http://togogenome.org/gene/745776:DGO_RS08855 ^@ http://purl.uniprot.org/uniprot/H8GWC3 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/745776:DGO_RS05985 ^@ http://purl.uniprot.org/uniprot/H8GRQ5 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/745776:DGO_RS05775 ^@ http://purl.uniprot.org/uniprot/H8GZU6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/745776:DGO_RS01370 ^@ http://purl.uniprot.org/uniprot/H8GU55 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS08595 ^@ http://purl.uniprot.org/uniprot/H8GVR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS11180 ^@ http://purl.uniprot.org/uniprot/H8GZ28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/745776:DGO_RS17710 ^@ http://purl.uniprot.org/uniprot/H8H1Q7 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Periplasm http://togogenome.org/gene/745776:DGO_RS13720 ^@ http://purl.uniprot.org/uniprot/H8GTZ3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/745776:DGO_RS00725 ^@ http://purl.uniprot.org/uniprot/H8GTB7 ^@ Similarity ^@ Belongs to the DinB family. http://togogenome.org/gene/745776:DGO_RS14555 ^@ http://purl.uniprot.org/uniprot/H8GVB4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/745776:DGO_RS16045 ^@ http://purl.uniprot.org/uniprot/H8H169 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/745776:DGO_RS10260 ^@ http://purl.uniprot.org/uniprot/H8GY36 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/745776:DGO_RS15755 ^@ http://purl.uniprot.org/uniprot/H8H111 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/745776:DGO_RS02325 ^@ http://purl.uniprot.org/uniprot/H8GW23 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/745776:DGO_RS10290 ^@ http://purl.uniprot.org/uniprot/H8GY42 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/745776:DGO_RS08985 ^@ http://purl.uniprot.org/uniprot/H8GWF1 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/745776:DGO_RS12960 ^@ http://purl.uniprot.org/uniprot/H8GT37 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/745776:DGO_RS00815 ^@ http://purl.uniprot.org/uniprot/H8GTD5 ^@ Function|||Similarity ^@ Belongs to the KptA/TPT1 family.|||Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase. http://togogenome.org/gene/745776:DGO_RS10810 ^@ http://purl.uniprot.org/uniprot/H8GYM6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS01860 ^@ http://purl.uniprot.org/uniprot/H8GVB8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS03830 ^@ http://purl.uniprot.org/uniprot/H8GXM6 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.|||Binds 2 nickel ions per subunit.|||Carbamylation allows a single lysine to coordinate two nickel ions.|||Carboxylation allows a single lysine to coordinate two nickel ions.|||Cytoplasm|||Heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. http://togogenome.org/gene/745776:DGO_RS07535 ^@ http://purl.uniprot.org/uniprot/H8GU86 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/745776:DGO_RS04285 ^@ http://purl.uniprot.org/uniprot/H8GYB9 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS01805 ^@ http://purl.uniprot.org/uniprot/H8GUV2 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/745776:DGO_RS06710 ^@ http://purl.uniprot.org/uniprot/H8GSV8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS05265 ^@ http://purl.uniprot.org/uniprot/H8GZB6 ^@ Similarity ^@ Belongs to the antibiotic N-acetyltransferase family. http://togogenome.org/gene/745776:DGO_RS07920 ^@ http://purl.uniprot.org/uniprot/H8GUX0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/745776:DGO_RS13450 ^@ http://purl.uniprot.org/uniprot/H8GTU3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/745776:DGO_RS09020 ^@ http://purl.uniprot.org/uniprot/H8GWF8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS20545 ^@ http://purl.uniprot.org/uniprot/H8H3S9 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/745776:DGO_RS16665 ^@ http://purl.uniprot.org/uniprot/H8H0H0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NlpA lipoprotein family.|||Membrane http://togogenome.org/gene/745776:DGO_RS13100 ^@ http://purl.uniprot.org/uniprot/H8GT65 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/745776:DGO_RS14730 ^@ http://purl.uniprot.org/uniprot/H8GVV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/745776:DGO_RS07950 ^@ http://purl.uniprot.org/uniprot/H8GUX8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/745776:DGO_RS02235 ^@ http://purl.uniprot.org/uniprot/H8GVJ2 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. http://togogenome.org/gene/745776:DGO_RS09050 ^@ http://purl.uniprot.org/uniprot/H8GWG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS06480 ^@ http://purl.uniprot.org/uniprot/H8GSC5 ^@ Cofactor ^@ Can also use Mn(2+) ion. http://togogenome.org/gene/745776:DGO_RS13120 ^@ http://purl.uniprot.org/uniprot/H8GT69 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS04645 ^@ http://purl.uniprot.org/uniprot/H8GYR6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.|||Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/745776:DGO_RS13600 ^@ http://purl.uniprot.org/uniprot/H8GTX1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/745776:DGO_RS00410 ^@ http://purl.uniprot.org/uniprot/H8GSQ1 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/745776:DGO_RS11925 ^@ http://purl.uniprot.org/uniprot/H8GZY2 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/745776:DGO_RS03180 ^@ http://purl.uniprot.org/uniprot/H8GX20 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/745776:DGO_RS13050 ^@ http://purl.uniprot.org/uniprot/H8GT55 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/745776:DGO_RS01070 ^@ http://purl.uniprot.org/uniprot/H8GTI7 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/745776:DGO_RS03260 ^@ http://purl.uniprot.org/uniprot/H8GX35 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/745776:DGO_RS18170 ^@ http://purl.uniprot.org/uniprot/H8H220 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0394 family.|||Membrane http://togogenome.org/gene/745776:DGO_RS03865 ^@ http://purl.uniprot.org/uniprot/H8GXW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS06345 ^@ http://purl.uniprot.org/uniprot/H8GSA0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 15 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/745776:DGO_RS14515 ^@ http://purl.uniprot.org/uniprot/H8GVA6 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/745776:DGO_RS09335 ^@ http://purl.uniprot.org/uniprot/H8GWW6 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS02175 ^@ http://purl.uniprot.org/uniprot/H8GVH9 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/745776:DGO_RS11320 ^@ http://purl.uniprot.org/uniprot/H8GZ55 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/745776:DGO_RS01455 ^@ http://purl.uniprot.org/uniprot/H8GU72 ^@ Function|||Similarity ^@ Belongs to the V-ATPase V0D/AC39 subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/745776:DGO_RS02695 ^@ http://purl.uniprot.org/uniprot/H8GWJ6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/745776:DGO_RS19550 ^@ http://purl.uniprot.org/uniprot/H8H312 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS15820 ^@ http://purl.uniprot.org/uniprot/H8H125 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein SsuA/TauA family.|||Periplasm http://togogenome.org/gene/745776:DGO_RS11620 ^@ http://purl.uniprot.org/uniprot/H8GZJ4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/745776:DGO_RS16360 ^@ http://purl.uniprot.org/uniprot/H8H0A7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/745776:DGO_RS07080 ^@ http://purl.uniprot.org/uniprot/H8GTJ0 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/745776:DGO_RS13645 ^@ http://purl.uniprot.org/uniprot/H8GTY0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS00920 ^@ http://purl.uniprot.org/uniprot/H8GTF6 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS14845 ^@ http://purl.uniprot.org/uniprot/H8GVY2 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/745776:DGO_RS11095 ^@ http://purl.uniprot.org/uniprot/H8GZ12 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS09750 ^@ http://purl.uniprot.org/uniprot/H8GXC7 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS01600 ^@ http://purl.uniprot.org/uniprot/H8GUR0 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/745776:DGO_RS13030 ^@ http://purl.uniprot.org/uniprot/H8GT51 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/745776:DGO_RS09310 ^@ http://purl.uniprot.org/uniprot/H8GWW1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS16580 ^@ http://purl.uniprot.org/uniprot/H8H0F1 ^@ Function|||Similarity ^@ Belongs to the NanE family.|||Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P). http://togogenome.org/gene/745776:DGO_RS14755 ^@ http://purl.uniprot.org/uniprot/H8GVW4 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/745776:DGO_RS08460 ^@ http://purl.uniprot.org/uniprot/H8GVN3 ^@ Similarity ^@ Belongs to the ComB family. http://togogenome.org/gene/745776:DGO_RS02305 ^@ http://purl.uniprot.org/uniprot/H8GW19 ^@ Similarity ^@ Belongs to the 6-phosphogluconate dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS10750 ^@ http://purl.uniprot.org/uniprot/H8GYL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.|||Mitochondrion http://togogenome.org/gene/745776:DGO_RS09315 ^@ http://purl.uniprot.org/uniprot/H8GWW2 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS05245 ^@ http://purl.uniprot.org/uniprot/H8GZB3 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/745776:DGO_RS10730 ^@ http://purl.uniprot.org/uniprot/H8GYL0 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/745776:DGO_RS16530 ^@ http://purl.uniprot.org/uniprot/H8H0E1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/745776:DGO_RS15470 ^@ http://purl.uniprot.org/uniprot/H8H0V1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS17735 ^@ http://purl.uniprot.org/uniprot/H8H1R3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the CRISPR-associated exonuclease Cas4 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).|||Mg(2+) or Mn(2+) required for ssDNA cleavage activity. http://togogenome.org/gene/745776:DGO_RS12440 ^@ http://purl.uniprot.org/uniprot/H8GS00 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS12930 ^@ http://purl.uniprot.org/uniprot/H8GSM3 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/745776:DGO_RS02265 ^@ http://purl.uniprot.org/uniprot/H8GW11 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS07475 ^@ http://purl.uniprot.org/uniprot/H8GTR9 ^@ Similarity ^@ In the N-terminal section; belongs to the phytochrome family. http://togogenome.org/gene/745776:DGO_RS06845 ^@ http://purl.uniprot.org/uniprot/H8GSY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS16050 ^@ http://purl.uniprot.org/uniprot/H8H170 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. http://togogenome.org/gene/745776:DGO_RS02570 ^@ http://purl.uniprot.org/uniprot/H8GW74 ^@ Function|||Similarity ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily. http://togogenome.org/gene/745776:DGO_RS12660 ^@ http://purl.uniprot.org/uniprot/H8GSH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS11245 ^@ http://purl.uniprot.org/uniprot/H8GZ41 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/745776:DGO_RS00845 ^@ http://purl.uniprot.org/uniprot/H8GTE1 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/745776:DGO_RS00665 ^@ http://purl.uniprot.org/uniprot/H8GSU9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/745776:DGO_RS07090 ^@ http://purl.uniprot.org/uniprot/H8GTJ2 ^@ Cofactor ^@ The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/745776:DGO_RS04555 ^@ http://purl.uniprot.org/uniprot/H8GYH2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS01655 ^@ http://purl.uniprot.org/uniprot/H8GUS1 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/745776:DGO_RS00795 ^@ http://purl.uniprot.org/uniprot/H8GTD1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB). http://togogenome.org/gene/745776:DGO_RS14665 ^@ http://purl.uniprot.org/uniprot/H8GVU6 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/745776:DGO_RS15780 ^@ http://purl.uniprot.org/uniprot/H8H116 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbsD / FucU family. RbsD subfamily.