http://togogenome.org/gene/510516:AO090701000065 ^@ http://purl.uniprot.org/uniprot/Q2U9E1 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/510516:AO090012001013 ^@ http://purl.uniprot.org/uniprot/Q2UBG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxin-16 family.|||Peroxisome membrane http://togogenome.org/gene/510516:AO090003000518 ^@ http://purl.uniprot.org/uniprot/Q2UL78 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090001000666 ^@ http://purl.uniprot.org/uniprot/Q2UMQ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP53 family.|||May play a role in ribosome biogenesis.|||nucleolus|||nucleoplasm http://togogenome.org/gene/510516:AO090120000306 ^@ http://purl.uniprot.org/uniprot/Q2U6B5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL11 family. http://togogenome.org/gene/510516:AO090012000612 ^@ http://purl.uniprot.org/uniprot/Q2UCF5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090010000592 ^@ http://purl.uniprot.org/uniprot/Q2TWE6 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/510516:AO090005001301 ^@ http://purl.uniprot.org/uniprot/Q2UQC9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 9 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/510516:AO090001000593 ^@ http://purl.uniprot.org/uniprot/Q2UMW6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATG12 family.|||Forms a conjugate with atg5.|||Preautophagosomal structure membrane|||Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. Conjugation with atg5 through a ubiquitin-like conjugating system involving also atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function. The atg12-atg5 conjugate functions as an E3-like enzyme which is required for lipidation of atg8 and atg8 association to the vesicle membranes (By similarity). http://togogenome.org/gene/510516:AO090003001520 ^@ http://purl.uniprot.org/uniprot/Q2UIQ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003000468 ^@ http://purl.uniprot.org/uniprot/Q2ULC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.|||Membrane http://togogenome.org/gene/510516:AO090010000040 ^@ http://purl.uniprot.org/uniprot/Q2TXR4 ^@ Similarity ^@ Belongs to the dermatan-sulfate isomerase family. http://togogenome.org/gene/510516:AO090701000359 ^@ http://purl.uniprot.org/uniprot/Q2U8N4 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/510516:AO090120000397 ^@ http://purl.uniprot.org/uniprot/Q2U636 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP core protein family.|||Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.|||Component of the heptameric LSM1-LSM7 complex, which consists of LSM1, LSM2, LSM3, LSM4, LSM5, LSM6 and LSM7. Component of the heptameric LSM2-LSM8 complex, which consists of LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8. The LSm subunits form a seven-membered ring structure with a doughnut shape.|||Nucleus|||cytosol http://togogenome.org/gene/510516:AO090005000449 ^@ http://purl.uniprot.org/uniprot/Q2USF2 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/510516:AO090005000111 ^@ http://purl.uniprot.org/uniprot/Q2UT90 ^@ Similarity ^@ Belongs to the pex2/pex10/pex12 family. http://togogenome.org/gene/510516:AO090102000365 ^@ http://purl.uniprot.org/uniprot/Q2UAJ1 ^@ Similarity ^@ Belongs to the VPS54 family. http://togogenome.org/gene/510516:AO090102000512 ^@ http://purl.uniprot.org/uniprot/Q2UA75 ^@ Similarity ^@ Belongs to the WD repeat PWP2 family. http://togogenome.org/gene/510516:AO090023000001 ^@ http://purl.uniprot.org/uniprot/Q2UIM2 ^@ Domain|||Function|||Induction|||Similarity|||Subcellular Location Annotation ^@ Alpha-L-arabinofuranosidase involved in the degradation of arabinoxylan, a major component of plant hemicellulose. Able to hydrolyze 1,5-, 1,3- and 1,2-alpha-linkages not only in L-arabinofuranosyl oligosaccharides, but also in polysaccharides containing terminal non-reducing L-arabinofuranoses in side chains, like L-arabinan, arabinogalactan and arabinoxylan.|||Belongs to the glycosyl hydrolase 54 family.|||Organized into two domains: an N-terminal catalytic domain and a C-terminal arabinose-binding domain (ABD).|||Repressed by glucose.|||Secreted http://togogenome.org/gene/510516:AO090023000508 ^@ http://purl.uniprot.org/uniprot/Q2UHB9 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/510516:AO090011000831 ^@ http://purl.uniprot.org/uniprot/Q2TZJ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090120000412 ^@ http://purl.uniprot.org/uniprot/Q2U622 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL4 family. http://togogenome.org/gene/510516:AO090103000081 ^@ http://purl.uniprot.org/uniprot/Q2TYW7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090166000084 ^@ http://purl.uniprot.org/uniprot/Q2U9N2 ^@ Cofactor|||Subcellular Location Annotation ^@ Binds 1 Ca(2+) ion per subunit.|||extracellular space http://togogenome.org/gene/510516:AO090001000558 ^@ http://purl.uniprot.org/uniprot/Q2UMZ8 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. http://togogenome.org/gene/510516:AO090120000043 ^@ http://purl.uniprot.org/uniprot/Q2U6Y5 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/510516:AO090701000841 ^@ http://purl.uniprot.org/uniprot/Q2U7H1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/510516:AO090011000745 ^@ http://purl.uniprot.org/uniprot/Q75P26 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetylxylan esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Degrades acetylated xylans by cleaving acetyl side groups from the hetero-xylan backbone. Displays the greatest hydrolytic activity toward alpha-naphthylacetate (C2), lower activity toward alpha-naphthylpropionate (C3) and no detectable activity toward acyl-chain substrates containing four or more carbon atoms.|||Belongs to the carbohydrate esterase 1 (CE1) family. AxeA subfamily.|||Monomer.|||Secreted|||The C-terminal carbohydrate-binding module (CBM) extension found in soem acetylxylan esterases from other species is absent. http://togogenome.org/gene/510516:AO090038000573 ^@ http://purl.uniprot.org/uniprot/Q2U275 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the nucleoporin Nup85 family.|||Component of the nuclear pore complex (NPC).|||Functions as a component of the nuclear pore complex (NPC).|||nuclear pore complex http://togogenome.org/gene/510516:AO090003000402 ^@ http://purl.uniprot.org/uniprot/Q2ULI1 ^@ Activity Regulation|||Similarity ^@ Activated by threonine and tyrosine phosphorylation.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/510516:AO090120000093 ^@ http://purl.uniprot.org/uniprot/Q2U6U4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000888 ^@ http://purl.uniprot.org/uniprot/Q2URC0 ^@ Subcellular Location Annotation ^@ Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090103000013 ^@ http://purl.uniprot.org/uniprot/Q2TZ22 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090012000399 ^@ http://purl.uniprot.org/uniprot/Q2UCY3 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/510516:AO090038000287 ^@ http://purl.uniprot.org/uniprot/Q2U2W9 ^@ Similarity ^@ Belongs to the EF-1-beta/EF-1-delta family. http://togogenome.org/gene/510516:AO090012000036 ^@ http://purl.uniprot.org/uniprot/Q2UDT5 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/510516:AO090003001047 ^@ http://purl.uniprot.org/uniprot/Q2UJW4 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/510516:AO090020000093 ^@ http://purl.uniprot.org/uniprot/Q2U534 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/510516:AO090038000218 ^@ http://purl.uniprot.org/uniprot/Q2U329 ^@ Similarity ^@ Belongs to the HMG-CoA reductase family. http://togogenome.org/gene/510516:AO090003000030 ^@ http://purl.uniprot.org/uniprot/Q2UME6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic PMM family.|||Cytoplasm|||Homodimer.|||Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. http://togogenome.org/gene/510516:AO090012000001 ^@ http://purl.uniprot.org/uniprot/Q2UDW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090026000490 ^@ http://purl.uniprot.org/uniprot/Q2UET5 ^@ Cofactor|||Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.|||Binds 1 Fe cation per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/510516:AO090102000220 ^@ http://purl.uniprot.org/uniprot/Q2UAV4 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. NTM1 family. http://togogenome.org/gene/510516:AO090020000406 ^@ http://purl.uniprot.org/uniprot/Q2U4B9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFS-II family.|||Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.|||Nucleus http://togogenome.org/gene/510516:AO090701000799 ^@ http://purl.uniprot.org/uniprot/Q2U7K8 ^@ Subcellular Location Annotation ^@ Peroxisome membrane http://togogenome.org/gene/510516:AO090124000021 ^@ http://purl.uniprot.org/uniprot/Q2U792 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090026000577 ^@ http://purl.uniprot.org/uniprot/Q2UEK9 ^@ Disruption Phenotype|||Function|||Induction|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Does not affect the production of astellolides.|||Expression is regulated by the secondary metabolite regulator cclA.|||MFS-type transporter; part of the gene cluster that mediates the biosynthesis of astellolides, drimane-type sesquiterpene esters that show antimicrobial, anti-inflammatory, and anti-tumor activities (PubMed:27628599). Seems not to be involved in astellolides translocation (PubMed:27628599).|||Membrane http://togogenome.org/gene/510516:AO090003001402 ^@ http://purl.uniprot.org/uniprot/Q2UJ08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/510516:AO090009000596 ^@ http://purl.uniprot.org/uniprot/Q2UTT8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/510516:AO090023000725 ^@ http://purl.uniprot.org/uniprot/Q2UGS9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ubiA prenyltransferase family.|||Converts protoheme IX and farnesyl diphosphate to heme O.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/510516:AO090102000207 ^@ http://purl.uniprot.org/uniprot/Q2UAW4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S54 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/510516:AO090003000290 ^@ http://purl.uniprot.org/uniprot/Q2ULS2 ^@ Function ^@ The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/510516:AO090011000636 ^@ http://purl.uniprot.org/uniprot/Q2U010 ^@ Similarity ^@ Belongs to the helicase family. SKI2 subfamily. http://togogenome.org/gene/510516:AO090701000884 ^@ http://purl.uniprot.org/uniprot/Q2U7D3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the faeC family.|||Involved in degradation of plant cell walls. Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans, and the feruloyl-galactose ester bond in pectin. Active against paranitrophenyl-acetate, methyl ferulate and wheat arabinoxylan.