http://togogenome.org/gene/756499:DESDE_RS12240 ^@ http://purl.uniprot.org/uniprot/I4AA66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0316 family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS07030 ^@ http://purl.uniprot.org/uniprot/I4A7C4 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/756499:DESDE_RS19845 ^@ http://purl.uniprot.org/uniprot/I4AEF7 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/756499:DESDE_RS14895 ^@ http://purl.uniprot.org/uniprot/I4ABN4 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/756499:DESDE_RS01880 ^@ http://purl.uniprot.org/uniprot/I4A4H1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS14840 ^@ http://purl.uniprot.org/uniprot/I4ABM3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/756499:DESDE_RS07090 ^@ http://purl.uniprot.org/uniprot/I4A7D5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS11050 ^@ http://purl.uniprot.org/uniprot/I4A9H9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/756499:DESDE_RS20400 ^@ http://purl.uniprot.org/uniprot/I4AES0 ^@ Similarity ^@ Belongs to the EutP/PduV family. http://togogenome.org/gene/756499:DESDE_RS12275 ^@ http://purl.uniprot.org/uniprot/I4AA73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS01170 ^@ http://purl.uniprot.org/uniprot/I4A433 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS16395 ^@ http://purl.uniprot.org/uniprot/I4ACI4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS13575 ^@ http://purl.uniprot.org/uniprot/I4AAX2 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/756499:DESDE_RS19620 ^@ http://purl.uniprot.org/uniprot/I4AEB3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/756499:DESDE_RS04545 ^@ http://purl.uniprot.org/uniprot/I4A5Y3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/756499:DESDE_RS08960 ^@ http://purl.uniprot.org/uniprot/I4A8E5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/756499:DESDE_RS16805 ^@ http://purl.uniprot.org/uniprot/I4ACR2 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/756499:DESDE_RS19030 ^@ http://purl.uniprot.org/uniprot/I4ADZ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/756499:DESDE_RS03885 ^@ http://purl.uniprot.org/uniprot/I4A5K9 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/756499:DESDE_RS04680 ^@ http://purl.uniprot.org/uniprot/I4A610 ^@ Similarity ^@ Belongs to the SfsA family. http://togogenome.org/gene/756499:DESDE_RS11180 ^@ http://purl.uniprot.org/uniprot/I4A9K6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS00040 ^@ http://purl.uniprot.org/uniprot/I4A3H5 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS06125 ^@ http://purl.uniprot.org/uniprot/I4A6V2 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/756499:DESDE_RS09610 ^@ http://purl.uniprot.org/uniprot/I4A8S3 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/756499:DESDE_RS14765 ^@ http://purl.uniprot.org/uniprot/I4ABL1 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/756499:DESDE_RS18195 ^@ http://purl.uniprot.org/uniprot/I4ADI6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/756499:DESDE_RS01575 ^@ http://purl.uniprot.org/uniprot/I4A4B0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS16420 ^@ http://purl.uniprot.org/uniprot/I4ACI9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/756499:DESDE_RS05555 ^@ http://purl.uniprot.org/uniprot/I4A6I6 ^@ Similarity ^@ Belongs to the hyi family. http://togogenome.org/gene/756499:DESDE_RS05770 ^@ http://purl.uniprot.org/uniprot/I4A6N0 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/756499:DESDE_RS19365 ^@ http://purl.uniprot.org/uniprot/I4AE63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS16585 ^@ http://purl.uniprot.org/uniprot/I4ACL7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/756499:DESDE_RS14680 ^@ http://purl.uniprot.org/uniprot/I4ABJ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/756499:DESDE_RS13360 ^@ http://purl.uniprot.org/uniprot/I4AAT1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/756499:DESDE_RS20695 ^@ http://purl.uniprot.org/uniprot/I4AEX7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/756499:DESDE_RS10830 ^@ http://purl.uniprot.org/uniprot/I4A9D6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/756499:DESDE_RS02420 ^@ http://purl.uniprot.org/uniprot/I4A4S0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS03065 ^@ http://purl.uniprot.org/uniprot/I4A545 ^@ Cofactor|||Similarity ^@ Belongs to the arginase family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/756499:DESDE_RS05635 ^@ http://purl.uniprot.org/uniprot/I4A6K1 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/756499:DESDE_RS20305 ^@ http://purl.uniprot.org/uniprot/I4AEQ1 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/756499:DESDE_RS09645 ^@ http://purl.uniprot.org/uniprot/I4A8T0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/756499:DESDE_RS03555 ^@ http://purl.uniprot.org/uniprot/I4A5E2 ^@ Similarity ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family. http://togogenome.org/gene/756499:DESDE_RS20155 ^@ http://purl.uniprot.org/uniprot/I4AEL9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/756499:DESDE_RS09615 ^@ http://purl.uniprot.org/uniprot/I4A8S4 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/756499:DESDE_RS08995 ^@ http://purl.uniprot.org/uniprot/I4A8F2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS00960 ^@ http://purl.uniprot.org/uniprot/I4A3Z3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/756499:DESDE_RS18140 ^@ http://purl.uniprot.org/uniprot/I4ADH5 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/756499:DESDE_RS13635 ^@ http://purl.uniprot.org/uniprot/I4AAY4 ^@ Similarity|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.|||Heterodimer of a large and a small subunit. http://togogenome.org/gene/756499:DESDE_RS13840 ^@ http://purl.uniprot.org/uniprot/I4AB24 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS09705 ^@ http://purl.uniprot.org/uniprot/I4A8U4 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/756499:DESDE_RS12515 ^@ http://purl.uniprot.org/uniprot/I4AAC4 ^@ Function|||Similarity ^@ Belongs to the CinA family.|||May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/756499:DESDE_RS13510 ^@ http://purl.uniprot.org/uniprot/I4AAV9 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/756499:DESDE_RS01175 ^@ http://purl.uniprot.org/uniprot/I4A434 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/756499:DESDE_RS11250 ^@ http://purl.uniprot.org/uniprot/I4A9M1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS17525 ^@ http://purl.uniprot.org/uniprot/I4AD53 ^@ Cofactor|||PTM|||Similarity ^@ Belongs to the NapC/NirT/NrfH family.|||Binds 4 heme groups per subunit. http://togogenome.org/gene/756499:DESDE_RS17970 ^@ http://purl.uniprot.org/uniprot/I4ADE1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/756499:DESDE_RS17095 ^@ http://purl.uniprot.org/uniprot/I4ACX1 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS09355 ^@ http://purl.uniprot.org/uniprot/I4A8M0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS20165 ^@ http://purl.uniprot.org/uniprot/I4AEM1 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/756499:DESDE_RS02145 ^@ http://purl.uniprot.org/uniprot/I4A4M1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/756499:DESDE_RS02665 ^@ http://purl.uniprot.org/uniprot/I4A4W9 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/756499:DESDE_RS02655 ^@ http://purl.uniprot.org/uniprot/I4A4W7 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/756499:DESDE_RS15080 ^@ http://purl.uniprot.org/uniprot/I4ABR9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS08415 ^@ http://purl.uniprot.org/uniprot/I4A839 ^@ Similarity ^@ Belongs to the CbxX/CfxQ family. http://togogenome.org/gene/756499:DESDE_RS07935 ^@ http://purl.uniprot.org/uniprot/I4A7U7 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/756499:DESDE_RS15315 ^@ http://purl.uniprot.org/uniprot/I4ABW7 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/756499:DESDE_RS06680 ^@ http://purl.uniprot.org/uniprot/I4A760 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS20350 ^@ http://purl.uniprot.org/uniprot/I4AER0 ^@ Function|||Similarity ^@ Belongs to the PduL family.|||Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. http://togogenome.org/gene/756499:DESDE_RS15075 ^@ http://purl.uniprot.org/uniprot/I4ABR8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CodY family.|||Cytoplasm|||DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor. http://togogenome.org/gene/756499:DESDE_RS02560 ^@ http://purl.uniprot.org/uniprot/I4A4U8 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/756499:DESDE_RS18090 ^@ http://purl.uniprot.org/uniprot/I4ADG5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/756499:DESDE_RS00800 ^@ http://purl.uniprot.org/uniprot/I4A3W1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer. http://togogenome.org/gene/756499:DESDE_RS13020 ^@ http://purl.uniprot.org/uniprot/I4AAL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LTA synthase family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS14755 ^@ http://purl.uniprot.org/uniprot/I4ABK9 ^@ Similarity ^@ Belongs to the cytochrome c-552 family. http://togogenome.org/gene/756499:DESDE_RS06690 ^@ http://purl.uniprot.org/uniprot/I4A762 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/756499:DESDE_RS02150 ^@ http://purl.uniprot.org/uniprot/I4A4M2 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/756499:DESDE_RS06290 ^@ http://purl.uniprot.org/uniprot/I4A6Y4 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS01390 ^@ http://purl.uniprot.org/uniprot/I4A473 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS06950 ^@ http://purl.uniprot.org/uniprot/I4A7B2 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/756499:DESDE_RS16455 ^@ http://purl.uniprot.org/uniprot/I4ACJ6 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/756499:DESDE_RS02020 ^@ http://purl.uniprot.org/uniprot/I4A4J6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/756499:DESDE_RS03240 ^@ http://purl.uniprot.org/uniprot/I4A579 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/756499:DESDE_RS05620 ^@ http://purl.uniprot.org/uniprot/I4A6J8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrcB (TC 9.B.71) family.|||Cell membrane|||Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane http://togogenome.org/gene/756499:DESDE_RS08075 ^@ http://purl.uniprot.org/uniprot/I4A7X5 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/756499:DESDE_RS08490 ^@ http://purl.uniprot.org/uniprot/I4A851 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/756499:DESDE_RS01820 ^@ http://purl.uniprot.org/uniprot/I4A4F9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS11505 ^@ http://purl.uniprot.org/uniprot/I4A9R6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/756499:DESDE_RS13685 ^@ http://purl.uniprot.org/uniprot/I4AAZ2 ^@ Similarity ^@ Belongs to the UPF0735 family. http://togogenome.org/gene/756499:DESDE_RS05605 ^@ http://purl.uniprot.org/uniprot/I4A6J5 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/756499:DESDE_RS06825 ^@ http://purl.uniprot.org/uniprot/I4A787 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/756499:DESDE_RS14815 ^@ http://purl.uniprot.org/uniprot/I4ABM1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS20295 ^@ http://purl.uniprot.org/uniprot/I4AEP8 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/756499:DESDE_RS20230 ^@ http://purl.uniprot.org/uniprot/I4AEN4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/756499:DESDE_RS12885 ^@ http://purl.uniprot.org/uniprot/I4AAI5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/756499:DESDE_RS02710 ^@ http://purl.uniprot.org/uniprot/I4A4X9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS10615 ^@ http://purl.uniprot.org/uniprot/I4A990 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/756499:DESDE_RS15100 ^@ http://purl.uniprot.org/uniprot/I4ABS3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/756499:DESDE_RS01025 ^@ http://purl.uniprot.org/uniprot/I4A406 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS16755 ^@ http://purl.uniprot.org/uniprot/I4ACQ2 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS02140 ^@ http://purl.uniprot.org/uniprot/I4A4M0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/756499:DESDE_RS10725 ^@ http://purl.uniprot.org/uniprot/I4A9B3 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/756499:DESDE_RS15645 ^@ http://purl.uniprot.org/uniprot/I4AC33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.|||Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS11980 ^@ http://purl.uniprot.org/uniprot/I4AA15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS17055 ^@ http://purl.uniprot.org/uniprot/I4ACW3 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS14005 ^@ http://purl.uniprot.org/uniprot/I4AB57 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/756499:DESDE_RS12055 ^@ http://purl.uniprot.org/uniprot/I4AA29 ^@ Caution|||Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/756499:DESDE_RS11545 ^@ http://purl.uniprot.org/uniprot/I4A9S4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS06935 ^@ http://purl.uniprot.org/uniprot/I4A7A9 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/756499:DESDE_RS17290 ^@ http://purl.uniprot.org/uniprot/I4AD09 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/756499:DESDE_RS12435 ^@ http://purl.uniprot.org/uniprot/I4AAA8 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/756499:DESDE_RS09455 ^@ http://purl.uniprot.org/uniprot/I4A8P3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/756499:DESDE_RS01690 ^@ http://purl.uniprot.org/uniprot/I4A4D2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS10275 ^@ http://purl.uniprot.org/uniprot/I4A928 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiN family.|||Cell membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/756499:DESDE_RS08945 ^@ http://purl.uniprot.org/uniprot/I4A8E2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/756499:DESDE_RS03340 ^@ http://purl.uniprot.org/uniprot/I4A597 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/756499:DESDE_RS14910 ^@ http://purl.uniprot.org/uniprot/I4ABN7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/756499:DESDE_RS01780 ^@ http://purl.uniprot.org/uniprot/I4A4F1 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS11110 ^@ http://purl.uniprot.org/uniprot/I4A9J3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS14775 ^@ http://purl.uniprot.org/uniprot/I4ABL3 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/756499:DESDE_RS07485 ^@ http://purl.uniprot.org/uniprot/I4A7K9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS03960 ^@ http://purl.uniprot.org/uniprot/I4A5M2 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/756499:DESDE_RS09340 ^@ http://purl.uniprot.org/uniprot/I4A8L8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS20415 ^@ http://purl.uniprot.org/uniprot/I4AES2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the organic radical-activating enzymes family.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM). http://togogenome.org/gene/756499:DESDE_RS09875 ^@ http://purl.uniprot.org/uniprot/I4A8X6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS15620 ^@ http://purl.uniprot.org/uniprot/I4AC28 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/756499:DESDE_RS09975 ^@ http://purl.uniprot.org/uniprot/I4A8Z6 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/756499:DESDE_RS03245 ^@ http://purl.uniprot.org/uniprot/I4A580 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS17885 ^@ http://purl.uniprot.org/uniprot/I4ADC4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS13370 ^@ http://purl.uniprot.org/uniprot/I4AAT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS03295 ^@ http://purl.uniprot.org/uniprot/I4A589 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/756499:DESDE_RS20125 ^@ http://purl.uniprot.org/uniprot/I4AEL3 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/756499:DESDE_RS13695 ^@ http://purl.uniprot.org/uniprot/I4AAZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS05945 ^@ http://purl.uniprot.org/uniprot/I4A6R6 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.|||Catalytic subunit of the nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.|||Component of the nitrate reductase NapAB complex composed of NapA and NapB.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.|||Secreted http://togogenome.org/gene/756499:DESDE_RS15400 ^@ http://purl.uniprot.org/uniprot/I4ABY5 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/756499:DESDE_RS03330 ^@ http://purl.uniprot.org/uniprot/I4A595 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS12860 ^@ http://purl.uniprot.org/uniprot/I4AAI0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell membrane|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/756499:DESDE_RS14540 ^@ http://purl.uniprot.org/uniprot/I4ABG4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS00955 ^@ http://purl.uniprot.org/uniprot/I4A3Z2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/756499:DESDE_RS13040 ^@ http://purl.uniprot.org/uniprot/I4AAL5 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/756499:DESDE_RS10045 ^@ http://purl.uniprot.org/uniprot/I4A910 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS06910 ^@ http://purl.uniprot.org/uniprot/I4A7A4 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/756499:DESDE_RS18335 ^@ http://purl.uniprot.org/uniprot/I4ADL0 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/756499:DESDE_RS14695 ^@ http://purl.uniprot.org/uniprot/I4ABJ7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/756499:DESDE_RS03485 ^@ http://purl.uniprot.org/uniprot/I4A5C8 ^@ Similarity ^@ Belongs to the GerABKA family. http://togogenome.org/gene/756499:DESDE_RS10515 ^@ http://purl.uniprot.org/uniprot/I4A970 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS01770 ^@ http://purl.uniprot.org/uniprot/I4A4E9 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/756499:DESDE_RS18250 ^@ http://purl.uniprot.org/uniprot/I4ADJ6 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters.|||Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. http://togogenome.org/gene/756499:DESDE_RS09000 ^@ http://purl.uniprot.org/uniprot/I4A8F3 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/756499:DESDE_RS01055 ^@ http://purl.uniprot.org/uniprot/I4A412 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS15630 ^@ http://purl.uniprot.org/uniprot/I4AC30 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS06810 ^@ http://purl.uniprot.org/uniprot/I4A784 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS02880 ^@ http://purl.uniprot.org/uniprot/I4A507 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/756499:DESDE_RS01865 ^@ http://purl.uniprot.org/uniprot/I4A4G8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS18345 ^@ http://purl.uniprot.org/uniprot/I4ADL2 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/756499:DESDE_RS16465 ^@ http://purl.uniprot.org/uniprot/I4ACJ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MenA family. Type 1 subfamily.|||Cell membrane|||Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).|||Membrane http://togogenome.org/gene/756499:DESDE_RS05640 ^@ http://purl.uniprot.org/uniprot/I4A6K2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS08735 ^@ http://purl.uniprot.org/uniprot/I4A8A0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS02015 ^@ http://purl.uniprot.org/uniprot/I4A4J5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/756499:DESDE_RS00235 ^@ http://purl.uniprot.org/uniprot/I4A3L0 ^@ Similarity ^@ Belongs to the GerABKC lipoprotein family. http://togogenome.org/gene/756499:DESDE_RS07480 ^@ http://purl.uniprot.org/uniprot/I4A7K8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS08625 ^@ http://purl.uniprot.org/uniprot/I4A878 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/756499:DESDE_RS14720 ^@ http://purl.uniprot.org/uniprot/I4ABK2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/756499:DESDE_RS20575 ^@ http://purl.uniprot.org/uniprot/I4AEV2 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/756499:DESDE_RS19140 ^@ http://purl.uniprot.org/uniprot/I4AE19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS01470 ^@ http://purl.uniprot.org/uniprot/I4A489 ^@ Function ^@ Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. http://togogenome.org/gene/756499:DESDE_RS19745 ^@ http://purl.uniprot.org/uniprot/I4AED5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/756499:DESDE_RS11160 ^@ http://purl.uniprot.org/uniprot/I4A9K2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase D family. Cardiolipin synthase subfamily.|||Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/756499:DESDE_RS03875 ^@ http://purl.uniprot.org/uniprot/I4A5K7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 3 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS10835 ^@ http://purl.uniprot.org/uniprot/I4A9D7 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/756499:DESDE_RS13110 ^@ http://purl.uniprot.org/uniprot/I4AAN0 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/756499:DESDE_RS03520 ^@ http://purl.uniprot.org/uniprot/I4A5D5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DsrC/TusE family.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS15635 ^@ http://purl.uniprot.org/uniprot/I4AC31 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/756499:DESDE_RS02305 ^@ http://purl.uniprot.org/uniprot/I4A4Q1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS06310 ^@ http://purl.uniprot.org/uniprot/I4A6Y8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS13770 ^@ http://purl.uniprot.org/uniprot/I4AB09 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS02480 ^@ http://purl.uniprot.org/uniprot/I4A4T2 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/756499:DESDE_RS04780 ^@ http://purl.uniprot.org/uniprot/I4A629 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS16385 ^@ http://purl.uniprot.org/uniprot/I4ACI2 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/756499:DESDE_RS03740 ^@ http://purl.uniprot.org/uniprot/I4A5I0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/756499:DESDE_RS02425 ^@ http://purl.uniprot.org/uniprot/I4A4S1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS05735 ^@ http://purl.uniprot.org/uniprot/I4A6M3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/756499:DESDE_RS10645 ^@ http://purl.uniprot.org/uniprot/I4A996 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS02200 ^@ http://purl.uniprot.org/uniprot/I4A4N1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/756499:DESDE_RS00615 ^@ http://purl.uniprot.org/uniprot/I4A3T4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS17245 ^@ http://purl.uniprot.org/uniprot/I4AD00 ^@ Similarity ^@ Belongs to the FlgM family. http://togogenome.org/gene/756499:DESDE_RS13815 ^@ http://purl.uniprot.org/uniprot/I4AB18 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell membrane|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/756499:DESDE_RS12225 ^@ http://purl.uniprot.org/uniprot/I4AA64 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M3B family.