http://togogenome.org/gene/69656:D1869_RS00900 ^@ http://purl.uniprot.org/uniprot/A0A650CDQ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NDK family.|||Cytoplasm|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/69656:D1869_RS01205 ^@ http://purl.uniprot.org/uniprot/A0A650CDP4 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.|||The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/69656:D1869_RS01885 ^@ http://purl.uniprot.org/uniprot/A0A650CE75 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/69656:D1869_RS11645 ^@ http://purl.uniprot.org/uniprot/A0A650CJB5 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the ferredoxin--NADP reductase type 2 family.|||Binds 1 FAD per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/69656:D1869_RS11305 ^@ http://purl.uniprot.org/uniprot/A0A650CIU9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/69656:D1869_RS10630 ^@ http://purl.uniprot.org/uniprot/A0A650CIJ4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/69656:D1869_RS02035 ^@ http://purl.uniprot.org/uniprot/A0A650CEX9 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. http://togogenome.org/gene/69656:D1869_RS08150 ^@ http://purl.uniprot.org/uniprot/A0A650CKY3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/69656:D1869_RS12425 ^@ http://purl.uniprot.org/uniprot/A0A650CK97 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/69656:D1869_RS01160 ^@ http://purl.uniprot.org/uniprot/A0A650CDN1 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the FBP aldolase/phosphatase family.|||Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).|||Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.|||Homooctamer; dimer of tetramers. http://togogenome.org/gene/69656:D1869_RS00390 ^@ http://purl.uniprot.org/uniprot/A0A650CD97 ^@ Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS8 family.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/69656:D1869_RS00885 ^@ http://purl.uniprot.org/uniprot/A0A650CE11 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/69656:D1869_RS06995 ^@ http://purl.uniprot.org/uniprot/A0A650CGL3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/69656:D1869_RS01505 ^@ http://purl.uniprot.org/uniprot/A0A650CE13 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS24 family. http://togogenome.org/gene/69656:D1869_RS12145 ^@ http://purl.uniprot.org/uniprot/A0A650CJA0 ^@ Similarity ^@ Belongs to the complex I subunit 3 family. http://togogenome.org/gene/69656:D1869_RS07985 ^@ http://purl.uniprot.org/uniprot/A0A650CHH5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Cytoplasm|||Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.|||Part of the 50S ribosomal subunit. Probably part of the RNase P complex. http://togogenome.org/gene/69656:D1869_RS02135 ^@ http://purl.uniprot.org/uniprot/A0A650CKY9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/69656:D1869_RS01905 ^@ http://purl.uniprot.org/uniprot/A0A650CDZ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e. http://togogenome.org/gene/69656:D1869_RS07780 ^@ http://purl.uniprot.org/uniprot/A0A650CH57 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/69656:D1869_RS07685 ^@ http://purl.uniprot.org/uniprot/A0A650CH53 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.|||Membrane http://togogenome.org/gene/69656:D1869_RS11655 ^@ http://purl.uniprot.org/uniprot/A0A650CJX1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/69656:D1869_RS12525 ^@ http://purl.uniprot.org/uniprot/A0A650CJE2 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/69656:D1869_RS07715 ^@ http://purl.uniprot.org/uniprot/A0A650CGV1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL39 family. http://togogenome.org/gene/69656:D1869_RS07135 ^@ http://purl.uniprot.org/uniprot/A0A650CGS9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/69656:D1869_RS07505 ^@ http://purl.uniprot.org/uniprot/A0A650CH05 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP. http://togogenome.org/gene/69656:D1869_RS08220 ^@ http://purl.uniprot.org/uniprot/A0A650CHF0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/69656:D1869_RS03380 ^@ http://purl.uniprot.org/uniprot/A0A7J9RWJ8 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/69656:D1869_RS01185 ^@ http://purl.uniprot.org/uniprot/A0A650CDZ4 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/69656:D1869_RS01830 ^@ http://purl.uniprot.org/uniprot/A0A650CE79 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/69656:D1869_RS02085 ^@ http://purl.uniprot.org/uniprot/A0A650CEM7 ^@ Similarity ^@ Belongs to the UPF0147 family. http://togogenome.org/gene/69656:D1869_RS00910 ^@ http://purl.uniprot.org/uniprot/A0A650CDJ5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS28 family. http://togogenome.org/gene/69656:D1869_RS01325 ^@ http://purl.uniprot.org/uniprot/A0A650CDY1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL37 family.