|||Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.|||Cytoplasm|||Homodecamer. http://togogenome.org/gene/745776:DGO_RS11540 ^@ http://purl.uniprot.org/uniprot/H8GZH8 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS15270 ^@ http://purl.uniprot.org/uniprot/H8H0R2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS13035 ^@ http://purl.uniprot.org/uniprot/H8GT52 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/745776:DGO_RS14300 ^@ http://purl.uniprot.org/uniprot/H8GV63 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS09380 ^@ http://purl.uniprot.org/uniprot/H8GWX5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS13480 ^@ http://purl.uniprot.org/uniprot/H8GTU8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/745776:DGO_RS12755 ^@ http://purl.uniprot.org/uniprot/H8GSJ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/745776:DGO_RS13855 ^@ http://purl.uniprot.org/uniprot/H8GUH4 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS18175 ^@ http://purl.uniprot.org/uniprot/H8H221 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS08020 ^@ http://purl.uniprot.org/uniprot/H8GUZ1 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/745776:DGO_RS05600 ^@ http://purl.uniprot.org/uniprot/H8GZR3 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/745776:DGO_RS16215 ^@ http://purl.uniprot.org/uniprot/H8H069 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 42 family. http://togogenome.org/gene/745776:DGO_RS06775 ^@ http://purl.uniprot.org/uniprot/H8GSX2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS13205 ^@ http://purl.uniprot.org/uniprot/H8GT86 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/745776:DGO_RS03395 ^@ http://purl.uniprot.org/uniprot/H8GX63 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS07365 ^@ http://purl.uniprot.org/uniprot/H8GTP7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS05075 ^@ http://purl.uniprot.org/uniprot/H8GZ80 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/745776:DGO_RS15350 ^@ http://purl.uniprot.org/uniprot/H8H0S7 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.|||Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.|||Homodimer.|||Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. http://togogenome.org/gene/745776:DGO_RS17750 ^@ http://purl.uniprot.org/uniprot/H8H1R7 ^@ Function ^@ CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/745776:DGO_RS01640 ^@ http://purl.uniprot.org/uniprot/H8GUR8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/745776:DGO_RS02395 ^@ http://purl.uniprot.org/uniprot/H8GW37 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/745776:DGO_RS11500 ^@ http://purl.uniprot.org/uniprot/H8GZH0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS11630 ^@ http://purl.uniprot.org/uniprot/H8GZJ6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/745776:DGO_RS16195 ^@ http://purl.uniprot.org/uniprot/H8H065 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.|||Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Carboxylation allows a single lysine to coordinate two zinc ions.|||Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Homotetramer. http://togogenome.org/gene/745776:DGO_RS02595 ^@ http://purl.uniprot.org/uniprot/H8GW79 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS12715 ^@ http://purl.uniprot.org/uniprot/H8GSI2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/745776:DGO_RS13000 ^@ http://purl.uniprot.org/uniprot/H8GT45 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/745776:DGO_RS07615 ^@ http://purl.uniprot.org/uniprot/H8GUA1 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/745776:DGO_RS11080 ^@ http://purl.uniprot.org/uniprot/H8GZ09 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/745776:DGO_RS13335 ^@ http://purl.uniprot.org/uniprot/H8GTS0 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/745776:DGO_RS07585 ^@ http://purl.uniprot.org/uniprot/H8GU95 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS03825 ^@ http://purl.uniprot.org/uniprot/H8GXM5 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/745776:DGO_RS06735 ^@ http://purl.uniprot.org/uniprot/H8GSW3 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/745776:DGO_RS04065 ^@ http://purl.uniprot.org/uniprot/H8GY00 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/745776:DGO_RS00010 ^@ http://purl.uniprot.org/uniprot/H8GS34 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/745776:DGO_RS03860 ^@ http://purl.uniprot.org/uniprot/H8GXW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS15945 ^@ http://purl.uniprot.org/uniprot/H8H149 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/745776:DGO_RS00575 ^@ http://purl.uniprot.org/uniprot/H8GST1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/745776:DGO_RS00370 ^@ http://purl.uniprot.org/uniprot/H8GSP3 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/745776:DGO_RS13310 ^@ http://purl.uniprot.org/uniprot/H8GTA3 ^@ Similarity ^@ Belongs to the mannitol dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS12480 ^@ http://purl.uniprot.org/uniprot/H8GS08 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/745776:DGO_RS15370 ^@ http://purl.uniprot.org/uniprot/H8H0T1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS09240 ^@ http://purl.uniprot.org/uniprot/H8GWU7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/745776:DGO_RS04970 ^@ http://purl.uniprot.org/uniprot/H8GYY0 ^@ Similarity ^@ Belongs to the barstar family. http://togogenome.org/gene/745776:DGO_RS04295 ^@ http://purl.uniprot.org/uniprot/H8GYC1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/745776:DGO_RS07165 ^@ http://purl.uniprot.org/uniprot/H8GTK6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/745776:DGO_RS06285 ^@ http://purl.uniprot.org/uniprot/H8GS89 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/745776:DGO_RS13860 ^@ http://purl.uniprot.org/uniprot/H8GUH5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/745776:DGO_RS01500 ^@ http://purl.uniprot.org/uniprot/H8GUP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS05950 ^@ http://purl.uniprot.org/uniprot/H8GRP8 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS13525 ^@ http://purl.uniprot.org/uniprot/H8GTV6 ^@ Similarity ^@ Belongs to the NAPRTase family. http://togogenome.org/gene/745776:DGO_RS02990 ^@ http://purl.uniprot.org/uniprot/H8GWQ2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS13535 ^@ http://purl.uniprot.org/uniprot/H8GTV8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS12360 ^@ http://purl.uniprot.org/uniprot/H8GRY3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS07625 ^@ http://purl.uniprot.org/uniprot/H8GUA3 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/745776:DGO_RS13245 ^@ http://purl.uniprot.org/uniprot/H8GT93 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/745776:DGO_RS14720 ^@ http://purl.uniprot.org/uniprot/H8GVV7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/745776:DGO_RS11335 ^@ http://purl.uniprot.org/uniprot/H8GZ58 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/745776:DGO_RS13090 ^@ http://purl.uniprot.org/uniprot/H8GT63 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/745776:DGO_RS05475 ^@ http://purl.uniprot.org/uniprot/H8GZN8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/745776:DGO_RS05140 ^@ http://purl.uniprot.org/uniprot/H8GZ93 ^@ Similarity ^@ Belongs to the RelA/SpoT family. http://togogenome.org/gene/745776:DGO_RS03840 ^@ http://purl.uniprot.org/uniprot/H8GXV6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.|||Cytoplasm|||Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.|||Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/745776:DGO_RS12965 ^@ http://purl.uniprot.org/uniprot/H8GT38 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/745776:DGO_RS04365 ^@ http://purl.uniprot.org/uniprot/H8GYD5 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/745776:DGO_RS15375 ^@ http://purl.uniprot.org/uniprot/H8H0T2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS06620 ^@ http://purl.uniprot.org/uniprot/H8GSF2 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/745776:DGO_RS07650 ^@ http://purl.uniprot.org/uniprot/H8GUA8 ^@ Function|||Similarity ^@ Belongs to the RapZ-like family.|||Displays ATPase and GTPase activities. http://togogenome.org/gene/745776:DGO_RS07160 ^@ http://purl.uniprot.org/uniprot/H8GTK5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS01225 ^@ http://purl.uniprot.org/uniprot/H8GU26 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/745776:DGO_RS07590 ^@ http://purl.uniprot.org/uniprot/H8GU96 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PEPCase type 1 family.|||Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.|||Homotetramer. http://togogenome.org/gene/745776:DGO_RS04320 ^@ http://purl.uniprot.org/uniprot/H8GYC6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/745776:DGO_RS08050 ^@ http://purl.uniprot.org/uniprot/H8GUZ7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS18395 ^@ http://purl.uniprot.org/uniprot/H8H271 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS13075 ^@ http://purl.uniprot.org/uniprot/H8GT60 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/745776:DGO_RS02425 ^@ http://purl.uniprot.org/uniprot/H8GW45 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/745776:DGO_RS14925 ^@ http://purl.uniprot.org/uniprot/H8GVZ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/745776:DGO_RS06370 ^@ http://purl.uniprot.org/uniprot/H8GSA5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the complex I 75 kDa subunit family.|||Binds 1 [2Fe-2S] cluster per subunit.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/745776:DGO_RS06985 ^@ http://purl.uniprot.org/uniprot/H8GT15 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/745776:DGO_RS08535 ^@ http://purl.uniprot.org/uniprot/H8GVP8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/745776:DGO_RS16675 ^@ http://purl.uniprot.org/uniprot/H8H0H2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS10145 ^@ http://purl.uniprot.org/uniprot/H8GXT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmC/CycZ/HelC family.|||Membrane http://togogenome.org/gene/745776:DGO_RS09230 ^@ http://purl.uniprot.org/uniprot/H8GWU5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArsB family.|||Cell membrane|||Involved in arsenical resistance. Thought to form the channel of an arsenite pump.