|||Binds 1 zinc ion.|||Has oligopeptidase activity and degrades a variety of small bioactive peptides. http://togogenome.org/gene/756499:DESDE_RS18560 ^@ http://purl.uniprot.org/uniprot/I4ADQ5 ^@ Similarity ^@ In the C-terminal section; belongs to the anthranilate synthase component I family. http://togogenome.org/gene/756499:DESDE_RS00030 ^@ http://purl.uniprot.org/uniprot/I4A3H3 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/756499:DESDE_RS14185 ^@ http://purl.uniprot.org/uniprot/I4AB95 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS16680 ^@ http://purl.uniprot.org/uniprot/I4ACN7 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS18890 ^@ http://purl.uniprot.org/uniprot/I4ADW9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS19125 ^@ http://purl.uniprot.org/uniprot/I4AE16 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/756499:DESDE_RS18940 ^@ http://purl.uniprot.org/uniprot/I4ADX9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HCP family.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 hybrid [4Fe-2O-2S] cluster.|||Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS10735 ^@ http://purl.uniprot.org/uniprot/I4A9B5 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/756499:DESDE_RS09640 ^@ http://purl.uniprot.org/uniprot/I4A8S9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/756499:DESDE_RS01335 ^@ http://purl.uniprot.org/uniprot/I4A462 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DsrC/TusE family.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS03975 ^@ http://purl.uniprot.org/uniprot/I4A5M5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS16225 ^@ http://purl.uniprot.org/uniprot/I4ACE9 ^@ Similarity ^@ Belongs to the RemA family. http://togogenome.org/gene/756499:DESDE_RS06830 ^@ http://purl.uniprot.org/uniprot/I4A788 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the PRA-PH family.|||In the N-terminal section; belongs to the PRA-CH family. http://togogenome.org/gene/756499:DESDE_RS09965 ^@ http://purl.uniprot.org/uniprot/I4A8Z4 ^@ Function ^@ Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. http://togogenome.org/gene/756499:DESDE_RS18120 ^@ http://purl.uniprot.org/uniprot/I4ADH1 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/756499:DESDE_RS17935 ^@ http://purl.uniprot.org/uniprot/I4ADD4 ^@ Similarity ^@ Belongs to the MtrH family. http://togogenome.org/gene/756499:DESDE_RS06945 ^@ http://purl.uniprot.org/uniprot/I4A7B1 ^@ Function|||Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family.|||This protein is a Fe-Mo-cofactor biosynthetic component. http://togogenome.org/gene/756499:DESDE_RS10060 ^@ http://purl.uniprot.org/uniprot/I4A913 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS13895 ^@ http://purl.uniprot.org/uniprot/I4AB35 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/756499:DESDE_RS04350 ^@ http://purl.uniprot.org/uniprot/I4A5U4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS06670 ^@ http://purl.uniprot.org/uniprot/I4A758 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/756499:DESDE_RS14990 ^@ http://purl.uniprot.org/uniprot/I4ABQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS08125 ^@ http://purl.uniprot.org/uniprot/I4A7Y5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS19890 ^@ http://purl.uniprot.org/uniprot/I4AEG6 ^@ Caution|||Function|||Similarity ^@ Belongs to the type IA topoisomerase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/756499:DESDE_RS14870 ^@ http://purl.uniprot.org/uniprot/I4ABM9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/756499:DESDE_RS20670 ^@ http://purl.uniprot.org/uniprot/I4AEX1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/756499:DESDE_RS09405 ^@ http://purl.uniprot.org/uniprot/I4A8N1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/756499:DESDE_RS18015 ^@ http://purl.uniprot.org/uniprot/I4ADF0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/756499:DESDE_RS00640 ^@ http://purl.uniprot.org/uniprot/I4A3T9 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/756499:DESDE_RS19205 ^@ http://purl.uniprot.org/uniprot/I4AE32 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/756499:DESDE_RS20360 ^@ http://purl.uniprot.org/uniprot/I4AER2 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/756499:DESDE_RS15615 ^@ http://purl.uniprot.org/uniprot/I4AC27 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/756499:DESDE_RS05930 ^@ http://purl.uniprot.org/uniprot/I4A6R3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/756499:DESDE_RS08655 ^@ http://purl.uniprot.org/uniprot/I4A884 ^@ Function|||Similarity ^@ Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/756499:DESDE_RS15870 ^@ http://purl.uniprot.org/uniprot/I4AC77 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS03940 ^@ http://purl.uniprot.org/uniprot/I4A5L8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS13890 ^@ http://purl.uniprot.org/uniprot/I4AB34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS09905 ^@ http://purl.uniprot.org/uniprot/I4A8Y2 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/756499:DESDE_RS17880 ^@ http://purl.uniprot.org/uniprot/I4ADC3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS06835 ^@ http://purl.uniprot.org/uniprot/I4A789 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ApbE family.|||Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.|||Magnesium. Can also use manganese. http://togogenome.org/gene/756499:DESDE_RS18735 ^@ http://purl.uniprot.org/uniprot/I4ADT7 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/756499:DESDE_RS13960 ^@ http://purl.uniprot.org/uniprot/I4AB48 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/756499:DESDE_RS08405 ^@ http://purl.uniprot.org/uniprot/I4A837 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/756499:DESDE_RS11880 ^@ http://purl.uniprot.org/uniprot/I4A9Z4 ^@ Function|||Similarity ^@ Belongs to the alpha/beta-type SASP family.|||SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. http://togogenome.org/gene/756499:DESDE_RS07060 ^@ http://purl.uniprot.org/uniprot/I4A7D0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS06065 ^@ http://purl.uniprot.org/uniprot/I4A6T9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS14730 ^@ http://purl.uniprot.org/uniprot/I4ABK4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/756499:DESDE_RS20680 ^@ http://purl.uniprot.org/uniprot/I4AEX3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS03985 ^@ http://purl.uniprot.org/uniprot/I4A5M7 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/756499:DESDE_RS19570 ^@ http://purl.uniprot.org/uniprot/I4AEA4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/756499:DESDE_RS16390 ^@ http://purl.uniprot.org/uniprot/I4ACI3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS05585 ^@ http://purl.uniprot.org/uniprot/I4A6J1 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/756499:DESDE_RS17060 ^@ http://purl.uniprot.org/uniprot/I4ACW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliN/MopA/SpaO family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS07945 ^@ http://purl.uniprot.org/uniprot/I4A7U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS19260 ^@ http://purl.uniprot.org/uniprot/I4AE43 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS16705 ^@ http://purl.uniprot.org/uniprot/I4ACP2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sbp family.|||Cell membrane http://togogenome.org/gene/756499:DESDE_RS01900 ^@ http://purl.uniprot.org/uniprot/I4A4H5 ^@ Activity Regulation|||Function|||Similarity ^@ Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.|||Belongs to the ATP:guanido phosphotransferase family.|||Catalyzes the specific phosphorylation of arginine residues in proteins. http://togogenome.org/gene/756499:DESDE_RS20245 ^@ http://purl.uniprot.org/uniprot/I4AEN8 ^@ Similarity ^@ Belongs to the SleB family. http://togogenome.org/gene/756499:DESDE_RS03835 ^@ http://purl.uniprot.org/uniprot/I4A5J9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS10760 ^@ http://purl.uniprot.org/uniprot/I4A9C0 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/756499:DESDE_RS16700 ^@ http://purl.uniprot.org/uniprot/I4ACP1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/756499:DESDE_RS13645 ^@ http://purl.uniprot.org/uniprot/I4AAY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HupC/HyaC/HydC family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS03445 ^@ http://purl.uniprot.org/uniprot/I4A5B9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS16915 ^@ http://purl.uniprot.org/uniprot/I4ACT5 ^@ Similarity ^@ Belongs to the PAPS reductase family. CysD subfamily. http://togogenome.org/gene/756499:DESDE_RS07285 ^@ http://purl.uniprot.org/uniprot/I4A7H3 ^@ Similarity ^@ Belongs to the pyruvoyl-dependent arginine decarboxylase family. http://togogenome.org/gene/756499:DESDE_RS01875 ^@ http://purl.uniprot.org/uniprot/I4A4H0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS16275 ^@ http://purl.uniprot.org/uniprot/I4ACF8 ^@ Function|||Similarity|||Subunit ^@ Associates with stalled 50S ribosomal subunits.|||Belongs to the NEMF family.|||Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. http://togogenome.org/gene/756499:DESDE_RS18295 ^@ http://purl.uniprot.org/uniprot/I4ADK2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.|||Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS03010 ^@ http://purl.uniprot.org/uniprot/I4A534 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/756499:DESDE_RS16290 ^@ http://purl.uniprot.org/uniprot/I4ACG2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS12495 ^@ http://purl.uniprot.org/uniprot/I4AAC0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS10590 ^@ http://purl.uniprot.org/uniprot/I4A985 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS03040 ^@ http://purl.uniprot.org/uniprot/I4A540 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. http://togogenome.org/gene/756499:DESDE_RS15685 ^@ http://purl.uniprot.org/uniprot/I4AC41 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/756499:DESDE_RS11165 ^@ http://purl.uniprot.org/uniprot/I4A9K3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS18690 ^@ http://purl.uniprot.org/uniprot/I4ADS9 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/756499:DESDE_RS06270 ^@ http://purl.uniprot.org/uniprot/I4A6Y1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS01930 ^@ http://purl.uniprot.org/uniprot/I4A4I1 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/756499:DESDE_RS13930 ^@ http://purl.uniprot.org/uniprot/I4AB42 ^@ Similarity ^@ Belongs to the GerABKA family. http://togogenome.org/gene/756499:DESDE_RS09095 ^@ http://purl.uniprot.org/uniprot/I4A8H0 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/756499:DESDE_RS20220 ^@ http://purl.uniprot.org/uniprot/I4AEN2 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS03670 ^@ http://purl.uniprot.org/uniprot/I4A5G5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/756499:DESDE_RS05700 ^@ http://purl.uniprot.org/uniprot/I4A6L6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/756499:DESDE_RS15035 ^@ http://purl.uniprot.org/uniprot/I4ABR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS19860 ^@ http://purl.uniprot.org/uniprot/I4AEG0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS18100 ^@ http://purl.uniprot.org/uniprot/I4ADG7 ^@ Similarity ^@ Belongs to the class-II fumarase/aspartase family. Aspartase subfamily. http://togogenome.org/gene/756499:DESDE_RS08750 ^@ http://purl.uniprot.org/uniprot/I4A8A3 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/756499:DESDE_RS03110 ^@ http://purl.uniprot.org/uniprot/I4A553 ^@ Similarity ^@ Belongs to the ThrE exporter (TC 2.A.79) family. http://togogenome.org/gene/756499:DESDE_RS09710 ^@ http://purl.uniprot.org/uniprot/I4A8U5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS16750 ^@ http://purl.uniprot.org/uniprot/I4ACQ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/756499:DESDE_RS02165 ^@ http://purl.uniprot.org/uniprot/I4A4M5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/756499:DESDE_RS17565 ^@ http://purl.uniprot.org/uniprot/I4AD61 ^@ Similarity ^@ Belongs to the UPF0751 family. http://togogenome.org/gene/756499:DESDE_RS14100 ^@ http://purl.uniprot.org/uniprot/I4AB78 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/756499:DESDE_RS04475 ^@ http://purl.uniprot.org/uniprot/I4A5W9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/756499:DESDE_RS05965 ^@ http://purl.uniprot.org/uniprot/I4A6S0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/756499:DESDE_RS09540 ^@ http://purl.uniprot.org/uniprot/I4A8Q9 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/756499:DESDE_RS02055 ^@ http://purl.uniprot.org/uniprot/I4A4K3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/756499:DESDE_RS03590 ^@ http://purl.uniprot.org/uniprot/I4A5E9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS10675 ^@ http://purl.uniprot.org/uniprot/I4A9A2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/756499:DESDE_RS14850 ^@ http://purl.uniprot.org/uniprot/I4ABM5 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine. http://togogenome.org/gene/756499:DESDE_RS14265 ^@ http://purl.uniprot.org/uniprot/I4ABA8 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/756499:DESDE_RS02635 ^@ http://purl.uniprot.org/uniprot/I4A4W3 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/756499:DESDE_RS15970 ^@ http://purl.uniprot.org/uniprot/I4AC97 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/756499:DESDE_RS08025 ^@ http://purl.uniprot.org/uniprot/I4A7W5 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. http://togogenome.org/gene/756499:DESDE_RS04595 ^@ http://purl.uniprot.org/uniprot/I4A5Z3 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/756499:DESDE_RS00700 ^@ http://purl.uniprot.org/uniprot/I4A3U5 ^@ Similarity ^@ Belongs to the DltD family. http://togogenome.org/gene/756499:DESDE_RS08055 ^@ http://purl.uniprot.org/uniprot/I4A7X1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS05580 ^@ http://purl.uniprot.org/uniprot/I4A6J0 ^@ Subunit ^@ Homotetramer. http://togogenome.org/gene/756499:DESDE_RS20630 ^@ http://purl.uniprot.org/uniprot/I4AEW3 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/756499:DESDE_RS12120 ^@ http://purl.uniprot.org/uniprot/I4AA42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS07010 ^@ http://purl.uniprot.org/uniprot/I4A7C0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS06715 ^@ http://purl.uniprot.org/uniprot/I4A767 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS02700 ^@ http://purl.uniprot.org/uniprot/I4A4X7 ^@ Similarity ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family. http://togogenome.org/gene/756499:DESDE_RS05755 ^@ http://purl.uniprot.org/uniprot/I4A6M7 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/756499:DESDE_RS17035 ^@ http://purl.uniprot.org/uniprot/U3GJM4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/756499:DESDE_RS18950 ^@ http://purl.uniprot.org/uniprot/I4ADY1 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS16025 ^@ http://purl.uniprot.org/uniprot/I4ACA8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS12090 ^@ http://purl.uniprot.org/uniprot/I4AA36 ^@ Cofactor|||Function|||Subcellular Location Annotation ^@ Binds 1 Ca(2+) ion per subunit.|||Cytoplasm|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS05660 ^@ http://purl.uniprot.org/uniprot/I4A6K6 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/756499:DESDE_RS06635 ^@ http://purl.uniprot.org/uniprot/I4A751 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS20140 ^@ http://purl.uniprot.org/uniprot/I4AEL6 ^@ Similarity ^@ Belongs to the UPF0340 family. http://togogenome.org/gene/756499:DESDE_RS01460 ^@ http://purl.uniprot.org/uniprot/I4A487 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS14325 ^@ http://purl.uniprot.org/uniprot/I4ABC0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/756499:DESDE_RS18770 ^@ http://purl.uniprot.org/uniprot/I4ADU4 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/756499:DESDE_RS17780 ^@ http://purl.uniprot.org/uniprot/I4ADA3 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/756499:DESDE_RS00465 ^@ http://purl.uniprot.org/uniprot/I4A3Q5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/756499:DESDE_RS16715 ^@ http://purl.uniprot.org/uniprot/I4ACP4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS08790 ^@ http://purl.uniprot.org/uniprot/I4A8B1 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/756499:DESDE_RS20660 ^@ http://purl.uniprot.org/uniprot/I4AEW9 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/756499:DESDE_RS00685 ^@ http://purl.uniprot.org/uniprot/I4A3U2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.|||Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS01330 ^@ http://purl.uniprot.org/uniprot/I4A461 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS17145 ^@ http://purl.uniprot.org/uniprot/I4ACY1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/756499:DESDE_RS12935 ^@ http://purl.uniprot.org/uniprot/I4AAJ5 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/756499:DESDE_RS14145 ^@ http://purl.uniprot.org/uniprot/I4AB87 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS01510 ^@ http://purl.uniprot.org/uniprot/I4A497 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/756499:DESDE_RS15235 ^@ http://purl.uniprot.org/uniprot/I4ABV1 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/756499:DESDE_RS01910 ^@ http://purl.uniprot.org/uniprot/I4A4H7 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/756499:DESDE_RS11735 ^@ http://purl.uniprot.org/uniprot/I4A9W3 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/756499:DESDE_RS00505 ^@ http://purl.uniprot.org/uniprot/I4A3R3 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/756499:DESDE_RS06040 ^@ http://purl.uniprot.org/uniprot/I4A6T3 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/756499:DESDE_RS20555 ^@ http://purl.uniprot.org/uniprot/I4AEU8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/756499:DESDE_RS01110 ^@ http://purl.uniprot.org/uniprot/I4A420 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS01725 ^@ http://purl.uniprot.org/uniprot/I4A4E0 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/756499:DESDE_RS20145 ^@ http://purl.uniprot.org/uniprot/I4AEL7 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/756499:DESDE_RS05045 ^@ http://purl.uniprot.org/uniprot/I4A682 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/756499:DESDE_RS11520 ^@ http://purl.uniprot.org/uniprot/I4A9R9 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS17350 ^@ http://purl.uniprot.org/uniprot/I4AD19 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/756499:DESDE_RS17420 ^@ http://purl.uniprot.org/uniprot/I4AD32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS14745 ^@ http://purl.uniprot.org/uniprot/I4ABK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS16735 ^@ http://purl.uniprot.org/uniprot/I4ACP8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS04805 ^@ http://purl.uniprot.org/uniprot/I4A634 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/756499:DESDE_RS18060 ^@ http://purl.uniprot.org/uniprot/I4ADF9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/756499:DESDE_RS14685 ^@ http://purl.uniprot.org/uniprot/I4ABJ5 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/756499:DESDE_RS05570 ^@ http://purl.uniprot.org/uniprot/I4A6I8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS00945 ^@ http://purl.uniprot.org/uniprot/I4A3Z0 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/756499:DESDE_RS19815 ^@ http://purl.uniprot.org/uniprot/I4AEF0 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.|||Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid. http://togogenome.org/gene/756499:DESDE_RS04685 ^@ http://purl.uniprot.org/uniprot/I4A611 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/756499:DESDE_RS18065 ^@ http://purl.uniprot.org/uniprot/I4ADG0 ^@ Similarity ^@ Belongs to the transpeptidase family. http://togogenome.org/gene/756499:DESDE_RS14690 ^@ http://purl.uniprot.org/uniprot/I4ABJ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/756499:DESDE_RS01220 ^@ http://purl.uniprot.org/uniprot/I4A438 ^@ Similarity ^@ Belongs to the GerABKC lipoprotein family. http://togogenome.org/gene/756499:DESDE_RS19585 ^@ http://purl.uniprot.org/uniprot/I4AEA7 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/756499:DESDE_RS14565 ^@ http://purl.uniprot.org/uniprot/I4ABG9 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/756499:DESDE_RS15015 ^@ http://purl.uniprot.org/uniprot/I4ABQ6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS11440 ^@ http://purl.uniprot.org/uniprot/I4A9Q3 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/756499:DESDE_RS12755 ^@ http://purl.uniprot.org/uniprot/I4AAG5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS19810 ^@ http://purl.uniprot.org/uniprot/I4AEE9 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. SigI subfamily.|||Cytoplasm|||Interacts with RsgI.|||Negatively regulated by the anti-sigma-I factor RsgI.