http://togogenome.org/gene/74969:fad_RS00825 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1T8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/74969:fad_RS05730 ^@ http://purl.uniprot.org/uniprot/A0A1V0N4H6 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/74969:fad_RS05175 ^@ http://purl.uniprot.org/uniprot/A0A1V0N494 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|||Cytoplasm http://togogenome.org/gene/74969:fad_RS07890 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5Q1 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/74969:fad_RS07190 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5C7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/74969:fad_RS03090 ^@ http://purl.uniprot.org/uniprot/A0A1V0N320 ^@ Subcellular Location Annotation ^@ Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/74969:fad_RS02495 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2U7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.|||Cytoplasm|||Involved in both the arginine and lysine biosynthetic pathways.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/74969:fad_RS08395 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5Y5 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. Prx6 subfamily.|||Cytoplasm|||Homodecamer. Pentamer of dimers that assemble into a ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/74969:fad_RS03780 ^@ http://purl.uniprot.org/uniprot/A0A7K4FNC5 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/74969:fad_RS00990 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1V1 ^@ Function|||Similarity ^@ Belongs to the eIF-1A family.|||Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. http://togogenome.org/gene/74969:fad_RS00240 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1L9 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/74969:fad_RS02250 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2J2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/74969:fad_RS02940 ^@ http://purl.uniprot.org/uniprot/A0A1V0N337 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/74969:fad_RS00160 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1F4 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/74969:fad_RS08160 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5W0 ^@ Function|||Similarity ^@ Belongs to the NOP10 family.|||Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. http://togogenome.org/gene/74969:fad_RS02005 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2K0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic/archaeal RNase P protein component 4 family.|||Binds 1 zinc ion per subunit.|||Consists of a catalytic RNA component and at least 4-5 protein subunits.|||Cytoplasm|||Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. http://togogenome.org/gene/74969:fad_RS01105 ^@ http://purl.uniprot.org/uniprot/A0A1V0N235 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/74969:fad_RS05760 ^@ http://purl.uniprot.org/uniprot/A0A7K4FPN8 ^@ Caution|||Similarity ^@ Belongs to the SAICAR synthetase family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/74969:fad_RS00650 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1R6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer. http://togogenome.org/gene/74969:fad_RS03150 ^@ http://purl.uniprot.org/uniprot/A0A1V0N378 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/74969:fad_RS08340 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5Z2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the activator 1 small subunits family. RfcS subfamily.|||Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).|||Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA. http://togogenome.org/gene/74969:fad_RS07455 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5K4 ^@ Similarity ^@ Belongs to the arsA ATPase family. http://togogenome.org/gene/74969:fad_RS00260 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1H5 ^@ Caution|||Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnD subfamily.|||Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/74969:fad_RS01275 ^@ http://purl.uniprot.org/uniprot/A0A1V0N202 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/74969:fad_RS03860 ^@ http://purl.uniprot.org/uniprot/A0A1V0N3N0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SEC61-beta family.|||Cell membrane|||Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.|||Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.|||Membrane http://togogenome.org/gene/74969:fad_RS07900 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5T9 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/74969:fad_RS01225 ^@ http://purl.uniprot.org/uniprot/A0A7K4FKM3 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/74969:fad_RS01965 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2I7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the prefoldin alpha subunit family.|||Belongs to the prefoldin subunit alpha family.|||Cytoplasm|||Heterohexamer of two alpha and four beta subunits.|||Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. http://togogenome.org/gene/74969:fad_RS01185 ^@ http://purl.uniprot.org/uniprot/A0A1V0N230 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. http://togogenome.org/gene/74969:fad_RS00830 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1W0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges. http://togogenome.org/gene/74969:fad_RS07460 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5H4 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/74969:fad_RS07445 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5I4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TYW1 family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).|||Cytoplasm|||Monomer. http://togogenome.org/gene/74969:fad_RS08090 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5R6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/74969:fad_RS00220 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1F2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL21 family. http://togogenome.org/gene/74969:fad_RS07980 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5U6 ^@ Similarity ^@ Belongs to the ComB family. http://togogenome.org/gene/74969:fad_RS01180 ^@ http://purl.uniprot.org/uniprot/A0A1V0N248 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/74969:fad_RS01400 ^@ http://purl.uniprot.org/uniprot/A0A1V0N276 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/74969:fad_RS00630 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1R2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the archaeal DnaG primase family.