongs to the CmpA/NrtA family.

1029756:W911 RS10270
gene id: 1029756:W911_RS10270
uniprot id: V5SDZ3
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS13585
gene id: 1029756:W911_RS13585
uniprot id: V5SH40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1029756:W911 RS11200
gene id: 1029756:W911_RS11200
uniprot id: V5SFT6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1029756:W911 RS04080
gene id: 1029756:W911_RS04080
uniprot id: V5SGD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1029756:W911 RS15945
gene id: 1029756:W911_RS15945
uniprot id: V5SFG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS04010
gene id: 1029756:W911_RS04010
uniprot id: V5SAT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1029756:W911 RS13165
gene id: 1029756:W911_RS13165
uniprot id: V5SFB1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1029756:W911 RS10825
gene id: 1029756:W911_RS10825
uniprot id: V5SD96
names: Similarity
messages: Belongs to the TrpC family.

1029756:W911 RS13755
gene id: 1029756:W911_RS13755
uniprot id: V5SEM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1029756:W911 RS15930
gene id: 1029756:W911_RS15930
uniprot id: V5SGG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1029756:W911 RS11355
gene id: 1029756:W911_RS11355
uniprot id: V5SEG8
names: Similarity
messages: Belongs to the BolA/IbaG family.

1029756:W911 RS03995
gene id: 1029756:W911_RS03995
uniprot id: V5SCM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1029756:W911 RS07560
gene id: 1029756:W911_RS07560
uniprot id: V5SE57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1029756:W911 RS09675
gene id: 1029756:W911_RS09675
uniprot id: V5SF19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1029756:W911 RS14525
gene id: 1029756:W911_RS14525
uniprot id: V5SFT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1029756:W911 RS10670
gene id: 1029756:W911_RS10670
uniprot id: V5SE74
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1029756:W911 RS13550
gene id: 1029756:W911_RS13550
uniprot id: V5SFJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1029756:W911 RS02960
gene id: 1029756:W911_RS02960
uniprot id: V5SC60
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1029756:W911 RS02205
gene id: 1029756:W911_RS02205
uniprot id: V5SA28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1029756:W911 RS16200
gene id: 1029756:W911_RS16200
uniprot id: V5SGK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1029756:W911 RS09815
gene id: 1029756:W911_RS09815
uniprot id: V5SDV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1029756:W911 RS14330
gene id: 1029756:W911_RS14330
uniprot id: V5SHF0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1029756:W911 RS09205
gene id: 1029756:W911_RS09205
uniprot id: V5SF40
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

1029756:W911 RS03860
gene id: 1029756:W911_RS03860
uniprot id: V5SCP7
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1029756:W911 RS00800
gene id: 1029756:W911_RS00800
uniprot id: V5S9F4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1029756:W911 RS05445
gene id: 1029756:W911_RS05445
uniprot id: V5SD46
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1029756:W911 RS09830
gene id: 1029756:W911_RS09830
uniprot id: V5SF46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1029756:W911 RS10145
gene id: 1029756:W911_RS10145
uniprot id: V5SFI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1029756:W911 RS12430
gene id: 1029756:W911_RS12430
uniprot id: V5SGK8
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS09825
gene id: 1029756:W911_RS09825
uniprot id: V5SFD3
names: Similarity
messages: Belongs to the Gfa family.

1029756:W911 RS10575
gene id: 1029756:W911_RS10575
uniprot id: V5SD43
names: Similarity
messages: Belongs to the Dps family.

1029756:W911 RS13610
gene id: 1029756:W911_RS13610
uniprot id: V5SH46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1029756:W911 RS11635
gene id: 1029756:W911_RS11635
uniprot id: V5SFZ8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1029756:W911 RS08140
gene id: 1029756:W911_RS08140
uniprot id: V5SEC9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

1029756:W911 RS09020
gene id: 1029756:W911_RS09020
uniprot id: V5SDE2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1029756:W911 RS16585
gene id: 1029756:W911_RS16585
uniprot id: V5SID3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1029756:W911 RS02240
gene id: 1029756:W911_RS02240
uniprot id: V5SBT9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1029756:W911 RS10255
gene id: 1029756:W911_RS10255
uniprot id: V5SFC4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS07190
gene id: 1029756:W911_RS07190
uniprot id: V5SE60
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1029756:W911 RS07935
gene id: 1029756:W911_RS07935
uniprot id: V5SEA3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1029756:W911 RS13495
gene id: 1029756:W911_RS13495
uniprot id: V5SH25
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1029756:W911 RS16510
gene id: 1029756:W911_RS16510
uniprot id: V5SI27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1029756:W911 RS01260
gene id: 1029756:W911_RS01260
uniprot id: V5SBK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1029756:W911 RS07970
gene id: 1029756:W911_RS07970
uniprot id: V5SBY3
names: Subcellular Location Annotation
messages: Cytoplasm

1029756:W911 RS15080
gene id: 1029756:W911_RS15080
uniprot id: V5SHR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1029756:W911 RS15420
gene id: 1029756:W911_RS15420
uniprot id: V5SF87
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

1029756:W911 RS13580
gene id: 1029756:W911_RS13580
uniprot id: V5SFI2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1029756:W911 RS13115
gene id: 1029756:W911_RS13115
uniprot id: V5SGN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1029756:W911 RS01045
gene id: 1029756:W911_RS01045
uniprot id: V5SA63
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1029756:W911 RS07555
gene id: 1029756:W911_RS07555
uniprot id: V5SEF2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1029756:W911 RS08595
gene id: 1029756:W911_RS08595
uniprot id: V5SC74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1029756:W911 RS04530
gene id: 1029756:W911_RS04530
uniprot id: V5SBF0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1029756:W911 RS05385
gene id: 1029756:W911_RS05385
uniprot id: V5SBR6
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1029756:W911 RS00790
gene id: 1029756:W911_RS00790
uniprot id: V5S929
names: Similarity
messages: Belongs to the YciI family.

1029756:W911 RS04250
gene id: 1029756:W911_RS04250
uniprot id: V5SCR3
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1029756:W911 RS14740
gene id: 1029756:W911_RS14740
uniprot id: V5SFW6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1029756:W911 RS07535
gene id: 1029756:W911_RS07535
uniprot id: V5SCW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.
messages: Membrane

1029756:W911 RS13260
gene id: 1029756:W911_RS13260
uniprot id: V5SFC6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS11800
gene id: 1029756:W911_RS11800
uniprot id: V5SER2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1029756:W911 RS10360
gene id: 1029756:W911_RS10360
uniprot id: V5SE35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1029756:W911 RS12455
gene id: 1029756:W911_RS12455
uniprot id: V5SGL3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1029756:W911 RS11055
gene id: 1029756:W911_RS11055
uniprot id: V5SFR9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1029756:W911 RS12240
gene id: 1029756:W911_RS12240
uniprot id: V5SDW2
names: Similarity
messages: Belongs to the peptidase S9A family.

1029756:W911 RS01965
gene id: 1029756:W911_RS01965
uniprot id: V5SAI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1029756:W911 RS04545
gene id: 1029756:W911_RS04545
uniprot id: V5SAR4
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS15885
gene id: 1029756:W911_RS15885
uniprot id: V5SHT4
names: Similarity
messages: Belongs to the peptidase M24B family.

1029756:W911 RS02815
gene id: 1029756:W911_RS02815
uniprot id: V5SC34
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1029756:W911 RS14725
gene id: 1029756:W911_RS14725
uniprot id: V5SEY5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1029756:W911 RS13950
gene id: 1029756:W911_RS13950
uniprot id: V5SH12
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1029756:W911 RS15950
gene id: 1029756:W911_RS15950
uniprot id: V5SGJ8
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS12045
gene id: 1029756:W911_RS12045
uniprot id: V5SDS9
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1029756:W911 RS16830
gene id: 1029756:W911_RS16830
uniprot id: V5SIH4
names: Caution
names: Similarity
messages: Belongs to the UPF0391 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS11195
gene id: 1029756:W911_RS11195
uniprot id: V5SG17
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1029756:W911 RS02245
gene id: 1029756:W911_RS02245
uniprot id: V5S9T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1029756:W911 RS06075
gene id: 1029756:W911_RS06075
uniprot id: V5SDD8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1029756:W911 RS10570
gene id: 1029756:W911_RS10570
uniprot id: V5SFI5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS16755
gene id: 1029756:W911_RS16755
uniprot id: V5SFR7
names: Similarity
messages: Belongs to the peptidase S49 family.

1029756:W911 RS09865
gene id: 1029756:W911_RS09865
uniprot id: V5SDV9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS13040
gene id: 1029756:W911_RS13040
uniprot id: V5SF90
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1029756:W911 RS14040
gene id: 1029756:W911_RS14040
uniprot id: V5SIM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1029756:W911 RS05570
gene id: 1029756:W911_RS05570
uniprot id: V5SDI3
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1029756:W911 RS12440
gene id: 1029756:W911_RS12440
uniprot id: V5SDZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS08590
gene id: 1029756:W911_RS08590
uniprot id: V5SEK4
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

1029756:W911 RS10435
gene id: 1029756:W911_RS10435
uniprot id: V5SCZ0
names: Similarity
messages: Belongs to the GARS family.