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/745776:DGO_RS10915 ^@ http://purl.uniprot.org/uniprot/H8GYP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS02025 ^@ http://purl.uniprot.org/uniprot/H8GVF1 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/745776:DGO_RS02875 ^@ http://purl.uniprot.org/uniprot/H8GWM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS14130 ^@ http://purl.uniprot.org/uniprot/H8GUM5 ^@ Similarity ^@ Belongs to the HsdR family. http://togogenome.org/gene/745776:DGO_RS05285 ^@ http://purl.uniprot.org/uniprot/H8GZC0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/745776:DGO_RS12910 ^@ http://purl.uniprot.org/uniprot/H8GSM1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/745776:DGO_RS00740 ^@ http://purl.uniprot.org/uniprot/H8GTC0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS15875 ^@ http://purl.uniprot.org/uniprot/H8H136 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/745776:DGO_RS04545 ^@ http://purl.uniprot.org/uniprot/H8GYH0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/745776:DGO_RS02190 ^@ http://purl.uniprot.org/uniprot/H8GVI2 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/745776:DGO_RS13985 ^@ http://purl.uniprot.org/uniprot/H8GUJ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS03565 ^@ http://purl.uniprot.org/uniprot/H8GXI1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/745776:DGO_RS14405 ^@ http://purl.uniprot.org/uniprot/H8GV85 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS04790 ^@ http://purl.uniprot.org/uniprot/H8GYU4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of glycine to tRNA(Gly).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/745776:DGO_RS20960 ^@ http://purl.uniprot.org/uniprot/H8GXI9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family. http://togogenome.org/gene/745776:DGO_RS06380 ^@ http://purl.uniprot.org/uniprot/H8GSA7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/745776:DGO_RS13055 ^@ http://purl.uniprot.org/uniprot/H8GT56 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/745776:DGO_RS16515 ^@ http://purl.uniprot.org/uniprot/H8H0D8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS16095 ^@ http://purl.uniprot.org/uniprot/H8H046 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/745776:DGO_RS12285 ^@ http://purl.uniprot.org/uniprot/H8GRX2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/745776:DGO_RS00170 ^@ http://purl.uniprot.org/uniprot/H8GS67 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. http://togogenome.org/gene/745776:DGO_RS04510 ^@ http://purl.uniprot.org/uniprot/H8GYG3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/745776:DGO_RS02005 ^@ http://purl.uniprot.org/uniprot/H8GVE8 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/745776:DGO_RS09110 ^@ http://purl.uniprot.org/uniprot/H8GWS0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS00530 ^@ http://purl.uniprot.org/uniprot/H8GSS5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/745776:DGO_RS13025 ^@ http://purl.uniprot.org/uniprot/H8GT50 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/745776:DGO_RS15405 ^@ http://purl.uniprot.org/uniprot/H8H0T8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/745776:DGO_RS00435 ^@ http://purl.uniprot.org/uniprot/H8GSQ6 ^@ Function|||Similarity ^@ Belongs to the BCKDHA family.|||The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/745776:DGO_RS08955 ^@ http://purl.uniprot.org/uniprot/H8GWE5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/745776:DGO_RS12985 ^@ http://purl.uniprot.org/uniprot/H8GT42 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/745776:DGO_RS05525 ^@ http://purl.uniprot.org/uniprot/H8GZP8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/745776:DGO_RS04535 ^@ http://purl.uniprot.org/uniprot/H8GYG8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C15 family.|||Cytoplasm|||Removes 5-oxoproline from various penultimate amino acid residues except L-proline. http://togogenome.org/gene/745776:DGO_RS02575 ^@ http://purl.uniprot.org/uniprot/H8GW75 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/745776:DGO_RS11905 ^@ http://purl.uniprot.org/uniprot/H8GZX8 ^@ Cofactor ^@ Binds 1 FAD per subunit. http://togogenome.org/gene/745776:DGO_RS09185 ^@ http://purl.uniprot.org/uniprot/H8GWT6 ^@ Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/745776:DGO_RS14920 ^@ http://purl.uniprot.org/uniprot/H8GVZ7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/745776:DGO_RS05490 ^@ http://purl.uniprot.org/uniprot/H8GZP1 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/745776:DGO_RS20030 ^@ http://purl.uniprot.org/uniprot/H8H3D6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS06090 ^@ http://purl.uniprot.org/uniprot/H8GRS6 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/745776:DGO_RS14175 ^@ http://purl.uniprot.org/uniprot/H8GV42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS03480 ^@ http://purl.uniprot.org/uniprot/H8GXG0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/745776:DGO_RS02705 ^@ http://purl.uniprot.org/uniprot/H8GWJ8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 2 lipoyl cofactors covalently.|||Forms a 24-polypeptide structural core with octahedral symmetry.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/745776:DGO_RS07810 ^@ http://purl.uniprot.org/uniprot/H8GUE1 ^@ Similarity ^@ Belongs to the RimK family. LysX subfamily. http://togogenome.org/gene/745776:DGO_RS11870 ^@ http://purl.uniprot.org/uniprot/H8GZX0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS02730 ^@ http://purl.uniprot.org/uniprot/H8GWK2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS09225 ^@ http://purl.uniprot.org/uniprot/H8GWU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS01340 ^@ http://purl.uniprot.org/uniprot/H8GU49 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/745776:DGO_RS14915 ^@ http://purl.uniprot.org/uniprot/H8GVZ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/745776:DGO_RS13390 ^@ http://purl.uniprot.org/uniprot/H8GTT1 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/745776:DGO_RS13330 ^@ http://purl.uniprot.org/uniprot/H8GTA7 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS01445 ^@ http://purl.uniprot.org/uniprot/H8GU70 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS01045 ^@ http://purl.uniprot.org/uniprot/H8GTI1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/745776:DGO_RS06300 ^@ http://purl.uniprot.org/uniprot/H8GS92 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/745776:DGO_RS12935 ^@ http://purl.uniprot.org/uniprot/H8GT33 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/745776:DGO_RS03485 ^@ http://purl.uniprot.org/uniprot/H8GXG1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/745776:DGO_RS14180 ^@ http://purl.uniprot.org/uniprot/H8GV43 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/745776:DGO_RS16330 ^@ http://purl.uniprot.org/uniprot/H8H0A1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS01450 ^@ http://purl.uniprot.org/uniprot/H8GU71 ^@ Function|||Similarity ^@ Belongs to the V-ATPase E subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/745776:DGO_RS13530 ^@ http://purl.uniprot.org/uniprot/H8GTV7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/745776:DGO_RS00270 ^@ http://purl.uniprot.org/uniprot/H8GSM6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS13080 ^@ http://purl.uniprot.org/uniprot/H8GT61 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/745776:DGO_RS06355 ^@ http://purl.uniprot.org/uniprot/H8GSA2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 15 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/745776:DGO_RS06830 ^@ http://purl.uniprot.org/uniprot/H8GSY3 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/745776:DGO_RS09450 ^@ http://purl.uniprot.org/uniprot/H8GWY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetokinase family.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS13715 ^@ http://purl.uniprot.org/uniprot/H8GTZ2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS13140 ^@ http://purl.uniprot.org/uniprot/H8GT73 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/745776:DGO_RS04860 ^@ http://purl.uniprot.org/uniprot/H8GYV9 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS10980 ^@ http://purl.uniprot.org/uniprot/H8GYR0 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/745776:DGO_RS01255 ^@ http://purl.uniprot.org/uniprot/H8GU31 ^@ Function|||Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/745776:DGO_RS12890 ^@ http://purl.uniprot.org/uniprot/H8GSL7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/745776:DGO_RS02700 ^@ http://purl.uniprot.org/uniprot/H8GWJ7 ^@ Function ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/745776:DGO_RS13520 ^@ http://purl.uniprot.org/uniprot/H8GTV5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS00340 ^@ http://purl.uniprot.org/uniprot/H8GSN7 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/745776:DGO_RS01260 ^@ http://purl.uniprot.org/uniprot/H8GU32 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/745776:DGO_RS15680 ^@ http://purl.uniprot.org/uniprot/H8H0Z4 ^@ Similarity ^@ Belongs to the manganese catalase family. http://togogenome.org/gene/745776:DGO_RS06110 ^@ http://purl.uniprot.org/uniprot/H8GRT0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/745776:DGO_RS12820 ^@ http://purl.uniprot.org/uniprot/H8GSK4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell inner membrane|||Cell membrane|||Forms a complex with MdtI.|||Membrane http://togogenome.org/gene/745776:DGO_RS14670 ^@ http://purl.uniprot.org/uniprot/H8GVU7 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/745776:DGO_RS17150 ^@ http://purl.uniprot.org/uniprot/H8H1C4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArsB family.|||Cell membrane|||Involved in arsenical resistance. Thought to form the channel of an arsenite pump.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/745776:DGO_RS14550 ^@ http://purl.uniprot.org/uniprot/H8GVB3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/745776:DGO_RS14380 ^@ http://purl.uniprot.org/uniprot/H8GV80 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS06975 ^@ http://purl.uniprot.org/uniprot/H8GT13 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/745776:DGO_RS00085 ^@ http://purl.uniprot.org/uniprot/H8GS50 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS00015 ^@ http://purl.uniprot.org/uniprot/H8GS35 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/745776:DGO_RS15000 ^@ http://purl.uniprot.org/uniprot/H8GWH4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/745776:DGO_RS14410 ^@ http://purl.uniprot.org/uniprot/H8GV86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS16670 ^@ http://purl.uniprot.org/uniprot/H8H0H1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NlpA lipoprotein family.