|||Secreted http://togogenome.org/gene/510516:AO090009000384 ^@ http://purl.uniprot.org/uniprot/Q2UUB2 ^@ Cofactor|||Similarity ^@ Belongs to the cysteine dioxygenase family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/510516:AO090120000434 ^@ http://purl.uniprot.org/uniprot/Q2U603 ^@ Similarity ^@ Belongs to the MNN1/MNT family. http://togogenome.org/gene/510516:AO090003000805 ^@ http://purl.uniprot.org/uniprot/Q2UKH6 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL10 family.|||Ribosomal protein P0 is the functional equivalent of E.coli protein L10. http://togogenome.org/gene/510516:AO090012000307 ^@ http://purl.uniprot.org/uniprot/Q2UD59 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090701000730 ^@ http://purl.uniprot.org/uniprot/Q2U7R7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SecY/SEC61-alpha family.|||Membrane http://togogenome.org/gene/510516:AO090005000884 ^@ http://purl.uniprot.org/uniprot/Q2URC4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycogen debranching enzyme family.|||Cytoplasm|||Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation. http://togogenome.org/gene/510516:AO090026000627 ^@ http://purl.uniprot.org/uniprot/Q2UEG5 ^@ Similarity ^@ Belongs to the yippee family. http://togogenome.org/gene/510516:AO090026000616 ^@ http://purl.uniprot.org/uniprot/Q2UEH6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL24 family. http://togogenome.org/gene/510516:AO090005001230 ^@ http://purl.uniprot.org/uniprot/Q2UQI7 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. http://togogenome.org/gene/510516:AO090001000024 ^@ http://purl.uniprot.org/uniprot/Q2UPC7 ^@ Cofactor|||Disruption Phenotype|||Function|||Similarity ^@ Abolishes completely the formation of aspirochlorine and leads to the accumulation of dechloroaspirochlorine (PubMed:25302411).|||Belongs to the flavin-dependent halogenase family.|||Binds 1 FAD per subunit.|||Flavin-dependent halogenase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411). The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411). One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411). After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411). In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411). Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411). http://togogenome.org/gene/510516:AO090009000128 ^@ http://purl.uniprot.org/uniprot/Q2UUY1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090011000843 ^@ http://purl.uniprot.org/uniprot/Q2TZI2 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/510516:AO090009000607 ^@ http://purl.uniprot.org/uniprot/Q2UTS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VPS18 family.|||Membrane http://togogenome.org/gene/510516:AO090102000121 ^@ http://purl.uniprot.org/uniprot/Q2UB40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL46 family.|||Mitochondrion http://togogenome.org/gene/510516:AO090023000072 ^@ http://purl.uniprot.org/uniprot/Q2UIF7 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090120000359 ^@ http://purl.uniprot.org/uniprot/Q2U668 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LU7TM family.|||Membrane http://togogenome.org/gene/510516:AO090001000733 ^@ http://purl.uniprot.org/uniprot/Q00248 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protein disulfide isomerase family.|||Endoplasmic reticulum lumen|||Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer. http://togogenome.org/gene/510516:AO090206000073 ^@ http://purl.uniprot.org/uniprot/Q2PIT3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M28 family. M28E subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.|||Monomer.|||Secreted http://togogenome.org/gene/510516:AO090701000057 ^@ http://purl.uniprot.org/uniprot/Q2U9E8 ^@ Similarity ^@ In the C-terminal section; belongs to the anthranilate synthase component I family. http://togogenome.org/gene/510516:AO090001000384 ^@ http://purl.uniprot.org/uniprot/Q2UNF8 ^@ Similarity ^@ Belongs to the paxB family. http://togogenome.org/gene/510516:AO090023000503 ^@ http://purl.uniprot.org/uniprot/Q2UHC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the replication factor A protein 2 family.|||Nucleus http://togogenome.org/gene/510516:AO090005000838 ^@ http://purl.uniprot.org/uniprot/Q2URG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.|||Membrane http://togogenome.org/gene/510516:AO090005000284 ^@ http://purl.uniprot.org/uniprot/Q2USV0 ^@ Cofactor|||Similarity ^@ Belongs to the sirtuin family. Class I subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/510516:AO090003000095 ^@ http://purl.uniprot.org/uniprot/Q2UM89 ^@ Subunit ^@ The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. http://togogenome.org/gene/510516:AO090020000659 ^@ http://purl.uniprot.org/uniprot/Q2U3Q8 ^@ Cofactor|||Similarity ^@ Belongs to the cysteine dioxygenase family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/510516:AO090120000486 ^@ http://purl.uniprot.org/uniprot/Q2U5W2 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/510516:AO090003000864 ^@ http://purl.uniprot.org/uniprot/Q2UKC6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090010000476 ^@ http://purl.uniprot.org/uniprot/Q2TWP5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHE9 family.|||Homooligomer.|||Mitochondrion inner membrane|||Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed (By similarity). http://togogenome.org/gene/510516:AO090003001010 ^@ http://purl.uniprot.org/uniprot/Q2UJZ7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL10 family. http://togogenome.org/gene/510516:AO090020000615 ^@ http://purl.uniprot.org/uniprot/Q2U3U4 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/510516:AO090005000412 ^@ http://purl.uniprot.org/uniprot/Q2USI6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ETF alpha-subunit/FixB family.|||Binds 1 FAD per dimer.|||Heterodimer of an alpha and a beta subunit.|||Mitochondrion matrix|||The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/510516:AO090003001209 ^@ http://purl.uniprot.org/uniprot/Q12558 ^@ Function|||Induction|||Similarity ^@ Belongs to the glycosyl hydrolase 31 family.|||By maltose.|||Hydrolyzes malto-oligosaccharides, but has a low activity toward soluble starch. http://togogenome.org/gene/510516:AO090102000400 ^@ http://purl.uniprot.org/uniprot/Q2UAG4 ^@ Similarity ^@ Belongs to the eukaryotic-type N-acetylglucosamine kinase family. http://togogenome.org/gene/510516:AO090005001017 ^@ http://purl.uniprot.org/uniprot/Q2UR13 ^@ Similarity ^@ Belongs to the glycosyltransferase 32 family. http://togogenome.org/gene/510516:AO090102000413 ^@ http://purl.uniprot.org/uniprot/Q2UAF3 ^@ Similarity ^@ Belongs to the MSOX/MTOX family. http://togogenome.org/gene/510516:AO090102000344 ^@ http://purl.uniprot.org/uniprot/Q2UAL0 ^@ Similarity ^@ Belongs to the chloroperoxidase family. http://togogenome.org/gene/510516:AO090010000222 ^@ http://purl.uniprot.org/uniprot/Q2TXA4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090012000443 ^@ http://purl.uniprot.org/uniprot/Q2UCU5 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/510516:AO090023000521 ^@ http://purl.uniprot.org/uniprot/Q2UHA6 ^@ Similarity ^@ Belongs to the DDB1 family. http://togogenome.org/gene/510516:AO090005001538 ^@ http://purl.uniprot.org/uniprot/Q2UPR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.|||Membrane http://togogenome.org/gene/510516:AO090012000727 ^@ http://purl.uniprot.org/uniprot/Q2UC60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCM family.|||Nucleus http://togogenome.org/gene/510516:AO090120000339 ^@ http://purl.uniprot.org/uniprot/Q2U686 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. http://togogenome.org/gene/510516:AO090701000633 ^@ http://purl.uniprot.org/uniprot/Q2U7Z5 ^@ Similarity ^@ Belongs to the CoA-transferase III family. http://togogenome.org/gene/510516:AO090011000757 ^@ http://purl.uniprot.org/uniprot/Q2TZQ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family.|||Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. Acts on lutean, pustulan and 1,6-oligo-beta-D-glucosides (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090003000005 ^@ http://purl.uniprot.org/uniprot/Q2UMH0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. http://togogenome.org/gene/510516:AO090026000294 ^@ http://purl.uniprot.org/uniprot/Q2UF96 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FIS1 family.|||Has a role in mitochondrial fission. Has a role in outer membrane fission but not matrix separation (By similarity).|||Mitochondrion outer membrane|||The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission. http://togogenome.org/gene/510516:AO090005000825 ^@ http://purl.uniprot.org/uniprot/Q2URH6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ARPC2 family.|||Component of the Arp2/3 complex.|||Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.|||cytoskeleton http://togogenome.org/gene/510516:AO090012000802 ^@ http://purl.uniprot.org/uniprot/Q2UBZ8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS15 family. http://togogenome.org/gene/510516:AO090701000427 ^@ http://purl.uniprot.org/uniprot/Q2U8H7 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/510516:AO090009000513 ^@ http://purl.uniprot.org/uniprot/Q2UU07 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/510516:AO090023000962 ^@ http://purl.uniprot.org/uniprot/Q2UG64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sphingosine N-acyltransferase family.|||Membrane http://togogenome.org/gene/510516:AO090023000190 ^@ http://purl.uniprot.org/uniprot/Q2UI52 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/510516:AO090701000813 ^@ http://purl.uniprot.org/uniprot/Q2U7J6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090038000485 ^@ http://purl.uniprot.org/uniprot/Q2U2E6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090010000439 ^@ http://purl.uniprot.org/uniprot/Q2TWS7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Component of the MCM2-7 complex.|||Nucleus http://togogenome.org/gene/510516:AO090124000075 ^@ http://purl.uniprot.org/uniprot/Q2U742 ^@ Similarity ^@ Belongs to the bystin family. http://togogenome.org/gene/510516:AO090124000051 ^@ http://purl.uniprot.org/uniprot/Q2U765 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.|||Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.|||Membrane|||Vacuole membrane http://togogenome.org/gene/510516:AO090038000435 ^@ http://purl.uniprot.org/uniprot/Q2U2J1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit H family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/510516:AO090005000026 ^@ http://purl.uniprot.org/uniprot/Q2UTG5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ZIP transporter (TC 2.A.5) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/510516:AO090120000381 ^@ http://purl.uniprot.org/uniprot/Q2U649 ^@ Function|||Similarity ^@ Belongs to the PIGL family.