http://togogenome.org/gene/633147:OLSU_RS04940 ^@ http://purl.uniprot.org/uniprot/E1QVE4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/633147:OLSU_RS03945 ^@ http://purl.uniprot.org/uniprot/E1QZT9 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/633147:OLSU_RS05190 ^@ http://purl.uniprot.org/uniprot/E1QVJ2 ^@ Similarity ^@ Belongs to the TelA family. http://togogenome.org/gene/633147:OLSU_RS04470 ^@ http://purl.uniprot.org/uniprot/E1R043 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS04835 ^@ http://purl.uniprot.org/uniprot/E1R0B2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.|||Homohexamer. Forms a ring that surrounds DNA.|||Membrane http://togogenome.org/gene/633147:OLSU_RS02005 ^@ http://purl.uniprot.org/uniprot/E1QYR4 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/633147:OLSU_RS08110 ^@ http://purl.uniprot.org/uniprot/E1QX70 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/633147:OLSU_RS04290 ^@ http://purl.uniprot.org/uniprot/E1R008 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/633147:OLSU_RS00645 ^@ http://purl.uniprot.org/uniprot/E1QXZ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS01515 ^@ http://purl.uniprot.org/uniprot/E1QYG3 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/633147:OLSU_RS03790 ^@ http://purl.uniprot.org/uniprot/E1QZR4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/633147:OLSU_RS09710 ^@ http://purl.uniprot.org/uniprot/E1QWP6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/633147:OLSU_RS07415 ^@ http://purl.uniprot.org/uniprot/E1QWT1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/633147:OLSU_RS05535 ^@ http://purl.uniprot.org/uniprot/E1QVQ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/633147:OLSU_RS00650 ^@ http://purl.uniprot.org/uniprot/E1QXZ4 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/633147:OLSU_RS04600 ^@ http://purl.uniprot.org/uniprot/E1R066 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably interacts with PlsX. http://togogenome.org/gene/633147:OLSU_RS05230 ^@ http://purl.uniprot.org/uniprot/E1QVK0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/633147:OLSU_RS02165 ^@ http://purl.uniprot.org/uniprot/E1QYU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/633147:OLSU_RS06450 ^@ http://purl.uniprot.org/uniprot/E1QW90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/633147:OLSU_RS01795 ^@ http://purl.uniprot.org/uniprot/E1QYM1 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/633147:OLSU_RS00730 ^@ http://purl.uniprot.org/uniprot/E1QY10 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/633147:OLSU_RS09060 ^@ http://purl.uniprot.org/uniprot/E1QZ56 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS08745 ^@ http://purl.uniprot.org/uniprot/E1QXI1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS02640 ^@ http://purl.uniprot.org/uniprot/E1QZ35 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/633147:OLSU_RS05740 ^@ http://purl.uniprot.org/uniprot/E1QVV0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS04590 ^@ http://purl.uniprot.org/uniprot/E1R064 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/633147:OLSU_RS08940 ^@ http://purl.uniprot.org/uniprot/E1QXL4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/633147:OLSU_RS06230 ^@ http://purl.uniprot.org/uniprot/E1QW50 ^@ Similarity ^@ Belongs to the BtpA family. http://togogenome.org/gene/633147:OLSU_RS04150 ^@ http://purl.uniprot.org/uniprot/E1QZY1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/633147:OLSU_RS03335 ^@ http://purl.uniprot.org/uniprot/E1QZH6 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/633147:OLSU_RS09015 ^@ http://purl.uniprot.org/uniprot/E1QYL5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS08095 ^@ http://purl.uniprot.org/uniprot/E1QX66 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/633147:OLSU_RS03990 ^@ http://purl.uniprot.org/uniprot/E1QZU9 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS08540 ^@ http://purl.uniprot.org/uniprot/E1QXE2 ^@ Similarity ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. http://togogenome.org/gene/633147:OLSU_RS05640 ^@ http://purl.uniprot.org/uniprot/E1QVT0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/633147:OLSU_RS07800 ^@ http://purl.uniprot.org/uniprot/E1QX08 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/633147:OLSU_RS06575 ^@ http://purl.uniprot.org/uniprot/E1QWB4 ^@ Similarity ^@ Belongs to the peptidase C69 family. http://togogenome.org/gene/633147:OLSU_RS08565 ^@ http://purl.uniprot.org/uniprot/E1QXE7 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/633147:OLSU_RS08575 ^@ http://purl.uniprot.org/uniprot/E1QXE9 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/633147:OLSU_RS01650 ^@ http://purl.uniprot.org/uniprot/E1QYJ0 ^@ Similarity ^@ Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/633147:OLSU_RS04685 ^@ http://purl.uniprot.org/uniprot/E1R082 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/633147:OLSU_RS08040 ^@ http://purl.uniprot.org/uniprot/E1QX55 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/633147:OLSU_RS05595 ^@ http://purl.uniprot.org/uniprot/E1QVS1 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/633147:OLSU_RS04720 ^@ http://purl.uniprot.org/uniprot/E1R089 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/633147:OLSU_RS03765 ^@ http://purl.uniprot.org/uniprot/E1QZQ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS06720 ^@ http://purl.uniprot.org/uniprot/E1QWE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/633147:OLSU_RS03390 ^@ http://purl.uniprot.org/uniprot/E1QZI7 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/633147:OLSU_RS04110 ^@ http://purl.uniprot.org/uniprot/E1QZX3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.|||Binds 1 Mn(2+) ion per subunit.|||Cytoplasm|||Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS01485 ^@ http://purl.uniprot.org/uniprot/E1QYF7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/633147:OLSU_RS02015 ^@ http://purl.uniprot.org/uniprot/E1QYR6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS03420 ^@ http://purl.uniprot.org/uniprot/E1QZJ3 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/633147:OLSU_RS00420 ^@ http://purl.uniprot.org/uniprot/E1QXU8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/633147:OLSU_RS00845 ^@ http://purl.uniprot.org/uniprot/E1QY30 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/633147:OLSU_RS07820 ^@ http://purl.uniprot.org/uniprot/E1QX11 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS03495 ^@ http://purl.uniprot.org/uniprot/E1QZK8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/633147:OLSU_RS08255 ^@ http://purl.uniprot.org/uniprot/E1QX94 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/633147:OLSU_RS08550 ^@ http://purl.uniprot.org/uniprot/E1QXE4 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/633147:OLSU_RS06750 ^@ http://purl.uniprot.org/uniprot/E1QWE9 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/633147:OLSU_RS07920 ^@ http://purl.uniprot.org/uniprot/E1QX31 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/633147:OLSU_RS07915 ^@ http://purl.uniprot.org/uniprot/E1QX30 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/633147:OLSU_RS09140 ^@ http://purl.uniprot.org/uniprot/E1QWE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/633147:OLSU_RS04365 ^@ http://purl.uniprot.org/uniprot/E1R023 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/633147:OLSU_RS00165 ^@ http://purl.uniprot.org/uniprot/E1QXP7 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/633147:OLSU_RS00960 ^@ http://purl.uniprot.org/uniprot/E1QY53 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/633147:OLSU_RS02650 ^@ http://purl.uniprot.org/uniprot/E1QZ37 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/633147:OLSU_RS01565 ^@ http://purl.uniprot.org/uniprot/E1QYH3 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/633147:OLSU_RS07205 ^@ http://purl.uniprot.org/uniprot/E1QWP1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/633147:OLSU_RS04825 ^@ http://purl.uniprot.org/uniprot/E1R0B0 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/633147:OLSU_RS05520 ^@ http://purl.uniprot.org/uniprot/E1QVQ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS06255 ^@ http://purl.uniprot.org/uniprot/E1QW55 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS05900 ^@ http://purl.uniprot.org/uniprot/E1QVY3 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/633147:OLSU_RS08690 ^@ http://purl.uniprot.org/uniprot/E1QXH0 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/633147:OLSU_RS05890 ^@ http://purl.uniprot.org/uniprot/E1QVY1 ^@ Similarity ^@ Belongs to the PhoU family.