|||Membrane http://togogenome.org/gene/745776:DGO_RS18280 ^@ http://purl.uniprot.org/uniprot/H8H245 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/745776:DGO_RS01790 ^@ http://purl.uniprot.org/uniprot/H8GUU9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Cell membrane|||Membrane|||Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. http://togogenome.org/gene/745776:DGO_RS08980 ^@ http://purl.uniprot.org/uniprot/H8GWF0 ^@ Function|||Similarity ^@ Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/745776:DGO_RS15745 ^@ http://purl.uniprot.org/uniprot/H8H108 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/745776:DGO_RS06865 ^@ http://purl.uniprot.org/uniprot/H8GSZ0 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/745776:DGO_RS07995 ^@ http://purl.uniprot.org/uniprot/H8GUY5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/745776:DGO_RS20165 ^@ http://purl.uniprot.org/uniprot/H8H3H1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/745776:DGO_RS10110 ^@ http://purl.uniprot.org/uniprot/H8GXT1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS12975 ^@ http://purl.uniprot.org/uniprot/H8GT40 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/745776:DGO_RS05520 ^@ http://purl.uniprot.org/uniprot/H8GZP7 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/745776:DGO_RS15250 ^@ http://purl.uniprot.org/uniprot/H8H0Q8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/745776:DGO_RS14680 ^@ http://purl.uniprot.org/uniprot/H8GVU9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/745776:DGO_RS04225 ^@ http://purl.uniprot.org/uniprot/H8GY28 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/745776:DGO_RS13710 ^@ http://purl.uniprot.org/uniprot/H8GTZ1 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/745776:DGO_RS07825 ^@ http://purl.uniprot.org/uniprot/H8GUE4 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/745776:DGO_RS13755 ^@ http://purl.uniprot.org/uniprot/H8GUF7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/745776:DGO_RS13125 ^@ http://purl.uniprot.org/uniprot/H8GT70 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/745776:DGO_RS00025 ^@ http://purl.uniprot.org/uniprot/H8GS37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/745776:DGO_RS15920 ^@ http://purl.uniprot.org/uniprot/H8H144 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS09810 ^@ http://purl.uniprot.org/uniprot/H8GXD9 ^@ Similarity ^@ Belongs to the peptidase S1B family. http://togogenome.org/gene/745776:DGO_RS02975 ^@ http://purl.uniprot.org/uniprot/H8GWP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NiCoT transporter (TC 2.A.52) family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS10470 ^@ http://purl.uniprot.org/uniprot/H8GY77 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/745776:DGO_RS05785 ^@ http://purl.uniprot.org/uniprot/H8GZU8 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/745776:DGO_RS12625 ^@ http://purl.uniprot.org/uniprot/H8GSG7 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/745776:DGO_RS05260 ^@ http://purl.uniprot.org/uniprot/H8GZB5 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/745776:DGO_RS06360 ^@ http://purl.uniprot.org/uniprot/H8GSA3 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/745776:DGO_RS15975 ^@ http://purl.uniprot.org/uniprot/H8H155 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Membrane http://togogenome.org/gene/745776:DGO_RS17690 ^@ http://purl.uniprot.org/uniprot/H8H1Q3 ^@ Similarity ^@ Belongs to the bacterial secretin family. http://togogenome.org/gene/745776:DGO_RS17575 ^@ http://purl.uniprot.org/uniprot/H8H1N1 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Periplasm http://togogenome.org/gene/745776:DGO_RS16355 ^@ http://purl.uniprot.org/uniprot/H8H0A6 ^@ Similarity ^@ Belongs to the DinB family. http://togogenome.org/gene/745776:DGO_RS16855 ^@ http://purl.uniprot.org/uniprot/H8H0K9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS02655 ^@ http://purl.uniprot.org/uniprot/H8GWI6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS02600 ^@ http://purl.uniprot.org/uniprot/H8GW80 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/745776:DGO_RS11860 ^@ http://purl.uniprot.org/uniprot/H8GZW8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/745776:DGO_RS11470 ^@ http://purl.uniprot.org/uniprot/H8GZG4 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/745776:DGO_RS04755 ^@ http://purl.uniprot.org/uniprot/H8GYT9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/745776:DGO_RS00155 ^@ http://purl.uniprot.org/uniprot/H8GS64 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/745776:DGO_RS08285 ^@ http://purl.uniprot.org/uniprot/H8GVJ9 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/745776:DGO_RS04235 ^@ http://purl.uniprot.org/uniprot/H8GYA9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS13045 ^@ http://purl.uniprot.org/uniprot/H8GT54 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/745776:DGO_RS11050 ^@ http://purl.uniprot.org/uniprot/H8GZ02 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/745776:DGO_RS06930 ^@ http://purl.uniprot.org/uniprot/H8GT04 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/745776:DGO_RS03305 ^@ http://purl.uniprot.org/uniprot/H8GX44 ^@ PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS05435 ^@ http://purl.uniprot.org/uniprot/H8GZF1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/745776:DGO_RS06390 ^@ http://purl.uniprot.org/uniprot/H8GSA9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/745776:DGO_RS01525 ^@ http://purl.uniprot.org/uniprot/H8GUP5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS14385 ^@ http://purl.uniprot.org/uniprot/H8GV81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/745776:DGO_RS04270 ^@ http://purl.uniprot.org/uniprot/H8GYB6 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/745776:DGO_RS05610 ^@ http://purl.uniprot.org/uniprot/H8GZR5 ^@ Similarity ^@ Belongs to the dGTPase family. Type 2 subfamily. http://togogenome.org/gene/745776:DGO_RS05765 ^@ http://purl.uniprot.org/uniprot/H8GZU4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/745776:DGO_RS02350 ^@ http://purl.uniprot.org/uniprot/H8GW28 ^@ Similarity ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. http://togogenome.org/gene/745776:DGO_RS01635 ^@ http://purl.uniprot.org/uniprot/H8GUR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS05460 ^@ http://purl.uniprot.org/uniprot/H8GZN5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/745776:DGO_RS16465 ^@ http://purl.uniprot.org/uniprot/H8H0C8 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit A family. http://togogenome.org/gene/745776:DGO_RS09235 ^@ http://purl.uniprot.org/uniprot/H8GWU6 ^@ Function|||Similarity ^@ Belongs to the RecD family. RecD-like subfamily.|||DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity. http://togogenome.org/gene/745776:DGO_RS03820 ^@ http://purl.uniprot.org/uniprot/H8GXM4 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/745776:DGO_RS07255 ^@ http://purl.uniprot.org/uniprot/H8GTM3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS05120 ^@ http://purl.uniprot.org/uniprot/H8GZ89 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/745776:DGO_RS14710 ^@ http://purl.uniprot.org/uniprot/H8GVV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/745776:DGO_RS04950 ^@ http://purl.uniprot.org/uniprot/H8GYX6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/745776:DGO_RS16590 ^@ http://purl.uniprot.org/uniprot/H8H0F2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS03835 ^@ http://purl.uniprot.org/uniprot/H8GXM7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits.|||In the C-terminal section; belongs to the urease beta subunit family.|||In the N-terminal section; belongs to the urease gamma subunit family. http://togogenome.org/gene/745776:DGO_RS01475 ^@ http://purl.uniprot.org/uniprot/H8GUN5 ^@ Function|||Similarity ^@ Belongs to the V-ATPase D subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/745776:DGO_RS03845 ^@ http://purl.uniprot.org/uniprot/H8GXV7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreD family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/745776:DGO_RS19450 ^@ http://purl.uniprot.org/uniprot/H8H2Y9 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/745776:DGO_RS10885 ^@ http://purl.uniprot.org/uniprot/H8GYP2 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/745776:DGO_RS13610 ^@ http://purl.uniprot.org/uniprot/H8GTX3 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/745776:DGO_RS08520 ^@ http://purl.uniprot.org/uniprot/H8GVP5 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/745776:DGO_RS15015 ^@ http://purl.uniprot.org/uniprot/H8GWH7 ^@ Function|||Similarity ^@ Belongs to the RNase Y family.|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/745776:DGO_RS00450 ^@ http://purl.uniprot.org/uniprot/H8GSQ9 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS16410 ^@ http://purl.uniprot.org/uniprot/H8H0B7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS17570 ^@ http://purl.uniprot.org/uniprot/H8H1N0 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Periplasm http://togogenome.org/gene/745776:DGO_RS10950 ^@ http://purl.uniprot.org/uniprot/H8GYQ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS04700 ^@ http://purl.uniprot.org/uniprot/H8GYS8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/745776:DGO_RS17660 ^@ http://purl.uniprot.org/uniprot/H8H1P9 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/745776:DGO_RS16225 ^@ http://purl.uniprot.org/uniprot/H8H071 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS14465 ^@ http://purl.uniprot.org/uniprot/H8GV97 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/745776:DGO_RS08880 ^@ http://purl.uniprot.org/uniprot/H8GWC9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/745776:DGO_RS03150 ^@ http://purl.uniprot.org/uniprot/H8GX13 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/745776:DGO_RS08840 ^@ http://purl.uniprot.org/uniprot/H8GWC0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/745776:DGO_RS05800 ^@ http://purl.uniprot.org/uniprot/H8GZV1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/745776:DGO_RS14340 ^@ http://purl.uniprot.org/uniprot/H8GV72 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/745776:DGO_RS02660 ^@ http://purl.uniprot.org/uniprot/H8GWI7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS12515 ^@ http://purl.uniprot.org/uniprot/H8GS16 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/745776:DGO_RS07240 ^@ http://purl.uniprot.org/uniprot/H8GTM0 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/745776:DGO_RS02375 ^@ http://purl.uniprot.org/uniprot/H8GW33 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/745776:DGO_RS13070 ^@ http://purl.uniprot.org/uniprot/H8GT59 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/745776:DGO_RS06130 ^@ http://purl.uniprot.org/uniprot/H8GRT3 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS07500 ^@ http://purl.uniprot.org/uniprot/H8GU78 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS12925 ^@ http://purl.uniprot.org/uniprot/H8GSM2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS06190 ^@ http://purl.uniprot.org/uniprot/H8GRU5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/745776:DGO_RS12990 ^@ http://purl.uniprot.org/uniprot/H8GT43 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/745776:DGO_RS09250 ^@ http://purl.uniprot.org/uniprot/H8GWU9 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/745776:DGO_RS11855 ^@ http://purl.uniprot.org/uniprot/H8GZW7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/745776:DGO_RS11805 ^@ http://purl.uniprot.org/uniprot/H8GZN1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidine kinase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/745776:DGO_RS01905 ^@ http://purl.uniprot.org/uniprot/H8GVC7 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/745776:DGO_RS14430 ^@ http://purl.uniprot.org/uniprot/H8GV90 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/745776:DGO_RS08000 ^@ http://purl.uniprot.org/uniprot/H8GUY7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/745776:DGO_RS11210 ^@ http://purl.uniprot.org/uniprot/H8GZ34 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/745776:DGO_RS07910 ^@ http://purl.uniprot.org/uniprot/H8GUW8 ^@ Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. http://togogenome.org/gene/745776:DGO_RS16325 ^@ http://purl.uniprot.org/uniprot/H8H0A0 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/745776:DGO_RS06365 ^@ http://purl.uniprot.org/uniprot/H8GSA4 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/745776:DGO_RS03850 ^@ http://purl.uniprot.org/uniprot/H8GXV8 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/745776:DGO_RS12270 ^@ http://purl.uniprot.org/uniprot/H8GRW9 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/745776:DGO_RS20440 ^@ http://purl.uniprot.org/uniprot/H8H3P0 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/745776:DGO_RS15175 ^@ http://purl.uniprot.org/uniprot/H8H0P3 ^@ Similarity ^@ Belongs to the CmpA/NrtA family. http://togogenome.org/gene/745776:DGO_RS14420 ^@ http://purl.uniprot.org/uniprot/H8GV88 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/745776:DGO_RS16025 ^@ http://purl.uniprot.org/uniprot/H8H165 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS12995 ^@ http://purl.uniprot.org/uniprot/H8GT44 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/745776:DGO_RS05865 ^@ http://purl.uniprot.org/uniprot/H8GRN1 ^@ Similarity ^@ Belongs to the PstS family. http://togogenome.org/gene/745776:DGO_RS15180 ^@ http://purl.uniprot.org/uniprot/H8H0P4 ^@ Function|||Similarity ^@ Belongs to the cyanase family.