http://togogenome.org/gene/929713:NIASO_RS02670 ^@ http://purl.uniprot.org/uniprot/W0EZ00 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/929713:NIASO_RS17500 ^@ http://purl.uniprot.org/uniprot/W0F5E9 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/929713:NIASO_RS04865 ^@ http://purl.uniprot.org/uniprot/W0F7G6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS04440 ^@ http://purl.uniprot.org/uniprot/W0EV84 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/929713:NIASO_RS01855 ^@ http://purl.uniprot.org/uniprot/W0EU50 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS09790 ^@ http://purl.uniprot.org/uniprot/W0F2C4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS06005 ^@ http://purl.uniprot.org/uniprot/W0F0D1 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/929713:NIASO_RS16930 ^@ http://purl.uniprot.org/uniprot/W0F540 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/929713:NIASO_RS09135 ^@ http://purl.uniprot.org/uniprot/W0F231 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS13120 ^@ http://purl.uniprot.org/uniprot/W0EYZ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS04035 ^@ http://purl.uniprot.org/uniprot/W0EZK6 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/929713:NIASO_RS14595 ^@ http://purl.uniprot.org/uniprot/W0F359 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS17765 ^@ http://purl.uniprot.org/uniprot/W0F150 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/929713:NIASO_RS02325 ^@ http://purl.uniprot.org/uniprot/W0EU76 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/929713:NIASO_RS05620 ^@ http://purl.uniprot.org/uniprot/W0EVM9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS10210 ^@ http://purl.uniprot.org/uniprot/W0F2J8 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/929713:NIASO_RS17400 ^@ http://purl.uniprot.org/uniprot/W0F5D7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS09460 ^@ http://purl.uniprot.org/uniprot/W0F1T6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS10355 ^@ http://purl.uniprot.org/uniprot/W0F167 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/929713:NIASO_RS00435 ^@ http://purl.uniprot.org/uniprot/W0EXZ8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnE family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. http://togogenome.org/gene/929713:NIASO_RS01435 ^@ http://purl.uniprot.org/uniprot/W0EYS6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/929713:NIASO_RS16940 ^@ http://purl.uniprot.org/uniprot/W0F5G7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/929713:NIASO_RS12050 ^@ http://purl.uniprot.org/uniprot/W0EYJ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS07690 ^@ http://purl.uniprot.org/uniprot/W0F022 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase Y family.|||Cell membrane|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/929713:NIASO_RS15270 ^@ http://purl.uniprot.org/uniprot/W0EZZ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/929713:NIASO_RS14875 ^@ http://purl.uniprot.org/uniprot/W0F484 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YejK family.|||nucleoid http://togogenome.org/gene/929713:NIASO_RS16915 ^@ http://purl.uniprot.org/uniprot/W0F0Q4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/929713:NIASO_RS14000 ^@ http://purl.uniprot.org/uniprot/W0F3Q1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/929713:NIASO_RS05070 ^@ http://purl.uniprot.org/uniprot/W0EZ03 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/929713:NIASO_RS02960 ^@ http://purl.uniprot.org/uniprot/W0EY22 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 51 family. http://togogenome.org/gene/929713:NIASO_RS08490 ^@ http://purl.uniprot.org/uniprot/W0EWU3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS15695 ^@ http://purl.uniprot.org/uniprot/W0F3M2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS07020 ^@ http://purl.uniprot.org/uniprot/W0EW92 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS07785 ^@ http://purl.uniprot.org/uniprot/W0EWP8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/929713:NIASO_RS18135 ^@ http://purl.uniprot.org/uniprot/W0F4Q7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/929713:NIASO_RS09030 ^@ http://purl.uniprot.org/uniprot/W0F0L7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/929713:NIASO_RS17595 ^@ http://purl.uniprot.org/uniprot/W0F5U1 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/929713:NIASO_RS19190 ^@ http://purl.uniprot.org/uniprot/W0F1R4 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS04770 ^@ http://purl.uniprot.org/uniprot/W0EVD9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS18680 ^@ http://purl.uniprot.org/uniprot/W0F5W4 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/929713:NIASO_RS16885 ^@ http://purl.uniprot.org/uniprot/W0F0Q0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS02625 ^@ http://purl.uniprot.org/uniprot/W0F758 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/929713:NIASO_RS09340 ^@ http://purl.uniprot.org/uniprot/W0F268 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/929713:NIASO_RS01440 ^@ http://purl.uniprot.org/uniprot/W0ETZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS13835 ^@ http://purl.uniprot.org/uniprot/W0F3M6 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/929713:NIASO_RS15495 ^@ http://purl.uniprot.org/uniprot/W0EZX8 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/929713:NIASO_RS10725 ^@ http://purl.uniprot.org/uniprot/W0F2B3 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/929713:NIASO_RS01030 ^@ http://purl.uniprot.org/uniprot/W0EYB0 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/929713:NIASO_RS15830 ^@ http://purl.uniprot.org/uniprot/W0F078 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/929713:NIASO_RS03740 ^@ http://purl.uniprot.org/uniprot/W0EUY3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS00860 ^@ http://purl.uniprot.org/uniprot/W0EX50 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/929713:NIASO_RS07425 ^@ http://purl.uniprot.org/uniprot/W0EWF5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 28 family. http://togogenome.org/gene/929713:NIASO_RS18040 ^@ http://purl.uniprot.org/uniprot/W0F141 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/929713:NIASO_RS15160 ^@ http://purl.uniprot.org/uniprot/W0F4Q1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS11725 ^@ http://purl.uniprot.org/uniprot/W0F3A3 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/929713:NIASO_RS04250 ^@ http://purl.uniprot.org/uniprot/W0EYP4 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase S45 family.|||Binds 1 Ca(2+) ion per dimer. http://togogenome.org/gene/929713:NIASO_RS17545 ^@ http://purl.uniprot.org/uniprot/W0F4G7 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS02910 ^@ http://purl.uniprot.org/uniprot/W0EZ43 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/929713:NIASO_RS00060 ^@ http://purl.uniprot.org/uniprot/W0EWS6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/929713:NIASO_RS17185 ^@ http://purl.uniprot.org/uniprot/W0F486 ^@ Function|||Similarity ^@ Belongs to the LpxB family.|||Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/929713:NIASO_RS17860 ^@ http://purl.uniprot.org/uniprot/W0F164 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnD subfamily.|||Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/929713:NIASO_RS00500 ^@ http://purl.uniprot.org/uniprot/W0ETE2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS16580 ^@ http://purl.uniprot.org/uniprot/W0F3Y1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS15595 ^@ http://purl.uniprot.org/uniprot/W0F4X5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS02600 ^@ http://purl.uniprot.org/uniprot/W0EXX0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/929713:NIASO_RS16125 ^@ http://purl.uniprot.org/uniprot/W0F080 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the peroxidase family. Peroxidase/catalase subfamily.|||Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.|||Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS07860 ^@ http://purl.uniprot.org/uniprot/W0EWR3 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/929713:NIASO_RS02875 ^@ http://purl.uniprot.org/uniprot/W0EZ37 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/929713:NIASO_RS11930 ^@ http://purl.uniprot.org/uniprot/W0F1Z6 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/929713:NIASO_RS10945 ^@ http://purl.uniprot.org/uniprot/W0F1I4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS06265 ^@ http://purl.uniprot.org/uniprot/W0F0T0 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/929713:NIASO_RS06515 ^@ http://purl.uniprot.org/uniprot/W0F0K9 ^@ Similarity ^@ Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily. http://togogenome.org/gene/929713:NIASO_RS10670 ^@ http://purl.uniprot.org/uniprot/W0F2A4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/929713:NIASO_RS07790 ^@ http://purl.uniprot.org/uniprot/W0F040 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/929713:NIASO_RS03425 ^@ http://purl.uniprot.org/uniprot/W0EUT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM175 family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS14335 ^@ http://purl.uniprot.org/uniprot/W0F315 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/929713:NIASO_RS12760 ^@ http://purl.uniprot.org/uniprot/W0F3Y0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS11395 ^@ http://purl.uniprot.org/uniprot/W0F2M6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/929713:NIASO_RS03935 ^@ http://purl.uniprot.org/uniprot/W0EV15 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS15525 ^@ http://purl.uniprot.org/uniprot/W0F4W3 ^@ Similarity ^@ Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family. http://togogenome.org/gene/929713:NIASO_RS06810 ^@ http://purl.uniprot.org/uniprot/W0EW49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS00795 ^@ http://purl.uniprot.org/uniprot/W0ETP1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.|||Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS05180 ^@ http://purl.uniprot.org/uniprot/W0EVI7 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/929713:NIASO_RS10510 ^@ http://purl.uniprot.org/uniprot/W0F2N5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/929713:NIASO_RS06640 ^@ http://purl.uniprot.org/uniprot/W0EW14 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/929713:NIASO_RS12395 ^@ http://purl.uniprot.org/uniprot/W0EYJ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS01035 ^@ http://purl.uniprot.org/uniprot/W0ETQ6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/929713:NIASO_RS04265 ^@ http://purl.uniprot.org/uniprot/W0EV59 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/929713:NIASO_RS17070 ^@ http://purl.uniprot.org/uniprot/W0F5J0 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/929713:NIASO_RS13345 ^@ http://purl.uniprot.org/uniprot/W0F3U9 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/929713:NIASO_RS01360 ^@ http://purl.uniprot.org/uniprot/W0ETU2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/929713:NIASO_RS17350 ^@ http://purl.uniprot.org/uniprot/W0F5A3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 28 family. http://togogenome.org/gene/929713:NIASO_RS14200 ^@ http://purl.uniprot.org/uniprot/W0F3S1 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS14265 ^@ http://purl.uniprot.org/uniprot/W0EZK0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS16455 ^@ http://purl.uniprot.org/uniprot/W0F4X3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS17665 ^@ http://purl.uniprot.org/uniprot/W0F4I6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS04270 ^@ http://purl.uniprot.org/uniprot/W0F010 ^@ Function|||Similarity ^@ Belongs to the TrhO family.|||Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs. http://togogenome.org/gene/929713:NIASO_RS04375 ^@ http://purl.uniprot.org/uniprot/W0EYR2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/929713:NIASO_RS12325 ^@ http://purl.uniprot.org/uniprot/W0F2Z4 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/929713:NIASO_RS18375 ^@ http://purl.uniprot.org/uniprot/W0F1D1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS17495 ^@ http://purl.uniprot.org/uniprot/W0F4F7 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/929713:NIASO_RS17930 ^@ http://purl.uniprot.org/uniprot/W0F4M7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/929713:NIASO_RS06220 ^@ http://purl.uniprot.org/uniprot/W0F0G3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS05900 ^@ http://purl.uniprot.org/uniprot/W0EVR6 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/929713:NIASO_RS19080 ^@ http://purl.uniprot.org/uniprot/W0F6F4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0394 family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS05685 ^@ http://purl.uniprot.org/uniprot/W0EVN7 ^@ Caution|||Function|||Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS07285 ^@ http://purl.uniprot.org/uniprot/W0F176 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/929713:NIASO_RS11575 ^@ http://purl.uniprot.org/uniprot/W0EYC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/929713:NIASO_RS17925 ^@ http://purl.uniprot.org/uniprot/W0F172 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS02765 ^@ http://purl.uniprot.org/uniprot/W0EZ14 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS13215 ^@ http://purl.uniprot.org/uniprot/W0F3T6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS09945 ^@ http://purl.uniprot.org/uniprot/W0EXG5 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/929713:NIASO_RS11400 ^@ http://purl.uniprot.org/uniprot/W0EY55 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/929713:NIASO_RS15015 ^@ http://purl.uniprot.org/uniprot/W0EZV7 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/929713:NIASO_RS00270 ^@ http://purl.uniprot.org/uniprot/W0EXX6 ^@ Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/929713:NIASO_RS01525 ^@ http://purl.uniprot.org/uniprot/W0EU04 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS05760 ^@ http://purl.uniprot.org/uniprot/W0EVN6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/929713:NIASO_RS20480 ^@ http://purl.uniprot.org/uniprot/W0EYR4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/929713:NIASO_RS13565 ^@ http://purl.uniprot.org/uniprot/W0EZ60 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS04825 ^@ http://purl.uniprot.org/uniprot/W0EVE8 ^@ Function|||Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.|||Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate. http://togogenome.org/gene/929713:NIASO_RS11175 ^@ http://purl.uniprot.org/uniprot/W0EY81 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/929713:NIASO_RS09070 ^@ http://purl.uniprot.org/uniprot/W0EX25 ^@ Similarity ^@ Belongs to the 5'(3')-deoxyribonucleotidase family. http://togogenome.org/gene/929713:NIASO_RS09315 ^@ http://purl.uniprot.org/uniprot/W0F0R7 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit A family. http://togogenome.org/gene/929713:NIASO_RS11630 ^@ http://purl.uniprot.org/uniprot/W0F1U3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/929713:NIASO_RS15450 ^@ http://purl.uniprot.org/uniprot/W0F4U8 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/929713:NIASO_RS17610 ^@ http://purl.uniprot.org/uniprot/W0F4H6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/929713:NIASO_RS08760 ^@ http://purl.uniprot.org/uniprot/W0F1X2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS06840 ^@ http://purl.uniprot.org/uniprot/W0F305 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS08780 ^@ http://purl.uniprot.org/uniprot/W0EWY1 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/929713:NIASO_RS08045 ^@ http://purl.uniprot.org/uniprot/W0F079 ^@ Function|||Similarity ^@ Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/929713:NIASO_RS18920 ^@ http://purl.uniprot.org/uniprot/W0F1G7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS06025 ^@ http://purl.uniprot.org/uniprot/W0EZC4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/929713:NIASO_RS04575 ^@ http://purl.uniprot.org/uniprot/W0EYU3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/929713:NIASO_RS05845 ^@ http://purl.uniprot.org/uniprot/W0F0M5 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/929713:NIASO_RS18140 ^@ http://purl.uniprot.org/uniprot/W0F5N8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/929713:NIASO_RS03250 ^@ http://purl.uniprot.org/uniprot/W0EZ98 ^@ Similarity ^@ Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily. http://togogenome.org/gene/929713:NIASO_RS01005 ^@ http://purl.uniprot.org/uniprot/W0EXA1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS12230 ^@ http://purl.uniprot.org/uniprot/W0F3H6 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family. http://togogenome.org/gene/929713:NIASO_RS08620 ^@ http://purl.uniprot.org/uniprot/W0EWV9 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/929713:NIASO_RS04150 ^@ http://purl.uniprot.org/uniprot/W0EYK4 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. http://togogenome.org/gene/929713:NIASO_RS04365 ^@ http://purl.uniprot.org/uniprot/W0F024 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/929713:NIASO_RS01975 ^@ http://purl.uniprot.org/uniprot/W0EU70 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/929713:NIASO_RS07810 ^@ http://purl.uniprot.org/uniprot/W0EWQ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/929713:NIASO_RS04085 ^@ http://purl.uniprot.org/uniprot/W0EZW3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the selenophosphate synthase 1 family. Class I subfamily.