|||Belongs to the UPF0111 family. http://togogenome.org/gene/633147:OLSU_RS06350 ^@ http://purl.uniprot.org/uniprot/E1QW70 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/633147:OLSU_RS04935 ^@ http://purl.uniprot.org/uniprot/E1QVE3 ^@ Similarity ^@ Belongs to the RNA polymerase subunit omega family. http://togogenome.org/gene/633147:OLSU_RS00735 ^@ http://purl.uniprot.org/uniprot/E1QY11 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/633147:OLSU_RS04385 ^@ http://purl.uniprot.org/uniprot/E1R027 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/633147:OLSU_RS08120 ^@ http://purl.uniprot.org/uniprot/E1QX72 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/633147:OLSU_RS02625 ^@ http://purl.uniprot.org/uniprot/E1QZ32 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/633147:OLSU_RS05370 ^@ http://purl.uniprot.org/uniprot/E1QVM9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/633147:OLSU_RS07460 ^@ http://purl.uniprot.org/uniprot/E1QWU0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/633147:OLSU_RS04855 ^@ http://purl.uniprot.org/uniprot/E1R0B6 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/633147:OLSU_RS03185 ^@ http://purl.uniprot.org/uniprot/E1QZE7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS05015 ^@ http://purl.uniprot.org/uniprot/E1QVF8 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/633147:OLSU_RS04070 ^@ http://purl.uniprot.org/uniprot/E1QZW5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/633147:OLSU_RS05485 ^@ http://purl.uniprot.org/uniprot/E1QVP9 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/633147:OLSU_RS02120 ^@ http://purl.uniprot.org/uniprot/E1QYT6 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/633147:OLSU_RS02455 ^@ http://purl.uniprot.org/uniprot/E1QYZ8 ^@ Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family. http://togogenome.org/gene/633147:OLSU_RS07790 ^@ http://purl.uniprot.org/uniprot/E1QX06 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/633147:OLSU_RS04815 ^@ http://purl.uniprot.org/uniprot/E1R0A8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/633147:OLSU_RS01890 ^@ http://purl.uniprot.org/uniprot/E1QYP0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/633147:OLSU_RS03400 ^@ http://purl.uniprot.org/uniprot/E1QZI9 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/633147:OLSU_RS00025 ^@ http://purl.uniprot.org/uniprot/E1QXM4 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/633147:OLSU_RS02825 ^@ http://purl.uniprot.org/uniprot/E1QZ73 ^@ Similarity ^@ Belongs to the UPF0237 family. http://togogenome.org/gene/633147:OLSU_RS07910 ^@ http://purl.uniprot.org/uniprot/E1QX29 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/633147:OLSU_RS03890 ^@ http://purl.uniprot.org/uniprot/E1QZS9 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/633147:OLSU_RS08990 ^@ http://purl.uniprot.org/uniprot/E1QY48 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/633147:OLSU_RS02320 ^@ http://purl.uniprot.org/uniprot/E1QYX5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS03630 ^@ http://purl.uniprot.org/uniprot/E1QZN4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/633147:OLSU_RS00415 ^@ http://purl.uniprot.org/uniprot/E1QXU7 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/633147:OLSU_RS05760 ^@ http://purl.uniprot.org/uniprot/E1QVV5 ^@ Function|||Similarity ^@ Belongs to the DNA polymerase type-Y family.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/633147:OLSU_RS02085 ^@ http://purl.uniprot.org/uniprot/E1QYT0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/633147:OLSU_RS00345 ^@ http://purl.uniprot.org/uniprot/E1QXT3 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/633147:OLSU_RS04010 ^@ http://purl.uniprot.org/uniprot/E1QZV3 ^@ Similarity ^@ Belongs to the dihydrofolate reductase family. http://togogenome.org/gene/633147:OLSU_RS04780 ^@ http://purl.uniprot.org/uniprot/E1R0A1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/633147:OLSU_RS08560 ^@ http://purl.uniprot.org/uniprot/E1QXE6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/633147:OLSU_RS08115 ^@ http://purl.uniprot.org/uniprot/E1QX71 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/633147:OLSU_RS04255 ^@ http://purl.uniprot.org/uniprot/E1R001 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/633147:OLSU_RS05450 ^@ http://purl.uniprot.org/uniprot/E1QVP2 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/633147:OLSU_RS02790 ^@ http://purl.uniprot.org/uniprot/E1QZ65 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/633147:OLSU_RS04310 ^@ http://purl.uniprot.org/uniprot/E1R012 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/633147:OLSU_RS00520 ^@ http://purl.uniprot.org/uniprot/E1QXW7 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/633147:OLSU_RS03025 ^@ http://purl.uniprot.org/uniprot/E1QZB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS04475 ^@ http://purl.uniprot.org/uniprot/E1R044 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS00990 ^@ http://purl.uniprot.org/uniprot/E1QY59 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/633147:OLSU_RS07770 ^@ http://purl.uniprot.org/uniprot/E1QX02 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.|||Cell membrane|||Membrane|||Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. http://togogenome.org/gene/633147:OLSU_RS04885 ^@ http://purl.uniprot.org/uniprot/E1R0C2 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/633147:OLSU_RS00945 ^@ http://purl.uniprot.org/uniprot/E1QY50 ^@ Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family. http://togogenome.org/gene/633147:OLSU_RS07895 ^@ http://purl.uniprot.org/uniprot/E1QX26 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL17 family. http://togogenome.org/gene/633147:OLSU_RS04205 ^@ http://purl.uniprot.org/uniprot/E1QZZ2 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/633147:OLSU_RS05780 ^@ http://purl.uniprot.org/uniprot/E1QVV9 ^@ Similarity ^@ Belongs to the peptidase C69 family. http://togogenome.org/gene/633147:OLSU_RS03595 ^@ http://purl.uniprot.org/uniprot/E1QZM7 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily. http://togogenome.org/gene/633147:OLSU_RS07655 ^@ http://purl.uniprot.org/uniprot/E1QWX9 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/633147:OLSU_RS03605 ^@ http://purl.uniprot.org/uniprot/E1QZM9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/633147:OLSU_RS01520 ^@ http://purl.uniprot.org/uniprot/E1QYG4 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/633147:OLSU_RS00855 ^@ http://purl.uniprot.org/uniprot/E1QY32 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/633147:OLSU_RS04850 ^@ http://purl.uniprot.org/uniprot/E1R0B5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/633147:OLSU_RS08175 ^@ http://purl.uniprot.org/uniprot/E1QX78 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS00210 ^@ http://purl.uniprot.org/uniprot/E1QXQ6 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/633147:OLSU_RS05215 ^@ http://purl.uniprot.org/uniprot/E1QVJ7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/633147:OLSU_RS04605 ^@ http://purl.uniprot.org/uniprot/E1R067 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS04440 ^@ http://purl.uniprot.org/uniprot/E1R038 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/633147:OLSU_RS05590 ^@ http://purl.uniprot.org/uniprot/E1QVS0 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/633147:OLSU_RS04390 ^@ http://purl.uniprot.org/uniprot/E1R028 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/633147:OLSU_RS07980 ^@ http://purl.uniprot.org/uniprot/E1QX43 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/633147:OLSU_RS05175 ^@ http://purl.uniprot.org/uniprot/E1QVJ0 ^@ Similarity|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Homohexamer. The oligomerization is ATP-dependent. http://togogenome.org/gene/633147:OLSU_RS08860 ^@ http://purl.uniprot.org/uniprot/E1QXJ9 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/633147:OLSU_RS07795 ^@ http://purl.uniprot.org/uniprot/E1QX07 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/633147:OLSU_RS03405 ^@ http://purl.uniprot.org/uniprot/E1QZJ0 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/633147:OLSU_RS03600 ^@ http://purl.uniprot.org/uniprot/E1QZM8 ^@ Function|||Similarity ^@ Belongs to the QueH family.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). http://togogenome.org/gene/633147:OLSU_RS01435 ^@ http://purl.uniprot.org/uniprot/E1QYE7 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/633147:OLSU_RS02505 ^@ http://purl.uniprot.org/uniprot/E1QZ08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/633147:OLSU_RS08920 ^@ http://purl.uniprot.org/uniprot/E1QXL0 ^@ Similarity ^@ Belongs to the type II topoisomerase GyrB family. http://togogenome.org/gene/633147:OLSU_RS06445 ^@ http://purl.uniprot.org/uniprot/E1QW89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/633147:OLSU_RS04505 ^@ http://purl.uniprot.org/uniprot/E1R050 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/633147:OLSU_RS01010 ^@ http://purl.uniprot.org/uniprot/E1QY63 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/633147:OLSU_RS04025 ^@ http://purl.uniprot.org/uniprot/E1QZV6 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/633147:OLSU_RS08045 ^@ http://purl.uniprot.org/uniprot/E1QX56 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/633147:OLSU_RS00800 ^@ http://purl.uniprot.org/uniprot/E1QY21 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/633147:OLSU_RS00240 ^@ http://purl.uniprot.org/uniprot/E1QXR3 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. http://togogenome.org/gene/633147:OLSU_RS04430 ^@ http://purl.uniprot.org/uniprot/E1R036 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/633147:OLSU_RS00950 ^@ http://purl.uniprot.org/uniprot/E1QY51 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/633147:OLSU_RS07850 ^@ http://purl.uniprot.org/uniprot/E1QX17 ^@ Cofactor ^@ Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/633147:OLSU_RS02860 ^@ http://purl.uniprot.org/uniprot/E1QZ80 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/633147:OLSU_RS03365 ^@ http://purl.uniprot.org/uniprot/E1QZI2 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/633147:OLSU_RS00400 ^@ http://purl.uniprot.org/uniprot/E1QXU4 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/633147:OLSU_RS00075 ^@ http://purl.uniprot.org/uniprot/E1QXN2 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/633147:OLSU_RS07930 ^@ http://purl.uniprot.org/uniprot/E1QX33 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/633147:OLSU_RS00500 ^@ http://purl.uniprot.org/uniprot/E1QXW3 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/633147:OLSU_RS04315 ^@ http://purl.uniprot.org/uniprot/E1R013 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/633147:OLSU_RS04990 ^@ http://purl.uniprot.org/uniprot/E1QVF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/633147:OLSU_RS08610 ^@ http://purl.uniprot.org/uniprot/E1QXF4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/633147:OLSU_RS06725 ^@ http://purl.uniprot.org/uniprot/E1QWE4 ^@ Similarity ^@ Belongs