http://togogenome.org/gene/747365:THENA_RS02720 ^@ http://purl.uniprot.org/uniprot/M1E7X1 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/747365:THENA_RS08260 ^@ http://purl.uniprot.org/uniprot/M1E8K9 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/747365:THENA_RS05095 ^@ http://purl.uniprot.org/uniprot/M1E8R3 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS02385 ^@ http://purl.uniprot.org/uniprot/M1E4F8 ^@ Similarity|||Subunit ^@ Belongs to the FBP aldolase/phosphatase family.|||Homooctamer; dimer of tetramers. http://togogenome.org/gene/747365:THENA_RS03240 ^@ http://purl.uniprot.org/uniprot/M1E719 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS00490 ^@ http://purl.uniprot.org/uniprot/M1E5J2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS08940 ^@ http://purl.uniprot.org/uniprot/M1E610 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/747365:THENA_RS03745 ^@ http://purl.uniprot.org/uniprot/M1E4P5 ^@ Similarity ^@ Belongs to the pyruvoyl-dependent arginine decarboxylase family. http://togogenome.org/gene/747365:THENA_RS01270 ^@ http://purl.uniprot.org/uniprot/M1E7A8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 130 family. http://togogenome.org/gene/747365:THENA_RS08820 ^@ http://purl.uniprot.org/uniprot/M1E8T4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/747365:THENA_RS04145 ^@ http://purl.uniprot.org/uniprot/M1E8F3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/747365:THENA_RS08555 ^@ http://purl.uniprot.org/uniprot/M1E8Q0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/747365:THENA_RS06745 ^@ http://purl.uniprot.org/uniprot/M1E838 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/747365:THENA_RS02995 ^@ http://purl.uniprot.org/uniprot/M1E5F2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/747365:THENA_RS04935 ^@ http://purl.uniprot.org/uniprot/M1E4V9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmG family. TrmFO subfamily.|||Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS01990 ^@ http://purl.uniprot.org/uniprot/M1E7K6 ^@ Similarity ^@ Belongs to the HepT RNase toxin family. http://togogenome.org/gene/747365:THENA_RS02810 ^@ http://purl.uniprot.org/uniprot/M1E7X7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/747365:THENA_RS08850 ^@ http://purl.uniprot.org/uniprot/M1E9I5 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated Csm2 family.|||This subunit may be involved in monitoring complementarity of crRNA and target RNA. http://togogenome.org/gene/747365:THENA_RS04600 ^@ http://purl.uniprot.org/uniprot/M1E8K7 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/747365:THENA_RS01185 ^@ http://purl.uniprot.org/uniprot/M1E5X5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Forms a complex with TatA.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. http://togogenome.org/gene/747365:THENA_RS02990 ^@ http://purl.uniprot.org/uniprot/M1E6X7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/747365:THENA_RS02770 ^@ http://purl.uniprot.org/uniprot/M1E4I5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/747365:THENA_RS03405 ^@ http://purl.uniprot.org/uniprot/M1E744 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/747365:THENA_RS04020 ^@ http://purl.uniprot.org/uniprot/M1E7E1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS09245 ^@ http://purl.uniprot.org/uniprot/M1E9K1 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/747365:THENA_RS05555 ^@ http://purl.uniprot.org/uniprot/M1E6B2 ^@ Similarity ^@ Belongs to the HypD family. http://togogenome.org/gene/747365:THENA_RS07585 ^@ http://purl.uniprot.org/uniprot/M1E723 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS03095 ^@ http://purl.uniprot.org/uniprot/M1E5G3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/747365:THENA_RS08855 ^@ http://purl.uniprot.org/uniprot/M1E953 ^@ Similarity ^@ Belongs to the CRISPR-associated Cas10/Csm1 family. http://togogenome.org/gene/747365:THENA_RS05735 ^@ http://purl.uniprot.org/uniprot/M1E516 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS00325 ^@ http://purl.uniprot.org/uniprot/M1E4R0 ^@ Similarity|||Subunit ^@ Belongs to the KdsC family.|||Homotetramer. http://togogenome.org/gene/747365:THENA_RS04125 ^@ http://purl.uniprot.org/uniprot/M1E5R5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/747365:THENA_RS03880 ^@ http://purl.uniprot.org/uniprot/M1E4Q2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/747365:THENA_RS04730 ^@ http://purl.uniprot.org/uniprot/M1E799 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/747365:THENA_RS06365 ^@ http://purl.uniprot.org/uniprot/M1E948 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS09215 ^@ http://purl.uniprot.org/uniprot/M1E8W6 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/747365:THENA_RS02815 ^@ http://purl.uniprot.org/uniprot/M1E6U7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/747365:THENA_RS07590 ^@ http://purl.uniprot.org/uniprot/M1E5H4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/747365:THENA_RS05145 ^@ http://purl.uniprot.org/uniprot/M1E8R8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS08270 ^@ http://purl.uniprot.org/uniprot/M1E8Z1 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/747365:THENA_RS01540 ^@ http://purl.uniprot.org/uniprot/M1E4B5 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/747365:THENA_RS00320 ^@ http://purl.uniprot.org/uniprot/M1E5Q9 ^@ Similarity ^@ Belongs to the SIS family. GutQ/KpsF subfamily. http://togogenome.org/gene/747365:THENA_RS05085 ^@ http://purl.uniprot.org/uniprot/M1E4W8 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/747365:THENA_RS07960 ^@ http://purl.uniprot.org/uniprot/M1E9F1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS04950 ^@ http://purl.uniprot.org/uniprot/M1E7S6 ^@ Function|||Similarity ^@ Belongs to the HMBS family.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. http://togogenome.org/gene/747365:THENA_RS03360 ^@ http://purl.uniprot.org/uniprot/M1E5J1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS06205 ^@ http://purl.uniprot.org/uniprot/M1E935 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/747365:THENA_RS03125 ^@ http://purl.uniprot.org/uniprot/M1E4K7 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/747365:THENA_RS04290 ^@ http://purl.uniprot.org/uniprot/M1E7L3 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/747365:THENA_RS03165 ^@ http://purl.uniprot.org/uniprot/M1E705 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/747365:THENA_RS01110 ^@ http://purl.uniprot.org/uniprot/M1E787 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/747365:THENA_RS08885 ^@ http://purl.uniprot.org/uniprot/M1E7P9 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS08345 ^@ http://purl.uniprot.org/uniprot/M1E7E6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LPG synthase family.|||Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS05440 ^@ http://purl.uniprot.org/uniprot/M1E7Z6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.|||Membrane http://togogenome.org/gene/747365:THENA_RS09230 ^@ http://purl.uniprot.org/uniprot/M1E7U0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/747365:THENA_RS03410 ^@ http://purl.uniprot.org/uniprot/M1E5J9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/747365:THENA_RS03460 ^@ http://purl.uniprot.org/uniprot/M1E5L1 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/747365:THENA_RS01145 ^@ http://purl.uniprot.org/uniprot/M1E4Z6 ^@ Function|||Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/747365:THENA_RS03355 ^@ http://purl.uniprot.org/uniprot/M1E736 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS09565 ^@ http://purl.uniprot.org/uniprot/M1E564 ^@ Similarity ^@ Belongs to the phosphoribulokinase family. http://togogenome.org/gene/747365:THENA_RS06305 ^@ http://purl.uniprot.org/uniprot/M1E943 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/747365:THENA_RS07545 ^@ http://purl.uniprot.org/uniprot/M1E5G9 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/747365:THENA_RS09730 ^@ http://purl.uniprot.org/uniprot/M1E8I8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS02680 ^@ http://purl.uniprot.org/uniprot/M1E5B8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL17 family. http://togogenome.org/gene/747365:THENA_RS01050 ^@ http://purl.uniprot.org/uniprot/M1E5W2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/747365:THENA_RS05105 ^@ http://purl.uniprot.org/uniprot/M1E643 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/747365:THENA_RS06830 ^@ http://purl.uniprot.org/uniprot/M1E8H7 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/747365:THENA_RS00155 ^@ http://purl.uniprot.org/uniprot/M1E429 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/747365:THENA_RS00070 ^@ http://purl.uniprot.org/uniprot/M1E423 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/747365:THENA_RS01250 ^@ http://purl.uniprot.org/uniprot/M1E6A9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/747365:THENA_RS03640 ^@ http://purl.uniprot.org/uniprot/M1E4P0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/747365:THENA_RS09710 ^@ http://purl.uniprot.org/uniprot/M1E8J3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL21 family.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/747365:THENA_RS05910 ^@ http://purl.uniprot.org/uniprot/M1E911 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/747365:THENA_RS00510 ^@ http://purl.uniprot.org/uniprot/M1E466 ^@ Similarity ^@ Belongs to the peptidase C59 family. http://togogenome.org/gene/747365:THENA_RS03655 ^@ http://purl.uniprot.org/uniprot/M1E790 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/747365:THENA_RS06960 ^@ http://purl.uniprot.org/uniprot/M1E8J0 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/747365:THENA_RS09080 ^@ http://purl.uniprot.org/uniprot/M1E970 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/747365:THENA_RS06940 ^@ http://purl.uniprot.org/uniprot/M1E6T6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS06750 ^@ http://purl.uniprot.org/uniprot/M1E980 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS05080 ^@ http://purl.uniprot.org/uniprot/M1E640 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/747365:THENA_RS00890 ^@ http://purl.uniprot.org/uniprot/M1E665 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/747365:THENA_RS06090 ^@ http://purl.uniprot.org/uniprot/M1E549 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/747365:THENA_RS05115 ^@ http://purl.uniprot.org/uniprot/M1E7G2 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/747365:THENA_RS03960 ^@ http://purl.uniprot.org/uniprot/M1E707 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/747365:THENA_RS06770 ^@ http://purl.uniprot.org/uniprot/M1E839 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/747365:THENA_RS06395 ^@ http://purl.uniprot.org/uniprot/M1E8C9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS07955 ^@ http://purl.uniprot.org/uniprot/M1E8H2 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/747365:THENA_RS03260 ^@ http://purl.uniprot.org/uniprot/M1E855 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/747365:THENA_RS05035 ^@ http://purl.uniprot.org/uniprot/M1E4W5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS04595 ^@ http://purl.uniprot.org/uniprot/M1E781 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/747365:THENA_RS00355 ^@ http://purl.uniprot.org/uniprot/M1E453 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS02690 ^@ http://purl.uniprot.org/uniprot/M1E6H4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/747365:THENA_RS01000 ^@ http://purl.uniprot.org/uniprot/M1E493 ^@ Similarity ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily. http://togogenome.org/gene/747365:THENA_RS06425 ^@ http://purl.uniprot.org/uniprot/M1E6M7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/747365:THENA_RS04485 ^@ http://purl.uniprot.org/uniprot/M1E8J2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS09390 ^@ http://purl.uniprot.org/uniprot/M1E7W2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS03170 ^@ http://purl.uniprot.org/uniprot/M1E5H1 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/747365:THENA_RS07995 ^@ http://purl.uniprot.org/uniprot/M1E784 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/747365:THENA_RS06965 ^@ http://purl.uniprot.org/uniprot/M1E6T9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS08955 ^@ http://purl.uniprot.org/uniprot/M1E961 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/747365:THENA_RS02545 ^@ http://purl.uniprot.org/uniprot/M1E7U1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/747365:THENA_RS04960 ^@ http://purl.uniprot.org/uniprot/M1E4W0 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/747365:THENA_RS01175 ^@ http://purl.uniprot.org/uniprot/M1E4Z7 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. LacC subfamily.