1029756:W911 RS09270
gene id: 1029756:W911_RS09270
uniprot id: V5SEV7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS05280
gene id: 1029756:W911_RS05280
uniprot id: V5SDC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1029756:W911 RS15385
gene id: 1029756:W911_RS15385
uniprot id: V5SHW0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1029756:W911 RS01735
gene id: 1029756:W911_RS01735
uniprot id: V5SBK0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1029756:W911 RS08200
gene id: 1029756:W911_RS08200
uniprot id: V5SC13
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1029756:W911 RS10920
gene id: 1029756:W911_RS10920
uniprot id: V5SED4
names: Similarity
messages: Belongs to the GcvT family.

1029756:W911 RS11380
gene id: 1029756:W911_RS11380
uniprot id: V5SEJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1029756:W911 RS09195
gene id: 1029756:W911_RS09195
uniprot id: V5SDK7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS08500
gene id: 1029756:W911_RS08500
uniprot id: V5SDA7
names: Subcellular Location Annotation
messages: Cytoplasm

1029756:W911 RS03805
gene id: 1029756:W911_RS03805
uniprot id: V5SCI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1029756:W911 RS00725
gene id: 1029756:W911_RS00725
uniprot id: V5SAK4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1029756:W911 RS07285
gene id: 1029756:W911_RS07285
uniprot id: V5SBI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1029756:W911 RS07640
gene id: 1029756:W911_RS07640
uniprot id: V5SEG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. FixP subunit is required for transferring electrons from donor cytochrome c via its heme groups to FixO subunit. From there, electrons are shuttled to the catalytic binuclear center of FixN subunit where oxygen reduction takes place. The complex also functions as a proton pump.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase at least composed of FixN, FixO, FixQ and FixP.
messages: Membrane

1029756:W911 RS09185
gene id: 1029756:W911_RS09185
uniprot id: V5SEU1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1029756:W911 RS10515
gene id: 1029756:W911_RS10515
uniprot id: V5SFH2
names: Similarity
messages: Belongs to the amidase family.

1029756:W911 RS00460
gene id: 1029756:W911_RS00460
uniprot id: V5S8X0
names: Similarity
messages: Belongs to the asparagine synthetase family.

1029756:W911 RS01830
gene id: 1029756:W911_RS01830
uniprot id: V5SBS9
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1029756:W911 RS05185
gene id: 1029756:W911_RS05185
uniprot id: V5SD01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

1029756:W911 RS05600
gene id: 1029756:W911_RS05600
uniprot id: V5SBV7
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

1029756:W911 RS06475
gene id: 1029756:W911_RS06475
uniprot id: V5SB80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1029756:W911 RS07865
gene id: 1029756:W911_RS07865
uniprot id: V5SD11
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1029756:W911 RS10230
gene id: 1029756:W911_RS10230
uniprot id: V5SE19
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1029756:W911 RS09545
gene id: 1029756:W911_RS09545
uniprot id: V5SDR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS10585
gene id: 1029756:W911_RS10585
uniprot id: V5SE88
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1029756:W911 RS05035
gene id: 1029756:W911_RS05035
uniprot id: V5SAT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

1029756:W911 RS13640
gene id: 1029756:W911_RS13640
uniprot id: V5SGY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1029756:W911 RS02285
gene id: 1029756:W911_RS02285
uniprot id: V5S9U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1029756:W911 RS08030
gene id: 1029756:W911_RS08030
uniprot id: V5SCZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

1029756:W911 RS09690
gene id: 1029756:W911_RS09690
uniprot id: V5SDP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1029756:W911 RS07305
gene id: 1029756:W911_RS07305
uniprot id: V5SDZ7
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

1029756:W911 RS10830
gene id: 1029756:W911_RS10830
uniprot id: V5SEC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1029756:W911 RS16650
gene id: 1029756:W911_RS16650
uniprot id: V5SI47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1029756:W911 RS01920
gene id: 1029756:W911_RS01920
uniprot id: V5SBN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1029756:W911 RS16875
gene id: 1029756:W911_RS16875
uniprot id: V5SGV5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1029756:W911 RS15360
gene id: 1029756:W911_RS15360
uniprot id: V5SHV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1029756:W911 RS12750
gene id: 1029756:W911_RS12750
uniprot id: V5SGH4
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1029756:W911 RS14910
gene id: 1029756:W911_RS14910
uniprot id: V5SFZ2
names: Similarity
messages: Belongs to the pyruvate kinase family.

1029756:W911 RS03970
gene id: 1029756:W911_RS03970
uniprot id: V5SCM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1029756:W911 RS00010
gene id: 1029756:W911_RS00010
uniprot id: V5S8Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1029756:W911 RS11955
gene id: 1029756:W911_RS11955
uniprot id: V5SER0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1029756:W911 RS02310
gene id: 1029756:W911_RS02310
uniprot id: V5SC10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1029756:W911 RS06325
gene id: 1029756:W911_RS06325
uniprot id: V5SDI0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1029756:W911 RS08195
gene id: 1029756:W911_RS08195
uniprot id: V5SEE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1029756:W911 RS06360
gene id: 1029756:W911_RS06360
uniprot id: V5SDI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1029756:W911 RS03945
gene id: 1029756:W911_RS03945
uniprot id: V5SCL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1029756:W911 RS02675
gene id: 1029756:W911_RS02675
uniprot id: V5SC14
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1029756:W911 RS07125
gene id: 1029756:W911_RS07125
uniprot id: V5SBF4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS11090
gene id: 1029756:W911_RS11090
uniprot id: V5SG04
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1029756:W911 RS04215
gene id: 1029756:W911_RS04215
uniprot id: V5SBC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1029756:W911 RS10685
gene id: 1029756:W911_RS10685
uniprot id: V5SD70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1029756:W911 RS01190
gene id: 1029756:W911_RS01190
uniprot id: V5SA88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1029756:W911 RS15110
gene id: 1029756:W911_RS15110
uniprot id: V5SHF3
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1029756:W911 RS03675
gene id: 1029756:W911_RS03675
uniprot id: V5SB47
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1029756:W911 RS10005
gene id: 1029756:W911_RS10005
uniprot id: V5SFG0
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1029756:W911 RS11360
gene id: 1029756:W911_RS11360
uniprot id: V5SG39
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1029756:W911 RS03075
gene id: 1029756:W911_RS03075
uniprot id: V5SC81
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1029756:W911 RS10240
gene id: 1029756:W911_RS10240
uniprot id: V5SFJ6
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1029756:W911 RS17585
gene id: 1029756:W911_RS17585
uniprot id: V5SGM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1029756:W911 RS13695
gene id: 1029756:W911_RS13695
uniprot id: V5SEL8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1029756:W911 RS12935
gene id: 1029756:W911_RS12935
uniprot id: V5SF98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FTR family.
messages: Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT).
messages: Cytoplasm
messages: Homotetramer.

1029756:W911 RS16760
gene id: 1029756:W911_RS16760
uniprot id: V5SGW8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1029756:W911 RS12465
gene id: 1029756:W911_RS12465
uniprot id: V5SDZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1029756:W911 RS06970
gene id: 1029756:W911_RS06970
uniprot id: V5SE21
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1029756:W911 RS15680
gene id: 1029756:W911_RS15680
uniprot id: V5SHQ2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1029756:W911 RS13600
gene id: 1029756:W911_RS13600
uniprot id: V5SFJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1029756:W911 RS00840
gene id: 1029756:W911_RS00840
uniprot id: V5SAM5
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1029756:W911 RS15030
gene id: 1029756:W911_RS15030
uniprot id: V5SF32
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1029756:W911 RS13715
gene id: 1029756:W911_RS13715
uniprot id: V5SH97
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS14880
gene id: 1029756:W911_RS14880
uniprot id: V5SG21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS12065
gene id: 1029756:W911_RS12065
uniprot id: V5SG61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

1029756:W911 RS09035
gene id: 1029756:W911_RS09035
uniprot id: V5SER9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1029756:W911 RS15705
gene id: 1029756:W911_RS15705
uniprot id: V5SHQ9
names: Similarity
messages: Belongs to the GPI family.

1029756:W911 RS09130
gene id: 1029756:W911_RS09130
uniprot id: V5SF31
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1029756:W911 RS06040
gene id: 1029756:W911_RS06040
uniprot id: V5SDP0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1029756:W911 RS15880
gene id: 1029756:W911_RS15880
uniprot id: V5SI44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1029756:W911 RS06105
gene id: 1029756:W911_RS06105
uniprot id: V5SB44
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1029756:W911 RS05120
gene id: 1029756:W911_RS05120
uniprot id: V5SBR1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1029756:W911 RS15320
gene id: 1029756:W911_RS15320
uniprot id: V5SHV0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1029756:W911 RS01200
gene id: 1029756:W911_RS01200
uniprot id: V5SBJ9
names: Subcellular Location Annotation
messages: Nucleus

1029756:W911 RS13110
gene id: 1029756:W911_RS13110
uniprot id: V5SGW6
names: Similarity
messages: Belongs to the LOG family.

1029756:W911 RS07430
gene id: 1029756:W911_RS07430
uniprot id: V5SCR9
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1029756:W911 RS08525
gene id: 1029756:W911_RS08525
uniprot id: V5SC64
names: Similarity
messages: Belongs to the RecJ family.