|||Binds 1 zinc ion per subunit.|||Binds to the 23S rRNA.|||Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. http://togogenome.org/gene/69656:D1869_RS02055 ^@ http://purl.uniprot.org/uniprot/A0A650CE46 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic RPB4 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.|||Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure. http://togogenome.org/gene/69656:D1869_RS03705 ^@ http://purl.uniprot.org/uniprot/A0A650CEZ5 ^@ Similarity ^@ Belongs to the snRNP Sm proteins family. http://togogenome.org/gene/69656:D1869_RS07925 ^@ http://purl.uniprot.org/uniprot/A0A650CGY7 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/69656:D1869_RS00860 ^@ http://purl.uniprot.org/uniprot/A0A650CDI0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NusA family.|||Cytoplasm|||Participates in transcription termination. http://togogenome.org/gene/69656:D1869_RS07710 ^@ http://purl.uniprot.org/uniprot/A0A650CH27 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL31 family.|||Belongs to the ribosomal protein L31e family. http://togogenome.org/gene/69656:D1869_RS00905 ^@ http://purl.uniprot.org/uniprot/A0A650CDQ6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL24 family.|||Binds 1 zinc ion per subunit.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14. http://togogenome.org/gene/69656:D1869_RS12435 ^@ http://purl.uniprot.org/uniprot/A0A650CJE9 ^@ Function|||Subunit ^@ Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2-oxobutyrate to form their CoA derivatives.|||Heterodimer composed of an alpha and a beta subunit. http://togogenome.org/gene/69656:D1869_RS00835 ^@ http://purl.uniprot.org/uniprot/A0A650CE00 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/69656:D1869_RS08395 ^@ http://purl.uniprot.org/uniprot/A0A650CL63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/69656:D1869_RS07705 ^@ http://purl.uniprot.org/uniprot/A0A650CH00 ^@ Function|||Similarity ^@ Belongs to the eIF-6 family.|||Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. http://togogenome.org/gene/69656:D1869_RS01995 ^@ http://purl.uniprot.org/uniprot/A0A650CE36 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.|||The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/69656:D1869_RS01610 ^@ http://purl.uniprot.org/uniprot/A0A650CE34 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.|||Heterotrimer composed of an alpha, a beta and a gamma chain.|||eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. http://togogenome.org/gene/69656:D1869_RS02705 ^@ http://purl.uniprot.org/uniprot/A0A650CEG5 ^@ Similarity ^@ Belongs to the RuvB family. http://togogenome.org/gene/69656:D1869_RS02375 ^@ http://purl.uniprot.org/uniprot/A0A650CEI1 ^@ Function|||Similarity ^@ Belongs to the eIF-1A family.|||Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. http://togogenome.org/gene/69656:D1869_RS13685 ^@ http://purl.uniprot.org/uniprot/A0A650CJW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/69656:D1869_RS06970 ^@ http://purl.uniprot.org/uniprot/A0A650CHD6 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/69656:D1869_RS04035 ^@ http://purl.uniprot.org/uniprot/A0A650CFZ9 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/69656:D1869_RS08210 ^@ http://purl.uniprot.org/uniprot/A0A650CHD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/69656:D1869_RS10685 ^@ http://purl.uniprot.org/uniprot/A0A650CIK2 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/69656:D1869_RS01440 ^@ http://purl.uniprot.org/uniprot/A0A650CE30 ^@ Caution|||Function|||Similarity ^@ Belongs to the TFIIB family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). http://togogenome.org/gene/69656:D1869_RS01815 ^@ http://purl.uniprot.org/uniprot/A0A650CEH3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL19 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/69656:D1869_RS00570 ^@ http://purl.uniprot.org/uniprot/A0A650CDC5 ^@ Cofactor|||Function|||Miscellaneous|||Similarity ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/69656:D1869_RS01445 ^@ http://purl.uniprot.org/uniprot/A0A650CEM1 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/69656:D1869_RS01450 ^@ http://purl.uniprot.org/uniprot/A0A650CE02 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.