|||Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. http://togogenome.org/gene/74969:fad_RS07860 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5Q3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/74969:fad_RS08895 ^@ http://purl.uniprot.org/uniprot/A0A1V0N689 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic release factor 1 family.|||Cytoplasm|||Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.|||Heterodimer of two subunits, one of which binds GTP. http://togogenome.org/gene/74969:fad_RS07910 ^@ http://purl.uniprot.org/uniprot/A0A7K4FKI2 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/74969:fad_RS08940 ^@ http://purl.uniprot.org/uniprot/A0A1V0N6B3 ^@ Function|||Similarity ^@ Belongs to the type-2 OGG1 family.|||Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA. Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites). http://togogenome.org/gene/74969:fad_RS01580 ^@ http://purl.uniprot.org/uniprot/A0A1V0N289 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/74969:fad_RS02145 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2H3 ^@ Similarity|||Subunit ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family.|||Homohexamer. http://togogenome.org/gene/74969:fad_RS00935 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1U6 ^@ Similarity ^@ Belongs to the snRNP Sm proteins family. http://togogenome.org/gene/74969:fad_RS07640 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5H9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/74969:fad_RS00810 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1W3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/74969:fad_RS02120 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2M2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS1 family. http://togogenome.org/gene/74969:fad_RS07290 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5E8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/74969:fad_RS00675 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1Q5 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. http://togogenome.org/gene/74969:fad_RS02075 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2I0 ^@ Function|||Similarity ^@ Belongs to the TFIIB family.|||Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). http://togogenome.org/gene/74969:fad_RS08665 ^@ http://purl.uniprot.org/uniprot/A0A1V0N681 ^@ Similarity ^@ Belongs to the BCKDHA family. http://togogenome.org/gene/74969:fad_RS02560 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2Q8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpA family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/74969:fad_RS01705 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2D8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/74969:fad_RS01710 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2A6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/74969:fad_RS02815 ^@ http://purl.uniprot.org/uniprot/A0A1V0N312 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/74969:fad_RS08145 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5S5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL42 family.|||Binds 1 zinc ion per subunit.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/74969:fad_RS07865 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5N0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/74969:fad_RS02375 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2R8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL15 family. http://togogenome.org/gene/74969:fad_RS07040 ^@ http://purl.uniprot.org/uniprot/A0A1V0N571 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/74969:fad_RS05330 ^@ http://purl.uniprot.org/uniprot/A0A1V0N4A8 ^@ Similarity ^@ Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. http://togogenome.org/gene/74969:fad_RS02955 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2Y2 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/74969:fad_RS06720 ^@ http://purl.uniprot.org/uniprot/A0A1V0N514 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the prefoldin subunit beta family.|||Cytoplasm|||Heterohexamer of two alpha and four beta subunits.|||Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. http://togogenome.org/gene/74969:fad_RS00655 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1U2 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/74969:fad_RS00785 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1R3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29. http://togogenome.org/gene/74969:fad_RS00855 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1Y9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/74969:fad_RS02130 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2J0 ^@ Similarity ^@ Belongs to the ice-binding protein family. http://togogenome.org/gene/74969:fad_RS07960 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5S3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion. http://togogenome.org/gene/74969:fad_RS00780 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1V0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/74969:fad_RS08020 ^@ http://purl.uniprot.org/uniprot/A0A7K4FKX8 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/74969:fad_RS00880 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1X0 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Part of the 30S ribosomal subunit. Contacts protein S4.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/74969:fad_RS08620 ^@ http://purl.uniprot.org/uniprot/A0A1V0N679 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the archaeosine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/74969:fad_RS08885 ^@ http://purl.uniprot.org/uniprot/A0A1V0N660 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/74969:fad_RS05850 ^@ http://purl.uniprot.org/uniprot/A0A7K4FNS5 ^@ Caution|||Similarity|||Subunit ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.|||Heterooligomer of catalytic and regulatory chains.