1029756:W911 RS05295
gene id: 1029756:W911_RS05295
uniprot id: V5SBU5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1029756:W911 RS02740
gene id: 1029756:W911_RS02740
uniprot id: V5SC24
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1029756:W911 RS06575
gene id: 1029756:W911_RS06575
uniprot id: V5SDX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1029756:W911 RS09275
gene id: 1029756:W911_RS09275
uniprot id: V5SCH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1029756:W911 RS08050
gene id: 1029756:W911_RS08050
uniprot id: V5SBZ0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1029756:W911 RS01105
gene id: 1029756:W911_RS01105
uniprot id: V5S9A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1029756:W911 RS05870
gene id: 1029756:W911_RS05870
uniprot id: V5SDB3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1029756:W911 RS00405
gene id: 1029756:W911_RS00405
uniprot id: V5SAF5
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1029756:W911 RS10300
gene id: 1029756:W911_RS10300
uniprot id: V5SDZ8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1029756:W911 RS14530
gene id: 1029756:W911_RS14530
uniprot id: V5SHH6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS08475
gene id: 1029756:W911_RS08475
uniprot id: V5SDA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

1029756:W911 RS04165
gene id: 1029756:W911_RS04165
uniprot id: V5SBB8
names: Similarity
messages: Belongs to the YkuD family.

1029756:W911 RS05055
gene id: 1029756:W911_RS05055
uniprot id: V5SD80
names: Similarity
messages: Belongs to the ArsC family.

1029756:W911 RS01685
gene id: 1029756:W911_RS01685
uniprot id: V5SBJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1029756:W911 RS11235
gene id: 1029756:W911_RS11235
uniprot id: V5SEI0
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS16205
gene id: 1029756:W911_RS16205
uniprot id: V5SI93
names: Similarity
messages: Belongs to the histone deacetylase family.

1029756:W911 RS09510
gene id: 1029756:W911_RS09510
uniprot id: V5SI40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1029756:W911 RS00730
gene id: 1029756:W911_RS00730
uniprot id: V5S917
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1029756:W911 RS09940
gene id: 1029756:W911_RS09940
uniprot id: V5SCR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1029756:W911 RS08935
gene id: 1029756:W911_RS08935
uniprot id: V5SEZ8
names: Similarity
messages: Belongs to the SfsA family.

1029756:W911 RS00205
gene id: 1029756:W911_RS00205
uniprot id: V5S9N4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1029756:W911 RS14835
gene id: 1029756:W911_RS14835
uniprot id: V5SFY1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1029756:W911 RS04425
gene id: 1029756:W911_RS04425
uniprot id: V5SBH9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1029756:W911 RS09290
gene id: 1029756:W911_RS09290
uniprot id: V5SF54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1029756:W911 RS15190
gene id: 1029756:W911_RS15190
uniprot id: V5SHT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1029756:W911 RS16805
gene id: 1029756:W911_RS16805
uniprot id: V5SIH0
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1029756:W911 RS02390
gene id: 1029756:W911_RS02390
uniprot id: V5SC27
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1029756:W911 RS05620
gene id: 1029756:W911_RS05620
uniprot id: V5SC06
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1029756:W911 RS10040
gene id: 1029756:W911_RS10040
uniprot id: V5SF86
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1029756:W911 RS12995
gene id: 1029756:W911_RS12995
uniprot id: V5SE63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

1029756:W911 RS03230
gene id: 1029756:W911_RS03230
uniprot id: V5SCG2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1029756:W911 RS10370
gene id: 1029756:W911_RS10370
uniprot id: V5SFL4
names: Similarity
messages: Belongs to the YkuD family.

1029756:W911 RS06840
gene id: 1029756:W911_RS06840
uniprot id: V5SDQ4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1029756:W911 RS10415
gene id: 1029756:W911_RS10415
uniprot id: V5SE44
names: Function
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1029756:W911 RS15505
gene id: 1029756:W911_RS15505
uniprot id: V5SFA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

1029756:W911 RS04920
gene id: 1029756:W911_RS04920
uniprot id: V5SBM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1029756:W911 RS13455
gene id: 1029756:W911_RS13455
uniprot id: V5SED6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1029756:W911 RS15135
gene id: 1029756:W911_RS15135
uniprot id: V5SHF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1029756:W911 RS03160
gene id: 1029756:W911_RS03160
uniprot id: V5SC97
names: Similarity
messages: Belongs to the aspartokinase family.

1029756:W911 RS03295
gene id: 1029756:W911_RS03295
uniprot id: V5SCB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1029756:W911 RS09220
gene id: 1029756:W911_RS09220
uniprot id: V5SDL2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1029756:W911 RS15440
gene id: 1029756:W911_RS15440
uniprot id: V5SHL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1029756:W911 RS02520
gene id: 1029756:W911_RS02520
uniprot id: V5SC47
names: Cofactor
messages: Binds 1 copper ion per subunit.

1029756:W911 RS12425
gene id: 1029756:W911_RS12425
uniprot id: V5SEY6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1029756:W911 RS04445
gene id: 1029756:W911_RS04445
uniprot id: V5SD16
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1029756:W911 RS07860
gene id: 1029756:W911_RS07860
uniprot id: V5SBW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1029756:W911 RS14485
gene id: 1029756:W911_RS14485
uniprot id: V5SEU9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1029756:W911 RS06915
gene id: 1029756:W911_RS06915
uniprot id: V5SCE7
names: Function
messages: Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A.

1029756:W911 RS18790
gene id: 1029756:W911_RS18790
uniprot id: V5SGR8
names: Similarity
messages: Belongs to the HisA/HisF family.

1029756:W911 RS04895
gene id: 1029756:W911_RS04895
uniprot id: V5SGJ3
names: Similarity
messages: Belongs to the AHA1 family.

1029756:W911 RS10960
gene id: 1029756:W911_RS10960
uniprot id: V5SFY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1029756:W911 RS07895
gene id: 1029756:W911_RS07895
uniprot id: V5SD14
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1029756:W911 RS08845
gene id: 1029756:W911_RS08845
uniprot id: V5SDB5
names: Similarity
messages: Belongs to the peptidase C56 family.

1029756:W911 RS13630
gene id: 1029756:W911_RS13630
uniprot id: V5SFK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1029756:W911 RS02515
gene id: 1029756:W911_RS02515
uniprot id: V5SA69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aromatic amine dehydrogenase light chain family.
messages: Heterotetramer of two light and two heavy chains.
messages: Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin.
messages: Periplasm

1029756:W911 RS16145
gene id: 1029756:W911_RS16145
uniprot id: V5SFJ2
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1029756:W911 RS11010
gene id: 1029756:W911_RS11010
uniprot id: V5SDC4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1029756:W911 RS13690
gene id: 1029756:W911_RS13690
uniprot id: V5SGZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1029756:W911 RS04210
gene id: 1029756:W911_RS04210
uniprot id: V5SBF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1029756:W911 RS08025
gene id: 1029756:W911_RS08025
uniprot id: V5SD33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1029756:W911 RS12885
gene id: 1029756:W911_RS12885
uniprot id: V5SGT2
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.

1029756:W911 RS04000
gene id: 1029756:W911_RS04000
uniprot id: V5SAJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1029756:W911 RS13750
gene id: 1029756:W911_RS13750
uniprot id: V5SH02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1029756:W911 RS05490
gene id: 1029756:W911_RS05490
uniprot id: V5SBT7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1029756:W911 RS14475
gene id: 1029756:W911_RS14475
uniprot id: V5SH61
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.
messages: Hydrolyzes indole-3-acetamide (IAM) into indole-3-acetic acid (IAA).

1029756:W911 RS03320
gene id: 1029756:W911_RS03320
uniprot id: V5SCC1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1029756:W911 RS14325
gene id: 1029756:W911_RS14325
uniprot id: V5SFQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1029756:W911 RS09965
gene id: 1029756:W911_RS09965
uniprot id: V5SF75
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS01825
gene id: 1029756:W911_RS01825
uniprot id: V5S9X5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1029756:W911 RS06080
gene id: 1029756:W911_RS06080
uniprot id: V5SB41
names: Similarity
messages: Belongs to the universal stress protein A family.

1029756:W911 RS04795
gene id: 1029756:W911_RS04795
uniprot id: V5SAS7
names: Similarity
messages: Belongs to the PqqA family.

1029756:W911 RS14585
gene id: 1029756:W911_RS14585
uniprot id: V5SHI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1029756:W911 RS09210
gene id: 1029756:W911_RS09210
uniprot id: V5SEU6
names: Similarity
messages: Belongs to the HesB/IscA family.

1029756:W911 RS09265
gene id: 1029756:W911_RS09265
uniprot id: V5SF48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1029756:W911 RS04975
gene id: 1029756:W911_RS04975
uniprot id: V5SCW9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1029756:W911 RS11730
gene id: 1029756:W911_RS11730
uniprot id: V5SDM9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1029756:W911 RS07615
gene id: 1029756:W911_RS07615
uniprot id: V5SEG1
names: Similarity
messages: Belongs to the universal stress protein A family.

1029756:W911 RS02070
gene id: 1029756:W911_RS02070
uniprot id: V5SBW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1029756:W911 RS10800
gene id: 1029756:W911_RS10800
uniprot id: V5SEB8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1029756:W911 RS05700
gene id: 1029756:W911_RS05700
uniprot id: V5SC15
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1029756:W911 RS07470
gene id: 1029756:W911_RS07470
uniprot id: V5SCW0
names: Similarity
messages: Belongs to the GST superfamily.