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/756499:DESDE_RS17775 ^@ http://purl.uniprot.org/uniprot/I4ADA2 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/756499:DESDE_RS01140 ^@ http://purl.uniprot.org/uniprot/I4A426 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/756499:DESDE_RS16780 ^@ http://purl.uniprot.org/uniprot/I4ACQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS12700 ^@ http://purl.uniprot.org/uniprot/I4AAG0 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/756499:DESDE_RS15705 ^@ http://purl.uniprot.org/uniprot/I4AC45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS18180 ^@ http://purl.uniprot.org/uniprot/I4ADI3 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/756499:DESDE_RS10690 ^@ http://purl.uniprot.org/uniprot/I4A9A5 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/756499:DESDE_RS14885 ^@ http://purl.uniprot.org/uniprot/I4ABN2 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/756499:DESDE_RS14650 ^@ http://purl.uniprot.org/uniprot/I4ABI6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS12745 ^@ http://purl.uniprot.org/uniprot/I4AAG3 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS07565 ^@ http://purl.uniprot.org/uniprot/I4A7M4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS12645 ^@ http://purl.uniprot.org/uniprot/I4AAF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS20020 ^@ http://purl.uniprot.org/uniprot/I4AEJ2 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/756499:DESDE_RS01580 ^@ http://purl.uniprot.org/uniprot/I4A4B1 ^@ Subcellular Location Annotation ^@ Periplasm http://togogenome.org/gene/756499:DESDE_RS05560 ^@ http://purl.uniprot.org/uniprot/I4A6I7 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/756499:DESDE_RS00635 ^@ http://purl.uniprot.org/uniprot/I4A3T8 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/756499:DESDE_RS00605 ^@ http://purl.uniprot.org/uniprot/I4A3T2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/756499:DESDE_RS12315 ^@ http://purl.uniprot.org/uniprot/I4AA82 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/756499:DESDE_RS14740 ^@ http://purl.uniprot.org/uniprot/I4ABK6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/756499:DESDE_RS05460 ^@ http://purl.uniprot.org/uniprot/I4A6G9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/756499:DESDE_RS18485 ^@ http://purl.uniprot.org/uniprot/I4ADP0 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs.|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/756499:DESDE_RS07610 ^@ http://purl.uniprot.org/uniprot/I4A7N3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS08875 ^@ http://purl.uniprot.org/uniprot/I4A8C8 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS19750 ^@ http://purl.uniprot.org/uniprot/I4AED6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/756499:DESDE_RS08390 ^@ http://purl.uniprot.org/uniprot/I4A834 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS19455 ^@ http://purl.uniprot.org/uniprot/I4AE81 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS17105 ^@ http://purl.uniprot.org/uniprot/I4ACX3 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/756499:DESDE_RS02155 ^@ http://purl.uniprot.org/uniprot/I4A4M3 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/756499:DESDE_RS17810 ^@ http://purl.uniprot.org/uniprot/I4ADA9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/756499:DESDE_RS05675 ^@ http://purl.uniprot.org/uniprot/I4A6L0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS04590 ^@ http://purl.uniprot.org/uniprot/I4A5Z2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS04915 ^@ http://purl.uniprot.org/uniprot/I4A656 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS03895 ^@ http://purl.uniprot.org/uniprot/I4A5L0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/756499:DESDE_RS01630 ^@ http://purl.uniprot.org/uniprot/I4A4C0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS18610 ^@ http://purl.uniprot.org/uniprot/I4ADR3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/756499:DESDE_RS09295 ^@ http://purl.uniprot.org/uniprot/I4A8K9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/756499:DESDE_RS09115 ^@ http://purl.uniprot.org/uniprot/I4A8H4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS20345 ^@ http://purl.uniprot.org/uniprot/I4AEQ9 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/756499:DESDE_RS15955 ^@ http://purl.uniprot.org/uniprot/I4AC94 ^@ Function|||PTM|||Similarity|||Subunit ^@ Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.|||Belongs to the peptidase A25 family.|||Homotetramer.|||Initiates the rapid degradation of small, acid-soluble proteins during spore germination. http://togogenome.org/gene/756499:DESDE_RS06130 ^@ http://purl.uniprot.org/uniprot/I4A6V3 ^@ Similarity|||Subunit ^@ Belongs to the beta-eliminating lyase family.|||Homotetramer. http://togogenome.org/gene/756499:DESDE_RS11660 ^@ http://purl.uniprot.org/uniprot/I4A9U8 ^@ Similarity ^@ Belongs to the helicase family. RAD3/XPD subfamily. http://togogenome.org/gene/756499:DESDE_RS17590 ^@ http://purl.uniprot.org/uniprot/I4AD66 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/756499:DESDE_RS03070 ^@ http://purl.uniprot.org/uniprot/I4A546 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/756499:DESDE_RS13215 ^@ http://purl.uniprot.org/uniprot/I4AAQ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/756499:DESDE_RS11620 ^@ http://purl.uniprot.org/uniprot/I4A9U0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS19480 ^@ http://purl.uniprot.org/uniprot/I4AE86 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).|||Belongs to the FGGY kinase family.|||Homotetramer and homodimer (in equilibrium).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/756499:DESDE_RS14335 ^@ http://purl.uniprot.org/uniprot/I4ABC2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/756499:DESDE_RS05480 ^@ http://purl.uniprot.org/uniprot/I4A6H3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS17230 ^@ http://purl.uniprot.org/uniprot/I4ACZ7 ^@ Similarity ^@ Belongs to the bacterial flagellin family. http://togogenome.org/gene/756499:DESDE_RS00025 ^@ http://purl.uniprot.org/uniprot/I4A3H2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/756499:DESDE_RS03185 ^@ http://purl.uniprot.org/uniprot/I4A568 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS18900 ^@ http://purl.uniprot.org/uniprot/I4ADX1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/756499:DESDE_RS19870 ^@ http://purl.uniprot.org/uniprot/I4AEG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS03695 ^@ http://purl.uniprot.org/uniprot/I4A5H0 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/756499:DESDE_RS14735 ^@ http://purl.uniprot.org/uniprot/I4ABK5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/756499:DESDE_RS12060 ^@ http://purl.uniprot.org/uniprot/I4AA30 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/756499:DESDE_RS13075 ^@ http://purl.uniprot.org/uniprot/I4AAM3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS09490 ^@ http://purl.uniprot.org/uniprot/I4A8P9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/756499:DESDE_RS13585 ^@ http://purl.uniprot.org/uniprot/I4AAX4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS00620 ^@ http://purl.uniprot.org/uniprot/I4A3T5 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/756499:DESDE_RS17495 ^@ http://purl.uniprot.org/uniprot/I4AD47 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/756499:DESDE_RS06155 ^@ http://purl.uniprot.org/uniprot/I4A6V8 ^@ Similarity ^@ Belongs to the manganese catalase family. http://togogenome.org/gene/756499:DESDE_RS01860 ^@ http://purl.uniprot.org/uniprot/I4A4G7 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/756499:DESDE_RS19215 ^@ http://purl.uniprot.org/uniprot/I4AE34 ^@ Similarity ^@ Belongs to the YjdM family. http://togogenome.org/gene/756499:DESDE_RS09400 ^@ http://purl.uniprot.org/uniprot/I4A8N0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-C family. DnaE subfamily.|||Cytoplasm|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase. http://togogenome.org/gene/756499:DESDE_RS14805 ^@ http://purl.uniprot.org/uniprot/I4ABL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein SsuA/TauA family.|||Periplasm http://togogenome.org/gene/756499:DESDE_RS17665 ^@ http://purl.uniprot.org/uniprot/I4AD80 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/756499:DESDE_RS05695 ^@ http://purl.uniprot.org/uniprot/I4A6L5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PstS family.|||Cell membrane|||Involved in the system for phosphate transport across the cytoplasmic membrane.|||Membrane|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/756499:DESDE_RS17000 ^@ http://purl.uniprot.org/uniprot/I4ACV2 ^@ Function|||Similarity ^@ Belongs to the CheD family.|||Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis. http://togogenome.org/gene/756499:DESDE_RS17205 ^@ http://purl.uniprot.org/uniprot/I4ACZ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/756499:DESDE_RS16690 ^@ http://purl.uniprot.org/uniprot/I4ACN9 ^@ Similarity ^@ Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/756499:DESDE_RS09735 ^@ http://purl.uniprot.org/uniprot/I4A8V0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS20150 ^@ http://purl.uniprot.org/uniprot/I4AEL8 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/756499:DESDE_RS01855 ^@ http://purl.uniprot.org/uniprot/I4A4G6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/756499:DESDE_RS00055 ^@ http://purl.uniprot.org/uniprot/I4A3H6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS10030 ^@ http://purl.uniprot.org/uniprot/I4A907 ^@ Similarity ^@ Belongs to the flavin oxidoreductase frp family. http://togogenome.org/gene/756499:DESDE_RS02135 ^@ http://purl.uniprot.org/uniprot/I4A4L9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/756499:DESDE_RS14330 ^@ http://purl.uniprot.org/uniprot/I4ABC1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/756499:DESDE_RS04005 ^@ http://purl.uniprot.org/uniprot/I4A5M9 ^@ Similarity ^@ Belongs to the PemK/MazF family. http://togogenome.org/gene/756499:DESDE_RS04885 ^@ http://purl.uniprot.org/uniprot/I4A650 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/756499:DESDE_RS06230 ^@ http://purl.uniprot.org/uniprot/I4A6X4 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/756499:DESDE_RS04785 ^@ http://purl.uniprot.org/uniprot/I4A630 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS16940 ^@ http://purl.uniprot.org/uniprot/I4ACU0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/756499:DESDE_RS01995 ^@ http://purl.uniprot.org/uniprot/I4A4J1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/756499:DESDE_RS15690 ^@ http://purl.uniprot.org/uniprot/I4AC42 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/756499:DESDE_RS01635 ^@ http://purl.uniprot.org/uniprot/I4A4C1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/756499:DESDE_RS11125 ^@ http://purl.uniprot.org/uniprot/I4A9J5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. AddA subfamily.|||Heterodimer of AddA and AddB/RexB.|||The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities. http://togogenome.org/gene/756499:DESDE_RS17380 ^@ http://purl.uniprot.org/uniprot/I4AD25 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS06925 ^@ http://purl.uniprot.org/uniprot/I4A7A7 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/756499:DESDE_RS09725 ^@ http://purl.uniprot.org/uniprot/I4A8U8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS11265 ^@ http://purl.uniprot.org/uniprot/I4A9M4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/756499:DESDE_RS10720 ^@ http://purl.uniprot.org/uniprot/I4A9B2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HupC/HyaC/HydC family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS10105 ^@ http://purl.uniprot.org/uniprot/I4A924 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/756499:DESDE_RS14160 ^@ http://purl.uniprot.org/uniprot/I4AB90 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/756499:DESDE_RS18420 ^@ http://purl.uniprot.org/uniprot/I4ADM7 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/756499:DESDE_RS15720 ^@ http://purl.uniprot.org/uniprot/I4AC48 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/756499:DESDE_RS13190 ^@ http://purl.uniprot.org/uniprot/I4AAP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/756499:DESDE_RS18175 ^@ http://purl.uniprot.org/uniprot/I4ADI2 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/756499:DESDE_RS15150 ^@ http://purl.uniprot.org/uniprot/I4ABT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/756499:DESDE_RS10780 ^@ http://purl.uniprot.org/uniprot/I4A9C5 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/756499:DESDE_RS11725 ^@ http://purl.uniprot.org/uniprot/I4A9W1 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/756499:DESDE_RS08795 ^@ http://purl.uniprot.org/uniprot/I4A8B2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the branched chain amino acid transporter family.|||Cell membrane|||Component of the transport system for branched-chain amino acids.|||Membrane http://togogenome.org/gene/756499:DESDE_RS02010 ^@ http://purl.uniprot.org/uniprot/I4A4J4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/756499:DESDE_RS06720 ^@ http://purl.uniprot.org/uniprot/I4A768 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS13310 ^@ http://purl.uniprot.org/uniprot/I4AAS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0053 family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS19435 ^@ http://purl.uniprot.org/uniprot/I4AE77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS13335 ^@ http://purl.uniprot.org/uniprot/I4AAS6 ^@ Similarity ^@ Belongs to the GerABKA family. http://togogenome.org/gene/756499:DESDE_RS10660 ^@ http://purl.uniprot.org/uniprot/I4A999 ^@ Similarity ^@ Belongs to the CbxX/CfxQ family. http://togogenome.org/gene/756499:DESDE_RS19245 ^@ http://purl.uniprot.org/uniprot/I4AE40 ^@ Caution|||Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS16625 ^@ http://purl.uniprot.org/uniprot/I4ACM5 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/756499:DESDE_RS11015 ^@ http://purl.uniprot.org/uniprot/I4A9H2 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/756499:DESDE_RS12880 ^@ http://purl.uniprot.org/uniprot/I4AAI4 ^@ Similarity ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. http://togogenome.org/gene/756499:DESDE_RS04705 ^@ http://purl.uniprot.org/uniprot/I4A615 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily. http://togogenome.org/gene/756499:DESDE_RS10520 ^@ http://purl.uniprot.org/uniprot/I4A971 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS11130 ^@ http://purl.uniprot.org/uniprot/I4A9J6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the helicase family. AddB/RexB type 1 subfamily.|||Binds 1 [4Fe-4S] cluster.|||Heterodimer of AddA and AddB.|||The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity. http://togogenome.org/gene/756499:DESDE_RS17025 ^@ http://purl.uniprot.org/uniprot/I4ACV7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/756499:DESDE_RS01940 ^@ http://purl.uniprot.org/uniprot/I4A4I3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/756499:DESDE_RS10805 ^@ http://purl.uniprot.org/uniprot/I4A9D1 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/756499:DESDE_RS00610 ^@ http://purl.uniprot.org/uniprot/I4A3T3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/756499:DESDE_RS15965 ^@ http://purl.uniprot.org/uniprot/I4AC96 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/756499:DESDE_RS01595 ^@ http://purl.uniprot.org/uniprot/I4A4B4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/756499:DESDE_RS09510 ^@ http://purl.uniprot.org/uniprot/I4A8Q3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/756499:DESDE_RS10870 ^@ http://purl.uniprot.org/uniprot/I4A9E4 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/756499:DESDE_RS19985 ^@ http://purl.uniprot.org/uniprot/I4AEI5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase A chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/756499:DESDE_RS13225 ^@ http://purl.uniprot.org/uniprot/I4AAQ3 ^@ Function|||Similarity ^@ Belongs to the alpha/beta-type SASP family.|||SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. http://togogenome.org/gene/756499:DESDE_RS03490 ^@ http://purl.uniprot.org/uniprot/I4A5C9 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS08095 ^@ http://purl.uniprot.org/uniprot/I4A7X9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS16665 ^@ http://purl.uniprot.org/uniprot/I4ACN4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS14275 ^@ http://purl.uniprot.org/uniprot/I4ABB0 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/756499:DESDE_RS06420 ^@ http://purl.uniprot.org/uniprot/I4A709 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/756499:DESDE_RS03235 ^@ http://purl.uniprot.org/uniprot/I4A578 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS11640 ^@ http://purl.uniprot.org/uniprot/I4A9U4 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/756499:DESDE_RS11605 ^@ http://purl.uniprot.org/uniprot/I4A9T7 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/756499:DESDE_RS13700 ^@ http://purl.uniprot.org/uniprot/I4AAZ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/756499:DESDE_RS09495 ^@ http://purl.uniprot.org/uniprot/I4A8Q0 ^@ Similarity ^@ Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family. http://togogenome.org/gene/756499:DESDE_RS00005 ^@ http://purl.uniprot.org/uniprot/I4A3G8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/756499:DESDE_RS05680 ^@ http://purl.uniprot.org/uniprot/I4A6L1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/756499:DESDE_RS20090 ^@ http://purl.uniprot.org/uniprot/I4AEK6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS13985 ^@ http://purl.uniprot.org/uniprot/I4AB53 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphopentomutase family.|||Binds 1 or 2 manganese ions.|||Cytoplasm|||Phosphotransfer between the C1 and C5 carbon atoms of pentose. http://togogenome.org/gene/756499:DESDE_RS20435 ^@ http://purl.uniprot.org/uniprot/I4AES6 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/756499:DESDE_RS09110 ^@ http://purl.uniprot.org/uniprot/I4A8H3 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/756499:DESDE_RS17865 ^@ http://purl.uniprot.org/uniprot/I4ADC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS09470 ^@ http://purl.uniprot.org/uniprot/I4A8P6 ^@ Similarity|||Subunit ^@ Belongs to the beta-eliminating lyase family.|||Homotetramer. http://togogenome.org/gene/756499:DESDE_RS14405 ^@ http://purl.uniprot.org/uniprot/I4ABD6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/756499:DESDE_RS08035 ^@ http://purl.uniprot.org/uniprot/I4A7W7 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/756499:DESDE_RS19150 ^@ http://purl.uniprot.org/uniprot/I4AE21 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/756499:DESDE_RS04540 ^@ http://purl.uniprot.org/uniprot/I4A5Y2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-C family. PolC subfamily.|||Cytoplasm|||Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/756499:DESDE_RS19225 ^@ http://purl.uniprot.org/uniprot/I4AE36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS02390 ^@ http://purl.uniprot.org/uniprot/I4A4R4 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS18365 ^@ http://purl.uniprot.org/uniprot/I4ADL6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the methylaspartate mutase GlmS subunit family.|||Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).|||Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer. http://togogenome.org/gene/756499:DESDE_RS14955 ^@ http://purl.uniprot.org/uniprot/I4ABP6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/756499:DESDE_RS18135 ^@ http://purl.uniprot.org/uniprot/I4ADH4 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/756499:DESDE_RS03755 ^@ http://purl.uniprot.org/uniprot/I4A5I3 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS07130 ^@ http://purl.uniprot.org/uniprot/I4AAG9 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/756499:DESDE_RS11445 ^@ http://purl.uniprot.org/uniprot/I4A9Q4 ^@ Similarity ^@ Belongs to the CvfB family. http://togogenome.org/gene/756499:DESDE_RS00400 ^@ http://purl.uniprot.org/uniprot/I4A3P2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS17650 ^@ http://purl.uniprot.org/uniprot/I4AD77 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/756499:DESDE_RS00270 ^@ http://purl.uniprot.org/uniprot/I4A3L7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS10655 ^@ http://purl.uniprot.org/uniprot/I4A998 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/756499:DESDE_RS06240 ^@ http://purl.uniprot.org/uniprot/I4A6X6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CobB/CobQ family. GatD subfamily.|||Forms a heterodimer with MurT.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT. http://togogenome.org/gene/756499:DESDE_RS00555 ^@ http://purl.uniprot.org/uniprot/I4A3S3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/756499:DESDE_RS20260 ^@ http://purl.uniprot.org/uniprot/I4AEP1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS14415 ^@ http://purl.uniprot.org/uniprot/I4ABD8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS06365 ^@ http://purl.uniprot.org/uniprot/I4A6Z8 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/756499:DESDE_RS14195 ^@ http://purl.uniprot.org/uniprot/I4AB97 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/756499:DESDE_RS16005 ^@ http://purl.uniprot.org/uniprot/I4ACA4 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS15025 ^@ http://purl.uniprot.org/uniprot/I4ABQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS00565 ^@ http://purl.uniprot.org/uniprot/I4A3S5 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/756499:DESDE_RS20250 ^@ http://purl.uniprot.org/uniprot/I4AEN9 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/756499:DESDE_RS06470 ^@ http://purl.uniprot.org/uniprot/I4A718 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/756499:DESDE_RS00585 ^@ http://purl.uniprot.org/uniprot/I4A3S8 ^@ Similarity ^@ Belongs to the DHPS family. http://togogenome.org/gene/756499:DESDE_RS19975 ^@ http://purl.uniprot.org/uniprot/I4AEI3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/756499:DESDE_RS07670 ^@ http://purl.uniprot.org/uniprot/I4A7P4 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. http://togogenome.org/gene/756499:DESDE_RS09310 ^@ http://purl.uniprot.org/uniprot/I4A8L2 ^@ Similarity ^@ Belongs to the diacylglycerol/lipid kinase family. http://togogenome.org/gene/756499:DESDE_RS03510 ^@ http://purl.uniprot.org/uniprot/I4A5D3 ^@ Similarity ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family. http://togogenome.org/gene/756499:DESDE_RS14715 ^@ http://purl.uniprot.org/uniprot/I4ABK1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/756499:DESDE_RS20600 ^@ http://purl.uniprot.org/uniprot/I4AEV7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/756499:DESDE_RS05485 ^@ http://purl.uniprot.org/uniprot/I4A6H4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS18785 ^@ http://purl.uniprot.org/uniprot/I4ADU7 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/756499:DESDE_RS20690 ^@ http://purl.uniprot.org/uniprot/I4AEX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS18440 ^@ http://purl.uniprot.org/uniprot/I4ADN1 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/756499:DESDE_RS04810 ^@ http://purl.uniprot.org/uniprot/I4A635 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/756499:DESDE_RS15680 ^@ http://purl.uniprot.org/uniprot/I4AC40 ^@ Function|||Similarity ^@ Belongs to the complex I 30 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/756499:DESDE_RS00360 ^@ http://purl.uniprot.org/uniprot/I4A3N5 ^@ Function|||Similarity|||Subunit ^@ Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).