|||Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. http://togogenome.org/gene/745776:DGO_RS13085 ^@ http://purl.uniprot.org/uniprot/H8GT62 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/745776:DGO_RS00880 ^@ http://purl.uniprot.org/uniprot/H8GTE8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/745776:DGO_RS08250 ^@ http://purl.uniprot.org/uniprot/H8GV37 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/745776:DGO_RS06375 ^@ http://purl.uniprot.org/uniprot/H8GSA6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/745776:DGO_RS01925 ^@ http://purl.uniprot.org/uniprot/H8GVD2 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS07970 ^@ http://purl.uniprot.org/uniprot/H8GUY2 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/745776:DGO_RS05060 ^@ http://purl.uniprot.org/uniprot/H8GZ77 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/745776:DGO_RS02915 ^@ http://purl.uniprot.org/uniprot/H8GWN7 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/745776:DGO_RS14375 ^@ http://purl.uniprot.org/uniprot/H8GV79 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/745776:DGO_RS07085 ^@ http://purl.uniprot.org/uniprot/H8GTJ1 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/745776:DGO_RS12830 ^@ http://purl.uniprot.org/uniprot/H8GSK6 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/745776:DGO_RS00355 ^@ http://purl.uniprot.org/uniprot/H8GSP0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS13150 ^@ http://purl.uniprot.org/uniprot/H8GT75 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. TreS subfamily. http://togogenome.org/gene/745776:DGO_RS03585 ^@ http://purl.uniprot.org/uniprot/H8GXI5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS05685 ^@ http://purl.uniprot.org/uniprot/H8GZS9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/745776:DGO_RS11815 ^@ http://purl.uniprot.org/uniprot/H8GZV9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds the 23S rRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/745776:DGO_RS12435 ^@ http://purl.uniprot.org/uniprot/H8GRZ9 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS01440 ^@ http://purl.uniprot.org/uniprot/H8GU69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Membrane http://togogenome.org/gene/745776:DGO_RS14225 ^@ http://purl.uniprot.org/uniprot/H8GV52 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/745776:DGO_RS17700 ^@ http://purl.uniprot.org/uniprot/H8H1Q5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/745776:DGO_RS07610 ^@ http://purl.uniprot.org/uniprot/H8GUA0 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/745776:DGO_RS14195 ^@ http://purl.uniprot.org/uniprot/H8GV46 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS11650 ^@ http://purl.uniprot.org/uniprot/H8GZK0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/745776:DGO_RS13005 ^@ http://purl.uniprot.org/uniprot/H8GT46 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/745776:DGO_RS14540 ^@ http://purl.uniprot.org/uniprot/H8GVB1 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/745776:DGO_RS00335 ^@ http://purl.uniprot.org/uniprot/H8GSN6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the CobB/CobQ family.|||Involved in acetate metabolism.|||The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site. http://togogenome.org/gene/745776:DGO_RS00630 ^@ http://purl.uniprot.org/uniprot/H8GSU2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS13105 ^@ http://purl.uniprot.org/uniprot/H8GT66 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/745776:DGO_RS09445 ^@ http://purl.uniprot.org/uniprot/H8GWY8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/745776:DGO_RS06445 ^@ http://purl.uniprot.org/uniprot/H8GSB9 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/745776:DGO_RS00650 ^@ http://purl.uniprot.org/uniprot/H8GSU6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/745776:DGO_RS12005 ^@ http://purl.uniprot.org/uniprot/H8GZZ7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS16490 ^@ http://purl.uniprot.org/uniprot/H8H0D3 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/745776:DGO_RS12980 ^@ http://purl.uniprot.org/uniprot/H8GT41 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/745776:DGO_RS02565 ^@ http://purl.uniprot.org/uniprot/H8GW73 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/745776:DGO_RS10415 ^@ http://purl.uniprot.org/uniprot/H8GY66 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/745776:DGO_RS14740 ^@ http://purl.uniprot.org/uniprot/H8GVW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS06425 ^@ http://purl.uniprot.org/uniprot/H8GSB6 ^@ Similarity ^@ Belongs to the TelA family. http://togogenome.org/gene/745776:DGO_RS16560 ^@ http://purl.uniprot.org/uniprot/H8H0E7 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/745776:DGO_RS02720 ^@ http://purl.uniprot.org/uniprot/H8GWK1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/745776:DGO_RS12635 ^@ http://purl.uniprot.org/uniprot/H8GSG9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS07505 ^@ http://purl.uniprot.org/uniprot/H8GU79 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/745776:DGO_RS13895 ^@ http://purl.uniprot.org/uniprot/H8GUI2 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/745776:DGO_RS16830 ^@ http://purl.uniprot.org/uniprot/H8H0K3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS08415 ^@ http://purl.uniprot.org/uniprot/H8GVM5 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/745776:DGO_RS01740 ^@ http://purl.uniprot.org/uniprot/H8GUT9 ^@ Similarity ^@ Belongs to the aminoglycoside phosphotransferase family. http://togogenome.org/gene/745776:DGO_RS18240 ^@ http://purl.uniprot.org/uniprot/H8H237 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/745776:DGO_RS14820 ^@ http://purl.uniprot.org/uniprot/H8GVX7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS01030 ^@ http://purl.uniprot.org/uniprot/H8GTH7 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/745776:DGO_RS13495 ^@ http://purl.uniprot.org/uniprot/H8GTV0 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/745776:DGO_RS06405 ^@ http://purl.uniprot.org/uniprot/H8GSB2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/745776:DGO_RS01810 ^@ http://purl.uniprot.org/uniprot/H8GUV3 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/745776:DGO_RS19660 ^@ http://purl.uniprot.org/uniprot/H8H335 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/745776:DGO_RS02040 ^@ http://purl.uniprot.org/uniprot/H8GVF4 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/745776:DGO_RS11565 ^@ http://purl.uniprot.org/uniprot/H8GZI3 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/745776:DGO_RS03735 ^@ http://purl.uniprot.org/uniprot/H8GXK8 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/745776:DGO_RS19950 ^@ http://purl.uniprot.org/uniprot/H8H3B1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/745776:DGO_RS12470 ^@ http://purl.uniprot.org/uniprot/H8GS06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/745776:DGO_RS05795 ^@ http://purl.uniprot.org/uniprot/H8GZV0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/745776:DGO_RS07215 ^@ http://purl.uniprot.org/uniprot/H8GTL5 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily. http://togogenome.org/gene/745776:DGO_RS06890 ^@ http://purl.uniprot.org/uniprot/H8GSZ5 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/745776:DGO_RS14505 ^@ http://purl.uniprot.org/uniprot/H8GVA4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS10510 ^@ http://purl.uniprot.org/uniprot/H8GY86 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/745776:DGO_RS00200 ^@ http://purl.uniprot.org/uniprot/H8GS72 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DtxR/MntR family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/745776:DGO_RS11735 ^@ http://purl.uniprot.org/uniprot/H8GZL8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/745776:DGO_RS02645 ^@ http://purl.uniprot.org/uniprot/H8GWI4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS14310 ^@ http://purl.uniprot.org/uniprot/H8GV65 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/745776:DGO_RS11965 ^@ http://purl.uniprot.org/uniprot/H8GZY9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.|||Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/745776:DGO_RS11985 ^@ http://purl.uniprot.org/uniprot/H8GZZ3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnE family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. http://togogenome.org/gene/745776:DGO_RS17180 ^@ http://purl.uniprot.org/uniprot/H8H1D4 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/745776:DGO_RS11340 ^@ http://purl.uniprot.org/uniprot/H8GZ59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial secretin family.|||Cell outer membrane http://togogenome.org/gene/745776:DGO_RS11585 ^@ http://purl.uniprot.org/uniprot/H8GZI7 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/745776:DGO_RS12815 ^@ http://purl.uniprot.org/uniprot/H8GSK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS08095 ^@ http://purl.uniprot.org/uniprot/H8GV06 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/745776:DGO_RS08655 ^@ http://purl.uniprot.org/uniprot/H8GVS2 ^@ Similarity ^@ Belongs to the OMP decarboxylase family. Type 2 subfamily. http://togogenome.org/gene/745776:DGO_RS12580 ^@ http://purl.uniprot.org/uniprot/H8GS29 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/745776:DGO_RS11310 ^@ http://purl.uniprot.org/uniprot/H8GZ53 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/745776:DGO_RS09045 ^@ http://purl.uniprot.org/uniprot/H8GWG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS02020 ^@ http://purl.uniprot.org/uniprot/H8GVF0 ^@ Similarity ^@ Belongs to the type IB topoisomerase family. http://togogenome.org/gene/745776:DGO_RS09395 ^@ http://purl.uniprot.org/uniprot/H8GWX8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS12405 ^@ http://purl.uniprot.org/uniprot/H8GRZ2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/745776:DGO_RS16000 ^@ http://purl.uniprot.org/uniprot/H8H161 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS00720 ^@ http://purl.uniprot.org/uniprot/H8GTB6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/745776:DGO_RS13765 ^@ http://purl.uniprot.org/uniprot/H8GUF9 ^@ Similarity ^@ Belongs to the fatty acid desaturase type 2 family. http://togogenome.org/gene/745776:DGO_RS11695 ^@ http://purl.uniprot.org/uniprot/H8GZL0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/745776:DGO_RS04515 ^@ http://purl.uniprot.org/uniprot/H8GYG4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/745776:DGO_RS07870 ^@ http://purl.uniprot.org/uniprot/H8GUF3 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/745776:DGO_RS04175 ^@ http://purl.uniprot.org/uniprot/H8GY18 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS11370 ^@ http://purl.uniprot.org/uniprot/H8GZ65 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/745776:DGO_RS12510 ^@ http://purl.uniprot.org/uniprot/H8GS15 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/745776:DGO_RS01900 ^@ http://purl.uniprot.org/uniprot/H8GVC6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS10155 ^@ http://purl.uniprot.org/uniprot/H8GXU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS12520 ^@ http://purl.uniprot.org/uniprot/H8GS17 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/745776:DGO_RS14295 ^@ http://purl.uniprot.org/uniprot/H8GV62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/745776:DGO_RS10450 ^@ http://purl.uniprot.org/uniprot/H8GY73 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/745776:DGO_RS04795 ^@ http://purl.uniprot.org/uniprot/H8GYU6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS11590 ^@ http://purl.uniprot.org/uniprot/H8GZI8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS08965 ^@ http://purl.uniprot.org/uniprot/H8GWE7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS21350 ^@ http://purl.uniprot.org/uniprot/H8H1P8 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/745776:DGO_RS10815 ^@ http://purl.uniprot.org/uniprot/H8GYM7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/745776:DGO_RS01285 ^@ http://purl.uniprot.org/uniprot/H8GU37 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/745776:DGO_RS15850 ^@ http://purl.uniprot.org/uniprot/H8H131 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 42 family. http://togogenome.org/gene/745776:DGO_RS15170 ^@ http://purl.uniprot.org/uniprot/H8H0P2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS13165 ^@ http://purl.uniprot.org/uniprot/H8GT78 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/745776:DGO_RS16875 ^@ http://purl.uniprot.org/uniprot/H8H0L3 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/745776:DGO_RS14280 ^@ http://purl.uniprot.org/uniprot/H8GV59 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Binds 1 Fe cation per subunit.