http://togogenome.org/gene/67260:CP977_RS14200 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILC8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/67260:CP977_RS23760 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT78 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/67260:CP977_RS16145 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITB4 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/67260:CP977_RS16520 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMQ4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS20625 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVD0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/67260:CP977_RS09900 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUI4 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/67260:CP977_RS08080 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL83 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/67260:CP977_RS22420 ^@ http://purl.uniprot.org/uniprot/A0A5J6J0F9 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/67260:CP977_RS09940 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMS5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons. http://togogenome.org/gene/67260:CP977_RS28075 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVJ2 ^@ Similarity ^@ Belongs to the glycosyltransferase 28 family. http://togogenome.org/gene/67260:CP977_RS08180 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPF5 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/67260:CP977_RS14320 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILS3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S41B family.|||Cytoplasm|||Degrades oligopeptides. http://togogenome.org/gene/67260:CP977_RS32600 ^@ http://purl.uniprot.org/uniprot/A0A5J6J1P0 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/67260:CP977_RS19615 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUW9 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/67260:CP977_RS06570 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/67260:CP977_RS20700 ^@ http://purl.uniprot.org/uniprot/A0A5J6J0R0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/67260:CP977_RS05185 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL61 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS24285 ^@ http://purl.uniprot.org/uniprot/A0A5J6J010 ^@ Similarity ^@ Belongs to the bacterial phospholipase C family. http://togogenome.org/gene/67260:CP977_RS06645 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL54 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS04220 ^@ http://purl.uniprot.org/uniprot/A0A5J6IGE1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/67260:CP977_RS24125 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVX6 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/67260:CP977_RS16865 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQ08 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS06990 ^@ http://purl.uniprot.org/uniprot/A0A5J6IK81 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/67260:CP977_RS31020 ^@ http://purl.uniprot.org/uniprot/A0A5J6J5C7 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS06125 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISP0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase-binding protein RbpA family.|||Bind 1 Zn(2+) per subunit.|||Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.|||Forms a complex with the RNAP catalytic core and with free principal sigma factors. http://togogenome.org/gene/67260:CP977_RS05035 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJ46 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS20680 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVE0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/67260:CP977_RS03410 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRS6 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the peroxidase family. Peroxidase/catalase subfamily.|||Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.|||Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS08245 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWQ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS16605 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPQ8 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/67260:CP977_RS20655 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQ53 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/67260:CP977_RS06560 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKJ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/67260:CP977_RS04410 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS17905 ^@ http://purl.uniprot.org/uniprot/A0A5J6IN25 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/67260:CP977_RS15545 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRE9 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/67260:CP977_RS27665 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZ10 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS24140 ^@ http://purl.uniprot.org/uniprot/A0A5J6IX36 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/67260:CP977_RS16435 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPN1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/67260:CP977_RS09680 ^@ http://purl.uniprot.org/uniprot/A0A5J6IV77 ^@ Caution|||PTM|||Subcellular Location Annotation|||Subunit ^@ Binds 2 heme c groups covalently per subunit.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit. http://togogenome.org/gene/67260:CP977_RS11820 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWD7 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/67260:CP977_RS19555 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRB3 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnD subfamily.|||Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/67260:CP977_RS05735 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHJ4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/67260:CP977_RS24240 ^@ http://purl.uniprot.org/uniprot/A0A5J6IX56 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/67260:CP977_RS11465 ^@ http://purl.uniprot.org/uniprot/A0A5J6IW58 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/67260:CP977_RS23300 ^@ http://purl.uniprot.org/uniprot/A0A5J6IU24 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M7 family.|||Binds 1 Ca(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Secreted http://togogenome.org/gene/67260:CP977_RS22720 ^@ http://purl.uniprot.org/uniprot/A0A5J6J1N3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS08260 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITS6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF1 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS31740 ^@ http://purl.uniprot.org/uniprot/A0A5J6IY22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS15810 ^@ http://purl.uniprot.org/uniprot/A0A5J6IY83 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS12210 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMN7 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/67260:CP977_RS09135 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUX2 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/67260:CP977_RS25025 ^@ http://purl.uniprot.org/uniprot/A0A5J6J1Q1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS12465 ^@ http://purl.uniprot.org/uniprot/A0A5J6IN55 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/67260:CP977_RS22430 ^@ http://purl.uniprot.org/uniprot/A0A5J6J1I5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/67260:CP977_RS18150 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUA0 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/67260:CP977_RS15510 ^@ http://purl.uniprot.org/uniprot/A0A5J6IX23 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DisA family.|||Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.|||Homooctamer.|||Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. http://togogenome.org/gene/67260:CP977_RS20290 ^@ http://purl.uniprot.org/uniprot/A0A5J6J0J9 ^@ Similarity ^@ Belongs to the peptidase M28 family. M28A subfamily. http://togogenome.org/gene/67260:CP977_RS20725 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRR7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/67260:CP977_RS07150 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILD4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/67260:CP977_RS06920 ^@ http://purl.uniprot.org/uniprot/A0A5J6INF7 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/67260:CP977_RS22655 ^@ http://purl.uniprot.org/uniprot/A0A5J6J1M5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatB family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/67260:CP977_RS12130 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKS1 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/67260:CP977_RS03780 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJT3 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS20895 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRV2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cell surface|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.|||capsule|||cell wall http://togogenome.org/gene/67260:CP977_RS03275 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRQ2 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/67260:CP977_RS11290 ^@ http://purl.uniprot.org/uniprot/A0A5J6J6V6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/67260:CP977_RS27850 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS11865 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMJ3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS28015 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS18450 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS14295 ^@ http://purl.uniprot.org/uniprot/A0A5J6INY1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS21650 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUP3 ^@ Similarity ^@ Belongs to the adenylyl cyclase class-3 family. http://togogenome.org/gene/67260:CP977_RS13665 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL39 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family. http://togogenome.org/gene/67260:CP977_RS17880 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRK5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS13635 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.|||Membrane http://togogenome.org/gene/67260:CP977_RS09340 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILT1 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/67260:CP977_RS20735 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRV0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/67260:CP977_RS24495 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the beta sliding clamp family.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS26335 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVG5 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS31500 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVF6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/67260:CP977_RS24900 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUR2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/67260:CP977_RS10595 ^@ http://purl.uniprot.org/uniprot/A0A5J6IK18 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS10745 ^@ http://purl.uniprot.org/uniprot/A0A5J6IN58 ^@ Function ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/67260:CP977_RS10405 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVM3 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/67260:CP977_RS07205 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKA9 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.|||The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/67260:CP977_RS14515 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQS7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS06720 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJX2 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/67260:CP977_RS20615 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISS8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/67260:CP977_RS16615 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPW5 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/67260:CP977_RS20590 ^@ http://purl.uniprot.org/uniprot/A0A5J6J0P4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS15965 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPM6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS22290 ^@ http://purl.uniprot.org/uniprot/A0A5J6IW75 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/67260:CP977_RS14155 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXE5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS23720 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRR6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/67260:CP977_RS09325 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMI6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DivIVA family.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS22150 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISF8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/67260:CP977_RS08715 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL20 ^@ Function|||Similarity ^@ Belongs to the RapZ-like family.|||Displays ATPase and GTPase activities. http://togogenome.org/gene/67260:CP977_RS07245 ^@ http://purl.uniprot.org/uniprot/A0A5J6IM96 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS06430 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL15 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/67260:CP977_RS30230 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUK5 ^@ Similarity ^@ Belongs to the thioesterase family. http://togogenome.org/gene/67260:CP977_RS04095 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/67260:CP977_RS28210 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZB1 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. http://togogenome.org/gene/67260:CP977_RS09160 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL99 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/67260:CP977_RS20600 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZ44 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/67260:CP977_RS09350 ^@ http://purl.uniprot.org/uniprot/A0A5J6IIZ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/67260:CP977_RS29315 ^@ http://purl.uniprot.org/uniprot/A0A5J6J3X9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS25785 ^@ http://purl.uniprot.org/uniprot/A0A5J6IU07 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/67260:CP977_RS09685 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS06880 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHS1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS30600 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXI1 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/67260:CP977_RS10340 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJH7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/67260:CP977_RS12145 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMM9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS16915 ^@ http://purl.uniprot.org/uniprot/A0A5J6IX77 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/67260:CP977_RS13230 ^@ http://purl.uniprot.org/uniprot/A0A5J6IN37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Membrane http://togogenome.org/gene/67260:CP977_RS13610 ^@ http://purl.uniprot.org/uniprot/A0A5J6IW62 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/67260:CP977_RS06575 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITI8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/67260:CP977_RS06010 ^@ http://purl.uniprot.org/uniprot/A0A5J6IK99 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/67260:CP977_RS09125 ^@ http://purl.uniprot.org/uniprot/A0A5J6IU52 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/67260:CP977_RS25195 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRJ9 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS21465 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS76 ^@ Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer. http://togogenome.org/gene/67260:CP977_RS06195 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITB0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS02210 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKJ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the protease inhibitor I16 (SSI) family.|||Homodimer.|||Secreted|||Strong inhibitor of bacterial serine proteases such as subtilisin. http://togogenome.org/gene/67260:CP977_RS19100 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQT8 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/67260:CP977_RS24920 ^@ http://purl.uniprot.org/uniprot/A0A5J6J1N2 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/67260:CP977_RS12475 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVN6 ^@ Function ^@ Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core. http://togogenome.org/gene/67260:CP977_RS14335 ^@ http://purl.uniprot.org/uniprot/A0A5J6INM6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/67260:CP977_RS19095 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS43 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/67260:CP977_RS12935 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQ65 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/67260:CP977_RS02895 ^@ http://purl.uniprot.org/uniprot/A0A5J6II47 ^@ Function|||Similarity ^@ Belongs to the acetyltransferase family. EctA subfamily.