|||Homodimer.|||In the C-terminal section; belongs to the MurCDEF family. http://togogenome.org/gene/756499:DESDE_RS09795 ^@ http://purl.uniprot.org/uniprot/I4A8W1 ^@ Function|||Similarity ^@ Belongs to the Thz kinase family.|||Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ). http://togogenome.org/gene/756499:DESDE_RS00895 ^@ http://purl.uniprot.org/uniprot/I4A3Y1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS02125 ^@ http://purl.uniprot.org/uniprot/I4A4L7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/756499:DESDE_RS17080 ^@ http://purl.uniprot.org/uniprot/I4ACW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS03250 ^@ http://purl.uniprot.org/uniprot/I4A581 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/756499:DESDE_RS05835 ^@ http://purl.uniprot.org/uniprot/I4A6P4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS08080 ^@ http://purl.uniprot.org/uniprot/I4A7X6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/756499:DESDE_RS03080 ^@ http://purl.uniprot.org/uniprot/I4A548 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/756499:DESDE_RS02375 ^@ http://purl.uniprot.org/uniprot/I4A4R1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS12765 ^@ http://purl.uniprot.org/uniprot/I4AAG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial glucokinase family.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS15060 ^@ http://purl.uniprot.org/uniprot/I4ABR5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS13955 ^@ http://purl.uniprot.org/uniprot/I4AB47 ^@ Function|||Similarity ^@ Belongs to the anti-sigma-factor family.|||Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. http://togogenome.org/gene/756499:DESDE_RS15030 ^@ http://purl.uniprot.org/uniprot/I4ABQ9 ^@ Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/756499:DESDE_RS03095 ^@ http://purl.uniprot.org/uniprot/I4A551 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. http://togogenome.org/gene/756499:DESDE_RS13605 ^@ http://purl.uniprot.org/uniprot/I4AAX8 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/756499:DESDE_RS14455 ^@ http://purl.uniprot.org/uniprot/I4ABE6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/756499:DESDE_RS20280 ^@ http://purl.uniprot.org/uniprot/I4AEP5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/756499:DESDE_RS16180 ^@ http://purl.uniprot.org/uniprot/I4ACE0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS16835 ^@ http://purl.uniprot.org/uniprot/I4ACR9 ^@ Similarity ^@ Belongs to the PHP hydrolase family. HisK subfamily. http://togogenome.org/gene/756499:DESDE_RS11900 ^@ http://purl.uniprot.org/uniprot/I4A9Z9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BBS4 family.|||Membrane|||centrosome|||cilium membrane http://togogenome.org/gene/756499:DESDE_RS01935 ^@ http://purl.uniprot.org/uniprot/I4A4I2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS09450 ^@ http://purl.uniprot.org/uniprot/I4A8P2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS19255 ^@ http://purl.uniprot.org/uniprot/I4AE42 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS16235 ^@ http://purl.uniprot.org/uniprot/I4ACF1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS11085 ^@ http://purl.uniprot.org/uniprot/I4A9I7 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/756499:DESDE_RS19690 ^@ http://purl.uniprot.org/uniprot/I4AEC5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/756499:DESDE_RS09380 ^@ http://purl.uniprot.org/uniprot/I4A8M5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS03850 ^@ http://purl.uniprot.org/uniprot/I4A5K2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS11315 ^@ http://purl.uniprot.org/uniprot/I4A9N3 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/756499:DESDE_RS15020 ^@ http://purl.uniprot.org/uniprot/I4ABQ7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/756499:DESDE_RS02085 ^@ http://purl.uniprot.org/uniprot/I4A4K9 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/756499:DESDE_RS11255 ^@ http://purl.uniprot.org/uniprot/I4A9M2 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/756499:DESDE_RS04900 ^@ http://purl.uniprot.org/uniprot/I4A653 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmB/CycW/HelB family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS18080 ^@ http://purl.uniprot.org/uniprot/I4ADG3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/756499:DESDE_RS13260 ^@ http://purl.uniprot.org/uniprot/I4AAR1 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/756499:DESDE_RS10820 ^@ http://purl.uniprot.org/uniprot/I4A9D4 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/756499:DESDE_RS10640 ^@ http://purl.uniprot.org/uniprot/I4A995 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS03560 ^@ http://purl.uniprot.org/uniprot/I4A5E3 ^@ Function|||Subunit ^@ Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/756499:DESDE_RS02260 ^@ http://purl.uniprot.org/uniprot/I4A4P2 ^@ Caution|||Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS00175 ^@ http://purl.uniprot.org/uniprot/I4A3J8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/756499:DESDE_RS03675 ^@ http://purl.uniprot.org/uniprot/I4A5G6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS16980 ^@ http://purl.uniprot.org/uniprot/I4ACU8 ^@ Similarity ^@ Belongs to the FlgD family. http://togogenome.org/gene/756499:DESDE_RS03630 ^@ http://purl.uniprot.org/uniprot/I4A5F7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS15865 ^@ http://purl.uniprot.org/uniprot/I4AC76 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/756499:DESDE_RS00430 ^@ http://purl.uniprot.org/uniprot/I4A3P8 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS16845 ^@ http://purl.uniprot.org/uniprot/I4ACS1 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/756499:DESDE_RS10865 ^@ http://purl.uniprot.org/uniprot/I4A9E3 ^@ Similarity ^@ Belongs to the ETF-QO/FixC family. http://togogenome.org/gene/756499:DESDE_RS13545 ^@ http://purl.uniprot.org/uniprot/I4AAW6 ^@ Similarity ^@ Belongs to the Ahb/Nir family. http://togogenome.org/gene/756499:DESDE_RS02980 ^@ http://purl.uniprot.org/uniprot/I4A528 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/756499:DESDE_RS04565 ^@ http://purl.uniprot.org/uniprot/I4A5Y7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS14500 ^@ http://purl.uniprot.org/uniprot/I4ABF5 ^@ Similarity ^@ Belongs to the UPF0297 family. http://togogenome.org/gene/756499:DESDE_RS10270 ^@ http://purl.uniprot.org/uniprot/I4A927 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiM family.|||Cell membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Membrane|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/756499:DESDE_RS10605 ^@ http://purl.uniprot.org/uniprot/I4A988 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/756499:DESDE_RS19470 ^@ http://purl.uniprot.org/uniprot/I4AE84 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS06220 ^@ http://purl.uniprot.org/uniprot/I4A6X2 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/756499:DESDE_RS01050 ^@ http://purl.uniprot.org/uniprot/I4A411 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Cell membrane|||Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS17940 ^@ http://purl.uniprot.org/uniprot/I4ADD5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS04450 ^@ http://purl.uniprot.org/uniprot/I4A5W4 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/756499:DESDE_RS15765 ^@ http://purl.uniprot.org/uniprot/I4AC56 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/756499:DESDE_RS02120 ^@ http://purl.uniprot.org/uniprot/I4A4L6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/756499:DESDE_RS14890 ^@ http://purl.uniprot.org/uniprot/I4ABN3 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/756499:DESDE_RS17300 ^@ http://purl.uniprot.org/uniprot/I4AD11 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/756499:DESDE_RS12075 ^@ http://purl.uniprot.org/uniprot/I4AA33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS13565 ^@ http://purl.uniprot.org/uniprot/I4AAX0 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/756499:DESDE_RS09375 ^@ http://purl.uniprot.org/uniprot/I4A8M4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS18840 ^@ http://purl.uniprot.org/uniprot/I4ADV9 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters.|||Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. http://togogenome.org/gene/756499:DESDE_RS19855 ^@ http://purl.uniprot.org/uniprot/I4AEF9 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS15655 ^@ http://purl.uniprot.org/uniprot/I4AC35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.|||Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/756499:DESDE_RS04980 ^@ http://purl.uniprot.org/uniprot/I4A669 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.|||Binds 1 Mn(2+) ion per subunit.|||Cytoplasm|||Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. http://togogenome.org/gene/756499:DESDE_RS20135 ^@ http://purl.uniprot.org/uniprot/I4AEL5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS06145 ^@ http://purl.uniprot.org/uniprot/I4A6V6 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/756499:DESDE_RS09535 ^@ http://purl.uniprot.org/uniprot/I4A8Q8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS14460 ^@ http://purl.uniprot.org/uniprot/I4ABE7 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/756499:DESDE_RS19170 ^@ http://purl.uniprot.org/uniprot/I4AE25 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the selenophosphate synthase 1 family. Class I subfamily.|||Binds 1 Mg(2+) ion per monomer.|||Homodimer.|||Synthesizes selenophosphate from selenide and ATP. http://togogenome.org/gene/756499:DESDE_RS01700 ^@ http://purl.uniprot.org/uniprot/I4A4D4 ^@ Similarity ^@ Belongs to the CarB family. http://togogenome.org/gene/756499:DESDE_RS16185 ^@ http://purl.uniprot.org/uniprot/I4ACE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS17920 ^@ http://purl.uniprot.org/uniprot/I4ADD1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS16550 ^@ http://purl.uniprot.org/uniprot/I4ACL1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. N-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/756499:DESDE_RS15740 ^@ http://purl.uniprot.org/uniprot/I4AC51 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/756499:DESDE_RS01360 ^@ http://purl.uniprot.org/uniprot/I4A468 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/756499:DESDE_RS12185 ^@ http://purl.uniprot.org/uniprot/I4AA55 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/756499:DESDE_RS18170 ^@ http://purl.uniprot.org/uniprot/I4ADI1 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/756499:DESDE_RS15050 ^@ http://purl.uniprot.org/uniprot/I4ABR3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/756499:DESDE_RS01520 ^@ http://purl.uniprot.org/uniprot/I4A499 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/756499:DESDE_RS14620 ^@ http://purl.uniprot.org/uniprot/I4ABI1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/756499:DESDE_RS07515 ^@ http://purl.uniprot.org/uniprot/I4A7L5 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/756499:DESDE_RS05855 ^@ http://purl.uniprot.org/uniprot/I4A6P8 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS16215 ^@ http://purl.uniprot.org/uniprot/I4ACE7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/756499:DESDE_RS15805 ^@ http://purl.uniprot.org/uniprot/I4AC64 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane|||This protein catalyzes the committed step to the synthesis of the acidic phospholipids. http://togogenome.org/gene/756499:DESDE_RS14525 ^@ http://purl.uniprot.org/uniprot/I4ABG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS14560 ^@ http://purl.uniprot.org/uniprot/I4ABG8 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/756499:DESDE_RS07780 ^@ http://purl.uniprot.org/uniprot/I4A7R6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS18995 ^@ http://purl.uniprot.org/uniprot/I4ADZ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS01080 ^@ http://purl.uniprot.org/uniprot/I4A414 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/756499:DESDE_RS20420 ^@ http://purl.uniprot.org/uniprot/I4AES3 ^@ Function|||PTM|||Similarity ^@ Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily.|||Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde.|||Requires the activating protein CutD to generate the key active site glycyl radical on Gly-823 that is involved in catalysis. http://togogenome.org/gene/756499:DESDE_RS18895 ^@ http://purl.uniprot.org/uniprot/I4ADX0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetyl-CoA hydrolase/transferase family.|||Coenzyme A-transferase that converts butyrate to butyryl-CoA.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS07775 ^@ http://purl.uniprot.org/uniprot/I4A7R5 ^@ Similarity ^@ Belongs to the UPF0251 family. http://togogenome.org/gene/756499:DESDE_RS01960 ^@ http://purl.uniprot.org/uniprot/I4A4I6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MrnC RNase family.|||Cytoplasm|||Homodimer.|||Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors. http://togogenome.org/gene/756499:DESDE_RS12510 ^@ http://purl.uniprot.org/uniprot/I4AAC3 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/756499:DESDE_RS17835 ^@ http://purl.uniprot.org/uniprot/I4ADB4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/756499:DESDE_RS18125 ^@ http://purl.uniprot.org/uniprot/I4ADH2 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/756499:DESDE_RS09650 ^@ http://purl.uniprot.org/uniprot/I4A8T1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS15460 ^@ http://purl.uniprot.org/uniprot/I4ABZ7 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/756499:DESDE_RS19575 ^@ http://purl.uniprot.org/uniprot/I4AEA5 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Requires K(+) for maximal activity.|||Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. http://togogenome.org/gene/756499:DESDE_RS02695 ^@ http://purl.uniprot.org/uniprot/I4A4X6 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/756499:DESDE_RS17040 ^@ http://purl.uniprot.org/uniprot/U3GJK0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/756499:DESDE_RS06920 ^@ http://purl.uniprot.org/uniprot/I4A7A6 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS15895 ^@ http://purl.uniprot.org/uniprot/I4AC82 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/756499:DESDE_RS16010 ^@ http://purl.uniprot.org/uniprot/I4ACA5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/756499:DESDE_RS09475 ^@ http://purl.uniprot.org/uniprot/I4A8P7 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/756499:DESDE_RS20535 ^@ http://purl.uniprot.org/uniprot/I4AEU5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS00815 ^@ http://purl.uniprot.org/uniprot/I4A3W4 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS00570 ^@ http://purl.uniprot.org/uniprot/I4A3S6 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/756499:DESDE_RS20455 ^@ http://purl.uniprot.org/uniprot/I4AET0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/756499:DESDE_RS19680 ^@ http://purl.uniprot.org/uniprot/I4AEC4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/756499:DESDE_RS17610 ^@ http://purl.uniprot.org/uniprot/I4AD70 ^@ Function ^@ Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP. http://togogenome.org/gene/756499:DESDE_RS15930 ^@ http://purl.uniprot.org/uniprot/I4AC89 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/756499:DESDE_RS17220 ^@ http://purl.uniprot.org/uniprot/I4ACZ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.|||Belongs to the FliW family.|||Cytoplasm|||Interacts with translational regulator CsrA and flagellin(s). http://togogenome.org/gene/756499:DESDE_RS19115 ^@ http://purl.uniprot.org/uniprot/I4AE14 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS14270 ^@ http://purl.uniprot.org/uniprot/I4ABA9 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/756499:DESDE_RS08040 ^@ http://purl.uniprot.org/uniprot/I4A7W8 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS08600 ^@ http://purl.uniprot.org/uniprot/I4A873 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS20170 ^@ http://purl.uniprot.org/uniprot/I4AEM2 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/756499:DESDE_RS00230 ^@ http://purl.uniprot.org/uniprot/I4A3K9 ^@ Similarity ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family. http://togogenome.org/gene/756499:DESDE_RS17745 ^@ http://purl.uniprot.org/uniprot/I4AD96 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/756499:DESDE_RS15745 ^@ http://purl.uniprot.org/uniprot/I4AC52 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/756499:DESDE_RS08800 ^@ http://purl.uniprot.org/uniprot/I4A8B3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/756499:DESDE_RS10945 ^@ http://purl.uniprot.org/uniprot/I4A9F9 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/756499:DESDE_RS03700 ^@ http://purl.uniprot.org/uniprot/I4A5H1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/756499:DESDE_RS12365 ^@ http://purl.uniprot.org/uniprot/I4AA93 ^@ Cofactor|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit. http://togogenome.org/gene/756499:DESDE_RS20480 ^@ http://purl.uniprot.org/uniprot/I4AET5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/756499:DESDE_RS08900 ^@ http://purl.uniprot.org/uniprot/I4A8D3 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/756499:DESDE_RS05830 ^@ http://purl.uniprot.org/uniprot/I4A6P3 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/756499:DESDE_RS09560 ^@ http://purl.uniprot.org/uniprot/I4A8R3 ^@ Similarity ^@ Belongs to the isochorismate synthase family. http://togogenome.org/gene/756499:DESDE_RS05820 ^@ http://purl.uniprot.org/uniprot/I4A6P1 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/756499:DESDE_RS16220 ^@ http://purl.uniprot.org/uniprot/I4ACE8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/756499:DESDE_RS05990 ^@ http://purl.uniprot.org/uniprot/I4A6S4 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/756499:DESDE_RS09195 ^@ http://purl.uniprot.org/uniprot/I4A8J0 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/756499:DESDE_RS11680 ^@ http://purl.uniprot.org/uniprot/I4A9V2 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/756499:DESDE_RS02045 ^@ http://purl.uniprot.org/uniprot/I4A4K1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/756499:DESDE_RS19450 ^@ http://purl.uniprot.org/uniprot/I4AE80 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS16760 ^@ http://purl.uniprot.org/uniprot/I4ACQ3 ^@ Similarity ^@ Belongs to the transpeptidase family. http://togogenome.org/gene/756499:DESDE_RS08175 ^@ http://purl.uniprot.org/uniprot/I4A7Z5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS13275 ^@ http://purl.uniprot.org/uniprot/I4AAR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS05720 ^@ http://purl.uniprot.org/uniprot/I4A6M0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Amj family.|||Cell membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. http://togogenome.org/gene/756499:DESDE_RS15875 ^@ http://purl.uniprot.org/uniprot/I4AC78 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/756499:DESDE_RS16055 ^@ http://purl.uniprot.org/uniprot/I4ACB4 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/756499:DESDE_RS12345 ^@ http://purl.uniprot.org/uniprot/I4AA89 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/756499:DESDE_RS01485 ^@ http://purl.uniprot.org/uniprot/I4A492 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/756499:DESDE_RS08845 ^@ http://purl.uniprot.org/uniprot/I4A8C2 ^@ Similarity ^@ Belongs to the GerABKC lipoprotein family. http://togogenome.org/gene/756499:DESDE_RS13625 ^@ http://purl.uniprot.org/uniprot/I4AAY2 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/756499:DESDE_RS20440 ^@ http://purl.uniprot.org/uniprot/I4AES7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS04815 ^@ http://purl.uniprot.org/uniprot/I4A636 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/756499:DESDE_RS02080 ^@ http://purl.uniprot.org/uniprot/I4A4K8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/756499:DESDE_RS12190 ^@ http://purl.uniprot.org/uniprot/I4AA57 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/756499:DESDE_RS02330 ^@ http://purl.uniprot.org/uniprot/I4A4Q5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS16960 ^@ http://purl.uniprot.org/uniprot/I4ACU4 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/756499:DESDE_RS17140 ^@ http://purl.uniprot.org/uniprot/U3GK07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/756499:DESDE_RS15090 ^@ http://purl.uniprot.org/uniprot/I4ABS1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/756499:DESDE_RS20190 ^@ http://purl.uniprot.org/uniprot/I4AEM6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/756499:DESDE_RS10095 ^@ http://purl.uniprot.org/uniprot/I4A922 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/756499:DESDE_RS19265 ^@ http://purl.uniprot.org/uniprot/I4AE44 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS16075 ^@ http://purl.uniprot.org/uniprot/I4ACB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS10365 ^@ http://purl.uniprot.org/uniprot/I4A939 ^@ Caution|||Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Belongs to the MsrB Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.|||In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.|||In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS20590 ^@ http://purl.uniprot.org/uniprot/I4AEV5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/756499:DESDE_RS01625 ^@ http://purl.uniprot.org/uniprot/I4A4B9 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/756499:DESDE_RS19110 ^@ http://purl.uniprot.org/uniprot/I4AE13 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/756499:DESDE_RS02600 ^@ http://purl.uniprot.org/uniprot/I4A4V6 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/756499:DESDE_RS09575 ^@ http://purl.uniprot.org/uniprot/I4A8R6 ^@ Function|||Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.