|||Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol. http://togogenome.org/gene/510516:AO090009000008 ^@ http://purl.uniprot.org/uniprot/Q2UV81 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090012000533 ^@ http://purl.uniprot.org/uniprot/Q2UCM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prohibitin family.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090102000295 ^@ http://purl.uniprot.org/uniprot/Q2UAP8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Tim17/Tim22/Tim23 family.|||Component of the TIM22 complex, whose core is composed of TIM22 and TIM54, associated with the 70 kDa heterohexamer composed of TIM9 and TIM10 (or TIM8 and TIM13).|||Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090005000078 ^@ http://purl.uniprot.org/uniprot/Q2UTC1 ^@ Cofactor ^@ Binds 2 manganese ions per subunit. http://togogenome.org/gene/510516:AO090011000340 ^@ http://purl.uniprot.org/uniprot/Q2U0Q9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit C family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/510516:AO090001000667 ^@ http://purl.uniprot.org/uniprot/Q2UMQ2 ^@ Function|||Similarity ^@ Belongs to the REXO4 family.|||Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs. http://togogenome.org/gene/510516:AO090012000626 ^@ http://purl.uniprot.org/uniprot/Q2UCE3 ^@ Similarity ^@ Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. http://togogenome.org/gene/510516:AO090701000833 ^@ http://purl.uniprot.org/uniprot/Q2U7H8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090138000047 ^@ http://purl.uniprot.org/uniprot/Q2U1Y5 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/510516:AO090011000349 ^@ http://purl.uniprot.org/uniprot/Q2U0Q1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 4 family.|||Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Degrades the rhamnogalacturonan I (RG-I) backbone of pectin (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090011000027 ^@ http://purl.uniprot.org/uniprot/Q2U1H5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 75 family.|||Chitosanase catalyzing the endo-type cleavage of chitosan, the deacylated form of chitin. Chitosanase may be crucial in the degradation of the deacetylated portion of chitin in the fungal cell wall. Chitoolisaccharides produced by the hydrolysis of partially N-acetylated chitosan are known to have many biological activities, including antibacterial activity, immune-enhancing effects, and elicitor activity (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090038000592 ^@ http://purl.uniprot.org/uniprot/Q2U258 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS24 family. http://togogenome.org/gene/510516:AO090038000392 ^@ http://purl.uniprot.org/uniprot/Q2U2M8 ^@ Function|||Subunit ^@ Inclusion body (IB) resident protein that interacts strongly with lipid droplet (LD) proteins. Involved in LD-mediated IB clearing after protein folding stress, probably by enabling access to the IBs of an LD-stored soluble sterol derivative that acts as chaperone in inclusion clearing.|||Interacts with lipid droplet proteins. http://togogenome.org/gene/510516:AO090005001229 ^@ http://purl.uniprot.org/uniprot/Q2UQI8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090003001442 ^@ http://purl.uniprot.org/uniprot/Q2UIX1 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/510516:AO090023000500 ^@ http://purl.uniprot.org/uniprot/Q2UHC5 ^@ Similarity ^@ Belongs to the IPP isomerase type 1 family. http://togogenome.org/gene/510516:AO090001000582 ^@ http://purl.uniprot.org/uniprot/Q2UMX6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tannase family.|||Involved in degradation of plant cell walls. Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans as well as the feruloyl-galactose and feruloyl-arabinose ester bonds in pectin.|||Secreted http://togogenome.org/gene/510516:AO090138000114 ^@ http://purl.uniprot.org/uniprot/Q2U1S6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/510516:AO090003000725 ^@ http://purl.uniprot.org/uniprot/Q9HGY9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.|||Homodimer. http://togogenome.org/gene/510516:AO090102000607 ^@ http://purl.uniprot.org/uniprot/Q2U9Z3 ^@ Function|||Similarity ^@ Belongs to the LCL2 family.|||Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway. http://togogenome.org/gene/510516:AO090005001553 ^@ http://purl.uniprot.org/uniprot/Q2UPQ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family.|||Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan. Involved in the degradation of complex natural cellulosic substrates (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090023000761 ^@ http://purl.uniprot.org/uniprot/Q2UGP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RTC5 family.|||Cytoplasm|||May be involved in a process influencing telomere capping. http://togogenome.org/gene/510516:AO090010000096 ^@ http://purl.uniprot.org/uniprot/Q2TXL6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 76 family. http://togogenome.org/gene/510516:AO090023000342 ^@ http://purl.uniprot.org/uniprot/Q2UHR5 ^@ PTM ^@ The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/510516:AO090020000410 ^@ http://purl.uniprot.org/uniprot/Q2U4B6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ALG6/ALG8 glucosyltransferase family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/510516:AO090023000856 ^@ http://purl.uniprot.org/uniprot/Q2UGF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily.|||Mitochondrion matrix http://togogenome.org/gene/510516:AO090023000460 ^@ http://purl.uniprot.org/uniprot/Q2UHG1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/510516:AO090001000670 ^@ http://purl.uniprot.org/uniprot/Q2UMP9 ^@ Similarity ^@ Belongs to the peptidase C12 family. http://togogenome.org/gene/510516:AO090003000929 ^@ http://purl.uniprot.org/uniprot/Q2UK70 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/510516:AO090005000945 ^@ http://purl.uniprot.org/uniprot/Q2UR69 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/510516:AO090308000018 ^@ http://purl.uniprot.org/uniprot/Q2UPF3 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/510516:AO090005000730 ^@ http://purl.uniprot.org/uniprot/Q2URQ4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase proteolipid subunit family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.|||Vacuole membrane http://togogenome.org/gene/510516:AO090009000405 ^@ http://purl.uniprot.org/uniprot/Q2UU95 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.|||Mitochondrion inner membrane|||Monomer. http://togogenome.org/gene/510516:AO090001000030 ^@ http://purl.uniprot.org/uniprot/Q2UPC2 ^@ Function|||Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Gamma-glutamyl cyclotransferase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411). The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411). One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411). After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411). In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411). Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411). http://togogenome.org/gene/510516:AO090005000956 ^@ http://purl.uniprot.org/uniprot/Q2UR62 ^@ Similarity ^@ Belongs to the oxoprolinase family. http://togogenome.org/gene/510516:AO090023000346 ^@ http://purl.uniprot.org/uniprot/Q2UHR2 ^@ Function|||Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family.|||Xylitol dehydrogenase which catalyzes the conversion of xylitol to D-xylulose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway. http://togogenome.org/gene/510516:AO090026000203 ^@ http://purl.uniprot.org/uniprot/Q2UFH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SF3B1 family.|||Nucleus http://togogenome.org/gene/510516:AO090009000468 ^@ http://purl.uniprot.org/uniprot/Q2UU43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CCC1 family.|||Membrane http://togogenome.org/gene/510516:AO090026000380 ^@ http://purl.uniprot.org/uniprot/Q2UF23 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/510516:AO090005000086 ^@ http://purl.uniprot.org/uniprot/Q2UTB3 ^@ Similarity ^@ Belongs to the class-I DAHP synthase family. http://togogenome.org/gene/510516:AO090023000188 ^@ http://purl.uniprot.org/uniprot/Q2UI54 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090012000600 ^@ http://purl.uniprot.org/uniprot/Q2UCG4 ^@ Similarity ^@ Belongs to the G-alpha family. G(q) subfamily. http://togogenome.org/gene/510516:AO090005000067 ^@ http://purl.uniprot.org/uniprot/Q2UTD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 28 family.|||Secreted http://togogenome.org/gene/510516:AO090003001207 ^@ http://purl.uniprot.org/uniprot/Q2UJH8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090012000997 ^@ http://purl.uniprot.org/uniprot/Q2UBH5 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATG8 family.|||Lipid droplet|||The C-terminal 2 residues are removed by atg4 to expose Gly-116 at the C-terminus. The c-terminal Gly is then amidated with phosphatidylethanolamine by an activating system similar to that for ubiquitin.|||Ubiquitin-like modifier involved in autophagosomes formation. With atg4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. The atg8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity). Required for both the differentiation of aerial hyphae and conidial germination (PubMed:16896216).|||Vacuole membrane|||autophagosome membrane http://togogenome.org/gene/510516:AO090005000220 ^@ http://purl.uniprot.org/uniprot/Q2UT03 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090009000186 ^@ http://purl.uniprot.org/uniprot/Q2UUT4 ^@ Function|||Similarity ^@ Belongs to the WD repeat DDB2/WDR76 family.|||DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. http://togogenome.org/gene/510516:AO090102000611 ^@ http://purl.uniprot.org/uniprot/Q2U9Y9 ^@ Similarity ^@ Belongs to the terpene cyclase/mutase family. http://togogenome.org/gene/510516:AO090038000194 ^@ http://purl.uniprot.org/uniprot/Q2U346 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090001000124 ^@ http://purl.uniprot.org/uniprot/Q2UP40 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005001514 ^@ http://purl.uniprot.org/uniprot/Q2UPT8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ZIP transporter (TC 2.A.5) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/510516:AO090012000983 ^@ http://purl.uniprot.org/uniprot/Q2UBI6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003000321 ^@ http://purl.uniprot.org/uniprot/Q2ULP9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 15 family. http://togogenome.org/gene/510516:AO090001000486 ^@ http://purl.uniprot.org/uniprot/Q2UN67 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090012000350 ^@ http://purl.uniprot.org/uniprot/Q2UD25 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/510516:AO090001000555 ^@ http://purl.uniprot.org/uniprot/Q2UN01 ^@ Function|||Similarity ^@ Belongs to the BCKDHA family.