|||Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A. http://togogenome.org/gene/67260:CP977_RS13590 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPF1 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS26025 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRZ2 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/67260:CP977_RS21655 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT96 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/67260:CP977_RS15120 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXW3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnE family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. http://togogenome.org/gene/67260:CP977_RS28050 ^@ http://purl.uniprot.org/uniprot/A0A5J6J415 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/67260:CP977_RS28205 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/67260:CP977_RS08695 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJ39 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS27285 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITG8 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/67260:CP977_RS31885 ^@ http://purl.uniprot.org/uniprot/A0A5J6IX38 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/67260:CP977_RS09500 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJ20 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/67260:CP977_RS33025 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVV5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/67260:CP977_RS01940 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS08690 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUI0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/67260:CP977_RS05965 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHT6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/67260:CP977_RS10855 ^@ http://purl.uniprot.org/uniprot/A0A5J6IK56 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/67260:CP977_RS10185 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJT7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS23155 ^@ http://purl.uniprot.org/uniprot/A0A5J6J1W1 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/67260:CP977_RS20575 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRR8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS08655 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL08 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/67260:CP977_RS23110 ^@ http://purl.uniprot.org/uniprot/A0A5J6IR47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/67260:CP977_RS09365 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJC9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS23260 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISZ6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/67260:CP977_RS13460 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKZ6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/67260:CP977_RS21420 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZZ4 ^@ Similarity|||Subunit ^@ Belongs to the CMP-NeuNAc synthase family.|||Belongs to the KdsC family.|||Homotetramer. http://togogenome.org/gene/67260:CP977_RS18760 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUJ0 ^@ Similarity ^@ Belongs to the CsoR family. http://togogenome.org/gene/67260:CP977_RS21925 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISF0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS13335 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL58 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/67260:CP977_RS32650 ^@ http://purl.uniprot.org/uniprot/A0A5J6J1Q0 ^@ Similarity ^@ Belongs to the FAD-binding monooxygenase family. http://togogenome.org/gene/67260:CP977_RS02910 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQX1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PhyH family. EctD subfamily.|||Homodimer.|||Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine. http://togogenome.org/gene/67260:CP977_RS09370 ^@ http://purl.uniprot.org/uniprot/A0A5J6INF8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS26235 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS26 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS09550 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILV1 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS05930 ^@ http://purl.uniprot.org/uniprot/A0A5J6IK90 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/67260:CP977_RS01855 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJM2 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/67260:CP977_RS07800 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITK3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/67260:CP977_RS08190 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/67260:CP977_RS18950 ^@ http://purl.uniprot.org/uniprot/A0A5J6IP40 ^@ Caution|||Similarity|||Subunit ^@ Belongs to the acetyltransferase Eis family.|||Homohexamer; trimer of dimers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS13265 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKX0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/67260:CP977_RS16515 ^@ http://purl.uniprot.org/uniprot/A0A5J6IYM1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/67260:CP977_RS20510 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVB2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/67260:CP977_RS21730 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVY1 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/67260:CP977_RS28445 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZF7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/67260:CP977_RS22510 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS13080 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWX4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS10040 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMU2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/67260:CP977_RS20520 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZK7 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/67260:CP977_RS15855 ^@ http://purl.uniprot.org/uniprot/A0A5J6IX82 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/67260:CP977_RS18780 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZX5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/67260:CP977_RS21595 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQR4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family.|||Homotrimer.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine. http://togogenome.org/gene/67260:CP977_RS24290 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITB6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS23040 ^@ http://purl.uniprot.org/uniprot/A0A5J6J0S1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/67260:CP977_RS13355 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPA5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/67260:CP977_RS18385 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQI0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS25140 ^@ http://purl.uniprot.org/uniprot/A0A5J6J2P6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS21455 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS49 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS21705 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQH2 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/67260:CP977_RS07400 ^@ http://purl.uniprot.org/uniprot/A0A5J6IIH8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS23685 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT26 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/67260:CP977_RS26185 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS17 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/67260:CP977_RS26245 ^@ http://purl.uniprot.org/uniprot/A0A5J6J373 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/67260:CP977_RS03665 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJR5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS12545 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWP4 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/67260:CP977_RS22890 ^@ http://purl.uniprot.org/uniprot/A0A5J6J1K8 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/67260:CP977_RS25260 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS54 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/67260:CP977_RS11440 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMB3 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/67260:CP977_RS20570 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVC1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/67260:CP977_RS27120 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Membrane http://togogenome.org/gene/67260:CP977_RS28705 ^@ http://purl.uniprot.org/uniprot/A0A5J6J3M0 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/67260:CP977_RS08165 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMU6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/67260:CP977_RS26520 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUR0 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/67260:CP977_RS15365 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQ84 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/67260:CP977_RS12340 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWG4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/67260:CP977_RS08995 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMD4 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/67260:CP977_RS10205 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILS7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS15350 ^@ http://purl.uniprot.org/uniprot/A0A5J6IM77 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/67260:CP977_RS22040 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISE1 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/67260:CP977_RS11835 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWC8 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/67260:CP977_RS28850 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVX1 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/67260:CP977_RS18415 ^@ http://purl.uniprot.org/uniprot/A0A5J6IYH0 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/67260:CP977_RS08680 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITZ1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/67260:CP977_RS19030 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT79 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/67260:CP977_RS28145 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZA1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/67260:CP977_RS13870 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPK0 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/67260:CP977_RS10325 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS23855 ^@ http://purl.uniprot.org/uniprot/A0A5J6J000 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS06185 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CbxX/CfxQ family.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS19625 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZ69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Membrane http://togogenome.org/gene/67260:CP977_RS18765 ^@ http://purl.uniprot.org/uniprot/A0A5J6IR03 ^@ Similarity ^@ Belongs to the PhoU family.|||Belongs to the UPF0111 family. http://togogenome.org/gene/67260:CP977_RS08645 ^@ http://purl.uniprot.org/uniprot/A0A5J6IN21 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS08400 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKW4 ^@ Function ^@ Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core. http://togogenome.org/gene/67260:CP977_RS29020 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWU1 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/67260:CP977_RS23230 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVH7 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/67260:CP977_RS11340 ^@ http://purl.uniprot.org/uniprot/A0A5J6IR43 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/67260:CP977_RS06395 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKH0 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/67260:CP977_RS27570 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISQ0 ^@ Similarity ^@ Belongs to the hyi family. http://togogenome.org/gene/67260:CP977_RS06390 ^@ http://purl.uniprot.org/uniprot/A0A5J6IN74 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS21050 ^@ http://purl.uniprot.org/uniprot/A0A5J6IU74 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS24915 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITY1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/67260:CP977_RS27930 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVB0 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/67260:CP977_RS20035 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRF2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/67260:CP977_RS23930 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRU4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the CobB/CobQ family.|||Involved in acetate metabolism.|||The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site. http://togogenome.org/gene/67260:CP977_RS10215 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS02745 ^@ http://purl.uniprot.org/uniprot/A0A5J6IG36 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS17690 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZF4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/67260:CP977_RS26980 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISF2 ^@ Function ^@ Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors. http://togogenome.org/gene/67260:CP977_RS31975 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/67260:CP977_RS20715 ^@ http://purl.uniprot.org/uniprot/A0A5J6IU19 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/67260:CP977_RS20955 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVJ3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/67260:CP977_RS07135 ^@ http://purl.uniprot.org/uniprot/A0A5J6IID3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/67260:CP977_RS07735 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITJ3 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/67260:CP977_RS12950 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRU9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS03615 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0060 family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS08885 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMB4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS29915 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS23625 ^@ http://purl.uniprot.org/uniprot/A0A5J6IU76 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/67260:CP977_RS15780 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT47 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/67260:CP977_RS16350 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMB9 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/67260:CP977_RS06365 ^@ http://purl.uniprot.org/uniprot/A0A5J6II09 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/67260:CP977_RS03015 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS17515 ^@ http://purl.uniprot.org/uniprot/A0A5J6IU01 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/67260:CP977_RS01770 ^@ http://purl.uniprot.org/uniprot/A0A5J6IR04 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M7 family.|||Secreted http://togogenome.org/gene/67260:CP977_RS11245 ^@ http://purl.uniprot.org/uniprot/A0A5J6IW17 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/67260:CP977_RS06205 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHS2 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Feedback inhibited by histidine. http://togogenome.org/gene/67260:CP977_RS09595 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILI3 ^@ Similarity ^@ Belongs to the arsA ATPase family. http://togogenome.org/gene/67260:CP977_RS20675 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRQ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/67260:CP977_RS13470 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL77 ^@ Cofactor|||Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/67260:CP977_RS27480 ^@ http://purl.uniprot.org/uniprot/A0A5J6IYX3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/67260:CP977_RS24995 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISB5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS06355 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHH8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/67260:CP977_RS20770 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISU5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/67260:CP977_RS11810 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRC0 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/67260:CP977_RS25015 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXJ3 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/67260:CP977_RS11285 ^@ http://purl.uniprot.org/uniprot/A0A5J6IV53 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/67260:CP977_RS25895 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/67260:CP977_RS05225 ^@ http://purl.uniprot.org/uniprot/A0A5J6J6D4 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/67260:CP977_RS14150 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILB7 ^@ Cofactor|||Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/67260:CP977_RS24645 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXB7 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/67260:CP977_RS17625 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQI6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS23530 ^@ http://purl.uniprot.org/uniprot/A0A5J6J217 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/67260:CP977_RS23790 ^@ http://purl.uniprot.org/uniprot/A0A5J6J253 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS18100 ^@ http://purl.uniprot.org/uniprot/A0A5J6IN56 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS33065 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/67260:CP977_RS32065 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVD1 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS20240 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/67260:CP977_RS29850 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITT0 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS17135 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXU7 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/67260:CP977_RS19125 ^@ http://purl.uniprot.org/uniprot/A0A5J6J023 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/67260:CP977_RS13260 ^@ http://purl.uniprot.org/uniprot/A0A5J6IW08 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/67260:CP977_RS22120 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPV3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS13645 ^@ http://purl.uniprot.org/uniprot/A0A5J6INB0 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/67260:CP977_RS31700 ^@ http://purl.uniprot.org/uniprot/A0A5J6J192 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-I family. http://togogenome.org/gene/67260:CP977_RS13210 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILA0 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/67260:CP977_RS02525 ^@ http://purl.uniprot.org/uniprot/A0A5J6IG76 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS13035 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL72 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS07445 ^@ http://purl.uniprot.org/uniprot/A0A5J6J2U8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS31725 ^@ http://purl.uniprot.org/uniprot/A0A5J6IV81 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/67260:CP977_RS20200 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISL3 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/67260:CP977_RS24205 ^@ http://purl.uniprot.org/uniprot/A0A5J6IR33 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS19915 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITN6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/67260:CP977_RS16100 ^@ http://purl.uniprot.org/uniprot/A0A5J6IYE2 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/67260:CP977_RS11730 ^@ http://purl.uniprot.org/uniprot/A0A5J6INN6 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/67260:CP977_RS27330 ^@ http://purl.uniprot.org/uniprot/A0A5J6J3P2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ETF alpha-subunit/FixB family.