|||Binds 1 Mg(2+) ion per monomer.|||Homodimer.|||Synthesizes selenophosphate from selenide and ATP. http://togogenome.org/gene/929713:NIASO_RS02040 ^@ http://purl.uniprot.org/uniprot/W0EXP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS09350 ^@ http://purl.uniprot.org/uniprot/W0F0S2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/929713:NIASO_RS08775 ^@ http://purl.uniprot.org/uniprot/W0F1I8 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/929713:NIASO_RS10450 ^@ http://purl.uniprot.org/uniprot/W0EXV6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/929713:NIASO_RS07825 ^@ http://purl.uniprot.org/uniprot/W0EWL8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/929713:NIASO_RS18760 ^@ http://purl.uniprot.org/uniprot/W0F1E5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS13540 ^@ http://purl.uniprot.org/uniprot/W0F3I0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS02660 ^@ http://purl.uniprot.org/uniprot/W0EUF5 ^@ Similarity ^@ Belongs to the NusB family. http://togogenome.org/gene/929713:NIASO_RS19130 ^@ http://purl.uniprot.org/uniprot/W0F1K1 ^@ Cofactor ^@ Binds 1 copper ion per subunit, denoted as copper B.|||Binds 2 heme groups per subunit, denoted as high- and low-spin. http://togogenome.org/gene/929713:NIASO_RS13995 ^@ http://purl.uniprot.org/uniprot/W0F2U6 ^@ Similarity ^@ Belongs to the ComB family. http://togogenome.org/gene/929713:NIASO_RS07335 ^@ http://purl.uniprot.org/uniprot/W0EWD8 ^@ Similarity ^@ Belongs to the arginine deiminase family. http://togogenome.org/gene/929713:NIASO_RS10005 ^@ http://purl.uniprot.org/uniprot/W0F2G0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/929713:NIASO_RS07865 ^@ http://purl.uniprot.org/uniprot/W0F055 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/929713:NIASO_RS17085 ^@ http://purl.uniprot.org/uniprot/W0F9D8 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/929713:NIASO_RS15105 ^@ http://purl.uniprot.org/uniprot/W0EZR4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/929713:NIASO_RS18290 ^@ http://purl.uniprot.org/uniprot/W0F628 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/929713:NIASO_RS10465 ^@ http://purl.uniprot.org/uniprot/W0F185 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HAK/KUP transporter (TC 2.A.72) family.|||Cell membrane|||Membrane|||Transport of potassium into the cell. http://togogenome.org/gene/929713:NIASO_RS16370 ^@ http://purl.uniprot.org/uniprot/W0F0B9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/929713:NIASO_RS18000 ^@ http://purl.uniprot.org/uniprot/W0F137 ^@ Function|||Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.|||Homotetramer. http://togogenome.org/gene/929713:NIASO_RS04220 ^@ http://purl.uniprot.org/uniprot/W0EYN9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS00870 ^@ http://purl.uniprot.org/uniprot/W0EY62 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/929713:NIASO_RS01925 ^@ http://purl.uniprot.org/uniprot/W0EYN1 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/929713:NIASO_RS17260 ^@ http://purl.uniprot.org/uniprot/W0F5N0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxC family.|||Belongs to the thioester dehydratase family. FabZ subfamily.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/929713:NIASO_RS07160 ^@ http://purl.uniprot.org/uniprot/W0EWC0 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/929713:NIASO_RS10655 ^@ http://purl.uniprot.org/uniprot/W0F2R5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/929713:NIASO_RS06780 ^@ http://purl.uniprot.org/uniprot/W0F0P7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the arabinose isomerase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of L-arabinose to L-ribulose. http://togogenome.org/gene/929713:NIASO_RS13060 ^@ http://purl.uniprot.org/uniprot/W0F2E1 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/929713:NIASO_RS11120 ^@ http://purl.uniprot.org/uniprot/W0F1L9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer.|||In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.|||In the N-terminal section; belongs to the MIP18 family. http://togogenome.org/gene/929713:NIASO_RS02305 ^@ http://purl.uniprot.org/uniprot/W0EZ54 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/929713:NIASO_RS18165 ^@ http://purl.uniprot.org/uniprot/W0F5P3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS06620 ^@ http://purl.uniprot.org/uniprot/W0F0X0 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Requires K(+) for maximal activity.|||Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. http://togogenome.org/gene/929713:NIASO_RS04275 ^@ http://purl.uniprot.org/uniprot/W0EV83 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/929713:NIASO_RS07965 ^@ http://purl.uniprot.org/uniprot/W0F195 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/929713:NIASO_RS08890 ^@ http://purl.uniprot.org/uniprot/W0EX48 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/929713:NIASO_RS00105 ^@ http://purl.uniprot.org/uniprot/W0EY53 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS14840 ^@ http://purl.uniprot.org/uniprot/W0F493 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS06470 ^@ http://purl.uniprot.org/uniprot/W0F0K3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS17875 ^@ http://purl.uniprot.org/uniprot/W0F4L6 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS16385 ^@ http://purl.uniprot.org/uniprot/W0F3V5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS18415 ^@ http://purl.uniprot.org/uniprot/W0F189 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/929713:NIASO_RS06735 ^@ http://purl.uniprot.org/uniprot/W0F0Y7 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS09995 ^@ http://purl.uniprot.org/uniprot/W0F213 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/929713:NIASO_RS13660 ^@ http://purl.uniprot.org/uniprot/W0F3J7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/929713:NIASO_RS02580 ^@ http://purl.uniprot.org/uniprot/W0EYY5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 16 family. http://togogenome.org/gene/929713:NIASO_RS11845 ^@ http://purl.uniprot.org/uniprot/W0EYB3 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/929713:NIASO_RS10550 ^@ http://purl.uniprot.org/uniprot/W0EXW8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/929713:NIASO_RS06900 ^@ http://purl.uniprot.org/uniprot/W0F113 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS12080 ^@ http://purl.uniprot.org/uniprot/W0EYJ5 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/929713:NIASO_RS04355 ^@ http://purl.uniprot.org/uniprot/W0EZS5 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/929713:NIASO_RS07170 ^@ http://purl.uniprot.org/uniprot/W0F0V4 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/929713:NIASO_RS01455 ^@ http://purl.uniprot.org/uniprot/W0ETV4 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS17395 ^@ http://purl.uniprot.org/uniprot/W0F4E3 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/929713:NIASO_RS06845 ^@ http://purl.uniprot.org/uniprot/W0F0Q7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS03820 ^@ http://purl.uniprot.org/uniprot/W0EUZ4 ^@ Similarity ^@ Belongs to the N-acylglucosamine 2-epimerase family. http://togogenome.org/gene/929713:NIASO_RS09840 ^@ http://purl.uniprot.org/uniprot/W0F1Y7 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS18900 ^@ http://purl.uniprot.org/uniprot/W0F6C6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/929713:NIASO_RS11665 ^@ http://purl.uniprot.org/uniprot/W0EY88 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/929713:NIASO_RS04155 ^@ http://purl.uniprot.org/uniprot/W0EZM3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS05295 ^@ http://purl.uniprot.org/uniprot/W0F698 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS19325 ^@ http://purl.uniprot.org/uniprot/W0F6I2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/929713:NIASO_RS13950 ^@ http://purl.uniprot.org/uniprot/W0F433 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 28 family. http://togogenome.org/gene/929713:NIASO_RS13075 ^@ http://purl.uniprot.org/uniprot/W0F3S3 ^@ Similarity ^@ Belongs to the DinB family. http://togogenome.org/gene/929713:NIASO_RS02790 ^@ http://purl.uniprot.org/uniprot/W0EZ20 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/929713:NIASO_RS05235 ^@ http://purl.uniprot.org/uniprot/W0F026 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/929713:NIASO_RS17145 ^@ http://purl.uniprot.org/uniprot/W0F0T7 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/929713:NIASO_RS17850 ^@ http://purl.uniprot.org/uniprot/W0F5X6 ^@ Similarity ^@ Belongs to the PTPS family. QueD subfamily. http://togogenome.org/gene/929713:NIASO_RS19030 ^@ http://purl.uniprot.org/uniprot/W0F643 ^@ Similarity ^@ Belongs to the MQO family. http://togogenome.org/gene/929713:NIASO_RS20485 ^@ http://purl.uniprot.org/uniprot/W0EUE4 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/929713:NIASO_RS08355 ^@ http://purl.uniprot.org/uniprot/W0EWT3 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/929713:NIASO_RS11110 ^@ http://purl.uniprot.org/uniprot/W0F308 ^@ Similarity ^@ Belongs to the barstar family. http://togogenome.org/gene/929713:NIASO_RS17600 ^@ http://purl.uniprot.org/uniprot/W0F879 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/929713:NIASO_RS03670 ^@ http://purl.uniprot.org/uniprot/W0EUX2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/929713:NIASO_RS12900 ^@ http://purl.uniprot.org/uniprot/W0F451 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS08200 ^@ http://purl.uniprot.org/uniprot/W0F1C6 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/929713:NIASO_RS01270 ^@ http://purl.uniprot.org/uniprot/W0EYE8 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/929713:NIASO_RS18595 ^@ http://purl.uniprot.org/uniprot/W0F4X9 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS15315 ^@ http://purl.uniprot.org/uniprot/W0F4E0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/929713:NIASO_RS03105 ^@ http://purl.uniprot.org/uniprot/W0EZG5 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/929713:NIASO_RS12415 ^@ http://purl.uniprot.org/uniprot/W0F8G4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/929713:NIASO_RS10275 ^@ http://purl.uniprot.org/uniprot/W0F255 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/929713:NIASO_RS09925 ^@ http://purl.uniprot.org/uniprot/W0F2E6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/929713:NIASO_RS05675 ^@ http://purl.uniprot.org/uniprot/W0EVM1 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/929713:NIASO_RS07840 ^@ http://purl.uniprot.org/uniprot/W0F050 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/929713:NIASO_RS10410 ^@ http://purl.uniprot.org/uniprot/W0F179 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/929713:NIASO_RS03535 ^@ http://purl.uniprot.org/uniprot/W0EZM5 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/929713:NIASO_RS11850 ^@ http://purl.uniprot.org/uniprot/W0F3C5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS05945 ^@ http://purl.uniprot.org/uniprot/W0EZA9 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/929713:NIASO_RS01375 ^@ http://purl.uniprot.org/uniprot/W0EYR8 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/929713:NIASO_RS11485 ^@ http://purl.uniprot.org/uniprot/W0EYB5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS18835 ^@ http://purl.uniprot.org/uniprot/W0F1F6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/929713:NIASO_RS13025 ^@ http://purl.uniprot.org/uniprot/W0F3R4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/929713:NIASO_RS06370 ^@ http://purl.uniprot.org/uniprot/W0F0U4 ^@ Similarity ^@ Belongs to the homogentisate dioxygenase family. http://togogenome.org/gene/929713:NIASO_RS09745 ^@ http://purl.uniprot.org/uniprot/W0F1X3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/929713:NIASO_RS00640 ^@ http://purl.uniprot.org/uniprot/W0EY24 ^@ Function ^@ Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate. http://togogenome.org/gene/929713:NIASO_RS02855 ^@ http://purl.uniprot.org/uniprot/W0EZD3 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/929713:NIASO_RS09820 ^@ http://purl.uniprot.org/uniprot/W0EXD8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS01265 ^@ http://purl.uniprot.org/uniprot/W0EXD6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/929713:NIASO_RS14565 ^@ http://purl.uniprot.org/uniprot/W0EZP5 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/929713:NIASO_RS09580 ^@ http://purl.uniprot.org/uniprot/W0F1V0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/929713:NIASO_RS11055 ^@ http://purl.uniprot.org/uniprot/W0F2I1 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/929713:NIASO_RS15250 ^@ http://purl.uniprot.org/uniprot/W0F3E9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS07855 ^@ http://purl.uniprot.org/uniprot/W0F1I9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/929713:NIASO_RS02555 ^@ http://purl.uniprot.org/uniprot/W0EZ91 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M4 family.|||Extracellular zinc metalloprotease.|||Secreted http://togogenome.org/gene/929713:NIASO_RS09555 ^@ http://purl.uniprot.org/uniprot/W0F1U6 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS02665 ^@ http://purl.uniprot.org/uniprot/W0EXX9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/929713:NIASO_RS03405 ^@ http://purl.uniprot.org/uniprot/W0EY87 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS06850 ^@ http://purl.uniprot.org/uniprot/W0F7V2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS17830 ^@ http://purl.uniprot.org/uniprot/W0F160 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS17275 ^@ http://purl.uniprot.org/uniprot/W0F587 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/929713:NIASO_RS15330 ^@ http://purl.uniprot.org/uniprot/W0F4T0 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/929713:NIASO_RS05890 ^@ http://purl.uniprot.org/uniprot/W0F0N0 ^@ Similarity ^@ Belongs to the UPF0162 family. http://togogenome.org/gene/929713:NIASO_RS01245 ^@ http://purl.uniprot.org/uniprot/W0EYQ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS18945 ^@ http://purl.uniprot.org/uniprot/W0F1H2 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS10065 ^@ http://purl.uniprot.org/uniprot/W0EXI8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase. http://togogenome.org/gene/929713:NIASO_RS15175 ^@ http://purl.uniprot.org/uniprot/W0F4B7 ^@ Similarity ^@ Belongs to the DSD1 family. http://togogenome.org/gene/929713:NIASO_RS07705 ^@ http://purl.uniprot.org/uniprot/W0F1H0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/929713:NIASO_RS00760 ^@ http://purl.uniprot.org/uniprot/W0ETN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS14545 ^@ http://purl.uniprot.org/uniprot/W0F349 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS05800 ^@ http://purl.uniprot.org/uniprot/W0EZ90 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the PRA-PH family.|||In the N-terminal section; belongs to the PRA-CH family. http://togogenome.org/gene/929713:NIASO_RS11440 ^@ http://purl.uniprot.org/uniprot/W0F8L6 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS17995 ^@ http://purl.uniprot.org/uniprot/W0F5M1 ^@ Similarity ^@ Belongs to the DinB family. http://togogenome.org/gene/929713:NIASO_RS00685 ^@ http://purl.uniprot.org/uniprot/W0F5E3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS10650 ^@ http://purl.uniprot.org/uniprot/W0EXT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/929713:NIASO_RS03705 ^@ http://purl.uniprot.org/uniprot/W0EZP8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/929713:NIASO_RS03930 ^@ http://purl.uniprot.org/uniprot/W0EZT6 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/929713:NIASO_RS18905 ^@ http://purl.uniprot.org/uniprot/W0F1L7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/929713:NIASO_RS16395 ^@ http://purl.uniprot.org/uniprot/W0F0C5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS03835 ^@ http://purl.uniprot.org/uniprot/W0EUW9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS01460 ^@ http://purl.uniprot.org/uniprot/W0EYT1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/929713:NIASO_RS03630 ^@ http://purl.uniprot.org/uniprot/W0F2F8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS13515 ^@ http://purl.uniprot.org/uniprot/W0F3H5 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/929713:NIASO_RS10685 ^@ http://purl.uniprot.org/uniprot/W0EXZ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/929713:NIASO_RS12100 ^@ http://purl.uniprot.org/uniprot/W0F2W5 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/929713:NIASO_RS01500 ^@ http://purl.uniprot.org/uniprot/W0EXG7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/929713:NIASO_RS07475 ^@ http://purl.uniprot.org/uniprot/W0F100 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS13365 ^@ http://purl.uniprot.org/uniprot/W0F3F2 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/929713:NIASO_RS01400 ^@ http://purl.uniprot.org/uniprot/W0ETU7 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/929713:NIASO_RS04735 ^@ http://purl.uniprot.org/uniprot/W0EVD6 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/929713:NIASO_RS10665 ^@ http://purl.uniprot.org/uniprot/W0F1C1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS12520 ^@ http://purl.uniprot.org/uniprot/W0EYQ2 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/929713:NIASO_RS04715 ^@ http://purl.uniprot.org/uniprot/W0EYV4 ^@ Function|||Similarity ^@ Belongs to the UPF0677 family.