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/74969:fad_RS00845 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1S5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/74969:fad_RS00865 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1Y8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL32 family. http://togogenome.org/gene/74969:fad_RS07225 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5F0 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/74969:fad_RS06375 ^@ http://purl.uniprot.org/uniprot/A0A7K4FLH4 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/74969:fad_RS08990 ^@ http://purl.uniprot.org/uniprot/A0A1V0N6C1 ^@ Similarity ^@ Belongs to the V-ATPase F subunit family. http://togogenome.org/gene/74969:fad_RS01405 ^@ http://purl.uniprot.org/uniprot/A0A1V0N247 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Part of the 30S ribosomal subunit.|||With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. http://togogenome.org/gene/74969:fad_RS01735 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2B9 ^@ Similarity ^@ Belongs to the CGI121/TPRKB family. http://togogenome.org/gene/74969:fad_RS01640 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2C9 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/74969:fad_RS08050 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5W9 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/74969:fad_RS02620 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2W4 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/74969:fad_RS08695 ^@ http://purl.uniprot.org/uniprot/A0A7K4FPX8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/74969:fad_RS06425 ^@ http://purl.uniprot.org/uniprot/A0A1V0N503 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/74969:fad_RS02150 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2N6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PCNA family.|||Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.|||Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. http://togogenome.org/gene/74969:fad_RS08015 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5R1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the methylthiotransferase family. CDKAL1 subfamily.|||Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/74969:fad_RS05640 ^@ http://purl.uniprot.org/uniprot/A0A1V0N4F4 ^@ Similarity ^@ Belongs to the MoaD family. http://togogenome.org/gene/74969:fad_RS00790 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1X6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL2 family. http://togogenome.org/gene/74969:fad_RS01620 ^@ http://purl.uniprot.org/uniprot/A0A7K4FMW9 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/74969:fad_RS05780 ^@ http://purl.uniprot.org/uniprot/A0A1V0N4L3 ^@ Cofactor|||Similarity ^@ Belongs to the ELP3 family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/74969:fad_RS00245 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1L1 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. UPF0219 family. http://togogenome.org/gene/74969:fad_RS07680 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5L4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/74969:fad_RS07270 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5D6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/74969:fad_RS02820 ^@ http://purl.uniprot.org/uniprot/A0A1V0N339 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Homodimer.|||Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). http://togogenome.org/gene/74969:fad_RS01510 ^@ http://purl.uniprot.org/uniprot/A0A7K4FPT2 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/74969:fad_RS01095 ^@ http://purl.uniprot.org/uniprot/A0A1V0N217 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eIF-5A family.|||Cytoplasm|||Functions by promoting the formation of the first peptide bond. http://togogenome.org/gene/74969:fad_RS01720 ^@ http://purl.uniprot.org/uniprot/A0A1V0N290 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/74969:fad_RS08005 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5P4 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the ferredoxin--NADP reductase type 2 family.|||Binds 1 FAD per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/74969:fad_RS01660 ^@ http://purl.uniprot.org/uniprot/A0A1V0N296 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/74969:fad_RS01010 ^@ http://purl.uniprot.org/uniprot/A0A1V0N212 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds at least 2 Zn(2+) per subunit.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/74969:fad_RS08920 ^@ http://purl.uniprot.org/uniprot/A0A7K4FNC8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/74969:fad_RS00205 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1J9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.|||Binds 1 zinc ion per subunit.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/74969:fad_RS01415 ^@ http://purl.uniprot.org/uniprot/A0A1V0N231 ^@ Similarity ^@ Belongs to the UPF0179 family. http://togogenome.org/gene/74969:fad_RS00800 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1U1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/74969:fad_RS08935 ^@ http://purl.uniprot.org/uniprot/A0A1V0N666 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/74969:fad_RS05635 ^@ http://purl.uniprot.org/uniprot/A0A1V0N4K3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/74969:fad_RS02555 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2V7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/74969:fad_RS01150 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1Y1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STT3 family.|||Membrane http://togogenome.org/gene/74969:fad_RS01000 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1V5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NusA family.|||Cytoplasm|||Participates in transcription termination. http://togogenome.org/gene/74969:fad_RS06745 ^@ http://purl.uniprot.org/uniprot/A0A1V0N528 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/74969:fad_RS01290 ^@ http://purl.uniprot.org/uniprot/A0A1V0N261 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the RNA polymerase complex. http://togogenome.org/gene/74969:fad_RS01635 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2D3 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the FBP aldolase/phosphatase family.|||Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).