|||The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/510516:AO090701000061 ^@ http://purl.uniprot.org/uniprot/Q2U9E4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OB-RGRP/VPS55 family.|||Membrane http://togogenome.org/gene/510516:AO090003000751 ^@ http://purl.uniprot.org/uniprot/Q2UKM3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/510516:AO090010000465 ^@ http://purl.uniprot.org/uniprot/Q2TWQ5 ^@ Similarity ^@ Belongs to the glycosyltransferase 15 family. http://togogenome.org/gene/510516:AO090102000339 ^@ http://purl.uniprot.org/uniprot/Q2UAL5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Expected to bind 2 Fe(2+) ions per subunit.|||Membrane|||Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. http://togogenome.org/gene/510516:AO090023000859 ^@ http://purl.uniprot.org/uniprot/Q2UGF6 ^@ Similarity ^@ Belongs to the helicase family. SKI2 subfamily. http://togogenome.org/gene/510516:AO090005000107 ^@ http://purl.uniprot.org/uniprot/Q2UT94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRP17 family.|||nucleolus http://togogenome.org/gene/510516:AO090102000373 ^@ http://purl.uniprot.org/uniprot/Q2UAI3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CWC16 family. YJU2 subfamily.|||Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.|||Nucleus|||Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. http://togogenome.org/gene/510516:AO090020000055 ^@ http://purl.uniprot.org/uniprot/Q2U564 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/510516:AO090701000728 ^@ http://purl.uniprot.org/uniprot/Q2U7R9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ORC2 family.|||Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.|||Component of the origin recognition complex (ORC).|||Nucleus http://togogenome.org/gene/510516:AO090120000456 ^@ http://purl.uniprot.org/uniprot/Q2U5Y5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.|||Membrane http://togogenome.org/gene/510516:AO090038000576 ^@ http://purl.uniprot.org/uniprot/Q2U272 ^@ Similarity ^@ Belongs to the ADIP family. http://togogenome.org/gene/510516:AO090026000019 ^@ http://purl.uniprot.org/uniprot/Q2UFZ6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090023000702 ^@ http://purl.uniprot.org/uniprot/Q2UGV0 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family. Prx6 subfamily.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/510516:AO090103000165 ^@ http://purl.uniprot.org/uniprot/Q2TYP5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090026000002 ^@ http://purl.uniprot.org/uniprot/Q2UG12 ^@ Similarity ^@ Belongs to the tryptophan dimethylallyltransferase family. http://togogenome.org/gene/510516:AO090120000309 ^@ http://purl.uniprot.org/uniprot/Q2U6B3 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/510516:AO090003000834 ^@ http://purl.uniprot.org/uniprot/Q2UKF0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the VTS1 family.|||Monomer. Binds to RNA.|||P-body|||cytosol http://togogenome.org/gene/510516:AO090011000346 ^@ http://purl.uniprot.org/uniprot/Q2U0Q3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090005000672 ^@ http://purl.uniprot.org/uniprot/Q2URV8 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/510516:AO090120000307 ^@ http://purl.uniprot.org/uniprot/Q2U6B4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SVF1 family.|||Cytoplasm http://togogenome.org/gene/510516:AO090020000344 ^@ http://purl.uniprot.org/uniprot/Q2U4H2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Mitochondrion http://togogenome.org/gene/510516:AO090026000028 ^@ http://purl.uniprot.org/uniprot/Q2UFY7 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/510516:AO090003000688 ^@ http://purl.uniprot.org/uniprot/Q2UKT0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.|||Belongs to the arsA ATPase family.|||Cytoplasm|||Endoplasmic reticulum|||Homodimer. http://togogenome.org/gene/510516:AO090009000650 ^@ http://purl.uniprot.org/uniprot/Q2UTP3 ^@ Similarity ^@ Belongs to the SWI5/SAE3 family. http://togogenome.org/gene/510516:AO090011000261 ^@ http://purl.uniprot.org/uniprot/Q2U0X7 ^@ Similarity ^@ Belongs to the CoA-transferase III family. http://togogenome.org/gene/510516:AO090020000083 ^@ http://purl.uniprot.org/uniprot/Q2U542 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DASH complex SPC34 family.|||Nucleus|||kinetochore|||spindle http://togogenome.org/gene/510516:AO090010000674 ^@ http://purl.uniprot.org/uniprot/Q2TW75 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090120000063 ^@ http://purl.uniprot.org/uniprot/Q2U6W9 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090012000103 ^@ http://purl.uniprot.org/uniprot/Q2UDN5 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/510516:AO090001000045 ^@ http://purl.uniprot.org/uniprot/Q2UPA7 ^@ Function|||Similarity ^@ Belongs to the Gfo/Idh/MocA family.|||Dehydrogenase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411). The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411). One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411). After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411). In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411). Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411). http://togogenome.org/gene/510516:AO090001000707 ^@ http://purl.uniprot.org/uniprot/Q2UML8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/510516:AO090102000543 ^@ http://purl.uniprot.org/uniprot/Q2UA50 ^@ Similarity ^@ Belongs to the FMO family. http://togogenome.org/gene/510516:AO090102000142 ^@ http://purl.uniprot.org/uniprot/Q2UB23 ^@ Similarity ^@ Belongs to the peptidase M24 family. http://togogenome.org/gene/510516:AO090102000375 ^@ http://purl.uniprot.org/uniprot/Q2UAI1 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/510516:AO090009000325 ^@ http://purl.uniprot.org/uniprot/Q2UUG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the rad1 family.|||Nucleus http://togogenome.org/gene/510516:AO090701000860 ^@ http://purl.uniprot.org/uniprot/Q2U7F5 ^@ Similarity ^@ Belongs to the peptidase M28 family. http://togogenome.org/gene/510516:AO090138000104 ^@ http://purl.uniprot.org/uniprot/Q2U1T5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090701000168 ^@ http://purl.uniprot.org/uniprot/Q2U954 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase d subunit family.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090003001508 ^@ http://purl.uniprot.org/uniprot/Q2UIR6 ^@ Similarity ^@ Belongs to the hexokinase family. http://togogenome.org/gene/510516:AO090701000149 ^@ http://purl.uniprot.org/uniprot/Q2U968 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC16 family.|||Endoplasmic reticulum membrane|||Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy (By similarity). http://togogenome.org/gene/510516:AO090206000115 ^@ http://purl.uniprot.org/uniprot/Q2PIQ0 ^@ Similarity ^@ Belongs to the AFG1 ATPase family. http://togogenome.org/gene/510516:AO090023000309 ^@ http://purl.uniprot.org/uniprot/Q2UHU3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 7 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/510516:AO090003000261 ^@ http://purl.uniprot.org/uniprot/Q2ULU8 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/510516:AO090701000058 ^@ http://purl.uniprot.org/uniprot/Q2U9E7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 6 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/510516:AO090011000308 ^@ http://purl.uniprot.org/uniprot/Q2U0T9 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/510516:AO090003000042 ^@ http://purl.uniprot.org/uniprot/Q2UMD5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 35 family.|||Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.|||Secreted http://togogenome.org/gene/510516:AO090012000033 ^@ http://purl.uniprot.org/uniprot/Q2UDT8 ^@ Similarity ^@ Belongs to the class-A beta-lactamase family. http://togogenome.org/gene/510516:AO090005001624 ^@ http://purl.uniprot.org/uniprot/Q2UPI8 ^@ Similarity ^@ Belongs to the WD repeat rae1 family. http://togogenome.org/gene/510516:AO090701000321 ^@ http://purl.uniprot.org/uniprot/Q2U8R6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 1 family.|||Binds 1 Ca(2+) ion per subunit.|||Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090102000358 ^@ http://purl.uniprot.org/uniprot/Q2UAJ6 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/510516:AO090020000270 ^@ http://purl.uniprot.org/uniprot/Q2U4N3 ^@ Similarity ^@ Belongs to the FAH family. http://togogenome.org/gene/510516:AO090005000767 ^@ http://purl.uniprot.org/uniprot/Q2URM5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/510516:AO090120000281 ^@ http://purl.uniprot.org/uniprot/Q2U6D8 ^@ Function|||Subcellular Location Annotation ^@ Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).|||Membrane|||Mitochondrion inner membrane|||Nucleus http://togogenome.org/gene/510516:AO090020000504 ^@ http://purl.uniprot.org/uniprot/Q2U440 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/510516:AO090102000389 ^@ http://purl.uniprot.org/uniprot/Q2UAH0 ^@ Similarity ^@ In the N-terminal section; belongs to the FGAMS family. http://togogenome.org/gene/510516:AO090023000709 ^@ http://purl.uniprot.org/uniprot/Q2UGU4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the fungal TPase family.|||First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.|||Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.|||Nucleus http://togogenome.org/gene/510516:AO090003001300 ^@ http://purl.uniprot.org/uniprot/Q2UJA2 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/510516:AO090009000291 ^@ http://purl.uniprot.org/uniprot/Q2UUJ5 ^@ Similarity ^@ Belongs to the peptidase S8 family. Furin subfamily. http://togogenome.org/gene/510516:AO090103000225 ^@ http://purl.uniprot.org/uniprot/Q2TYI9 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/510516:AO090026000634 ^@ http://purl.uniprot.org/uniprot/Q2UEF9 ^@ Similarity ^@ Belongs to the gamma-glutamylcyclotransferase family. http://togogenome.org/gene/510516:AO090009000488 ^@ http://purl.uniprot.org/uniprot/Q2UU23 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M28 family.|||Binds 2 Zn(2+) ions per subunit.|||May be involved in vacuolar sorting and osmoregulation.|||Vacuole membrane http://togogenome.org/gene/510516:AO090012000452 ^@ http://purl.uniprot.org/uniprot/Q2UCT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAM41 family.