|||Belongs to the carbohydrate kinase pfkB family. http://togogenome.org/gene/747365:THENA_RS03340 ^@ http://purl.uniprot.org/uniprot/M1E4M1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS07365 ^@ http://purl.uniprot.org/uniprot/M1E895 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/747365:THENA_RS06350 ^@ http://purl.uniprot.org/uniprot/M1E6L8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Forms a complex with TatA.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. http://togogenome.org/gene/747365:THENA_RS03525 ^@ http://purl.uniprot.org/uniprot/M1E894 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/747365:THENA_RS05040 ^@ http://purl.uniprot.org/uniprot/M1E7E9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS08600 ^@ http://purl.uniprot.org/uniprot/M1E5V6 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/747365:THENA_RS05915 ^@ http://purl.uniprot.org/uniprot/M1E862 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/747365:THENA_RS02030 ^@ http://purl.uniprot.org/uniprot/M1E683 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/747365:THENA_RS09120 ^@ http://purl.uniprot.org/uniprot/M1E8V8 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS00440 ^@ http://purl.uniprot.org/uniprot/M1E5I3 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/747365:THENA_RS07315 ^@ http://purl.uniprot.org/uniprot/M1E891 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters.|||Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. http://togogenome.org/gene/747365:THENA_RS01710 ^@ http://purl.uniprot.org/uniprot/M1E6F4 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/747365:THENA_RS08735 ^@ http://purl.uniprot.org/uniprot/M1E8S7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/747365:THENA_RS04120 ^@ http://purl.uniprot.org/uniprot/M1E7F2 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/747365:THENA_RS08420 ^@ http://purl.uniprot.org/uniprot/M1E7G0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS07885 ^@ http://purl.uniprot.org/uniprot/M1E8U1 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/747365:THENA_RS00960 ^@ http://purl.uniprot.org/uniprot/M1E766 ^@ Cofactor ^@ The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/747365:THENA_RS01035 ^@ http://purl.uniprot.org/uniprot/M1E681 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/747365:THENA_RS03995 ^@ http://purl.uniprot.org/uniprot/M1E7D7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/747365:THENA_RS02660 ^@ http://purl.uniprot.org/uniprot/M1E4H8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/747365:THENA_RS00810 ^@ http://purl.uniprot.org/uniprot/M1E741 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/747365:THENA_RS07400 ^@ http://purl.uniprot.org/uniprot/M1E8N5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS06135 ^@ http://purl.uniprot.org/uniprot/M1E6J0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS07265 ^@ http://purl.uniprot.org/uniprot/M1E886 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/747365:THENA_RS06420 ^@ http://purl.uniprot.org/uniprot/M1E8D2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/747365:THENA_RS08905 ^@ http://purl.uniprot.org/uniprot/M1E9I7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/747365:THENA_RS04425 ^@ http://purl.uniprot.org/uniprot/M1E754 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/747365:THENA_RS06625 ^@ http://purl.uniprot.org/uniprot/M1E969 ^@ Similarity ^@ Belongs to the IMPDH/GMPR family. http://togogenome.org/gene/747365:THENA_RS09615 ^@ http://purl.uniprot.org/uniprot/M1E8G4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS07235 ^@ http://purl.uniprot.org/uniprot/M1E5E2 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/747365:THENA_RS08725 ^@ http://purl.uniprot.org/uniprot/M1E7M4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/747365:THENA_RS00865 ^@ http://purl.uniprot.org/uniprot/M1E662 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/747365:THENA_RS03980 ^@ http://purl.uniprot.org/uniprot/M1E4Q7 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/747365:THENA_RS06210 ^@ http://purl.uniprot.org/uniprot/M1E8A9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/747365:THENA_RS00640 ^@ http://purl.uniprot.org/uniprot/M1E4U8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably interacts with PlsX. http://togogenome.org/gene/747365:THENA_RS03190 ^@ http://purl.uniprot.org/uniprot/M1E710 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/747365:THENA_RS03000 ^@ http://purl.uniprot.org/uniprot/M1E4K0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/747365:THENA_RS04265 ^@ http://purl.uniprot.org/uniprot/M1E4S0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpA family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/747365:THENA_RS05030 ^@ http://purl.uniprot.org/uniprot/M1E632 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/747365:THENA_RS02535 ^@ http://purl.uniprot.org/uniprot/M1E4G7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/747365:THENA_RS06945 ^@ http://purl.uniprot.org/uniprot/M1E5B6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS03255 ^@ http://purl.uniprot.org/uniprot/M1E6Q9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS02595 ^@ http://purl.uniprot.org/uniprot/M1E7V1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/747365:THENA_RS04875 ^@ http://purl.uniprot.org/uniprot/M1E7R3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS03330 ^@ http://purl.uniprot.org/uniprot/M1E732 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS08350 ^@ http://purl.uniprot.org/uniprot/M1E5R9 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/747365:THENA_RS05950 ^@ http://purl.uniprot.org/uniprot/M1E6F8 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/747365:THENA_RS08775 ^@ http://purl.uniprot.org/uniprot/M1E7N7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/747365:THENA_RS06655 ^@ http://purl.uniprot.org/uniprot/M1E8F7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS07800 ^@ http://purl.uniprot.org/uniprot/M1E8F1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the thymidylate synthase ThyX family.|||Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.|||Homotetramer. http://togogenome.org/gene/747365:THENA_RS03610 ^@ http://purl.uniprot.org/uniprot/M1E5M2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/747365:THENA_RS03150 ^@ http://purl.uniprot.org/uniprot/M1E4K8 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/747365:THENA_RS09035 ^@ http://purl.uniprot.org/uniprot/M1E7R7 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/747365:THENA_RS00340 ^@ http://purl.uniprot.org/uniprot/M1E6S8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS02280 ^@ http://purl.uniprot.org/uniprot/M1E4F2 ^@ Cofactor|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit. http://togogenome.org/gene/747365:THENA_RS02630 ^@ http://purl.uniprot.org/uniprot/M1E5B3 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/747365:THENA_RS04525 ^@ http://purl.uniprot.org/uniprot/M1E4T5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/747365:THENA_RS09575 ^@ http://purl.uniprot.org/uniprot/M1E4H9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS07820 ^@ http://purl.uniprot.org/uniprot/M1E5J8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS06100 ^@ http://purl.uniprot.org/uniprot/M1E925 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS06735 ^@ http://purl.uniprot.org/uniprot/M1E6R3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/747365:THENA_RS05565 ^@ http://purl.uniprot.org/uniprot/M1E7M7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/747365:THENA_RS09210 ^@ http://purl.uniprot.org/uniprot/M1E642 ^@ Function|||Similarity ^@ Belongs to the Thz kinase family.|||Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ). http://togogenome.org/gene/747365:THENA_RS09130 ^@ http://purl.uniprot.org/uniprot/M1E974 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/747365:THENA_RS00285 ^@ http://purl.uniprot.org/uniprot/M1E5F6 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/747365:THENA_RS04825 ^@ http://purl.uniprot.org/uniprot/M1E7Q4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS07735 ^@ http://purl.uniprot.org/uniprot/M1E743 ^@ Similarity ^@ Belongs to the NifH/BchL/ChlL family. http://togogenome.org/gene/747365:THENA_RS03530 ^@ http://purl.uniprot.org/uniprot/M1E775 ^@ Cofactor|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/747365:THENA_RS03675 ^@ http://purl.uniprot.org/uniprot/M1E8A5 ^@ Function|||Similarity|||Subunit ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Homodimer and homohexamer; in equilibrium.|||Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. http://togogenome.org/gene/747365:THENA_RS09610 ^@ http://purl.uniprot.org/uniprot/M1E715 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS00195 ^@ http://purl.uniprot.org/uniprot/M1E5M6 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. http://togogenome.org/gene/747365:THENA_RS08580 ^@ http://purl.uniprot.org/uniprot/M1E8Q3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/747365:THENA_RS06580 ^@ http://purl.uniprot.org/uniprot/M1E8E9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/747365:THENA_RS06840 ^@ http://purl.uniprot.org/uniprot/M1E5A7 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/747365:THENA_RS08150 ^@ http://purl.uniprot.org/uniprot/M1E7A7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS00765 ^@ http://purl.uniprot.org/uniprot/M1E620 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/747365:THENA_RS05110 ^@ http://purl.uniprot.org/uniprot/M1E4W9 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS03905 ^@ http://purl.uniprot.org/uniprot/M1E4Q3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS09075 ^@ http://purl.uniprot.org/uniprot/M1E9J4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/747365:THENA_RS07245 ^@ http://purl.uniprot.org/uniprot/M1E9B6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/747365:THENA_RS01370 ^@ http://purl.uniprot.org/uniprot/M1E7C5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/747365:THENA_RS03275 ^@ http://purl.uniprot.org/uniprot/M1E4L8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/747365:THENA_RS02655 ^@ http://purl.uniprot.org/uniprot/M1E5B5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/747365:THENA_RS00430 ^@ http://purl.uniprot.org/uniprot/M1E4S5 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/747365:THENA_RS07830 ^@ http://purl.uniprot.org/uniprot/M1E9E6 ^@ Similarity ^@ Belongs to the UPF0251 family. http://togogenome.org/gene/747365:THENA_RS04895 ^@ http://purl.uniprot.org/uniprot/M1E8N9 ^@ Function ^@ May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/747365:THENA_RS02130 ^@ http://purl.uniprot.org/uniprot/M1E7M6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/747365:THENA_RS00940 ^@ http://purl.uniprot.org/uniprot/M1E671 ^@ Similarity ^@ Belongs to the PstS family. http://togogenome.org/gene/747365:THENA_RS07670 ^@ http://purl.uniprot.org/uniprot/M1E8D4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Membrane http://togogenome.org/gene/747365:THENA_RS08780 ^@ http://purl.uniprot.org/uniprot/M1E5Z4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS06620 ^@ http://purl.uniprot.org/uniprot/M1E826 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/747365:THENA_RS01280 ^@ http://purl.uniprot.org/uniprot/M1E505 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnA subfamily.