|||Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.|||Homooctamer; dimer of tetramers. http://togogenome.org/gene/74969:fad_RS08785 ^@ http://purl.uniprot.org/uniprot/A0A1V0N642 ^@ Caution|||Function|||Similarity ^@ Belongs to the TBP family.|||General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/74969:fad_RS02840 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2V2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. Hel308 subfamily.|||DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.|||Monomer. http://togogenome.org/gene/74969:fad_RS00870 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1X4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL19 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/74969:fad_RS07510 ^@ http://purl.uniprot.org/uniprot/A0A7K4FR71 ^@ Caution|||Similarity ^@ Belongs to the TCP-1 chaperonin family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/74969:fad_RS06905 ^@ http://purl.uniprot.org/uniprot/A0A1V0N562 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/74969:fad_RS00075 ^@ http://purl.uniprot.org/uniprot/A0A7K4FN21 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/74969:fad_RS07465 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5F3 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.|||Belongs to the histone-like Alba family.|||Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.|||Chromosome|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/74969:fad_RS00915 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1Z9 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.|||Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/74969:fad_RS03095 ^@ http://purl.uniprot.org/uniprot/A0A1V0N361 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/74969:fad_RS02325 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2Q7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal NMN adenylyltransferase family.|||Cytoplasm http://togogenome.org/gene/74969:fad_RS02630 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2Z7 ^@ Function|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family. http://togogenome.org/gene/74969:fad_RS07985 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5V4 ^@ Function|||Similarity ^@ Belongs to the archaeal 6-HMPDK family.|||Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP). http://togogenome.org/gene/74969:fad_RS03045 ^@ http://purl.uniprot.org/uniprot/A0A1V0N352 ^@ Similarity ^@ Belongs to the complex I subunit 3 family. http://togogenome.org/gene/74969:fad_RS09020 ^@ http://purl.uniprot.org/uniprot/A0A1V0N6C2 ^@ Similarity ^@ Belongs to the ZPR1 family. http://togogenome.org/gene/74969:fad_RS02020 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2H0 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/74969:fad_RS00875 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1U7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/74969:fad_RS02900 ^@ http://purl.uniprot.org/uniprot/A0A1V0N327 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS28 family. http://togogenome.org/gene/74969:fad_RS02910 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2X7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NDK family.|||Cytoplasm|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/74969:fad_RS05420 ^@ http://purl.uniprot.org/uniprot/A0A1V0N4G1 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/74969:fad_RS08670 ^@ http://purl.uniprot.org/uniprot/A0A7K4FPK4 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/74969:fad_RS03050 ^@ http://purl.uniprot.org/uniprot/A0A7K4FM49 ^@ Caution|||Similarity ^@ Belongs to the complex I 20 kDa subunit family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/74969:fad_RS01730 ^@ http://purl.uniprot.org/uniprot/A0A1V0N291 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively.|||Belongs to the peptidase S16 family. Archaeal LonB subfamily.|||Cell membrane|||Homohexamer. Organized in a ring with a central cavity.|||Membrane http://togogenome.org/gene/74969:fad_RS05825 ^@ http://purl.uniprot.org/uniprot/A0A1V0N4M7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eIF-2-beta/eIF-5 family.|||Heterotrimer composed of an alpha, a beta and a gamma chain.|||eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. http://togogenome.org/gene/74969:fad_RS07255 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5B8 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.|||The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/74969:fad_RS06705 ^@ http://purl.uniprot.org/uniprot/A0A1V0N547 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Homohexamer. Dimer of a homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/74969:fad_RS01265 ^@ http://purl.uniprot.org/uniprot/A0A1V0N200 ^@ Similarity ^@ Belongs to the MCM family. http://togogenome.org/gene/74969:fad_RS07315 ^@ http://purl.uniprot.org/uniprot/A0A7K4FL88 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/74969:fad_RS07895 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5M4 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/74969:fad_RS09105 ^@ http://purl.uniprot.org/uniprot/A0A1V0N6D8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NAC-alpha family.|||Contacts the emerging nascent chain on the ribosome.|||Homodimer. Interacts with the ribosome. Binds ribosomal RNA. http://togogenome.org/gene/74969:fad_RS07555 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM19 family.|||Membrane http://togogenome.org/gene/74969:fad_RS09005 ^@ http://purl.uniprot.org/uniprot/A0A1V0N6D7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Membrane http://togogenome.org/gene/74969:fad_RS07695 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5I8 ^@ Similarity ^@ Belongs to the eukaryotic/archaeal PrmC-related family. http://togogenome.org/gene/74969:fad_RS01450 ^@ http://purl.uniprot.org/uniprot/A0A1V0N287 ^@ Cofactor|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/74969:fad_RS08110 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5T1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/74969:fad_RS00985 ^@ http://purl.uniprot.org/uniprot/A0A7K4FMW1 ^@ Caution|||Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/74969:fad_RS02270 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2P8 ^@ Function|||Similarity ^@ Belongs to the GTP-dependent DPCK family.