to the CsoR family. http://togogenome.org/gene/633147:OLSU_RS03805 ^@ http://purl.uniprot.org/uniprot/E1QZR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/633147:OLSU_RS05570 ^@ http://purl.uniprot.org/uniprot/E1QVR6 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/633147:OLSU_RS00850 ^@ http://purl.uniprot.org/uniprot/E1QY31 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/633147:OLSU_RS00880 ^@ http://purl.uniprot.org/uniprot/E1QY37 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/633147:OLSU_RS08700 ^@ http://purl.uniprot.org/uniprot/E1QXH2 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/633147:OLSU_RS04840 ^@ http://purl.uniprot.org/uniprot/E1R0B3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/633147:OLSU_RS08415 ^@ http://purl.uniprot.org/uniprot/E1QXC0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/633147:OLSU_RS00440 ^@ http://purl.uniprot.org/uniprot/E1QXV3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/633147:OLSU_RS03160 ^@ http://purl.uniprot.org/uniprot/E1QZE2 ^@ Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family. http://togogenome.org/gene/633147:OLSU_RS04485 ^@ http://purl.uniprot.org/uniprot/E1R046 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/633147:OLSU_RS07735 ^@ http://purl.uniprot.org/uniprot/E1QWZ5 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/633147:OLSU_RS05510 ^@ http://purl.uniprot.org/uniprot/E1QVQ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS02465 ^@ http://purl.uniprot.org/uniprot/E1QZ00 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/633147:OLSU_RS00320 ^@ http://purl.uniprot.org/uniprot/E1QXS9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS04690 ^@ http://purl.uniprot.org/uniprot/E1R083 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/633147:OLSU_RS05120 ^@ http://purl.uniprot.org/uniprot/E1QVH9 ^@ Similarity ^@ Belongs to the KdgT transporter family. http://togogenome.org/gene/633147:OLSU_RS04230 ^@ http://purl.uniprot.org/uniprot/E1QZZ7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/633147:OLSU_RS05705 ^@ http://purl.uniprot.org/uniprot/E1QVU3 ^@ Similarity ^@ Belongs to the Vsr family. http://togogenome.org/gene/633147:OLSU_RS07165 ^@ http://purl.uniprot.org/uniprot/E1QWN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/633147:OLSU_RS01575 ^@ http://purl.uniprot.org/uniprot/E1QYH5 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/633147:OLSU_RS02955 ^@ http://purl.uniprot.org/uniprot/E1QZ99 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/633147:OLSU_RS02150 ^@ http://purl.uniprot.org/uniprot/E1QYU2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS04575 ^@ http://purl.uniprot.org/uniprot/E1R061 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/633147:OLSU_RS04445 ^@ http://purl.uniprot.org/uniprot/E1R039 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/633147:OLSU_RS02960 ^@ http://purl.uniprot.org/uniprot/E1QZA0 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/633147:OLSU_RS05380 ^@ http://purl.uniprot.org/uniprot/E1QVN1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/633147:OLSU_RS08430 ^@ http://purl.uniprot.org/uniprot/E1QXC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS04460 ^@ http://purl.uniprot.org/uniprot/E1R041 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/633147:OLSU_RS08270 ^@ http://purl.uniprot.org/uniprot/E1QX97 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS05630 ^@ http://purl.uniprot.org/uniprot/E1QVS8 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/633147:OLSU_RS07055 ^@ http://purl.uniprot.org/uniprot/E1QWL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS04260 ^@ http://purl.uniprot.org/uniprot/E1R002 ^@ Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/633147:OLSU_RS00545 ^@ http://purl.uniprot.org/uniprot/E1QXX2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/633147:OLSU_RS02325 ^@ http://purl.uniprot.org/uniprot/E1QYX6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS02375 ^@ http://purl.uniprot.org/uniprot/E1QYY2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS03780 ^@ http://purl.uniprot.org/uniprot/E1QZR2 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine. http://togogenome.org/gene/633147:OLSU_RS07320 ^@ http://purl.uniprot.org/uniprot/E1QWR2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/633147:OLSU_RS03325 ^@ http://purl.uniprot.org/uniprot/E1QZH4 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/633147:OLSU_RS06400 ^@ http://purl.uniprot.org/uniprot/E1QW80 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS03715 ^@ http://purl.uniprot.org/uniprot/E1QZP8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/633147:OLSU_RS07465 ^@ http://purl.uniprot.org/uniprot/E1QWU1 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/633147:OLSU_RS05130 ^@ http://purl.uniprot.org/uniprot/E1QVI1 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/633147:OLSU_RS00690 ^@ http://purl.uniprot.org/uniprot/E1QY02 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/633147:OLSU_RS00405 ^@ http://purl.uniprot.org/uniprot/E1QXU5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/633147:OLSU_RS00515 ^@ http://purl.uniprot.org/uniprot/E1QXW6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS00620 ^@ http://purl.uniprot.org/uniprot/E1QXY8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/633147:OLSU_RS08020 ^@ http://purl.uniprot.org/uniprot/E1QX51 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/633147:OLSU_RS01840 ^@ http://purl.uniprot.org/uniprot/E1QYN0 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/633147:OLSU_RS00955 ^@ http://purl.uniprot.org/uniprot/E1QY52 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cell surface|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.|||capsule|||cell wall http://togogenome.org/gene/633147:OLSU_RS06905 ^@ http://purl.uniprot.org/uniprot/E1QWI2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/633147:OLSU_RS03640 ^@ http://purl.uniprot.org/uniprot/E1QZN6 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/633147:OLSU_RS06375 ^@ http://purl.uniprot.org/uniprot/E1QW75 ^@ Function|||Similarity ^@ Belongs to the RapZ-like family.|||Displays ATPase and GTPase activities. http://togogenome.org/gene/633147:OLSU_RS05775 ^@ http://purl.uniprot.org/uniprot/E1QVV8 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/633147:OLSU_RS06655 ^@ http://purl.uniprot.org/uniprot/E1QWD0 ^@ Similarity ^@ Belongs to the UPF0597 family. http://togogenome.org/gene/633147:OLSU_RS06370 ^@ http://purl.uniprot.org/uniprot/E1QW74 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/633147:OLSU_RS05795 ^@ http://purl.uniprot.org/uniprot/E1QVW2 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/633147:OLSU_RS08585 ^@ http://purl.uniprot.org/uniprot/E1QXF1 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/633147:OLSU_RS04270 ^@ http://purl.uniprot.org/uniprot/E1R004 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/633147:OLSU_RS08870 ^@ http://purl.uniprot.org/uniprot/E1QXK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS01970 ^@ http://purl.uniprot.org/uniprot/E1QYQ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS03425 ^@ http://purl.uniprot.org/uniprot/E1QZJ4 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/633147:OLSU_RS00680 ^@ http://purl.uniprot.org/uniprot/E1QY00 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase A chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/633147:OLSU_RS06535 ^@ http://purl.uniprot.org/uniprot/E1QWA7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/633147:OLSU_RS04745 ^@ http://purl.uniprot.org/uniprot/E1R094 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/633147:OLSU_RS07840 ^@ http://purl.uniprot.org/uniprot/E1QX15 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.|||Cell inner membrane|||Cell membrane|||Mediates magnesium influx to the cytosol. http://togogenome.org/gene/633147:OLSU_RS04215 ^@ http://purl.uniprot.org/uniprot/E1QZZ4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/633147:OLSU_RS06335 ^@ http://purl.uniprot.org/uniprot/E1QW67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/633147:OLSU_RS05940 ^@ http://purl.uniprot.org/uniprot/E1QVZ1 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/633147:OLSU_RS05000 ^@ http://purl.uniprot.org/uniprot/E1QVF5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/633147:OLSU_RS03375 ^@ http://purl.uniprot.org/uniprot/E1QZI4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/633147:OLSU_RS05270 ^@ http://purl.uniprot.org/uniprot/E1QVK8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/633147:OLSU_RS05440 ^@ http://purl.uniprot.org/uniprot/E1QVP0 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/633147:OLSU_RS02810 ^@ http://purl.uniprot.org/uniprot/E1QZ70 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/633147:OLSU_RS06530 ^@ http://purl.uniprot.org/uniprot/E1QWA6 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/633147:OLSU_RS07885 ^@ http://purl.uniprot.org/uniprot/E1QX24 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS08130 ^@ http://purl.uniprot.org/uniprot/E1QX73 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/633147:OLSU_RS07975 ^@ http://purl.uniprot.org/uniprot/E1QX42 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/633147:OLSU_RS04705 ^@ http://purl.uniprot.org/uniprot/E1R086 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/633147:OLSU_RS04615 ^@ http://purl.uniprot.org/uniprot/E1R069 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. http://togogenome.org/gene/633147:OLSU_RS05610 ^@ http://purl.uniprot.org/uniprot/E1QVS4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS08390 ^@ http://purl.uniprot.org/uniprot/E1QXB6 ^@ Caution|||Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS00115 ^@ http://purl.uniprot.org/uniprot/E1QXN9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/633147:OLSU_RS02130 ^@ http://purl.uniprot.org/uniprot/E1QYT8 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20B family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/633147:OLSU_RS04750 ^@ http://purl.uniprot.org/uniprot/E1R095 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/633147:OLSU_RS00985 ^@ http://purl.uniprot.org/uniprot/E1QY58 ^@ Similarity ^@ Belongs to the PNP/UDP phosphorylase family. http://togogenome.org/gene/633147:OLSU_RS06900 ^@ http://purl.uniprot.org/uniprot/E1QWI1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS01445 ^@ http://purl.uniprot.org/uniprot/E1QYE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/633147:OLSU_RS00970 ^@ http://purl.uniprot.org/uniprot/E1QY55 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pseudouridine-5'-phosphate glycosidase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.