|||Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/747365:THENA_RS04565 ^@ http://purl.uniprot.org/uniprot/M1E4T8 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/747365:THENA_RS00500 ^@ http://purl.uniprot.org/uniprot/M1E5U6 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/747365:THENA_RS08945 ^@ http://purl.uniprot.org/uniprot/M1E8U4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 30 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/747365:THENA_RS00525 ^@ http://purl.uniprot.org/uniprot/M1E4T7 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/747365:THENA_RS05745 ^@ http://purl.uniprot.org/uniprot/M1E8Z0 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/747365:THENA_RS02615 ^@ http://purl.uniprot.org/uniprot/M1E6G3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/747365:THENA_RS00290 ^@ http://purl.uniprot.org/uniprot/M1E6R7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/747365:THENA_RS01955 ^@ http://purl.uniprot.org/uniprot/M1E4D1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS03540 ^@ http://purl.uniprot.org/uniprot/M1E4N6 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/747365:THENA_RS07350 ^@ http://purl.uniprot.org/uniprot/M1E8M9 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/747365:THENA_RS02590 ^@ http://purl.uniprot.org/uniprot/M1E6G0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/747365:THENA_RS00010 ^@ http://purl.uniprot.org/uniprot/M1E5I9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS05810 ^@ http://purl.uniprot.org/uniprot/M1E8Z7 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/747365:THENA_RS00880 ^@ http://purl.uniprot.org/uniprot/M1E5U1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/747365:THENA_RS04095 ^@ http://purl.uniprot.org/uniprot/M1E7E8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/747365:THENA_RS06335 ^@ http://purl.uniprot.org/uniprot/M1E800 ^@ Function ^@ Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/747365:THENA_RS00715 ^@ http://purl.uniprot.org/uniprot/M1E601 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/747365:THENA_RS07380 ^@ http://purl.uniprot.org/uniprot/M1E6Z5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/747365:THENA_RS02935 ^@ http://purl.uniprot.org/uniprot/M1E6K4 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/747365:THENA_RS06160 ^@ http://purl.uniprot.org/uniprot/M1E6J8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/747365:THENA_RS04505 ^@ http://purl.uniprot.org/uniprot/M1E765 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/747365:THENA_RS06910 ^@ http://purl.uniprot.org/uniprot/M1E6T5 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/747365:THENA_RS08965 ^@ http://purl.uniprot.org/uniprot/M1E614 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/747365:THENA_RS05090 ^@ http://purl.uniprot.org/uniprot/M1E7F8 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/747365:THENA_RS09200 ^@ http://purl.uniprot.org/uniprot/M1E979 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/747365:THENA_RS01290 ^@ http://purl.uniprot.org/uniprot/M1E5Y6 ^@ Caution|||Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnD subfamily.|||Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS04625 ^@ http://purl.uniprot.org/uniprot/M1E785 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/747365:THENA_RS02305 ^@ http://purl.uniprot.org/uniprot/M1E4F3 ^@ Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family. http://togogenome.org/gene/747365:THENA_RS08755 ^@ http://purl.uniprot.org/uniprot/M1E5Z0 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/747365:THENA_RS04915 ^@ http://purl.uniprot.org/uniprot/M1E7C7 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/747365:THENA_RS06095 ^@ http://purl.uniprot.org/uniprot/M1E7W5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/747365:THENA_RS00600 ^@ http://purl.uniprot.org/uniprot/M1E5L2 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/747365:THENA_RS00830 ^@ http://purl.uniprot.org/uniprot/M1E752 ^@ Function|||Similarity ^@ Belongs to the APS kinase family.|||Catalyzes the synthesis of activated sulfate. http://togogenome.org/gene/747365:THENA_RS06290 ^@ http://purl.uniprot.org/uniprot/M1E6L2 ^@ Similarity ^@ Belongs to the ycf81 family. http://togogenome.org/gene/747365:THENA_RS03890 ^@ http://purl.uniprot.org/uniprot/M1E8C6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/747365:THENA_RS00675 ^@ http://purl.uniprot.org/uniprot/M1E480 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/747365:THENA_RS02505 ^@ http://purl.uniprot.org/uniprot/M1E5A0 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS02585 ^@ http://purl.uniprot.org/uniprot/M1E4H0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/747365:THENA_RS09295 ^@ http://purl.uniprot.org/uniprot/M1E653 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS08485 ^@ http://purl.uniprot.org/uniprot/M1E9H1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS08220 ^@ http://purl.uniprot.org/uniprot/M1E8Y7 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/747365:THENA_RS03005 ^@ http://purl.uniprot.org/uniprot/M1E6L7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/747365:THENA_RS04070 ^@ http://purl.uniprot.org/uniprot/M1E4G7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/747365:THENA_RS08335 ^@ http://purl.uniprot.org/uniprot/M1E9G5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/747365:THENA_RS08340 ^@ http://purl.uniprot.org/uniprot/M1E902 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/747365:THENA_RS00770 ^@ http://purl.uniprot.org/uniprot/M1E4W4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS04855 ^@ http://purl.uniprot.org/uniprot/M1E604 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/747365:THENA_RS06270 ^@ http://purl.uniprot.org/uniprot/M1E565 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.|||Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.|||Homotetramer composed of a dimer of dimers. http://togogenome.org/gene/747365:THENA_RS08000 ^@ http://purl.uniprot.org/uniprot/M1E5L9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ArsB family.|||Belongs to the CitM (TC 2.A.11) transporter family.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS04255 ^@ http://purl.uniprot.org/uniprot/M1E7H0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpC family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/747365:THENA_RS07120 ^@ http://purl.uniprot.org/uniprot/M1E9A6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS05725 ^@ http://purl.uniprot.org/uniprot/M1E837 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SelA family.|||Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS02895 ^@ http://purl.uniprot.org/uniprot/M1E5E0 ^@ Similarity ^@ Belongs to the bacterial secretin family. http://togogenome.org/gene/747365:THENA_RS03370 ^@ http://purl.uniprot.org/uniprot/M1E6S7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS06860 ^@ http://purl.uniprot.org/uniprot/M1E6S9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/747365:THENA_RS00100 ^@ http://purl.uniprot.org/uniprot/M1E5C2 ^@ Function|||Similarity ^@ Belongs to the CheD family.|||Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis. http://togogenome.org/gene/747365:THENA_RS07625 ^@ http://purl.uniprot.org/uniprot/M1E9D3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/747365:THENA_RS01725 ^@ http://purl.uniprot.org/uniprot/M1E641 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/747365:THENA_RS02695 ^@ http://purl.uniprot.org/uniprot/M1E7W8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/747365:THENA_RS08315 ^@ http://purl.uniprot.org/uniprot/M1E8Z8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/747365:THENA_RS03765 ^@ http://purl.uniprot.org/uniprot/M1E5N6 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/747365:THENA_RS02920 ^@ http://purl.uniprot.org/uniprot/M1E5E3 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/747365:THENA_RS03395 ^@ http://purl.uniprot.org/uniprot/M1E6T1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/747365:THENA_RS03660 ^@ http://purl.uniprot.org/uniprot/M1E5M8 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/747365:THENA_RS08225 ^@ http://purl.uniprot.org/uniprot/M1E7C4 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/747365:THENA_RS00035 ^@ http://purl.uniprot.org/uniprot/M1E5J4 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/747365:THENA_RS06485 ^@ http://purl.uniprot.org/uniprot/M1E582 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS05560 ^@ http://purl.uniprot.org/uniprot/M1E502 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/747365:THENA_RS01545 ^@ http://purl.uniprot.org/uniprot/M1E621 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS00360 ^@ http://purl.uniprot.org/uniprot/M1E5H0 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/747365:THENA_RS04820 ^@ http://purl.uniprot.org/uniprot/M1E8N1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/747365:THENA_RS02220 ^@ http://purl.uniprot.org/uniprot/M1E572 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS02705 ^@ http://purl.uniprot.org/uniprot/M1E5C0 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/747365:THENA_RS04710 ^@ http://purl.uniprot.org/uniprot/M1E7N6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS02010 ^@ http://purl.uniprot.org/uniprot/M1E7L0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/747365:THENA_RS02170 ^@ http://purl.uniprot.org/uniprot/M1E4E5 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/747365:THENA_RS02000 ^@ http://purl.uniprot.org/uniprot/M1E4D4 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/747365:THENA_RS07685 ^@ http://purl.uniprot.org/uniprot/M1E737 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/747365:THENA_RS00975 ^@ http://purl.uniprot.org/uniprot/M1E492 ^@ Cofactor|||Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/747365:THENA_RS05635 ^@ http://purl.uniprot.org/uniprot/M1E509 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/747365:THENA_RS01205 ^@ http://purl.uniprot.org/uniprot/M1E4A2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/747365:THENA_RS04510 ^@ http://purl.uniprot.org/uniprot/M1E8J6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/747365:THENA_RS07150 ^@ http://purl.uniprot.org/uniprot/M1E8K8 ^@ Function|||Similarity ^@ Belongs to the LpxK family.|||Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). http://togogenome.org/gene/747365:THENA_RS00480 ^@ http://purl.uniprot.org/uniprot/M1E4T1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS09220 ^@ http://purl.uniprot.org/uniprot/M1E9K0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliN/MopA/SpaO family.|||Membrane http://togogenome.org/gene/747365:THENA_RS05355 ^@ http://purl.uniprot.org/uniprot/M1E8U3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS02700 ^@ http://purl.uniprot.org/uniprot/M1E6T3 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/747365:THENA_RS07835 ^@ http://purl.uniprot.org/uniprot/M1E8T2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpxP/Spy family.