|||Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. http://togogenome.org/gene/929713:NIASO_RS19035 ^@ http://purl.uniprot.org/uniprot/W0F1I6 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/929713:NIASO_RS18800 ^@ http://purl.uniprot.org/uniprot/W0F518 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/929713:NIASO_RS09270 ^@ http://purl.uniprot.org/uniprot/W0EX60 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/929713:NIASO_RS14900 ^@ http://purl.uniprot.org/uniprot/W0F488 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS04030 ^@ http://purl.uniprot.org/uniprot/W0EYI9 ^@ Function ^@ Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/929713:NIASO_RS11265 ^@ http://purl.uniprot.org/uniprot/W0F332 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS07510 ^@ http://purl.uniprot.org/uniprot/W0EWH2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/929713:NIASO_RS17540 ^@ http://purl.uniprot.org/uniprot/W0F125 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS06595 ^@ http://purl.uniprot.org/uniprot/W0EZI3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS09675 ^@ http://purl.uniprot.org/uniprot/W0F0V7 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/929713:NIASO_RS17000 ^@ http://purl.uniprot.org/uniprot/W0F0S0 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/929713:NIASO_RS12635 ^@ http://purl.uniprot.org/uniprot/W0F290 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS16530 ^@ http://purl.uniprot.org/uniprot/W0F0J2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS00330 ^@ http://purl.uniprot.org/uniprot/W0EXY4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/929713:NIASO_RS03715 ^@ http://purl.uniprot.org/uniprot/W0EUX8 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/929713:NIASO_RS05910 ^@ http://purl.uniprot.org/uniprot/W0EZA6 ^@ Similarity ^@ Belongs to the GroES chaperonin family. http://togogenome.org/gene/929713:NIASO_RS14185 ^@ http://purl.uniprot.org/uniprot/W0EZF6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS01690 ^@ http://purl.uniprot.org/uniprot/W0EU25 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/929713:NIASO_RS14480 ^@ http://purl.uniprot.org/uniprot/W0F339 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/929713:NIASO_RS12545 ^@ http://purl.uniprot.org/uniprot/W0F3M4 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/929713:NIASO_RS10140 ^@ http://purl.uniprot.org/uniprot/W0F135 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/929713:NIASO_RS03770 ^@ http://purl.uniprot.org/uniprot/W0EZG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS02595 ^@ http://purl.uniprot.org/uniprot/W0EUE8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 51 family. http://togogenome.org/gene/929713:NIASO_RS10020 ^@ http://purl.uniprot.org/uniprot/W0F115 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/929713:NIASO_RS13530 ^@ http://purl.uniprot.org/uniprot/W0EZ56 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/929713:NIASO_RS02650 ^@ http://purl.uniprot.org/uniprot/W0EUC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS08080 ^@ http://purl.uniprot.org/uniprot/W0F084 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS16400 ^@ http://purl.uniprot.org/uniprot/W0F590 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/929713:NIASO_RS06235 ^@ http://purl.uniprot.org/uniprot/W0F0S4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/929713:NIASO_RS01000 ^@ http://purl.uniprot.org/uniprot/W0F1X9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS06540 ^@ http://purl.uniprot.org/uniprot/W0EZI0 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/929713:NIASO_RS08965 ^@ http://purl.uniprot.org/uniprot/W0F1L1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS11130 ^@ http://purl.uniprot.org/uniprot/W0EY28 ^@ Similarity ^@ Belongs to the DapB family. http://togogenome.org/gene/929713:NIASO_RS17270 ^@ http://purl.uniprot.org/uniprot/W0F4A2 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/929713:NIASO_RS07040 ^@ http://purl.uniprot.org/uniprot/W0F133 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/929713:NIASO_RS03975 ^@ http://purl.uniprot.org/uniprot/W0EZJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS12630 ^@ http://purl.uniprot.org/uniprot/W0EYR5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS05715 ^@ http://purl.uniprot.org/uniprot/W0EVP1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS14010 ^@ http://purl.uniprot.org/uniprot/W0F443 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS16835 ^@ http://purl.uniprot.org/uniprot/W0F426 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/929713:NIASO_RS06890 ^@ http://purl.uniprot.org/uniprot/W0F7J6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS10935 ^@ http://purl.uniprot.org/uniprot/W0EY49 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS19460 ^@ http://purl.uniprot.org/uniprot/W0F1Q2 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/929713:NIASO_RS05965 ^@ http://purl.uniprot.org/uniprot/W0EVS4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/929713:NIASO_RS13085 ^@ http://purl.uniprot.org/uniprot/W0F2E5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/929713:NIASO_RS02080 ^@ http://purl.uniprot.org/uniprot/W0EZ27 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UreE family.|||Cytoplasm|||Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. http://togogenome.org/gene/929713:NIASO_RS03545 ^@ http://purl.uniprot.org/uniprot/W0EYA6 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/929713:NIASO_RS11140 ^@ http://purl.uniprot.org/uniprot/W0F313 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/929713:NIASO_RS07630 ^@ http://purl.uniprot.org/uniprot/W0EWJ7 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/929713:NIASO_RS02330 ^@ http://purl.uniprot.org/uniprot/W0EZ58 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/929713:NIASO_RS06775 ^@ http://purl.uniprot.org/uniprot/W0EZK9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS19345 ^@ http://purl.uniprot.org/uniprot/W0F685 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/929713:NIASO_RS16380 ^@ http://purl.uniprot.org/uniprot/W0F0G6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/929713:NIASO_RS11920 ^@ http://purl.uniprot.org/uniprot/W0F3D4 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/929713:NIASO_RS03415 ^@ http://purl.uniprot.org/uniprot/W0EUQ2 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/929713:NIASO_RS12010 ^@ http://purl.uniprot.org/uniprot/W0F3E4 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/929713:NIASO_RS17310 ^@ http://purl.uniprot.org/uniprot/W0F4A6 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS05680 ^@ http://purl.uniprot.org/uniprot/W0F0J7 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/929713:NIASO_RS19275 ^@ http://purl.uniprot.org/uniprot/W0F1R9 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS06245 ^@ http://purl.uniprot.org/uniprot/W0EZE5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the trans-sulfuration enzymes family. MetZ subfamily.|||Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.|||Homotetramer. http://togogenome.org/gene/929713:NIASO_RS16290 ^@ http://purl.uniprot.org/uniprot/W0F0A1 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum|||Golgi apparatus|||Lysosome|||Secreted http://togogenome.org/gene/929713:NIASO_RS09160 ^@ http://purl.uniprot.org/uniprot/W0F236 ^@ Caution|||Function|||Similarity ^@ Belongs to the GGGP/HepGP synthase family. Group II subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). http://togogenome.org/gene/929713:NIASO_RS09850 ^@ http://purl.uniprot.org/uniprot/W0F2D3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/929713:NIASO_RS11035 ^@ http://purl.uniprot.org/uniprot/W0F2H7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS06865 ^@ http://purl.uniprot.org/uniprot/W0F109 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS07480 ^@ http://purl.uniprot.org/uniprot/W0EWG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS12330 ^@ http://purl.uniprot.org/uniprot/W0EYI0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS18915 ^@ http://purl.uniprot.org/uniprot/W0F619 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS16790 ^@ http://purl.uniprot.org/uniprot/W0F0N3 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/929713:NIASO_RS02640 ^@ http://purl.uniprot.org/uniprot/W0EXX5 ^@ Similarity ^@ Belongs to the UbiD family. http://togogenome.org/gene/929713:NIASO_RS08275 ^@ http://purl.uniprot.org/uniprot/W0F0B5 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/929713:NIASO_RS02205 ^@ http://purl.uniprot.org/uniprot/W0EXR2 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/929713:NIASO_RS13865 ^@ http://purl.uniprot.org/uniprot/W0F450 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS16460 ^@ http://purl.uniprot.org/uniprot/W0F0D6 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/929713:NIASO_RS18300 ^@ http://purl.uniprot.org/uniprot/W0F4T3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS12435 ^@ http://purl.uniprot.org/uniprot/W0EYN5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS09005 ^@ http://purl.uniprot.org/uniprot/W0F1L5 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/929713:NIASO_RS07875 ^@ http://purl.uniprot.org/uniprot/W0EWM5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/929713:NIASO_RS17380 ^@ http://purl.uniprot.org/uniprot/W0F0W1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the KduI family.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. http://togogenome.org/gene/929713:NIASO_RS14485 ^@ http://purl.uniprot.org/uniprot/W0F430 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/929713:NIASO_RS01220 ^@ http://purl.uniprot.org/uniprot/W0EYP6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/929713:NIASO_RS08745 ^@ http://purl.uniprot.org/uniprot/W0F1I3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/929713:NIASO_RS16065 ^@ http://purl.uniprot.org/uniprot/W0F067 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS18470 ^@ http://purl.uniprot.org/uniprot/W0F649 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/929713:NIASO_RS08030 ^@ http://purl.uniprot.org/uniprot/W0F366 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/929713:NIASO_RS00095 ^@ http://purl.uniprot.org/uniprot/W0ET73 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/929713:NIASO_RS06875 ^@ http://purl.uniprot.org/uniprot/W0EZM6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS01070 ^@ http://purl.uniprot.org/uniprot/W0ETV3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/929713:NIASO_RS01505 ^@ http://purl.uniprot.org/uniprot/W0EYI2 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/929713:NIASO_RS14020 ^@ http://purl.uniprot.org/uniprot/W0F2V0 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS00295 ^@ http://purl.uniprot.org/uniprot/W0EWW1 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/929713:NIASO_RS15865 ^@ http://purl.uniprot.org/uniprot/W0F083 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/929713:NIASO_RS07700 ^@ http://purl.uniprot.org/uniprot/W0EWK3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/929713:NIASO_RS11800 ^@ http://purl.uniprot.org/uniprot/W0EYA8 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS00315 ^@ http://purl.uniprot.org/uniprot/W0EY85 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/929713:NIASO_RS13850 ^@ http://purl.uniprot.org/uniprot/W0F7P9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS17135 ^@ http://purl.uniprot.org/uniprot/W0F0P4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase Z family.|||Binds 2 Zn(2+) ions.|||Homodimer.|||Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. http://togogenome.org/gene/929713:NIASO_RS07430 ^@ http://purl.uniprot.org/uniprot/W0F1A2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/929713:NIASO_RS07990 ^@ http://purl.uniprot.org/uniprot/W0F1A1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 2 lipoyl cofactors covalently.|||Forms a 24-polypeptide structural core with octahedral symmetry.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/929713:NIASO_RS12710 ^@ http://purl.uniprot.org/uniprot/W0EYN7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/929713:NIASO_RS05040 ^@ http://purl.uniprot.org/uniprot/W0EVF3 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/929713:NIASO_RS09510 ^@ http://purl.uniprot.org/uniprot/W0EX89 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/929713:NIASO_RS12740 ^@ http://purl.uniprot.org/uniprot/W0EYP2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS16535 ^@ http://purl.uniprot.org/uniprot/W0F3X8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Forms a complex with TatA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. http://togogenome.org/gene/929713:NIASO_RS15510 ^@ http://purl.uniprot.org/uniprot/W0F3J0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS16620 ^@ http://purl.uniprot.org/uniprot/W0F4Z3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.|||Cell inner membrane|||Intake of glucose and galactose.|||Membrane http://togogenome.org/gene/929713:NIASO_RS18155 ^@ http://purl.uniprot.org/uniprot/W0F1A5 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS18795 ^@ http://purl.uniprot.org/uniprot/W0F1J8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/929713:NIASO_RS09810 ^@ http://purl.uniprot.org/uniprot/W0F0X7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS02025 ^@ http://purl.uniprot.org/uniprot/W0EZ19 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/929713:NIASO_RS09830 ^@ http://purl.uniprot.org/uniprot/W0EXJ1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS18120 ^@ http://purl.uniprot.org/uniprot/W0F607 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS05755 ^@ http://purl.uniprot.org/uniprot/W0F095 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Feedback inhibited by histidine. http://togogenome.org/gene/929713:NIASO_RS18115 ^@ http://purl.uniprot.org/uniprot/W0F147 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/929713:NIASO_RS14405 ^@ http://purl.uniprot.org/uniprot/W0EZH7 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/929713:NIASO_RS13030 ^@ http://purl.uniprot.org/uniprot/W0EYX6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/929713:NIASO_RS12655 ^@ http://purl.uniprot.org/uniprot/W0F3N4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/929713:NIASO_RS01095 ^@ http://purl.uniprot.org/uniprot/W0ETV7 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/929713:NIASO_RS10730 ^@ http://purl.uniprot.org/uniprot/W0EXV3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/929713:NIASO_RS14120 ^@ http://purl.uniprot.org/uniprot/W0F464 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS09035 ^@ http://purl.uniprot.org/uniprot/W0F1M0 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/929713:NIASO_RS00700 ^@ http://purl.uniprot.org/uniprot/W0EX22 ^@ Similarity ^@ Belongs to the OprB family. http://togogenome.org/gene/929713:NIASO_RS16465 ^@ http://purl.uniprot.org/uniprot/W0F597 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/929713:NIASO_RS04215 ^@ http://purl.uniprot.org/uniprot/W0EV70 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/929713:NIASO_RS02895 ^@ http://purl.uniprot.org/uniprot/W0EZD8 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/929713:NIASO_RS02220 ^@ http://purl.uniprot.org/uniprot/W0EU57 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic Ku family.|||Homodimer. Interacts with LigD.