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090003000765 ^@ http://purl.uniprot.org/uniprot/Q2UKK9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090001000748 ^@ http://purl.uniprot.org/uniprot/Q2UMH9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RFT1 family.|||Endoplasmic reticulum membrane|||May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane.|||Membrane http://togogenome.org/gene/510516:AO090003000090 ^@ http://purl.uniprot.org/uniprot/Q9UUZ9 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the THI4 family.|||Binds 1 Fe cation per subunit.|||Cytoplasm|||During the catalytic reaction, a sulfide is transferred from Cys-216 to a reaction intermediate, generating a dehydroalanine residue.|||Homooctamer.|||Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.|||Nucleus http://togogenome.org/gene/510516:AO090001000257 ^@ http://purl.uniprot.org/uniprot/Q2UNR9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090012000865 ^@ http://purl.uniprot.org/uniprot/Q2UBU1 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/510516:AO090001000709 ^@ http://purl.uniprot.org/uniprot/Q2UML6 ^@ Cofactor|||Similarity ^@ Belongs to the sirtuin family. Class I subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/510516:AO090001000627 ^@ http://purl.uniprot.org/uniprot/Q2UMT9 ^@ Domain|||Function|||Induction|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. YAP subfamily.|||Contains two cysteine rich domains (CRD), referred to as the N- and C-terminal CRD's, n-CRD and c-CRD, respectively. A nuclear export signal is embedded in the c-CRD, with which the nuclear export proteins interact only in the absence of disulfide bonds (or otherwise oxidized cysteines) within the c-CRD or between the c-CRD and the n-CRD.|||Cytoplasm|||Depending on the oxidative stress inducing agent, yap1 can undergo two distinct conformational changes, both involving disulfide bond formation, and both masking the nuclear export signal, thus abolishing nuclear export.|||Expression is enhanced upon oxidative stress stimuli.|||Nucleus|||Transcription activator involved in oxidative stress response and redox homeostasis (PubMed:31366149). Regulates the transcription of genes encoding antioxidant enzymes and components of the cellular thiol-reducing pathways (By similarity). http://togogenome.org/gene/510516:AO090120000001 ^@ http://purl.uniprot.org/uniprot/Q2U724 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. http://togogenome.org/gene/510516:AO090003001290 ^@ http://purl.uniprot.org/uniprot/Q2UJB2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090023000410 ^@ http://purl.uniprot.org/uniprot/Q2UHK6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000202 ^@ http://purl.uniprot.org/uniprot/Q2UT17 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/510516:AO090103000359 ^@ http://purl.uniprot.org/uniprot/Q2TY79 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090003001057 ^@ http://purl.uniprot.org/uniprot/Q2UJV6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GINS3/PSF3 family.|||Component of the GINS complex.|||Nucleus|||The GINS complex plays an essential role in the initiation of DNA replication. http://togogenome.org/gene/510516:AO090005001456 ^@ http://purl.uniprot.org/uniprot/Q2UPY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GPC1 family.|||Membrane http://togogenome.org/gene/510516:AO090701000815 ^@ http://purl.uniprot.org/uniprot/Q2U7J4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090701000220 ^@ http://purl.uniprot.org/uniprot/Q2U908 ^@ Similarity ^@ Belongs to the peptidase S10 family. http://togogenome.org/gene/510516:AO090012000706 ^@ http://purl.uniprot.org/uniprot/Q2UC77 ^@ Similarity ^@ Belongs to the peptidase S10 family. http://togogenome.org/gene/510516:AO090102000157 ^@ http://purl.uniprot.org/uniprot/Q2UB09 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/510516:AO090701000066 ^@ http://purl.uniprot.org/uniprot/Q2U9E0 ^@ Function|||Similarity ^@ Catalyzes the second and fifth step in the 'de novo' purine biosynthesis pathway; contains phosphoribosylamine--glycine ligase (GARS) and phosphoribosylformylglycinamidine cyclo-ligase (AIRS) activities.|||In the C-terminal section; belongs to the AIR synthase family.|||In the N-terminal section; belongs to the GARS family. http://togogenome.org/gene/510516:AO090103000235 ^@ http://purl.uniprot.org/uniprot/Q2TYI1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090701000622 ^@ http://purl.uniprot.org/uniprot/Q2U804 ^@ Similarity ^@ Belongs to the amino acid/polyamine transporter 2 family. http://togogenome.org/gene/510516:AO090020000594 ^@ http://purl.uniprot.org/uniprot/Q2U3W1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GTR/RAG GTP-binding protein family.|||Component of the GSE complex.|||GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions. http://togogenome.org/gene/510516:AO090701000095 ^@ http://purl.uniprot.org/uniprot/Q2U9B7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enhancer of polycomb family.|||Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.|||Nucleus http://togogenome.org/gene/510516:AO090011000712 ^@ http://purl.uniprot.org/uniprot/Q2TZU9 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090003000257 ^@ http://purl.uniprot.org/uniprot/Q2ULV1 ^@ Function|||Similarity ^@ Belongs to the heat shock protein 70 family.|||Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis. http://togogenome.org/gene/510516:AO090011000363 ^@ http://purl.uniprot.org/uniprot/Q2U0N7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090206000105 ^@ http://purl.uniprot.org/uniprot/Q2PIQ9 ^@ Similarity ^@ Belongs to the PHP hydrolase family. HisK subfamily. http://togogenome.org/gene/510516:AO090103000268 ^@ http://purl.uniprot.org/uniprot/Q2TYF7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/510516:AO090011000780 ^@ http://purl.uniprot.org/uniprot/Q2TZP0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/510516:AO090701000511 ^@ http://purl.uniprot.org/uniprot/Q2U8A2 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/510516:AO090020000684 ^@ http://purl.uniprot.org/uniprot/Q2U3N8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090701000119 ^@ http://purl.uniprot.org/uniprot/Q2U997 ^@ Similarity ^@ Belongs to the CWC21 family. http://togogenome.org/gene/510516:AO090020000328 ^@ http://purl.uniprot.org/uniprot/Q2U4I7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CSN2 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/510516:AO090005001412 ^@ http://purl.uniprot.org/uniprot/Q2UQ28 ^@ Similarity ^@ Belongs to the eIF-2-beta/eIF-5 family. http://togogenome.org/gene/510516:AO090003001545 ^@ http://purl.uniprot.org/uniprot/Q2UIN6 ^@ Similarity ^@ Belongs to the NRP synthetase family. http://togogenome.org/gene/510516:AO090026000590 ^@ http://purl.uniprot.org/uniprot/Q2UEJ7 ^@ Similarity ^@ Belongs to the WD repeat RAPTOR family. http://togogenome.org/gene/510516:AO090103000127 ^@ http://purl.uniprot.org/uniprot/Q2TYS6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/510516:AO090001000585 ^@ http://purl.uniprot.org/uniprot/Q2UMX3 ^@ Subcellular Location Annotation|||Subunit ^@ Component of the ESCRT-0 complex composed of HSE1 and VPS27.|||Membrane http://togogenome.org/gene/510516:AO090206000124 ^@ http://purl.uniprot.org/uniprot/Q2PIP2 ^@ Similarity ^@ Belongs to the pyrroline-5-carboxylate reductase family. http://togogenome.org/gene/510516:AO090012000349 ^@ http://purl.uniprot.org/uniprot/Q2UD26 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/510516:AO090102000609 ^@ http://purl.uniprot.org/uniprot/Q2U9Z1 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/510516:AO090009000559 ^@ http://purl.uniprot.org/uniprot/Q2UTX0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090001000708 ^@ http://purl.uniprot.org/uniprot/Q2UML7 ^@ Similarity ^@ Belongs to the COG4 family. http://togogenome.org/gene/510516:AO090102000094 ^@ http://purl.uniprot.org/uniprot/Q2UB63 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090011000538 ^@ http://purl.uniprot.org/uniprot/Q2U091 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090001000468 ^@ http://purl.uniprot.org/uniprot/Q2UN82 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SDS23 family.|||Cytoplasm|||Involved in DNA replication and cell separation. http://togogenome.org/gene/510516:AO090011000488 ^@ http://purl.uniprot.org/uniprot/Q2U0D1 ^@ Function ^@ Delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides. Required for the formation of the di-unsaturated sphingoid base (E,E)-sphinga-4,8-dienine during glucosylceramide (GluCer) biosynthesis. http://togogenome.org/gene/510516:AO090701000334 ^@ http://purl.uniprot.org/uniprot/Q2U8Q6 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/510516:AO090124000035 ^@ http://purl.uniprot.org/uniprot/Q2U779 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090012000883 ^@ http://purl.uniprot.org/uniprot/Q2UBS7 ^@ Similarity ^@ Belongs to the NmrA-type oxidoreductase family. http://togogenome.org/gene/510516:AO090003001233 ^@ http://purl.uniprot.org/uniprot/Q2UJF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/510516:AO090102000401 ^@ http://purl.uniprot.org/uniprot/Q2UAG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-93 family.|||Membrane http://togogenome.org/gene/510516:AO090012000100 ^@ http://purl.uniprot.org/uniprot/Q2UDN8 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/510516:AO090120000207 ^@ http://purl.uniprot.org/uniprot/Q2U6J7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/510516:AO090701000351 ^@ http://purl.uniprot.org/uniprot/Q2U8P0 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/510516:AO090009000289 ^@ http://purl.uniprot.org/uniprot/Q2UUJ7 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/510516:AO090011000456 ^@ http://purl.uniprot.org/uniprot/Q2U0F8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COQ7 family.|||Binds 2 iron ions per subunit.|||Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.|||Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090001000162 ^@ http://purl.uniprot.org/uniprot/Q2UP04 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/510516:AO090005001589 ^@ http://purl.uniprot.org/uniprot/Q2UPM1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090023000754 ^@ http://purl.uniprot.org/uniprot/Q2UGQ6 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/510516:AO090011000458 ^@ http://purl.uniprot.org/uniprot/Q2U0F6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090009000219 ^@ http://purl.uniprot.org/uniprot/Q2UUQ5 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.