|||Periplasm http://togogenome.org/gene/747365:THENA_RS00605 ^@ http://purl.uniprot.org/uniprot/M1E6Y3 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/747365:THENA_RS03415 ^@ http://purl.uniprot.org/uniprot/M1E4M7 ^@ Similarity ^@ Belongs to the UPF0473 family. http://togogenome.org/gene/747365:THENA_RS01580 ^@ http://purl.uniprot.org/uniprot/M1E6E3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/747365:THENA_RS06465 ^@ http://purl.uniprot.org/uniprot/M1E956 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS07950 ^@ http://purl.uniprot.org/uniprot/M1E5L0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS04260 ^@ http://purl.uniprot.org/uniprot/M1E5S7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/747365:THENA_RS01535 ^@ http://purl.uniprot.org/uniprot/M1E522 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/747365:THENA_RS06050 ^@ http://purl.uniprot.org/uniprot/M1E921 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/747365:THENA_RS05550 ^@ http://purl.uniprot.org/uniprot/M1E815 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/747365:THENA_RS07155 ^@ http://purl.uniprot.org/uniprot/M1E6W1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS03045 ^@ http://purl.uniprot.org/uniprot/M1E5F8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/747365:THENA_RS05895 ^@ http://purl.uniprot.org/uniprot/M1E6F1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. N-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/747365:THENA_RS03625 ^@ http://purl.uniprot.org/uniprot/M1E8A1 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS07345 ^@ http://purl.uniprot.org/uniprot/M1E9C2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/747365:THENA_RS06705 ^@ http://purl.uniprot.org/uniprot/M1E8G3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS04285 ^@ http://purl.uniprot.org/uniprot/M1E683 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/747365:THENA_RS03350 ^@ http://purl.uniprot.org/uniprot/M1E868 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS03130 ^@ http://purl.uniprot.org/uniprot/M1E6N7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS08330 ^@ http://purl.uniprot.org/uniprot/M1E8M0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/747365:THENA_RS00405 ^@ http://purl.uniprot.org/uniprot/M1E459 ^@ Similarity ^@ Belongs to the transposase IS21/IS408/IS1162 family. http://togogenome.org/gene/747365:THENA_RS06795 ^@ http://purl.uniprot.org/uniprot/M1E842 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/747365:THENA_RS09700 ^@ http://purl.uniprot.org/uniprot/M1E814 ^@ Similarity ^@ Belongs to the alkaline phosphatase family. http://togogenome.org/gene/747365:THENA_RS03060 ^@ http://purl.uniprot.org/uniprot/M1E824 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/747365:THENA_RS00530 ^@ http://purl.uniprot.org/uniprot/M1E469 ^@ Similarity ^@ Belongs to the ETF-QO/FixC family. http://togogenome.org/gene/747365:THENA_RS03085 ^@ http://purl.uniprot.org/uniprot/M1E828 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/747365:THENA_RS00085 ^@ http://purl.uniprot.org/uniprot/M1E5K3 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/747365:THENA_RS02560 ^@ http://purl.uniprot.org/uniprot/M1E4G8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/747365:THENA_RS08205 ^@ http://purl.uniprot.org/uniprot/M1E5P6 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/747365:THENA_RS01575 ^@ http://purl.uniprot.org/uniprot/M1E7F4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/747365:THENA_RS09335 ^@ http://purl.uniprot.org/uniprot/M1E990 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/747365:THENA_RS06975 ^@ http://purl.uniprot.org/uniprot/M1E859 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/747365:THENA_RS03280 ^@ http://purl.uniprot.org/uniprot/M1E6R4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/747365:THENA_RS06870 ^@ http://purl.uniprot.org/uniprot/M1E849 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the PRA-PH family.|||In the N-terminal section; belongs to the PRA-CH family. http://togogenome.org/gene/747365:THENA_RS00935 ^@ http://purl.uniprot.org/uniprot/M1E763 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/747365:THENA_RS07355 ^@ http://purl.uniprot.org/uniprot/M1E6Z1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/747365:THENA_RS08745 ^@ http://purl.uniprot.org/uniprot/M1E945 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS04115 ^@ http://purl.uniprot.org/uniprot/M1E8F0 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/747365:THENA_RS04535 ^@ http://purl.uniprot.org/uniprot/M1E8J9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/747365:THENA_RS00220 ^@ http://purl.uniprot.org/uniprot/M1E5N2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/747365:THENA_RS08370 ^@ http://purl.uniprot.org/uniprot/M1E7F1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.|||Membrane http://togogenome.org/gene/747365:THENA_RS00615 ^@ http://purl.uniprot.org/uniprot/M1E4U5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/747365:THENA_RS08095 ^@ http://purl.uniprot.org/uniprot/M1E7A0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/747365:THENA_RS03885 ^@ http://purl.uniprot.org/uniprot/M1E6Z6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/747365:THENA_RS00755 ^@ http://purl.uniprot.org/uniprot/M1E5Q6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/747365:THENA_RS03990 ^@ http://purl.uniprot.org/uniprot/M1E8D9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/747365:THENA_RS03335 ^@ http://purl.uniprot.org/uniprot/M1E5I8 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/747365:THENA_RS07665 ^@ http://purl.uniprot.org/uniprot/M1E5I1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0053 family.|||Membrane http://togogenome.org/gene/747365:THENA_RS03535 ^@ http://purl.uniprot.org/uniprot/M1E5L7 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/747365:THENA_RS01395 ^@ http://purl.uniprot.org/uniprot/M1E7C9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/747365:THENA_RS04840 ^@ http://purl.uniprot.org/uniprot/M1E7B5 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/747365:THENA_RS09715 ^@ http://purl.uniprot.org/uniprot/M1E885 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/747365:THENA_RS02235 ^@ http://purl.uniprot.org/uniprot/M1E7N9 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/747365:THENA_RS03035 ^@ http://purl.uniprot.org/uniprot/M1E821 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/747365:THENA_RS02905 ^@ http://purl.uniprot.org/uniprot/M1E6K0 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/747365:THENA_RS00645 ^@ http://purl.uniprot.org/uniprot/M1E479 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS04790 ^@ http://purl.uniprot.org/uniprot/M1E7A7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS00635 ^@ http://purl.uniprot.org/uniprot/M1E5Y0 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/747365:THENA_RS08625 ^@ http://purl.uniprot.org/uniprot/M1E5W1 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/747365:THENA_RS02410 ^@ http://purl.uniprot.org/uniprot/M1E4F9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the XseA family.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS03790 ^@ http://purl.uniprot.org/uniprot/M1E5N8 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/747365:THENA_RS05350 ^@ http://purl.uniprot.org/uniprot/M1E7J9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS05075 ^@ http://purl.uniprot.org/uniprot/M1E7U6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS03110 ^@ http://purl.uniprot.org/uniprot/M1E832 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS08390 ^@ http://purl.uniprot.org/uniprot/M1E908 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS04705 ^@ http://purl.uniprot.org/uniprot/M1E8L9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/747365:THENA_RS08605 ^@ http://purl.uniprot.org/uniprot/M1E8Q6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/747365:THENA_RS09160 ^@ http://purl.uniprot.org/uniprot/M1E636 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/747365:THENA_RS06675 ^@ http://purl.uniprot.org/uniprot/M1E973 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/747365:THENA_RS03750 ^@ http://purl.uniprot.org/uniprot/M1E6Y2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer. http://togogenome.org/gene/747365:THENA_RS02965 ^@ http://purl.uniprot.org/uniprot/M1E809 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/747365:THENA_RS00065 ^@ http://purl.uniprot.org/uniprot/M1E4L9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/747365:THENA_RS06980 ^@ http://purl.uniprot.org/uniprot/M1E999 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/747365:THENA_RS03315 ^@ http://purl.uniprot.org/uniprot/M1E4M0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/747365:THENA_RS07505 ^@ http://purl.uniprot.org/uniprot/M1E9C8 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/747365:THENA_RS05195 ^@ http://purl.uniprot.org/uniprot/M1E8S3 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/747365:THENA_RS08995 ^@ http://purl.uniprot.org/uniprot/M1E8U8 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/747365:THENA_RS03215 ^@ http://purl.uniprot.org/uniprot/M1E714 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.|||Membrane http://togogenome.org/gene/747365:THENA_RS03380 ^@ http://purl.uniprot.org/uniprot/M1E740 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/747365:THENA_RS05775 ^@ http://purl.uniprot.org/uniprot/M1E7Q7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/747365:THENA_RS03735 ^@ http://purl.uniprot.org/uniprot/M1E7A2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/747365:THENA_RS08300 ^@ http://purl.uniprot.org/uniprot/M1E5R1 ^@ Activity Regulation|||Caution|||Domain|||Function|||Similarity ^@ Belongs to the GlnD family.|||Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.|||Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity. http://togogenome.org/gene/747365:THENA_RS07565 ^@ http://purl.uniprot.org/uniprot/M1E721 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/747365:THENA_RS07025 ^@ http://purl.uniprot.org/uniprot/M1E5C3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS04010 ^@ http://purl.uniprot.org/uniprot/M1E712 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons. http://togogenome.org/gene/747365:THENA_RS06525 ^@ http://purl.uniprot.org/uniprot/M1E960 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/747365:THENA_RS06505 ^@ http://purl.uniprot.org/uniprot/M1E6N6 ^@ Similarity ^@ Belongs to the UPF0597 family. http://togogenome.org/gene/747365:THENA_RS05805 ^@ http://purl.uniprot.org/uniprot/M1E7R2 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/747365:THENA_RS04480 ^@ http://purl.uniprot.org/uniprot/M1E761 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/747365:THENA_RS04785 ^@ http://purl.uniprot.org/uniprot/M1E4V0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS00620 ^@ http://purl.uniprot.org/uniprot/M1E476 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/747365:THENA_RS06150 ^@ http://purl.uniprot.org/uniprot/M1E931 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/747365:THENA_RS01670 ^@ http://purl.uniprot.org/uniprot/M1E634 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/747365:THENA_RS02645 ^@ http://purl.uniprot.org/uniprot/M1E7V9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/747365:THENA_RS06240 ^@ http://purl.uniprot.org/uniprot/M1E6K7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/747365:THENA_RS05290 ^@ http://purl.uniprot.org/uniprot/M1E7J1 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/747365:THENA_RS07325 ^@ http://purl.uniprot.org/uniprot/M1E8M6 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). http://togogenome.org/gene/747365:THENA_RS01210 ^@ http://purl.uniprot.org/uniprot/M1E5X7 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/747365:THENA_RS05150 ^@ http://purl.uniprot.org/uniprot/M1E7W0 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/747365:THENA_RS09195 ^@ http://purl.uniprot.org/uniprot/M1E9J9 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/747365:THENA_RS07015 ^@ http://purl.uniprot.org/uniprot/M1E8J5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DsrC/TusE family.