|||With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. http://togogenome.org/gene/929713:NIASO_RS14065 ^@ http://purl.uniprot.org/uniprot/W0EZ97 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/929713:NIASO_RS18450 ^@ http://purl.uniprot.org/uniprot/W0F5S5 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/929713:NIASO_RS14560 ^@ http://purl.uniprot.org/uniprot/W0F4G4 ^@ Similarity ^@ Belongs to the polysaccharide lyase 8 family. http://togogenome.org/gene/929713:NIASO_RS01680 ^@ http://purl.uniprot.org/uniprot/W0ETY2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 10 (cellulase F) family. http://togogenome.org/gene/929713:NIASO_RS15775 ^@ http://purl.uniprot.org/uniprot/W0F503 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/929713:NIASO_RS03055 ^@ http://purl.uniprot.org/uniprot/W0EZF9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the high-potential iron-sulfur protein (HiPIP) family.|||Homodimer.|||Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria. http://togogenome.org/gene/929713:NIASO_RS11735 ^@ http://purl.uniprot.org/uniprot/W0F1W5 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/929713:NIASO_RS05600 ^@ http://purl.uniprot.org/uniprot/W0F070 ^@ Similarity ^@ Belongs to the SAM hydrolase / SAM-dependent halogenase family. http://togogenome.org/gene/929713:NIASO_RS07385 ^@ http://purl.uniprot.org/uniprot/W0EWF0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 28 family. http://togogenome.org/gene/929713:NIASO_RS02535 ^@ http://purl.uniprot.org/uniprot/W0EUA6 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/929713:NIASO_RS08695 ^@ http://purl.uniprot.org/uniprot/W0F1W3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/929713:NIASO_RS09920 ^@ http://purl.uniprot.org/uniprot/W0EXG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS03120 ^@ http://purl.uniprot.org/uniprot/W0EY45 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/929713:NIASO_RS07060 ^@ http://purl.uniprot.org/uniprot/W0F0T6 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/929713:NIASO_RS11775 ^@ http://purl.uniprot.org/uniprot/W0F3B3 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/929713:NIASO_RS01535 ^@ http://purl.uniprot.org/uniprot/W0EYI4 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/929713:NIASO_RS09420 ^@ http://purl.uniprot.org/uniprot/W0EXC8 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS09320 ^@ http://purl.uniprot.org/uniprot/W0F1R5 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/929713:NIASO_RS18070 ^@ http://purl.uniprot.org/uniprot/W0F144 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/929713:NIASO_RS11160 ^@ http://purl.uniprot.org/uniprot/W0EY32 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/929713:NIASO_RS08700 ^@ http://purl.uniprot.org/uniprot/W0EX20 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/929713:NIASO_RS01900 ^@ http://purl.uniprot.org/uniprot/W0EYM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS06860 ^@ http://purl.uniprot.org/uniprot/W0EW54 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS15255 ^@ http://purl.uniprot.org/uniprot/W0F4D2 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/929713:NIASO_RS15110 ^@ http://purl.uniprot.org/uniprot/W0F4P1 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/929713:NIASO_RS04910 ^@ http://purl.uniprot.org/uniprot/W0F0A2 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/929713:NIASO_RS18060 ^@ http://purl.uniprot.org/uniprot/W0F5M9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS09385 ^@ http://purl.uniprot.org/uniprot/W0EX76 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS05080 ^@ http://purl.uniprot.org/uniprot/W0F009 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/929713:NIASO_RS02000 ^@ http://purl.uniprot.org/uniprot/W0EZ15 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS02805 ^@ http://purl.uniprot.org/uniprot/W0EUI2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/929713:NIASO_RS17915 ^@ http://purl.uniprot.org/uniprot/W0F126 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/929713:NIASO_RS12570 ^@ http://purl.uniprot.org/uniprot/W0F335 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/929713:NIASO_RS16745 ^@ http://purl.uniprot.org/uniprot/W0F508 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS19480 ^@ http://purl.uniprot.org/uniprot/W0F6B1 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/929713:NIASO_RS12375 ^@ http://purl.uniprot.org/uniprot/W0EYM9 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/929713:NIASO_RS00340 ^@ http://purl.uniprot.org/uniprot/W0EY90 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/929713:NIASO_RS10965 ^@ http://purl.uniprot.org/uniprot/W0EY52 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS14610 ^@ http://purl.uniprot.org/uniprot/W0F4H4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS05015 ^@ http://purl.uniprot.org/uniprot/W0EVE9 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/929713:NIASO_RS03430 ^@ http://purl.uniprot.org/uniprot/W0EY91 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/929713:NIASO_RS11050 ^@ http://purl.uniprot.org/uniprot/W0F1L0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS02605 ^@ http://purl.uniprot.org/uniprot/W0EYZ0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 51 family. http://togogenome.org/gene/929713:NIASO_RS02755 ^@ http://purl.uniprot.org/uniprot/W0EUH2 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/929713:NIASO_RS05320 ^@ http://purl.uniprot.org/uniprot/W0EZ33 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS17265 ^@ http://purl.uniprot.org/uniprot/W0F0V5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS18035 ^@ http://purl.uniprot.org/uniprot/W0F5M5 ^@ Similarity ^@ Belongs to the bleomycin resistance protein family. http://togogenome.org/gene/929713:NIASO_RS09885 ^@ http://purl.uniprot.org/uniprot/W0F0Y9 ^@ Similarity|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c. http://togogenome.org/gene/929713:NIASO_RS17480 ^@ http://purl.uniprot.org/uniprot/W0F0X3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/929713:NIASO_RS17880 ^@ http://purl.uniprot.org/uniprot/W0F5K3 ^@ Similarity ^@ Belongs to the RNA polymerase subunit omega family. http://togogenome.org/gene/929713:NIASO_RS02280 ^@ http://purl.uniprot.org/uniprot/W0EUA4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS16505 ^@ http://purl.uniprot.org/uniprot/W0F3X3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/929713:NIASO_RS18505 ^@ http://purl.uniprot.org/uniprot/W0F653 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS12235 ^@ http://purl.uniprot.org/uniprot/W0EYL1 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. http://togogenome.org/gene/929713:NIASO_RS02320 ^@ http://purl.uniprot.org/uniprot/W0EYU1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS12065 ^@ http://purl.uniprot.org/uniprot/H1NJ36 ^@ Similarity ^@ Belongs to the hyi family. http://togogenome.org/gene/929713:NIASO_RS06905 ^@ http://purl.uniprot.org/uniprot/W0EW74 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS12910 ^@ http://purl.uniprot.org/uniprot/W0EYR3 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS15855 ^@ http://purl.uniprot.org/uniprot/W0F032 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/929713:NIASO_RS00145 ^@ http://purl.uniprot.org/uniprot/W0ET78 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/929713:NIASO_RS03790 ^@ http://purl.uniprot.org/uniprot/W0EYE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS12370 ^@ http://purl.uniprot.org/uniprot/W0F417 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS17010 ^@ http://purl.uniprot.org/uniprot/W0F553 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/929713:NIASO_RS06425 ^@ http://purl.uniprot.org/uniprot/W0F0V2 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/929713:NIASO_RS04550 ^@ http://purl.uniprot.org/uniprot/W0EYT9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS08950 ^@ http://purl.uniprot.org/uniprot/W0F1Z9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the arginase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide. http://togogenome.org/gene/929713:NIASO_RS13800 ^@ http://purl.uniprot.org/uniprot/W0F3M0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS14535 ^@ http://purl.uniprot.org/uniprot/W0F4F9 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/929713:NIASO_RS03775 ^@ http://purl.uniprot.org/uniprot/W0EUV6 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS03160 ^@ http://purl.uniprot.org/uniprot/W0EZH2 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/929713:NIASO_RS19150 ^@ http://purl.uniprot.org/uniprot/W0F8F9 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/929713:NIASO_RS07795 ^@ http://purl.uniprot.org/uniprot/W0F171 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/929713:NIASO_RS01365 ^@ http://purl.uniprot.org/uniprot/W0F5I9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS17845 ^@ http://purl.uniprot.org/uniprot/W0F117 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/929713:NIASO_RS13405 ^@ http://purl.uniprot.org/uniprot/W0F2J5 ^@ Similarity ^@ Belongs to the CarB family. http://togogenome.org/gene/929713:NIASO_RS14285 ^@ http://purl.uniprot.org/uniprot/W0F4C3 ^@ Similarity ^@ Belongs to the SIS family. GutQ/KpsF subfamily. http://togogenome.org/gene/929713:NIASO_RS10165 ^@ http://purl.uniprot.org/uniprot/W0F140 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/929713:NIASO_RS01610 ^@ http://purl.uniprot.org/uniprot/W0EXH9 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/929713:NIASO_RS16345 ^@ http://purl.uniprot.org/uniprot/W0F579 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/929713:NIASO_RS18715 ^@ http://purl.uniprot.org/uniprot/W0F692 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS05960 ^@ http://purl.uniprot.org/uniprot/W0F0P0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/929713:NIASO_RS12295 ^@ http://purl.uniprot.org/uniprot/W0EYH5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/929713:NIASO_RS11705 ^@ http://purl.uniprot.org/uniprot/W0F1W0 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS18500 ^@ http://purl.uniprot.org/uniprot/W0F199 ^@ Similarity|||Subunit ^@ Homotetramer.|||In the C-terminal section; belongs to the homoserine dehydrogenase family.|||In the N-terminal section; belongs to the aspartokinase family. http://togogenome.org/gene/929713:NIASO_RS11715 ^@ http://purl.uniprot.org/uniprot/W0EY96 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS08860 ^@ http://purl.uniprot.org/uniprot/W0F1J9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/929713:NIASO_RS15645 ^@ http://purl.uniprot.org/uniprot/W0F4Y5 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS07760 ^@ http://purl.uniprot.org/uniprot/W0F035 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS04020 ^@ http://purl.uniprot.org/uniprot/W0EZV3 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20B family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/929713:NIASO_RS02355 ^@ http://purl.uniprot.org/uniprot/W0EU81 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/929713:NIASO_RS03965 ^@ http://purl.uniprot.org/uniprot/W0EV20 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS04405 ^@ http://purl.uniprot.org/uniprot/W0EZT3 ^@ Similarity ^@ Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. http://togogenome.org/gene/929713:NIASO_RS11905 ^@ http://purl.uniprot.org/uniprot/W0F1Z0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/929713:NIASO_RS12795 ^@ http://purl.uniprot.org/uniprot/W0F3P8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/929713:NIASO_RS15285 ^@ http://purl.uniprot.org/uniprot/W0EZU9 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. http://togogenome.org/gene/929713:NIASO_RS02055 ^@ http://purl.uniprot.org/uniprot/W0EZ24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the urea transporter family.|||Cell membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS09275 ^@ http://purl.uniprot.org/uniprot/W0F258 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 63 family. http://togogenome.org/gene/929713:NIASO_RS06880 ^@ http://purl.uniprot.org/uniprot/W0F0R2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS15900 ^@ http://purl.uniprot.org/uniprot/W0F3Q2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/929713:NIASO_RS14350 ^@ http://purl.uniprot.org/uniprot/W0F4D1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS10880 ^@ http://purl.uniprot.org/uniprot/W0EY26 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS17840 ^@ http://purl.uniprot.org/uniprot/W0F5J8 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/929713:NIASO_RS17005 ^@ http://purl.uniprot.org/uniprot/W0F460 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS13055 ^@ http://purl.uniprot.org/uniprot/W0EYY2 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/929713:NIASO_RS14690 ^@ http://purl.uniprot.org/uniprot/W0EZL8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 30 family. http://togogenome.org/gene/929713:NIASO_RS07225 ^@ http://purl.uniprot.org/uniprot/W0F0W3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.|||Binds 1 Mn(2+) ion per subunit.|||Cytoplasm|||Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS16510 ^@ http://purl.uniprot.org/uniprot/W0F4Y2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/929713:NIASO_RS08770 ^@ http://purl.uniprot.org/uniprot/W0F0I2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS03515 ^@ http://purl.uniprot.org/uniprot/W0EZD1 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS05485 ^@ http://purl.uniprot.org/uniprot/W0F0H2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS12245 ^@ http://purl.uniprot.org/uniprot/W0F241 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/929713:NIASO_RS03375 ^@ http://purl.uniprot.org/uniprot/W0F2H2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/929713:NIASO_RS12805 ^@ http://purl.uniprot.org/uniprot/W0F2B1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/929713:NIASO_RS00120 ^@ http://purl.uniprot.org/uniprot/W0F1R8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/929713:NIASO_RS07815 ^@ http://purl.uniprot.org/uniprot/W0F045 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/929713:NIASO_RS11755 ^@ http://purl.uniprot.org/uniprot/W0EYF9 ^@ Function|||Similarity ^@ Belongs to the RlpA family.|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/929713:NIASO_RS06805 ^@ http://purl.uniprot.org/uniprot/W0F0Q3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS15485 ^@ http://purl.uniprot.org/uniprot/W0F3I4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/929713:NIASO_RS01080 ^@ http://purl.uniprot.org/uniprot/W0EYC1 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/929713:NIASO_RS05435 ^@ http://purl.uniprot.org/uniprot/W0F0G7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS13225 ^@ http://purl.uniprot.org/uniprot/W0F2G5 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Membrane http://togogenome.org/gene/929713:NIASO_RS12700 ^@ http://purl.uniprot.org/uniprot/W0F357 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/929713:NIASO_RS17345 ^@ http://purl.uniprot.org/uniprot/W0F4B9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/929713:NIASO_RS00935 ^@ http://purl.uniprot.org/uniprot/W0EY83 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/929713:NIASO_RS19305 ^@ http://purl.uniprot.org/uniprot/W0F1S4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 28 family. http://togogenome.org/gene/929713:NIASO_RS02065 ^@ http://purl.uniprot.org/uniprot/W0EXQ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreD family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/929713:NIASO_RS15625 ^@ http://purl.uniprot.org/uniprot/W0F043 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/929713:NIASO_RS03970 ^@ http://purl.uniprot.org/uniprot/W0EYI1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS02310 ^@ http://purl.uniprot.org/uniprot/W0EUB0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/929713:NIASO_RS09825 ^@ http://purl.uniprot.org/uniprot/W0F2C8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS14345 ^@ http://purl.uniprot.org/uniprot/W0EZH1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/929713:NIASO_RS07465 ^@ http://purl.uniprot.org/uniprot/W0EWH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS17255 ^@ http://purl.uniprot.org/uniprot/W0F0R6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/929713:NIASO_RS02645 ^@ http://purl.uniprot.org/uniprot/W0EYZ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS06215 ^@ http://purl.uniprot.org/uniprot/W0EZE1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/929713:NIASO_RS08550 ^@ http://purl.uniprot.org/uniprot/W0F1U4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Binds 1 copper ion per subunit, denoted as copper B.|||Binds 2 heme groups per subunit, denoted as high- and low-spin.|||Membrane http://togogenome.org/gene/929713:NIASO_RS12155 ^@ http://purl.uniprot.org/uniprot/W0F228 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS15825 ^@ http://purl.uniprot.org/uniprot/W0F512 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs.|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/929713:NIASO_RS00005 ^@ http://purl.uniprot.org/uniprot/W0ET57 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/929713:NIASO_RS12790 ^@ http://purl.uniprot.org/uniprot/W0EYP8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS08120 ^@ http://purl.uniprot.org/uniprot/W0EWQ7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/929713:NIASO_RS11875 ^@ http://purl.uniprot.org/uniprot/W0EYB8 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. http://togogenome.org/gene/929713:NIASO_RS11300 ^@ http://purl.uniprot.org/uniprot/W0F2L2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS07185 ^@ http://purl.uniprot.org/uniprot/W0F157 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidine kinase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/929713:NIASO_RS03555 ^@ http://purl.uniprot.org/uniprot/W0EUS4 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/929713:NIASO_RS17605 ^@ http://purl.uniprot.org/uniprot/W0F131 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/929713:NIASO_RS07235 ^@ http://purl.uniprot.org/uniprot/W0EWC2 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/929713:NIASO_RS16480 ^@ http://purl.uniprot.org/uniprot/W0F4X7 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/929713:NIASO_RS13845 ^@ http://purl.uniprot.org/uniprot/W0F418 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS07600 ^@ http://purl.uniprot.org/uniprot/W0EWK7 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/929713:NIASO_RS08010 ^@ http://purl.uniprot.org/uniprot/W0EWT1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS07710 ^@ http://purl.uniprot.org/uniprot/W0EWN8 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/929713:NIASO_RS03260 ^@ http://purl.uniprot.org/uniprot/W0F6Z2 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS10435 ^@ http://purl.uniprot.org/uniprot/W0EXQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GRP transporter (TC 2.A.7.5) family.|||Cell membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS14865 ^@ http://purl.uniprot.org/uniprot/W0EZT2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase. http://togogenome.org/gene/929713:NIASO_RS10915 ^@ http://purl.uniprot.org/uniprot/W0F895 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS16960 ^@ http://purl.uniprot.org/uniprot/W0F0L5 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/929713:NIASO_RS17785 ^@ http://purl.uniprot.org/uniprot/W0F110 ^@ Similarity ^@ Belongs to the UPF0502 family. http://togogenome.org/gene/929713:NIASO_RS07885 ^@ http://purl.uniprot.org/uniprot/W0EWR5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/929713:NIASO_RS07255 ^@ http://purl.uniprot.org/uniprot/W0F0W8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS05110 ^@ http://purl.uniprot.org/uniprot/W0F013 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS06375 ^@ http://purl.uniprot.org/uniprot/W0EVY1 ^@ Similarity ^@ Belongs to the peptidase S9A family. http://togogenome.org/gene/929713:NIASO_RS12935 ^@ http://purl.uniprot.org/uniprot/W0F387 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS03435 ^@ http://purl.uniprot.org/uniprot/W0EZC1 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/929713:NIASO_RS03700 ^@ http://purl.uniprot.org/uniprot/W0EUU6 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/929713:NIASO_RS09000 ^@ http://purl.uniprot.org/uniprot/W0F0L3 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/929713:NIASO_RS00630 ^@ http://purl.uniprot.org/uniprot/W0ETL7 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/929713:NIASO_RS09485 ^@ http://purl.uniprot.org/uniprot/W0EXD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS19510 ^@ http://purl.uniprot.org/uniprot/W0F5A6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/929713:NIASO_RS01490 ^@ http://purl.uniprot.org/uniprot/W0EYT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS10675 ^@ http://purl.uniprot.org/uniprot/W0EXU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS16975 ^@ http://purl.uniprot.org/uniprot/W0F0R5 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/929713:NIASO_RS08325 ^@ http://purl.uniprot.org/uniprot/W0EWS9 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/929713:NIASO_RS03620 ^@ http://purl.uniprot.org/uniprot/W0EUT6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/929713:NIASO_RS09230 ^@ http://purl.uniprot.org/uniprot/W0F1Q0 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/929713:NIASO_RS07245 ^@ http://purl.uniprot.org/uniprot/W0EWD6 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/929713:NIASO_RS15195 ^@ http://purl.uniprot.org/uniprot/W0EZY0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS09725 ^@ http://purl.uniprot.org/uniprot/W0F2B5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/929713:NIASO_RS06765 ^@ http://purl.uniprot.org/uniprot/W0F0Z2 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/929713:NIASO_RS02705 ^@ http://purl.uniprot.org/uniprot/W0EXY3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/929713:NIASO_RS02785 ^@ http://purl.uniprot.org/uniprot/W0EXZ5 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/929713:NIASO_RS12275 ^@ http://purl.uniprot.org/uniprot/W0F3I1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/929713:NIASO_RS01290 ^@ http://purl.uniprot.org/uniprot/W0EYQ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS16195 ^@ http://purl.uniprot.org/uniprot/W0F091 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/929713:NIASO_RS17805 ^@ http://purl.uniprot.org/uniprot/W0F4K6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/929713:NIASO_RS19335 ^@ http://purl.uniprot.org/uniprot/W0F1S9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/929713:NIASO_RS17410 ^@ http://purl.uniprot.org/uniprot/W0F5R4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/929713:NIASO_RS04835 ^@ http://purl.uniprot.org/uniprot/W0EZY9 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/929713:NIASO_RS14680 ^@ http://purl.uniprot.org/uniprot/W0F374 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS15515 ^@ http://purl.uniprot.org/uniprot/W0F4H5 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/929713:NIASO_RS00155 ^@ http://purl.uniprot.org/uniprot/W0ETE1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/929713:NIASO_RS06330 ^@ http://purl.uniprot.org/uniprot/W0EVW1 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ 2 residues (Tyr-55 and Arg-58) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.|||Belongs to the sirtuin family. Class III subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. http://togogenome.org/gene/929713:NIASO_RS13895 ^@ http://purl.uniprot.org/uniprot/W0EZB1 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/929713:NIASO_RS00675 ^@ http://purl.uniprot.org/uniprot/W0EY30 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/929713:NIASO_RS05690 ^@ http://purl.uniprot.org/uniprot/W0EZ70 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/929713:NIASO_RS18510 ^@ http://purl.uniprot.org/uniprot/W0F1E7 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/929713:NIASO_RS10315 ^@ http://purl.uniprot.org/uniprot/W0EXT3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/929713:NIASO_RS08210 ^@ http://purl.uniprot.org/uniprot/W0F1P3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/929713:NIASO_RS07835 ^@ http://purl.uniprot.org/uniprot/W0EWQ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/929713:NIASO_RS00940 ^@ http://purl.uniprot.org/uniprot/W0F1X4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS12895 ^@ http://purl.uniprot.org/uniprot/W0F8T0 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS03815 ^@ http://purl.uniprot.org/uniprot/W0F603 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/929713:NIASO_RS13560 ^@ http://purl.uniprot.org/uniprot/W0F3X6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/929713:NIASO_RS09410 ^@ http://purl.uniprot.org/uniprot/W0EX80 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS19420 ^@ http://purl.uniprot.org/uniprot/W0F596 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/929713:NIASO_RS05125 ^@ http://purl.uniprot.org/uniprot/W0EVI0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS00590 ^@ http://purl.uniprot.org/uniprot/W0F203 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/929713:NIASO_RS01805 ^@ http://purl.uniprot.org/uniprot/W0EU40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS03210 ^@ http://purl.uniprot.org/uniprot/W0EZ93 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/929713:NIASO_RS07880 ^@ http://purl.uniprot.org/uniprot/W0F1J5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/929713:NIASO_RS10060 ^@ http://purl.uniprot.org/uniprot/W0F222 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 28 family. http://togogenome.org/gene/929713:NIASO_RS16655 ^@ http://purl.uniprot.org/uniprot/W0F4Z8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS17820 ^@ http://purl.uniprot.org/uniprot/W0F4V0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS11760 ^@ http://purl.uniprot.org/uniprot/W0F1X0 ^@ Domain|||Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.|||Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin. http://togogenome.org/gene/929713:NIASO_RS10400 ^@ http://purl.uniprot.org/uniprot/W0F2M5 ^@ Similarity ^@ Belongs to the phosphosulfolactate synthase family. http://togogenome.org/gene/929713:NIASO_RS11560 ^@ http://purl.uniprot.org/uniprot/W0F2P6 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. http://togogenome.org/gene/929713:NIASO_RS05940 ^@ http://purl.uniprot.org/uniprot/W0EVS1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ApbE family.|||Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.|||Magnesium. Can also use manganese. http://togogenome.org/gene/929713:NIASO_RS18025 ^@ http://purl.uniprot.org/uniprot/W0F187 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS01695 ^@ http://purl.uniprot.org/uniprot/W0EXJ4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/929713:NIASO_RS06585 ^@ http://purl.uniprot.org/uniprot/W0F0W7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS07695 ^@ http://purl.uniprot.org/uniprot/W0F158 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS14495 ^@ http://purl.uniprot.org/uniprot/W0EZI6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS09150 ^@ http://purl.uniprot.org/uniprot/W0F1N7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS00490 ^@ http://purl.uniprot.org/uniprot/W0EY07 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L-fucose isomerase family.|||Converts the aldose L-fucose into the corresponding ketose L-fuculose.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS10350 ^@ http://purl.uniprot.org/uniprot/W0EXT9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL10 family. http://togogenome.org/gene/929713:NIASO_RS16865 ^@ http://purl.uniprot.org/uniprot/W0F530 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS16845 ^@ http://purl.uniprot.org/uniprot/W0F0J5 ^@ Similarity ^@ Belongs to the PAPS reductase family. CysD subfamily. http://togogenome.org/gene/929713:NIASO_RS18095 ^@ http://purl.uniprot.org/uniprot/W0F4Q2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS18210 ^@ http://purl.uniprot.org/uniprot/W0F621 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/929713:NIASO_RS10150 ^@ http://purl.uniprot.org/uniprot/W0EXK4 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/929713:NIASO_RS06695 ^@ http://purl.uniprot.org/uniprot/W0F0N2 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/929713:NIASO_RS17370 ^@ http://purl.uniprot.org/uniprot/W0F4D0 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. http://togogenome.org/gene/929713:NIASO_RS01155 ^@ http://purl.uniprot.org/uniprot/W0ETW6 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/929713:NIASO_RS13650 ^@ http://purl.uniprot.org/uniprot/W0EZ71 ^@ Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. http://togogenome.org/gene/929713:NIASO_RS12120 ^@ http://purl.uniprot.org/uniprot/W0F3F8 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/929713:NIASO_RS09285 ^@ http://purl.uniprot.org/uniprot/W0F0R3 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/929713:NIASO_RS13170 ^@ http://purl.uniprot.org/uniprot/W0EYV5 ^@ Function|||Similarity ^@ Belongs to the HMBS family.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. http://togogenome.org/gene/929713:NIASO_RS14445 ^@ http://purl.uniprot.org/uniprot/W0EZM8 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS01965 ^@ http://purl.uniprot.org/uniprot/W0EU24 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS02455 ^@ http://purl.uniprot.org/uniprot/W0EUD1 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 3 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/929713:NIASO_RS11500 ^@ http://purl.uniprot.org/uniprot/W0F2N9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/929713:NIASO_RS15665 ^@ http://purl.uniprot.org/uniprot/W0F4K0 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. http://togogenome.org/gene/929713:NIASO_RS05165 ^@ http://purl.uniprot.org/uniprot/W0F021 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS05595 ^@ http://purl.uniprot.org/uniprot/W0EZ57 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/929713:NIASO_RS10310 ^@ http://purl.uniprot.org/uniprot/W0F2K8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/929713:NIASO_RS17590 ^@ http://purl.uniprot.org/uniprot/W0F0Y8 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS04620 ^@ http://purl.uniprot.org/uniprot/W0EVC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS18960 ^@ http://purl.uniprot.org/uniprot/W0F1M7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/929713:NIASO_RS14695 ^@ http://purl.uniprot.org/uniprot/W0F4I9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/929713:NIASO_RS08150 ^@ http://purl.uniprot.org/uniprot/W0EWU5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/929713:NIASO_RS13255 ^@ http://purl.uniprot.org/uniprot/W0F3D8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS05230 ^@ http://purl.uniprot.org/uniprot/W0EZ21 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS05860 ^@ http://purl.uniprot.org/uniprot/W0EZA1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/929713:NIASO_RS07635 ^@ http://purl.uniprot.org/uniprot/W0F1G0 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS09305 ^@ http://purl.uniprot.org/uniprot/W0EXA7 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/929713:NIASO_RS05720 ^@ http://purl.uniprot.org/uniprot/W0EZ75 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/929713:NIASO_RS05260 ^@ http://purl.uniprot.org/uniprot/W0F031 ^@ Similarity|||Subunit ^@ Belongs to the KdsC family.|||Homotetramer. http://togogenome.org/gene/929713:NIASO_RS06430 ^@ http://purl.uniprot.org/uniprot/W0EVZ2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/929713:NIASO_RS07165 ^@ http://purl.uniprot.org/uniprot/W0EZR9 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/929713:NIASO_RS16515 ^@ http://purl.uniprot.org/uniprot/W0F0E4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/929713:NIASO_RS17855 ^@ http://purl.uniprot.org/uniprot/W0F887 ^@ Function|||Similarity ^@ Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.|||Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/929713:NIASO_RS00260 ^@ http://purl.uniprot.org/uniprot/W0ETF8 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/929713:NIASO_RS13490 ^@ http://purl.uniprot.org/uniprot/W0EZ49 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/929713:NIASO_RS00885 ^@ http://purl.uniprot.org/uniprot/W0EYH9 ^@ Caution|||Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS01935 ^@ http://purl.uniprot.org/uniprot/W0EU19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS01085 ^@ http://purl.uniprot.org/uniprot/W0ETR4 ^@ Similarity ^@ Belongs to the BshC family. http://togogenome.org/gene/929713:NIASO_RS11370 ^@ http://purl.uniprot.org/uniprot/W0F2M1 ^@ Function ^@ Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. http://togogenome.org/gene/929713:NIASO_RS17105 ^@ http://purl.uniprot.org/uniprot/W0F561 ^@ Similarity ^@ In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the malic enzymes family. http://togogenome.org/gene/929713:NIASO_RS00075 ^@ http://purl.uniprot.org/uniprot/W0EY48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS10265 ^@ http://purl.uniprot.org/uniprot/W0F8B7 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/929713:NIASO_RS01075 ^@ http://purl.uniprot.org/uniprot/W0EXB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS08230 ^@ http://purl.uniprot.org/uniprot/W0EWR8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/929713:NIASO_RS11380 ^@ http://purl.uniprot.org/uniprot/W0F347 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/929713:NIASO_RS06575 ^@ http://purl.uniprot.org/uniprot/W0F0L4 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/929713:NIASO_RS04415 ^@ http://purl.uniprot.org/uniprot/W0F033 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. GalK subfamily.