|||Homotrimer. http://togogenome.org/gene/633147:OLSU_RS07705 ^@ http://purl.uniprot.org/uniprot/E1QWY9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/633147:OLSU_RS00785 ^@ http://purl.uniprot.org/uniprot/E1QY18 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/633147:OLSU_RS00395 ^@ http://purl.uniprot.org/uniprot/E1QXU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/633147:OLSU_RS06360 ^@ http://purl.uniprot.org/uniprot/E1QW72 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/633147:OLSU_RS05330 ^@ http://purl.uniprot.org/uniprot/E1QVM1 ^@ Similarity ^@ Belongs to the helicase family. RecG subfamily. http://togogenome.org/gene/633147:OLSU_RS02560 ^@ http://purl.uniprot.org/uniprot/E1QZ19 ^@ Activity Regulation|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/633147:OLSU_RS03740 ^@ http://purl.uniprot.org/uniprot/E1QZQ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS04465 ^@ http://purl.uniprot.org/uniprot/E1R042 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/633147:OLSU_RS03985 ^@ http://purl.uniprot.org/uniprot/E1QZU7 ^@ Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Homodimer. http://togogenome.org/gene/633147:OLSU_RS08680 ^@ http://purl.uniprot.org/uniprot/E1QXG8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS00585 ^@ http://purl.uniprot.org/uniprot/E1QXY0 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/633147:OLSU_RS07935 ^@ http://purl.uniprot.org/uniprot/E1QX34 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/633147:OLSU_RS05855 ^@ http://purl.uniprot.org/uniprot/E1QVX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/633147:OLSU_RS02665 ^@ http://purl.uniprot.org/uniprot/E1QZ40 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/633147:OLSU_RS08930 ^@ http://purl.uniprot.org/uniprot/E1QXL2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/633147:OLSU_RS04760 ^@ http://purl.uniprot.org/uniprot/E1R097 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/633147:OLSU_RS03865 ^@ http://purl.uniprot.org/uniprot/E1QZS6 ^@ Function|||Similarity ^@ Belongs to the carbohydrate kinase PfkB family.|||Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate. http://togogenome.org/gene/633147:OLSU_RS07355 ^@ http://purl.uniprot.org/uniprot/E1QWR9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS04300 ^@ http://purl.uniprot.org/uniprot/E1R010 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS03265 ^@ http://purl.uniprot.org/uniprot/E1QZG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/633147:OLSU_RS06515 ^@ http://purl.uniprot.org/uniprot/E1QWA3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/633147:OLSU_RS07780 ^@ http://purl.uniprot.org/uniprot/E1QX04 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS05265 ^@ http://purl.uniprot.org/uniprot/E1QVK7 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS03300 ^@ http://purl.uniprot.org/uniprot/E1QZG9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS04795 ^@ http://purl.uniprot.org/uniprot/E1R0A4 ^@ Function|||Similarity ^@ Belongs to the RNase Y family.|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/633147:OLSU_RS01380 ^@ http://purl.uniprot.org/uniprot/E1QYD4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS07950 ^@ http://purl.uniprot.org/uniprot/E1QX37 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/633147:OLSU_RS00460 ^@ http://purl.uniprot.org/uniprot/E1QXV7 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/633147:OLSU_RS06085 ^@ http://purl.uniprot.org/uniprot/E1QW19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/633147:OLSU_RS08730 ^@ http://purl.uniprot.org/uniprot/E1QXH8 ^@ Similarity ^@ Belongs to the agmatine deiminase family. http://togogenome.org/gene/633147:OLSU_RS08875 ^@ http://purl.uniprot.org/uniprot/E1QXK2 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS04000 ^@ http://purl.uniprot.org/uniprot/E1QZV1 ^@ Similarity ^@ In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.|||In the N-terminal section; belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/633147:OLSU_RS01025 ^@ http://purl.uniprot.org/uniprot/E1QY66 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/633147:OLSU_RS06925 ^@ http://purl.uniprot.org/uniprot/E1QWI4 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/633147:OLSU_RS04910 ^@ http://purl.uniprot.org/uniprot/E1QVD8 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/633147:OLSU_RS01005 ^@ http://purl.uniprot.org/uniprot/E1QY62 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS01040 ^@ http://purl.uniprot.org/uniprot/E1QY69 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/633147:OLSU_RS02040 ^@ http://purl.uniprot.org/uniprot/E1QYS1 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/633147:OLSU_RS04195 ^@ http://purl.uniprot.org/uniprot/E1QZZ0 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/633147:OLSU_RS06285 ^@ http://purl.uniprot.org/uniprot/E1QW60 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS04820 ^@ http://purl.uniprot.org/uniprot/E1R0A9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS07955 ^@ http://purl.uniprot.org/uniprot/E1QX38 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/633147:OLSU_RS04280 ^@ http://purl.uniprot.org/uniprot/E1R006 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/633147:OLSU_RS08010 ^@ http://purl.uniprot.org/uniprot/E1QX49 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/633147:OLSU_RS04170 ^@ http://purl.uniprot.org/uniprot/E1QZY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arginine deiminase family.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS06090 ^@ http://purl.uniprot.org/uniprot/E1QW20 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.|||Belongs to the DltC family.|||Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS03480 ^@ http://purl.uniprot.org/uniprot/E1QZK5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/633147:OLSU_RS07010 ^@ http://purl.uniprot.org/uniprot/E1QWK2 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/633147:OLSU_RS07715 ^@ http://purl.uniprot.org/uniprot/E1QWZ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/633147:OLSU_RS08005 ^@ http://purl.uniprot.org/uniprot/E1QX48 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/633147:OLSU_RS02965 ^@ http://purl.uniprot.org/uniprot/E1QZA1 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/633147:OLSU_RS03430 ^@ http://purl.uniprot.org/uniprot/E1QZJ5 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/633147:OLSU_RS07085 ^@ http://purl.uniprot.org/uniprot/E1QWL7 ^@ Similarity ^@ Belongs to the archaeal-type GPI family. http://togogenome.org/gene/633147:OLSU_RS04900 ^@ http://purl.uniprot.org/uniprot/E1QVD6 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/633147:OLSU_RS07760 ^@ http://purl.uniprot.org/uniprot/E1QX00 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS01620 ^@ http://purl.uniprot.org/uniprot/E1QYI4 ^@ Similarity ^@ Belongs to the EutP/PduV family. http://togogenome.org/gene/633147:OLSU_RS00870 ^@ http://purl.uniprot.org/uniprot/E1QY35 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/633147:OLSU_RS03895 ^@ http://purl.uniprot.org/uniprot/E1QZT0 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/633147:OLSU_RS03665 ^@ http://purl.uniprot.org/uniprot/E1QZN9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/633147:OLSU_RS00720 ^@ http://purl.uniprot.org/uniprot/E1QY08 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS00700 ^@ http://purl.uniprot.org/uniprot/E1QY04 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/633147:OLSU_RS03190 ^@ http://purl.uniprot.org/uniprot/E1QZE8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS08350 ^@ http://purl.uniprot.org/uniprot/E1QXB1 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/633147:OLSU_RS00860 ^@ http://purl.uniprot.org/uniprot/E1QY33 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS06195 ^@ http://purl.uniprot.org/uniprot/E1QW43 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/633147:OLSU_RS05365 ^@ http://purl.uniprot.org/uniprot/E1QVM8 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/633147:OLSU_RS02575 ^@ http://purl.uniprot.org/uniprot/E1QZ22 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/633147:OLSU_RS08075 ^@ http://purl.uniprot.org/uniprot/E1QX62 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/633147:OLSU_RS05145 ^@ http://purl.uniprot.org/uniprot/E1QVI4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS07905 ^@ http://purl.uniprot.org/uniprot/E1QX28 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/633147:OLSU_RS07345 ^@ http://purl.uniprot.org/uniprot/E1QWR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/633147:OLSU_RS08215 ^@ http://purl.uniprot.org/uniprot/E1QX86 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/633147:OLSU_RS08280 ^@ http://purl.uniprot.org/uniprot/E1QX99 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/633147:OLSU_RS01415 ^@ http://purl.uniprot.org/uniprot/E1QYE2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS06355 ^@ http://purl.uniprot.org/uniprot/E1QW71 