|||Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/67260:CP977_RS31720 ^@ http://purl.uniprot.org/uniprot/A0A5J6J5N1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS19640 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS28180 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS02555 ^@ http://purl.uniprot.org/uniprot/A0A5J6IIR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/67260:CP977_RS09935 ^@ http://purl.uniprot.org/uniprot/A0A5J6INQ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS21665 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS90 ^@ PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Cys-Ser-Gly.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS01375 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJH3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS19825 ^@ http://purl.uniprot.org/uniprot/A0A5J6INV5 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS07845 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL45 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/67260:CP977_RS19130 ^@ http://purl.uniprot.org/uniprot/A0A5J6IP58 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS21930 ^@ http://purl.uniprot.org/uniprot/A0A5J6J083 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|||Cytoplasm|||Monomer. http://togogenome.org/gene/67260:CP977_RS05165 ^@ http://purl.uniprot.org/uniprot/A0A5J6IGX1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS14125 ^@ http://purl.uniprot.org/uniprot/A0A5J6INI8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. Tam family.|||Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS20525 ^@ http://purl.uniprot.org/uniprot/A0A5J6IP62 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/67260:CP977_RS29345 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWY7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/67260:CP977_RS03375 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJL9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS17685 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMY7 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS07090 ^@ http://purl.uniprot.org/uniprot/A0A5J6IM65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS20650 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPW0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/67260:CP977_RS04090 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILJ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS19485 ^@ http://purl.uniprot.org/uniprot/A0A5J6IR05 ^@ Similarity ^@ Belongs to the CutC family. http://togogenome.org/gene/67260:CP977_RS06225 ^@ http://purl.uniprot.org/uniprot/A0A5J6IW32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane http://togogenome.org/gene/67260:CP977_RS11130 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/67260:CP977_RS24845 ^@ http://purl.uniprot.org/uniprot/A0A5J6IW98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/67260:CP977_RS21715 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUQ1 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/67260:CP977_RS20205 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRH6 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/67260:CP977_RS06320 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHU8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/67260:CP977_RS03640 ^@ http://purl.uniprot.org/uniprot/A0A5J6IG40 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/67260:CP977_RS24375 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS24690 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITH6 ^@ Function ^@ Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. http://togogenome.org/gene/67260:CP977_RS28585 ^@ http://purl.uniprot.org/uniprot/A0A5J6J3K5 ^@ Cofactor|||Similarity ^@ Belongs to the fatty acid desaturase type 2 family.|||Binds 2 iron ions per subunit. http://togogenome.org/gene/67260:CP977_RS08710 ^@ http://purl.uniprot.org/uniprot/A0A5J6IM83 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/67260:CP977_RS27080 ^@ http://purl.uniprot.org/uniprot/A0A5J6IYK9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS17695 ^@ http://purl.uniprot.org/uniprot/A0A5J6INA6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/67260:CP977_RS17805 ^@ http://purl.uniprot.org/uniprot/A0A5J6IND0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS11695 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMT8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/67260:CP977_RS20980 ^@ http://purl.uniprot.org/uniprot/A0A5J6J0V2 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS17565 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQ78 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/67260:CP977_RS32210 ^@ http://purl.uniprot.org/uniprot/A0A5J6J1H4 ^@ Function|||Subcellular Location Annotation ^@ May play a structural or regulatory role in gas vesicle synthesis.|||Vesicle|||gas vesicle http://togogenome.org/gene/67260:CP977_RS08355 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPI3 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. http://togogenome.org/gene/67260:CP977_RS24905 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITL4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ A probable RNA-binding protein.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS28095 ^@ http://purl.uniprot.org/uniprot/A0A5J6J3C5 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/67260:CP977_RS23345 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS17950 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQQ1 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/67260:CP977_RS06890 ^@ http://purl.uniprot.org/uniprot/A0A5J6II97 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS24230 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUG0 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/67260:CP977_RS14075 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWD8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS25235 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXN5 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/67260:CP977_RS14995 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXU4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS08640 ^@ http://purl.uniprot.org/uniprot/A0A5J6IIY8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 2 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/67260:CP977_RS14400 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZG5 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/67260:CP977_RS23710 ^@ http://purl.uniprot.org/uniprot/A0A5J6J246 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/67260:CP977_RS27475 ^@ http://purl.uniprot.org/uniprot/A0A5J6IV78 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS15720 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT38 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/67260:CP977_RS02865 ^@ http://purl.uniprot.org/uniprot/A0A5J6IFR9 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS09985 ^@ http://purl.uniprot.org/uniprot/A0A5J6INR6 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/67260:CP977_RS06270 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKY4 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/67260:CP977_RS09255 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJB0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/67260:CP977_RS13735 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILB9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS16340 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPR9 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine. http://togogenome.org/gene/67260:CP977_RS20780 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVG1 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/67260:CP977_RS03365 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKA1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS14310 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXH4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS09155 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMF9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/67260:CP977_RS05050 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRX5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MurCDEF family. MurT subfamily.|||Forms a heterodimer with GatD.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue. http://togogenome.org/gene/67260:CP977_RS25425 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS81 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/67260:CP977_RS23705 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/67260:CP977_RS29575 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUA9 ^@ Subunit ^@ Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/67260:CP977_RS09290 ^@ http://purl.uniprot.org/uniprot/A0A5J6IU79 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/67260:CP977_RS09710 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQD0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Membrane|||Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). http://togogenome.org/gene/67260:CP977_RS13480 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQD1 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/67260:CP977_RS24020 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITB2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.|||Homodimer.|||Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. http://togogenome.org/gene/67260:CP977_RS22690 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/67260:CP977_RS24170 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS15765 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQI2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/67260:CP977_RS08055 ^@ http://purl.uniprot.org/uniprot/A0A5J6IIP1 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/67260:CP977_RS31345 ^@ http://purl.uniprot.org/uniprot/A0A5J6J139 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/67260:CP977_RS32470 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZR8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS06370 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHV8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/67260:CP977_RS19865 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISG2 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/67260:CP977_RS27335 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT81 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/67260:CP977_RS07940 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKM9 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS19745 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS29145 ^@ http://purl.uniprot.org/uniprot/A0A5J6IW22 ^@ Similarity|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Homohexamer. The oligomerization is ATP-dependent. http://togogenome.org/gene/67260:CP977_RS20245 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITU1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/67260:CP977_RS01545 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWN1 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/67260:CP977_RS17570 ^@ http://purl.uniprot.org/uniprot/A0A5J6IU08 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/67260:CP977_RS12965 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKS4 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/67260:CP977_RS07525 ^@ http://purl.uniprot.org/uniprot/A0A5J6IIJ8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS13310 ^@ http://purl.uniprot.org/uniprot/A0A5J6IW16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS07440 ^@ http://purl.uniprot.org/uniprot/A0A5J6II23 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS11585 ^@ http://purl.uniprot.org/uniprot/A0A5J6IK42 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS20180 ^@ http://purl.uniprot.org/uniprot/A0A5J6J0H5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/67260:CP977_RS16570 ^@ http://purl.uniprot.org/uniprot/A0A5J6IYN1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/67260:CP977_RS18770 ^@ http://purl.uniprot.org/uniprot/A0A5J6IYL0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS20445 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRP9 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/67260:CP977_RS14490 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILH8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS15505 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPE0 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/67260:CP977_RS14630 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQU3 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/67260:CP977_RS14555 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILQ5 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/67260:CP977_RS14955 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQZ1 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/67260:CP977_RS15085 ^@ http://purl.uniprot.org/uniprot/A0A5J6INY9 ^@ Cofactor|||Similarity ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit. http://togogenome.org/gene/67260:CP977_RS24485 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS35 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/67260:CP977_RS12215 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRI2 ^@ Function|||Similarity ^@ Belongs to the RecD family. RecD-like subfamily.|||DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity. http://togogenome.org/gene/67260:CP977_RS09195 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJ99 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/67260:CP977_RS20775 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRS7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/67260:CP977_RS05500 ^@ http://purl.uniprot.org/uniprot/A0A5J6IYC3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/67260:CP977_RS19065 ^@ http://purl.uniprot.org/uniprot/A0A5J6INJ6 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/67260:CP977_RS15885 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRK8 ^@ Similarity ^@ Belongs to the class-II DAHP synthase family. http://togogenome.org/gene/67260:CP977_RS26075 ^@ http://purl.uniprot.org/uniprot/A0A5J6J273 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/67260:CP977_RS09375 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMJ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS06855 ^@ http://purl.uniprot.org/uniprot/A0A5J6IK61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS25345 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EccB family.|||Membrane http://togogenome.org/gene/67260:CP977_RS21355 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS28 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/67260:CP977_RS13785 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILC9 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/67260:CP977_RS24990 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS05 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/67260:CP977_RS30210 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWD4 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/67260:CP977_RS26040 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISW1 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/67260:CP977_RS17120 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPZ5 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/67260:CP977_RS25370 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS71 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/67260:CP977_RS23670 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVQ5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS18420 ^@ http://purl.uniprot.org/uniprot/A0A5J6IN99 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/67260:CP977_RS17740 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZK2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/67260:CP977_RS30285 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUL2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS06595 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL44 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/67260:CP977_RS15140 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQ44 ^@ Similarity ^@ Belongs to the UbiD family. http://togogenome.org/gene/67260:CP977_RS08135 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL92 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/67260:CP977_RS23885 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT95 ^@ Subunit ^@ Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/67260:CP977_RS25590 ^@ http://purl.uniprot.org/uniprot/A0A5J6IU81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/67260:CP977_RS20845 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWV6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein S18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS27315 ^@ http://purl.uniprot.org/uniprot/A0A5J6IV04 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/67260:CP977_RS11780 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWB7 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/67260:CP977_RS03175 ^@ http://purl.uniprot.org/uniprot/A0A5J6IK75 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the zinc-containing alcohol dehydrogenase family.