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS07125 ^@ http://purl.uniprot.org/uniprot/M1E8K5 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/747365:THENA_RS04890 ^@ http://purl.uniprot.org/uniprot/M1E7C2 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/747365:THENA_RS03925 ^@ http://purl.uniprot.org/uniprot/M1E5P9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. http://togogenome.org/gene/747365:THENA_RS04975 ^@ http://purl.uniprot.org/uniprot/M1E7T0 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. http://togogenome.org/gene/747365:THENA_RS00745 ^@ http://purl.uniprot.org/uniprot/M1E4W1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS02855 ^@ http://purl.uniprot.org/uniprot/M1E6J4 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/747365:THENA_RS02165 ^@ http://purl.uniprot.org/uniprot/M1E566 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FBPase class 1 family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS08545 ^@ http://purl.uniprot.org/uniprot/M1E7I1 ^@ Similarity ^@ Belongs to the phosphate/phosphite/phosphonate binding protein family. http://togogenome.org/gene/747365:THENA_RS08930 ^@ http://purl.uniprot.org/uniprot/M1E959 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.|||Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/747365:THENA_RS08590 ^@ http://purl.uniprot.org/uniprot/M1E926 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/747365:THENA_RS05000 ^@ http://purl.uniprot.org/uniprot/M1E7T5 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/747365:THENA_RS07420 ^@ http://purl.uniprot.org/uniprot/M1E8A0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/747365:THENA_RS02570 ^@ http://purl.uniprot.org/uniprot/M1E7U5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/747365:THENA_RS04905 ^@ http://purl.uniprot.org/uniprot/M1E611 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/747365:THENA_RS03705 ^@ http://purl.uniprot.org/uniprot/M1E8A8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/747365:THENA_RS00470 ^@ http://purl.uniprot.org/uniprot/M1E6V2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS00120 ^@ http://purl.uniprot.org/uniprot/M1E4M5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/747365:THENA_RS06790 ^@ http://purl.uniprot.org/uniprot/M1E5A3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS06890 ^@ http://purl.uniprot.org/uniprot/M1E5B2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/747365:THENA_RS07330 ^@ http://purl.uniprot.org/uniprot/M1E6Y7 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/747365:THENA_RS06405 ^@ http://purl.uniprot.org/uniprot/M1E576 ^@ Function ^@ Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate. http://togogenome.org/gene/747365:THENA_RS01415 ^@ http://purl.uniprot.org/uniprot/M1E603 ^@ Similarity ^@ Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family. http://togogenome.org/gene/747365:THENA_RS06215 ^@ http://purl.uniprot.org/uniprot/M1E6K3 ^@ Similarity|||Subunit ^@ Belongs to the PdxA family. PdxA2 subfamily.|||Homodimer. http://togogenome.org/gene/747365:THENA_RS09225 ^@ http://purl.uniprot.org/uniprot/M1E981 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Membrane http://togogenome.org/gene/747365:THENA_RS09325 ^@ http://purl.uniprot.org/uniprot/M1E8X5 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/747365:THENA_RS03305 ^@ http://purl.uniprot.org/uniprot/M1E728 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/747365:THENA_RS04640 ^@ http://purl.uniprot.org/uniprot/M1E5X6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/747365:THENA_RS05220 ^@ http://purl.uniprot.org/uniprot/M1E8S5 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/747365:THENA_RS05100 ^@ http://purl.uniprot.org/uniprot/M1E7V0 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/747365:THENA_RS07805 ^@ http://purl.uniprot.org/uniprot/M1E9E4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/747365:THENA_RS07970 ^@ http://purl.uniprot.org/uniprot/M1E779 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/747365:THENA_RS09050 ^@ http://purl.uniprot.org/uniprot/M1E9J3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS08210 ^@ http://purl.uniprot.org/uniprot/M1E8K2 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/747365:THENA_RS03620 ^@ http://purl.uniprot.org/uniprot/M1E6W7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/747365:THENA_RS07645 ^@ http://purl.uniprot.org/uniprot/M1E8D1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS05830 ^@ http://purl.uniprot.org/uniprot/M1E7R6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS02800 ^@ http://purl.uniprot.org/uniprot/M1E4I7 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/747365:THENA_RS03515 ^@ http://purl.uniprot.org/uniprot/M1E4N4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-C family. DnaE subfamily.|||Cytoplasm|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase. http://togogenome.org/gene/747365:THENA_RS08050 ^@ http://purl.uniprot.org/uniprot/M1E793 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell membrane|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/747365:THENA_RS07260 ^@ http://purl.uniprot.org/uniprot/M1E5E4 ^@ Similarity ^@ Belongs to the Ahb/Nir family. http://togogenome.org/gene/747365:THENA_RS09375 ^@ http://purl.uniprot.org/uniprot/M1E8X9 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/747365:THENA_RS06550 ^@ http://purl.uniprot.org/uniprot/M1E962 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS01355 ^@ http://purl.uniprot.org/uniprot/M1E510 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS07550 ^@ http://purl.uniprot.org/uniprot/M1E8B7 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS07990 ^@ http://purl.uniprot.org/uniprot/M1E8V7 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/747365:THENA_RS08120 ^@ http://purl.uniprot.org/uniprot/M1E7A4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HCP family.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 hybrid [4Fe-2O-2S] cluster.|||Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS09135 ^@ http://purl.uniprot.org/uniprot/M1E7S8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS07165 ^@ http://purl.uniprot.org/uniprot/M1E878 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/747365:THENA_RS02870 ^@ http://purl.uniprot.org/uniprot/M1E5D8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/747365:THENA_RS08325 ^@ http://purl.uniprot.org/uniprot/M1E5R6 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/747365:THENA_RS09355 ^@ http://purl.uniprot.org/uniprot/M1E9K6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/747365:THENA_RS09025 ^@ http://purl.uniprot.org/uniprot/M1E9J2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS03650 ^@ http://purl.uniprot.org/uniprot/M1E8A2 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/747365:THENA_RS04610 ^@ http://purl.uniprot.org/uniprot/M1E5X3 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/747365:THENA_RS06755 ^@ http://purl.uniprot.org/uniprot/M1E8G8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/747365:THENA_RS06775 ^@ http://purl.uniprot.org/uniprot/M1E982 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DsrC/TusE family.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS09265 ^@ http://purl.uniprot.org/uniprot/M1E8W8 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/747365:THENA_RS02865 ^@ http://purl.uniprot.org/uniprot/M1E6V3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS02205 ^@ http://purl.uniprot.org/uniprot/M1E6B3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/747365:THENA_RS05595 ^@ http://purl.uniprot.org/uniprot/M1E8X7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/747365:THENA_RS02480 ^@ http://purl.uniprot.org/uniprot/M1E597 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/747365:THENA_RS01360 ^@ http://purl.uniprot.org/uniprot/M1E4A8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/747365:THENA_RS02035 ^@ http://purl.uniprot.org/uniprot/M1E7L3 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/747365:THENA_RS09255 ^@ http://purl.uniprot.org/uniprot/M1E7U4 ^@ Similarity ^@ Belongs to the FlgD family. http://togogenome.org/gene/747365:THENA_RS02100 ^@ http://purl.uniprot.org/uniprot/M1E4E0 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/747365:THENA_RS03450 ^@ http://purl.uniprot.org/uniprot/M1E889 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/747365:THENA_RS01835 ^@ http://purl.uniprot.org/uniprot/M1E6G9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS00790 ^@ http://purl.uniprot.org/uniprot/M1E629 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/747365:THENA_RS06155 ^@ http://purl.uniprot.org/uniprot/M1E8A4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS03310 ^@ http://purl.uniprot.org/uniprot/M1E5I5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/747365:THENA_RS01740 ^@ http://purl.uniprot.org/uniprot/M1E536 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/747365:THENA_RS03635 ^@ http://purl.uniprot.org/uniprot/M1E5M4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/747365:THENA_RS05280 ^@ http://purl.uniprot.org/uniprot/M1E672 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/747365:THENA_RS00015 ^@ http://purl.uniprot.org/uniprot/M1E4L3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/747365:THENA_RS06535 ^@ http://purl.uniprot.org/uniprot/M1E6N9 ^@ Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers). http://togogenome.org/gene/747365:THENA_RS00520 ^@ http://purl.uniprot.org/uniprot/M1E5V2 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/747365:THENA_RS02985 ^@ http://purl.uniprot.org/uniprot/M1E813 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/747365:THENA_RS08235 ^@ http://purl.uniprot.org/uniprot/M1E8K6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/747365:THENA_RS06835 ^@ http://purl.uniprot.org/uniprot/M1E6S5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/747365:THENA_RS08215 ^@ http://purl.uniprot.org/uniprot/M1E9G0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M3B family.|||Binds 1 zinc ion.|||Has oligopeptidase activity and degrades a variety of small bioactive peptides. http://togogenome.org/gene/747365:THENA_RS03140 ^@ http://purl.uniprot.org/uniprot/M1E701 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/747365:THENA_RS03645 ^@ http://purl.uniprot.org/uniprot/M1E6X0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Cell membrane|||Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/747365:THENA_RS03160 ^@ http://purl.uniprot.org/uniprot/M1E840 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/747365:THENA_RS01430 ^@ http://purl.uniprot.org/uniprot/M1E515 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/747365:THENA_RS01730 ^@ http://purl.uniprot.org/uniprot/M1E7H3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HupC/HyaC/HydC family.