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/633147:OLSU_RS00685 ^@ http://purl.uniprot.org/uniprot/E1QY01 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/633147:OLSU_RS04125 ^@ http://purl.uniprot.org/uniprot/E1QZX6 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/633147:OLSU_RS08315 ^@ http://purl.uniprot.org/uniprot/E1QXA6 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/633147:OLSU_RS08475 ^@ http://purl.uniprot.org/uniprot/E1QXD2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS00255 ^@ http://purl.uniprot.org/uniprot/E1QXR6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS02480 ^@ http://purl.uniprot.org/uniprot/E1QZ03 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/633147:OLSU_RS02445 ^@ http://purl.uniprot.org/uniprot/E1QYZ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS01665 ^@ http://purl.uniprot.org/uniprot/E1QYJ4 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/633147:OLSU_RS02315 ^@ http://purl.uniprot.org/uniprot/E1QYX4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/633147:OLSU_RS07105 ^@ http://purl.uniprot.org/uniprot/E1QWM2 ^@ Similarity ^@ Belongs to the PNP/MTAP phosphorylase family. http://togogenome.org/gene/633147:OLSU_RS08105 ^@ http://purl.uniprot.org/uniprot/E1QX69 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/633147:OLSU_RS04845 ^@ http://purl.uniprot.org/uniprot/E1R0B4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/633147:OLSU_RS04045 ^@ http://purl.uniprot.org/uniprot/E1QZW0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase D family.|||Cytoplasm|||Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides. http://togogenome.org/gene/633147:OLSU_RS02435 ^@ http://purl.uniprot.org/uniprot/E1QYZ4 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Non-allosteric. http://togogenome.org/gene/633147:OLSU_RS03415 ^@ http://purl.uniprot.org/uniprot/E1QZJ2 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/633147:OLSU_RS07350 ^@ http://purl.uniprot.org/uniprot/E1QWR8 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/633147:OLSU_RS07200 ^@ http://purl.uniprot.org/uniprot/E1QWP0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Belongs to the precorrin methyltransferase family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS05565 ^@ http://purl.uniprot.org/uniprot/E1QVR5 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS03960 ^@ http://purl.uniprot.org/uniprot/E1QZU2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/633147:OLSU_RS05410 ^@ http://purl.uniprot.org/uniprot/E1QVN7 ^@ Similarity ^@ Belongs to the RelB/DinJ antitoxin family. http://togogenome.org/gene/633147:OLSU_RS05910 ^@ http://purl.uniprot.org/uniprot/E1QVY5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/633147:OLSU_RS03900 ^@ http://purl.uniprot.org/uniprot/E1QZT1 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS08000 ^@ http://purl.uniprot.org/uniprot/E1QX47 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/633147:OLSU_RS07240 ^@ http://purl.uniprot.org/uniprot/E1QWP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/633147:OLSU_RS00760 ^@ http://purl.uniprot.org/uniprot/E1QY13 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/633147:OLSU_RS04480 ^@ http://purl.uniprot.org/uniprot/E1R045 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/633147:OLSU_RS08030 ^@ http://purl.uniprot.org/uniprot/E1QX53 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/633147:OLSU_RS01000 ^@ http://purl.uniprot.org/uniprot/E1QY61 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS08525 ^@ http://purl.uniprot.org/uniprot/E1QXD9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/633147:OLSU_RS06855 ^@ http://purl.uniprot.org/uniprot/E1QWH2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/633147:OLSU_RS06250 ^@ http://purl.uniprot.org/uniprot/E1QW54 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS04190 ^@ http://purl.uniprot.org/uniprot/E1QZY9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS03870 ^@ http://purl.uniprot.org/uniprot/E1QZS7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/633147:OLSU_RS05100 ^@ http://purl.uniprot.org/uniprot/E1QVH5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS01475 ^@ http://purl.uniprot.org/uniprot/E1QYF5 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/633147:OLSU_RS01560 ^@ http://purl.uniprot.org/uniprot/E1QYH2 ^@ Similarity ^@ Belongs to the PduL family. http://togogenome.org/gene/633147:OLSU_RS05475 ^@ http://purl.uniprot.org/uniprot/E1QVP7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS04865 ^@ http://purl.uniprot.org/uniprot/E1R0B8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Membrane http://togogenome.org/gene/633147:OLSU_RS02870 ^@ http://purl.uniprot.org/uniprot/E1QZ82 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/633147:OLSU_RS02750 ^@ http://purl.uniprot.org/uniprot/E1QZ57 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS01030 ^@ http://purl.uniprot.org/uniprot/E1QY67 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/633147:OLSU_RS04395 ^@ http://purl.uniprot.org/uniprot/E1R029 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/633147:OLSU_RS06295 ^@ http://purl.uniprot.org/uniprot/E1QW62 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS01875 ^@ http://purl.uniprot.org/uniprot/E1QYN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/633147:OLSU_RS08135 ^@ http://purl.uniprot.org/uniprot/E1QX74 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/633147:OLSU_RS02630 ^@ http://purl.uniprot.org/uniprot/E1QZ33 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/633147:OLSU_RS04015 ^@ http://purl.uniprot.org/uniprot/E1QZV4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS05250 ^@ http://purl.uniprot.org/uniprot/E1QVK4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/633147:OLSU_RS06870 ^@ http://purl.uniprot.org/uniprot/E1QWH5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS00250 ^@ http://purl.uniprot.org/uniprot/E1QXR5 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/633147:OLSU_RS08070 ^@ http://purl.uniprot.org/uniprot/E1QX61 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/633147:OLSU_RS05005 ^@ http://purl.uniprot.org/uniprot/E1QVF6 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/633147:OLSU_RS08035 ^@ http://purl.uniprot.org/uniprot/E1QX54 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/633147:OLSU_RS00875 ^@ http://purl.uniprot.org/uniprot/E1QY36 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD. http://togogenome.org/gene/633147:OLSU_RS01570 ^@ http://purl.uniprot.org/uniprot/E1QYH4 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/633147:OLSU_RS05545 ^@ http://purl.uniprot.org/uniprot/E1QVR1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS05245 ^@ http://purl.uniprot.org/uniprot/E1QVK3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/633147:OLSU_RS07945 ^@ http://purl.uniprot.org/uniprot/E1QX36 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/633147:OLSU_RS06200 ^@ http://purl.uniprot.org/uniprot/E1QW44 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated Cas9 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.|||Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.|||Monomer. Binds crRNA and tracrRNA. http://togogenome.org/gene/633147:OLSU_RS05030 ^@ http://purl.uniprot.org/uniprot/E1QVG1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/633147:OLSU_RS04370 ^@ http://purl.uniprot.org/uniprot/E1R024 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ A probable RNA-binding protein.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS01805 ^@ http://purl.uniprot.org/uniprot/E1QYM3 ^@ Function|||Similarity ^@ Belongs to the carbohydrate kinase PfkB family.|||Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate. http://togogenome.org/gene/633147:OLSU_RS07970 ^@ http://purl.uniprot.org/uniprot/E1QX41 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/633147:OLSU_RS06715 ^@ http://purl.uniprot.org/uniprot/E1QWE2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/633147:OLSU_RS02740 ^@ http://purl.uniprot.org/uniprot/E1QZ55 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/633147:OLSU_RS06490 ^@ http://purl.uniprot.org/uniprot/E1QW98 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/633147:OLSU_RS07445 ^@ http://purl.uniprot.org/uniprot/E1QWT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/633147:OLSU_RS03310 ^@ http://purl.uniprot.org/uniprot/E1QZH1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/633147:OLSU_RS05615 ^@ http://purl.uniprot.org/uniprot/E1QVS5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS08085 ^@ http://purl.uniprot.org/uniprot/E1QX64 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/633147:OLSU_RS01885 ^@ http://purl.uniprot.org/uniprot/E1QYN9 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/633147:OLSU_RS01535 ^@ http://purl.uniprot.org/uniprot/E1QYG7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the organic radical-activating enzymes family.