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/67260:CP977_RS10755 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILZ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS11615 ^@ http://purl.uniprot.org/uniprot/A0A5J6INL4 ^@ Similarity ^@ Belongs to the CDP-glycerol glycerophosphotransferase family. http://togogenome.org/gene/67260:CP977_RS21125 ^@ http://purl.uniprot.org/uniprot/A0A5J6IU84 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/67260:CP977_RS22135 ^@ http://purl.uniprot.org/uniprot/A0A5J6IR00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/67260:CP977_RS28655 ^@ http://purl.uniprot.org/uniprot/A0A5J6J4C2 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/67260:CP977_RS02295 ^@ http://purl.uniprot.org/uniprot/A0A5J6IR82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/67260:CP977_RS17455 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQB3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS15190 ^@ http://purl.uniprot.org/uniprot/A0A5J6IR87 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/67260:CP977_RS27155 ^@ http://purl.uniprot.org/uniprot/A0A5J6J3L9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/67260:CP977_RS20890 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISV8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/67260:CP977_RS12375 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKW2 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/67260:CP977_RS17920 ^@ http://purl.uniprot.org/uniprot/A0A5J6INF1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS12610 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL05 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS32895 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXK3 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/67260:CP977_RS06795 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/67260:CP977_RS23830 ^@ http://purl.uniprot.org/uniprot/A0A5J6J152 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/67260:CP977_RS25285 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXP5 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/67260:CP977_RS15845 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT56 ^@ Similarity ^@ Belongs to the DNA polymerase type-A family. http://togogenome.org/gene/67260:CP977_RS25280 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITS4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/67260:CP977_RS21250 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS10 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS08065 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILX1 ^@ Similarity ^@ Belongs to the UPF0098 family. http://togogenome.org/gene/67260:CP977_RS08295 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKU1 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/67260:CP977_RS18010 ^@ http://purl.uniprot.org/uniprot/A0A5J6IU85 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/67260:CP977_RS06210 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS20580 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZL9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/67260:CP977_RS17605 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISG7 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/67260:CP977_RS10915 ^@ http://purl.uniprot.org/uniprot/A0A5J6IP54 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 3 family.|||Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%, with an endo mode of action. In contrast to the majority of pectate lyases, displays high activity on highly methylated pectins.|||Secreted http://togogenome.org/gene/67260:CP977_RS08320 ^@ http://purl.uniprot.org/uniprot/A0A5J6IIG9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS19305 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS83 ^@ Function|||Similarity ^@ Belongs to the trehalose phosphatase family.|||Removes the phosphate from trehalose 6-phosphate to produce free trehalose. http://togogenome.org/gene/67260:CP977_RS24345 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITC4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/67260:CP977_RS15525 ^@ http://purl.uniprot.org/uniprot/A0A5J6IY33 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/67260:CP977_RS24165 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS07295 ^@ http://purl.uniprot.org/uniprot/A0A5J6IIB7 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS15735 ^@ http://purl.uniprot.org/uniprot/A0A5J6IM16 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/67260:CP977_RS20800 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPA2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/67260:CP977_RS16890 ^@ http://purl.uniprot.org/uniprot/A0A5J6IN42 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/67260:CP977_RS09585 ^@ http://purl.uniprot.org/uniprot/A0A5J6INJ9 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/67260:CP977_RS33020 ^@ http://purl.uniprot.org/uniprot/A0A5J6J679 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS09200 ^@ http://purl.uniprot.org/uniprot/A0A5J6INC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS27995 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISV3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/67260:CP977_RS11265 ^@ http://purl.uniprot.org/uniprot/A0A5J6INF5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of glycine to tRNA(Gly).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/67260:CP977_RS14395 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQQ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/67260:CP977_RS28010 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITU2 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/67260:CP977_RS23055 ^@ http://purl.uniprot.org/uniprot/A0A5J6IR39 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/67260:CP977_RS08170 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILY8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/67260:CP977_RS20025 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITQ3 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/67260:CP977_RS15195 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQ54 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS27680 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISR8 ^@ Subunit ^@ Homotetramer. http://togogenome.org/gene/67260:CP977_RS06310 ^@ http://purl.uniprot.org/uniprot/A0A5J6II02 ^@ Similarity ^@ Belongs to the ribonuclease N1/T1 family. http://togogenome.org/gene/67260:CP977_RS18790 ^@ http://purl.uniprot.org/uniprot/A0A5J6INR5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PstS family.|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/67260:CP977_RS24530 ^@ http://purl.uniprot.org/uniprot/A0A5J6J2G4 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/67260:CP977_RS05605 ^@ http://purl.uniprot.org/uniprot/A0A5J6IH46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS13575 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL94 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/67260:CP977_RS21485 ^@ http://purl.uniprot.org/uniprot/A0A5J6J135 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/67260:CP977_RS15635 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMC0 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/67260:CP977_RS03695 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWT5 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/67260:CP977_RS10180 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVI0 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS01430 ^@ http://purl.uniprot.org/uniprot/A0A5J6IFJ5 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS08765 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJ09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/67260:CP977_RS14090 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILI0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/67260:CP977_RS10620 ^@ http://purl.uniprot.org/uniprot/A0A5J6J314 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS33320 ^@ http://purl.uniprot.org/uniprot/A0A5J6IW03 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/67260:CP977_RS24065 ^@ http://purl.uniprot.org/uniprot/A0A5J6IX26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS20075 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPN0 ^@ Function|||Similarity ^@ Belongs to the chloramphenicol acetyltransferase family.|||This enzyme is an effector of chloramphenicol resistance in bacteria. http://togogenome.org/gene/67260:CP977_RS05455 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS19950 ^@ http://purl.uniprot.org/uniprot/A0A5J6J0E0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DtxR/MntR family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/67260:CP977_RS19365 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS93 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS23650 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQP1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/67260:CP977_RS25915 ^@ http://purl.uniprot.org/uniprot/A0A5J6J316 ^@ Similarity ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. http://togogenome.org/gene/67260:CP977_RS20565 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRN8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/67260:CP977_RS20540 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPU3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/67260:CP977_RS23860 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVT5 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/67260:CP977_RS24635 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUL9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/67260:CP977_RS11145 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKA6 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/67260:CP977_RS05920 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sbp family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS32370 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZQ4 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/67260:CP977_RS01710 ^@ http://purl.uniprot.org/uniprot/A0A5J6IIX0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/67260:CP977_RS19560 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZ55 ^@ Function|||Similarity ^@ Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.|||Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/67260:CP977_RS04200 ^@ http://purl.uniprot.org/uniprot/A0A5J6IIR6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/67260:CP977_RS24015 ^@ http://purl.uniprot.org/uniprot/A0A5J6IX16 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. TreS subfamily. http://togogenome.org/gene/67260:CP977_RS05155 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJX4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/67260:CP977_RS20495 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISR6 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/67260:CP977_RS26035 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISH1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Cytoplasm|||Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS28710 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT85 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endonuclease V family.|||Cytoplasm|||DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. http://togogenome.org/gene/67260:CP977_RS25965 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRX9 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidine kinase family.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS13205 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL37 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/67260:CP977_RS32555 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXE6 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/67260:CP977_RS06380 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL03 ^@ Similarity ^@ Belongs to the OMP decarboxylase family. Type 2 subfamily. http://togogenome.org/gene/67260:CP977_RS07395 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.|||Membrane http://togogenome.org/gene/67260:CP977_RS24850 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUQ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/67260:CP977_RS28525 ^@ http://purl.uniprot.org/uniprot/A0A5J6J4A0 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/67260:CP977_RS25520 ^@ http://purl.uniprot.org/uniprot/A0A5J6IV26 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS31685 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZF0 ^@ Function|||Similarity ^@ ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.|||Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. http://togogenome.org/gene/67260:CP977_RS11740 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMH1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/67260:CP977_RS15740 ^@ http://purl.uniprot.org/uniprot/A0A5J6IY72 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/67260:CP977_RS03170 ^@ http://purl.uniprot.org/uniprot/A0A5J6IGA8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.|||Homodimer. http://togogenome.org/gene/67260:CP977_RS06250 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITC0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS14000 ^@ http://purl.uniprot.org/uniprot/A0A5J6INU0 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/67260:CP977_RS22475 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQ10 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/67260:CP977_RS05915 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKS2 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/67260:CP977_RS08745 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZ48 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/67260:CP977_RS21965 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/67260:CP977_RS13280 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILB0 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF2.|||Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. http://togogenome.org/gene/67260:CP977_RS21245 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT17 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/67260:CP977_RS09400 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJ01 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/67260:CP977_RS20185 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPP6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/67260:CP977_RS22835 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXH7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS31125 ^@ http://purl.uniprot.org/uniprot/A0A5J6J5E3 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/67260:CP977_RS09520 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJI5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterioferritin family.|||Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/67260:CP977_RS28835 ^@ http://purl.uniprot.org/uniprot/A0A5J6IU96 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IPP isomerase type 1 family.|||Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS23090 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISW4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/67260:CP977_RS19345 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPA7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cell surface|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.|||capsule|||cell wall http://togogenome.org/gene/67260:CP977_RS25420 ^@ http://purl.uniprot.org/uniprot/A0A5J6J2T4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/67260:CP977_RS05460 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJB6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS09530 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMM2 ^@ Similarity ^@ Belongs to the class-II DAHP synthase family. http://togogenome.org/gene/67260:CP977_RS07305 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILF9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.|||Monomer. http://togogenome.org/gene/67260:CP977_RS15450 ^@ http://purl.uniprot.org/uniprot/A0A5J6IX14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS16930 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQ17 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/67260:CP977_RS01370 ^@ http://purl.uniprot.org/uniprot/A0A5J6IFI3 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/67260:CP977_RS05580 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKK9 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/67260:CP977_RS25125 ^@ http://purl.uniprot.org/uniprot/A0A5J6IU09 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS24135 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT90 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/67260:CP977_RS28165 ^@ http://purl.uniprot.org/uniprot/A0A5J6J432 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/67260:CP977_RS32890 ^@ http://purl.uniprot.org/uniprot/A0A5J6J1U2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/67260:CP977_RS25215 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISE5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/67260:CP977_RS18930 ^@ http://purl.uniprot.org/uniprot/A0A5J6IYN4 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/67260:CP977_RS17700 ^@ http://purl.uniprot.org/uniprot/A0A5J6INK3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS06055 ^@ http://purl.uniprot.org/uniprot/A0A5J6IN07 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LamB/PxpA family.