|||Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). http://togogenome.org/gene/74969:fad_RS02435 ^@ http://purl.uniprot.org/uniprot/Q2PCE2 ^@ Function|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.|||Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB). http://togogenome.org/gene/74969:fad_RS09180 ^@ http://purl.uniprot.org/uniprot/A0A1V0N6I2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/74969:fad_RS01845 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2G5 ^@ Similarity ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. http://togogenome.org/gene/74969:fad_RS02925 ^@ http://purl.uniprot.org/uniprot/A0A1V0N360 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/74969:fad_RS00370 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1L0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL39 family. http://togogenome.org/gene/74969:fad_RS09160 ^@ http://purl.uniprot.org/uniprot/A0A1V0N6D5 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. Prx6 subfamily.|||Cytoplasm|||Homodecamer. Pentamer of dimers that assemble into a ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/74969:fad_RS02315 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2L8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/74969:fad_RS00885 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1T9 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/74969:fad_RS02415 ^@ http://purl.uniprot.org/uniprot/A0A7K4FRY4 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/74969:fad_RS07925 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5S6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/74969:fad_RS07020 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5A8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the archaeal dihydroneopterin aldolase family.|||Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).|||Homotetramer. http://togogenome.org/gene/74969:fad_RS08115 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5T8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/74969:fad_RS00805 ^@ http://purl.uniprot.org/uniprot/A0A7K4FKU2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head.|||Part of the 30S ribosomal subunit.|||The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/74969:fad_RS02545 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2V9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/74969:fad_RS07855 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5L1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.|||Binds 1 zinc ion.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/74969:fad_RS02870 ^@ http://purl.uniprot.org/uniprot/A0A1V0N348 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/74969:fad_RS00200 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1K7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase PH family. Rrp42 subfamily.|||Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.|||Cytoplasm|||Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. http://togogenome.org/gene/74969:fad_RS00210 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1G1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.|||Binds 1 zinc ion.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/74969:fad_RS06810 ^@ http://purl.uniprot.org/uniprot/A0A1V0N573 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/74969:fad_RS09060 ^@ http://purl.uniprot.org/uniprot/A0A1V0N6B4 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/74969:fad_RS08625 ^@ http://purl.uniprot.org/uniprot/A0A1V0N641 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/74969:fad_RS07235 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5G1 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/74969:fad_RS00670 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1T4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS6 family. http://togogenome.org/gene/74969:fad_RS07100 ^@ http://purl.uniprot.org/uniprot/A0A1V0N577 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS17 family. http://togogenome.org/gene/74969:fad_RS05805 ^@ http://purl.uniprot.org/uniprot/A0A1V0N4L8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/74969:fad_RS07700 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5M6 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the SMC family. RAD50 subfamily.|||Binds 1 zinc ion per homodimer.|||Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.|||The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer. http://togogenome.org/gene/74969:fad_RS09025 ^@ http://purl.uniprot.org/uniprot/A0A1V0N685 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IPP isomerase type 2 family.|||Cytoplasm|||Homooctamer. Dimer of tetramers.|||Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/74969:fad_RS00665 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1U4 ^@ Similarity ^@ Belongs to the HAM1 NTPase family. http://togogenome.org/gene/74969:fad_RS07970 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5Q8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. Probably involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.|||Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA. http://togogenome.org/gene/74969:fad_RS02525 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2V0 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/74969:fad_RS02030 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2F6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/74969:fad_RS06050 ^@ http://purl.uniprot.org/uniprot/A0A1V0N4N6 ^@ Similarity ^@ Belongs to the transcriptional regulator TrmB family. http://togogenome.org/gene/74969:fad_RS08010 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5T2 ^@ Function|||Similarity ^@ Belongs to the DPH1/DPH2 family.|||Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). http://togogenome.org/gene/74969:fad_RS00905 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1Z5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/74969:fad_RS02035 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2L7 ^@ Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS8 family.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/74969:fad_RS07610 ^@ http://purl.uniprot.org/uniprot/A0A7K4FNF0 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/74969:fad_RS08750 ^@ http://purl.uniprot.org/uniprot/A0A1V0N653 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/74969:fad_RS01325 ^@ http://purl.uniprot.org/uniprot/A0A1V0N216 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/74969:fad_RS02260 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2J5 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS31 family.