|||Binds 1 zinc ion.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/69656:D1869_RS00275 ^@ http://purl.uniprot.org/uniprot/A0A650CDE6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm http://togogenome.org/gene/69656:D1869_RS07515 ^@ http://purl.uniprot.org/uniprot/A0A650CGN7 ^@ Function|||Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.|||Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway. http://togogenome.org/gene/69656:D1869_RS01850 ^@ http://purl.uniprot.org/uniprot/A0A650CE68 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||Located at the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/69656:D1869_RS01895 ^@ http://purl.uniprot.org/uniprot/A0A650CE15 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29. http://togogenome.org/gene/69656:D1869_RS00305 ^@ http://purl.uniprot.org/uniprot/A0A650CDF2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/69656:D1869_RS11320 ^@ http://purl.uniprot.org/uniprot/A0A650CIV3 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/69656:D1869_RS03050 ^@ http://purl.uniprot.org/uniprot/A0A650CEV7 ^@ Similarity ^@ Belongs to the 7 kDa DNA-binding/endoribonuclease P2 family. http://togogenome.org/gene/69656:D1869_RS08490 ^@ http://purl.uniprot.org/uniprot/A0A650CI53 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Membrane http://togogenome.org/gene/69656:D1869_RS07480 ^@ http://purl.uniprot.org/uniprot/A0A650CH83 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eIF-5A family.|||Cytoplasm|||Functions by promoting the formation of the first peptide bond. http://togogenome.org/gene/69656:D1869_RS00530 ^@ http://purl.uniprot.org/uniprot/A0A650CDV4 ^@ Function|||Similarity ^@ Belongs to the EF-1-beta/EF-1-delta family.|||Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. http://togogenome.org/gene/69656:D1869_RS01875 ^@ http://purl.uniprot.org/uniprot/A0A650CEU7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/69656:D1869_RS11300 ^@ http://purl.uniprot.org/uniprot/A0A650CJ60 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/69656:D1869_RS01165 ^@ http://purl.uniprot.org/uniprot/A0A650CDT5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS17 family. http://togogenome.org/gene/69656:D1869_RS11270 ^@ http://purl.uniprot.org/uniprot/A0A650CIU2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/69656:D1869_RS07060 ^@ http://purl.uniprot.org/uniprot/A0A650CGI4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/69656:D1869_RS07050 ^@ http://purl.uniprot.org/uniprot/A0A650CGM4 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/69656:D1869_RS00605 ^@ http://purl.uniprot.org/uniprot/A0A650CDE1 ^@ Function|||Similarity ^@ Belongs to the ATP-dependent DNA ligase family.|||DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. http://togogenome.org/gene/69656:D1869_RS00655 ^@ http://purl.uniprot.org/uniprot/A0A650CDL7 ^@ Function|||Similarity ^@ Belongs to the AdoMet synthase 2 family.|||Catalyzes the formation of S-adenosylmethionine from methionine and ATP. http://togogenome.org/gene/69656:D1869_RS08085 ^@ http://purl.uniprot.org/uniprot/A0A650CH97 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/69656:D1869_RS11275 ^@ http://purl.uniprot.org/uniprot/A0A650CIQ6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.|||Binds 1 zinc ion.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/69656:D1869_RS08195 ^@ http://purl.uniprot.org/uniprot/A0A650CHB5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/69656:D1869_RS07605 ^@ http://purl.uniprot.org/uniprot/A0A650CH25 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/69656:D1869_RS07400 ^@ http://purl.uniprot.org/uniprot/A0A650CGY2 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/69656:D1869_RS02825 ^@ http://purl.uniprot.org/uniprot/A0A650CEQ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Forms a complex with TatA.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. http://togogenome.org/gene/69656:D1869_RS02745 ^@ http://purl.uniprot.org/uniprot/A0A650CEQ8 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. Prx6 subfamily.