|||Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.|||Forms a complex composed of PxpA, PxpB and PxpC. http://togogenome.org/gene/67260:CP977_RS05290 ^@ http://purl.uniprot.org/uniprot/A0A5J6IGZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/67260:CP977_RS27685 ^@ http://purl.uniprot.org/uniprot/A0A5J6J3U6 ^@ Similarity ^@ Belongs to the allantoicase family. http://togogenome.org/gene/67260:CP977_RS08305 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILC3 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/67260:CP977_RS10285 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.|||Membrane http://togogenome.org/gene/67260:CP977_RS27560 ^@ http://purl.uniprot.org/uniprot/A0A5J6IV41 ^@ Similarity ^@ Belongs to the catalase family. http://togogenome.org/gene/67260:CP977_RS19945 ^@ http://purl.uniprot.org/uniprot/A0A5J6INX1 ^@ Similarity ^@ Belongs to the UPF0309 family. http://togogenome.org/gene/67260:CP977_RS15400 ^@ http://purl.uniprot.org/uniprot/A0A5J6IM84 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/67260:CP977_RS20695 ^@ http://purl.uniprot.org/uniprot/A0A5J6IP88 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/67260:CP977_RS23560 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWU9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS22610 ^@ http://purl.uniprot.org/uniprot/A0A5J6IR66 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/67260:CP977_RS15905 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPL7 ^@ Cofactor|||Similarity ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit. http://togogenome.org/gene/67260:CP977_RS06885 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITP2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/67260:CP977_RS06640 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILZ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS20630 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRS9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/67260:CP977_RS15530 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMA4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/67260:CP977_RS32565 ^@ http://purl.uniprot.org/uniprot/A0A5J6IV29 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/67260:CP977_RS15610 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT19 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS29505 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITM4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/67260:CP977_RS07055 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/67260:CP977_RS04930 ^@ http://purl.uniprot.org/uniprot/A0A5J6IM31 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/67260:CP977_RS11685 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/67260:CP977_RS26510 ^@ http://purl.uniprot.org/uniprot/A0A5J6IX32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS16025 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXB0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS25005 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUT2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/67260:CP977_RS28730 ^@ http://purl.uniprot.org/uniprot/A0A5J6IY90 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS33620 ^@ http://purl.uniprot.org/uniprot/A0A5J6J494 ^@ Similarity ^@ Belongs to the peptidase S1 family. http://togogenome.org/gene/67260:CP977_RS17410 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMT6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS10245 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJW0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/67260:CP977_RS30535 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUZ1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/67260:CP977_RS06555 ^@ http://purl.uniprot.org/uniprot/A0A5J6INA2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/67260:CP977_RS32205 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXW8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gas vesicle protein type A family.|||Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.|||gas vesicle membrane http://togogenome.org/gene/67260:CP977_RS32140 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXW0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/67260:CP977_RS19040 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQS8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyltransferase group 1 family. MshA subfamily.|||Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.|||Homodimer. http://togogenome.org/gene/67260:CP977_RS13820 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS96 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS27990 ^@ http://purl.uniprot.org/uniprot/A0A5J6J3A7 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/67260:CP977_RS25010 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/67260:CP977_RS04265 ^@ http://purl.uniprot.org/uniprot/A0A5J6IK07 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/67260:CP977_RS08075 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS12115 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKF2 ^@ Function|||Similarity ^@ Belongs to the uricase family.|||Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. http://togogenome.org/gene/67260:CP977_RS23700 ^@ http://purl.uniprot.org/uniprot/A0A5J6J136 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/67260:CP977_RS02110 ^@ http://purl.uniprot.org/uniprot/A0A5J6III6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS08630 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUG8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Membrane http://togogenome.org/gene/67260:CP977_RS07180 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITT5 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/67260:CP977_RS27095 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISG8 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/67260:CP977_RS12370 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKR3 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/67260:CP977_RS05065 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHD3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS33450 ^@ http://purl.uniprot.org/uniprot/A0A5J6IY15 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/67260:CP977_RS26940 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS32950 ^@ http://purl.uniprot.org/uniprot/A0A5J6J1V2 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/67260:CP977_RS09705 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILJ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/67260:CP977_RS10075 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJR9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS16195 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITC6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS26050 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWV5 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/67260:CP977_RS15750 ^@ http://purl.uniprot.org/uniprot/A0A5J6IME0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/67260:CP977_RS32915 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVT6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS09360 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJF5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS14080 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILA7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/67260:CP977_RS20665 ^@ http://purl.uniprot.org/uniprot/A0A5J6IST4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/67260:CP977_RS21510 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS57 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS04195 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJZ8 ^@ Function|||Subcellular Location Annotation ^@ May play a structural or regulatory role in gas vesicle synthesis.|||Vesicle|||gas vesicle http://togogenome.org/gene/67260:CP977_RS20635 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZM8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/67260:CP977_RS16940 ^@ http://purl.uniprot.org/uniprot/A0A5J6IML5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS05055 ^@ http://purl.uniprot.org/uniprot/A0A5J6IGV0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CobB/CobQ family. GatD subfamily.|||Forms a heterodimer with MurT.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT. http://togogenome.org/gene/67260:CP977_RS24970 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITZ0 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/67260:CP977_RS13515 ^@ http://purl.uniprot.org/uniprot/A0A5J6IX43 ^@ Similarity ^@ Belongs to the cysteine dioxygenase family. http://togogenome.org/gene/67260:CP977_RS14145 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWF0 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/67260:CP977_RS11925 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRE4 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/67260:CP977_RS16290 ^@ http://purl.uniprot.org/uniprot/A0A5J6J743 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.|||Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family. http://togogenome.org/gene/67260:CP977_RS32815 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVR7 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS11675 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPI2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS18090 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQR6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS32500 ^@ http://purl.uniprot.org/uniprot/A0A5J6J5H5 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/67260:CP977_RS04405 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS09305 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJE1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/67260:CP977_RS21545 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQQ4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/67260:CP977_RS20275 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZH3 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/67260:CP977_RS12535 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVP6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/67260:CP977_RS05160 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRZ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.|||Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/67260:CP977_RS31745 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS09665 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILW6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS20230 ^@ http://purl.uniprot.org/uniprot/A0A5J6J0J0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/67260:CP977_RS19520 ^@ http://purl.uniprot.org/uniprot/A0A5J6J081 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/67260:CP977_RS07390 ^@ http://purl.uniprot.org/uniprot/A0A5J6II10 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS17745 ^@ http://purl.uniprot.org/uniprot/A0A5J6IYY6 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/67260:CP977_RS14410 ^@ http://purl.uniprot.org/uniprot/A0A5J6INN4 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/67260:CP977_RS27985 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVC0 ^@ Similarity ^@ Belongs to the glycosyltransferase 28 family. http://togogenome.org/gene/67260:CP977_RS11435 ^@ http://purl.uniprot.org/uniprot/A0A5J6INI6 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/67260:CP977_RS24550 ^@ http://purl.uniprot.org/uniprot/A0A5J6IW51 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/67260:CP977_RS08705 ^@ http://purl.uniprot.org/uniprot/A0A5J6IN34 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/67260:CP977_RS03970 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILH0 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/67260:CP977_RS15745 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS17185 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXW1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS05140 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKE7 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/67260:CP977_RS03750 ^@ http://purl.uniprot.org/uniprot/A0A5J6J0K8 ^@ Cofactor|||Similarity ^@ Belongs to the monomeric-type IDH family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/67260:CP977_RS29730 ^@ http://purl.uniprot.org/uniprot/A0A5J6J439 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the arabinose isomerase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of L-arabinose to L-ribulose. http://togogenome.org/gene/67260:CP977_RS13625 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILA1 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/67260:CP977_RS10050 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQG6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/67260:CP977_RS23355 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISX5 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/67260:CP977_RS31050 ^@ http://purl.uniprot.org/uniprot/A0A5J6J0Z7 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/67260:CP977_RS13995 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISC8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/67260:CP977_RS04105 ^@ http://purl.uniprot.org/uniprot/A0A5J6IGC1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS20480 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPT5 ^@ Similarity ^@ Belongs to the UPF0336 family. http://togogenome.org/gene/67260:CP977_RS20610 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITZ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/67260:CP977_RS12415 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKS0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS22840 ^@ http://purl.uniprot.org/uniprot/A0A5J6IR07 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/67260:CP977_RS06985 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILA5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/67260:CP977_RS18955 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS20865 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPZ3 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/67260:CP977_RS22010 ^@ http://purl.uniprot.org/uniprot/A0A5J6J1J0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. http://togogenome.org/gene/67260:CP977_RS24100 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRL0 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/67260:CP977_RS23210 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQC7 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).|||Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS11295 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWC6 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/67260:CP977_RS12020 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKE3 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/67260:CP977_RS02365 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJU9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS06785 ^@ http://purl.uniprot.org/uniprot/A0A5J6II26 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/67260:CP977_RS26305 ^@ http://purl.uniprot.org/uniprot/A0A5J6J2A8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/67260:CP977_RS01610 ^@ http://purl.uniprot.org/uniprot/A0A5J6IFU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/67260:CP977_RS13475 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILD7 ^@ Similarity ^@ Belongs to the PGI/PMI family. http://togogenome.org/gene/67260:CP977_RS29705 ^@ http://purl.uniprot.org/uniprot/A0A5J6IX49 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS23645 ^@ http://purl.uniprot.org/uniprot/A0A5J6J132 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/67260:CP977_RS18200 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQF3 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/67260:CP977_RS11940 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS13165 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQA0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/67260:CP977_RS27795 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITQ2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS09300 ^@ http://purl.uniprot.org/uniprot/A0A5J6IV03 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/67260:CP977_RS31130 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUY5 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS25255 ^@ http://purl.uniprot.org/uniprot/A0A5J6J2R2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/67260:CP977_RS05240 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHG0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/67260:CP977_RS20730 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVF0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/67260:CP977_RS21590 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQB5 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/67260:CP977_RS17540 ^@ http://purl.uniprot.org/uniprot/A0A5J6IN68 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/67260:CP977_RS05045 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJV5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/67260:CP977_RS25110 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUV4 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/67260:CP977_RS23695 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT71 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/67260:CP977_RS09865 ^@ http://purl.uniprot.org/uniprot/A0A5J6INP4 ^@ Function ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/67260:CP977_RS08580 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUF8 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily. http://togogenome.org/gene/67260:CP977_RS09205 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMG7 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/67260:CP977_RS14105 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPN2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PEPCase type 1 family.