1029756:W911 RS11040
gene id: 1029756:W911_RS11040
uniprot id: V5SEF6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1029756:W911 RS10710
gene id: 1029756:W911_RS10710
uniprot id: V5SD77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1029756:W911 RS10820
gene id: 1029756:W911_RS10820
uniprot id: V5SFN5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS02315
gene id: 1029756:W911_RS02315
uniprot id: V5SBV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1029756:W911 RS10835
gene id: 1029756:W911_RS10835
uniprot id: V5SE98
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1029756:W911 RS16980
gene id: 1029756:W911_RS16980
uniprot id: V5SIA2
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1029756:W911 RS02130
gene id: 1029756:W911_RS02130
uniprot id: V5SBR8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1029756:W911 RS09455
gene id: 1029756:W911_RS09455
uniprot id: V5SEY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

1029756:W911 RS16715
gene id: 1029756:W911_RS16715
uniprot id: V5SGS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1029756:W911 RS11300
gene id: 1029756:W911_RS11300
uniprot id: V5SEI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1029756:W911 RS16740
gene id: 1029756:W911_RS16740
uniprot id: V5SGS9
names: Similarity
messages: Belongs to the TrpF family.

1029756:W911 RS13220
gene id: 1029756:W911_RS13220
uniprot id: V5SE97
names: Similarity
messages: Belongs to the TPP enzyme family.

1029756:W911 RS00855
gene id: 1029756:W911_RS00855
uniprot id: V5S9G5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1029756:W911 RS10430
gene id: 1029756:W911_RS10430
uniprot id: V5SFF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1029756:W911 RS05760
gene id: 1029756:W911_RS05760
uniprot id: V5SC25
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1029756:W911 RS08005
gene id: 1029756:W911_RS08005
uniprot id: V5SEB2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS07685
gene id: 1029756:W911_RS07685
uniprot id: V5SCV1
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1029756:W911 RS14440
gene id: 1029756:W911_RS14440
uniprot id: V5SHG2
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

1029756:W911 RS06355
gene id: 1029756:W911_RS06355
uniprot id: V5SDT7
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS14955
gene id: 1029756:W911_RS14955
uniprot id: V5SHD2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1029756:W911 RS11415
gene id: 1029756:W911_RS11415
uniprot id: V5SG47
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

1029756:W911 RS10150
gene id: 1029756:W911_RS10150
uniprot id: V5SFA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1029756:W911 RS05400
gene id: 1029756:W911_RS05400
uniprot id: V5SAX8
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1029756:W911 RS05735
gene id: 1029756:W911_RS05735
uniprot id: V5SC21
names: Similarity
messages: Belongs to the CFA/CMAS family.

1029756:W911 RS00190
gene id: 1029756:W911_RS00190
uniprot id: V5SB60
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1029756:W911 RS14550
gene id: 1029756:W911_RS14550
uniprot id: V5SFT8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1029756:W911 RS13095
gene id: 1029756:W911_RS13095
uniprot id: V5SFC1
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 copper ion per subunit.
messages: Periplasm

1029756:W911 RS00100
gene id: 1029756:W911_RS00100
uniprot id: V5S951
names: Similarity
messages: Belongs to the PqqA family.

1029756:W911 RS05935
gene id: 1029756:W911_RS05935
uniprot id: V5SB31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1029756:W911 RS09255
gene id: 1029756:W911_RS09255
uniprot id: V5SDL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1029756:W911 RS07945
gene id: 1029756:W911_RS07945
uniprot id: V5SD22
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS16995
gene id: 1029756:W911_RS16995
uniprot id: V5SGX2
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1029756:W911 RS13460
gene id: 1029756:W911_RS13460
uniprot id: V5SFH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1029756:W911 RS15570
gene id: 1029756:W911_RS15570
uniprot id: V5SHZ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1029756:W911 RS15650
gene id: 1029756:W911_RS15650
uniprot id: V5SI10
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1029756:W911 RS13065
gene id: 1029756:W911_RS13065
uniprot id: V5SFB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1029756:W911 RS13575
gene id: 1029756:W911_RS13575
uniprot id: V5SFJ4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1029756:W911 RS10870
gene id: 1029756:W911_RS10870
uniprot id: V5SI85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1029756:W911 RS00860
gene id: 1029756:W911_RS00860
uniprot id: V5SBC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1029756:W911 RS03190
gene id: 1029756:W911_RS03190
uniprot id: V5SA89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1029756:W911 RS04370
gene id: 1029756:W911_RS04370
uniprot id: V5SBH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

1029756:W911 RS08410
gene id: 1029756:W911_RS08410
uniprot id: V5SC45
names: Similarity
messages: Belongs to the acylphosphatase family.

1029756:W911 RS01120
gene id: 1029756:W911_RS01120
uniprot id: V5SBI5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1029756:W911 RS12020
gene id: 1029756:W911_RS12020
uniprot id: V5SEU7
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1029756:W911 RS13620
gene id: 1029756:W911_RS13620
uniprot id: V5SEI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1029756:W911 RS04290
gene id: 1029756:W911_RS04290
uniprot id: V5SJ09
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS03990
gene id: 1029756:W911_RS03990
uniprot id: V5SCS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1029756:W911 RS15260
gene id: 1029756:W911_RS15260
uniprot id: V5SHH9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1029756:W911 RS15695
gene id: 1029756:W911_RS15695
uniprot id: V5SGC7
names: Similarity
messages: Belongs to the peptidase M16 family.

1029756:W911 RS13590
gene id: 1029756:W911_RS13590
uniprot id: V5SGW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1029756:W911 RS09640
gene id: 1029756:W911_RS09640
uniprot id: V5SF15
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1029756:W911 RS04115
gene id: 1029756:W911_RS04115
uniprot id: V5SHB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1029756:W911 RS16860
gene id: 1029756:W911_RS16860
uniprot id: V5SI87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1029756:W911 RS09325
gene id: 1029756:W911_RS09325
uniprot id: V5SDI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1029756:W911 RS13790
gene id: 1029756:W911_RS13790
uniprot id: V5SFQ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1029756:W911 RS11590
gene id: 1029756:W911_RS11590
uniprot id: V5SDK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

1029756:W911 RS04535
gene id: 1029756:W911_RS04535
uniprot id: V5SD26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1029756:W911 RS00905
gene id: 1029756:W911_RS00905
uniprot id: V5S9I5
names: Similarity
messages: Belongs to the thioester dehydratase family. FabA subfamily.

1029756:W911 RS15370
gene id: 1029756:W911_RS15370
uniprot id: V5SF77
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS14425
gene id: 1029756:W911_RS14425
uniprot id: V5SET9
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1029756:W911 RS06410
gene id: 1029756:W911_RS06410
uniprot id: V5SDU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS03955
gene id: 1029756:W911_RS03955
uniprot id: V5SB97
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1029756:W911 RS01135
gene id: 1029756:W911_RS01135
uniprot id: V5SA76
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1029756:W911 RS01895
gene id: 1029756:W911_RS01895
uniprot id: V5SBM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1029756:W911 RS00340
gene id: 1029756:W911_RS00340
uniprot id: V5SIC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

1029756:W911 RS14050
gene id: 1029756:W911_RS14050
uniprot id: V5SH19
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1029756:W911 RS00600
gene id: 1029756:W911_RS00600
uniprot id: V5S8Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

1029756:W911 RS05420
gene id: 1029756:W911_RS05420
uniprot id: V5SD41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1029756:W911 RS03915
gene id: 1029756:W911_RS03915
uniprot id: V5SCQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1029756:W911 RS15390
gene id: 1029756:W911_RS15390
uniprot id: V5SHK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1029756:W911 RS13635
gene id: 1029756:W911_RS13635
uniprot id: V5SH65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1029756:W911 RS09740
gene id: 1029756:W911_RS09740
uniprot id: V5SF28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS11550
gene id: 1029756:W911_RS11550
uniprot id: V5SIB0
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1029756:W911 RS07575
gene id: 1029756:W911_RS07575
uniprot id: V5SCT8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1029756:W911 RS07290
gene id: 1029756:W911_RS07290
uniprot id: V5SCQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1029756:W911 RS14600
gene id: 1029756:W911_RS14600
uniprot id: V5SEW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1029756:W911 RS12280
gene id: 1029756:W911_RS12280
uniprot id: V5SDW6
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.

1029756:W911 RS02150
gene id: 1029756:W911_RS02150
uniprot id: V5SBY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1029756:W911 RS09160
gene id: 1029756:W911_RS09160
uniprot id: V5SDK1
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS12470
gene id: 1029756:W911_RS12470
uniprot id: V5SF24
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

1029756:W911 RS14830
gene id: 1029756:W911_RS14830
uniprot id: V5SG12
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1029756:W911 RS12435
gene id: 1029756:W911_RS12435
uniprot id: V5SGB8
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS06920
gene id: 1029756:W911_RS06920
uniprot id: V5SE12
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1029756:W911 RS06980
gene id: 1029756:W911_RS06980
uniprot id: V5SBC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1029756:W911 RS11085
gene id: 1029756:W911_RS11085
uniprot id: V5SED2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1029756:W911 RS02560
gene id: 1029756:W911_RS02560
uniprot id: V5SAU7
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS06300
gene id: 1029756:W911_RS06300
uniprot id: V5SDS7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1029756:W911 RS00545
gene id: 1029756:W911_RS00545
uniprot id: V5S8Y4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1029756:W911 RS08480
gene id: 1029756:W911_RS08480
uniprot id: V5SD61
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS03925
gene id: 1029756:W911_RS03925
uniprot id: V5SAH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1029756:W911 RS01555
gene id: 1029756:W911_RS01555
uniprot id: V5SBH8
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1029756:W911 RS09765
gene id: 1029756:W911_RS09765
uniprot id: V5SFC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1029756:W911 RS02185
gene id: 1029756:W911_RS02185
uniprot id: V5SBY9
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1029756:W911 RS15935
gene id: 1029756:W911_RS15935
uniprot id: V5SI55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1029756:W911 RS12755
gene id: 1029756:W911_RS12755
uniprot id: V5SE33
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1029756:W911 RS15445
gene id: 1029756:W911_RS15445
uniprot id: V5SF93
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1029756:W911 RS13720
gene id: 1029756:W911_RS13720
uniprot id: V5SGZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS14900
gene id: 1029756:W911_RS14900
uniprot id: V5SF12
names: Similarity
messages: Belongs to the UPF0335 family.