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/745776:DGO_RS15510 ^@ http://purl.uniprot.org/uniprot/H8H0V9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS20535 ^@ http://purl.uniprot.org/uniprot/H8H3S0 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/745776:DGO_RS05935 ^@ http://purl.uniprot.org/uniprot/H8GRP5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/745776:DGO_RS19935 ^@ http://purl.uniprot.org/uniprot/H8H3A5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS06585 ^@ http://purl.uniprot.org/uniprot/H8GSE5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/745776:DGO_RS03020 ^@ http://purl.uniprot.org/uniprot/H8GWQ9 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/745776:DGO_RS06140 ^@ http://purl.uniprot.org/uniprot/H8GRT5 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/745776:DGO_RS09255 ^@ http://purl.uniprot.org/uniprot/H8GWV0 ^@ Similarity ^@ Belongs to the ycf81 family. http://togogenome.org/gene/745776:DGO_RS12525 ^@ http://purl.uniprot.org/uniprot/H8GS18 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/745776:DGO_RS08705 ^@ http://purl.uniprot.org/uniprot/H8GW94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS16910 ^@ http://purl.uniprot.org/uniprot/H8H174 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/745776:DGO_RS12785 ^@ http://purl.uniprot.org/uniprot/H8GSJ7 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS17510 ^@ http://purl.uniprot.org/uniprot/H8H1L3 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/745776:DGO_RS13010 ^@ http://purl.uniprot.org/uniprot/H8GT47 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/745776:DGO_RS11410 ^@ http://purl.uniprot.org/uniprot/H8GZ73 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/745776:DGO_RS13145 ^@ http://purl.uniprot.org/uniprot/H8GT74 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/745776:DGO_RS06855 ^@ http://purl.uniprot.org/uniprot/H8GSY8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 42 family. http://togogenome.org/gene/745776:DGO_RS04835 ^@ http://purl.uniprot.org/uniprot/H8GYV4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/745776:DGO_RS02895 ^@ http://purl.uniprot.org/uniprot/H8GWN3 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/745776:DGO_RS05195 ^@ http://purl.uniprot.org/uniprot/H8GZA4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/745776:DGO_RS00805 ^@ http://purl.uniprot.org/uniprot/H8GTD3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M32 family.|||Binds 1 zinc ion per subunit.|||Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. http://togogenome.org/gene/745776:DGO_RS07395 ^@ http://purl.uniprot.org/uniprot/H8GTQ3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS12475 ^@ http://purl.uniprot.org/uniprot/H8GS07 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/745776:DGO_RS11895 ^@ http://purl.uniprot.org/uniprot/H8GZX6 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS15340 ^@ http://purl.uniprot.org/uniprot/H8H0S5 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/745776:DGO_RS14545 ^@ http://purl.uniprot.org/uniprot/H8GVB2 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/745776:DGO_RS19910 ^@ http://purl.uniprot.org/uniprot/H8H397 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS12350 ^@ http://purl.uniprot.org/uniprot/H8GRY1 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/745776:DGO_RS16315 ^@ http://purl.uniprot.org/uniprot/H8H098 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/745776:DGO_RS10385 ^@ http://purl.uniprot.org/uniprot/H8GY61 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/745776:DGO_RS13850 ^@ http://purl.uniprot.org/uniprot/H8GUH3 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/745776:DGO_RS02065 ^@ http://purl.uniprot.org/uniprot/H8GVF8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/745776:DGO_RS13885 ^@ http://purl.uniprot.org/uniprot/H8GUI0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/745776:DGO_RS01470 ^@ http://purl.uniprot.org/uniprot/H8GUN4 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. http://togogenome.org/gene/745776:DGO_RS04830 ^@ http://purl.uniprot.org/uniprot/H8GYV3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/745776:DGO_RS04895 ^@ http://purl.uniprot.org/uniprot/H8GYW5 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters.|||Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. http://togogenome.org/gene/745776:DGO_RS13540 ^@ http://purl.uniprot.org/uniprot/H8GTV9 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/745776:DGO_RS16275 ^@ http://purl.uniprot.org/uniprot/H8H090 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/745776:DGO_RS13385 ^@ http://purl.uniprot.org/uniprot/H8GTT0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/745776:DGO_RS06330 ^@ http://purl.uniprot.org/uniprot/H8GS97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Membrane http://togogenome.org/gene/745776:DGO_RS13400 ^@ http://purl.uniprot.org/uniprot/H8GTT3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/745776:DGO_RS05480 ^@ http://purl.uniprot.org/uniprot/H8GZN9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Homodimer. http://togogenome.org/gene/745776:DGO_RS10860 ^@ http://purl.uniprot.org/uniprot/H8GYN7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/745776:DGO_RS07210 ^@ http://purl.uniprot.org/uniprot/H8GTL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/745776:DGO_RS14255 ^@ http://purl.uniprot.org/uniprot/H8GV55 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/745776:DGO_RS16775 ^@ http://purl.uniprot.org/uniprot/H8H0J2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS15225 ^@ http://purl.uniprot.org/uniprot/H8H0Q4 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/745776:DGO_RS10490 ^@ http://purl.uniprot.org/uniprot/H8GY81 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the zinc-containing alcohol dehydrogenase family.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/745776:DGO_RS12655 ^@ http://purl.uniprot.org/uniprot/H8GSH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS04450 ^@ http://purl.uniprot.org/uniprot/H8GYF1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/745776:DGO_RS16405 ^@ http://purl.uniprot.org/uniprot/H8H0B6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS01365 ^@ http://purl.uniprot.org/uniprot/H8GU54 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS02635 ^@ http://purl.uniprot.org/uniprot/H8GW87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS00330 ^@ http://purl.uniprot.org/uniprot/H8GSN5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/745776:DGO_RS09340 ^@ http://purl.uniprot.org/uniprot/H8GWW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/745776:DGO_RS13410 ^@ http://purl.uniprot.org/uniprot/H8GTT5 ^@ Similarity ^@ Belongs to the UPF0173 family. http://togogenome.org/gene/745776:DGO_RS06605 ^@ http://purl.uniprot.org/uniprot/H8GSE9 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/745776:DGO_RS08550 ^@ http://purl.uniprot.org/uniprot/H8GVQ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/745776:DGO_RS01105 ^@ http://purl.uniprot.org/uniprot/H8GU01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS00550 ^@ http://purl.uniprot.org/uniprot/H8GSS9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS11915 ^@ http://purl.uniprot.org/uniprot/H8GZY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/745776:DGO_RS16350 ^@ http://purl.uniprot.org/uniprot/H8H0A5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/745776:DGO_RS08110 ^@ http://purl.uniprot.org/uniprot/H8GV09 ^@ Function|||Similarity ^@ Belongs to the RlpA family.|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/745776:DGO_RS12465 ^@ http://purl.uniprot.org/uniprot/H8GS05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS16815 ^@ http://purl.uniprot.org/uniprot/H8H0K0 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/745776:DGO_RS11025 ^@ http://purl.uniprot.org/uniprot/H8GYZ7 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/745776:DGO_RS00960 ^@ http://purl.uniprot.org/uniprot/H8GTG4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/745776:DGO_RS13320 ^@ http://purl.uniprot.org/uniprot/H8GTA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS02925 ^@ http://purl.uniprot.org/uniprot/H8GWN9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS05750 ^@ http://purl.uniprot.org/uniprot/H8GZU2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/745776:DGO_RS15485 ^@ http://purl.uniprot.org/uniprot/H8H0V4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/745776:DGO_RS14570 ^@ http://purl.uniprot.org/uniprot/H8GVS7 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/745776:DGO_RS16435 ^@ http://purl.uniprot.org/uniprot/H8H0C2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/745776:DGO_RS03875 ^@ http://purl.uniprot.org/uniprot/H8GXW3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/745776:DGO_RS02890 ^@ http://purl.uniprot.org/uniprot/H8GWN1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/745776:DGO_RS00840 ^@ http://purl.uniprot.org/uniprot/H8GTE0 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/745776:DGO_RS13020 ^@ http://purl.uniprot.org/uniprot/H8GT49 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/745776:DGO_RS14290 ^@ http://purl.uniprot.org/uniprot/H8GV61 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/745776:DGO_RS09065 ^@ http://purl.uniprot.org/uniprot/H8GWG7 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/745776:DGO_RS00165 ^@ http://purl.uniprot.org/uniprot/H8GS66 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/745776:DGO_RS15160 ^@ http://purl.uniprot.org/uniprot/H8H0P0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Membrane http://togogenome.org/gene/745776:DGO_RS07465 ^@ http://purl.uniprot.org/uniprot/H8GTR7 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/745776:DGO_RS15855 ^@ http://purl.uniprot.org/uniprot/H8H132 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 53 family. http://togogenome.org/gene/745776:DGO_RS07990 ^@ http://purl.uniprot.org/uniprot/H8GUY4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS10515 ^@ http://purl.uniprot.org/uniprot/H8GY87 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/745776:DGO_RS06315 ^@ http://purl.uniprot.org/uniprot/H8GS94 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/745776:DGO_RS08860 ^@ http://purl.uniprot.org/uniprot/H8GWC4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS09775 ^@ http://purl.uniprot.org/uniprot/H8GXD2 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/745776:DGO_RS19470 ^@ http://purl.uniprot.org/uniprot/H8H2Z3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NucS endonuclease family.