|||Membrane http://togogenome.org/gene/747365:THENA_RS02515 ^@ http://purl.uniprot.org/uniprot/M1E6F0 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/747365:THENA_RS05970 ^@ http://purl.uniprot.org/uniprot/M1E872 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/747365:THENA_RS09470 ^@ http://purl.uniprot.org/uniprot/M1E5R4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/747365:THENA_RS01150 ^@ http://purl.uniprot.org/uniprot/M1E4A0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS08470 ^@ http://purl.uniprot.org/uniprot/M1E7G8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endonuclease V family.|||Cytoplasm|||DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. http://togogenome.org/gene/747365:THENA_RS03455 ^@ http://purl.uniprot.org/uniprot/M1E762 ^@ Function|||Similarity ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily. http://togogenome.org/gene/747365:THENA_RS03100 ^@ http://purl.uniprot.org/uniprot/M1E4K6 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/747365:THENA_RS06250 ^@ http://purl.uniprot.org/uniprot/M1E7Z1 ^@ Similarity ^@ Belongs to the pyruvate kinase family.|||In the C-terminal section; belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/747365:THENA_RS07660 ^@ http://purl.uniprot.org/uniprot/M1E733 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS04470 ^@ http://purl.uniprot.org/uniprot/M1E5V4 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/747365:THENA_RS07385 ^@ http://purl.uniprot.org/uniprot/M1E5F4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS09240 ^@ http://purl.uniprot.org/uniprot/M1E8W7 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/747365:THENA_RS00610 ^@ http://purl.uniprot.org/uniprot/M1E5X4 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/747365:THENA_RS08750 ^@ http://purl.uniprot.org/uniprot/M1E7N4 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/747365:THENA_RS00170 ^@ http://purl.uniprot.org/uniprot/M1E5M0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS08015 ^@ http://purl.uniprot.org/uniprot/M1E8W1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).|||Homodimer. http://togogenome.org/gene/747365:THENA_RS06145 ^@ http://purl.uniprot.org/uniprot/M1E7X9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/747365:THENA_RS08670 ^@ http://purl.uniprot.org/uniprot/M1E930 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgI family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/747365:THENA_RS06845 ^@ http://purl.uniprot.org/uniprot/M1E846 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS07510 ^@ http://purl.uniprot.org/uniprot/M1E8P6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS01200 ^@ http://purl.uniprot.org/uniprot/M1E4Z9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS02520 ^@ http://purl.uniprot.org/uniprot/M1E7T6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/747365:THENA_RS09385 ^@ http://purl.uniprot.org/uniprot/M1E994 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/747365:THENA_RS01240 ^@ http://purl.uniprot.org/uniprot/M1E5Y1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/747365:THENA_RS04380 ^@ http://purl.uniprot.org/uniprot/M1E8H8 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/747365:THENA_RS06585 ^@ http://purl.uniprot.org/uniprot/M1E6P4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS07390 ^@ http://purl.uniprot.org/uniprot/M1E898 ^@ Similarity ^@ Belongs to the acylphosphatase family.|||Belongs to the carbamoyltransferase HypF family. http://togogenome.org/gene/747365:THENA_RS05860 ^@ http://purl.uniprot.org/uniprot/M1E904 ^@ Cofactor ^@ Binds 4 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/747365:THENA_RS02675 ^@ http://purl.uniprot.org/uniprot/M1E6T0 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/747365:THENA_RS02805 ^@ http://purl.uniprot.org/uniprot/M1E6I8 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/747365:THENA_RS09405 ^@ http://purl.uniprot.org/uniprot/M1E9K8 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/747365:THENA_RS04725 ^@ http://purl.uniprot.org/uniprot/M1E4U7 ^@ Similarity ^@ Belongs to the WrbA family. http://togogenome.org/gene/747365:THENA_RS03205 ^@ http://purl.uniprot.org/uniprot/M1E6Q0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS06400 ^@ http://purl.uniprot.org/uniprot/M1E6M4 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/747365:THENA_RS07620 ^@ http://purl.uniprot.org/uniprot/M1E8C8 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/747365:THENA_RS00820 ^@ http://purl.uniprot.org/uniprot/M1E4X0 ^@ Similarity ^@ Belongs to the FtsK/SpoIIIE/SftA family. http://togogenome.org/gene/747365:THENA_RS00750 ^@ http://purl.uniprot.org/uniprot/M1E483 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/747365:THENA_RS06170 ^@ http://purl.uniprot.org/uniprot/M1E7Y1 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/747365:THENA_RS09370 ^@ http://purl.uniprot.org/uniprot/M1E660 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/747365:THENA_RS08100 ^@ http://purl.uniprot.org/uniprot/M1E5N0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS00685 ^@ http://purl.uniprot.org/uniprot/M1E704 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS03220 ^@ http://purl.uniprot.org/uniprot/M1E5H7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.|||Membrane http://togogenome.org/gene/747365:THENA_RS01775 ^@ http://purl.uniprot.org/uniprot/M1E647 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/747365:THENA_RS07395 ^@ http://purl.uniprot.org/uniprot/M1E9C4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS04100 ^@ http://purl.uniprot.org/uniprot/M1E5R3 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/747365:THENA_RS00860 ^@ http://purl.uniprot.org/uniprot/M1E756 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/747365:THENA_RS08540 ^@ http://purl.uniprot.org/uniprot/M1E922 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/747365:THENA_RS07340 ^@ http://purl.uniprot.org/uniprot/M1E893 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS00275 ^@ http://purl.uniprot.org/uniprot/M1E4Q1 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/747365:THENA_RS02510 ^@ http://purl.uniprot.org/uniprot/M1E4G5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. http://togogenome.org/gene/747365:THENA_RS04320 ^@ http://purl.uniprot.org/uniprot/M1E4S3 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS00955 ^@ http://purl.uniprot.org/uniprot/M1E5V0 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/747365:THENA_RS02760 ^@ http://purl.uniprot.org/uniprot/M1E6U0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DtxR/MntR family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/747365:THENA_RS01195 ^@ http://purl.uniprot.org/uniprot/M1E6A1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/747365:THENA_RS06665 ^@ http://purl.uniprot.org/uniprot/M1E594 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/747365:THENA_RS06935 ^@ http://purl.uniprot.org/uniprot/M1E8I7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS04000 ^@ http://purl.uniprot.org/uniprot/M1E5Q5 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS01970 ^@ http://purl.uniprot.org/uniprot/M1E6I5 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/747365:THENA_RS07615 ^@ http://purl.uniprot.org/uniprot/M1E5H6 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/747365:THENA_RS02670 ^@ http://purl.uniprot.org/uniprot/M1E7W4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/747365:THENA_RS02950 ^@ http://purl.uniprot.org/uniprot/M1E5E6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/747365:THENA_RS01300 ^@ http://purl.uniprot.org/uniprot/M1E6B4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 130 family. http://togogenome.org/gene/747365:THENA_RS06080 ^@ http://purl.uniprot.org/uniprot/M1E884 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/747365:THENA_RS08950 ^@ http://purl.uniprot.org/uniprot/M1E9I9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/747365:THENA_RS06575 ^@ http://purl.uniprot.org/uniprot/M1E964 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/747365:THENA_RS06515 ^@ http://purl.uniprot.org/uniprot/M1E584 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/747365:THENA_RS01020 ^@ http://purl.uniprot.org/uniprot/M1E4Y8 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/747365:THENA_RS05210 ^@ http://purl.uniprot.org/uniprot/M1E4X4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS03080 ^@ http://purl.uniprot.org/uniprot/M1E6N0 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/747365:THENA_RS03820 ^@ http://purl.uniprot.org/uniprot/M1E4P9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/747365:THENA_RS08635 ^@ http://purl.uniprot.org/uniprot/M1E9H7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.|||Belongs to the FliW family.|||Cytoplasm|||Interacts with translational regulator CsrA and flagellin(s). http://togogenome.org/gene/747365:THENA_RS07115 ^@ http://purl.uniprot.org/uniprot/M1E874 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS07855 ^@ http://purl.uniprot.org/uniprot/M1E9E7 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/747365:THENA_RS00850 ^@ http://purl.uniprot.org/uniprot/M1E487 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/747365:THENA_RS02975 ^@ http://purl.uniprot.org/uniprot/M1E5E9 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/747365:THENA_RS07775 ^@ http://purl.uniprot.org/uniprot/M1E8E7 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/747365:THENA_RS03180 ^@ http://purl.uniprot.org/uniprot/M1E6P7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS03050 ^@ http://purl.uniprot.org/uniprot/M1E4K3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/747365:THENA_RS06130 ^@ http://purl.uniprot.org/uniprot/M1E896 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/747365:THENA_RS09115 ^@ http://purl.uniprot.org/uniprot/M1E630 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/747365:THENA_RS09760 ^@ http://purl.uniprot.org/uniprot/M1E996 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/747365:THENA_RS01310 ^@ http://purl.uniprot.org/uniprot/M1E4A6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS03845 ^@ http://purl.uniprot.org/uniprot/M1E4Q0 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/747365:THENA_RS03445 ^@ http://purl.uniprot.org/uniprot/M1E6V1 ^@ Similarity ^@ Belongs to the transpeptidase family. http://togogenome.org/gene/747365:THENA_RS03325 ^@ http://purl.uniprot.org/uniprot/M1E863 ^@ Similarity ^@ Belongs to the transpeptidase family. http://togogenome.org/gene/747365:THENA_RS05025 ^@ http://purl.uniprot.org/uniprot/M1E7T9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/747365:THENA_RS08825 ^@ http://purl.uniprot.org/uniprot/M1E9I4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/747365:THENA_RS00105 ^@ http://purl.uniprot.org/uniprot/M1E6M8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliQ/MopD/SpaQ family.|||Membrane http://togogenome.org/gene/747365:THENA_RS05840 ^@ http://purl.uniprot.org/uniprot/M1E850 ^@ Cofactor ^@ Binds 4 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/747365:THENA_RS03345 ^@ http://purl.uniprot.org/uniprot/M1E6S1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS04860 ^@ http://purl.uniprot.org/uniprot/M1E4V4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS02860 ^@ http://purl.uniprot.org/uniprot/M1E7Y9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/747365:THENA_RS08500 ^@ http://purl.uniprot.org/uniprot/M1E5U0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/747365:THENA_RS06200 ^@ http://purl.uniprot.org/uniprot/M1E7Y5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/747365:THENA_RS06085 ^@ http://purl.uniprot.org/uniprot/M1E6H8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/747365:THENA_RS03630 ^@ http://purl.uniprot.org/uniprot/M1E786 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/747365:THENA_RS02955 ^@ http://purl.uniprot.org/uniprot/M1E4J5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/747365:THENA_RS00060 ^@ http://purl.uniprot.org/uniprot/M1E5K0 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/747365:THENA_RS04930 ^@ http://purl.uniprot.org/uniprot/M1E615 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/747365:THENA_RS08705 ^@ http://purl.uniprot.org/uniprot/M1E5X8 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/747365:THENA_RS03495 ^@ http://purl.uniprot.org/uniprot/M1E6V6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/747365:THENA_RS04910 ^@ http://purl.uniprot.org/uniprot/M1E4V7 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.