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM). http://togogenome.org/gene/633147:OLSU_RS05320 ^@ http://purl.uniprot.org/uniprot/E1QVL9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/633147:OLSU_RS05210 ^@ http://purl.uniprot.org/uniprot/E1QVJ6 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/633147:OLSU_RS07410 ^@ http://purl.uniprot.org/uniprot/E1QWT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/633147:OLSU_RS07190 ^@ http://purl.uniprot.org/uniprot/E1QWN8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/633147:OLSU_RS00370 ^@ http://purl.uniprot.org/uniprot/E1QXT8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS03000 ^@ http://purl.uniprot.org/uniprot/E1QZA9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/633147:OLSU_RS05650 ^@ http://purl.uniprot.org/uniprot/E1QVT2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/633147:OLSU_RS04175 ^@ http://purl.uniprot.org/uniprot/E1QZY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS04770 ^@ http://purl.uniprot.org/uniprot/E1R099 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/633147:OLSU_RS07925 ^@ http://purl.uniprot.org/uniprot/E1QX32 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/633147:OLSU_RS05040 ^@ http://purl.uniprot.org/uniprot/E1QVG3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/633147:OLSU_RS06470 ^@ http://purl.uniprot.org/uniprot/E1QW94 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/633147:OLSU_RS02985 ^@ http://purl.uniprot.org/uniprot/E1QZA6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/633147:OLSU_RS08025 ^@ http://purl.uniprot.org/uniprot/E1QX52 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/633147:OLSU_RS05260 ^@ http://purl.uniprot.org/uniprot/E1QVK6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/633147:OLSU_RS04585 ^@ http://purl.uniprot.org/uniprot/E1R063 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS00570 ^@ http://purl.uniprot.org/uniprot/E1QXX7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS03245 ^@ http://purl.uniprot.org/uniprot/E1QZF9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the branched chain amino acid transporter family.|||Cell membrane|||Component of the transport system for branched-chain amino acids.|||Membrane http://togogenome.org/gene/633147:OLSU_RS05530 ^@ http://purl.uniprot.org/uniprot/E1QVQ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/633147:OLSU_RS06960 ^@ http://purl.uniprot.org/uniprot/E1QWJ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS07270 ^@ http://purl.uniprot.org/uniprot/E1QWQ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell inner membrane|||Cell membrane|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/633147:OLSU_RS06775 ^@ http://purl.uniprot.org/uniprot/E1QWF4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS04165 ^@ http://purl.uniprot.org/uniprot/E1QZY4 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/633147:OLSU_RS00330 ^@ http://purl.uniprot.org/uniprot/E1QXT1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/633147:OLSU_RS03915 ^@ http://purl.uniprot.org/uniprot/E1QZT3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/633147:OLSU_RS05480 ^@ http://purl.uniprot.org/uniprot/E1QVP8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/633147:OLSU_RS04350 ^@ http://purl.uniprot.org/uniprot/E1R020 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/633147:OLSU_RS03240 ^@ http://purl.uniprot.org/uniprot/E1QZF8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Cytoplasm|||Homodimer.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/633147:OLSU_RS07515 ^@ http://purl.uniprot.org/uniprot/E1QWV1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS04930 ^@ http://purl.uniprot.org/uniprot/E1QVE2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS05465 ^@ http://purl.uniprot.org/uniprot/E1QVP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DivIVA family.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS00635 ^@ http://purl.uniprot.org/uniprot/E1QXZ1 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/633147:OLSU_RS00485 ^@ http://purl.uniprot.org/uniprot/E1QXW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS03710 ^@ http://purl.uniprot.org/uniprot/E1QZP7 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/633147:OLSU_RS06505 ^@ http://purl.uniprot.org/uniprot/E1QWA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS00925 ^@ http://purl.uniprot.org/uniprot/E1QY46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS06955 ^@ http://purl.uniprot.org/uniprot/E1QWJ0 ^@ Similarity ^@ Belongs to the PhoU family.|||Belongs to the UPF0111 family. http://togogenome.org/gene/633147:OLSU_RS08535 ^@ http://purl.uniprot.org/uniprot/E1QXE1 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/633147:OLSU_RS08015 ^@ http://purl.uniprot.org/uniprot/E1QX50 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/633147:OLSU_RS08235 ^@ http://purl.uniprot.org/uniprot/E1QX90 ^@ Similarity ^@ Belongs to the ELP3 family. http://togogenome.org/gene/633147:OLSU_RS07810 ^@ http://purl.uniprot.org/uniprot/E1QX10 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/633147:OLSU_RS00140 ^@ http://purl.uniprot.org/uniprot/E1QXP2 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/633147:OLSU_RS05655 ^@ http://purl.uniprot.org/uniprot/E1QVT3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS01660 ^@ http://purl.uniprot.org/uniprot/E1QYJ3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/633147:OLSU_RS08725 ^@ http://purl.uniprot.org/uniprot/E1QXH7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/633147:OLSU_RS00865 ^@ http://purl.uniprot.org/uniprot/E1QY34 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/633147:OLSU_RS05905 ^@ http://purl.uniprot.org/uniprot/E1QVY4 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/633147:OLSU_RS04860 ^@ http://purl.uniprot.org/uniprot/E1R0B7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/633147:OLSU_RS04895 ^@ http://purl.uniprot.org/uniprot/E1R0C4 ^@ Similarity ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily. http://togogenome.org/gene/633147:OLSU_RS07325 ^@ http://purl.uniprot.org/uniprot/E1QWR3 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS00630 ^@ http://purl.uniprot.org/uniprot/E1QXZ0 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/633147:OLSU_RS08170 ^@ http://purl.uniprot.org/uniprot/E1QX77 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/633147:OLSU_RS02605 ^@ http://purl.uniprot.org/uniprot/E1QZ28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetokinase family.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS04375 ^@ http://purl.uniprot.org/uniprot/E1R025 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/633147:OLSU_RS00220 ^@ http://purl.uniprot.org/uniprot/E1QXQ8 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS06585 ^@ http://purl.uniprot.org/uniprot/E1QWB6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/633147:OLSU_RS05415 ^@ http://purl.uniprot.org/uniprot/E1QVN8 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/633147:OLSU_RS04145 ^@ http://purl.uniprot.org/uniprot/E1QZY0 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/633147:OLSU_RS05820 ^@ http://purl.uniprot.org/uniprot/E1QVW7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YejK family.|||nucleoid http://togogenome.org/gene/633147:OLSU_RS08530 ^@ http://purl.uniprot.org/uniprot/E1QXE0 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/633147:OLSU_RS05010 ^@ http://purl.uniprot.org/uniprot/E1QVF7 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/633147:OLSU_RS00765 ^@ http://purl.uniprot.org/uniprot/E1QY14 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF2.|||Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. http://togogenome.org/gene/633147:OLSU_RS08755 ^@ http://purl.uniprot.org/uniprot/E1QXI3 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/633147:OLSU_RS02415 ^@ http://purl.uniprot.org/uniprot/E1QYZ0 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/633147:OLSU_RS07900 ^@ http://purl.uniprot.org/uniprot/E1QX27 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/633147:OLSU_RS09440 ^@ http://purl.uniprot.org/uniprot/E1QXL6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/633147:OLSU_RS07545 ^@ http://purl.uniprot.org/uniprot/E1QWV7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS05580 ^@ http://purl.uniprot.org/uniprot/E1QVR8 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/633147:OLSU_RS01730 ^@ http://purl.uniprot.org/uniprot/E1QYK8 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/633147:OLSU_RS07965 ^@ http://purl.uniprot.org/uniprot/E1QX40 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/633147:OLSU_RS05085 ^@ http://purl.uniprot.org/uniprot/E1QVH2 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/633147:OLSU_RS05095 ^@ http://purl.uniprot.org/uniprot/E1QVH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetokinase family.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS07405 ^@ http://purl.uniprot.org/uniprot/E1QWS9 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/633147:OLSU_RS00100 ^@ http://purl.uniprot.org/uniprot/E1QXN7 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/633147:OLSU_RS07450 ^@ http://purl.uniprot.org/uniprot/E1QWT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/633147:OLSU_RS00410 ^@ http://purl.uniprot.org/uniprot/E1QXU6 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/633147:OLSU_RS04055 ^@ http://purl.uniprot.org/uniprot/E1QZW2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/633147:OLSU_RS03785 ^@ http://purl.uniprot.org/uniprot/E1QZR3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS08555 ^@ http://purl.uniprot.org/uniprot/E1QXE5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/633147:OLSU_RS05815 ^@ http://purl.uniprot.org/uniprot/E1QVW6 ^@ Similarity ^@ Belongs to the UPF0246 family. http://togogenome.org/gene/633147:OLSU_RS04725 ^@ http://purl.uniprot.org/uniprot/E1R090 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/633147:OLSU_RS07940 ^@ http://purl.uniprot.org/uniprot/E1QX35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/633147:OLSU_RS01490 ^@ http://purl.uniprot.org/uniprot/E1QYF8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS07865 ^@ http://purl.uniprot.org/uniprot/E1QX20 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS04345 ^@ http://purl.uniprot.org/uniprot/E1R019 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/633147:OLSU_RS00980 ^@ http://purl.uniprot.org/uniprot/E1QY57 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphopentomutase family.|||Binds 1 or 2 manganese ions.