|||Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.|||Homotetramer. http://togogenome.org/gene/67260:CP977_RS16540 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPP9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Cell membrane|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS27735 ^@ http://purl.uniprot.org/uniprot/A0A5J6J3W1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS25145 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS28390 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT30 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/67260:CP977_RS23880 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWZ7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS28470 ^@ http://purl.uniprot.org/uniprot/A0A5J6J491 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS20745 ^@ http://purl.uniprot.org/uniprot/A0A5J6IP95 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/67260:CP977_RS24935 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/67260:CP977_RS24945 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWC2 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/67260:CP977_RS28645 ^@ http://purl.uniprot.org/uniprot/A0A5J6J3L1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS10990 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMI9 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/67260:CP977_RS22260 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQR2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/67260:CP977_RS18205 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS06620 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHM8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.|||Cell membrane|||Contains a di-nuclear catalytic Mg(2+) center.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/67260:CP977_RS07855 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITL2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS13550 ^@ http://purl.uniprot.org/uniprot/A0A5J6INM2 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/67260:CP977_RS28845 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWR2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS29400 ^@ http://purl.uniprot.org/uniprot/A0A5J6J7X9 ^@ Function ^@ The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/67260:CP977_RS29900 ^@ http://purl.uniprot.org/uniprot/A0A5J6J460 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0719 family.|||Membrane http://togogenome.org/gene/67260:CP977_RS26030 ^@ http://purl.uniprot.org/uniprot/A0A5J6J336 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS07995 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKP0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS03265 ^@ http://purl.uniprot.org/uniprot/A0A5J6IR23 ^@ Similarity ^@ Belongs to the CsoR family. http://togogenome.org/gene/67260:CP977_RS11400 ^@ http://purl.uniprot.org/uniprot/A0A5J6IV72 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase Z family.|||Binds 2 Zn(2+) ions.|||Homodimer.|||Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. http://togogenome.org/gene/67260:CP977_RS09030 ^@ http://purl.uniprot.org/uniprot/A0A5J6IIU2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 35 family. http://togogenome.org/gene/67260:CP977_RS25430 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISH2 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/67260:CP977_RS18805 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRZ0 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/67260:CP977_RS29570 ^@ http://purl.uniprot.org/uniprot/A0A5J6J4T1 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/67260:CP977_RS23675 ^@ http://purl.uniprot.org/uniprot/A0A5J6J7E9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS17445 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQ61 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/67260:CP977_RS06870 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKP2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/67260:CP977_RS24695 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXC8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/67260:CP977_RS05060 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISS2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS10910 ^@ http://purl.uniprot.org/uniprot/A0A5J6IK66 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/67260:CP977_RS24670 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRU7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS21520 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS89 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS29635 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS15040 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWV0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS25000 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWD1 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS28215 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVG0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS06520 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWZ2 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/67260:CP977_RS13520 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL85 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the CofD family.|||Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS24910 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXH0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/67260:CP977_RS06965 ^@ http://purl.uniprot.org/uniprot/A0A5J6IIA6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/67260:CP977_RS31545 ^@ http://purl.uniprot.org/uniprot/A0A5J6IV50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS23640 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT60 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/67260:CP977_RS30605 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWQ5 ^@ Similarity ^@ Belongs to the melC1 family. http://togogenome.org/gene/67260:CP977_RS31090 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZ62 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/67260:CP977_RS14085 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXD6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/67260:CP977_RS06565 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT02 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/67260:CP977_RS30670 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWK5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the methyltransferase superfamily. EgtD family.|||Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.|||Monomer. http://togogenome.org/gene/67260:CP977_RS20810 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPY7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS08740 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITZ7 ^@ Function|||Subcellular Location Annotation ^@ Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.|||Membrane http://togogenome.org/gene/67260:CP977_RS12540 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.|||Membrane http://togogenome.org/gene/67260:CP977_RS03165 ^@ http://purl.uniprot.org/uniprot/A0A5J6IGH8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/67260:CP977_RS07230 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITU7 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/67260:CP977_RS21330 ^@ http://purl.uniprot.org/uniprot/A0A5J6J105 ^@ Cofactor|||Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/67260:CP977_RS12310 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKQ3 ^@ Similarity ^@ Belongs to the carbamoyltransferase HypF family. http://togogenome.org/gene/67260:CP977_RS22460 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWA1 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/67260:CP977_RS08635 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJ28 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/67260:CP977_RS09190 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJC3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Involved in both the histidine and tryptophan biosynthetic pathways. http://togogenome.org/gene/67260:CP977_RS17580 ^@ http://purl.uniprot.org/uniprot/A0A5J6IY32 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/67260:CP977_RS04255 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKP5 ^@ Similarity ^@ Belongs to the terpene synthase family. http://togogenome.org/gene/67260:CP977_RS32300 ^@ http://purl.uniprot.org/uniprot/A0A5J6J5Y0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS21450 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT58 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS06550 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJU2 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/67260:CP977_RS03730 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILD0 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/67260:CP977_RS05335 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKH4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/67260:CP977_RS08685 ^@ http://purl.uniprot.org/uniprot/A0A5J6IIM8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/67260:CP977_RS08485 ^@ http://purl.uniprot.org/uniprot/A0A5J6IM40 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS22445 ^@ http://purl.uniprot.org/uniprot/A0A5J6IV30 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/67260:CP977_RS05620 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHH5 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/67260:CP977_RS02715 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKU8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS08175 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKR9 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/67260:CP977_RS24340 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUH8 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/67260:CP977_RS02830 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJD4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/67260:CP977_RS32690 ^@ http://purl.uniprot.org/uniprot/A0A5J6IW10 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/67260:CP977_RS20215 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRL2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/67260:CP977_RS16825 ^@ http://purl.uniprot.org/uniprot/A0A5J6IN32 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/67260:CP977_RS06530 ^@ http://purl.uniprot.org/uniprot/A0A5J6J0R4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/67260:CP977_RS20605 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQ43 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/67260:CP977_RS31335 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXU9 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the peroxidase family. Peroxidase/catalase subfamily.|||Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.|||Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS13045 ^@ http://purl.uniprot.org/uniprot/A0A5J6IP69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SsgA family.|||Cell septum http://togogenome.org/gene/67260:CP977_RS20195 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITT1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/67260:CP977_RS09470 ^@ http://purl.uniprot.org/uniprot/A0A5J6INI1 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/67260:CP977_RS07405 ^@ http://purl.uniprot.org/uniprot/A0A5J6IID4 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/67260:CP977_RS31420 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUJ4 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/67260:CP977_RS01175 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHE0 ^@ Similarity ^@ Belongs to the EccD/Snm4 family. http://togogenome.org/gene/67260:CP977_RS20190 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPX1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 30 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/67260:CP977_RS13200 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWZ3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS30705 ^@ http://purl.uniprot.org/uniprot/A0A5J6IYZ9 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/67260:CP977_RS31595 ^@ http://purl.uniprot.org/uniprot/A0A5J6J5L3 ^@ Similarity ^@ Belongs to the cyt1/cyt2 endotoxin family. http://togogenome.org/gene/67260:CP977_RS23715 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRF4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/67260:CP977_RS31980 ^@ http://purl.uniprot.org/uniprot/A0A5J6IY56 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/67260:CP977_RS08585 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJ17 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/67260:CP977_RS13060 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRW6 ^@ Cofactor|||Similarity ^@ Belongs to the 4HPPD family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/67260:CP977_RS11640 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMS9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/67260:CP977_RS28580 ^@ http://purl.uniprot.org/uniprot/A0A5J6IX88 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/67260:CP977_RS13620 ^@ http://purl.uniprot.org/uniprot/A0A5J6IX62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/67260:CP977_RS14225 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPP8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 39 family.|||Cell membrane|||Membrane|||Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. http://togogenome.org/gene/67260:CP977_RS29480 ^@ http://purl.uniprot.org/uniprot/A0A5J6IW77 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS25540 ^@ http://purl.uniprot.org/uniprot/A0A5J6J1Z2 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/67260:CP977_RS06425 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILW1 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/67260:CP977_RS20550 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQ32 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/67260:CP977_RS27755 ^@ http://purl.uniprot.org/uniprot/A0A5J6IW65 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/67260:CP977_RS22245 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPX0 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/67260:CP977_RS24435 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS25 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/67260:CP977_RS18940 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZZ9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/67260:CP977_RS20705 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPX2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/67260:CP977_RS16320 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPL2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF1 family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS21025 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZT8 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/67260:CP977_RS03900 ^@ http://purl.uniprot.org/uniprot/A0A5J6IIL8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS32180 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVR9 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/67260:CP977_RS05120 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISS9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/67260:CP977_RS25620 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISB3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/67260:CP977_RS22580 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWC0 ^@ Cofactor|||Function ^@ Binds 1 [3Fe-4S] cluster.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/67260:CP977_RS28860 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVR8 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/67260:CP977_RS25205 ^@ http://purl.uniprot.org/uniprot/A0A5J6J2Q4 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS31035 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZ52 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS12455 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMR6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS21380 ^@ http://purl.uniprot.org/uniprot/A0A5J6J117 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/67260:CP977_RS06245 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHG1 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/67260:CP977_RS15710 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQH3 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/67260:CP977_RS15790 ^@ http://purl.uniprot.org/uniprot/A0A5J6IX74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS05245 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHB2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/67260:CP977_RS12665 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL13 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/67260:CP977_RS27905 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXU5 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/67260:CP977_RS20415 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPS6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/67260:CP977_RS07900 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL53 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/67260:CP977_RS07925 ^@ http://purl.uniprot.org/uniprot/A0A5J6IIM2 ^@ Function|||Similarity ^@ Belongs to the AlaDH/PNT family.|||Catalyzes the reversible reductive amination of pyruvate to L-alanine. http://togogenome.org/gene/67260:CP977_RS26615 ^@ http://purl.uniprot.org/uniprot/A0A5J6IX52 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS28735 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWP1 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/67260:CP977_RS08000 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPC3 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/67260:CP977_RS01565 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKA7 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/67260:CP977_RS21765 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUR5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.