|||Can also use Mn(2+) ion. http://togogenome.org/gene/510516:AO090010000475 ^@ http://purl.uniprot.org/uniprot/Q2TWP6 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rieske iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster per subunit.|||Membrane|||Mitochondrion inner membrane|||The Rieske protein is a high potential 2Fe-2S protein. http://togogenome.org/gene/510516:AO090011000323 ^@ http://purl.uniprot.org/uniprot/Q2U0S6 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/510516:AO090026000739 ^@ http://purl.uniprot.org/uniprot/Q2UE71 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090003001250 ^@ http://purl.uniprot.org/uniprot/Q2UJE5 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. http://togogenome.org/gene/510516:AO090120000474 ^@ http://purl.uniprot.org/uniprot/Q06902 ^@ Activity Regulation|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A1 family.|||Inhibited by sodium lauryl sulfonate.|||Secreted|||Secreted aspartic endopeptidase that allows assimilation of proteinaceous substrates. The scissile peptide bond is attacked by a nucleophilic water molecule activated by two aspartic residues in the active site. Shows a broad primary substrate specificity. Favors hydrophobic residues at the P1 and P1' positions, but also accepts a lysine residue in the P1 position, leading to the activation of trypsinogen and chymotrypsinogen A. Hydrolyzes bovine chymotrysinogen A between positions 'Arg-15' and 'Ile-16'.|||Two isozymes of this enzyme exist which differ only by their non-covalent association with carbohydrate. http://togogenome.org/gene/510516:AO090103000149 ^@ http://purl.uniprot.org/uniprot/Q2TYQ8 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/510516:AO090026000267 ^@ http://purl.uniprot.org/uniprot/Q2UFB7 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c family.|||Binds 1 heme group per subunit.|||Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.|||Mitochondrion intermembrane space http://togogenome.org/gene/510516:AO090120000283 ^@ http://purl.uniprot.org/uniprot/Q2U6D6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.|||Cytoplasm|||S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86. http://togogenome.org/gene/510516:AO090001000026 ^@ http://purl.uniprot.org/uniprot/Q2UPC5 ^@ Function|||Similarity ^@ Belongs to the cytochrome P450 family.|||Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411). The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411). One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411). After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411). In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411). Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411). http://togogenome.org/gene/510516:AO090003000855 ^@ http://purl.uniprot.org/uniprot/Q2UKD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRM MRD1 family.|||Nucleus http://togogenome.org/gene/510516:AO090026000184 ^@ http://purl.uniprot.org/uniprot/Q2UFJ4 ^@ Domain|||Similarity ^@ A pair of annexin repeats may form one binding site for calcium and phospholipid.|||Belongs to the annexin family. http://togogenome.org/gene/510516:AO090138000121 ^@ http://purl.uniprot.org/uniprot/Q2U1R9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090026000725 ^@ http://purl.uniprot.org/uniprot/Q2UE84 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090003000676 ^@ http://purl.uniprot.org/uniprot/Q2UKU1 ^@ Similarity ^@ Belongs to the RMD1/sif2 family. http://togogenome.org/gene/510516:AO090010000079 ^@ http://purl.uniprot.org/uniprot/Q2TXN1 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/510516:AO090166000050 ^@ http://purl.uniprot.org/uniprot/Q2U9R3 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/510516:AO090012000710 ^@ http://purl.uniprot.org/uniprot/Q2UC75 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090012000385 ^@ http://purl.uniprot.org/uniprot/Q2UCZ4 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090003001337 ^@ http://purl.uniprot.org/uniprot/Q2UJ68 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/510516:AO090020000571 ^@ http://purl.uniprot.org/uniprot/Q2U3Y2 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. http://togogenome.org/gene/510516:AO090120000500 ^@ http://purl.uniprot.org/uniprot/Q2U5V2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat PRP19 family.|||Homotetramer.|||Nucleus|||Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome. http://togogenome.org/gene/510516:AO090103000383 ^@ http://purl.uniprot.org/uniprot/Q2TY57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/510516:AO090020000342 ^@ http://purl.uniprot.org/uniprot/Q2U4H4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat IPI3/WDR18 family.|||Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.|||Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.|||Nucleus http://togogenome.org/gene/510516:AO090020000035 ^@ http://purl.uniprot.org/uniprot/Q2U583 ^@ Similarity ^@ In the C-terminal section; belongs to the trehalose phosphatase family.|||In the N-terminal section; belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/510516:AO090166000070 ^@ http://purl.uniprot.org/uniprot/Q2U9P4 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090011000506 ^@ http://purl.uniprot.org/uniprot/Q2U0B5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS14 family. http://togogenome.org/gene/510516:AO090003000497 ^@ http://purl.uniprot.org/uniprot/Q2UL94 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/510516:AO090026000740 ^@ http://purl.uniprot.org/uniprot/Q2UE70 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/510516:AO090010000644 ^@ http://purl.uniprot.org/uniprot/Q2TWA0 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/510516:AO090038000594 ^@ http://purl.uniprot.org/uniprot/Q2U256 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.|||Nucleus|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). http://togogenome.org/gene/510516:AO090005000807 ^@ http://purl.uniprot.org/uniprot/Q2URJ2 ^@ Similarity ^@ Belongs to the WD repeat TAF5 family. http://togogenome.org/gene/510516:AO090011000790 ^@ http://purl.uniprot.org/uniprot/Q2TZN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prohibitin family.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090003001225 ^@ http://purl.uniprot.org/uniprot/Q2UJG7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycosyl hydrolase 47 family.|||Cytoplasmic vesicle lumen|||Involved in the maturation of Asn-linked oligosaccharides. Progressively trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).|||Monomer. http://togogenome.org/gene/510516:AO090005000860 ^@ http://purl.uniprot.org/uniprot/Q2URE6 ^@ Similarity ^@ Belongs to the FAH family. http://togogenome.org/gene/510516:AO090038000057 ^@ http://purl.uniprot.org/uniprot/Q2U3F8 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/510516:AO090102000135 ^@ http://purl.uniprot.org/uniprot/Q2UB29 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090026000702 ^@ http://purl.uniprot.org/uniprot/Q2UEA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20A family.|||Secreted http://togogenome.org/gene/510516:AO090023001001 ^@ http://purl.uniprot.org/uniprot/Q2UG29 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family.|||Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090010000011 ^@ http://purl.uniprot.org/uniprot/Q2TXU2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090011000933 ^@ http://purl.uniprot.org/uniprot/Q2TZA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP receptor beta subunit family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/510516:AO090020000240 ^@ http://purl.uniprot.org/uniprot/Q2U4Q8 ^@ Similarity ^@ Belongs to the NRP synthetase family. http://togogenome.org/gene/510516:AO090009000502 ^@ http://purl.uniprot.org/uniprot/O13415 ^@ Function|||Subcellular Location Annotation ^@ Major nitrogen regulatory protein. Positively acting regulatory gene of nitrogen metabolite repression.|||Nucleus http://togogenome.org/gene/510516:AO090005000695 ^@ http://purl.uniprot.org/uniprot/Q2URT6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.|||Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate-binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions.|||Heterodimer consisting of MSH2-MSH3 (MutS beta). Forms a ternary complex with MutL alpha (MLH1-PMS1).|||Nucleus http://togogenome.org/gene/510516:AO090003000798 ^@ http://purl.uniprot.org/uniprot/Q2UKI1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/510516:AO090003000424 ^@ http://purl.uniprot.org/uniprot/Q2ULG1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UbiD family. UbiD-like/FDC subfamily.|||Binds 1 prenylated FMN (prenyl-FMN) per subunit.|||Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites.|||Cytoplasm|||Homodimer. May form higher order oligomers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/510516:AO090003001339 ^@ http://purl.uniprot.org/uniprot/Q2UJ66 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRM6/GCD10 family.|||Heterotetramer; composed of two copies of TRM6 and two copies of TRM61.|||Nucleus|||Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. http://togogenome.org/gene/510516:AO090701000197 ^@ http://purl.uniprot.org/uniprot/Q2U927 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/510516:AO090003000554 ^@ http://purl.uniprot.org/uniprot/Q2UL45 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.|||Belongs to the NDC80/HEC1 family.|||Component of the NDC80 complex, which consists of ndc80, nuf2, spc24 and spc25.|||Nucleus|||kinetochore http://togogenome.org/gene/510516:AO090026000414 ^@ http://purl.uniprot.org/uniprot/Q2UEZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.|||Membrane http://togogenome.org/gene/510516:AO090012000813 ^@ http://purl.uniprot.org/uniprot/Q2UBY7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 72 family.|||Cell membrane|||Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in cell wall morphogenesis. http://togogenome.org/gene/510516:AO090020000202 ^@ http://purl.uniprot.org/uniprot/Q2U4U4 ^@ Similarity ^@ Belongs to the PPC synthetase family. http://togogenome.org/gene/510516:AO090003000401 ^@ http://purl.uniprot.org/uniprot/Q2ULI2 ^@ Similarity ^@ Belongs to the uroporphyrinogen-III synthase family. http://togogenome.org/gene/510516:AO090120000326 ^@ http://purl.uniprot.org/uniprot/Q2U697 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.|||Component of the nucleolar and nucleoplasmic pre-60S ribosomal particle.|||Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.