|||Cytoplasm|||Phosphotransfer between the C1 and C5 carbon atoms of pentose. http://togogenome.org/gene/633147:OLSU_RS00170 ^@ http://purl.uniprot.org/uniprot/E1QXP8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/633147:OLSU_RS03570 ^@ http://purl.uniprot.org/uniprot/E1QZM2 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/633147:OLSU_RS05275 ^@ http://purl.uniprot.org/uniprot/E1QVK9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/633147:OLSU_RS05490 ^@ http://purl.uniprot.org/uniprot/E1QVQ0 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/633147:OLSU_RS03340 ^@ http://purl.uniprot.org/uniprot/E1QZH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/633147:OLSU_RS00215 ^@ http://purl.uniprot.org/uniprot/E1QXQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS03625 ^@ http://purl.uniprot.org/uniprot/E1QZN3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/633147:OLSU_RS04405 ^@ http://purl.uniprot.org/uniprot/E1R031 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/633147:OLSU_RS07250 ^@ http://purl.uniprot.org/uniprot/E1QWP9 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/633147:OLSU_RS06415 ^@ http://purl.uniprot.org/uniprot/E1QW83 ^@ Function ^@ Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P). http://togogenome.org/gene/633147:OLSU_RS05470 ^@ http://purl.uniprot.org/uniprot/E1QVP6 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/633147:OLSU_RS08275 ^@ http://purl.uniprot.org/uniprot/E1QX98 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS03770 ^@ http://purl.uniprot.org/uniprot/E1QZR0 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/633147:OLSU_RS04540 ^@ http://purl.uniprot.org/uniprot/E1R054 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/633147:OLSU_RS02530 ^@ http://purl.uniprot.org/uniprot/E1QZ13 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/633147:OLSU_RS04965 ^@ http://purl.uniprot.org/uniprot/E1QVE9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/633147:OLSU_RS04220 ^@ http://purl.uniprot.org/uniprot/E1QZZ5 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS02035 ^@ http://purl.uniprot.org/uniprot/E1QYS0 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/633147:OLSU_RS08735 ^@ http://purl.uniprot.org/uniprot/E1QXH9 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. http://togogenome.org/gene/633147:OLSU_RS04330 ^@ http://purl.uniprot.org/uniprot/E1R016 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS06700 ^@ http://purl.uniprot.org/uniprot/E1QWD9 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/633147:OLSU_RS02160 ^@ http://purl.uniprot.org/uniprot/E1QYU4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 32 family.|||Cytoplasm|||Enables the bacterium to metabolize sucrose as a sole carbon source. http://togogenome.org/gene/633147:OLSU_RS03410 ^@ http://purl.uniprot.org/uniprot/E1QZJ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS06510 ^@ http://purl.uniprot.org/uniprot/E1QWA2 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/633147:OLSU_RS00780 ^@ http://purl.uniprot.org/uniprot/E1QY17 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/633147:OLSU_RS04805 ^@ http://purl.uniprot.org/uniprot/E1R0A6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS03195 ^@ http://purl.uniprot.org/uniprot/E1QZE9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/633147:OLSU_RS06130 ^@ http://purl.uniprot.org/uniprot/E1QW28 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS00840 ^@ http://purl.uniprot.org/uniprot/E1QY29 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/633147:OLSU_RS00200 ^@ http://purl.uniprot.org/uniprot/E1QXQ4 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/633147:OLSU_RS04730 ^@ http://purl.uniprot.org/uniprot/E1R091 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS07995 ^@ http://purl.uniprot.org/uniprot/E1QX46 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/633147:OLSU_RS07830 ^@ http://purl.uniprot.org/uniprot/E1QX13 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase C15 family.|||Cytoplasm|||Homotetramer.|||Removes 5-oxoproline from various penultimate amino acid residues except L-proline. http://togogenome.org/gene/633147:OLSU_RS08065 ^@ http://purl.uniprot.org/uniprot/E1QX60 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS00090 ^@ http://purl.uniprot.org/uniprot/E1QXN5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS05125 ^@ http://purl.uniprot.org/uniprot/E1QVI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS06605 ^@ http://purl.uniprot.org/uniprot/E1QWC0 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/633147:OLSU_RS05035 ^@ http://purl.uniprot.org/uniprot/E1QVG2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/633147:OLSU_RS06710 ^@ http://purl.uniprot.org/uniprot/E1QWE1 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS07720 ^@ http://purl.uniprot.org/uniprot/E1QWZ2 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/633147:OLSU_RS00235 ^@ http://purl.uniprot.org/uniprot/E1QXR2 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/633147:OLSU_RS06020 ^@ http://purl.uniprot.org/uniprot/E1QW06 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/633147:OLSU_RS03775 ^@ http://purl.uniprot.org/uniprot/E1QZR1 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/633147:OLSU_RS00160 ^@ http://purl.uniprot.org/uniprot/E1QXP6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/633147:OLSU_RS08670 ^@ http://purl.uniprot.org/uniprot/E1QXG6 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. http://togogenome.org/gene/633147:OLSU_RS06935 ^@ http://purl.uniprot.org/uniprot/E1QWI6 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/633147:OLSU_RS00560 ^@ http://purl.uniprot.org/uniprot/E1QXX5 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/633147:OLSU_RS06825 ^@ http://purl.uniprot.org/uniprot/E1QWG5 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/633147:OLSU_RS05345 ^@ http://purl.uniprot.org/uniprot/E1QVM4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/633147:OLSU_RS05660 ^@ http://purl.uniprot.org/uniprot/E1QVT4 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS03055 ^@ http://purl.uniprot.org/uniprot/E1QZC0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CobB/CobQ family. GatD subfamily.|||Forms a heterodimer with MurT.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT. http://togogenome.org/gene/633147:OLSU_RS06365 ^@ http://purl.uniprot.org/uniprot/E1QW73 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/633147:OLSU_RS04970 ^@ http://purl.uniprot.org/uniprot/E1QVF0 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/633147:OLSU_RS01755 ^@ http://purl.uniprot.org/uniprot/E1QYL3 ^@ Similarity ^@ Belongs to the polypeptide deformylase family. http://togogenome.org/gene/633147:OLSU_RS04920 ^@ http://purl.uniprot.org/uniprot/E1QVE0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS05155 ^@ http://purl.uniprot.org/uniprot/E1QVI6 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/633147:OLSU_RS03060 ^@ http://purl.uniprot.org/uniprot/E1QZC1 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/633147:OLSU_RS06495 ^@ http://purl.uniprot.org/uniprot/E1QW99 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS04380 ^@ http://purl.uniprot.org/uniprot/E1R026 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/633147:OLSU_RS02140 ^@ http://purl.uniprot.org/uniprot/E1QYU0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/633147:OLSU_RS05255 ^@ http://purl.uniprot.org/uniprot/E1QVK5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/633147:OLSU_RS04435 ^@ http://purl.uniprot.org/uniprot/E1R037 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/633147:OLSU_RS07960 ^@ http://purl.uniprot.org/uniprot/E1QX39 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/633147:OLSU_RS02695 ^@ http://purl.uniprot.org/uniprot/E1QZ46 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/633147:OLSU_RS06990 ^@ http://purl.uniprot.org/uniprot/E1QWJ8 ^@ Similarity ^@ Belongs to the BtpA family. http://togogenome.org/gene/633147:OLSU_RS09120 ^@ http://purl.uniprot.org/uniprot/E1QW33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM86 family.|||Membrane http://togogenome.org/gene/633147:OLSU_RS05600 ^@ http://purl.uniprot.org/uniprot/E1QVS2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/633147:OLSU_RS04595 ^@ http://purl.uniprot.org/uniprot/E1R065 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/633147:OLSU_RS07490 ^@ http://purl.uniprot.org/uniprot/E1QWU6 ^@ Function|||Similarity ^@ Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/633147:OLSU_RS03315 ^@ http://purl.uniprot.org/uniprot/E1QZH2 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/633147:OLSU_RS08605 ^@ http://purl.uniprot.org/uniprot/E1QXF3 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/633147:OLSU_RS03320 ^@ http://purl.uniprot.org/uniprot/E1QZH3 ^@ Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family. http://togogenome.org/gene/633147:OLSU_RS06635 ^@ http://purl.uniprot.org/uniprot/E1QWC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/633147:OLSU_RS05715 ^@ http://purl.uniprot.org/uniprot/E1QVU5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS01320 ^@ http://purl.uniprot.org/uniprot/E1QYC2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/633147:OLSU_RS02420 ^@ http://purl.uniprot.org/uniprot/E1QYZ1 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/633147:OLSU_RS01825 ^@ http://purl.uniprot.org/uniprot/E1QYM7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/633147:OLSU_RS00715 ^@ http://purl.uniprot.org/uniprot/E1QY07 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/633147:OLSU_RS04130 ^@ http://purl.uniprot.org/uniprot/E1QZX7 ^@ Similarity ^@ Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family. http://togogenome.org/gene/633147:OLSU_RS04030 ^@ http://purl.uniprot.org/uniprot/E1QZV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acyl-ACP thioesterase family.