|||Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/74969:fad_RS02065 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2M6 ^@ Function|||Similarity ^@ Belongs to the TFIIB family.|||Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). http://togogenome.org/gene/74969:fad_RS00840 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1Y4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS4 family. http://togogenome.org/gene/74969:fad_RS03085 ^@ http://purl.uniprot.org/uniprot/A0A1V0N377 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/74969:fad_RS00360 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1M4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS19 family.|||May be involved in maturation of the 30S ribosomal subunit.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/74969:fad_RS00090 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1I7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). http://togogenome.org/gene/74969:fad_RS02275 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2P7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the archaeal Spt4 family.|||Heterodimer composed of Spt4 and Spt5.|||Stimulates transcription elongation. http://togogenome.org/gene/74969:fad_RS00365 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1J5 ^@ Similarity ^@ Belongs to the PDCD5 family. http://togogenome.org/gene/74969:fad_RS08890 ^@ http://purl.uniprot.org/uniprot/A0A1V0N6A1 ^@ Similarity ^@ Belongs to the UMP kinase family. http://togogenome.org/gene/74969:fad_RS02710 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2T6 ^@ Function|||Similarity ^@ Belongs to the eukaryotic RecA-like protein family.|||Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. http://togogenome.org/gene/74969:fad_RS05430 ^@ http://purl.uniprot.org/uniprot/A0A1V0N4E5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/74969:fad_RS00900 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1W2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal adenylate kinase family.|||Cytoplasm http://togogenome.org/gene/74969:fad_RS00795 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1R1 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/74969:fad_RS00660 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1T3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. BUD32 family. http://togogenome.org/gene/74969:fad_RS03065 ^@ http://purl.uniprot.org/uniprot/A0A1V0N308 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/74969:fad_RS02745 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2T3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.|||Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.|||Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.|||Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA. http://togogenome.org/gene/74969:fad_RS03030 ^@ http://purl.uniprot.org/uniprot/A0A1V0N379 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/74969:fad_RS01145 ^@ http://purl.uniprot.org/uniprot/A0A1V0N227 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/74969:fad_RS09140 ^@ http://purl.uniprot.org/uniprot/A0A1V0N6A9 ^@ Cofactor|||Function ^@ Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 zinc ion.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/74969:fad_RS03100 ^@ http://purl.uniprot.org/uniprot/A0A1V0N303 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/74969:fad_RS03965 ^@ http://purl.uniprot.org/uniprot/A0A1V0N3Q4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/74969:fad_RS06865 ^@ http://purl.uniprot.org/uniprot/A0A1V0N582 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Cytoplasm http://togogenome.org/gene/74969:fad_RS05620 ^@ http://purl.uniprot.org/uniprot/A0A1V0N4I9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/74969:fad_RS01525 ^@ http://purl.uniprot.org/uniprot/A0A1V0N253 ^@ Cofactor|||Similarity ^@ Belongs to the PdaD family.|||Binds 1 pyruvoyl group covalently per subunit. http://togogenome.org/gene/74969:fad_RS01420 ^@ http://purl.uniprot.org/uniprot/A0A1V0N293 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycerol-1-phosphate dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.|||Cytoplasm http://togogenome.org/gene/74969:fad_RS07975 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5T6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/74969:fad_RS02280 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2S2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.|||Nucleus|||Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure. http://togogenome.org/gene/74969:fad_RS05410 ^@ http://purl.uniprot.org/uniprot/A0A1V0N4E3 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/74969:fad_RS01195 ^@ http://purl.uniprot.org/uniprot/A0A1V0N236 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/74969:fad_RS01610 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2B4 ^@ Function|||Similarity ^@ Belongs to the CDC6/cdc18 family.|||Involved in regulation of DNA replication. http://togogenome.org/gene/74969:fad_RS07965 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5Q0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion. http://togogenome.org/gene/74969:fad_RS04170 ^@ http://purl.uniprot.org/uniprot/A0A1V0N3T8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/74969:fad_RS02160 ^@ http://purl.uniprot.org/uniprot/A0A1V0N2H8 ^@ Similarity ^@ Belongs to the adenosylhomocysteinase family. http://togogenome.org/gene/74969:fad_RS07795 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5R9 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.|||The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/74969:fad_RS07015 ^@ http://purl.uniprot.org/uniprot/A0A1V0N575 ^@ Caution|||Function|||Similarity ^@ Belongs to the THEP1 NTPase family.|||Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/74969:fad_RS07920 ^@ http://purl.uniprot.org/uniprot/A0A1V0N5P8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.|||Cytoplasm http://togogenome.org/gene/74969:fad_RS00775 ^@ http://purl.uniprot.org/uniprot/A0A1V0N1S8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL3 family.