|||Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA). http://togogenome.org/gene/756499:DESDE_RS03265 ^@ http://purl.uniprot.org/uniprot/I4A584 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS03285 ^@ http://purl.uniprot.org/uniprot/I4A587 ^@ Similarity|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.|||Heterodimer of a large and a small subunit. http://togogenome.org/gene/756499:DESDE_RS15990 ^@ http://purl.uniprot.org/uniprot/I4ACA1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/756499:DESDE_RS18220 ^@ http://purl.uniprot.org/uniprot/I4ADJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS02565 ^@ http://purl.uniprot.org/uniprot/I4A4U9 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/756499:DESDE_RS18115 ^@ http://purl.uniprot.org/uniprot/I4ADH0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS13725 ^@ http://purl.uniprot.org/uniprot/I4AB00 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/756499:DESDE_RS05500 ^@ http://purl.uniprot.org/uniprot/I4A6H7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS13305 ^@ http://purl.uniprot.org/uniprot/I4AAS0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS13950 ^@ http://purl.uniprot.org/uniprot/I4AB46 ^@ Function|||Similarity ^@ Belongs to the anti-sigma-factor antagonist family.|||In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition. http://togogenome.org/gene/756499:DESDE_RS18935 ^@ http://purl.uniprot.org/uniprot/I4ADX8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/756499:DESDE_RS09700 ^@ http://purl.uniprot.org/uniprot/I4A8U2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS15640 ^@ http://purl.uniprot.org/uniprot/I4AC32 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/756499:DESDE_RS13720 ^@ http://purl.uniprot.org/uniprot/I4AAZ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS16785 ^@ http://purl.uniprot.org/uniprot/I4ACQ8 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/756499:DESDE_RS11500 ^@ http://purl.uniprot.org/uniprot/I4A9R5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/756499:DESDE_RS16920 ^@ http://purl.uniprot.org/uniprot/I4ACT6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS06400 ^@ http://purl.uniprot.org/uniprot/I4A705 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/756499:DESDE_RS13350 ^@ http://purl.uniprot.org/uniprot/I4AAS9 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/756499:DESDE_RS18480 ^@ http://purl.uniprot.org/uniprot/I4ADN9 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/756499:DESDE_RS20175 ^@ http://purl.uniprot.org/uniprot/I4AEM3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/756499:DESDE_RS20675 ^@ http://purl.uniprot.org/uniprot/I4AEX2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/756499:DESDE_RS12045 ^@ http://purl.uniprot.org/uniprot/I4AA28 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS05575 ^@ http://purl.uniprot.org/uniprot/I4A6I9 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.|||Binds 2 Zn(2+) ions per subunit.|||Carboxylation allows a single lysine to coordinate two zinc ions.|||Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.|||Homotetramer. http://togogenome.org/gene/756499:DESDE_RS01310 ^@ http://purl.uniprot.org/uniprot/I4A457 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS10840 ^@ http://purl.uniprot.org/uniprot/I4A9D8 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/756499:DESDE_RS10940 ^@ http://purl.uniprot.org/uniprot/I4A9F8 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS19335 ^@ http://purl.uniprot.org/uniprot/I4AE56 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS11970 ^@ http://purl.uniprot.org/uniprot/I4AA13 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/756499:DESDE_RS00625 ^@ http://purl.uniprot.org/uniprot/I4A3T6 ^@ Caution|||Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.|||Belongs to the biotin--protein ligase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS13540 ^@ http://purl.uniprot.org/uniprot/I4AAW5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS01710 ^@ http://purl.uniprot.org/uniprot/I4A4D7 ^@ Function|||Similarity ^@ Belongs to the PduL family.|||Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. http://togogenome.org/gene/756499:DESDE_RS01245 ^@ http://purl.uniprot.org/uniprot/I4A443 ^@ Similarity ^@ Belongs to the GerABKA family. http://togogenome.org/gene/756499:DESDE_RS16575 ^@ http://purl.uniprot.org/uniprot/I4ACL5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/756499:DESDE_RS20215 ^@ http://purl.uniprot.org/uniprot/I4AEN1 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/756499:DESDE_RS12635 ^@ http://purl.uniprot.org/uniprot/I4AAE8 ^@ Similarity ^@ Belongs to the xanthine dehydrogenase family. http://togogenome.org/gene/756499:DESDE_RS18825 ^@ http://purl.uniprot.org/uniprot/I4ADV6 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/756499:DESDE_RS13495 ^@ http://purl.uniprot.org/uniprot/I4AAV6 ^@ Function|||Similarity ^@ Belongs to the LarC family.|||Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. http://togogenome.org/gene/756499:DESDE_RS04580 ^@ http://purl.uniprot.org/uniprot/I4A5Z0 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/756499:DESDE_RS04615 ^@ http://purl.uniprot.org/uniprot/I4A5Z7 ^@ Similarity ^@ Belongs to the ETF-QO/FixC family. http://togogenome.org/gene/756499:DESDE_RS19955 ^@ http://purl.uniprot.org/uniprot/I4AEH9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/756499:DESDE_RS08360 ^@ http://purl.uniprot.org/uniprot/I4A828 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS07685 ^@ http://purl.uniprot.org/uniprot/I4A7P7 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS02105 ^@ http://purl.uniprot.org/uniprot/I4A4L3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/756499:DESDE_RS20615 ^@ http://purl.uniprot.org/uniprot/I4AEW0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS03645 ^@ http://purl.uniprot.org/uniprot/I4A5G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS11645 ^@ http://purl.uniprot.org/uniprot/I4A9U5 ^@ Similarity ^@ Belongs to the RNase H family. http://togogenome.org/gene/756499:DESDE_RS06930 ^@ http://purl.uniprot.org/uniprot/I4A7A8 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/756499:DESDE_RS09305 ^@ http://purl.uniprot.org/uniprot/I4A8L1 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/756499:DESDE_RS11175 ^@ http://purl.uniprot.org/uniprot/I4A9K5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CotF family.|||Spore coat http://togogenome.org/gene/756499:DESDE_RS17825 ^@ http://purl.uniprot.org/uniprot/I4ADB2 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS13965 ^@ http://purl.uniprot.org/uniprot/I4AB49 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/756499:DESDE_RS14505 ^@ http://purl.uniprot.org/uniprot/I4ABF6 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS01125 ^@ http://purl.uniprot.org/uniprot/I4A423 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0394 family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS19015 ^@ http://purl.uniprot.org/uniprot/I4ADZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS02095 ^@ http://purl.uniprot.org/uniprot/I4A4L1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/756499:DESDE_RS01225 ^@ http://purl.uniprot.org/uniprot/I4A439 ^@ Similarity ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family. http://togogenome.org/gene/756499:DESDE_RS17595 ^@ http://purl.uniprot.org/uniprot/I4AD67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/756499:DESDE_RS09565 ^@ http://purl.uniprot.org/uniprot/I4A8R4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the TPP enzyme family. MenD subfamily.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS18070 ^@ http://purl.uniprot.org/uniprot/I4ADG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS18925 ^@ http://purl.uniprot.org/uniprot/I4ADX6 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/756499:DESDE_RS04480 ^@ http://purl.uniprot.org/uniprot/I4A5X0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS20370 ^@ http://purl.uniprot.org/uniprot/I4AER4 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/756499:DESDE_RS03545 ^@ http://purl.uniprot.org/uniprot/I4A5E0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/756499:DESDE_RS05595 ^@ http://purl.uniprot.org/uniprot/I4A6J3 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/756499:DESDE_RS09820 ^@ http://purl.uniprot.org/uniprot/I4A8W6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS11565 ^@ http://purl.uniprot.org/uniprot/I4A9S8 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/756499:DESDE_RS17720 ^@ http://purl.uniprot.org/uniprot/I4AD91 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS13355 ^@ http://purl.uniprot.org/uniprot/I4AAT0 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/756499:DESDE_RS18050 ^@ http://purl.uniprot.org/uniprot/I4ADF7 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/756499:DESDE_RS03965 ^@ http://purl.uniprot.org/uniprot/I4A5M3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS18105 ^@ http://purl.uniprot.org/uniprot/I4ADG8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/756499:DESDE_RS03215 ^@ http://purl.uniprot.org/uniprot/I4A574 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS07570 ^@ http://purl.uniprot.org/uniprot/I4A7M5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS02705 ^@ http://purl.uniprot.org/uniprot/I4A4X8 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/756499:DESDE_RS18355 ^@ http://purl.uniprot.org/uniprot/I4ADL4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the methylaspartate mutase GlmE subunit family.|||Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).|||Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer. http://togogenome.org/gene/756499:DESDE_RS06215 ^@ http://purl.uniprot.org/uniprot/I4A6X1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS19805 ^@ http://purl.uniprot.org/uniprot/I4AEE8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS06465 ^@ http://purl.uniprot.org/uniprot/I4A717 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/756499:DESDE_RS15795 ^@ http://purl.uniprot.org/uniprot/I4AC62 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/756499:DESDE_RS02280 ^@ http://purl.uniprot.org/uniprot/I4A4P6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS18905 ^@ http://purl.uniprot.org/uniprot/I4ADX2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/756499:DESDE_RS18075 ^@ http://purl.uniprot.org/uniprot/I4ADG2 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/756499:DESDE_RS00170 ^@ http://purl.uniprot.org/uniprot/I4A3J7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/756499:DESDE_RS10850 ^@ http://purl.uniprot.org/uniprot/I4A9E0 ^@ Similarity ^@ Belongs to the transpeptidase family. http://togogenome.org/gene/756499:DESDE_RS17965 ^@ http://purl.uniprot.org/uniprot/I4ADE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS12530 ^@ http://purl.uniprot.org/uniprot/I4AAC7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane|||This protein catalyzes the committed step to the synthesis of the acidic phospholipids. http://togogenome.org/gene/756499:DESDE_RS00630 ^@ http://purl.uniprot.org/uniprot/I4A3T7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS17995 ^@ http://purl.uniprot.org/uniprot/I4ADE6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/756499:DESDE_RS09365 ^@ http://purl.uniprot.org/uniprot/I4A8M2 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/756499:DESDE_RS06030 ^@ http://purl.uniprot.org/uniprot/I4A6T2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/756499:DESDE_RS19315 ^@ http://purl.uniprot.org/uniprot/I4AE52 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS17215 ^@ http://purl.uniprot.org/uniprot/I4ACZ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/756499:DESDE_RS09260 ^@ http://purl.uniprot.org/uniprot/I4A8K3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS08635 ^@ http://purl.uniprot.org/uniprot/I4A880 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/756499:DESDE_RS14920 ^@ http://purl.uniprot.org/uniprot/I4ABN9 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/756499:DESDE_RS13705 ^@ http://purl.uniprot.org/uniprot/I4AAZ6 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/756499:DESDE_RS01270 ^@ http://purl.uniprot.org/uniprot/I4A449 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS10040 ^@ http://purl.uniprot.org/uniprot/I4A909 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS00380 ^@ http://purl.uniprot.org/uniprot/I4A3N8 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/756499:DESDE_RS05050 ^@ http://purl.uniprot.org/uniprot/I4A683 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS14665 ^@ http://purl.uniprot.org/uniprot/I4ABI9 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/756499:DESDE_RS06895 ^@ http://purl.uniprot.org/uniprot/I4A7A1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS04500 ^@ http://purl.uniprot.org/uniprot/I4A5X4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.|||Homotetramer. http://togogenome.org/gene/756499:DESDE_RS08540 ^@ http://purl.uniprot.org/uniprot/I4A861 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS13125 ^@ http://purl.uniprot.org/uniprot/I4AAN3 ^@ Similarity ^@ Belongs to the type IA topoisomerase family. http://togogenome.org/gene/756499:DESDE_RS11895 ^@ http://purl.uniprot.org/uniprot/I4A9Z8 ^@ Function|||Similarity ^@ Belongs to the transposase IS30 family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/756499:DESDE_RS14490 ^@ http://purl.uniprot.org/uniprot/I4ABF3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS03150 ^@ http://purl.uniprot.org/uniprot/I4A561 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS19495 ^@ http://purl.uniprot.org/uniprot/I4AE89 ^@ Similarity ^@ Belongs to the UPF0751 family. http://togogenome.org/gene/756499:DESDE_RS16600 ^@ http://purl.uniprot.org/uniprot/I4ACM0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/756499:DESDE_RS08575 ^@ http://purl.uniprot.org/uniprot/I4A868 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/756499:DESDE_RS11270 ^@ http://purl.uniprot.org/uniprot/I4A9M5 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/756499:DESDE_RS12890 ^@ http://purl.uniprot.org/uniprot/I4AAI6 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/756499:DESDE_RS01905 ^@ http://purl.uniprot.org/uniprot/I4A4H6 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/756499:DESDE_RS09120 ^@ http://purl.uniprot.org/uniprot/I4A8H5 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/756499:DESDE_RS00645 ^@ http://purl.uniprot.org/uniprot/I4A3U0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS09265 ^@ http://purl.uniprot.org/uniprot/I4A8K4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS02040 ^@ http://purl.uniprot.org/uniprot/I4A4K0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/756499:DESDE_RS11155 ^@ http://purl.uniprot.org/uniprot/I4A9K1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/756499:DESDE_RS02930 ^@ http://purl.uniprot.org/uniprot/I4A517 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS00710 ^@ http://purl.uniprot.org/uniprot/I4A3U8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/756499:DESDE_RS14710 ^@ http://purl.uniprot.org/uniprot/I4ABK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS19965 ^@ http://purl.uniprot.org/uniprot/I4AEI1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/756499:DESDE_RS01135 ^@ http://purl.uniprot.org/uniprot/I4A425 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0394 family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS05705 ^@ http://purl.uniprot.org/uniprot/I4A6L7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS09465 ^@ http://purl.uniprot.org/uniprot/I4A8P5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS10575 ^@ http://purl.uniprot.org/uniprot/I4A982 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/756499:DESDE_RS20545 ^@ http://purl.uniprot.org/uniprot/I4AEU7 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/756499:DESDE_RS10385 ^@ http://purl.uniprot.org/uniprot/I4A943 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/756499:DESDE_RS06795 ^@ http://purl.uniprot.org/uniprot/I4A781 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/756499:DESDE_RS14950 ^@ http://purl.uniprot.org/uniprot/I4ABP5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/756499:DESDE_RS09605 ^@ http://purl.uniprot.org/uniprot/I4A8S2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS18190 ^@ http://purl.uniprot.org/uniprot/I4ADI5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/756499:DESDE_RS16740 ^@ http://purl.uniprot.org/uniprot/I4ACP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS13735 ^@ http://purl.uniprot.org/uniprot/I4AB02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS10485 ^@ http://purl.uniprot.org/uniprot/I4A964 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/756499:DESDE_RS01340 ^@ http://purl.uniprot.org/uniprot/I4A463 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/756499:DESDE_RS05925 ^@ http://purl.uniprot.org/uniprot/I4A6R2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS11860 ^@ http://purl.uniprot.org/uniprot/I4A9Z0 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/756499:DESDE_RS03225 ^@ http://purl.uniprot.org/uniprot/I4A576 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS00305 ^@ http://purl.uniprot.org/uniprot/I4A3M4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/756499:DESDE_RS18155 ^@ http://purl.uniprot.org/uniprot/I4ADH8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS10475 ^@ http://purl.uniprot.org/uniprot/I4A962 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS03255 ^@ http://purl.uniprot.org/uniprot/I4A582 ^@ Similarity ^@ Belongs to the 5'(3')-deoxyribonucleotidase family. http://togogenome.org/gene/756499:DESDE_RS11235 ^@ http://purl.uniprot.org/uniprot/I4A9L8 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/756499:DESDE_RS16605 ^@ http://purl.uniprot.org/uniprot/I4ACM1 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/756499:DESDE_RS04755 ^@ http://purl.uniprot.org/uniprot/I4A625 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS18185 ^@ http://purl.uniprot.org/uniprot/I4ADI4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS00010 ^@ http://purl.uniprot.org/uniprot/I4A3G9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/756499:DESDE_RS04455 ^@ http://purl.uniprot.org/uniprot/I4A5W5 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/756499:DESDE_RS10730 ^@ http://purl.uniprot.org/uniprot/I4A9B4 ^@ Similarity|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.|||Heterodimer of a large and a small subunit. http://togogenome.org/gene/756499:DESDE_RS08385 ^@ http://purl.uniprot.org/uniprot/I4A833 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS16790 ^@ http://purl.uniprot.org/uniprot/I4ACQ9 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/756499:DESDE_RS13905 ^@ http://purl.uniprot.org/uniprot/I4AB37 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/756499:DESDE_RS05655 ^@ http://purl.uniprot.org/uniprot/I4A6K5 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/756499:DESDE_RS20485 ^@ http://purl.uniprot.org/uniprot/I4AET6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS03030 ^@ http://purl.uniprot.org/uniprot/I4A538 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS18920 ^@ http://purl.uniprot.org/uniprot/I4ADX5 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/756499:DESDE_RS16935 ^@ http://purl.uniprot.org/uniprot/I4ACT9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Membrane|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/756499:DESDE_RS17070 ^@ http://purl.uniprot.org/uniprot/I4ACW6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/756499:DESDE_RS00845 ^@ http://purl.uniprot.org/uniprot/I4A3X0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS07800 ^@ http://purl.uniprot.org/uniprot/I4A7S0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/756499:DESDE_RS18505 ^@ http://purl.uniprot.org/uniprot/I4ADP4 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/756499:DESDE_RS17065 ^@ http://purl.uniprot.org/uniprot/I4ACW5 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS18350 ^@ http://purl.uniprot.org/uniprot/I4ADL3 ^@ Similarity|||Subunit ^@ Belongs to the methylaspartate ammonia-lyase family.|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS08905 ^@ http://purl.uniprot.org/uniprot/I4A8D4 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/756499:DESDE_RS14125 ^@ http://purl.uniprot.org/uniprot/I4AB83 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/756499:DESDE_RS11865 ^@ http://purl.uniprot.org/uniprot/I4A9Z1 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M38 family.|||Binds 2 Zn(2+) ions per subunit.|||Carboxylation allows a single lysine to coordinate two zinc ions.|||Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS17710 ^@ http://purl.uniprot.org/uniprot/I4AD89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.|||Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS20225 ^@ http://purl.uniprot.org/uniprot/I4AEN3 ^@ Similarity ^@ Belongs to the RpoE family. http://togogenome.org/gene/756499:DESDE_RS12680 ^@ http://purl.uniprot.org/uniprot/I4AAF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS13590 ^@ http://purl.uniprot.org/uniprot/I4AAX5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS12520 ^@ http://purl.uniprot.org/uniprot/I4AAC5 ^@ Similarity ^@ Belongs to the AAA ATPase family.|||In the C-terminal section; belongs to the peptidase M41 family. http://togogenome.org/gene/756499:DESDE_RS02070 ^@ http://purl.uniprot.org/uniprot/I4A4K6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/756499:DESDE_RS01235 ^@ http://purl.uniprot.org/uniprot/I4A441 ^@ Similarity ^@ Belongs to the GerABKC lipoprotein family. http://togogenome.org/gene/756499:DESDE_RS17715 ^@ http://purl.uniprot.org/uniprot/I4AD90 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS01655 ^@ http://purl.uniprot.org/uniprot/I4A4C5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/756499:DESDE_RS16685 ^@ http://purl.uniprot.org/uniprot/I4ACN8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS01925 ^@ http://purl.uniprot.org/uniprot/I4A4I0 ^@ Similarity ^@ Belongs to the ycf81 family. http://togogenome.org/gene/756499:DESDE_RS15750 ^@ http://purl.uniprot.org/uniprot/I4AC53 ^@ Function|||Similarity ^@ Belongs to the UPF0122 family.