|||Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS04015 ^@ http://purl.uniprot.org/uniprot/W0EV03 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/929713:NIASO_RS15470 ^@ http://purl.uniprot.org/uniprot/W0EZX5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 16 family. http://togogenome.org/gene/929713:NIASO_RS19140 ^@ http://purl.uniprot.org/uniprot/W0F1Q8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/929713:NIASO_RS05140 ^@ http://purl.uniprot.org/uniprot/W0EVG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS10875 ^@ http://purl.uniprot.org/uniprot/W0F2W2 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/929713:NIASO_RS10035 ^@ http://purl.uniprot.org/uniprot/W0F217 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS01420 ^@ http://purl.uniprot.org/uniprot/W0EYG9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/929713:NIASO_RS07520 ^@ http://purl.uniprot.org/uniprot/W0EWI6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/929713:NIASO_RS06710 ^@ http://purl.uniprot.org/uniprot/W0EW40 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/929713:NIASO_RS10610 ^@ http://purl.uniprot.org/uniprot/W0F1B0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 16 family. http://togogenome.org/gene/929713:NIASO_RS00880 ^@ http://purl.uniprot.org/uniprot/W0ETK7 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/929713:NIASO_RS09105 ^@ http://purl.uniprot.org/uniprot/W0EX74 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS08360 ^@ http://purl.uniprot.org/uniprot/W0F1S1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/929713:NIASO_RS10520 ^@ http://purl.uniprot.org/uniprot/W0EXW2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS14990 ^@ http://purl.uniprot.org/uniprot/W0F3B7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS17195 ^@ http://purl.uniprot.org/uniprot/W0F5L9 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/929713:NIASO_RS09575 ^@ http://purl.uniprot.org/uniprot/W0F0U5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpC family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/929713:NIASO_RS06310 ^@ http://purl.uniprot.org/uniprot/W0EZF3 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/929713:NIASO_RS00545 ^@ http://purl.uniprot.org/uniprot/W0EYC0 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/929713:NIASO_RS11975 ^@ http://purl.uniprot.org/uniprot/W0F201 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/929713:NIASO_RS00605 ^@ http://purl.uniprot.org/uniprot/W0ETL4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS00820 ^@ http://purl.uniprot.org/uniprot/W0ETP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS07240 ^@ http://purl.uniprot.org/uniprot/W0F169 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/929713:NIASO_RS16300 ^@ http://purl.uniprot.org/uniprot/W0F0E9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS05785 ^@ http://purl.uniprot.org/uniprot/W0EVP2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS00920 ^@ http://purl.uniprot.org/uniprot/W0EYJ4 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/929713:NIASO_RS09380 ^@ http://purl.uniprot.org/uniprot/W0F1S5 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/929713:NIASO_RS08155 ^@ http://purl.uniprot.org/uniprot/W0F093 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/929713:NIASO_RS08910 ^@ http://purl.uniprot.org/uniprot/W0F0J9 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/929713:NIASO_RS14925 ^@ http://purl.uniprot.org/uniprot/W0F3A6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS00510 ^@ http://purl.uniprot.org/uniprot/W0ETK3 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS13050 ^@ http://purl.uniprot.org/uniprot/W0F3R8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/929713:NIASO_RS10590 ^@ http://purl.uniprot.org/uniprot/W0F291 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS01395 ^@ http://purl.uniprot.org/uniprot/W0EYG5 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/929713:NIASO_RS17970 ^@ http://purl.uniprot.org/uniprot/W0F132 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/929713:NIASO_RS08800 ^@ http://purl.uniprot.org/uniprot/W0F0I7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS13235 ^@ http://purl.uniprot.org/uniprot/W0EYW5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Binds a copper A center.|||Cell membrane|||Membrane|||Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). http://togogenome.org/gene/929713:NIASO_RS15815 ^@ http://purl.uniprot.org/uniprot/W0F4M5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS01415 ^@ http://purl.uniprot.org/uniprot/W0EXF5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS04615 ^@ http://purl.uniprot.org/uniprot/W0F069 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS10270 ^@ http://purl.uniprot.org/uniprot/W0F156 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/929713:NIASO_RS11420 ^@ http://purl.uniprot.org/uniprot/W0EYA7 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/929713:NIASO_RS15020 ^@ http://purl.uniprot.org/uniprot/W0F3B9 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/929713:NIASO_RS14230 ^@ http://purl.uniprot.org/uniprot/W0EZD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS15610 ^@ http://purl.uniprot.org/uniprot/W0F4J0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS06415 ^@ http://purl.uniprot.org/uniprot/W0EVX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS07945 ^@ http://purl.uniprot.org/uniprot/W0EWN2 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/929713:NIASO_RS10645 ^@ http://purl.uniprot.org/uniprot/W0F2A1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/929713:NIASO_RS03455 ^@ http://purl.uniprot.org/uniprot/W0EY97 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/929713:NIASO_RS03730 ^@ http://purl.uniprot.org/uniprot/W0EUV1 ^@ PTM|||Similarity|||Subunit ^@ Belongs to the gamma-glutamyltransferase family.|||Cleaved by autocatalysis into a large and a small subunit.|||This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide. http://togogenome.org/gene/929713:NIASO_RS08705 ^@ http://purl.uniprot.org/uniprot/W0F0G8 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/929713:NIASO_RS04790 ^@ http://purl.uniprot.org/uniprot/W0F087 ^@ Similarity ^@ Belongs to the DNA polymerase type-Y family. http://togogenome.org/gene/929713:NIASO_RS11070 ^@ http://purl.uniprot.org/uniprot/W0EY19 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/929713:NIASO_RS09515 ^@ http://purl.uniprot.org/uniprot/W0F289 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/929713:NIASO_RS02575 ^@ http://purl.uniprot.org/uniprot/W0EXW6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 39 family. http://togogenome.org/gene/929713:NIASO_RS00070 ^@ http://purl.uniprot.org/uniprot/W0ET67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0382 family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS10890 ^@ http://purl.uniprot.org/uniprot/W0F2E0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS01210 ^@ http://purl.uniprot.org/uniprot/W0EYD8 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated Cas9 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.|||Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.|||Monomer. Binds crRNA and tracrRNA. http://togogenome.org/gene/929713:NIASO_RS19500 ^@ http://purl.uniprot.org/uniprot/W0F6K4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueG family.|||Binds 2 [4Fe-4S] clusters per monomer.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/929713:NIASO_RS13840 ^@ http://purl.uniprot.org/uniprot/W0EZ62 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/929713:NIASO_RS16870 ^@ http://purl.uniprot.org/uniprot/W0F0K1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS02005 ^@ http://purl.uniprot.org/uniprot/W0EU74 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS06895 ^@ http://purl.uniprot.org/uniprot/W0F310 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS10715 ^@ http://purl.uniprot.org/uniprot/W0EXZ6 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/929713:NIASO_RS11025 ^@ http://purl.uniprot.org/uniprot/W0EY60 ^@ Similarity ^@ Belongs to the peptidase S51 family. http://togogenome.org/gene/929713:NIASO_RS12485 ^@ http://purl.uniprot.org/uniprot/W0F3L7 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/929713:NIASO_RS07775 ^@ http://purl.uniprot.org/uniprot/W0EWL2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/929713:NIASO_RS16755 ^@ http://purl.uniprot.org/uniprot/W0F5D5 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/929713:NIASO_RS17530 ^@ http://purl.uniprot.org/uniprot/W0F0Y2 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/929713:NIASO_RS18790 ^@ http://purl.uniprot.org/uniprot/W0F6A6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS03985 ^@ http://purl.uniprot.org/uniprot/W0EUZ6 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/929713:NIASO_RS15265 ^@ http://purl.uniprot.org/uniprot/W0F4S0 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/929713:NIASO_RS14920 ^@ http://purl.uniprot.org/uniprot/W0EZU1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/929713:NIASO_RS15655 ^@ http://purl.uniprot.org/uniprot/W0F3L6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS00115 ^@ http://purl.uniprot.org/uniprot/W0EWT5 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS13765 ^@ http://purl.uniprot.org/uniprot/W0EZ89 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/929713:NIASO_RS14970 ^@ http://purl.uniprot.org/uniprot/W0F495 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/929713:NIASO_RS13090 ^@ http://purl.uniprot.org/uniprot/W0F461 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS16325 ^@ http://purl.uniprot.org/uniprot/W0F0F5 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/929713:NIASO_RS12045 ^@ http://purl.uniprot.org/uniprot/W0F3F0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS02700 ^@ http://purl.uniprot.org/uniprot/W0EUG1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/929713:NIASO_RS01355 ^@ http://purl.uniprot.org/uniprot/W0EYF8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HisA/HisF family.|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/929713:NIASO_RS11205 ^@ http://purl.uniprot.org/uniprot/W0F322 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/929713:NIASO_RS16775 ^@ http://purl.uniprot.org/uniprot/W0F513 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS06475 ^@ http://purl.uniprot.org/uniprot/W0EVZ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/929713:NIASO_RS19095 ^@ http://purl.uniprot.org/uniprot/W0F655 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/929713:NIASO_RS02485 ^@ http://purl.uniprot.org/uniprot/W0EUD5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS09500 ^@ http://purl.uniprot.org/uniprot/W0F1U1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS02795 ^@ http://purl.uniprot.org/uniprot/W0EUE7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS04040 ^@ http://purl.uniprot.org/uniprot/W0EV08 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/929713:NIASO_RS05275 ^@ http://purl.uniprot.org/uniprot/W0F0F3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/929713:NIASO_RS04295 ^@ http://purl.uniprot.org/uniprot/W0EZR6 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/929713:NIASO_RS15555 ^@ http://purl.uniprot.org/uniprot/W0F4X0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell inner membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/929713:NIASO_RS11295 ^@ http://purl.uniprot.org/uniprot/W0F1P5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/929713:NIASO_RS13135 ^@ http://purl.uniprot.org/uniprot/W0EYU9 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/929713:NIASO_RS02760 ^@ http://purl.uniprot.org/uniprot/W0EXZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS14375 ^@ http://purl.uniprot.org/uniprot/W0F4D5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS16910 ^@ http://purl.uniprot.org/uniprot/W0F5G1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS12685 ^@ http://purl.uniprot.org/uniprot/W0EYS7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/929713:NIASO_RS11815 ^@ http://purl.uniprot.org/uniprot/W0F7D0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/929713:NIASO_RS00180 ^@ http://purl.uniprot.org/uniprot/W0ET83 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS04560 ^@ http://purl.uniprot.org/uniprot/W0EVA0 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/929713:NIASO_RS01065 ^@ http://purl.uniprot.org/uniprot/W0EYM6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/929713:NIASO_RS04205 ^@ http://purl.uniprot.org/uniprot/W0EZZ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS03580 ^@ http://purl.uniprot.org/uniprot/W0EUT0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/929713:NIASO_RS10285 ^@ http://purl.uniprot.org/uniprot/W0EXM7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/929713:NIASO_RS14855 ^@ http://purl.uniprot.org/uniprot/W0EZN3 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/929713:NIASO_RS18270 ^@ http://purl.uniprot.org/uniprot/W0F4S8 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/929713:NIASO_RS06685 ^@ http://purl.uniprot.org/uniprot/W0EZJ5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS11695 ^@ http://purl.uniprot.org/uniprot/W0F3A0 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/929713:NIASO_RS04050 ^@ http://purl.uniprot.org/uniprot/W0EV35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS05105 ^@ http://purl.uniprot.org/uniprot/W0F2P9 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/929713:NIASO_RS00765 ^@ http://purl.uniprot.org/uniprot/W0EX33 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/929713:NIASO_RS19000 ^@ http://purl.uniprot.org/uniprot/W0F547 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS16955 ^@ http://purl.uniprot.org/uniprot/W0F543 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/929713:NIASO_RS09065 ^@ http://purl.uniprot.org/uniprot/W0F1M5 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/929713:NIASO_RS08250 ^@ http://purl.uniprot.org/uniprot/W0F1D5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Cell membrane|||Membrane|||Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. http://togogenome.org/gene/929713:NIASO_RS07215 ^@ http://purl.uniprot.org/uniprot/W0EWC9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/929713:NIASO_RS14620 ^@ http://purl.uniprot.org/uniprot/W0EZQ1 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/929713:NIASO_RS01755 ^@ http://purl.uniprot.org/uniprot/W0EXK1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS04555 ^@ http://purl.uniprot.org/uniprot/W0EZV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS09490 ^@ http://purl.uniprot.org/uniprot/W0F0T9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS07850 ^@ http://purl.uniprot.org/uniprot/W0EWM2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/929713:NIASO_RS01100 ^@ http://purl.uniprot.org/uniprot/W0EXB6 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/929713:NIASO_RS13445 ^@ http://purl.uniprot.org/uniprot/W0EYZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS10690 ^@ http://purl.uniprot.org/uniprot/W0F1C8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/929713:NIASO_RS08225 ^@ http://purl.uniprot.org/uniprot/W0F0A4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/929713:NIASO_RS18355 ^@ http://purl.uniprot.org/uniprot/W0F4T7 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/929713:NIASO_RS11910 ^@ http://purl.uniprot.org/uniprot/W0F2U3 ^@ Similarity ^@ Belongs to the HSP15 family. http://togogenome.org/gene/929713:NIASO_RS17180 ^@ http://purl.uniprot.org/uniprot/W0F0U0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/929713:NIASO_RS07845 ^@ http://purl.uniprot.org/uniprot/W0F178 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/929713:NIASO_RS13945 ^@ http://purl.uniprot.org/uniprot/W0EZ76 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 28 family. http://togogenome.org/gene/929713:NIASO_RS05950 ^@ http://purl.uniprot.org/uniprot/W0F0C2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/929713:NIASO_RS01520 ^@ http://purl.uniprot.org/uniprot/W0EYU2 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/929713:NIASO_RS14110 ^@ http://purl.uniprot.org/uniprot/W0F457 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/929713:NIASO_RS06015 ^@ http://purl.uniprot.org/uniprot/W0F0P6 ^@ Similarity ^@ Belongs to the Lgt family. http://togogenome.org/gene/929713:NIASO_RS10425 ^@ http://purl.uniprot.org/uniprot/W0F276 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/929713:NIASO_RS11045 ^@ http://purl.uniprot.org/uniprot/W0EY64 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/929713:NIASO_RS05020 ^@ http://purl.uniprot.org/uniprot/W0F0B7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS07970 ^@ http://purl.uniprot.org/uniprot/W0EWN7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/929713:NIASO_RS02725 ^@ http://purl.uniprot.org/uniprot/W0EUG7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/929713:NIASO_RS00055 ^@ http://purl.uniprot.org/uniprot/W0ETC5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/929713:NIASO_RS12840 ^@ http://purl.uniprot.org/uniprot/W0EYV2 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS03190 ^@ http://purl.uniprot.org/uniprot/W0EUL9 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS07460 ^@ http://purl.uniprot.org/uniprot/W0F1A8 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS08640 ^@ http://purl.uniprot.org/uniprot/W0F0F9 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/929713:NIASO_RS05030 ^@ http://purl.uniprot.org/uniprot/W0EYZ8 ^@ Caution|||Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS03345 ^@ http://purl.uniprot.org/uniprot/W0F783 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/929713:NIASO_RS09870 ^@ http://purl.uniprot.org/uniprot/W0EXE9 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/929713:NIASO_RS13625 ^@ http://purl.uniprot.org/uniprot/W0F3J1 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/929713:NIASO_RS06615 ^@ http://purl.uniprot.org/uniprot/W0EW08 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS10660 ^@ http://purl.uniprot.org/uniprot/W0EXY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS04140 ^@ http://purl.uniprot.org/uniprot/W0EZW8 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/929713:NIASO_RS16550 ^@ http://purl.uniprot.org/uniprot/W0F5A9 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/929713:NIASO_RS01045 ^@ http://purl.uniprot.org/uniprot/W0ETU6 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/929713:NIASO_RS00015 ^@ http://purl.uniprot.org/uniprot/W0EY38 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/929713:NIASO_RS02635 ^@ http://purl.uniprot.org/uniprot/W0EUF1 ^@ Cofactor|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/929713:NIASO_RS12660 ^@ http://purl.uniprot.org/uniprot/W0EYS3 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/929713:NIASO_RS05955 ^@ http://purl.uniprot.org/uniprot/W0EVR5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/929713:NIASO_RS00620 ^@ http://purl.uniprot.org/uniprot/W0ETG0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS02075 ^@ http://purl.uniprot.org/uniprot/W0EU42 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreF family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/929713:NIASO_RS14070 ^@ http://purl.uniprot.org/uniprot/W0F452 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS15820 ^@ http://purl.uniprot.org/uniprot/W0F027 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS08235 ^@ http://purl.uniprot.org/uniprot/W0F1P9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/929713:NIASO_RS13270 ^@ http://purl.uniprot.org/uniprot/W0EZ18 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS01985 ^@ http://purl.uniprot.org/uniprot/W0EYP3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/929713:NIASO_RS15945 ^@ http://purl.uniprot.org/uniprot/W0F046 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS02850 ^@ http://purl.uniprot.org/uniprot/W0EUF8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS10360 ^@ http://purl.uniprot.org/uniprot/W0F265 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/929713:NIASO_RS12930 ^@ http://purl.uniprot.org/uniprot/W0F2C5 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS00755 ^@ http://purl.uniprot.org/uniprot/W0EYF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/929713:NIASO_RS10695 ^@ http://purl.uniprot.org/uniprot/W0F2A9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/929713:NIASO_RS14060 ^@ http://purl.uniprot.org/uniprot/W0F8Z7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS17365 ^@ http://purl.uniprot.org/uniprot/W0F0Z9 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/929713:NIASO_RS19485 ^@ http://purl.uniprot.org/uniprot/W0F1Q7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS00185 ^@ http://purl.uniprot.org/uniprot/W0EY68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS18860 ^@ http://purl.uniprot.org/uniprot/W0F606 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/929713:NIASO_RS17955 ^@ http://purl.uniprot.org/uniprot/W0F177 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/929713:NIASO_RS13930 ^@ http://purl.uniprot.org/uniprot/W0EZB6 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/929713:NIASO_RS18215 ^@ http://purl.uniprot.org/uniprot/W0F1B3 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/929713:NIASO_RS00635 ^@ http://purl.uniprot.org/uniprot/W0EX12 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/929713:NIASO_RS08085 ^@ http://purl.uniprot.org/uniprot/W0F1B5 ^@ Similarity ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. http://togogenome.org/gene/929713:NIASO_RS08240 ^@ http://purl.uniprot.org/uniprot/W0EWV7 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/929713:NIASO_RS18780 ^@ http://purl.uniprot.org/uniprot/W0F5Y7 ^@ Similarity ^@ Belongs to the four-carbon acid sugar kinase family. http://togogenome.org/gene/929713:NIASO_RS05665 ^@ http://purl.uniprot.org/uniprot/W0EZ65 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/929713:NIASO_RS16895 ^@ http://purl.uniprot.org/uniprot/W0F536 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/929713:NIASO_RS07205 ^@ http://purl.uniprot.org/uniprot/W0EWB7 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/929713:NIASO_RS15880 ^@ http://purl.uniprot.org/uniprot/W0F036 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS03380 ^@ http://purl.uniprot.org/uniprot/W0EZB3 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/929713:NIASO_RS08845 ^@ http://purl.uniprot.org/uniprot/W0EX43 ^@ Cofactor|||Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/929713:NIASO_RS03845 ^@ http://purl.uniprot.org/uniprot/W0EUZ9 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS13200 ^@ http://purl.uniprot.org/uniprot/W0F3C7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HemJ family.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/929713:NIASO_RS05775 ^@ http://purl.uniprot.org/uniprot/W0EZ85 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/929713:NIASO_RS11260 ^@ http://purl.uniprot.org/uniprot/W0EY40 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS14465 ^@ http://purl.uniprot.org/uniprot/W0EZI5 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/929713:NIASO_RS12350 ^@ http://purl.uniprot.org/uniprot/W0F253 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/929713:NIASO_RS14035 ^@ http://purl.uniprot.org/uniprot/W0F447 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS02430 ^@ http://purl.uniprot.org/uniprot/W0EXU9 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/929713:NIASO_RS16010 ^@ http://purl.uniprot.org/uniprot/W0F0A6 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/929713:NIASO_RS13970 ^@ http://purl.uniprot.org/uniprot/W0F3P7 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS15120 ^@ http://purl.uniprot.org/uniprot/W0F3C8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS08190 ^@ http://purl.uniprot.org/uniprot/W0F098 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS06855 ^@ http://purl.uniprot.org/uniprot/W0F324 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS15650 ^@ http://purl.uniprot.org/uniprot/W0F048 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/929713:NIASO_RS02530 ^@ http://purl.uniprot.org/uniprot/W0EYX8 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS12585 ^@ http://purl.uniprot.org/uniprot/W0EYR1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/929713:NIASO_RS13890 ^@ http://purl.uniprot.org/uniprot/W0F422 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS04740 ^@ http://purl.uniprot.org/uniprot/W0EYV9 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/929713:NIASO_RS13180 ^@ http://purl.uniprot.org/uniprot/W0EZ02 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS10560 ^@ http://purl.uniprot.org/uniprot/W0F198 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS06450 ^@ http://purl.uniprot.org/uniprot/W0EVY4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NRAMP family.|||Cell membrane|||H(+)-stimulated, divalent metal cation uptake system.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS07870 ^@ http://purl.uniprot.org/uniprot/W0F183 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/929713:NIASO_RS17535 ^@ http://purl.uniprot.org/uniprot/W0F5T0 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/929713:NIASO_RS10565 ^@ http://purl.uniprot.org/uniprot/W0F288 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS18675 ^@ http://purl.uniprot.org/uniprot/W0F4Z4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS16855 ^@ http://purl.uniprot.org/uniprot/W0F0P5 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Belongs to the peroxiredoxin family. Prx6 subfamily. http://togogenome.org/gene/929713:NIASO_RS05935 ^@ http://purl.uniprot.org/uniprot/W0F0N5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/929713:NIASO_RS18580 ^@ http://purl.uniprot.org/uniprot/W0F1B2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/929713:NIASO_RS14130 ^@ http://purl.uniprot.org/uniprot/W0F2W4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/929713:NIASO_RS17945 ^@ http://purl.uniprot.org/uniprot/W0F5Y9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/929713:NIASO_RS14075 ^@ http://purl.uniprot.org/uniprot/W0EZE3 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS15550 ^@ http://purl.uniprot.org/uniprot/W0EZY8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/929713:NIASO_RS11385 ^@ http://purl.uniprot.org/uniprot/W0EYA3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/929713:NIASO_RS18555 ^@ http://purl.uniprot.org/uniprot/W0F1A7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 28 family. http://togogenome.org/gene/929713:NIASO_RS01970 ^@ http://purl.uniprot.org/uniprot/W0EZ10 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/929713:NIASO_RS13230 ^@ http://purl.uniprot.org/uniprot/W0F3D1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS14950 ^@ http://purl.uniprot.org/uniprot/W0EZU6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the vitamin-B12 independent methionine synthase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation. http://togogenome.org/gene/929713:NIASO_RS05765 ^@ http://purl.uniprot.org/uniprot/W0F0L0 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS00165 ^@ http://purl.uniprot.org/uniprot/W0EWU0 ^@ Similarity ^@ Belongs to the bleomycin resistance protein family. http://togogenome.org/gene/929713:NIASO_RS07680 ^@ http://purl.uniprot.org/uniprot/W0EWN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS12255 ^@ http://purl.uniprot.org/uniprot/W0EYG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/929713:NIASO_RS03605 ^@ http://purl.uniprot.org/uniprot/W0EUW3 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/929713:NIASO_RS08450 ^@ http://purl.uniprot.org/uniprot/W0EWT9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/929713:NIASO_RS05795 ^@ http://purl.uniprot.org/uniprot/W0EVQ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/929713:NIASO_RS12040 ^@ http://purl.uniprot.org/uniprot/W0EYD6 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/929713:NIASO_RS16740 ^@ http://purl.uniprot.org/uniprot/W0F410 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS00110 ^@ http://purl.uniprot.org/uniprot/W0ETD6 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/929713:NIASO_RS06070 ^@ http://purl.uniprot.org/uniprot/W0EVU1 ^@ Similarity ^@ Belongs to the glycosyltransferase 1 family. http://togogenome.org/gene/929713:NIASO_RS06650 ^@ http://purl.uniprot.org/uniprot/W0EW28 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/929713:NIASO_RS07780 ^@ http://purl.uniprot.org/uniprot/W0F1H9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/929713:NIASO_RS07940 ^@ http://purl.uniprot.org/uniprot/W0F192 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/929713:NIASO_RS02610 ^@ http://purl.uniprot.org/uniprot/W0EUB8 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/929713:NIASO_RS12640 ^@ http://purl.uniprot.org/uniprot/W0F346 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/929713:NIASO_RS16565 ^@ http://purl.uniprot.org/uniprot/W0F0J6 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/929713:NIASO_RS13145 ^@ http://purl.uniprot.org/uniprot/W0EYZ7 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/929713:NIASO_RS09835 ^@ http://purl.uniprot.org/uniprot/W0F0Y1 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/929713:NIASO_RS10115 ^@ http://purl.uniprot.org/uniprot/W0F230 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/929713:NIASO_RS18170 ^@ http://purl.uniprot.org/uniprot/W0F154 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS03625 ^@ http://purl.uniprot.org/uniprot/W0EZN8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/929713:NIASO_RS12665 ^@ http://purl.uniprot.org/uniprot/W0F295 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS02900 ^@ http://purl.uniprot.org/uniprot/W0EUJ6 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/929713:NIASO_RS02590 ^@ http://purl.uniprot.org/uniprot/W0EZ95 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 27 family. http://togogenome.org/gene/929713:NIASO_RS17305 ^@ http://purl.uniprot.org/uniprot/W0F0W0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS17020 ^@ http://purl.uniprot.org/uniprot/W0F5I4 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/929713:NIASO_RS03870 ^@ http://purl.uniprot.org/uniprot/W0EV05 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/929713:NIASO_RS13415 ^@ http://purl.uniprot.org/uniprot/W0EYZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS00440 ^@ http://purl.uniprot.org/uniprot/W0ETD2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS11750 ^@ http://purl.uniprot.org/uniprot/W0F3B0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS15350 ^@ http://purl.uniprot.org/uniprot/W0EZV6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS15605 ^@ http://purl.uniprot.org/uniprot/W0F3K7 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS13020 ^@ http://purl.uniprot.org/uniprot/W0EYS9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/929713:NIASO_RS18285 ^@ http://purl.uniprot.org/uniprot/W0F170 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. http://togogenome.org/gene/929713:NIASO_RS02085 ^@ http://purl.uniprot.org/uniprot/W0EU84 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.|||Binds 2 nickel ions per subunit.|||Carbamylation allows a single lysine to coordinate two nickel ions.|||Carboxylation allows a single lysine to coordinate two nickel ions.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/929713:NIASO_RS06705 ^@ http://purl.uniprot.org/uniprot/W0F0Y3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS09755 ^@ http://purl.uniprot.org/uniprot/W0F2B9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/929713:NIASO_RS18840 ^@ http://purl.uniprot.org/uniprot/W0F6B7 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/929713:NIASO_RS10470 ^@ http://purl.uniprot.org/uniprot/W0F279 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/929713:NIASO_RS16850 ^@ http://purl.uniprot.org/uniprot/W0F5F2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS09040 ^@ http://purl.uniprot.org/uniprot/W0EX21 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/929713:NIASO_RS08755 ^@ http://purl.uniprot.org/uniprot/W0EWX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS18220 ^@ http://purl.uniprot.org/uniprot/W0F4S2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/929713:NIASO_RS11390 ^@ http://purl.uniprot.org/uniprot/W0F1R0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/929713:NIASO_RS01120 ^@ http://purl.uniprot.org/uniprot/W0ETW2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/929713:NIASO_RS15750 ^@ http://purl.uniprot.org/uniprot/W0F3N0 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/929713:NIASO_RS04895 ^@ http://purl.uniprot.org/uniprot/W0EZZ2 ^@ Function ^@ Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. http://togogenome.org/gene/929713:NIASO_RS18370 ^@ http://purl.uniprot.org/uniprot/W0F636 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS16085 ^@ http://purl.uniprot.org/uniprot/W0F3S4 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/929713:NIASO_RS04200 ^@ http://purl.uniprot.org/uniprot/W0EV44 ^@ Caution|||Function|||Similarity ^@ Belongs to the LpxK family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). http://togogenome.org/gene/929713:NIASO_RS08995 ^@ http://purl.uniprot.org/uniprot/W0EX59 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/929713:NIASO_RS08970 ^@ http://purl.uniprot.org/uniprot/W0EX11 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/929713:NIASO_RS10345 ^@ http://purl.uniprot.org/uniprot/W0F2L5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/929713:NIASO_RS07800 ^@ http://purl.uniprot.org/uniprot/W0EWL6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/929713:NIASO_RS16700 ^@ http://purl.uniprot.org/uniprot/W0F0L8 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/929713:NIASO_RS17485 ^@ http://purl.uniprot.org/uniprot/W0F5S2 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/929713:NIASO_RS09610 ^@ http://purl.uniprot.org/uniprot/W0F1V3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS04445 ^@ http://purl.uniprot.org/uniprot/W0F038 ^@ Similarity ^@ Belongs to the AIR synthase family. http://togogenome.org/gene/929713:NIASO_RS07915 ^@ http://purl.uniprot.org/uniprot/W0F188 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS17325 ^@ http://purl.uniprot.org/uniprot/W0F4S6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 28 family. http://togogenome.org/gene/929713:NIASO_RS07025 ^@ http://purl.uniprot.org/uniprot/W0EZP3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS08600 ^@ http://purl.uniprot.org/uniprot/W0F0F4 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/929713:NIASO_RS09345 ^@ http://purl.uniprot.org/uniprot/W0EXB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS09585 ^@ http://purl.uniprot.org/uniprot/W0EX99 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpA family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/929713:NIASO_RS09295 ^@ http://purl.uniprot.org/uniprot/W0EX64 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/929713:NIASO_RS00445 ^@ http://purl.uniprot.org/uniprot/W0EYA5 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/929713:NIASO_RS06120 ^@ http://purl.uniprot.org/uniprot/W0EVT7 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/929713:NIASO_RS17475 ^@ http://purl.uniprot.org/uniprot/W0F5E6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/929713:NIASO_RS15785 ^@ http://purl.uniprot.org/uniprot/W0F3N5 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/929713:NIASO_RS07035 ^@ http://purl.uniprot.org/uniprot/W0EW83 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/929713:NIASO_RS15445 ^@ http://purl.uniprot.org/uniprot/W0EZX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS19455 ^@ http://purl.uniprot.org/uniprot/W0F6A5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS13670 ^@ http://purl.uniprot.org/uniprot/W0F3Z1 ^@ Function|||Similarity ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. http://togogenome.org/gene/929713:NIASO_RS20475 ^@ http://purl.uniprot.org/uniprot/W0EXQ3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease beta subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/929713:NIASO_RS10075 ^@ http://purl.uniprot.org/uniprot/W0EXP2 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS12135 ^@ http://purl.uniprot.org/uniprot/W0F2W9 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/929713:NIASO_RS06870 ^@ http://purl.uniprot.org/uniprot/W0EW69 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS18735 ^@ http://purl.uniprot.org/uniprot/H1NKL3 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/929713:NIASO_RS13860 ^@ http://purl.uniprot.org/uniprot/W0EZA4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/929713:NIASO_RS18110 ^@ http://purl.uniprot.org/uniprot/W0F5N3 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/929713:NIASO_RS02685 ^@ http://purl.uniprot.org/uniprot/W0EZA7 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/929713:NIASO_RS06950 ^@ http://purl.uniprot.org/uniprot/W0EW72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LPG synthase family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS01880 ^@ http://purl.uniprot.org/uniprot/W0EU09 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS04515 ^@ http://purl.uniprot.org/uniprot/W0F049 ^@ PTM ^@ The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/929713:NIASO_RS07010 ^@ http://purl.uniprot.org/uniprot/W0EW78 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/929713:NIASO_RS10600 ^@ http://purl.uniprot.org/uniprot/W0F2Q2 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/929713:NIASO_RS13485 ^@ http://purl.uniprot.org/uniprot/W0F3W7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/929713:NIASO_RS10245 ^@ http://purl.uniprot.org/uniprot/W0EXM2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS01495 ^@ http://purl.uniprot.org/uniprot/W0EU02 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/929713:NIASO_RS18195 ^@ http://purl.uniprot.org/uniprot/W0F5P7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/929713:NIASO_RS04195 ^@ http://purl.uniprot.org/uniprot/W0EZP1 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/929713:NIASO_RS04965 ^@ http://purl.uniprot.org/uniprot/W0F0A7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/929713:NIASO_RS18160 ^@ http://purl.uniprot.org/uniprot/W0F4R2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS15040 ^@ http://purl.uniprot.org/uniprot/W0F947 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/929713:NIASO_RS06075 ^@ http://purl.uniprot.org/uniprot/W0EZD0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/929713:NIASO_RS17960 ^@ http://purl.uniprot.org/uniprot/W0F4N2 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/929713:NIASO_RS08915 ^@ http://purl.uniprot.org/uniprot/W0F1K3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/929713:NIASO_RS13035 ^@ http://purl.uniprot.org/uniprot/W0F2D6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/929713:NIASO_RS01665 ^@ http://purl.uniprot.org/uniprot/W0EU20 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS09250 ^@ http://purl.uniprot.org/uniprot/W0EX97 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS07750 ^@ http://purl.uniprot.org/uniprot/W0EWP3 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/929713:NIASO_RS15535 ^@ http://purl.uniprot.org/uniprot/W0F3J6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 130 family. http://togogenome.org/gene/929713:NIASO_RS12515 ^@ http://purl.uniprot.org/uniprot/W0F3L9 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/929713:NIASO_RS13575 ^@ http://purl.uniprot.org/uniprot/W0F2M3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS00090 ^@ http://purl.uniprot.org/uniprot/W0EXV2 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/929713:NIASO_RS08050 ^@ http://purl.uniprot.org/uniprot/W0F1B1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/929713:NIASO_RS05005 ^@ http://purl.uniprot.org/uniprot/W0EYZ3 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/929713:NIASO_RS13070 ^@ http://purl.uniprot.org/uniprot/W0EYT8 ^@ Similarity ^@ Belongs to the beta-eliminating lyase family. http://togogenome.org/gene/929713:NIASO_RS17905 ^@ http://purl.uniprot.org/uniprot/W0F4M2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/929713:NIASO_RS07095 ^@ http://purl.uniprot.org/uniprot/W0F142 ^@ Similarity ^@ Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family. http://togogenome.org/gene/929713:NIASO_RS09075 ^@ http://purl.uniprot.org/uniprot/W0F221 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/929713:NIASO_RS00305 ^@ http://purl.uniprot.org/uniprot/W0ETA6 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.|||Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.|||Homodimer.|||Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. http://togogenome.org/gene/929713:NIASO_RS12800 ^@ http://purl.uniprot.org/uniprot/W0EYU5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/929713:NIASO_RS13525 ^@ http://purl.uniprot.org/uniprot/W0F3X2 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/929713:NIASO_RS01450 ^@ http://purl.uniprot.org/uniprot/W0EYH4 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/929713:NIASO_RS03175 ^@ http://purl.uniprot.org/uniprot/W0F2G2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/929713:NIASO_RS17810 ^@ http://purl.uniprot.org/uniprot/W0F5J5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS17735 ^@ http://purl.uniprot.org/uniprot/W0F148 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/929713:NIASO_RS11000 ^@ http://purl.uniprot.org/uniprot/W0F1J7 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/929713:NIASO_RS12645 ^@ http://purl.uniprot.org/uniprot/W0F432 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS07820 ^@ http://purl.uniprot.org/uniprot/W0F175 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/929713:NIASO_RS01810 ^@ http://purl.uniprot.org/uniprot/W0EXL1 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS07805 ^@ http://purl.uniprot.org/uniprot/W0F1I2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/929713:NIASO_RS14320 ^@ http://purl.uniprot.org/uniprot/W0EZG6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/929713:NIASO_RS11980 ^@ http://purl.uniprot.org/uniprot/W0F2V1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS07830 ^@ http://purl.uniprot.org/uniprot/W0F1I5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/929713:NIASO_RS00195 ^@ http://purl.uniprot.org/uniprot/W0EWU4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/929713:NIASO_RS17515 ^@ http://purl.uniprot.org/uniprot/W0F121 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/929713:NIASO_RS14605 ^@ http://purl.uniprot.org/uniprot/W0EZK5 ^@ Function|||Similarity ^@ Belongs to the glycosyl hydrolase 130 family.|||Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose. http://togogenome.org/gene/929713:NIASO_RS10735 ^@ http://purl.uniprot.org/uniprot/W0F2T2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 30 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/929713:NIASO_RS14195 ^@ http://purl.uniprot.org/uniprot/W0F2X3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/929713:NIASO_RS03840 ^@ http://purl.uniprot.org/uniprot/W0EZS1 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/929713:NIASO_RS08850 ^@ http://purl.uniprot.org/uniprot/W0F0J4 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/929713:NIASO_RS13220 ^@ http://purl.uniprot.org/uniprot/W0EZ07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS07615 ^@ http://purl.uniprot.org/uniprot/W0F003 ^@ Similarity ^@ Belongs to the polysaccharide lyase 8 family. http://togogenome.org/gene/929713:NIASO_RS01860 ^@ http://purl.uniprot.org/uniprot/W0EXL8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS18695 ^@ http://purl.uniprot.org/uniprot/W0F1H7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/929713:NIASO_RS11650 ^@ http://purl.uniprot.org/uniprot/W0EYE2 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/929713:NIASO_RS11320 ^@ http://purl.uniprot.org/uniprot/W0EY95 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Belongs to the heat shock protein 70 family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/929713:NIASO_RS14475 ^@ http://purl.uniprot.org/uniprot/W0EZN2 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/929713:NIASO_RS09890 ^@ http://purl.uniprot.org/uniprot/W0F1Z5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/929713:NIASO_RS04565 ^@ http://purl.uniprot.org/uniprot/W0F058 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/929713:NIASO_RS04315 ^@ http://purl.uniprot.org/uniprot/W0EV89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/929713:NIASO_RS08920 ^@ http://purl.uniprot.org/uniprot/W0EWZ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/929713:NIASO_RS16405 ^@ http://purl.uniprot.org/uniprot/W0F0H0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/929713:NIASO_RS14525 ^@ http://purl.uniprot.org/uniprot/W0F435 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS04625 ^@ http://purl.uniprot.org/uniprot/W0EYV0 ^@ Function|||Subunit ^@ Homodimer.|||Represses transcription of the icaADBC operon necessary for biofilm production. http://togogenome.org/gene/929713:NIASO_RS05770 ^@ http://purl.uniprot.org/uniprot/W0EVQ0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.|||In the N-terminal section; belongs to the histidinol-phosphatase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS11375 ^@ http://purl.uniprot.org/uniprot/W0EY51 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/929713:NIASO_RS01585 ^@ http://purl.uniprot.org/uniprot/W0EYV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS02070 ^@ http://purl.uniprot.org/uniprot/W0EYQ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.|||Cytoplasm|||Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.|||Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/929713:NIASO_RS00355 ^@ http://purl.uniprot.org/uniprot/W0EXY8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS02915 ^@ http://purl.uniprot.org/uniprot/W0EUH0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/929713:NIASO_RS09205 ^@ http://purl.uniprot.org/uniprot/W0F1P6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/929713:NIASO_RS09225 ^@ http://purl.uniprot.org/uniprot/W0F0Q2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS02970 ^@ http://purl.uniprot.org/uniprot/W0EZ53 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/929713:NIASO_RS05930 ^@ http://purl.uniprot.org/uniprot/W0EVR0 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/929713:NIASO_RS09720 ^@ http://purl.uniprot.org/uniprot/W0EXC2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/929713:NIASO_RS11670 ^@ http://purl.uniprot.org/uniprot/W0F395 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.|||Cell inner membrane|||Intake of glucose and galactose.|||Membrane http://togogenome.org/gene/929713:NIASO_RS15055 ^@ http://purl.uniprot.org/uniprot/W0F4N6 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/929713:NIASO_RS00395 ^@ http://purl.uniprot.org/uniprot/W0EYA1 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/929713:NIASO_RS12735 ^@ http://purl.uniprot.org/uniprot/W0F362 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/929713:NIASO_RS08485 ^@ http://purl.uniprot.org/uniprot/W0F1F5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS13975 ^@ http://purl.uniprot.org/uniprot/W0EZ81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS17450 ^@ http://purl.uniprot.org/uniprot/W0F869 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/929713:NIASO_RS11105 ^@ http://purl.uniprot.org/uniprot/W0EY23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ribonuclease N1/T1 family.|||Secreted http://togogenome.org/gene/929713:NIASO_RS10260 ^@ http://purl.uniprot.org/uniprot/W0EXS8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/929713:NIASO_RS17835 ^@ http://purl.uniprot.org/uniprot/W0F4L1 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/929713:NIASO_RS16540 ^@ http://purl.uniprot.org/uniprot/W0F4Y4 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/929713:NIASO_RS16320 ^@ http://purl.uniprot.org/uniprot/W0F575 ^@ Function|||Similarity|||Subunit ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.|||Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.|||Homotrimer. http://togogenome.org/gene/929713:NIASO_RS15025 ^@ http://purl.uniprot.org/uniprot/W0F4A3 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS03960 ^@ http://purl.uniprot.org/uniprot/W0EZU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS18190 ^@ http://purl.uniprot.org/uniprot/W0F4R7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/929713:NIASO_RS13920 ^@ http://purl.uniprot.org/uniprot/W0EZ72 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/929713:NIASO_RS04970 ^@ http://purl.uniprot.org/uniprot/W0EVF9 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/929713:NIASO_RS07415 ^@ http://purl.uniprot.org/uniprot/W0F0Z0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/929713:NIASO_RS08205 ^@ http://purl.uniprot.org/uniprot/W0EWR4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 27 family. http://togogenome.org/gene/929713:NIASO_RS01640 ^@ http://purl.uniprot.org/uniprot/W0EU18 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/929713:NIASO_RS15050 ^@ http://purl.uniprot.org/uniprot/W0EZQ9 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/929713:NIASO_RS11985 ^@ http://purl.uniprot.org/uniprot/W0EYD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/929713:NIASO_RS04795 ^@ http://purl.uniprot.org/uniprot/W0EVE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-C family. DnaE2 subfamily.|||Cytoplasm http://togogenome.org/gene/929713:NIASO_RS17120 ^@ http://purl.uniprot.org/uniprot/W0F0T3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/929713:NIASO_RS17455 ^@ http://purl.uniprot.org/uniprot/W0F967 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/929713:NIASO_RS18825 ^@ http://purl.uniprot.org/uniprot/W0F521 ^@ PTM ^@ The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/929713:NIASO_RS05700 ^@ http://purl.uniprot.org/uniprot/W0EVM7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/929713:NIASO_RS02120 ^@ http://purl.uniprot.org/uniprot/W0F5N1 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/929713:NIASO_RS01865 ^@ http://purl.uniprot.org/uniprot/W0F234 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/929713:NIASO_RS09630 ^@ http://purl.uniprot.org/uniprot/W0F2A2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/929713:NIASO_RS07365 ^@ http://purl.uniprot.org/uniprot/W0F190 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/929713:NIASO_RS05085 ^@ http://purl.uniprot.org/uniprot/W0EVF6 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/929713:NIASO_RS18050 ^@ http://purl.uniprot.org/uniprot/W0F193 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.