|||nucleolus http://togogenome.org/gene/510516:AO090005001627 ^@ http://purl.uniprot.org/uniprot/Q2UPI5 ^@ Similarity ^@ Belongs to the MYG1 family. http://togogenome.org/gene/510516:AO090011000038 ^@ http://purl.uniprot.org/uniprot/Q2U1G5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090038000451 ^@ http://purl.uniprot.org/uniprot/Q2U2H8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.|||Cytoplasm|||Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.|||Monomer. http://togogenome.org/gene/510516:AO090012000934 ^@ http://purl.uniprot.org/uniprot/Q2UBN0 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. METL family.|||S-adenosyl-L-methionine-dependent methyltransferase. http://togogenome.org/gene/510516:AO090003001507 ^@ http://purl.uniprot.org/uniprot/Q2UIR7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cutinase family.|||Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.|||Secreted http://togogenome.org/gene/510516:AO090005000428 ^@ http://purl.uniprot.org/uniprot/Q2USH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.|||Cytoplasm|||Membrane http://togogenome.org/gene/510516:AO090026000449 ^@ http://purl.uniprot.org/uniprot/Q2UEW6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EXO70 family.|||Bud|||Bud neck|||Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst. http://togogenome.org/gene/510516:AO090020000472 ^@ http://purl.uniprot.org/uniprot/Q2U465 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090012000676 ^@ http://purl.uniprot.org/uniprot/Q2UCA3 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family. Prx5 subfamily.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/510516:AO090026000440 ^@ http://purl.uniprot.org/uniprot/Q2UEX4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the WD repeat MET30/SCONB/SCON-2 family.|||Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.|||Component of the SCF(sconB) E3 ubiquitin ligase complex. http://togogenome.org/gene/510516:AO090010000232 ^@ http://purl.uniprot.org/uniprot/Q2TX95 ^@ Similarity ^@ Belongs to the NmrA-type oxidoreductase family. http://togogenome.org/gene/510516:AO090009000303 ^@ http://purl.uniprot.org/uniprot/Q2UUI3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover (By similarity). Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA (By similarity).|||Belongs to the CCR4/nocturin family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/510516:AO090701000452 ^@ http://purl.uniprot.org/uniprot/Q2U8F3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090003001404 ^@ http://purl.uniprot.org/uniprot/Q2UJ07 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane|||Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. http://togogenome.org/gene/510516:AO090009000333 ^@ http://purl.uniprot.org/uniprot/Q2UUF7 ^@ Similarity ^@ In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. http://togogenome.org/gene/510516:AO090012000154 ^@ http://purl.uniprot.org/uniprot/Q2UDJ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the proteasome inhibitor PI31 family.|||Cytoplasm|||Endoplasmic reticulum|||Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28. http://togogenome.org/gene/510516:AO090020000415 ^@ http://purl.uniprot.org/uniprot/Q2U4B1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090020000024 ^@ http://purl.uniprot.org/uniprot/Q2U594 ^@ Similarity ^@ Belongs to the OSBP family. http://togogenome.org/gene/510516:AO090026000426 ^@ http://purl.uniprot.org/uniprot/Q2UEY6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/510516:AO090005001123 ^@ http://purl.uniprot.org/uniprot/Q2UQS3 ^@ Similarity ^@ Belongs to the APC10 family. http://togogenome.org/gene/510516:AO090023000159 ^@ http://purl.uniprot.org/uniprot/Q2UI80 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 61 family.|||Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM). The genes for catalytic modules and CBMs seem to have evolved separately and have been linked by gene fusion.|||Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds. Involved in the degradation of complex natural cellulosic substrates.|||Secreted http://togogenome.org/gene/510516:AO090113000139 ^@ http://purl.uniprot.org/uniprot/Q2U5H7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090003000175 ^@ http://purl.uniprot.org/uniprot/Q2UM21 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090020000484 ^@ http://purl.uniprot.org/uniprot/Q2U457 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PRP38 family.|||Nucleus|||Required for pre-mRNA splicing. http://togogenome.org/gene/510516:AO090138000008 ^@ http://purl.uniprot.org/uniprot/Q2U216 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||Membrane http://togogenome.org/gene/510516:AO090020000219 ^@ http://purl.uniprot.org/uniprot/Q2U4S7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090020000649 ^@ http://purl.uniprot.org/uniprot/Q2U3R6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090001000141 ^@ http://purl.uniprot.org/uniprot/Q2UP25 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090701000099 ^@ http://purl.uniprot.org/uniprot/Q2U9B3 ^@ Similarity ^@ Belongs to the MNN1/MNT family. http://togogenome.org/gene/510516:AO090001000032 ^@ http://purl.uniprot.org/uniprot/Q2UPC0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ ABC transporter; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411).|||Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.|||Membrane http://togogenome.org/gene/510516:AO090005000134 ^@ http://purl.uniprot.org/uniprot/Q2UT70 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.|||Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with msh2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. Msh3 provides substrate-binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions (By similarity).|||Heterodimer consisting of msh2-msh3 (MutS beta). Forms a ternary complex with MutL alpha (mlh1-pms1) (By similarity).|||Nucleus http://togogenome.org/gene/510516:AO090009000213 ^@ http://purl.uniprot.org/uniprot/Q2UUR1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090023000685 ^@ http://purl.uniprot.org/uniprot/Q2UGW4 ^@ Function|||Similarity ^@ Belongs to the lysophospholipase family.|||Catalyzes the release of fatty acids from lysophospholipids. http://togogenome.org/gene/510516:AO090003001034 ^@ http://purl.uniprot.org/uniprot/Q2UJX5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II.|||Cytoplasm|||Nucleus|||Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/510516:AO090003000490 ^@ http://purl.uniprot.org/uniprot/Q2ULA1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090701000028 ^@ http://purl.uniprot.org/uniprot/Q2U9H6 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.|||Belongs to the URM1 family.|||C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.|||Cytoplasm http://togogenome.org/gene/510516:AO090005001099 ^@ http://purl.uniprot.org/uniprot/Q2UQU3 ^@ Similarity ^@ Belongs to the peptidase C12 family. http://togogenome.org/gene/510516:AO090023000209 ^@ http://purl.uniprot.org/uniprot/Q2UI33 ^@ Similarity ^@ Belongs to the ribose 5-phosphate isomerase family. http://togogenome.org/gene/510516:AO090102000290 ^@ http://purl.uniprot.org/uniprot/Q2UAQ2 ^@ Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily. http://togogenome.org/gene/510516:AO090003000500 ^@ http://purl.uniprot.org/uniprot/Q2UL92 ^@ Similarity ^@ Belongs to the WD repeat CDC20/Fizzy family. http://togogenome.org/gene/510516:AO090166000101 ^@ http://purl.uniprot.org/uniprot/Q2U9L6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TEC1 family.|||Nucleus|||Probable regulator of conidiophore development and conidium maturation (By similarity). http://togogenome.org/gene/510516:AO090012000488 ^@ http://purl.uniprot.org/uniprot/Q2UCQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAF1 family.|||Nucleus http://togogenome.org/gene/510516:AO090005001478 ^@ http://purl.uniprot.org/uniprot/Q2UPW8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRM5 / TYW2 family.|||Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.|||Cytoplasm|||Mitochondrion matrix|||Monomer.|||Nucleus|||Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding. http://togogenome.org/gene/510516:AO090020000564 ^@ http://purl.uniprot.org/uniprot/Q2U3Y7 ^@ Similarity ^@ Belongs to the NmrA-type oxidoreductase family. http://togogenome.org/gene/510516:AO090011000622 ^@ http://purl.uniprot.org/uniprot/Q2U020 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Nucleus http://togogenome.org/gene/510516:AO090120000125 ^@ http://purl.uniprot.org/uniprot/Q2U6R6 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/510516:AO090026000544 ^@ http://purl.uniprot.org/uniprot/Q2UEP0 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/510516:AO090003000208 ^@ http://purl.uniprot.org/uniprot/Q2ULZ5 ^@ Cofactor|||Similarity ^@ Belongs to the 4HPPD family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/510516:AO090010000169 ^@ http://purl.uniprot.org/uniprot/Q2TXF2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily.|||MFS-type transporter; part of the gene cluster that mediates the biosynthesis of oryzines, natural products with an unusual maleidride backbone.|||Membrane http://togogenome.org/gene/510516:AO090023000411 ^@ http://purl.uniprot.org/uniprot/Q2UHK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Membrane http://togogenome.org/gene/510516:AO090138000175 ^@ http://purl.uniprot.org/uniprot/Q2U1M1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090120000055 ^@ http://purl.uniprot.org/uniprot/Q2U6X5 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family. http://togogenome.org/gene/510516:AO090038000344 ^@ http://purl.uniprot.org/uniprot/Q2U2S0 ^@ Similarity ^@ Belongs to the prefoldin subunit alpha family. http://togogenome.org/gene/510516:AO090010000339 ^@ http://purl.uniprot.org/uniprot/Q2TX04 ^@ Similarity ^@ Belongs to the polyketide transferase af380 family. http://togogenome.org/gene/510516:AO090001000214 ^@ http://purl.uniprot.org/uniprot/Q2UNV8 ^@ Similarity ^@ Belongs to the class-II DAHP synthase family. http://togogenome.org/gene/510516:AO090020000634 ^@ http://purl.uniprot.org/uniprot/Q2U3S8 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family. Prx6 subfamily.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/510516:AO090012000251 ^@ http://purl.uniprot.org/uniprot/Q2UDA6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090010000504 ^@ http://purl.uniprot.org/uniprot/Q2TWM1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 1 family.|||Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.|||Secreted http://togogenome.org/gene/510516:AO090701000543 ^@ http://purl.uniprot.org/uniprot/Q2U874 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL24 family. http://togogenome.org/gene/510516:AO090103000037 ^@ http://purl.uniprot.org/uniprot/Q2TZ02 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP14 family.