|||Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS05810 ^@ http://purl.uniprot.org/uniprot/H8GT67 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/745776:DGO_RS07435 ^@ http://purl.uniprot.org/uniprot/H8GTR1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS12100 ^@ http://purl.uniprot.org/uniprot/H8H015 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS07425 ^@ http://purl.uniprot.org/uniprot/H8GTQ9 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/745776:DGO_RS19890 ^@ http://purl.uniprot.org/uniprot/H8H393 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/745776:DGO_RS04960 ^@ http://purl.uniprot.org/uniprot/H8GYX8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS00660 ^@ http://purl.uniprot.org/uniprot/H8GSU8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/745776:DGO_RS05570 ^@ http://purl.uniprot.org/uniprot/H8GZQ7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS10795 ^@ http://purl.uniprot.org/uniprot/H8GYM3 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/745776:DGO_RS03090 ^@ http://purl.uniprot.org/uniprot/H8GX02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS07620 ^@ http://purl.uniprot.org/uniprot/H8GUA2 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/745776:DGO_RS09425 ^@ http://purl.uniprot.org/uniprot/H8GWY4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS17960 ^@ http://purl.uniprot.org/uniprot/H8H1W8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VirD4/TraG family.|||Membrane http://togogenome.org/gene/745776:DGO_RS07830 ^@ http://purl.uniprot.org/uniprot/H8GUE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS16790 ^@ http://purl.uniprot.org/uniprot/H8H0J5 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/745776:DGO_RS02255 ^@ http://purl.uniprot.org/uniprot/H8GW09 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/745776:DGO_RS15840 ^@ http://purl.uniprot.org/uniprot/H8H129 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS13670 ^@ http://purl.uniprot.org/uniprot/H8GTY4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS02945 ^@ http://purl.uniprot.org/uniprot/H8GWP3 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/745776:DGO_RS07835 ^@ http://purl.uniprot.org/uniprot/H8GUE6 ^@ Similarity ^@ Belongs to the prephenate/arogenate dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS11940 ^@ http://purl.uniprot.org/uniprot/H8GZY6 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/745776:DGO_RS14330 ^@ http://purl.uniprot.org/uniprot/H8GV69 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/745776:DGO_RS12000 ^@ http://purl.uniprot.org/uniprot/H8GZZ6 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/745776:DGO_RS11995 ^@ http://purl.uniprot.org/uniprot/H8GZZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS12880 ^@ http://purl.uniprot.org/uniprot/H8GSL5 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/745776:DGO_RS15120 ^@ http://purl.uniprot.org/uniprot/H8H0N2 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/745776:DGO_RS04245 ^@ http://purl.uniprot.org/uniprot/H8GYB1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS13930 ^@ http://purl.uniprot.org/uniprot/H8GUI9 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/745776:DGO_RS06220 ^@ http://purl.uniprot.org/uniprot/H8GRV2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/745776:DGO_RS07095 ^@ http://purl.uniprot.org/uniprot/H8GTJ3 ^@ Cofactor ^@ The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/745776:DGO_RS09290 ^@ http://purl.uniprot.org/uniprot/H8GWV7 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/745776:DGO_RS00345 ^@ http://purl.uniprot.org/uniprot/H8GSN8 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/745776:DGO_RS10300 ^@ http://purl.uniprot.org/uniprot/H8GY44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS09210 ^@ http://purl.uniprot.org/uniprot/H8GWU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS00655 ^@ http://purl.uniprot.org/uniprot/H8GSU7 ^@ Caution|||Function ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/745776:DGO_RS08530 ^@ http://purl.uniprot.org/uniprot/H8GVP7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/745776:DGO_RS08690 ^@ http://purl.uniprot.org/uniprot/H8GW91 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS15095 ^@ http://purl.uniprot.org/uniprot/H8H0M6 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/745776:DGO_RS00305 ^@ http://purl.uniprot.org/uniprot/H8GSN2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.|||Homodimer. http://togogenome.org/gene/745776:DGO_RS10550 ^@ http://purl.uniprot.org/uniprot/H8GY93 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/745776:DGO_RS05790 ^@ http://purl.uniprot.org/uniprot/H8GZU9 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/745776:DGO_RS16565 ^@ http://purl.uniprot.org/uniprot/H8H0E8 ^@ Similarity ^@ Belongs to the catalase family. http://togogenome.org/gene/745776:DGO_RS03210 ^@ http://purl.uniprot.org/uniprot/H8GX26 ^@ Similarity ^@ Belongs to the dihydropyrimidine dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS18220 ^@ http://purl.uniprot.org/uniprot/H8H232 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS11730 ^@ http://purl.uniprot.org/uniprot/H8GZL7 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/745776:DGO_RS00420 ^@ http://purl.uniprot.org/uniprot/H8GSQ3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/745776:DGO_RS14395 ^@ http://purl.uniprot.org/uniprot/H8GV83 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/745776:DGO_RS15825 ^@ http://purl.uniprot.org/uniprot/H8H126 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS08225 ^@ http://purl.uniprot.org/uniprot/H8GV32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS12615 ^@ http://purl.uniprot.org/uniprot/H8GSG5 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/745776:DGO_RS04385 ^@ http://purl.uniprot.org/uniprot/H8GYD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/745776:DGO_RS07935 ^@ http://purl.uniprot.org/uniprot/H8GUX5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/745776:DGO_RS04220 ^@ http://purl.uniprot.org/uniprot/H8GY27 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/745776:DGO_RS09420 ^@ http://purl.uniprot.org/uniprot/H8GWY3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/745776:DGO_RS09370 ^@ http://purl.uniprot.org/uniprot/H8GWX3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS06145 ^@ http://purl.uniprot.org/uniprot/H8GRT6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/745776:DGO_RS15865 ^@ http://purl.uniprot.org/uniprot/H8H134 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/745776:DGO_RS08620 ^@ http://purl.uniprot.org/uniprot/H8GVR5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/745776:DGO_RS24690 ^@ http://purl.uniprot.org/uniprot/H8H1Q6 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Periplasm http://togogenome.org/gene/745776:DGO_RS02605 ^@ http://purl.uniprot.org/uniprot/H8GW81 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/745776:DGO_RS20080 ^@ http://purl.uniprot.org/uniprot/H8H3E9 ^@ Similarity ^@ Belongs to the barstar family. http://togogenome.org/gene/745776:DGO_RS11970 ^@ http://purl.uniprot.org/uniprot/H8GZZ0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/745776:DGO_RS16065 ^@ http://purl.uniprot.org/uniprot/H8H040 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS21425 ^@ http://purl.uniprot.org/uniprot/H8H2Q1 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/745776:DGO_RS10575 ^@ http://purl.uniprot.org/uniprot/H8GY98 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/745776:DGO_RS00710 ^@ http://purl.uniprot.org/uniprot/H8GTB4 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/745776:DGO_RS05135 ^@ http://purl.uniprot.org/uniprot/H8GZ92 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/745776:DGO_RS08465 ^@ http://purl.uniprot.org/uniprot/H8GVN4 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/745776:DGO_RS16555 ^@ http://purl.uniprot.org/uniprot/H8H0E6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell inner membrane|||Cell membrane|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/745776:DGO_RS11195 ^@ http://purl.uniprot.org/uniprot/H8GZ31 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/745776:DGO_RS09320 ^@ http://purl.uniprot.org/uniprot/H8GWW3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/745776:DGO_RS12970 ^@ http://purl.uniprot.org/uniprot/H8GT39 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/745776:DGO_RS01705 ^@ http://purl.uniprot.org/uniprot/H8GUT1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/745776:DGO_RS17760 ^@ http://purl.uniprot.org/uniprot/H8H1R9 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/745776:DGO_RS19120 ^@ http://purl.uniprot.org/uniprot/H8H2Q3 ^@ Similarity ^@ Belongs to the HsdR family. http://togogenome.org/gene/745776:DGO_RS11725 ^@ http://purl.uniprot.org/uniprot/H8GZL6 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/745776:DGO_RS13095 ^@ http://purl.uniprot.org/uniprot/H8GT64 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/745776:DGO_RS14475 ^@ http://purl.uniprot.org/uniprot/H8GVA0 ^@ Function|||Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.|||Catalyzes the biosynthesis of agmatine from arginine. http://togogenome.org/gene/745776:DGO_RS13900 ^@ http://purl.uniprot.org/uniprot/H8GUI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS12065 ^@ http://purl.uniprot.org/uniprot/H8H008 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS06385 ^@ http://purl.uniprot.org/uniprot/H8GSA8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/745776:DGO_RS05780 ^@ http://purl.uniprot.org/uniprot/H8GZU7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/745776:DGO_RS16320 ^@ http://purl.uniprot.org/uniprot/H8H099 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/745776:DGO_RS17305 ^@ http://purl.uniprot.org/uniprot/H8H1G2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS12885 ^@ http://purl.uniprot.org/uniprot/H8GSL6 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS00885 ^@ http://purl.uniprot.org/uniprot/H8GTE9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/745776:DGO_RS05590 ^@ http://purl.uniprot.org/uniprot/H8GZR1 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnD subfamily.