|||Belongs to the MshB deacetylase family. Mca subfamily.|||Binds 1 zinc ion per subunit.|||Monomer. http://togogenome.org/gene/67260:CP977_RS25170 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITQ6 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/67260:CP977_RS19285 ^@ http://purl.uniprot.org/uniprot/A0A5J6J047 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/67260:CP977_RS20645 ^@ http://purl.uniprot.org/uniprot/A0A5J6J0Q2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/67260:CP977_RS21630 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPN6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/67260:CP977_RS24405 ^@ http://purl.uniprot.org/uniprot/A0A5J6IX87 ^@ Cofactor ^@ Binds 1 FAD per subunit. http://togogenome.org/gene/67260:CP977_RS10865 ^@ http://purl.uniprot.org/uniprot/A0A5J6IN80 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/67260:CP977_RS21335 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQ69 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/67260:CP977_RS22850 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVA6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS14305 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SsgA family.|||Cell septum http://togogenome.org/gene/67260:CP977_RS15690 ^@ http://purl.uniprot.org/uniprot/A0A5J6IY61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS22865 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWH5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS15665 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT28 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/67260:CP977_RS08950 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILM7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS05400 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL91 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/67260:CP977_RS07190 ^@ http://purl.uniprot.org/uniprot/A0A5J6II94 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.|||Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.|||The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group. http://togogenome.org/gene/67260:CP977_RS18350 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZT1 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/67260:CP977_RS23750 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWY1 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/67260:CP977_RS21005 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRX3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS04720 ^@ http://purl.uniprot.org/uniprot/A0A5J6IH78 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/67260:CP977_RS25735 ^@ http://purl.uniprot.org/uniprot/A0A5J6J216 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/67260:CP977_RS27900 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITR7 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/67260:CP977_RS01260 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQB9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/67260:CP977_RS11355 ^@ http://purl.uniprot.org/uniprot/A0A5J6IK03 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/67260:CP977_RS15360 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRB5 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/67260:CP977_RS09700 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMP6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with subunits I, II and III to form cytochrome c oxidase.|||Belongs to the cytochrome c oxidase bacterial subunit CtaF family.|||Cell membrane|||Membrane|||Part of cytochrome c oxidase, its function is unknown. http://togogenome.org/gene/67260:CP977_RS20970 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZS9 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/67260:CP977_RS23195 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS31550 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVG9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS25615 ^@ http://purl.uniprot.org/uniprot/A0A5J6J2W2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS22145 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITH8 ^@ Function|||Similarity|||Subunit ^@ Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.|||Belongs to the AhpD family.|||Homotrimer. http://togogenome.org/gene/67260:CP977_RS08780 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL29 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/67260:CP977_RS30970 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUV6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/67260:CP977_RS08600 ^@ http://purl.uniprot.org/uniprot/A0A5J6IM62 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/67260:CP977_RS04165 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRH0 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/67260:CP977_RS24010 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT69 ^@ Similarity|||Subunit ^@ Belongs to the aminoglycoside phosphotransferase family.|||Monomer. http://togogenome.org/gene/67260:CP977_RS09335 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQ70 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/67260:CP977_RS09330 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILD1 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/67260:CP977_RS11690 ^@ http://purl.uniprot.org/uniprot/A0A5J6IR98 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/67260:CP977_RS21690 ^@ http://purl.uniprot.org/uniprot/A0A5J6J043 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS22625 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITQ7 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/67260:CP977_RS11720 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKK6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/67260:CP977_RS05935 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/67260:CP977_RS11880 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVF5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/67260:CP977_RS31695 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXN1 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/67260:CP977_RS16910 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPV4 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/67260:CP977_RS13215 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQA8 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/67260:CP977_RS21755 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQI5 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/67260:CP977_RS06215 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKX5 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/67260:CP977_RS23105 ^@ http://purl.uniprot.org/uniprot/A0A5J6J1V0 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/67260:CP977_RS17525 ^@ http://purl.uniprot.org/uniprot/A0A5J6IY23 ^@ Similarity ^@ Belongs to the UPF0232 family. http://togogenome.org/gene/67260:CP977_RS04760 ^@ http://purl.uniprot.org/uniprot/A0A5J6IGP4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/67260:CP977_RS17645 ^@ http://purl.uniprot.org/uniprot/A0A5J6IN93 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/67260:CP977_RS09745 ^@ http://purl.uniprot.org/uniprot/A0A5J6INM3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 3 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS23820 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWY8 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/67260:CP977_RS15770 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ThrE exporter (TC 2.A.79) family.|||Membrane http://togogenome.org/gene/67260:CP977_RS21605 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT87 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/67260:CP977_RS25790 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXX0 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/67260:CP977_RS04595 ^@ http://purl.uniprot.org/uniprot/A0A5J6IGL0 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/67260:CP977_RS20710 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQ62 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/67260:CP977_RS06690 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SsgA family.|||Cell septum http://togogenome.org/gene/67260:CP977_RS23690 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWX0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/67260:CP977_RS25900 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUC6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/67260:CP977_RS08375 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUD1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS09070 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILP9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS25350 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S8 family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS20440 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVA2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/67260:CP977_RS19370 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQY1 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.|||Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.|||Homodimer.|||Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. http://togogenome.org/gene/67260:CP977_RS08210 ^@ http://purl.uniprot.org/uniprot/A0A5J6IIV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/67260:CP977_RS11645 ^@ http://purl.uniprot.org/uniprot/A0A5J6J333 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/67260:CP977_RS06840 ^@ http://purl.uniprot.org/uniprot/A0A5J6IM26 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS22240 ^@ http://purl.uniprot.org/uniprot/A0A5J6J0C7 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/67260:CP977_RS29510 ^@ http://purl.uniprot.org/uniprot/A0A5J6J4S2 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/67260:CP977_RS01560 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHJ6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/67260:CP977_RS24730 ^@ http://purl.uniprot.org/uniprot/A0A5J6IW82 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/67260:CP977_RS06900 ^@ http://purl.uniprot.org/uniprot/A0A5J6IM35 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 2 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/67260:CP977_RS28310 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVN3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS11470 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKD2 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/67260:CP977_RS17555 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISG0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/67260:CP977_RS19280 ^@ http://purl.uniprot.org/uniprot/A0A5J6INN0 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/67260:CP977_RS06585 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHZ7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/67260:CP977_RS11875 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMW8 ^@ Similarity ^@ Belongs to the allantoicase family. http://togogenome.org/gene/67260:CP977_RS24475 ^@ http://purl.uniprot.org/uniprot/A0A5J6J2E7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS07225 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHY0 ^@ Similarity|||Subunit ^@ Belongs to the AAA ATPase family.|||Homohexamer. Assembles into a hexameric ring structure. http://togogenome.org/gene/67260:CP977_RS29405 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUI6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/67260:CP977_RS08615 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS04345 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRK2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/67260:CP977_RS07155 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKA2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/67260:CP977_RS21140 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVM5 ^@ Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. http://togogenome.org/gene/67260:CP977_RS24885 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRY6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/67260:CP977_RS20940 ^@ http://purl.uniprot.org/uniprot/A0A5J6IU59 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/67260:CP977_RS20740 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZP6 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/67260:CP977_RS09180 ^@ http://purl.uniprot.org/uniprot/A0A5J6IIW5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/67260:CP977_RS32610 ^@ http://purl.uniprot.org/uniprot/A0A5J6J5J4 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/67260:CP977_RS22605 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQW6 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/67260:CP977_RS20685 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRU1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/67260:CP977_RS24355 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITH4 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/67260:CP977_RS28030 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZ80 ^@ Similarity ^@ Belongs to the glycosyltransferase 28 family. http://togogenome.org/gene/67260:CP977_RS02905 ^@ http://purl.uniprot.org/uniprot/A0A5J6IIW7 ^@ Function|||Similarity ^@ Belongs to the ectoine synthase family.|||Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant. http://togogenome.org/gene/67260:CP977_RS25780 ^@ http://purl.uniprot.org/uniprot/A0A5J6IV66 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/67260:CP977_RS28595 ^@ http://purl.uniprot.org/uniprot/A0A5J6J4B1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SsgA family.|||Cell septum http://togogenome.org/gene/67260:CP977_RS22515 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS21145 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS16 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/67260:CP977_RS27745 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITP3 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/67260:CP977_RS26535 ^@ http://purl.uniprot.org/uniprot/A0A5J6J1T4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS21070 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS08 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/67260:CP977_RS27500 ^@ http://purl.uniprot.org/uniprot/A0A5J6J7U4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS16640 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMZ8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS30445 ^@ http://purl.uniprot.org/uniprot/A0A5J6IU45 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/67260:CP977_RS28875 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS26910 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUX5 ^@ Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family. http://togogenome.org/gene/67260:CP977_RS08555 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS10145 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMW4 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/67260:CP977_RS04175 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS63 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/67260:CP977_RS28025 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVH8 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/67260:CP977_RS24350 ^@ http://purl.uniprot.org/uniprot/A0A5J6IX75 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS18190 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRQ0 ^@ Similarity ^@ Belongs to the CsoR family. http://togogenome.org/gene/67260:CP977_RS13775 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL55 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/67260:CP977_RS23035 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS13555 ^@ http://purl.uniprot.org/uniprot/A0A5J6IW54 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/67260:CP977_RS09920 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVC3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS20620 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRP7 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/67260:CP977_RS28425 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWJ1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/67260:CP977_RS21175 ^@ http://purl.uniprot.org/uniprot/A0A5J6IU93 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/67260:CP977_RS13510 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL07 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/67260:CP977_RS05590 ^@ http://purl.uniprot.org/uniprot/A0A5J6IME4 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/67260:CP977_RS28055 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITM0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/67260:CP977_RS29840 ^@ http://purl.uniprot.org/uniprot/A0A5J6J454 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family.