1029756:W911 RS05285
gene id: 1029756:W911_RS05285
uniprot id: V5SD18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS12380
gene id: 1029756:W911_RS12380
uniprot id: V5SEY1
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1029756:W911 RS07435
gene id: 1029756:W911_RS07435
uniprot id: V5SED3
names: Similarity
messages: Belongs to the TlyA family.

1029756:W911 RS13625
gene id: 1029756:W911_RS13625
uniprot id: V5SFL1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1029756:W911 RS16320
gene id: 1029756:W911_RS16320
uniprot id: V5SFK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1029756:W911 RS00400
gene id: 1029756:W911_RS00400
uniprot id: V5SB77
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1029756:W911 RS14895
gene id: 1029756:W911_RS14895
uniprot id: V5SHC4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1029756:W911 RS02140
gene id: 1029756:W911_RS02140
uniprot id: V5SAL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1029756:W911 RS01990
gene id: 1029756:W911_RS01990
uniprot id: V5SAI9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1029756:W911 RS13725
gene id: 1029756:W911_RS13725
uniprot id: V5SEM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1029756:W911 RS12700
gene id: 1029756:W911_RS12700
uniprot id: V5SF60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS00770
gene id: 1029756:W911_RS00770
uniprot id: V5S9Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1029756:W911 RS14540
gene id: 1029756:W911_RS14540
uniprot id: V5SEV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1029756:W911 RS13125
gene id: 1029756:W911_RS13125
uniprot id: V5SFC7
names: Similarity
messages: Belongs to the Gfa family.

1029756:W911 RS14920
gene id: 1029756:W911_RS14920
uniprot id: V5SHC8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1029756:W911 RS14450
gene id: 1029756:W911_RS14450
uniprot id: V5SEU4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1029756:W911 RS01845
gene id: 1029756:W911_RS01845
uniprot id: V5SAG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rho family.
messages: Cell inner membrane
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS05260
gene id: 1029756:W911_RS05260
uniprot id: V5SD15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1029756:W911 RS01995
gene id: 1029756:W911_RS01995
uniprot id: V5SA03
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1029756:W911 RS03770
gene id: 1029756:W911_RS03770
uniprot id: V5SAP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1029756:W911 RS05440
gene id: 1029756:W911_RS05440
uniprot id: V5SDF6
names: Function
names: Similarity
messages: A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
messages: Belongs to the bacterial AtpI family.

1029756:W911 RS04415
gene id: 1029756:W911_RS04415
uniprot id: V5SAQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cytoplasm
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1029756:W911 RS12345
gene id: 1029756:W911_RS12345
uniprot id: V5SDX6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1029756:W911 RS15380
gene id: 1029756:W911_RS15380
uniprot id: V5SG71
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1029756:W911 RS05025
gene id: 1029756:W911_RS05025
uniprot id: V5SD76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1029756:W911 RS00505
gene id: 1029756:W911_RS00505
uniprot id: V5SB83
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1029756:W911 RS12510
gene id: 1029756:W911_RS12510
uniprot id: V5SGM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

1029756:W911 RS08965
gene id: 1029756:W911_RS08965
uniprot id: V5SDD1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1029756:W911 RS00795
gene id: 1029756:W911_RS00795
uniprot id: V5S9Y8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS07750
gene id: 1029756:W911_RS07750
uniprot id: V5SCV9
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

1029756:W911 RS02780
gene id: 1029756:W911_RS02780
uniprot id: V5SC87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1029756:W911 RS16475
gene id: 1029756:W911_RS16475
uniprot id: V5SI19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1029756:W911 RS08640
gene id: 1029756:W911_RS08640
uniprot id: V5SD84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1029756:W911 RS05010
gene id: 1029756:W911_RS05010
uniprot id: V5SAT8
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1029756:W911 RS10880
gene id: 1029756:W911_RS10880
uniprot id: V5SFX6
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1029756:W911 RS05520
gene id: 1029756:W911_RS05520
uniprot id: V5SDH3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1029756:W911 RS13660
gene id: 1029756:W911_RS13660
uniprot id: V5SH88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1029756:W911 RS04965
gene id: 1029756:W911_RS04965
uniprot id: V5SD67
names: Similarity
messages: Belongs to the PqqA family.

1029756:W911 RS08415
gene id: 1029756:W911_RS08415
uniprot id: V5SD93
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1029756:W911 RS05030
gene id: 1029756:W911_RS05030
uniprot id: V5SCX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS16610
gene id: 1029756:W911_RS16610
uniprot id: V5SGT6
names: Similarity
messages: Belongs to the AHA1 family.

1029756:W911 RS12970
gene id: 1029756:W911_RS12970
uniprot id: V5SF79
names: Similarity
messages: Belongs to the PqqA family.

1029756:W911 RS12370
gene id: 1029756:W911_RS12370
uniprot id: V5SDY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1029756:W911 RS15835
gene id: 1029756:W911_RS15835
uniprot id: V5SFE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS15970
gene id: 1029756:W911_RS15970
uniprot id: V5SFH3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS01755
gene id: 1029756:W911_RS01755
uniprot id: V5SBR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1029756:W911 RS05200
gene id: 1029756:W911_RS05200
uniprot id: V5SBS6
names: Similarity
messages: Belongs to the peptidase M17 family.

1029756:W911 RS00345
gene id: 1029756:W911_RS00345
uniprot id: V5SAE4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1029756:W911 RS07145
gene id: 1029756:W911_RS07145
uniprot id: V5SDW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1029756:W911 RS00035
gene id: 1029756:W911_RS00035
uniprot id: V5S8R2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1029756:W911 RS16865
gene id: 1029756:W911_RS16865
uniprot id: V5SFT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1029756:W911 RS01635
gene id: 1029756:W911_RS01635
uniprot id: V5SBP7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1029756:W911 RS06480
gene id: 1029756:W911_RS06480
uniprot id: V5SCC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1029756:W911 RS04255
gene id: 1029756:W911_RS04255
uniprot id: V5SAP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1029756:W911 RS14960
gene id: 1029756:W911_RS14960
uniprot id: V5SF22
names: Similarity
messages: Belongs to the glutamate synthase family.

1029756:W911 RS08735
gene id: 1029756:W911_RS08735
uniprot id: V5SDE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS15580
gene id: 1029756:W911_RS15580
uniprot id: V5SFB9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1029756:W911 RS09870
gene id: 1029756:W911_RS09870
uniprot id: V5SDS4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1029756:W911 RS02320
gene id: 1029756:W911_RS02320
uniprot id: V5S9U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1029756:W911 RS05510
gene id: 1029756:W911_RS05510
uniprot id: V5SBY8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1029756:W911 RS10720
gene id: 1029756:W911_RS10720
uniprot id: V5SE82
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS12615
gene id: 1029756:W911_RS12615
uniprot id: V5SE17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1029756:W911 RS01805
gene id: 1029756:W911_RS01805
uniprot id: V5SBS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1029756:W911 RS03350
gene id: 1029756:W911_RS03350
uniprot id: V5SCC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1029756:W911 RS00625
gene id: 1029756:W911_RS00625
uniprot id: V5SAJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1029756:W911 RS10460
gene id: 1029756:W911_RS10460
uniprot id: V5SFG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1029756:W911 RS00290
gene id: 1029756:W911_RS00290
uniprot id: V5S8U9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1029756:W911 RS03040
gene id: 1029756:W911_RS03040
uniprot id: V5SCD0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1029756:W911 RS05740
gene id: 1029756:W911_RS05740
uniprot id: V5SBX6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1029756:W911 RS12445
gene id: 1029756:W911_RS12445
uniprot id: V5SF20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS00195
gene id: 1029756:W911_RS00195
uniprot id: V5SAC7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1029756:W911 RS15130
gene id: 1029756:W911_RS15130
uniprot id: V5SHS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1029756:W911 RS15410
gene id: 1029756:W911_RS15410
uniprot id: V5SHW5
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS05640
gene id: 1029756:W911_RS05640
uniprot id: V5SD82
names: Function
messages: Multidrug efflux pump.