|||chloroplast http://togogenome.org/gene/633147:OLSU_RS05930 ^@ http://purl.uniprot.org/uniprot/E1QVY9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/633147:OLSU_RS01240 ^@ http://purl.uniprot.org/uniprot/E1QYA8 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/633147:OLSU_RS02715 ^@ http://purl.uniprot.org/uniprot/E1QZ50 ^@ Similarity|||Subunit ^@ Belongs to the pyruvate kinase family.|||Homotetramer. http://togogenome.org/gene/633147:OLSU_RS01200 ^@ http://purl.uniprot.org/uniprot/E1QYA0 ^@ Similarity ^@ Belongs to the RelB/DinJ antitoxin family. http://togogenome.org/gene/633147:OLSU_RS05885 ^@ http://purl.uniprot.org/uniprot/E1QVY0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS02410 ^@ http://purl.uniprot.org/uniprot/E1QYY9 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/633147:OLSU_RS01090 ^@ http://purl.uniprot.org/uniprot/E1QY78 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/633147:OLSU_RS00300 ^@ http://purl.uniprot.org/uniprot/E1QXS5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS05340 ^@ http://purl.uniprot.org/uniprot/E1QVM3 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/633147:OLSU_RS05375 ^@ http://purl.uniprot.org/uniprot/E1QVN0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS08665 ^@ http://purl.uniprot.org/uniprot/E1QXG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/633147:OLSU_RS05445 ^@ http://purl.uniprot.org/uniprot/E1QVP1 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/633147:OLSU_RS06425 ^@ http://purl.uniprot.org/uniprot/E1QW85 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/633147:OLSU_RS03675 ^@ http://purl.uniprot.org/uniprot/E1QZP1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/633147:OLSU_RS06680 ^@ http://purl.uniprot.org/uniprot/E1QWD5 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/633147:OLSU_RS02610 ^@ http://purl.uniprot.org/uniprot/E1QZ29 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS00030 ^@ http://purl.uniprot.org/uniprot/E1QXM5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS03295 ^@ http://purl.uniprot.org/uniprot/E1QZG8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/633147:OLSU_RS05555 ^@ http://purl.uniprot.org/uniprot/E1QVR3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/633147:OLSU_RS04335 ^@ http://purl.uniprot.org/uniprot/E1R017 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/633147:OLSU_RS02720 ^@ http://purl.uniprot.org/uniprot/E1QZ51 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/633147:OLSU_RS02125 ^@ http://purl.uniprot.org/uniprot/E1QYT7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably interacts with PlsX. http://togogenome.org/gene/633147:OLSU_RS08060 ^@ http://purl.uniprot.org/uniprot/E1QX59 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/633147:OLSU_RS08210 ^@ http://purl.uniprot.org/uniprot/E1QX85 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/633147:OLSU_RS05220 ^@ http://purl.uniprot.org/uniprot/E1QVJ8 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/633147:OLSU_RS01305 ^@ http://purl.uniprot.org/uniprot/E1QYB9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS00060 ^@ http://purl.uniprot.org/uniprot/E1QXN0 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/633147:OLSU_RS08410 ^@ http://purl.uniprot.org/uniprot/E1QXB9 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS05560 ^@ http://purl.uniprot.org/uniprot/E1QVR4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/633147:OLSU_RS06010 ^@ http://purl.uniprot.org/uniprot/E1QW04 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS01530 ^@ http://purl.uniprot.org/uniprot/E1QYG6 ^@ Function|||PTM|||Similarity ^@ Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily.|||Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde.|||Requires the activating protein CutD to generate the key active site glycyl radical on Gly-822 that is involved in catalysis. http://togogenome.org/gene/633147:OLSU_RS08100 ^@ http://purl.uniprot.org/uniprot/E1QX67 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/633147:OLSU_RS02655 ^@ http://purl.uniprot.org/uniprot/E1QZ38 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/633147:OLSU_RS07290 ^@ http://purl.uniprot.org/uniprot/E1QWQ6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Binds 1 Fe cation per subunit.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/633147:OLSU_RS03735 ^@ http://purl.uniprot.org/uniprot/E1QZQ3 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/633147:OLSU_RS05075 ^@ http://purl.uniprot.org/uniprot/E1QVH0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS05400 ^@ http://purl.uniprot.org/uniprot/E1QVN5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/633147:OLSU_RS03670 ^@ http://purl.uniprot.org/uniprot/E1QZP0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/633147:OLSU_RS02490 ^@ http://purl.uniprot.org/uniprot/E1QZ05 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/633147:OLSU_RS01880 ^@ http://purl.uniprot.org/uniprot/E1QYN8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/633147:OLSU_RS07305 ^@ http://purl.uniprot.org/uniprot/E1QWQ9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IPP isomerase type 1 family.|||Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS05025 ^@ http://purl.uniprot.org/uniprot/E1QVG0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/633147:OLSU_RS06125 ^@ http://purl.uniprot.org/uniprot/E1QW27 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS00540 ^@ http://purl.uniprot.org/uniprot/E1QXX1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS06340 ^@ http://purl.uniprot.org/uniprot/E1QW68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/633147:OLSU_RS04210 ^@ http://purl.uniprot.org/uniprot/E1QZZ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/633147:OLSU_RS05525 ^@ http://purl.uniprot.org/uniprot/E1QVQ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS06390 ^@ http://purl.uniprot.org/uniprot/E1QW78 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/633147:OLSU_RS08955 ^@ http://purl.uniprot.org/uniprot/E1QXL9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/633147:OLSU_RS00340 ^@ http://purl.uniprot.org/uniprot/E1QXT2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/633147:OLSU_RS03635 ^@ http://purl.uniprot.org/uniprot/E1QZN5 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/633147:OLSU_RS01830 ^@ http://purl.uniprot.org/uniprot/E1QYM8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS09000 ^@ http://purl.uniprot.org/uniprot/E1QYI6 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/633147:OLSU_RS00530 ^@ http://purl.uniprot.org/uniprot/E1QXW9 ^@ Similarity ^@ In the C-terminal section; belongs to the DHPS family. http://togogenome.org/gene/633147:OLSU_RS02095 ^@ http://purl.uniprot.org/uniprot/E1QYT1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS02600 ^@ http://purl.uniprot.org/uniprot/E1QZ27 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/633147:OLSU_RS08310 ^@ http://purl.uniprot.org/uniprot/E1QXA5 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/633147:OLSU_RS06500 ^@ http://purl.uniprot.org/uniprot/E1QWA0 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/633147:OLSU_RS01150 ^@ http://purl.uniprot.org/uniprot/E1QY90 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/633147:OLSU_RS00835 ^@ http://purl.uniprot.org/uniprot/E1QY28 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/633147:OLSU_RS07750 ^@ http://purl.uniprot.org/uniprot/E1QWZ8 ^@ Similarity|||Subunit ^@ Belongs to the UPF0210 family.|||Homodimer. http://togogenome.org/gene/633147:OLSU_RS05810 ^@ http://purl.uniprot.org/uniprot/E1QVW5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/633147:OLSU_RS00695 ^@ http://purl.uniprot.org/uniprot/E1QY03 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/633147:OLSU_RS01945 ^@ http://purl.uniprot.org/uniprot/E1QYQ2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/633147:OLSU_RS04870 ^@ http://purl.uniprot.org/uniprot/E1R0B9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/633147:OLSU_RS04225 ^@ http://purl.uniprot.org/uniprot/E1QZZ6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/633147:OLSU_RS05505 ^@ http://purl.uniprot.org/uniprot/E1QVQ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS08935 ^@ http://purl.uniprot.org/uniprot/E1QXL3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/633147:OLSU_RS07045 ^@ http://purl.uniprot.org/uniprot/E1QWK9 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/633147:OLSU_RS08545 ^@ http://purl.uniprot.org/uniprot/E1QXE3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/633147:OLSU_RS06595 ^@ http://purl.uniprot.org/uniprot/E1QWB8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/633147:OLSU_RS04060 ^@ http://purl.uniprot.org/uniprot/E1QZW3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/633147:OLSU_RS05620 ^@ http://purl.uniprot.org/uniprot/E1QVS6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homodimer.|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport. http://togogenome.org/gene/633147:OLSU_RS00180 ^@ http://purl.uniprot.org/uniprot/E1QXQ0 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/633147:OLSU_RS08785 ^@ http://purl.uniprot.org/uniprot/E1QXI6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/633147:OLSU_RS00150 ^@ http://purl.uniprot.org/uniprot/E1QXP4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/633147:OLSU_RS04975 ^@ http://purl.uniprot.org/uniprot/E1QVF1 ^@ Function|||Similarity ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. http://togogenome.org/gene/633147:OLSU_RS03475 ^@ http://purl.uniprot.org/uniprot/E1QZK4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/633147:OLSU_RS06785 ^@ http://purl.uniprot.org/uniprot/E1QWF6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/633147:OLSU_RS04500 ^@ http://purl.uniprot.org/uniprot/E1R049 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/633147:OLSU_RS03920 ^@ http://purl.uniprot.org/uniprot/E1QZT4 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.