|||Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. http://togogenome.org/gene/756499:DESDE_RS00545 ^@ http://purl.uniprot.org/uniprot/I4A3S1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/756499:DESDE_RS00825 ^@ http://purl.uniprot.org/uniprot/I4A3W6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the diaminopimelate dehydrogenase family.|||Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS10110 ^@ http://purl.uniprot.org/uniprot/I4A925 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/756499:DESDE_RS18005 ^@ http://purl.uniprot.org/uniprot/I4ADE8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/756499:DESDE_RS09945 ^@ http://purl.uniprot.org/uniprot/I4A8Z0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/756499:DESDE_RS19160 ^@ http://purl.uniprot.org/uniprot/I4AE23 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/756499:DESDE_RS16060 ^@ http://purl.uniprot.org/uniprot/I4ACB5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/756499:DESDE_RS13820 ^@ http://purl.uniprot.org/uniprot/I4AB20 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell membrane|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/756499:DESDE_RS01600 ^@ http://purl.uniprot.org/uniprot/I4A4B5 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/756499:DESDE_RS05955 ^@ http://purl.uniprot.org/uniprot/I4A6R8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS03015 ^@ http://purl.uniprot.org/uniprot/I4A535 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/756499:DESDE_RS07280 ^@ http://purl.uniprot.org/uniprot/I4A7H2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS10395 ^@ http://purl.uniprot.org/uniprot/I4A945 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/756499:DESDE_RS06210 ^@ http://purl.uniprot.org/uniprot/I4A6X0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/756499:DESDE_RS03450 ^@ http://purl.uniprot.org/uniprot/I4A5C0 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/756499:DESDE_RS01145 ^@ http://purl.uniprot.org/uniprot/I4A427 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/756499:DESDE_RS01380 ^@ http://purl.uniprot.org/uniprot/I4A472 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/756499:DESDE_RS17260 ^@ http://purl.uniprot.org/uniprot/I4AD03 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/756499:DESDE_RS08755 ^@ http://purl.uniprot.org/uniprot/I4A8A4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/756499:DESDE_RS16070 ^@ http://purl.uniprot.org/uniprot/I4ACB7 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/756499:DESDE_RS13690 ^@ http://purl.uniprot.org/uniprot/I4AAZ3 ^@ Function|||Subcellular Location Annotation ^@ ATPase. Has a role at an early stage in the morphogenesis of the spore coat.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS11985 ^@ http://purl.uniprot.org/uniprot/I4AA16 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/756499:DESDE_RS12300 ^@ http://purl.uniprot.org/uniprot/I4AA79 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/756499:DESDE_RS08010 ^@ http://purl.uniprot.org/uniprot/I4A7W2 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. http://togogenome.org/gene/756499:DESDE_RS01265 ^@ http://purl.uniprot.org/uniprot/I4A448 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS17830 ^@ http://purl.uniprot.org/uniprot/I4ADB3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS14450 ^@ http://purl.uniprot.org/uniprot/I4ABE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetokinase family.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS16950 ^@ http://purl.uniprot.org/uniprot/I4ACU2 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/756499:DESDE_RS07345 ^@ http://purl.uniprot.org/uniprot/I4A7I6 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/756499:DESDE_RS11455 ^@ http://purl.uniprot.org/uniprot/I4A9Q6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS10715 ^@ http://purl.uniprot.org/uniprot/I4A9B1 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/756499:DESDE_RS14580 ^@ http://purl.uniprot.org/uniprot/I4ABH2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS16430 ^@ http://purl.uniprot.org/uniprot/I4ACJ1 ^@ Function|||Similarity|||Subunit ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Homodimer and homohexamer; in equilibrium.|||Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. http://togogenome.org/gene/756499:DESDE_RS19445 ^@ http://purl.uniprot.org/uniprot/I4AE79 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS14370 ^@ http://purl.uniprot.org/uniprot/I4ABC9 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/756499:DESDE_RS08680 ^@ http://purl.uniprot.org/uniprot/I4A889 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS11230 ^@ http://purl.uniprot.org/uniprot/I4A9L7 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/756499:DESDE_RS02585 ^@ http://purl.uniprot.org/uniprot/I4A4V3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/756499:DESDE_RS13775 ^@ http://purl.uniprot.org/uniprot/I4AB10 ^@ Function|||Similarity|||Subunit ^@ Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.|||Belongs to the HutP family.|||Homohexamer. http://togogenome.org/gene/756499:DESDE_RS03800 ^@ http://purl.uniprot.org/uniprot/I4A5J2 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/756499:DESDE_RS04730 ^@ http://purl.uniprot.org/uniprot/I4A620 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/756499:DESDE_RS14995 ^@ http://purl.uniprot.org/uniprot/I4ABQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS13980 ^@ http://purl.uniprot.org/uniprot/I4AB52 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family.|||Homotrimer.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/756499:DESDE_RS06665 ^@ http://purl.uniprot.org/uniprot/I4A757 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/756499:DESDE_RS02050 ^@ http://purl.uniprot.org/uniprot/I4A4K2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS16745 ^@ http://purl.uniprot.org/uniprot/I4ACQ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS12080 ^@ http://purl.uniprot.org/uniprot/I4AA34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS18510 ^@ http://purl.uniprot.org/uniprot/I4ADP5 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/756499:DESDE_RS09420 ^@ http://purl.uniprot.org/uniprot/I4A8N4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS01705 ^@ http://purl.uniprot.org/uniprot/I4A4D5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS17765 ^@ http://purl.uniprot.org/uniprot/I4ADA0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/756499:DESDE_RS01735 ^@ http://purl.uniprot.org/uniprot/I4A4E2 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/756499:DESDE_RS08330 ^@ http://purl.uniprot.org/uniprot/I4A823 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/756499:DESDE_RS12125 ^@ http://purl.uniprot.org/uniprot/I4AA43 ^@ Function|||Similarity ^@ 3'-5' exonuclease.|||Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily. http://togogenome.org/gene/756499:DESDE_RS15140 ^@ http://purl.uniprot.org/uniprot/I4ABT1 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/756499:DESDE_RS14435 ^@ http://purl.uniprot.org/uniprot/I4ABE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS09695 ^@ http://purl.uniprot.org/uniprot/I4A8U1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS02230 ^@ http://purl.uniprot.org/uniprot/I4A4N6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS20595 ^@ http://purl.uniprot.org/uniprot/I4AEV6 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/756499:DESDE_RS15935 ^@ http://purl.uniprot.org/uniprot/I4AC90 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS10710 ^@ http://purl.uniprot.org/uniprot/I4A9A9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/756499:DESDE_RS19230 ^@ http://purl.uniprot.org/uniprot/I4AE37 ^@ Cofactor ^@ Binds 4 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/756499:DESDE_RS06395 ^@ http://purl.uniprot.org/uniprot/I4A704 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein S18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS14165 ^@ http://purl.uniprot.org/uniprot/I4AB91 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/756499:DESDE_RS19950 ^@ http://purl.uniprot.org/uniprot/I4AEH8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/756499:DESDE_RS08060 ^@ http://purl.uniprot.org/uniprot/I4A7X2 ^@ Similarity ^@ Belongs to the PHP hydrolase family. HisK subfamily. http://togogenome.org/gene/756499:DESDE_RS12550 ^@ http://purl.uniprot.org/uniprot/I4AAD1 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/756499:DESDE_RS08740 ^@ http://purl.uniprot.org/uniprot/I4A8A1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS11245 ^@ http://purl.uniprot.org/uniprot/I4A9M0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS11275 ^@ http://purl.uniprot.org/uniprot/I4A9M6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/756499:DESDE_RS14520 ^@ http://purl.uniprot.org/uniprot/I4ABF9 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/756499:DESDE_RS14485 ^@ http://purl.uniprot.org/uniprot/I4ABF2 ^@ Similarity ^@ Belongs to the UPF0473 family. http://togogenome.org/gene/756499:DESDE_RS13380 ^@ http://purl.uniprot.org/uniprot/I4AAT5 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/756499:DESDE_RS04920 ^@ http://purl.uniprot.org/uniprot/I4A657 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/756499:DESDE_RS20505 ^@ http://purl.uniprot.org/uniprot/I4AEU0 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/756499:DESDE_RS11430 ^@ http://purl.uniprot.org/uniprot/I4A9Q1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS19070 ^@ http://purl.uniprot.org/uniprot/I4AE05 ^@ Function ^@ Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. http://togogenome.org/gene/756499:DESDE_RS10670 ^@ http://purl.uniprot.org/uniprot/I4A9A1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/756499:DESDE_RS00855 ^@ http://purl.uniprot.org/uniprot/I4A3X2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS04585 ^@ http://purl.uniprot.org/uniprot/I4A5Z1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/756499:DESDE_RS04750 ^@ http://purl.uniprot.org/uniprot/I4A624 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/756499:DESDE_RS02160 ^@ http://purl.uniprot.org/uniprot/I4A4M4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/756499:DESDE_RS01965 ^@ http://purl.uniprot.org/uniprot/I4A4I7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the thymidylate synthase ThyX family.|||Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.|||Homotetramer. http://togogenome.org/gene/756499:DESDE_RS06815 ^@ http://purl.uniprot.org/uniprot/I4A785 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/756499:DESDE_RS14260 ^@ http://purl.uniprot.org/uniprot/I4ABA7 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/756499:DESDE_RS18330 ^@ http://purl.uniprot.org/uniprot/I4ADK9 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/756499:DESDE_RS06640 ^@ http://purl.uniprot.org/uniprot/I4A752 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS06850 ^@ http://purl.uniprot.org/uniprot/I4A792 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS11065 ^@ http://purl.uniprot.org/uniprot/I4A9I2 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/756499:DESDE_RS18865 ^@ http://purl.uniprot.org/uniprot/I4ADW3 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/756499:DESDE_RS01100 ^@ http://purl.uniprot.org/uniprot/I4A418 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS17770 ^@ http://purl.uniprot.org/uniprot/I4ADA1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/756499:DESDE_RS05505 ^@ http://purl.uniprot.org/uniprot/I4A6H8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS06235 ^@ http://purl.uniprot.org/uniprot/I4A6X5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MurCDEF family. MurT subfamily.|||Forms a heterodimer with GatD.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue. http://togogenome.org/gene/756499:DESDE_RS15735 ^@ http://purl.uniprot.org/uniprot/I4AC50 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/756499:DESDE_RS18665 ^@ http://purl.uniprot.org/uniprot/I4ADS4 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/756499:DESDE_RS18755 ^@ http://purl.uniprot.org/uniprot/I4ADU1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS06435 ^@ http://purl.uniprot.org/uniprot/I4A711 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MobA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.|||Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. http://togogenome.org/gene/756499:DESDE_RS12220 ^@ http://purl.uniprot.org/uniprot/I4AA63 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS16970 ^@ http://purl.uniprot.org/uniprot/I4ACU6 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/756499:DESDE_RS15700 ^@ http://purl.uniprot.org/uniprot/I4AC44 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.|||Cytoplasm|||Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. http://togogenome.org/gene/756499:DESDE_RS14915 ^@ http://purl.uniprot.org/uniprot/I4ABN8 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/756499:DESDE_RS06455 ^@ http://purl.uniprot.org/uniprot/I4A715 ^@ Function ^@ May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/756499:DESDE_RS09580 ^@ http://purl.uniprot.org/uniprot/I4A8R7 ^@ Function|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.|||Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB). http://togogenome.org/gene/756499:DESDE_RS16560 ^@ http://purl.uniprot.org/uniprot/I4ACL3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/756499:DESDE_RS13050 ^@ http://purl.uniprot.org/uniprot/I4AAL7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS07580 ^@ http://purl.uniprot.org/uniprot/I4A7M7 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS08230 ^@ http://purl.uniprot.org/uniprot/I4A806 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/756499:DESDE_RS06020 ^@ http://purl.uniprot.org/uniprot/I4A6T0 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/756499:DESDE_RS17110 ^@ http://purl.uniprot.org/uniprot/I4ACX4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/756499:DESDE_RS07730 ^@ http://purl.uniprot.org/uniprot/I4A7Q6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS12545 ^@ http://purl.uniprot.org/uniprot/I4AAD0 ^@ Cofactor|||Similarity ^@ Belongs to the UPF0313 family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/756499:DESDE_RS17555 ^@ http://purl.uniprot.org/uniprot/I4AD59 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/756499:DESDE_RS01355 ^@ http://purl.uniprot.org/uniprot/I4A467 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/756499:DESDE_RS14355 ^@ http://purl.uniprot.org/uniprot/I4ABC6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Cell inner membrane|||Cell membrane|||Membrane|||Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine. http://togogenome.org/gene/756499:DESDE_RS18985 ^@ http://purl.uniprot.org/uniprot/I4ADY8 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/756499:DESDE_RS16205 ^@ http://purl.uniprot.org/uniprot/I4ACE5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/756499:DESDE_RS02005 ^@ http://purl.uniprot.org/uniprot/I4A4J3 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/756499:DESDE_RS12670 ^@ http://purl.uniprot.org/uniprot/I4AAF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS12400 ^@ http://purl.uniprot.org/uniprot/I4AAA1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/756499:DESDE_RS09790 ^@ http://purl.uniprot.org/uniprot/I4A8W0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. http://togogenome.org/gene/756499:DESDE_RS15890 ^@ http://purl.uniprot.org/uniprot/I4AC81 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/756499:DESDE_RS01890 ^@ http://purl.uniprot.org/uniprot/I4A4H3 ^@ Similarity ^@ Belongs to the CtsR family. http://togogenome.org/gene/756499:DESDE_RS12165 ^@ http://purl.uniprot.org/uniprot/I4AA51 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS06415 ^@ http://purl.uniprot.org/uniprot/I4A708 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/756499:DESDE_RS20430 ^@ http://purl.uniprot.org/uniprot/I4AES5 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/756499:DESDE_RS17850 ^@ http://purl.uniprot.org/uniprot/I4ADB7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/756499:DESDE_RS19240 ^@ http://purl.uniprot.org/uniprot/I4AE39 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/756499:DESDE_RS01825 ^@ http://purl.uniprot.org/uniprot/I4A4G0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS16640 ^@ http://purl.uniprot.org/uniprot/I4ACM9 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/756499:DESDE_RS17475 ^@ http://purl.uniprot.org/uniprot/I4AD43 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/756499:DESDE_RS03475 ^@ http://purl.uniprot.org/uniprot/I4A5C6 ^@ Similarity ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family. http://togogenome.org/gene/756499:DESDE_RS14845 ^@ http://purl.uniprot.org/uniprot/I4ABM4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/756499:DESDE_RS14655 ^@ http://purl.uniprot.org/uniprot/I4ABI7 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/756499:DESDE_RS06135 ^@ http://purl.uniprot.org/uniprot/I4A6V4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS12390 ^@ http://purl.uniprot.org/uniprot/I4AA99 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/756499:DESDE_RS13390 ^@ http://purl.uniprot.org/uniprot/I4AAT7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS02115 ^@ http://purl.uniprot.org/uniprot/I4A4L5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/756499:DESDE_RS15660 ^@ http://purl.uniprot.org/uniprot/I4AC36 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/756499:DESDE_RS15470 ^@ http://purl.uniprot.org/uniprot/I4ABZ9 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/756499:DESDE_RS16555 ^@ http://purl.uniprot.org/uniprot/I4ACL2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/756499:DESDE_RS15985 ^@ http://purl.uniprot.org/uniprot/I4ACA0 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/756499:DESDE_RS09620 ^@ http://purl.uniprot.org/uniprot/I4A8S5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS09155 ^@ http://purl.uniprot.org/uniprot/I4A8I2 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/756499:DESDE_RS15770 ^@ http://purl.uniprot.org/uniprot/I4AC57 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.|||Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Homohexamer. Dimer of a homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. http://togogenome.org/gene/756499:DESDE_RS08855 ^@ http://purl.uniprot.org/uniprot/I4A8C4 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/756499:DESDE_RS14365 ^@ http://purl.uniprot.org/uniprot/I4ABC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS13525 ^@ http://purl.uniprot.org/uniprot/I4AAW2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/756499:DESDE_RS09050 ^@ http://purl.uniprot.org/uniprot/I4A8G2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS00590 ^@ http://purl.uniprot.org/uniprot/I4A3S9 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/756499:DESDE_RS17085 ^@ http://purl.uniprot.org/uniprot/I4ACW9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/756499:DESDE_RS16050 ^@ http://purl.uniprot.org/uniprot/I4ACB3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. http://togogenome.org/gene/756499:DESDE_RS04485 ^@ http://purl.uniprot.org/uniprot/I4A5X1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS18760 ^@ http://purl.uniprot.org/uniprot/I4ADU2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS19705 ^@ http://purl.uniprot.org/uniprot/I4AEC8 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/756499:DESDE_RS20570 ^@ http://purl.uniprot.org/uniprot/I4AEV1 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/756499:DESDE_RS04820 ^@ http://purl.uniprot.org/uniprot/I4A637 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/756499:DESDE_RS13340 ^@ http://purl.uniprot.org/uniprot/I4AAS7 ^@ Similarity ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family. http://togogenome.org/gene/756499:DESDE_RS13880 ^@ http://purl.uniprot.org/uniprot/I4AB32 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ScpA family.|||Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.|||Cytoplasm|||Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. http://togogenome.org/gene/756499:DESDE_RS11695 ^@ http://purl.uniprot.org/uniprot/I4A9V5 ^@ Similarity ^@ Belongs to the FtsK/SpoIIIE/SftA family. http://togogenome.org/gene/756499:DESDE_RS02100 ^@ http://purl.uniprot.org/uniprot/I4A4L2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/756499:DESDE_RS00425 ^@ http://purl.uniprot.org/uniprot/I4A3P7 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS00980 ^@ http://purl.uniprot.org/uniprot/I4A3Z7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS04270 ^@ http://purl.uniprot.org/uniprot/I4A5S9 ^@ Similarity ^@ Belongs to the PHP hydrolase family. HisK subfamily. http://togogenome.org/gene/756499:DESDE_RS13780 ^@ http://purl.uniprot.org/uniprot/I4AB11 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell inner membrane|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/756499:DESDE_RS13615 ^@ http://purl.uniprot.org/uniprot/I4AAY0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Forms a complex with TatA.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. http://togogenome.org/gene/756499:DESDE_RS02405 ^@ http://purl.uniprot.org/uniprot/I4A4R7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS16965 ^@ http://purl.uniprot.org/uniprot/I4ACU5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/756499:DESDE_RS09330 ^@ http://purl.uniprot.org/uniprot/I4A8L6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS13065 ^@ http://purl.uniprot.org/uniprot/I4AAM1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20B family.|||Binds 2 Zn(2+) ions per subunit.|||Cleaves the N-terminal amino acid of tripeptides.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS17660 ^@ http://purl.uniprot.org/uniprot/I4AD79 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/756499:DESDE_RS16405 ^@ http://purl.uniprot.org/uniprot/I4ACI6 ^@ Cofactor|||Similarity ^@ Belongs to the PyrK family.|||Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/756499:DESDE_RS14780 ^@ http://purl.uniprot.org/uniprot/I4ABL4 ^@ Similarity ^@ Belongs to the acylphosphatase family.