|||May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/747365:THENA_RS04880 ^@ http://purl.uniprot.org/uniprot/M1E607 ^@ Function|||Similarity ^@ Belongs to the OMP decarboxylase family.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). http://togogenome.org/gene/747365:THENA_RS00225 ^@ http://purl.uniprot.org/uniprot/M1E4P1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/747365:THENA_RS01400 ^@ http://purl.uniprot.org/uniprot/M1E6C4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/747365:THENA_RS08305 ^@ http://purl.uniprot.org/uniprot/M1E8L5 ^@ Similarity ^@ Belongs to the peptidase M20 family. http://togogenome.org/gene/747365:THENA_RS06260 ^@ http://purl.uniprot.org/uniprot/M1E8B6 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/747365:THENA_RS08615 ^@ http://purl.uniprot.org/uniprot/M1E927 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Membrane http://togogenome.org/gene/747365:THENA_RS06645 ^@ http://purl.uniprot.org/uniprot/M1E829 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/747365:THENA_RS03805 ^@ http://purl.uniprot.org/uniprot/M1E8B9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/747365:THENA_RS01870 ^@ http://purl.uniprot.org/uniprot/M1E4C8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS03555 ^@ http://purl.uniprot.org/uniprot/M1E778 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/747365:THENA_RS08040 ^@ http://purl.uniprot.org/uniprot/M1E9F4 ^@ Similarity ^@ Belongs to the DNA polymerase type-Y family. http://togogenome.org/gene/747365:THENA_RS06900 ^@ http://purl.uniprot.org/uniprot/M1E993 ^@ Similarity ^@ Belongs to the rubredoxin family. http://togogenome.org/gene/747365:THENA_RS02355 ^@ http://purl.uniprot.org/uniprot/M1E4F6 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/747365:THENA_RS00985 ^@ http://purl.uniprot.org/uniprot/M1E769 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/747365:THENA_RS06030 ^@ http://purl.uniprot.org/uniprot/M1E544 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/747365:THENA_RS05285 ^@ http://purl.uniprot.org/uniprot/M1E4Y0 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/747365:THENA_RS02580 ^@ http://purl.uniprot.org/uniprot/M1E5A8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/747365:THENA_RS05010 ^@ http://purl.uniprot.org/uniprot/M1E4W3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS03730 ^@ http://purl.uniprot.org/uniprot/M1E8B1 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/747365:THENA_RS04925 ^@ http://purl.uniprot.org/uniprot/M1E7S2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/747365:THENA_RS08410 ^@ http://purl.uniprot.org/uniprot/M1E9G8 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS05905 ^@ http://purl.uniprot.org/uniprot/M1E7T2 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/747365:THENA_RS02665 ^@ http://purl.uniprot.org/uniprot/M1E6H0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/747365:THENA_RS03695 ^@ http://purl.uniprot.org/uniprot/M1E6X6 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS01600 ^@ http://purl.uniprot.org/uniprot/M1E7F7 ^@ Function|||Similarity ^@ Belongs to the type-2 OGG1 family.|||Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA. Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites). http://togogenome.org/gene/747365:THENA_RS04155 ^@ http://purl.uniprot.org/uniprot/M1E4R5 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/747365:THENA_RS03785 ^@ http://purl.uniprot.org/uniprot/M1E7A9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/747365:THENA_RS03145 ^@ http://purl.uniprot.org/uniprot/M1E5G8 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/747365:THENA_RS06075 ^@ http://purl.uniprot.org/uniprot/M1E924 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/747365:THENA_RS07425 ^@ http://purl.uniprot.org/uniprot/M1E9C5 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/747365:THENA_RS09000 ^@ http://purl.uniprot.org/uniprot/M1E9J1 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/747365:THENA_RS08925 ^@ http://purl.uniprot.org/uniprot/M1E9I8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.|||Membrane http://togogenome.org/gene/747365:THENA_RS06695 ^@ http://purl.uniprot.org/uniprot/M1E833 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/747365:THENA_RS06560 ^@ http://purl.uniprot.org/uniprot/M1E6P2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/747365:THENA_RS02525 ^@ http://purl.uniprot.org/uniprot/M1E6Q8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/747365:THENA_RS02135 ^@ http://purl.uniprot.org/uniprot/M1E6K1 ^@ Similarity ^@ Belongs to the RuBisCO large chain family. http://togogenome.org/gene/747365:THENA_RS08355 ^@ http://purl.uniprot.org/uniprot/M1E8M3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/747365:THENA_RS05515 ^@ http://purl.uniprot.org/uniprot/M1E7M0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Membrane http://togogenome.org/gene/747365:THENA_RS02555 ^@ http://purl.uniprot.org/uniprot/M1E5A5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/747365:THENA_RS00080 ^@ http://purl.uniprot.org/uniprot/M1E6M0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/747365:THENA_RS02565 ^@ http://purl.uniprot.org/uniprot/M1E6F7 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/747365:THENA_RS03965 ^@ http://purl.uniprot.org/uniprot/M1E8D6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/747365:THENA_RS05345 ^@ http://purl.uniprot.org/uniprot/M1E4Y5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS04990 ^@ http://purl.uniprot.org/uniprot/M1E7E0 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/747365:THENA_RS08720 ^@ http://purl.uniprot.org/uniprot/M1E939 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/747365:THENA_RS08310 ^@ http://purl.uniprot.org/uniprot/M1E9G4 ^@ Function|||Similarity ^@ Belongs to the RapZ-like family.|||Displays ATPase and GTPase activities. http://togogenome.org/gene/747365:THENA_RS01995 ^@ http://purl.uniprot.org/uniprot/M1E552 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/747365:THENA_RS07095 ^@ http://purl.uniprot.org/uniprot/M1E9A3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/747365:THENA_RS01315 ^@ http://purl.uniprot.org/uniprot/M1E5Y9 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/747365:THENA_RS02835 ^@ http://purl.uniprot.org/uniprot/M1E7Y2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/747365:THENA_RS00460 ^@ http://purl.uniprot.org/uniprot/M1E463 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/747365:THENA_RS08645 ^@ http://purl.uniprot.org/uniprot/M1E7K2 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/747365:THENA_RS05455 ^@ http://purl.uniprot.org/uniprot/M1E7L1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.|||Membrane http://togogenome.org/gene/747365:THENA_RS02605 ^@ http://purl.uniprot.org/uniprot/M1E5B0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/747365:THENA_RS04995 ^@ http://purl.uniprot.org/uniprot/M1E8Q1 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/747365:THENA_RS00630 ^@ http://purl.uniprot.org/uniprot/M1E6Z0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/747365:THENA_RS08180 ^@ http://purl.uniprot.org/uniprot/M1E5P2 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/747365:THENA_RS02455 ^@ http://purl.uniprot.org/uniprot/M1E595 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS06440 ^@ http://purl.uniprot.org/uniprot/M1E954 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS05430 ^@ http://purl.uniprot.org/uniprot/M1E7K7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS04980 ^@ http://purl.uniprot.org/uniprot/M1E623 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/747365:THENA_RS05360 ^@ http://purl.uniprot.org/uniprot/M1E7Y6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS03265 ^@ http://purl.uniprot.org/uniprot/M1E722 ^@ Function|||Similarity ^@ Belongs to the QueH family.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). http://togogenome.org/gene/747365:THENA_RS04015 ^@ http://purl.uniprot.org/uniprot/M1E8E2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/747365:THENA_RS02625 ^@ http://purl.uniprot.org/uniprot/M1E6S4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/747365:THENA_RS02155 ^@ http://purl.uniprot.org/uniprot/M1E7M9 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/747365:THENA_RS04105 ^@ http://purl.uniprot.org/uniprot/M1E4R2 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/747365:THENA_RS00625 ^@ http://purl.uniprot.org/uniprot/M1E5L8 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/747365:THENA_RS02795 ^@ http://purl.uniprot.org/uniprot/M1E5C9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/747365:THENA_RS03585 ^@ http://purl.uniprot.org/uniprot/M1E6W4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS00305 ^@ http://purl.uniprot.org/uniprot/M1E447 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/747365:THENA_RS03070 ^@ http://purl.uniprot.org/uniprot/M1E5G0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/747365:THENA_RS01130 ^@ http://purl.uniprot.org/uniprot/M1E5X1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Membrane http://togogenome.org/gene/747365:THENA_RS04580 ^@ http://purl.uniprot.org/uniprot/M1E7L8 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/747365:THENA_RS05070 ^@ http://purl.uniprot.org/uniprot/M1E8R0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/747365:THENA_RS03010 ^@ http://purl.uniprot.org/uniprot/M1E817 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/747365:THENA_RS00315 ^@ http://purl.uniprot.org/uniprot/M1E6S2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS06540 ^@ http://purl.uniprot.org/uniprot/M1E586 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/747365:THENA_RS01350 ^@ http://purl.uniprot.org/uniprot/M1E6B8 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/747365:THENA_RS06530 ^@ http://purl.uniprot.org/uniprot/M1E8E3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS08835 ^@ http://purl.uniprot.org/uniprot/M1E7P4 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated Csm5 family.|||This subunit might be involved in maturation of a crRNA intermediate to its mature form. http://togogenome.org/gene/747365:THENA_RS00895 ^@ http://purl.uniprot.org/uniprot/M1E4X9 ^@ Function|||Similarity ^@ Belongs to the GTP-binding SRP family.|||Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. http://togogenome.org/gene/747365:THENA_RS02945 ^@ http://purl.uniprot.org/uniprot/M1E6W8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/747365:THENA_RS07750 ^@ http://purl.uniprot.org/uniprot/M1E9D9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HupC/HyaC/HydC family.|||Membrane http://togogenome.org/gene/747365:THENA_RS05020 ^@ http://purl.uniprot.org/uniprot/M1E8Q5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/747365:THENA_RS09445 ^@ http://purl.uniprot.org/uniprot/M1E998 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/747365:THENA_RS02530 ^@ http://purl.uniprot.org/uniprot/M1E5A2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS03850 ^@ http://purl.uniprot.org/uniprot/M1E6Z3 ^@ Similarity ^@ Belongs to the PGI/PMI family. http://togogenome.org/gene/747365:THENA_RS00650 ^@ http://purl.uniprot.org/uniprot/M1E5M5 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/747365:THENA_RS05375 ^@ http://purl.uniprot.org/uniprot/M1E7K4 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/747365:THENA_RS05815 ^@ http://purl.uniprot.org/uniprot/M1E847 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/747365:THENA_RS06055 ^@ http://purl.uniprot.org/uniprot/M1E881 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FBPase class 1 family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS08935 ^@ http://purl.uniprot.org/uniprot/M1E7Q5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/747365:THENA_RS01475 ^@ http://purl.uniprot.org/uniprot/M1E6D3 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/747365:THENA_RS00260 ^@ http://purl.uniprot.org/uniprot/M1E5F1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Belongs to the peroxiredoxin family. Prx6 subfamily.|||Cytoplasm|||Homodecamer. Pentamer of dimers that assemble into a ring structure.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/747365:THENA_RS02075 ^@ http://purl.uniprot.org/uniprot/M1E4D8 ^@ Similarity ^@ Belongs to the transposase IS21/IS408/IS1162 family. http://togogenome.org/gene/747365:THENA_RS08055 ^@ http://purl.uniprot.org/uniprot/M1E5M7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS06880 ^@ http://purl.uniprot.org/uniprot/M1E8I3 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS02620 ^@ http://purl.uniprot.org/uniprot/M1E7V4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/747365:THENA_RS06125 ^@ http://purl.uniprot.org/uniprot/M1E929 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS03670 ^@ http://purl.uniprot.org/uniprot/M1E6X4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/747365:THENA_RS08630 ^@ http://purl.uniprot.org/uniprot/M1E8Q9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/747365:THENA_RS07445 ^@ http://purl.uniprot.org/uniprot/M1E8A3 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/747365:THENA_RS04350 ^@ http://purl.uniprot.org/uniprot/M1E747 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS08465 ^@ http://purl.uniprot.org/uniprot/M1E916 ^@ Function ^@ Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/747365:THENA_RS03020 ^@ http://purl.uniprot.org/uniprot/M1E5F5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/747365:THENA_RS07700 ^@ http://purl.uniprot.org/uniprot/M1E9D6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS01325 ^@ http://purl.uniprot.org/uniprot/M1E6B5 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/747365:THENA_RS09330 ^@ http://purl.uniprot.org/uniprot/M1E9K5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/747365:THENA_RS07050 ^@ http://purl.uniprot.org/uniprot/M1E5C5 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/747365:THENA_RS03470 ^@ http://purl.uniprot.org/uniprot/M1E6V5 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/747365:THENA_RS05875 ^@ http://purl.uniprot.org/uniprot/M1E528 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/747365:THENA_RS08285 ^@ http://purl.uniprot.org/uniprot/M1E8L2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ferredoxin thioredoxin reductase beta subunit family.|||Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.|||Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin. http://togogenome.org/gene/747365:THENA_RS05920 ^@ http://purl.uniprot.org/uniprot/M1E6F5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS08980 ^@ http://purl.uniprot.org/uniprot/M1E963 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS05300 ^@ http://purl.uniprot.org/uniprot/M1E7X8 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/747365:THENA_RS00920 ^@ http://purl.uniprot.org/uniprot/M1E4Y1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Membrane http://togogenome.org/gene/747365:THENA_RS02415 ^@ http://purl.uniprot.org/uniprot/M1E6D8 ^@ Similarity ^@ Belongs to the XseB family. http://togogenome.org/gene/747365:THENA_RS04940 ^@ http://purl.uniprot.org/uniprot/M1E7D1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/747365:THENA_RS04240 ^@ http://purl.uniprot.org/uniprot/M1E4R9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS04190 ^@ http://purl.uniprot.org/uniprot/M1E8F9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/747365:THENA_RS02785 ^@ http://purl.uniprot.org/uniprot/M1E6U4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/747365:THENA_RS03615 ^@ http://purl.uniprot.org/uniprot/M1E4N9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS01120 ^@ http://purl.uniprot.org/uniprot/M1E4Z4 ^@ Similarity ^@ Belongs to the MEMO1 family. http://togogenome.org/gene/747365:THENA_RS08690 ^@ http://purl.uniprot.org/uniprot/M1E9H9 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/747365:THENA_RS00700 ^@ http://purl.uniprot.org/uniprot/M1E481 ^@ Function|||Similarity ^@ Belongs to the desulfoferrodoxin family.|||Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity. http://togogenome.org/gene/747365:THENA_RS03015 ^@ http://purl.uniprot.org/uniprot/M1E6Y1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/747365:THENA_RS08915 ^@ http://purl.uniprot.org/uniprot/M1E7Q3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.|||Membrane http://togogenome.org/gene/747365:THENA_RS09740 ^@ http://purl.uniprot.org/uniprot/M1E8T9 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/747365:THENA_RS05310 ^@ http://purl.uniprot.org/uniprot/M1E4Y2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/747365:THENA_RS01640 ^@ http://purl.uniprot.org/uniprot/M1E4B9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS01010 ^@ http://purl.uniprot.org/uniprot/M1E772 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/747365:THENA_RS02550 ^@ http://purl.uniprot.org/uniprot/M1E6R1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/747365:THENA_RS03680 ^@ http://purl.uniprot.org/uniprot/M1E794 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/747365:THENA_RS05900 ^@ http://purl.uniprot.org/uniprot/M1E532 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/747365:THENA_RS04685 ^@ http://purl.uniprot.org/uniprot/M1E7N1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/747365:THENA_RS08845 ^@ http://purl.uniprot.org/uniprot/M1E8T5 ^@ Similarity ^@ Belongs to the CRISPR-associated Csm3 family. http://togogenome.org/gene/747365:THENA_RS05015 ^@ http://purl.uniprot.org/uniprot/M1E7E5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/747365:THENA_RS07530 ^@ http://purl.uniprot.org/uniprot/M1E9C9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/747365:THENA_RS03830 ^@ http://purl.uniprot.org/uniprot/M1E8C2 ^@ Caution|||Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/747365:THENA_RS04025 ^@ http://purl.uniprot.org/uniprot/M1E5Q8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS00300 ^@ http://purl.uniprot.org/uniprot/M1E4Q6 ^@ Function ^@ Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/747365:THENA_RS09435 ^@ http://purl.uniprot.org/uniprot/M1E8Y3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/747365:THENA_RS02610 ^@ http://purl.uniprot.org/uniprot/M1E4H1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/747365:THENA_RS05890 ^@ http://purl.uniprot.org/uniprot/M1E857 ^@ Function ^@ The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. http://togogenome.org/gene/747365:THENA_RS00585 ^@ http://purl.uniprot.org/uniprot/M1E5W7 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/747365:THENA_RS08640 ^@ http://purl.uniprot.org/uniprot/M1E928 ^@ Similarity ^@ Belongs to the bacterial flagellin family. http://togogenome.org/gene/747365:THENA_RS03115 ^@ http://purl.uniprot.org/uniprot/M1E6Z8 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/747365:THENA_RS04780 ^@ http://purl.uniprot.org/uniprot/M1E5Z1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/747365:THENA_RS01525 ^@ http://purl.uniprot.org/uniprot/M1E616 ^@ Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 2 family. http://togogenome.org/gene/747365:THENA_RS05825 ^@ http://purl.uniprot.org/uniprot/M1E523 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS06105 ^@ http://purl.uniprot.org/uniprot/M1E887 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/747365:THENA_RS01435 ^@ http://purl.uniprot.org/uniprot/M1E4B1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/747365:THENA_RS00335 ^@ http://purl.uniprot.org/uniprot/M1E5G6 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/747365:THENA_RS05435 ^@ http://purl.uniprot.org/uniprot/M1E8V2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/747365:THENA_RS08910 ^@ http://purl.uniprot.org/uniprot/M1E957 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.|||Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/747365:THENA_RS00495 ^@ http://purl.uniprot.org/uniprot/M1E6V8 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/747365:THENA_RS00230 ^@ http://purl.uniprot.org/uniprot/M1E435 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/747365:THENA_RS07060 ^@ http://purl.uniprot.org/uniprot/M1E866 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/747365:THENA_RS03720 ^@ http://purl.uniprot.org/uniprot/M1E4P4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS06355 ^@ http://purl.uniprot.org/uniprot/M1E571 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/747365:THENA_RS06765 ^@ http://purl.uniprot.org/uniprot/M1E5A1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/747365:THENA_RS01155 ^@ http://purl.uniprot.org/uniprot/M1E5X2 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine. http://togogenome.org/gene/747365:THENA_RS00030 ^@ http://purl.uniprot.org/uniprot/M1E6K6 ^@ Similarity ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. http://togogenome.org/gene/747365:THENA_RS09350 ^@ http://purl.uniprot.org/uniprot/M1E8X6 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/747365:THENA_RS03365 ^@ http://purl.uniprot.org/uniprot/M1E4M3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS03120 ^@ http://purl.uniprot.org/uniprot/M1E5G5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS00775 ^@ http://purl.uniprot.org/uniprot/M1E484 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase Y family.|||Cell membrane|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/747365:THENA_RS05305 ^@ http://purl.uniprot.org/uniprot/M1E675 ^@ Similarity ^@ In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/747365:THENA_RS04090 ^@ http://purl.uniprot.org/uniprot/M1E8E8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS01380 ^@ http://purl.uniprot.org/uniprot/M1E511 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/747365:THENA_RS05545 ^@ http://purl.uniprot.org/uniprot/M1E8X0 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/747365:THENA_RS03815 ^@ http://purl.uniprot.org/uniprot/M1E5P0 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/747365:THENA_RS01530 ^@ http://purl.uniprot.org/uniprot/M1E6D7 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/747365:THENA_RS09110 ^@ http://purl.uniprot.org/uniprot/M1E7S5 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/747365:THENA_RS02465 ^@ http://purl.uniprot.org/uniprot/M1E6E4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/747365:THENA_RS04865 ^@ http://purl.uniprot.org/uniprot/M1E7B8 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/747365:THENA_RS05705 ^@ http://purl.uniprot.org/uniprot/M1E834 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/747365:THENA_RS06330 ^@ http://purl.uniprot.org/uniprot/M1E569 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/747365:THENA_RS03940 ^@ http://purl.uniprot.org/uniprot/M1E8D3 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.