1029756:W911 RS11140
gene id: 1029756:W911_RS11140
uniprot id: V5SDE3
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1029756:W911 RS15960
gene id: 1029756:W911_RS15960
uniprot id: V5SI58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1029756:W911 RS15685
gene id: 1029756:W911_RS15685
uniprot id: V5SFD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1029756:W911 RS15470
gene id: 1029756:W911_RS15470
uniprot id: V5SHL7
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS13655
gene id: 1029756:W911_RS13655
uniprot id: V5SFK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1029756:W911 RS02785
gene id: 1029756:W911_RS02785
uniprot id: V5SC29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1029756:W911 RS02175
gene id: 1029756:W911_RS02175
uniprot id: V5SA24
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1029756:W911 RS15955
gene id: 1029756:W911_RS15955
uniprot id: V5SGG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1029756:W911 RS13290
gene id: 1029756:W911_RS13290
uniprot id: V5SGZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1029756:W911 RS11465
gene id: 1029756:W911_RS11465
uniprot id: V5SDJ2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1029756:W911 RS00225
gene id: 1029756:W911_RS00225
uniprot id: V5SAD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

1029756:W911 RS05405
gene id: 1029756:W911_RS05405
uniprot id: V5SBW5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1029756:W911 RS11390
gene id: 1029756:W911_RS11390
uniprot id: V5SG44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1029756:W911 RS10120
gene id: 1029756:W911_RS10120
uniprot id: V5SFI0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1029756:W911 RS18115
gene id: 1029756:W911_RS18115
uniprot id: V5SE08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1029756:W911 RS05375
gene id: 1029756:W911_RS05375
uniprot id: V5SAX5
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1029756:W911 RS00150
gene id: 1029756:W911_RS00150
uniprot id: V5S9M5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1029756:W911 RS16340
gene id: 1029756:W911_RS16340
uniprot id: V5SIB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1029756:W911 RS01355
gene id: 1029756:W911_RS01355
uniprot id: V5SBF2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1029756:W911 RS03505
gene id: 1029756:W911_RS03505
uniprot id: V5SB25
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1029756:W911 RS04020
gene id: 1029756:W911_RS04020
uniprot id: V5SCS6
names: Similarity
messages: Belongs to the MotB family.

1029756:W911 RS11320
gene id: 1029756:W911_RS11320
uniprot id: V5SFV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1029756:W911 RS10860
gene id: 1029756:W911_RS10860
uniprot id: V5SDA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1029756:W911 RS06990
gene id: 1029756:W911_RS06990
uniprot id: V5SCG4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1029756:W911 RS02705
gene id: 1029756:W911_RS02705
uniprot id: V5SC19
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1029756:W911 RS15300
gene id: 1029756:W911_RS15300
uniprot id: V5SHI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1029756:W911 RS14140
gene id: 1029756:W911_RS14140
uniprot id: V5SER4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1029756:W911 RS01240
gene id: 1029756:W911_RS01240
uniprot id: V5SA90
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1029756:W911 RS03520
gene id: 1029756:W911_RS03520
uniprot id: V5SAC0
names: Similarity
messages: Belongs to the manganese catalase family.

1029756:W911 RS15290
gene id: 1029756:W911_RS15290
uniprot id: V5SG52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1029756:W911 RS15415
gene id: 1029756:W911_RS15415
uniprot id: V5SHK6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1029756:W911 RS03640
gene id: 1029756:W911_RS03640
uniprot id: V5SCF8
names: Similarity
messages: Belongs to the YggT family.

1029756:W911 RS10305
gene id: 1029756:W911_RS10305
uniprot id: V5SFK4
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1029756:W911 RS15345
gene id: 1029756:W911_RS15345
uniprot id: V5SKA1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

1029756:W911 RS13250
gene id: 1029756:W911_RS13250
uniprot id: V5SEA0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1029756:W911 RS08095
gene id: 1029756:W911_RS08095
uniprot id: V5SEM0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1029756:W911 RS07355
gene id: 1029756:W911_RS07355
uniprot id: V5SE07
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Cytoplasm
messages: Homotetramer.

1029756:W911 RS00865
gene id: 1029756:W911_RS00865
uniprot id: V5SAM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1029756:W911 RS15060
gene id: 1029756:W911_RS15060
uniprot id: V5SF36
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1029756:W911 RS12690
gene id: 1029756:W911_RS12690
uniprot id: V5SGF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1029756:W911 RS00370
gene id: 1029756:W911_RS00370
uniprot id: V5SB74
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1029756:W911 RS04935
gene id: 1029756:W911_RS04935
uniprot id: V5SHG9
names: Similarity
messages: Belongs to the universal stress protein A family.

1029756:W911 RS07760
gene id: 1029756:W911_RS07760
uniprot id: V5SE81
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS08630
gene id: 1029756:W911_RS08630
uniprot id: V5SC79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1029756:W911 RS08555
gene id: 1029756:W911_RS08555
uniprot id: V5SEU3
names: Similarity
messages: Belongs to the YjdM family.

1029756:W911 RS08985
gene id: 1029756:W911_RS08985
uniprot id: V5SCC6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1029756:W911 RS06565
gene id: 1029756:W911_RS06565
uniprot id: V5SCE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1029756:W911 RS15515
gene id: 1029756:W911_RS15515
uniprot id: V5SG96
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1029756:W911 RS13760
gene id: 1029756:W911_RS13760
uniprot id: V5SFP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1029756:W911 RS03315
gene id: 1029756:W911_RS03315
uniprot id: V5SCH8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1029756:W911 RS12340
gene id: 1029756:W911_RS12340
uniprot id: V5SGA5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1029756:W911 RS09070
gene id: 1029756:W911_RS09070
uniprot id: V5SES5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1029756:W911 RS02290
gene id: 1029756:W911_RS02290
uniprot id: V5SAN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1029756:W911 RS01815
gene id: 1029756:W911_RS01815
uniprot id: V5S9K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1029756:W911 RS16095
gene id: 1029756:W911_RS16095
uniprot id: V5SHX4
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS13405
gene id: 1029756:W911_RS13405
uniprot id: V5SFF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

1029756:W911 RS04925
gene id: 1029756:W911_RS04925
uniprot id: V5SBI7
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS15865
gene id: 1029756:W911_RS15865
uniprot id: V5SFF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

1029756:W911 RS08425
gene id: 1029756:W911_RS08425
uniprot id: V5SES4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1029756:W911 RS00945
gene id: 1029756:W911_RS00945
uniprot id: V5S9K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1029756:W911 RS01765
gene id: 1029756:W911_RS01765
uniprot id: V5S9J9
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1029756:W911 RS09925
gene id: 1029756:W911_RS09925
uniprot id: V5SDT4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1029756:W911 RS10895
gene id: 1029756:W911_RS10895
uniprot id: V5SED0
names: Similarity
messages: Belongs to the glutamate synthase family.

1029756:W911 RS11495
gene id: 1029756:W911_RS11495
uniprot id: V5SEL6
names: Similarity
messages: Belongs to the peptidase C14A family.

1029756:W911 RS06185
gene id: 1029756:W911_RS06185
uniprot id: V5SB55
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1029756:W911 RS09705
gene id: 1029756:W911_RS09705
uniprot id: V5SF23
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS10680
gene id: 1029756:W911_RS10680
uniprot id: V5SFL3
names: Function
messages: Acts on leucine, isoleucine and valine.

1029756:W911 RS07030
gene id: 1029756:W911_RS07030
uniprot id: V5SBD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1029756:W911 RS13560
gene id: 1029756:W911_RS13560
uniprot id: V5SH33
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1029756:W911 RS04505
gene id: 1029756:W911_RS04505
uniprot id: V5SD23
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1029756:W911 RS06995
gene id: 1029756:W911_RS06995
uniprot id: V5SE25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1029756:W911 RS09390
gene id: 1029756:W911_RS09390
uniprot id: V5SF70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1029756:W911 RS17205
gene id: 1029756:W911_RS17205
uniprot id: V5SBJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1029756:W911 RS14575
gene id: 1029756:W911_RS14575
uniprot id: V5SFX5
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1029756:W911 RS09065
gene id: 1029756:W911_RS09065
uniprot id: V5SF21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1029756:W911 RS01740
gene id: 1029756:W911_RS01740
uniprot id: V5S9J4
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

1029756:W911 RS00165
gene id: 1029756:W911_RS00165
uniprot id: V5SB57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1029756:W911 RS01745
gene id: 1029756:W911_RS01745
uniprot id: V5SAE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1029756:W911 RS15090
gene id: 1029756:W911_RS15090
uniprot id: V5SF39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1029756:W911 RS09005
gene id: 1029756:W911_RS09005
uniprot id: V5SER3
names: Similarity
messages: Belongs to the YkuD family.

1029756:W911 RS14495
gene id: 1029756:W911_RS14495
uniprot id: V5SFS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1029756:W911 RS04990
gene id: 1029756:W911_RS04990
uniprot id: V5SBN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1029756:W911 RS16725
gene id: 1029756:W911_RS16725
uniprot id: V5SI62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS08370
gene id: 1029756:W911_RS08370
uniprot id: V5SD83
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1029756:W911 RS04260
gene id: 1029756:W911_RS04260
uniprot id: V5SBG4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1029756:W911 RS14520
gene id: 1029756:W911_RS14520
uniprot id: V5SFW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1029756:W911 RS04870
gene id: 1029756:W911_RS04870
uniprot id: V5SD52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

1029756:W911 RS11240
gene id: 1029756:W911_RS11240
uniprot id: V5SEF3
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS02025
gene id: 1029756:W911_RS02025
uniprot id: V5S9P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.
messages: In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed.