|||Belongs to the carbamoyltransferase HypF family. http://togogenome.org/gene/756499:DESDE_RS08765 ^@ http://purl.uniprot.org/uniprot/I4A8A6 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/756499:DESDE_RS06700 ^@ http://purl.uniprot.org/uniprot/I4A764 ^@ Similarity ^@ Belongs to the manganese catalase family. http://togogenome.org/gene/756499:DESDE_RS19770 ^@ http://purl.uniprot.org/uniprot/I4AEE0 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/756499:DESDE_RS05440 ^@ http://purl.uniprot.org/uniprot/I4A6G6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS18045 ^@ http://purl.uniprot.org/uniprot/I4ADF6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/756499:DESDE_RS15165 ^@ http://purl.uniprot.org/uniprot/I4ABT6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS16925 ^@ http://purl.uniprot.org/uniprot/I4ACT7 ^@ Function|||Similarity ^@ Belongs to the ROK (NagC/XylR) family.|||Transcriptional repressor of xylose-utilizing enzymes. http://togogenome.org/gene/756499:DESDE_RS14250 ^@ http://purl.uniprot.org/uniprot/I4ABA5 ^@ Cofactor ^@ Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/756499:DESDE_RS19795 ^@ http://purl.uniprot.org/uniprot/I4AEE6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/756499:DESDE_RS15365 ^@ http://purl.uniprot.org/uniprot/I4ABX7 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/756499:DESDE_RS16440 ^@ http://purl.uniprot.org/uniprot/I4ACJ3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/756499:DESDE_RS00300 ^@ http://purl.uniprot.org/uniprot/I4A3M3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ribonuclease M5 family.|||Cytoplasm|||Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. http://togogenome.org/gene/756499:DESDE_RS03605 ^@ http://purl.uniprot.org/uniprot/I4A5F2 ^@ Similarity ^@ Belongs to the diacylglycerol/lipid kinase family. http://togogenome.org/gene/756499:DESDE_RS02180 ^@ http://purl.uniprot.org/uniprot/I4A4M8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/756499:DESDE_RS06060 ^@ http://purl.uniprot.org/uniprot/I4A6T8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS09850 ^@ http://purl.uniprot.org/uniprot/I4A8X1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS19835 ^@ http://purl.uniprot.org/uniprot/I4AEF4 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/756499:DESDE_RS06695 ^@ http://purl.uniprot.org/uniprot/I4A763 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/756499:DESDE_RS18390 ^@ http://purl.uniprot.org/uniprot/I4ADM1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS17050 ^@ http://purl.uniprot.org/uniprot/U3GKZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliO/MopB family.|||Cell membrane http://togogenome.org/gene/756499:DESDE_RS13620 ^@ http://purl.uniprot.org/uniprot/I4AAY1 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/756499:DESDE_RS18280 ^@ http://purl.uniprot.org/uniprot/I4ADJ9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/756499:DESDE_RS14120 ^@ http://purl.uniprot.org/uniprot/I4AB82 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/756499:DESDE_RS03135 ^@ http://purl.uniprot.org/uniprot/I4A558 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS14855 ^@ http://purl.uniprot.org/uniprot/I4ABM6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS02190 ^@ http://purl.uniprot.org/uniprot/I4A4M9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/756499:DESDE_RS13100 ^@ http://purl.uniprot.org/uniprot/I4AAM8 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/756499:DESDE_RS10705 ^@ http://purl.uniprot.org/uniprot/I4A9A8 ^@ Similarity ^@ Belongs to the UPF0342 family. http://togogenome.org/gene/756499:DESDE_RS16415 ^@ http://purl.uniprot.org/uniprot/I4ACI8 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/756499:DESDE_RS00985 ^@ http://purl.uniprot.org/uniprot/I4A3Z8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS15040 ^@ http://purl.uniprot.org/uniprot/I4ABR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS00940 ^@ http://purl.uniprot.org/uniprot/I4A3Y9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/756499:DESDE_RS13285 ^@ http://purl.uniprot.org/uniprot/I4AAR6 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/756499:DESDE_RS16975 ^@ http://purl.uniprot.org/uniprot/I4ACU7 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/756499:DESDE_RS02440 ^@ http://purl.uniprot.org/uniprot/I4A4S4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS14575 ^@ http://purl.uniprot.org/uniprot/I4ABH1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS16410 ^@ http://purl.uniprot.org/uniprot/I4ACI7 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS17345 ^@ http://purl.uniprot.org/uniprot/I4AD18 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/756499:DESDE_RS20540 ^@ http://purl.uniprot.org/uniprot/I4AEU6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS03480 ^@ http://purl.uniprot.org/uniprot/I4A5C7 ^@ Similarity ^@ Belongs to the GerABKC lipoprotein family. http://togogenome.org/gene/756499:DESDE_RS20205 ^@ http://purl.uniprot.org/uniprot/I4AEM9 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS15675 ^@ http://purl.uniprot.org/uniprot/I4AC39 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/756499:DESDE_RS03115 ^@ http://purl.uniprot.org/uniprot/I4A554 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS02075 ^@ http://purl.uniprot.org/uniprot/I4A4K7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/756499:DESDE_RS02090 ^@ http://purl.uniprot.org/uniprot/I4A4L0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/756499:DESDE_RS01850 ^@ http://purl.uniprot.org/uniprot/I4A4G5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Cell membrane|||Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS18500 ^@ http://purl.uniprot.org/uniprot/I4ADP3 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/756499:DESDE_RS02300 ^@ http://purl.uniprot.org/uniprot/I4A4Q0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS11585 ^@ http://purl.uniprot.org/uniprot/I4A9T3 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/756499:DESDE_RS00925 ^@ http://purl.uniprot.org/uniprot/I4A3Y7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS03705 ^@ http://purl.uniprot.org/uniprot/I4A5H2 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/756499:DESDE_RS11145 ^@ http://purl.uniprot.org/uniprot/I4A9J9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS10685 ^@ http://purl.uniprot.org/uniprot/I4A9A4 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/756499:DESDE_RS00690 ^@ http://purl.uniprot.org/uniprot/I4A3U3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Cell membrane|||Membrane|||O-acyltransferase that catalyzes D-alanylation of both teichoic acid and lipoteichoic acid (LTA). D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Catalyzes D-alanylation from DltC carrier protein. http://togogenome.org/gene/756499:DESDE_RS18630 ^@ http://purl.uniprot.org/uniprot/I4ADR7 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/756499:DESDE_RS02270 ^@ http://purl.uniprot.org/uniprot/I4A4P4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS00395 ^@ http://purl.uniprot.org/uniprot/I4A3P1 ^@ Function|||Similarity ^@ Belongs to the SpoVG family.|||Could be involved in septation. http://togogenome.org/gene/756499:DESDE_RS06440 ^@ http://purl.uniprot.org/uniprot/I4A712 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/756499:DESDE_RS02195 ^@ http://purl.uniprot.org/uniprot/I4A4N0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/756499:DESDE_RS13885 ^@ http://purl.uniprot.org/uniprot/I4AB33 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/756499:DESDE_RS13595 ^@ http://purl.uniprot.org/uniprot/I4AAX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS20605 ^@ http://purl.uniprot.org/uniprot/I4AEV8 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/756499:DESDE_RS16510 ^@ http://purl.uniprot.org/uniprot/I4ACK5 ^@ Similarity ^@ Belongs to the UPF0236 family. http://togogenome.org/gene/756499:DESDE_RS17870 ^@ http://purl.uniprot.org/uniprot/I4ADC1 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/756499:DESDE_RS04905 ^@ http://purl.uniprot.org/uniprot/I4A654 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/756499:DESDE_RS00180 ^@ http://purl.uniprot.org/uniprot/I4A3J9 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/756499:DESDE_RS06055 ^@ http://purl.uniprot.org/uniprot/I4A6T6 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/756499:DESDE_RS13095 ^@ http://purl.uniprot.org/uniprot/I4AAM7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/756499:DESDE_RS19145 ^@ http://purl.uniprot.org/uniprot/I4AE20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS19530 ^@ http://purl.uniprot.org/uniprot/I4AE96 ^@ Similarity ^@ Belongs to the TelA family. http://togogenome.org/gene/756499:DESDE_RS07615 ^@ http://purl.uniprot.org/uniprot/I4A7N4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS06805 ^@ http://purl.uniprot.org/uniprot/I4A783 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS00315 ^@ http://purl.uniprot.org/uniprot/I4A3M6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS02205 ^@ http://purl.uniprot.org/uniprot/I4A4N2 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/756499:DESDE_RS14445 ^@ http://purl.uniprot.org/uniprot/I4ABE4 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/756499:DESDE_RS09105 ^@ http://purl.uniprot.org/uniprot/I4A8H2 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/756499:DESDE_RS01150 ^@ http://purl.uniprot.org/uniprot/I4A428 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/756499:DESDE_RS00715 ^@ http://purl.uniprot.org/uniprot/I4A3U9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS00015 ^@ http://purl.uniprot.org/uniprot/I4A3H0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/756499:DESDE_RS17630 ^@ http://purl.uniprot.org/uniprot/I4AD74 ^@ Cofactor ^@ Binds 4 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/756499:DESDE_RS12265 ^@ http://purl.uniprot.org/uniprot/I4AA71 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/756499:DESDE_RS16730 ^@ http://purl.uniprot.org/uniprot/I4ACP7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS06960 ^@ http://purl.uniprot.org/uniprot/I4A7B4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS02235 ^@ http://purl.uniprot.org/uniprot/I4A4N7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS11025 ^@ http://purl.uniprot.org/uniprot/I4A9H4 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/756499:DESDE_RS10280 ^@ http://purl.uniprot.org/uniprot/I4A929 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS12875 ^@ http://purl.uniprot.org/uniprot/I4AAI3 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/756499:DESDE_RS19960 ^@ http://purl.uniprot.org/uniprot/I4AEI0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/756499:DESDE_RS14600 ^@ http://purl.uniprot.org/uniprot/I4ABH7 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS09715 ^@ http://purl.uniprot.org/uniprot/I4A8U6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS05315 ^@ http://purl.uniprot.org/uniprot/I4A6D8 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/756499:DESDE_RS13875 ^@ http://purl.uniprot.org/uniprot/I4AB31 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ScpB family.|||Cytoplasm|||Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.|||Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. http://togogenome.org/gene/756499:DESDE_RS18945 ^@ http://purl.uniprot.org/uniprot/I4ADY0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS01210 ^@ http://purl.uniprot.org/uniprot/I4A436 ^@ Similarity ^@ Belongs to the UPF0246 family. http://togogenome.org/gene/756499:DESDE_RS16210 ^@ http://purl.uniprot.org/uniprot/I4ACE6 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS05840 ^@ http://purl.uniprot.org/uniprot/I4A6P5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS06705 ^@ http://purl.uniprot.org/uniprot/I4A765 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS14020 ^@ http://purl.uniprot.org/uniprot/I4AB60 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/756499:DESDE_RS19580 ^@ http://purl.uniprot.org/uniprot/I4AEA6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/756499:DESDE_RS03950 ^@ http://purl.uniprot.org/uniprot/I4A5M0 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/756499:DESDE_RS17320 ^@ http://purl.uniprot.org/uniprot/I4AD16 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/756499:DESDE_RS16820 ^@ http://purl.uniprot.org/uniprot/I4ACR6 ^@ Similarity ^@ Belongs to the UPF0342 family. http://togogenome.org/gene/756499:DESDE_RS00390 ^@ http://purl.uniprot.org/uniprot/I4A3P0 ^@ Similarity ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/756499:DESDE_RS09300 ^@ http://purl.uniprot.org/uniprot/I4A8L0 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/756499:DESDE_RS17045 ^@ http://purl.uniprot.org/uniprot/U3GKI2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/756499:DESDE_RS18400 ^@ http://purl.uniprot.org/uniprot/I4ADM3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS06800 ^@ http://purl.uniprot.org/uniprot/I4A782 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/756499:DESDE_RS09315 ^@ http://purl.uniprot.org/uniprot/I4A8L3 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/756499:DESDE_RS09435 ^@ http://purl.uniprot.org/uniprot/I4A8N8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS19980 ^@ http://purl.uniprot.org/uniprot/I4AEI4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/756499:DESDE_RS08665 ^@ http://purl.uniprot.org/uniprot/I4A886 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/756499:DESDE_RS12850 ^@ http://purl.uniprot.org/uniprot/I4AAH8 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/756499:DESDE_RS02640 ^@ http://purl.uniprot.org/uniprot/I4A4W4 ^@ Similarity ^@ Belongs to the Vsr family. http://togogenome.org/gene/756499:DESDE_RS20265 ^@ http://purl.uniprot.org/uniprot/I4AEP2 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/756499:DESDE_RS08785 ^@ http://purl.uniprot.org/uniprot/I4A8B0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS20470 ^@ http://purl.uniprot.org/uniprot/I4AET3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/756499:DESDE_RS11460 ^@ http://purl.uniprot.org/uniprot/I4A9Q7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS00415 ^@ http://purl.uniprot.org/uniprot/I4A3P5 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/756499:DESDE_RS17540 ^@ http://purl.uniprot.org/uniprot/I4AD56 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/756499:DESDE_RS00905 ^@ http://purl.uniprot.org/uniprot/I4A3Y3 ^@ Subcellular Location Annotation ^@ Periplasm http://togogenome.org/gene/756499:DESDE_RS09750 ^@ http://purl.uniprot.org/uniprot/I4A8V3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS16885 ^@ http://purl.uniprot.org/uniprot/I4ACS9 ^@ Similarity ^@ Belongs to the MecA family. http://togogenome.org/gene/756499:DESDE_RS02985 ^@ http://purl.uniprot.org/uniprot/I4A529 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/756499:DESDE_RS00405 ^@ http://purl.uniprot.org/uniprot/I4A3P3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/756499:DESDE_RS05170 ^@ http://purl.uniprot.org/uniprot/I4A6B0 ^@ Function|||Similarity ^@ Belongs to the RecD family. RecD-like subfamily.|||DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity. http://togogenome.org/gene/756499:DESDE_RS14475 ^@ http://purl.uniprot.org/uniprot/I4ABF0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/756499:DESDE_RS17470 ^@ http://purl.uniprot.org/uniprot/I4AD42 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/756499:DESDE_RS16480 ^@ http://purl.uniprot.org/uniprot/I4ACK1 ^@ Function|||Similarity ^@ Belongs to the PduL family.|||Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. http://togogenome.org/gene/756499:DESDE_RS20315 ^@ http://purl.uniprot.org/uniprot/I4AEQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS14030 ^@ http://purl.uniprot.org/uniprot/I4AB63 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/756499:DESDE_RS02000 ^@ http://purl.uniprot.org/uniprot/I4A4J2 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/756499:DESDE_RS18695 ^@ http://purl.uniprot.org/uniprot/I4ADT0 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/756499:DESDE_RS05055 ^@ http://purl.uniprot.org/uniprot/I4A684 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/756499:DESDE_RS02715 ^@ http://purl.uniprot.org/uniprot/I4A4Y0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS15995 ^@ http://purl.uniprot.org/uniprot/I4ACA2 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HSP33 family.|||Cytoplasm|||Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.|||Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive. http://togogenome.org/gene/756499:DESDE_RS14905 ^@ http://purl.uniprot.org/uniprot/I4ABN6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/756499:DESDE_RS06505 ^@ http://purl.uniprot.org/uniprot/I4A725 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/756499:DESDE_RS10895 ^@ http://purl.uniprot.org/uniprot/I4A9E9 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/756499:DESDE_RS14175 ^@ http://purl.uniprot.org/uniprot/I4AB93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS10530 ^@ http://purl.uniprot.org/uniprot/I4A973 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell membrane|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/756499:DESDE_RS04460 ^@ http://purl.uniprot.org/uniprot/I4A5W6 ^@ Caution|||Function ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS07700 ^@ http://purl.uniprot.org/uniprot/I4A7Q0 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/756499:DESDE_RS02170 ^@ http://purl.uniprot.org/uniprot/I4A4M6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/756499:DESDE_RS03610 ^@ http://purl.uniprot.org/uniprot/I4A5F3 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/756499:DESDE_RS10665 ^@ http://purl.uniprot.org/uniprot/I4A9A0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/756499:DESDE_RS07885 ^@ http://purl.uniprot.org/uniprot/I4A7T7 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/756499:DESDE_RS17315 ^@ http://purl.uniprot.org/uniprot/I4AD14 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/756499:DESDE_RS13640 ^@ http://purl.uniprot.org/uniprot/I4AAY5 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/756499:DESDE_RS15710 ^@ http://purl.uniprot.org/uniprot/I4AC46 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/756499:DESDE_RS09730 ^@ http://purl.uniprot.org/uniprot/I4A8U9 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/756499:DESDE_RS16045 ^@ http://purl.uniprot.org/uniprot/I4ACB2 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/756499:DESDE_RS02955 ^@ http://purl.uniprot.org/uniprot/I4A522 ^@ Function|||Similarity|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/756499:DESDE_RS02110 ^@ http://purl.uniprot.org/uniprot/I4A4L4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/756499:DESDE_RS05890 ^@ http://purl.uniprot.org/uniprot/I4A6Q5 ^@ Function ^@ Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. http://togogenome.org/gene/756499:DESDE_RS17480 ^@ http://purl.uniprot.org/uniprot/I4AD44 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/756499:DESDE_RS17115 ^@ http://purl.uniprot.org/uniprot/I4ACX5 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/756499:DESDE_RS06315 ^@ http://purl.uniprot.org/uniprot/I4A6Y9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS15105 ^@ http://purl.uniprot.org/uniprot/I4ABS4 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/756499:DESDE_RS07205 ^@ http://purl.uniprot.org/uniprot/I4A7F8 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS18215 ^@ http://purl.uniprot.org/uniprot/I4ADJ0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/756499:DESDE_RS06250 ^@ http://purl.uniprot.org/uniprot/I4A6X8 ^@ Function|||Similarity ^@ Belongs to the PemK/MazF family.|||Toxic component of a type II toxin-antitoxin (TA) system. http://togogenome.org/gene/756499:DESDE_RS01720 ^@ http://purl.uniprot.org/uniprot/I4A4D9 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/756499:DESDE_RS03120 ^@ http://purl.uniprot.org/uniprot/I4A555 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/756499:DESDE_RS19200 ^@ http://purl.uniprot.org/uniprot/I4AE31 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/756499:DESDE_RS08850 ^@ http://purl.uniprot.org/uniprot/I4A8C3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS18625 ^@ http://purl.uniprot.org/uniprot/I4ADR6 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/756499:DESDE_RS02885 ^@ http://purl.uniprot.org/uniprot/I4A508 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/756499:DESDE_RS17560 ^@ http://purl.uniprot.org/uniprot/I4AD60 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/756499:DESDE_RS18930 ^@ http://purl.uniprot.org/uniprot/I4ADX7 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/756499:DESDE_RS14770 ^@ http://purl.uniprot.org/uniprot/I4ABL2 ^@ Similarity ^@ Belongs to the HypD family. http://togogenome.org/gene/756499:DESDE_RS00355 ^@ http://purl.uniprot.org/uniprot/I4A3N4 ^@ Function|||Similarity ^@ Belongs to the peptidase S51 family.|||Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides. http://togogenome.org/gene/756499:DESDE_RS01005 ^@ http://purl.uniprot.org/uniprot/I4A402 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS04665 ^@ http://purl.uniprot.org/uniprot/I4A607 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/756499:DESDE_RS04660 ^@ http://purl.uniprot.org/uniprot/I4A606 ^@ Similarity ^@ Belongs to the MEMO1 family. http://togogenome.org/gene/756499:DESDE_RS08565 ^@ http://purl.uniprot.org/uniprot/I4A866 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS06660 ^@ http://purl.uniprot.org/uniprot/I4A756 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/756499:DESDE_RS12895 ^@ http://purl.uniprot.org/uniprot/I4AAI7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/756499:DESDE_RS08015 ^@ http://purl.uniprot.org/uniprot/I4A7W3 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the peroxidase family. Peroxidase/catalase subfamily.|||Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.