|||Cytoplasm|||Homodecamer. Pentamer of dimers that assemble into a ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/69656:D1869_RS02765 ^@ http://purl.uniprot.org/uniprot/A0A650CEP1 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/69656:D1869_RS00695 ^@ http://purl.uniprot.org/uniprot/A0A650CDT1 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/69656:D1869_RS11710 ^@ http://purl.uniprot.org/uniprot/A0A650CL08 ^@ Similarity ^@ Belongs to the AP endonuclease 2 family. http://togogenome.org/gene/69656:D1869_RS08335 ^@ http://purl.uniprot.org/uniprot/A0A7J9RQ95 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/69656:D1869_RS01890 ^@ http://purl.uniprot.org/uniprot/A0A650CE14 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/69656:D1869_RS01920 ^@ http://purl.uniprot.org/uniprot/A0A650CEA9 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/69656:D1869_RS01565 ^@ http://purl.uniprot.org/uniprot/A0A650CDV5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS25 family. http://togogenome.org/gene/69656:D1869_RS07435 ^@ http://purl.uniprot.org/uniprot/A0A650CGZ7 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.|||Belongs to the histone-like Alba family.|||Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.|||Chromosome|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/69656:D1869_RS01700 ^@ http://purl.uniprot.org/uniprot/A0A650CE71 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL14 family. http://togogenome.org/gene/69656:D1869_RS11290 ^@ http://purl.uniprot.org/uniprot/A0A650CIU8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL18 family. http://togogenome.org/gene/69656:D1869_RS08300 ^@ http://purl.uniprot.org/uniprot/A0A650CHD3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/69656:D1869_RS01075 ^@ http://purl.uniprot.org/uniprot/A0A650CDT8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SEC61-beta family.|||Cell membrane|||Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.|||Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.|||Membrane http://togogenome.org/gene/69656:D1869_RS07445 ^@ http://purl.uniprot.org/uniprot/A0A650CH13 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.|||Belongs to the histone-like Alba family.|||Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.|||Chromosome|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/69656:D1869_RS06550 ^@ http://purl.uniprot.org/uniprot/A0A650CG64 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/69656:D1869_RS01855 ^@ http://purl.uniprot.org/uniprot/A0A650CDY4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges. http://togogenome.org/gene/69656:D1869_RS07500 ^@ http://purl.uniprot.org/uniprot/A0A650CKP9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils.|||Belongs to the Cren7 family.|||Cytoplasm|||Methylated at multiple sites, to varying extents.|||Monomer. http://togogenome.org/gene/69656:D1869_RS07880 ^@ http://purl.uniprot.org/uniprot/A0A7J9RNP4 ^@ Caution ^@ The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. http://togogenome.org/gene/69656:D1869_RS12175 ^@ http://purl.uniprot.org/uniprot/A0A650CJ94 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/69656:D1869_RS11545 ^@ http://purl.uniprot.org/uniprot/A0A650CJV0 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/69656:D1869_RS01990 ^@ http://purl.uniprot.org/uniprot/A0A650CE95 ^@ Similarity ^@ Belongs to the SDO1/SBDS family. http://togogenome.org/gene/69656:D1869_RS02025 ^@ http://purl.uniprot.org/uniprot/A0A650CEL7 ^@ Similarity ^@ In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family. http://togogenome.org/gene/69656:D1869_RS11440 ^@ http://purl.uniprot.org/uniprot/A0A650CEV7 ^@ Similarity ^@ Belongs to the 7 kDa DNA-binding/endoribonuclease P2 family. http://togogenome.org/gene/69656:D1869_RS01970 ^@ http://purl.uniprot.org/uniprot/A0A650CEK6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.|||Binds to the 23S rRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/69656:D1869_RS01985 ^@ http://purl.uniprot.org/uniprot/A0A650CEB0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RRP4 family.|||Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.|||Cytoplasm|||Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. http://togogenome.org/gene/69656:D1869_RS10625 ^@ http://purl.uniprot.org/uniprot/A0A650CIN9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/69656:D1869_RS01835 ^@ http://purl.uniprot.org/uniprot/A0A650CE62 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles.|||Part of the 30S ribosomal subunit.