|||Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/745776:DGO_RS07665 ^@ http://purl.uniprot.org/uniprot/H8GUB1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/745776:DGO_RS02590 ^@ http://purl.uniprot.org/uniprot/H8GW78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/745776:DGO_RS13405 ^@ http://purl.uniprot.org/uniprot/H8GTT4 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/745776:DGO_RS09325 ^@ http://purl.uniprot.org/uniprot/H8GWW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/745776:DGO_RS06725 ^@ http://purl.uniprot.org/uniprot/H8GSW1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/745776:DGO_RS05275 ^@ http://purl.uniprot.org/uniprot/H8GZB8 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/745776:DGO_RS03810 ^@ http://purl.uniprot.org/uniprot/H8GXM2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreF family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/745776:DGO_RS16035 ^@ http://purl.uniprot.org/uniprot/H8H167 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS12825 ^@ http://purl.uniprot.org/uniprot/H8GSK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS09745 ^@ http://purl.uniprot.org/uniprot/H8GXC6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/745776:DGO_RS05770 ^@ http://purl.uniprot.org/uniprot/H8GZU5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/745776:DGO_RS11100 ^@ http://purl.uniprot.org/uniprot/H8GZ13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS09305 ^@ http://purl.uniprot.org/uniprot/H8GWW0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/745776:DGO_RS16470 ^@ http://purl.uniprot.org/uniprot/H8H0C9 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/745776:DGO_RS05925 ^@ http://purl.uniprot.org/uniprot/H8GRP3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS15930 ^@ http://purl.uniprot.org/uniprot/H8H146 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/745776:DGO_RS11305 ^@ http://purl.uniprot.org/uniprot/H8GZ52 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/745776:DGO_RS06400 ^@ http://purl.uniprot.org/uniprot/H8GSB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/745776:DGO_RS04910 ^@ http://purl.uniprot.org/uniprot/H8GYW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS07925 ^@ http://purl.uniprot.org/uniprot/H8GUX1 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS21415 ^@ http://purl.uniprot.org/uniprot/H8H2P2 ^@ Function ^@ TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. http://togogenome.org/gene/745776:DGO_RS01465 ^@ http://purl.uniprot.org/uniprot/H8GUN3 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. http://togogenome.org/gene/745776:DGO_RS11115 ^@ http://purl.uniprot.org/uniprot/H8GZ16 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HSP33 family.|||Cytoplasm|||Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.|||Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive. http://togogenome.org/gene/745776:DGO_RS10335 ^@ http://purl.uniprot.org/uniprot/H8GY51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS13015 ^@ http://purl.uniprot.org/uniprot/H8GT48 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/745776:DGO_RS07305 ^@ http://purl.uniprot.org/uniprot/H8GTN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS08750 ^@ http://purl.uniprot.org/uniprot/H8GWA3 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/745776:DGO_RS13060 ^@ http://purl.uniprot.org/uniprot/H8GT57 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/745776:DGO_RS08100 ^@ http://purl.uniprot.org/uniprot/H8GV07 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/745776:DGO_RS05980 ^@ http://purl.uniprot.org/uniprot/H8GRQ4 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/745776:DGO_RS20115 ^@ http://purl.uniprot.org/uniprot/H8H3G1 ^@ Caution|||Similarity ^@ Belongs to the globin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/745776:DGO_RS01190 ^@ http://purl.uniprot.org/uniprot/H8GU16 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/745776:DGO_RS09300 ^@ http://purl.uniprot.org/uniprot/H8GWV9 ^@ Similarity ^@ Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily. http://togogenome.org/gene/745776:DGO_RS16090 ^@ http://purl.uniprot.org/uniprot/H8H045 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/745776:DGO_RS02640 ^@ http://purl.uniprot.org/uniprot/H8GW88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS13975 ^@ http://purl.uniprot.org/uniprot/H8GUJ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS08410 ^@ http://purl.uniprot.org/uniprot/H8GVM4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS13460 ^@ http://purl.uniprot.org/uniprot/H8GTU5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS03965 ^@ http://purl.uniprot.org/uniprot/H8GXY0 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/745776:DGO_RS19985 ^@ http://purl.uniprot.org/uniprot/H8H3C0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArsB family.|||Cell membrane|||Involved in arsenical resistance. Thought to form the channel of an arsenite pump.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/745776:DGO_RS05755 ^@ http://purl.uniprot.org/uniprot/H8GZU3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/745776:DGO_RS16240 ^@ http://purl.uniprot.org/uniprot/H8H074 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/745776:DGO_RS10755 ^@ http://purl.uniprot.org/uniprot/H8GYL5 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/745776:DGO_RS11495 ^@ http://purl.uniprot.org/uniprot/H8GZG9 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/745776:DGO_RS04070 ^@ http://purl.uniprot.org/uniprot/H8GY01 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/745776:DGO_RS11670 ^@ http://purl.uniprot.org/uniprot/H8GZK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/745776:DGO_RS06470 ^@ http://purl.uniprot.org/uniprot/H8GSC3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS05990 ^@ http://purl.uniprot.org/uniprot/H8GRQ6 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/745776:DGO_RS13625 ^@ http://purl.uniprot.org/uniprot/H8GTX6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/745776:DGO_RS11990 ^@ http://purl.uniprot.org/uniprot/H8GZZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS08890 ^@ http://purl.uniprot.org/uniprot/H8GWD1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS00790 ^@ http://purl.uniprot.org/uniprot/H8GTD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS14780 ^@ http://purl.uniprot.org/uniprot/H8GVW9 ^@ Similarity ^@ Belongs to the XseB family. http://togogenome.org/gene/745776:DGO_RS16880 ^@ http://purl.uniprot.org/uniprot/H8H0L4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/745776:DGO_RS15615 ^@ http://purl.uniprot.org/uniprot/H8H0X9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS13890 ^@ http://purl.uniprot.org/uniprot/H8GUI1 ^@ Similarity ^@ Belongs to the UbiD family. http://togogenome.org/gene/745776:DGO_RS14575 ^@ http://purl.uniprot.org/uniprot/H8GVT0 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family. http://togogenome.org/gene/745776:DGO_RS07225 ^@ http://purl.uniprot.org/uniprot/H8GTL7 ^@ Similarity ^@ Belongs to the BshC family. http://togogenome.org/gene/745776:DGO_RS05975 ^@ http://purl.uniprot.org/uniprot/H8GRQ3 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/745776:DGO_RS16645 ^@ http://purl.uniprot.org/uniprot/H8H0G6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. http://togogenome.org/gene/745776:DGO_RS14660 ^@ http://purl.uniprot.org/uniprot/H8GVU5 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Periplasm http://togogenome.org/gene/745776:DGO_RS16170 ^@ http://purl.uniprot.org/uniprot/H8H059 ^@ Similarity ^@ Belongs to the malate synthase family. http://togogenome.org/gene/745776:DGO_RS08740 ^@ http://purl.uniprot.org/uniprot/H8GWA1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/745776:DGO_RS11685 ^@ http://purl.uniprot.org/uniprot/H8GZK8 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/745776:DGO_RS14140 ^@ http://purl.uniprot.org/uniprot/H8GUM7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS16400 ^@ http://purl.uniprot.org/uniprot/H8H0B5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/745776:DGO_RS17740 ^@ http://purl.uniprot.org/uniprot/H8H1R5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/745776:DGO_RS07700 ^@ http://purl.uniprot.org/uniprot/H8GUB8 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/745776:DGO_RS13110 ^@ http://purl.uniprot.org/uniprot/H8GT67 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/745776:DGO_RS11720 ^@ http://purl.uniprot.org/uniprot/H8GZL5 ^@ Subcellular Location Annotation ^@ Membrane|||Nucleus membrane http://togogenome.org/gene/745776:DGO_RS08610 ^@ http://purl.uniprot.org/uniprot/H8GVR3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/745776:DGO_RS00430 ^@ http://purl.uniprot.org/uniprot/H8GSQ5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/745776:DGO_RS11445 ^@ http://purl.uniprot.org/uniprot/H8GZG0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RNase HII family.|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/745776:DGO_RS13040 ^@ http://purl.uniprot.org/uniprot/H8GT53 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/745776:DGO_RS11595 ^@ http://purl.uniprot.org/uniprot/H8GZI9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/745776:DGO_RS05235 ^@ http://purl.uniprot.org/uniprot/H8GZB1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer.|||In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.|||In the N-terminal section; belongs to the MIP18 family. http://togogenome.org/gene/745776:DGO_RS15490 ^@ http://purl.uniprot.org/uniprot/H8H0V5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/745776:DGO_RS15880 ^@ http://purl.uniprot.org/uniprot/H8H137 ^@ Similarity ^@ Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family. http://togogenome.org/gene/745776:DGO_RS10545 ^@ http://purl.uniprot.org/uniprot/H8GY92 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/745776:DGO_RS00615 ^@ http://purl.uniprot.org/uniprot/H8GST9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/745776:DGO_RS16885 ^@ http://purl.uniprot.org/uniprot/H8H0L5 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/745776:DGO_RS12030 ^@ http://purl.uniprot.org/uniprot/H8H002 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/745776:DGO_RS01690 ^@ http://purl.uniprot.org/uniprot/H8GUS8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS18310 ^@ http://purl.uniprot.org/uniprot/H8H250 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/745776:DGO_RS14600 ^@ http://purl.uniprot.org/uniprot/H8GVT5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS17580 ^@ http://purl.uniprot.org/uniprot/H8H1N2 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Periplasm http://togogenome.org/gene/745776:DGO_RS00020 ^@ http://purl.uniprot.org/uniprot/H8GS36 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/745776:DGO_RS09415 ^@ http://purl.uniprot.org/uniprot/H8GWY2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/745776:DGO_RS05850 ^@ http://purl.uniprot.org/uniprot/H8GZV6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/745776:DGO_RS04740 ^@ http://purl.uniprot.org/uniprot/H8GYT6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphopentomutase family.|||Binds 1 or 2 manganese ions.|||Cytoplasm|||Phosphotransfer between the C1 and C5 carbon atoms of pentose. http://togogenome.org/gene/745776:DGO_RS16440 ^@ http://purl.uniprot.org/uniprot/H8H0C4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/745776:DGO_RS19080 ^@ http://purl.uniprot.org/uniprot/H8H2P3 ^@ Similarity ^@ In the N-terminal section; belongs to the cytochrome P450 family. http://togogenome.org/gene/745776:DGO_RS07445 ^@ http://purl.uniprot.org/uniprot/H8GTR3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/745776:DGO_RS12760 ^@ http://purl.uniprot.org/uniprot/H8GSJ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/745776:DGO_RS08045 ^@ http://purl.uniprot.org/uniprot/H8GUZ6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/745776:DGO_RS00460 ^@ http://purl.uniprot.org/uniprot/H8GSR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/745776:DGO_RS02145 ^@ http://purl.uniprot.org/uniprot/H8GVH3 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/745776:DGO_RS19740 ^@ http://purl.uniprot.org/uniprot/H8H356 ^@ Similarity ^@ Belongs to the ParB family.