|||Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS07860 ^@ http://purl.uniprot.org/uniprot/I4A7T2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/756499:DESDE_RS19600 ^@ http://purl.uniprot.org/uniprot/I4AEA9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/756499:DESDE_RS17800 ^@ http://purl.uniprot.org/uniprot/I4ADA7 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS18285 ^@ http://purl.uniprot.org/uniprot/I4ADK0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/756499:DESDE_RS12100 ^@ http://purl.uniprot.org/uniprot/I4AA38 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/756499:DESDE_RS18980 ^@ http://purl.uniprot.org/uniprot/I4ADY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS05490 ^@ http://purl.uniprot.org/uniprot/I4A6H5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS13555 ^@ http://purl.uniprot.org/uniprot/I4AAW8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ALAD family.|||Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.|||Homooctamer. http://togogenome.org/gene/756499:DESDE_RS00755 ^@ http://purl.uniprot.org/uniprot/I4A3V9 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/756499:DESDE_RS18055 ^@ http://purl.uniprot.org/uniprot/I4ADF8 ^@ Function|||Similarity ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily. http://togogenome.org/gene/756499:DESDE_RS07040 ^@ http://purl.uniprot.org/uniprot/I4A7C6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS10775 ^@ http://purl.uniprot.org/uniprot/I4A9C4 ^@ Similarity ^@ Belongs to the pyruvate kinase family.|||In the C-terminal section; belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/756499:DESDE_RS07185 ^@ http://purl.uniprot.org/uniprot/I4A7F4 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/756499:DESDE_RS11350 ^@ http://purl.uniprot.org/uniprot/I4A9N7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/756499:DESDE_RS17785 ^@ http://purl.uniprot.org/uniprot/I4ADA4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/756499:DESDE_RS08920 ^@ http://purl.uniprot.org/uniprot/I4A8D7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS05685 ^@ http://purl.uniprot.org/uniprot/I4A6L2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS14170 ^@ http://purl.uniprot.org/uniprot/I4AB92 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/756499:DESDE_RS20460 ^@ http://purl.uniprot.org/uniprot/I4AET1 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/756499:DESDE_RS04865 ^@ http://purl.uniprot.org/uniprot/I4A646 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/756499:DESDE_RS14425 ^@ http://purl.uniprot.org/uniprot/I4ABE0 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase. http://togogenome.org/gene/756499:DESDE_RS11870 ^@ http://purl.uniprot.org/uniprot/I4A9Z2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS19095 ^@ http://purl.uniprot.org/uniprot/I4AE10 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/756499:DESDE_RS00695 ^@ http://purl.uniprot.org/uniprot/I4A3U4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.|||Belongs to the DltC family.|||Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS20565 ^@ http://purl.uniprot.org/uniprot/I4AEV0 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/756499:DESDE_RS09800 ^@ http://purl.uniprot.org/uniprot/I4A8W2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/756499:DESDE_RS01955 ^@ http://purl.uniprot.org/uniprot/I4A4I5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/756499:DESDE_RS10555 ^@ http://purl.uniprot.org/uniprot/I4A978 ^@ Similarity ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. http://togogenome.org/gene/756499:DESDE_RS02915 ^@ http://purl.uniprot.org/uniprot/I4A514 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/756499:DESDE_RS14135 ^@ http://purl.uniprot.org/uniprot/I4AB85 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS02130 ^@ http://purl.uniprot.org/uniprot/I4A4L8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/756499:DESDE_RS06385 ^@ http://purl.uniprot.org/uniprot/I4A702 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS14025 ^@ http://purl.uniprot.org/uniprot/I4AB61 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/756499:DESDE_RS19720 ^@ http://purl.uniprot.org/uniprot/I4AED1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/756499:DESDE_RS10900 ^@ http://purl.uniprot.org/uniprot/I4A9F0 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/756499:DESDE_RS05645 ^@ http://purl.uniprot.org/uniprot/I4A6K3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS15960 ^@ http://purl.uniprot.org/uniprot/I4AC95 ^@ Function|||Similarity ^@ Belongs to the alpha/beta-type SASP family.|||SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. http://togogenome.org/gene/756499:DESDE_RS17670 ^@ http://purl.uniprot.org/uniprot/I4AD81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS02990 ^@ http://purl.uniprot.org/uniprot/I4A530 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/756499:DESDE_RS20195 ^@ http://purl.uniprot.org/uniprot/I4AEM7 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/756499:DESDE_RS00485 ^@ http://purl.uniprot.org/uniprot/I4A3Q9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/756499:DESDE_RS18595 ^@ http://purl.uniprot.org/uniprot/I4ADR0 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS19605 ^@ http://purl.uniprot.org/uniprot/I4AEB0 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/756499:DESDE_RS04800 ^@ http://purl.uniprot.org/uniprot/I4A633 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/756499:DESDE_RS03945 ^@ http://purl.uniprot.org/uniprot/I4A5L9 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/756499:DESDE_RS01015 ^@ http://purl.uniprot.org/uniprot/I4A404 ^@ Similarity ^@ Belongs to the phosphopentomutase family. http://togogenome.org/gene/756499:DESDE_RS19035 ^@ http://purl.uniprot.org/uniprot/I4ADZ8 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/756499:DESDE_RS03130 ^@ http://purl.uniprot.org/uniprot/I4A557 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/756499:DESDE_RS13835 ^@ http://purl.uniprot.org/uniprot/I4AB23 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/756499:DESDE_RS14930 ^@ http://purl.uniprot.org/uniprot/I4ABP1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/756499:DESDE_RS16425 ^@ http://purl.uniprot.org/uniprot/I4ACJ0 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/756499:DESDE_RS02210 ^@ http://purl.uniprot.org/uniprot/I4A4N3 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/756499:DESDE_RS02580 ^@ http://purl.uniprot.org/uniprot/I4A4V2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/756499:DESDE_RS12785 ^@ http://purl.uniprot.org/uniprot/I4AAG9 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/756499:DESDE_RS15055 ^@ http://purl.uniprot.org/uniprot/I4ABR4 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS06975 ^@ http://purl.uniprot.org/uniprot/I4A7B7 ^@ Similarity ^@ Belongs to the NifH/BchL/ChlL family. http://togogenome.org/gene/756499:DESDE_RS13135 ^@ http://purl.uniprot.org/uniprot/I4AAN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS16545 ^@ http://purl.uniprot.org/uniprot/I4ACL0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. C-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/756499:DESDE_RS00795 ^@ http://purl.uniprot.org/uniprot/I4A3W0 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-I family. http://togogenome.org/gene/756499:DESDE_RS11885 ^@ http://purl.uniprot.org/uniprot/I4A9Z5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/756499:DESDE_RS15045 ^@ http://purl.uniprot.org/uniprot/I4ABR2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS19320 ^@ http://purl.uniprot.org/uniprot/I4AE53 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/756499:DESDE_RS03395 ^@ http://purl.uniprot.org/uniprot/I4A5A8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the adenylate cyclase family. DacA/CdaA subfamily.|||Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably a homodimer. http://togogenome.org/gene/756499:DESDE_RS18130 ^@ http://purl.uniprot.org/uniprot/I4ADH3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/756499:DESDE_RS14935 ^@ http://purl.uniprot.org/uniprot/I4ABP2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/756499:DESDE_RS02255 ^@ http://purl.uniprot.org/uniprot/I4A4P1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS07465 ^@ http://purl.uniprot.org/uniprot/I4A7K5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the AB hydrolase superfamily. MenH family.|||Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).|||Monomer. http://togogenome.org/gene/756499:DESDE_RS06735 ^@ http://purl.uniprot.org/uniprot/I4A771 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.|||This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one. http://togogenome.org/gene/756499:DESDE_RS10090 ^@ http://purl.uniprot.org/uniprot/I4A920 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS19935 ^@ http://purl.uniprot.org/uniprot/I4AEH5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS14075 ^@ http://purl.uniprot.org/uniprot/I4AB72 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/756499:DESDE_RS13750 ^@ http://purl.uniprot.org/uniprot/I4AB05 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell membrane|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/756499:DESDE_RS11370 ^@ http://purl.uniprot.org/uniprot/I4AAG9 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/756499:DESDE_RS06675 ^@ http://purl.uniprot.org/uniprot/I4A759 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/756499:DESDE_RS14110 ^@ http://purl.uniprot.org/uniprot/I4AB80 ^@ Cofactor|||Function|||Subcellular Location Annotation ^@ Binds 1 Ca(2+) ion per subunit.|||Cytoplasm|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS12840 ^@ http://purl.uniprot.org/uniprot/I4AAH7 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS19250 ^@ http://purl.uniprot.org/uniprot/I4AE41 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/756499:DESDE_RS15885 ^@ http://purl.uniprot.org/uniprot/I4AC80 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS05915 ^@ http://purl.uniprot.org/uniprot/I4A6R0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/756499:DESDE_RS04740 ^@ http://purl.uniprot.org/uniprot/I4A622 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS16265 ^@ http://purl.uniprot.org/uniprot/I4ACF6 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/756499:DESDE_RS16635 ^@ http://purl.uniprot.org/uniprot/I4ACM8 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/756499:DESDE_RS02505 ^@ http://purl.uniprot.org/uniprot/I4A4T7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/756499:DESDE_RS14550 ^@ http://purl.uniprot.org/uniprot/I4ABG6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/756499:DESDE_RS19595 ^@ http://purl.uniprot.org/uniprot/I4AEA8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/756499:DESDE_RS16660 ^@ http://purl.uniprot.org/uniprot/I4ACN3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS02065 ^@ http://purl.uniprot.org/uniprot/I4A4K5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/756499:DESDE_RS03625 ^@ http://purl.uniprot.org/uniprot/I4A5F6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS15110 ^@ http://purl.uniprot.org/uniprot/I4ABS5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic Ku family.|||Homodimer. Interacts with LigD.|||With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. http://togogenome.org/gene/756499:DESDE_RS08885 ^@ http://purl.uniprot.org/uniprot/I4A8D0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/756499:DESDE_RS18680 ^@ http://purl.uniprot.org/uniprot/I4ADS7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS17170 ^@ http://purl.uniprot.org/uniprot/I4ACY5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS03665 ^@ http://purl.uniprot.org/uniprot/I4A5G4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS00105 ^@ http://purl.uniprot.org/uniprot/I4A3I5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS13755 ^@ http://purl.uniprot.org/uniprot/I4AB06 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/756499:DESDE_RS11030 ^@ http://purl.uniprot.org/uniprot/I4A9H5 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/756499:DESDE_RS08835 ^@ http://purl.uniprot.org/uniprot/I4A8C0 ^@ Similarity ^@ Belongs to the GerABKA family. http://togogenome.org/gene/756499:DESDE_RS11955 ^@ http://purl.uniprot.org/uniprot/I4AA10 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS10630 ^@ http://purl.uniprot.org/uniprot/I4A993 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/756499:DESDE_RS15975 ^@ http://purl.uniprot.org/uniprot/I4AC98 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/756499:DESDE_RS17925 ^@ http://purl.uniprot.org/uniprot/I4ADD2 ^@ Similarity ^@ Belongs to the methylamine corrinoid protein family. http://togogenome.org/gene/756499:DESDE_RS15160 ^@ http://purl.uniprot.org/uniprot/I4ABT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EamA transporter family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS10880 ^@ http://purl.uniprot.org/uniprot/I4A9E6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0182 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS10700 ^@ http://purl.uniprot.org/uniprot/I4A9A7 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/756499:DESDE_RS13990 ^@ http://purl.uniprot.org/uniprot/I4AB54 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/756499:DESDE_RS15350 ^@ http://purl.uniprot.org/uniprot/I4ABX4 ^@ Similarity ^@ Belongs to the intimin/invasin family. http://togogenome.org/gene/756499:DESDE_RS20635 ^@ http://purl.uniprot.org/uniprot/I4AEW4 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/756499:DESDE_RS13975 ^@ http://purl.uniprot.org/uniprot/I4AB51 ^@ Function|||Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS19625 ^@ http://purl.uniprot.org/uniprot/I4AEB4 ^@ Function|||Similarity ^@ Belongs to the RapZ-like family.|||Displays ATPase and GTPase activities. http://togogenome.org/gene/756499:DESDE_RS17615 ^@ http://purl.uniprot.org/uniprot/I4AD71 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SelA family.|||Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS18085 ^@ http://purl.uniprot.org/uniprot/I4ADG4 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/756499:DESDE_RS19165 ^@ http://purl.uniprot.org/uniprot/I4AE24 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/756499:DESDE_RS04875 ^@ http://purl.uniprot.org/uniprot/I4A648 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/756499:DESDE_RS16770 ^@ http://purl.uniprot.org/uniprot/I4ACQ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/756499:DESDE_RS19610 ^@ http://purl.uniprot.org/uniprot/I4AEB1 ^@ Similarity ^@ Belongs to the sigma-54 factor family. http://togogenome.org/gene/756499:DESDE_RS16065 ^@ http://purl.uniprot.org/uniprot/I4ACB6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/756499:DESDE_RS18210 ^@ http://purl.uniprot.org/uniprot/I4ADI9 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/756499:DESDE_RS11240 ^@ http://purl.uniprot.org/uniprot/I4A9L9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetyl-CoA hydrolase/transferase family.|||Coenzyme A-transferase that converts butyrate to butyryl-CoA.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS15095 ^@ http://purl.uniprot.org/uniprot/I4ABS2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmG family. TrmFO subfamily.|||Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS04955 ^@ http://purl.uniprot.org/uniprot/I4A664 ^@ Similarity ^@ Belongs to the UPF0237 family. http://togogenome.org/gene/756499:DESDE_RS15815 ^@ http://purl.uniprot.org/uniprot/I4AC66 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/756499:DESDE_RS09630 ^@ http://purl.uniprot.org/uniprot/I4A8S7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/756499:DESDE_RS19820 ^@ http://purl.uniprot.org/uniprot/I4AEF1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS08265 ^@ http://purl.uniprot.org/uniprot/I4A813 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/756499:DESDE_RS01240 ^@ http://purl.uniprot.org/uniprot/I4A442 ^@ Similarity ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family. http://togogenome.org/gene/756499:DESDE_RS09520 ^@ http://purl.uniprot.org/uniprot/I4A8Q5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/756499:DESDE_RS15670 ^@ http://purl.uniprot.org/uniprot/I4AC38 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/756499:DESDE_RS16985 ^@ http://purl.uniprot.org/uniprot/I4ACU9 ^@ Function|||Similarity ^@ Belongs to the FliK family.|||Controls the length of the flagellar hook. http://togogenome.org/gene/756499:DESDE_RS19765 ^@ http://purl.uniprot.org/uniprot/I4AED9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS09385 ^@ http://purl.uniprot.org/uniprot/I4A8M6 ^@ Similarity ^@ Belongs to the UPF0173 family. http://togogenome.org/gene/756499:DESDE_RS17020 ^@ http://purl.uniprot.org/uniprot/U3GKZ1 ^@ Function|||Similarity ^@ Belongs to the GTP-binding SRP family.|||Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. http://togogenome.org/gene/756499:DESDE_RS15755 ^@ http://purl.uniprot.org/uniprot/I4AC54 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS14010 ^@ http://purl.uniprot.org/uniprot/I4AB58 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/756499:DESDE_RS02175 ^@ http://purl.uniprot.org/uniprot/I4A4M7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/756499:DESDE_RS09005 ^@ http://purl.uniprot.org/uniprot/I4A8F4 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/756499:DESDE_RS15610 ^@ http://purl.uniprot.org/uniprot/I4AC26 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS09415 ^@ http://purl.uniprot.org/uniprot/I4A8N3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS19045 ^@ http://purl.uniprot.org/uniprot/I4AE00 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.|||Homodimer.|||Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate. http://togogenome.org/gene/756499:DESDE_RS00560 ^@ http://purl.uniprot.org/uniprot/I4A3S4 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/756499:DESDE_RS20130 ^@ http://purl.uniprot.org/uniprot/I4AEL4 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/756499:DESDE_RS15725 ^@ http://purl.uniprot.org/uniprot/I4AC49 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/756499:DESDE_RS01990 ^@ http://purl.uniprot.org/uniprot/I4A4J0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/756499:DESDE_RS09625 ^@ http://purl.uniprot.org/uniprot/I4A8S6 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/756499:DESDE_RS17820 ^@ http://purl.uniprot.org/uniprot/I4ADB1 ^@ Cofactor|||Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Binds 1 FAD per subunit.|||Binds 1 FMN covalently per subunit. http://togogenome.org/gene/756499:DESDE_RS03105 ^@ http://purl.uniprot.org/uniprot/I4A552 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ThrE exporter (TC 2.A.79) family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS07475 ^@ http://purl.uniprot.org/uniprot/I4A7K7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS04345 ^@ http://purl.uniprot.org/uniprot/I4A5U3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS09635 ^@ http://purl.uniprot.org/uniprot/I4A8S8 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/756499:DESDE_RS10450 ^@ http://purl.uniprot.org/uniprot/I4A956 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters.|||Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. http://togogenome.org/gene/756499:DESDE_RS10035 ^@ http://purl.uniprot.org/uniprot/I4A908 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/756499:DESDE_RS07050 ^@ http://purl.uniprot.org/uniprot/I4A7C8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/756499:DESDE_RS06410 ^@ http://purl.uniprot.org/uniprot/I4A707 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/756499:DESDE_RS19485 ^@ http://purl.uniprot.org/uniprot/I4AE87 ^@ Similarity ^@ Belongs to the terpene synthase family. http://togogenome.org/gene/756499:DESDE_RS10570 ^@ http://purl.uniprot.org/uniprot/I4A981 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/756499:DESDE_RS21320 ^@ http://purl.uniprot.org/uniprot/I4AC87 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/756499:DESDE_RS03440 ^@ http://purl.uniprot.org/uniprot/I4A5B8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.|||Membrane http://togogenome.org/gene/756499:DESDE_RS00320 ^@ http://purl.uniprot.org/uniprot/I4A3M7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS17895 ^@ http://purl.uniprot.org/uniprot/I4ADC6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS03085 ^@ http://purl.uniprot.org/uniprot/I4A549 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/756499:DESDE_RS19615 ^@ http://purl.uniprot.org/uniprot/I4AEB2 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/756499:DESDE_RS13420 ^@ http://purl.uniprot.org/uniprot/I4AAU4 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/756499:DESDE_RS08760 ^@ http://purl.uniprot.org/uniprot/I4A8A5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/756499:DESDE_RS06110 ^@ http://purl.uniprot.org/uniprot/I4A6U9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/756499:DESDE_RS12535 ^@ http://purl.uniprot.org/uniprot/I4AAC8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.|||Cytoplasm http://togogenome.org/gene/756499:DESDE_RS03930 ^@ http://purl.uniprot.org/uniprot/I4A5L6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/756499:DESDE_RS15065 ^@ http://purl.uniprot.org/uniprot/I4ABR6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/756499:DESDE_RS03415 ^@ http://purl.uniprot.org/uniprot/I4A5B2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/756499:DESDE_RS02975 ^@ http://purl.uniprot.org/uniprot/I4A527 ^@ Function|||Similarity|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/756499:DESDE_RS04775 ^@ http://purl.uniprot.org/uniprot/I4A628 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/756499:DESDE_RS18830 ^@ http://purl.uniprot.org/uniprot/I4ADV7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/756499:DESDE_RS14140 ^@ http://purl.uniprot.org/uniprot/I4AB86 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/756499:DESDE_RS00190 ^@ http://purl.uniprot.org/uniprot/I4A3K1 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/756499:DESDE_RS20335 ^@ http://purl.uniprot.org/uniprot/I4AEQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS06025 ^@ http://purl.uniprot.org/uniprot/I4A6T1 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. http://togogenome.org/gene/756499:DESDE_RS18165 ^@ http://purl.uniprot.org/uniprot/I4ADI0 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/756499:DESDE_RS06150 ^@ http://purl.uniprot.org/uniprot/I4A6V7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/756499:DESDE_RS17235 ^@ http://purl.uniprot.org/uniprot/I4ACZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted