http://togogenome.org/gene/861561:A325_gp1                                                                                  ^@                                                                                  http://purl.uniprot.org/uniprot/I2E5L7                                                                                  ^@                                                                                  Function|||Similarity|||Subcellular Location Annotation                                                                                  ^@                                                                                  An RNA-dependent RNA polymerase that plays an essential role in the virus replication.|||Belongs to the potyviridae genome polyprotein family.|||Cytoplasmic vesicle|||Has RNA-binding and proteolytic activities.|||Has helicase activity. It may be involved in replication.|||Host cytoplasmic vesicle|||Host nucleus|||Indispensable for virus replication.|||Involved in aphid transmission, cell-to-cell and systemis movement, encapsidation of the viral RNA and in the regulation of viral RNA amplification.|||Nucleus|||Required for aphid transmission and also has proteolytic activity. Only cleaves a Gly-Gly dipeptide at its own C-terminus. Interacts with virions and aphid stylets. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. May have RNA-binding activity.|||Vesicle|||Virion