1029756:W911 RS06160
gene id: 1029756:W911_RS06160
uniprot id: V5SDR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1029756:W911 RS07400
gene id: 1029756:W911_RS07400
uniprot id: V5SCU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1029756:W911 RS00815
gene id: 1029756:W911_RS00815
uniprot id: V5S934
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1029756:W911 RS07385
gene id: 1029756:W911_RS07385
uniprot id: V5SBP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1029756:W911 RS15305
gene id: 1029756:W911_RS15305
uniprot id: V5SF71
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1029756:W911 RS14680
gene id: 1029756:W911_RS14680
uniprot id: V5SEX9
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1029756:W911 RS13295
gene id: 1029756:W911_RS13295
uniprot id: V5SGR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1029756:W911 RS06745
gene id: 1029756:W911_RS06745
uniprot id: V5SDP2
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1029756:W911 RS13450
gene id: 1029756:W911_RS13450
uniprot id: V5SGU3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from the membrane-anchored tetraheme c-type NapC protein and transfers these to NapA subunit, thus allowing electron flow between membrane and periplasm. Essential for periplasmic nitrate reduction with nitrate as the terminal electron acceptor.
messages: Periplasm

1029756:W911 RS00525
gene id: 1029756:W911_RS00525
uniprot id: V5S9T2
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1029756:W911 RS13150
gene id: 1029756:W911_RS13150
uniprot id: V5SE86
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1029756:W911 RS06795
gene id: 1029756:W911_RS06795
uniprot id: V5SB98
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1029756:W911 RS03950
gene id: 1029756:W911_RS03950
uniprot id: V5SAI1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1029756:W911 RS15600
gene id: 1029756:W911_RS15600
uniprot id: V5SI04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1029756:W911 RS16195
gene id: 1029756:W911_RS16195
uniprot id: V5SGN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1029756:W911 RS02335
gene id: 1029756:W911_RS02335
uniprot id: V5SC17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1029756:W911 RS08075
gene id: 1029756:W911_RS08075
uniprot id: V5SBZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1029756:W911 RS06555
gene id: 1029756:W911_RS06555
uniprot id: V5SDM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1029756:W911 RS01540
gene id: 1029756:W911_RS01540
uniprot id: V5SAC3
names: Similarity
messages: Belongs to the UPF0434 family.

1029756:W911 RS03325
gene id: 1029756:W911_RS03325
uniprot id: V5SAA4
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1029756:W911 RS16915
gene id: 1029756:W911_RS16915
uniprot id: V5SGW1
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS12990
gene id: 1029756:W911_RS12990
uniprot id: V5SGL6
names: Similarity
messages: Belongs to the PhzF family.

1029756:W911 RS04355
gene id: 1029756:W911_RS04355
uniprot id: V5SIN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

1029756:W911 RS12570
gene id: 1029756:W911_RS12570
uniprot id: V5SF09
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1029756:W911 RS14590
gene id: 1029756:W911_RS14590
uniprot id: V5SH77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1029756:W911 RS15840
gene id: 1029756:W911_RS15840
uniprot id: V5SGH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1029756:W911 RS08230
gene id: 1029756:W911_RS08230
uniprot id: V5SD64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1029756:W911 RS16050
gene id: 1029756:W911_RS16050
uniprot id: V5SHW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1029756:W911 RS06345
gene id: 1029756:W911_RS06345
uniprot id: V5SCA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1029756:W911 RS14990
gene id: 1029756:W911_RS14990
uniprot id: V5SF26
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1029756:W911 RS12300
gene id: 1029756:W911_RS12300
uniprot id: V5SGI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS12215
gene id: 1029756:W911_RS12215
uniprot id: V5SEY4
names: Similarity
messages: Belongs to the SufE family.

1029756:W911 RS05495
gene id: 1029756:W911_RS05495
uniprot id: V5SDG7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1029756:W911 RS00900
gene id: 1029756:W911_RS00900
uniprot id: V5SA31
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1029756:W911 RS17095
gene id: 1029756:W911_RS17095
uniprot id: V5SH90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1029756:W911 RS17475
gene id: 1029756:W911_RS17475
uniprot id: V5SFG9
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS07280
gene id: 1029756:W911_RS07280
uniprot id: V5SDZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS15350
gene id: 1029756:W911_RS15350
uniprot id: V5SGA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1029756:W911 RS06730
gene id: 1029756:W911_RS06730
uniprot id: V5SCF7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1029756:W911 RS06875
gene id: 1029756:W911_RS06875
uniprot id: V5SBA7
names: Subcellular Location Annotation
messages: Cytoplasm

1029756:W911 RS05320
gene id: 1029756:W911_RS05320
uniprot id: V5SAX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1029756:W911 RS00550
gene id: 1029756:W911_RS00550
uniprot id: V5S9T7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. BioZ family.
messages: Involved in the formation of the biotin precursor pimeloyl-ACP. Catalyzes the condensation of glutaryl-CoA, an intermediate in lysine degradation, with malonyl-ACP to produce 3-oxopimeloyl-ACP.

1029756:W911 RS12710
gene id: 1029756:W911_RS12710
uniprot id: V5SGQ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

1029756:W911 RS10950
gene id: 1029756:W911_RS10950
uniprot id: V5SEB4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1029756:W911 RS00495
gene id: 1029756:W911_RS00495
uniprot id: V5S9S7
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1029756:W911 RS13955
gene id: 1029756:W911_RS13955
uniprot id: V5SEP1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1029756:W911 RS07775
gene id: 1029756:W911_RS07775
uniprot id: V5SCW2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Binds 2 calcium ions per subunit.
messages: Binds 6 Cu cations per subunit. Each subunit contains 2 copper centers; Cu(A) (binuclear) and Cu(Z) (tetranuclear). Cu(Z) is thought to be the site of nitrous oxide reduction.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1029756:W911 RS14165
gene id: 1029756:W911_RS14165
uniprot id: V5SHE2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1029756:W911 RS13330
gene id: 1029756:W911_RS13330
uniprot id: V5SFG2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1029756:W911 RS00315
gene id: 1029756:W911_RS00315
uniprot id: V5SAD8
names: Similarity
messages: Belongs to the UPF0262 family.

1029756:W911 RS10060
gene id: 1029756:W911_RS10060
uniprot id: V5SFH1
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1029756:W911 RS16305
gene id: 1029756:W911_RS16305
uniprot id: V5SGL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

1029756:W911 RS13195
gene id: 1029756:W911_RS13195
uniprot id: V5SFB5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1029756:W911 RS02445
gene id: 1029756:W911_RS02445
uniprot id: V5SC37
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1029756:W911 RS05275
gene id: 1029756:W911_RS05275
uniprot id: V5SBP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

1029756:W911 RS05545
gene id: 1029756:W911_RS05545
uniprot id: V5SDH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1029756:W911 RS11005
gene id: 1029756:W911_RS11005
uniprot id: V5SFR1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1029756:W911 RS16735
gene id: 1029756:W911_RS16735
uniprot id: V5SGW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1029756:W911 RS02385
gene id: 1029756:W911_RS02385
uniprot id: V5SA51
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS16500
gene id: 1029756:W911_RS16500
uniprot id: V5SIC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1029756:W911 RS01810
gene id: 1029756:W911_RS01810
uniprot id: V5SBL3
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1029756:W911 RS05340
gene id: 1029756:W911_RS05340
uniprot id: V5SAX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

1029756:W911 RS16040
gene id: 1029756:W911_RS16040
uniprot id: V5SGI2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1029756:W911 RS03095
gene id: 1029756:W911_RS03095
uniprot id: V5SCE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS02360
gene id: 1029756:W911_RS02360
uniprot id: V5SA47
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1029756:W911 RS00765
gene id: 1029756:W911_RS00765
uniprot id: V5S923
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1029756:W911 RS03610
gene id: 1029756:W911_RS03610
uniprot id: V5SCL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1029756:W911 RS15075
gene id: 1029756:W911_RS15075
uniprot id: V5SG18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1029756:W911 RS11865
gene id: 1029756:W911_RS11865
uniprot id: V5SEP3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1029756:W911 RS09805
gene id: 1029756:W911_RS09805
uniprot id: V5SF41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1029756:W911 RS12715
gene id: 1029756:W911_RS12715
uniprot id: V5SGG7
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

1029756:W911 RS01605
gene id: 1029756:W911_RS01605
uniprot id: V5SBP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1029756:W911 RS07925
gene id: 1029756:W911_RS07925
uniprot id: V5SCX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1029756:W911 RS09655
gene id: 1029756:W911_RS09655
uniprot id: V5SDS6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1029756:W911 RS10405
gene id: 1029756:W911_RS10405
uniprot id: V5SFF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1029756:W911 RS05125
gene id: 1029756:W911_RS05125
uniprot id: V5SBL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1029756:W911 RS07855
gene id: 1029756:W911_RS07855
uniprot id: V5SE90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

1029756:W911 RS09475
gene id: 1029756:W911_RS09475
uniprot id: V5SDL3
names: Similarity
messages: Belongs to the YkuD family.