|||Belongs to the acyl-CoA oxidase family. http://togogenome.org/gene/67260:CP977_RS03335 ^@ http://purl.uniprot.org/uniprot/A0A5J6IR34 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS11105 ^@ http://purl.uniprot.org/uniprot/A0A5J6IM49 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/67260:CP977_RS31045 ^@ http://purl.uniprot.org/uniprot/A0A5J6IX57 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS31530 ^@ http://purl.uniprot.org/uniprot/A0A5J6J4Y2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS22545 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQV7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the MshB deacetylase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. http://togogenome.org/gene/67260:CP977_RS31290 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXG1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell inner membrane|||Cell membrane|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/67260:CP977_RS32480 ^@ http://purl.uniprot.org/uniprot/A0A5J6IY14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Membrane http://togogenome.org/gene/67260:CP977_RS10195 ^@ http://purl.uniprot.org/uniprot/A0A5J6INV0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/67260:CP977_RS28765 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT97 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/67260:CP977_RS27840 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITH5 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/67260:CP977_RS20595 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPV2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/67260:CP977_RS13850 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILD8 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/67260:CP977_RS29520 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUK6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/67260:CP977_RS20150 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISK3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnC family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/67260:CP977_RS18215 ^@ http://purl.uniprot.org/uniprot/A0A5J6IYE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Membrane http://togogenome.org/gene/67260:CP977_RS20805 ^@ http://purl.uniprot.org/uniprot/A0A5J6J0S6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/67260:CP977_RS07240 ^@ http://purl.uniprot.org/uniprot/A0A5J6IIA7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.|||Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.|||Homotetramer composed of a dimer of dimers. http://togogenome.org/gene/67260:CP977_RS09120 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILQ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/67260:CP977_RS25565 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/67260:CP977_RS15130 ^@ http://purl.uniprot.org/uniprot/A0A5J6IM33 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS24865 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS22025 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQX9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS22265 ^@ http://purl.uniprot.org/uniprot/A0A5J6IR17 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/67260:CP977_RS09510 ^@ http://purl.uniprot.org/uniprot/A0A5J6IV43 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/67260:CP977_RS13855 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILK5 ^@ Similarity ^@ Belongs to the transglycosylase family. Rpf subfamily. http://togogenome.org/gene/67260:CP977_RS06580 ^@ http://purl.uniprot.org/uniprot/A0A5J6II51 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/67260:CP977_RS30685 ^@ http://purl.uniprot.org/uniprot/A0A5J6J582 ^@ Function|||Similarity ^@ Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.|||Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine. http://togogenome.org/gene/67260:CP977_RS27825 ^@ http://purl.uniprot.org/uniprot/A0A5J6J375 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/67260:CP977_RS12190 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKN4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS29370 ^@ http://purl.uniprot.org/uniprot/A0A5J6J3Y8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS24245 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITF2 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/67260:CP977_RS13170 ^@ http://purl.uniprot.org/uniprot/A0A5J6IP80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS30640 ^@ http://purl.uniprot.org/uniprot/A0A5J6IV09 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/67260:CP977_RS02880 ^@ http://purl.uniprot.org/uniprot/A0A5J6IG58 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/67260:CP977_RS06410 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITF6 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/67260:CP977_RS14505 ^@ http://purl.uniprot.org/uniprot/A0A5J6IYT5 ^@ Similarity ^@ Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family. http://togogenome.org/gene/67260:CP977_RS06405 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHI8 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS32420 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZR1 ^@ Caution|||Similarity ^@ Belongs to the globin family. Two-domain flavohemoproteins subfamily.|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS03215 ^@ http://purl.uniprot.org/uniprot/A0A5J6IGI8 ^@ Similarity ^@ Belongs to the XFP family. http://togogenome.org/gene/67260:CP977_RS20815 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQ81 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/67260:CP977_RS21495 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQP4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS23800 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRS5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS08395 ^@ http://purl.uniprot.org/uniprot/A0A5J6IM30 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase S45 family.|||Binds 1 Ca(2+) ion per dimer. http://togogenome.org/gene/67260:CP977_RS06510 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHL0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/67260:CP977_RS09675 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJ51 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rieske iron-sulfur protein family.|||Cell membrane|||Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.|||Membrane http://togogenome.org/gene/67260:CP977_RS12795 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKX7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/67260:CP977_RS15910 ^@ http://purl.uniprot.org/uniprot/A0A5J6IX91 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/67260:CP977_RS02815 ^@ http://purl.uniprot.org/uniprot/A0A5J6IGC2 ^@ Similarity|||Subunit ^@ Belongs to the glutaminase family.|||Homotetramer. http://togogenome.org/gene/67260:CP977_RS18910 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS12 ^@ Caution|||Similarity ^@ Belongs to the nitrobindin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Lacks the conserved His residue that binds heme iron in the nitrobindin family. http://togogenome.org/gene/67260:CP977_RS26865 ^@ http://purl.uniprot.org/uniprot/A0A5J6IYG8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/67260:CP977_RS07990 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILW0 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/67260:CP977_RS18445 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRT8 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/67260:CP977_RS12315 ^@ http://purl.uniprot.org/uniprot/A0A5J6IKV3 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/67260:CP977_RS27590 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITC3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.|||Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).|||Homotetramer. http://togogenome.org/gene/67260:CP977_RS20135 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPP0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/67260:CP977_RS08530 ^@ http://purl.uniprot.org/uniprot/A0A5J6IIW9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/67260:CP977_RS06800 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS08185 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILA3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/67260:CP977_RS20920 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS24195 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITE0 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. http://togogenome.org/gene/67260:CP977_RS23100 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQB7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/67260:CP977_RS17680 ^@ http://purl.uniprot.org/uniprot/A0A5J6IY53 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/67260:CP977_RS06525 ^@ http://purl.uniprot.org/uniprot/A0A5J6II41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VKOR family.|||Membrane http://togogenome.org/gene/67260:CP977_RS24630 ^@ http://purl.uniprot.org/uniprot/A0A5J6IW63 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/67260:CP977_RS25065 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXK4 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS20535 ^@ http://purl.uniprot.org/uniprot/A0A5J6J0N6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/67260:CP977_RS17520 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQG7 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/67260:CP977_RS07210 ^@ http://purl.uniprot.org/uniprot/A0A5J6INK7 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.|||The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/67260:CP977_RS09635 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJK6 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/67260:CP977_RS03150 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWE7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS32225 ^@ http://purl.uniprot.org/uniprot/A0A5J6J5D1 ^@ Function|||Subcellular Location Annotation ^@ May play a structural or regulatory role in gas vesicle synthesis.|||Vesicle|||gas vesicle http://togogenome.org/gene/67260:CP977_RS12670 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQ26 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/67260:CP977_RS06325 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILQ0 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/67260:CP977_RS20915 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS03790 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILD9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/67260:CP977_RS05585 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJD6 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/67260:CP977_RS20160 ^@ http://purl.uniprot.org/uniprot/A0A5J6IV55 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). http://togogenome.org/gene/67260:CP977_RS10870 ^@ http://purl.uniprot.org/uniprot/A0A5J6IM06 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS20720 ^@ http://purl.uniprot.org/uniprot/A0A5J6IST9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/67260:CP977_RS04845 ^@ http://purl.uniprot.org/uniprot/A0A5J6IH95 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity ^@ Belongs to the nitrobindin family.|||Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.|||Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.|||Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS25710 ^@ http://purl.uniprot.org/uniprot/A0A5J6IV57 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/67260:CP977_RS29150 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZV0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/67260:CP977_RS25525 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/67260:CP977_RS29110 ^@ http://purl.uniprot.org/uniprot/A0A5J6J3U5 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/67260:CP977_RS27600 ^@ http://purl.uniprot.org/uniprot/A0A5J6IXN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/67260:CP977_RS29725 ^@ http://purl.uniprot.org/uniprot/A0A5J6IW64 ^@ Similarity ^@ Belongs to the ribulokinase family. http://togogenome.org/gene/67260:CP977_RS26290 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arginine deiminase family.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS30585 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUP5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/67260:CP977_RS27595 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITL6 ^@ Function|||Similarity ^@ Belongs to the uricase family.|||Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. http://togogenome.org/gene/67260:CP977_RS22490 ^@ http://purl.uniprot.org/uniprot/A0A5J6IR48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS27915 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVF7 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/67260:CP977_RS33610 ^@ http://purl.uniprot.org/uniprot/A0A5J6IVJ9 ^@ Similarity ^@ Belongs to the peptidase S51 family. http://togogenome.org/gene/67260:CP977_RS26555 ^@ http://purl.uniprot.org/uniprot/A0A5J6ISQ1 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/67260:CP977_RS20975 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPD5 ^@ Similarity ^@ Belongs to the IMPDH/GMPR family. http://togogenome.org/gene/67260:CP977_RS24830 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRX7 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/67260:CP977_RS17535 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZB9 ^@ Similarity ^@ Belongs to the 6-phosphogluconate dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS10925 ^@ http://purl.uniprot.org/uniprot/A0A5J6IN92 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/67260:CP977_RS31830 ^@ http://purl.uniprot.org/uniprot/A0A5J6J5Q0 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS15335 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWZ4 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/67260:CP977_RS12715 ^@ http://purl.uniprot.org/uniprot/A0A5J6IWS2 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. http://togogenome.org/gene/67260:CP977_RS20175 ^@ http://purl.uniprot.org/uniprot/A0A5J6IP07 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/67260:CP977_RS05600 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS32635 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZU1 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/67260:CP977_RS27845 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS23630 ^@ http://purl.uniprot.org/uniprot/A0A5J6IT18 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS24685 ^@ http://purl.uniprot.org/uniprot/A0A5J6IUM7 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/67260:CP977_RS28460 ^@ http://purl.uniprot.org/uniprot/A0A5J6J3I7 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/67260:CP977_RS15445 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPD7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS18825 ^@ http://purl.uniprot.org/uniprot/A0A5J6IYL8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the acetyltransferase family. MshD subfamily.|||Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/67260:CP977_RS19340 ^@ http://purl.uniprot.org/uniprot/A0A5J6J056 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/67260:CP977_RS20640 ^@ http://purl.uniprot.org/uniprot/A0A5J6IP79 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/67260:CP977_RS11455 ^@ http://purl.uniprot.org/uniprot/A0A5J6IV82 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/67260:CP977_RS16610 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITJ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/67260:CP977_RS31645 ^@ http://purl.uniprot.org/uniprot/A0A5J6J500 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/67260:CP977_RS19880 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRF7 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/67260:CP977_RS14545 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILJ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS22665 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQX7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer.|||In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.|||In the N-terminal section; belongs to the MIP18 family. http://togogenome.org/gene/67260:CP977_RS25210 ^@ http://purl.uniprot.org/uniprot/A0A5J6IS45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/67260:CP977_RS23515 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZY8 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/67260:CP977_RS07885 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILQ1 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/67260:CP977_RS07435 ^@ http://purl.uniprot.org/uniprot/A0A5J6ITE2 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/67260:CP977_RS19750 ^@ http://purl.uniprot.org/uniprot/A0A5J6IRA2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/67260:CP977_RS32430 ^@ http://purl.uniprot.org/uniprot/A0A5J6IY07 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/67260:CP977_RS03440 ^@ http://purl.uniprot.org/uniprot/A0A5J6IL76 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/67260:CP977_RS10830 ^@ http://purl.uniprot.org/uniprot/A0A5J6IJQ9 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/67260:CP977_RS05100 ^@ http://purl.uniprot.org/uniprot/A0A5J6IM61 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.|||Cytoplasm|||Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.|||Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/67260:CP977_RS23265 ^@ http://purl.uniprot.org/uniprot/A0A5J6J0W1 ^@ Similarity ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family. http://togogenome.org/gene/67260:CP977_RS21440 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQN2 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/67260:CP977_RS12560 ^@ http://purl.uniprot.org/uniprot/A0A5J6IQ11 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-to-5' exoribonuclease specific for small oligoribonucleotides.|||Belongs to the oligoribonuclease family.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS15340 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILU8 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/67260:CP977_RS08340 ^@ http://purl.uniprot.org/uniprot/A0A5J6IMX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane http://togogenome.org/gene/67260:CP977_RS06590 ^@ http://purl.uniprot.org/uniprot/A0A5J6ILY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/67260:CP977_RS12900 ^@ http://purl.uniprot.org/uniprot/A0A5J6INB6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GroES chaperonin family.|||Heptamer of 7 subunits arranged in a ring.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/67260:CP977_RS31940 ^@ http://purl.uniprot.org/uniprot/A0A5J6IX47 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrcB (TC 9.B.71) family.|||Cell membrane|||Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane http://togogenome.org/gene/67260:CP977_RS20690 ^@ http://purl.uniprot.org/uniprot/A0A5J6IZN5 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/67260:CP977_RS15775 ^@ http://purl.uniprot.org/uniprot/A0A5J6IPB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/67260:CP977_RS05670 ^@ http://purl.uniprot.org/uniprot/A0A5J6IHN6 ^@ Similarity ^@ Belongs to the thioesterase family.