1029756:W911 RS03940
gene id: 1029756:W911_RS03940
uniprot id: V5SCR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS06400
gene id: 1029756:W911_RS06400
uniprot id: V5SC73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1029756:W911 RS00745
gene id: 1029756:W911_RS00745
uniprot id: V5S9X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1029756:W911 RS00620
gene id: 1029756:W911_RS00620
uniprot id: V5SB94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1029756:W911 RS11000
gene id: 1029756:W911_RS11000
uniprot id: V5SFZ1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1029756:W911 RS13415
gene id: 1029756:W911_RS13415
uniprot id: V5SGT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemJ family.
messages: Cell membrane
messages: Membrane

1029756:W911 RS10650
gene id: 1029756:W911_RS10650
uniprot id: V5SFU1
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS04235
gene id: 1029756:W911_RS04235
uniprot id: V5SBG1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1029756:W911 RS03015
gene id: 1029756:W911_RS03015
uniprot id: V5SCC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1029756:W911 RS10100
gene id: 1029756:W911_RS10100
uniprot id: V5SF96
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1029756:W911 RS01015
gene id: 1029756:W911_RS01015
uniprot id: V5S9K7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1029756:W911 RS06000
gene id: 1029756:W911_RS06000
uniprot id: V5SC50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

1029756:W911 RS16765
gene id: 1029756:W911_RS16765
uniprot id: V5SGT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1029756:W911 RS11205
gene id: 1029756:W911_RS11205
uniprot id: V5SDF3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1029756:W911 RS09435
gene id: 1029756:W911_RS09435
uniprot id: V5SDP6
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1029756:W911 RS12055
gene id: 1029756:W911_RS12055
uniprot id: V5SES6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1029756:W911 RS10875
gene id: 1029756:W911_RS10875
uniprot id: V5SEA2
names: Similarity
messages: Belongs to the citrate synthase family.

1029756:W911 RS09380
gene id: 1029756:W911_RS09380
uniprot id: V5SDN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cytoplasm
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1029756:W911 RS01195
gene id: 1029756:W911_RS01195
uniprot id: V5S9N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1029756:W911 RS01860
gene id: 1029756:W911_RS01860
uniprot id: V5SBM1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS08510
gene id: 1029756:W911_RS08510
uniprot id: V5SET8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1029756:W911 RS10560
gene id: 1029756:W911_RS10560
uniprot id: V5SE45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1029756:W911 RS10475
gene id: 1029756:W911_RS10475
uniprot id: V5SE28
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1029756:W911 RS16825
gene id: 1029756:W911_RS16825
uniprot id: V5SGU5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1029756:W911 RS09700
gene id: 1029756:W911_RS09700
uniprot id: V5SFB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1029756:W911 RS05425
gene id: 1029756:W911_RS05425
uniprot id: V5SAY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1029756:W911 RS08035
gene id: 1029756:W911_RS08035
uniprot id: V5SEL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1029756:W911 RS00880
gene id: 1029756:W911_RS00880
uniprot id: V5S9H1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1029756:W911 RS02510
gene id: 1029756:W911_RS02510
uniprot id: V5SAU1
names: Function
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.

1029756:W911 RS05225
gene id: 1029756:W911_RS05225
uniprot id: V5SBT0
names: Similarity
messages: Belongs to the GSP E family.

1029756:W911 RS00775
gene id: 1029756:W911_RS00775
uniprot id: V5S9E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1029756:W911 RS15555
gene id: 1029756:W911_RS15555
uniprot id: V5SFB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1029756:W911 RS14795
gene id: 1029756:W911_RS14795
uniprot id: V5SG07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1029756:W911 RS09010
gene id: 1029756:W911_RS09010
uniprot id: V5SCD1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1029756:W911 RS12385
gene id: 1029756:W911_RS12385
uniprot id: V5SGK1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1029756:W911 RS00320
gene id: 1029756:W911_RS00320
uniprot id: V5S8V3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1029756:W911 RS01100
gene id: 1029756:W911_RS01100
uniprot id: V5SBC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1029756:W911 RS01800
gene id: 1029756:W911_RS01800
uniprot id: V5S9X0
names: Similarity
messages: Belongs to the Tim44 family.

1029756:W911 RS02015
gene id: 1029756:W911_RS02015
uniprot id: V5SG60
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1029756:W911 RS02330
gene id: 1029756:W911_RS02330
uniprot id: V5SA44
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1029756:W911 RS16220
gene id: 1029756:W911_RS16220
uniprot id: V5SFJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1029756:W911 RS13565
gene id: 1029756:W911_RS13565
uniprot id: V5SGW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1029756:W911 RS09460
gene id: 1029756:W911_RS09460
uniprot id: V5SCJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.
messages: In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed.

1029756:W911 RS08155
gene id: 1029756:W911_RS08155
uniprot id: V5SD13
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1029756:W911 RS02095
gene id: 1029756:W911_RS02095
uniprot id: V5SBX4
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1029756:W911 RS09490
gene id: 1029756:W911_RS09490
uniprot id: V5SCK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cytoplasm
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1029756:W911 RS13315
gene id: 1029756:W911_RS13315
uniprot id: V5SGZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1029756:W911 RS07405
gene id: 1029756:W911_RS07405
uniprot id: V5SCR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1029756:W911 RS06955
gene id: 1029756:W911_RS06955
uniprot id: V5SBB9
names: Similarity
messages: Belongs to the CobH/CbiC family.

1029756:W911 RS05215
gene id: 1029756:W911_RS05215
uniprot id: V5SD06
names: Subcellular Location Annotation
messages: Membrane

1029756:W911 RS13075
gene id: 1029756:W911_RS13075
uniprot id: V5SGW0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1029756:W911 RS02400
gene id: 1029756:W911_RS02400
uniprot id: V5S9V7
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1029756:W911 RS14845
gene id: 1029756:W911_RS14845
uniprot id: V5SHB5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1029756:W911 RS05015
gene id: 1029756:W911_RS05015
uniprot id: V5SBP1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS00410
gene id: 1029756:W911_RS00410
uniprot id: V5S8W6
names: Similarity
messages: Belongs to the asparagine synthetase family.

1029756:W911 RS10945
gene id: 1029756:W911_RS10945
uniprot id: V5SED9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1029756:W911 RS15900
gene id: 1029756:W911_RS15900
uniprot id: V5SGI8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS07690
gene id: 1029756:W911_RS07690
uniprot id: V5SEH4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS06950
gene id: 1029756:W911_RS06950
uniprot id: V5SDS5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1029756:W911 RS13350
gene id: 1029756:W911_RS13350
uniprot id: V5SHH5
names: Similarity
messages: Belongs to the intimin/invasin family.

1029756:W911 RS11910
gene id: 1029756:W911_RS11910
uniprot id: V5SGC4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS05175
gene id: 1029756:W911_RS05175
uniprot id: V5SBM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1029756:W911 RS06485
gene id: 1029756:W911_RS06485
uniprot id: V5SC88
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1029756:W911 RS01820
gene id: 1029756:W911_RS01820
uniprot id: V5SAG2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS12645
gene id: 1029756:W911_RS12645
uniprot id: V5SF18
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Binds 1 Cu(+) ion.
messages: Homotrimer.
messages: Periplasm

1029756:W911 RS03660
gene id: 1029756:W911_RS03660
uniprot id: V5SCL7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1029756:W911 RS14720
gene id: 1029756:W911_RS14720
uniprot id: V5SH95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1029756:W911 RS13265
gene id: 1029756:W911_RS13265
uniprot id: V5SGY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1029756:W911 RS06720
gene id: 1029756:W911_RS06720
uniprot id: V5SDN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1029756:W911 RS09895
gene id: 1029756:W911_RS09895
uniprot id: V5SDS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1029756:W911 RS10605
gene id: 1029756:W911_RS10605
uniprot id: V5SFK1
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1029756:W911 RS14650
gene id: 1029756:W911_RS14650
uniprot id: V5SH84
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1029756:W911 RS16045
gene id: 1029756:W911_RS16045
uniprot id: V5SI73
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1029756:W911 RS02215
gene id: 1029756:W911_RS02215
uniprot id: V5SBT4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

1029756:W911 RS04725
gene id: 1029756:W911_RS04725
uniprot id: V5SBK7
names: Subcellular Location Annotation
messages: Cytoplasm

1029756:W911 RS11770
gene id: 1029756:W911_RS11770
uniprot id: V5SEQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

1029756:W911 RS05765
gene id: 1029756:W911_RS05765
uniprot id: V5SBY1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1029756:W911 RS10420
gene id: 1029756:W911_RS10420
uniprot id: V5SE18
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1029756:W911 RS03780
gene id: 1029756:W911_RS03780
uniprot id: V5SCI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1029756:W911 RS01070
gene id: 1029756:W911_RS01070
uniprot id: V5SBC0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1029756:W911 RS02395
gene id: 1029756:W911_RS02395
uniprot id: V5SBW6
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

1029756:W911 RS13795
gene id: 1029756:W911_RS13795
uniprot id: V5SFM4
names: Similarity
messages: Belongs to the pirin family.

1029756:W911 RS05155
gene id: 1029756:W911_RS05155
uniprot id: V5SD99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1029756:W911 RS15095
gene id: 1029756:W911_RS15095
uniprot id: V5SG58
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1029756:W911 RS13570
gene id: 1029756:W911_RS13570
uniprot id: V5SEG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1029756:W911 RS12600
gene id: 1029756:W911_RS12600
uniprot id: V5SF14
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

1029756:W911 RS06055
gene id: 1029756:W911_RS06055
uniprot id: V5SB37
names: Subcellular Location Annotation
messages: Membrane