|||Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.|||nucleolus http://togogenome.org/gene/510516:AO090003000193 ^@ http://purl.uniprot.org/uniprot/Q2UM06 ^@ Function|||Similarity ^@ Belongs to the CTR86 family.|||Essential protein which may be involved in threonine biosynthesis. http://togogenome.org/gene/510516:AO090113000148 ^@ http://purl.uniprot.org/uniprot/Q2U5G8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/510516:AO090023000957 ^@ http://purl.uniprot.org/uniprot/Q2UG69 ^@ Similarity ^@ Belongs to the protein prenyltransferase subunit alpha family. http://togogenome.org/gene/510516:AO090005001340 ^@ http://purl.uniprot.org/uniprot/Q2UQ97 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SLD2 family.|||Cytoplasm|||Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity).|||Nucleus http://togogenome.org/gene/510516:AO090012000786 ^@ http://purl.uniprot.org/uniprot/Q2UC14 ^@ Function|||Similarity ^@ Belongs to the POA1 family.|||Highly specific phosphatase involved in the metabolism of ADP-ribose 1''-phosphate (Appr1p) which is produced as a consequence of tRNA splicing. http://togogenome.org/gene/510516:AO090003001305 ^@ http://purl.uniprot.org/uniprot/Q2UJ97 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 27 family.|||Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.|||Secreted http://togogenome.org/gene/510516:AO090103000403 ^@ http://purl.uniprot.org/uniprot/Q2TY39 ^@ Function ^@ Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER. http://togogenome.org/gene/510516:AO090672000009 ^@ http://purl.uniprot.org/uniprot/Q2UG14 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.|||Cytoplasm|||S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha. http://togogenome.org/gene/510516:AO090120000437 ^@ http://purl.uniprot.org/uniprot/Q2U600 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BCP1 family.|||Cytoplasm|||Involved in nuclear export, actin cytoskeleton organization and vesicular transport.|||Nucleus http://togogenome.org/gene/510516:AO090020000640 ^@ http://purl.uniprot.org/uniprot/Q2U3S3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/510516:AO090701000162 ^@ http://purl.uniprot.org/uniprot/Q2U959 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003001277 ^@ http://purl.uniprot.org/uniprot/Q2UJC4 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/510516:AO090026000516 ^@ http://purl.uniprot.org/uniprot/O94183 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NPC2 family.|||Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.|||Cytoplasm|||Cytoplasmic vesicle|||Golgi apparatus|||Monomer. http://togogenome.org/gene/510516:AO090001000145 ^@ http://purl.uniprot.org/uniprot/Q2UP21 ^@ Similarity ^@ Belongs to the peptidase M28 family. http://togogenome.org/gene/510516:AO090001000154 ^@ http://purl.uniprot.org/uniprot/Q2UP12 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/510516:AO090005000716 ^@ http://purl.uniprot.org/uniprot/Q2URR7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KXD1 family.|||Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.|||Endosome http://togogenome.org/gene/510516:AO090011000860 ^@ http://purl.uniprot.org/uniprot/Q2TZG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/510516:AO090010000036 ^@ http://purl.uniprot.org/uniprot/Q2TXR8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090206000110 ^@ http://purl.uniprot.org/uniprot/Q2PIQ5 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/510516:AO090005000158 ^@ http://purl.uniprot.org/uniprot/Q2UT49 ^@ Similarity ^@ Belongs to the polyketide transferase af380 family. http://togogenome.org/gene/510516:AO090120000091 ^@ http://purl.uniprot.org/uniprot/Q2U6U5 ^@ Similarity ^@ Belongs to the V-ATPase E subunit family. http://togogenome.org/gene/510516:AO090001000490 ^@ http://purl.uniprot.org/uniprot/Q2UN63 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.|||Endoplasmic reticulum membrane|||Required for N-linked oligosaccharide assembly. Has a role in the last step of the synthesis of the Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. http://togogenome.org/gene/510516:AO090026000382 ^@ http://purl.uniprot.org/uniprot/Q2UF21 ^@ Similarity ^@ Belongs to the trichodiene synthase family. http://togogenome.org/gene/510516:AO090020000425 ^@ http://purl.uniprot.org/uniprot/Q2U4A2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NSE4 family.|||Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.|||Component of the SMC5-SMC6 complex.|||Nucleus http://togogenome.org/gene/510516:AO090012000653 ^@ http://purl.uniprot.org/uniprot/Q2UCC3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.|||Cytoplasm|||S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'. http://togogenome.org/gene/510516:AO090003001495 ^@ http://purl.uniprot.org/uniprot/Q2UIS8 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. http://togogenome.org/gene/510516:AO090120000316 ^@ http://purl.uniprot.org/uniprot/Q2U6A7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. http://togogenome.org/gene/510516:AO090005000972 ^@ http://purl.uniprot.org/uniprot/Q2UR48 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/510516:AO090009000594 ^@ http://purl.uniprot.org/uniprot/Q2UTU0 ^@ Similarity ^@ Belongs to the LTV1 family. http://togogenome.org/gene/510516:AO090003000068 ^@ http://purl.uniprot.org/uniprot/Q2UMB2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/510516:AO090005001291 ^@ http://purl.uniprot.org/uniprot/Q2UQD8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP5/NOP56 family.|||Required for pre-18S rRNA processing. May bind microtubules.|||nucleolus http://togogenome.org/gene/510516:AO090120000433 ^@ http://purl.uniprot.org/uniprot/Q2U604 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090120000280 ^@ http://purl.uniprot.org/uniprot/Q2U6D9 ^@ Similarity ^@ Belongs to the alkaline phosphatase family. http://togogenome.org/gene/510516:AO090005000962 ^@ http://purl.uniprot.org/uniprot/Q2UR57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090010000466 ^@ http://purl.uniprot.org/uniprot/Q2TWQ4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS12 family. http://togogenome.org/gene/510516:AO090010000165 ^@ http://purl.uniprot.org/uniprot/Q2TXF6 ^@ Function ^@ Ankyrin repeat domain-containing protein; part of the gene cluster that mediates the biosynthesis of oryzines, natural products with an unusual maleidride backbone (PubMed:30104550). The two subunits of the fungal fatty acid synthase oryfasA and oryfasB probably form octenoic acid (Probable). This fatty acid is most likely activated by the acyl-CoA ligase oryP to give octenyl-CoA before the citrate synthase-like protein oryE catalyzes condensation with oxaloacetate to form tricarboxylic acid (Probable). The next steps of the pathways are conjectural, but a favorite possible route has been proposed, beginning with decarboxylation and concomitant dehydration by the decarboxylase oryM, followed by tautomerization, which may lead to the production of a diene intermediate (Probable). Reduction of this diene intermediate could give the known metabolite piliformic acid (Probable). On the pathway to oryzine B and oryzine A, however, hydroxylation of the diene by the alpha-ketoglutarate-dependent dioxygenase oryG and lactonisation by the lactonohydrolases oryH or oryL could give oryzine B directly (Probable). Finally, enoyl reduction by the dehydrogenase oryD would then convert oryzine B into oryzine A (Probable). http://togogenome.org/gene/510516:AO090012000205 ^@ http://purl.uniprot.org/uniprot/Q2UDE4 ^@ Similarity ^@ Belongs to the HMBS family. http://togogenome.org/gene/510516:AO090005001095 ^@ http://purl.uniprot.org/uniprot/Q2UQU7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000073 ^@ http://purl.uniprot.org/uniprot/Q2UTC6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090038000578 ^@ http://purl.uniprot.org/uniprot/Q2U270 ^@ Similarity ^@ Belongs to the indoleamine 2,3-dioxygenase family. http://togogenome.org/gene/510516:AO090001000091 ^@ http://purl.uniprot.org/uniprot/Q2UP69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/510516:AO090138000195 ^@ http://purl.uniprot.org/uniprot/Q2U1K9 ^@ Similarity ^@ Belongs to the isochorismatase family. http://togogenome.org/gene/510516:AO090010000471 ^@ http://purl.uniprot.org/uniprot/Q2TWQ0 ^@ Similarity ^@ Belongs to the GHMP kinase family. Mevalonate kinase subfamily. http://togogenome.org/gene/510516:AO090020000203 ^@ http://purl.uniprot.org/uniprot/Q2U4U3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090023000225 ^@ http://purl.uniprot.org/uniprot/Q2UI18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ORC6 family.|||Nucleus http://togogenome.org/gene/510516:AO090005001300 ^@ http://purl.uniprot.org/uniprot/Q2UQD0 ^@ Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. http://togogenome.org/gene/510516:AO090010000620 ^@ http://purl.uniprot.org/uniprot/Q2TWC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-93 family.|||Membrane http://togogenome.org/gene/510516:AO090003000913 ^@ http://purl.uniprot.org/uniprot/Q2UK85 ^@ Similarity ^@ Belongs to the SEC3 family. http://togogenome.org/gene/510516:AO090005000690 ^@ http://purl.uniprot.org/uniprot/Q2URU1 ^@ Similarity ^@ Belongs to the NRP synthetase family. http://togogenome.org/gene/510516:AO090012000647 ^@ http://purl.uniprot.org/uniprot/Q2UCC6 ^@ Similarity ^@ Belongs to the KTI12 family. http://togogenome.org/gene/510516:AO090005000576 ^@ http://purl.uniprot.org/uniprot/Q2US45 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.|||Phosphorylation of the TEDS site (Ser-370) is required for the polarization of the actin cytoskeleton. Phosphorylation probably activates the myosin-I ATPase activity (By similarity).|||The myosin motor domain displays actin-stimulated ATPase activity and generates a mechanochemical force.|||The tail domain participates in molecular interactions that specify the role of the motor domain (By similarity). It is composed of several tail homology (TH) domains, namely a putative phospholipid-binding myosin tail domain (also named TH1), an Ala- and Pro-rich domain (TH2), followed by an SH3 domain and a C-terminal acidic domain (TH3).|||Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex. Plays an important role in polarized growth, spore germination, hyphal morphogenesis, and septal wall formation (By similarity).|||actin patch http://togogenome.org/gene/510516:AO090103000360 ^@ http://purl.uniprot.org/uniprot/Q2TY78 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/510516:AO090003001432 ^@ http://purl.uniprot.org/uniprot/Q2UIX9 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/510516:AO090038000507 ^@ http://purl.uniprot.org/uniprot/Q2U2C6 ^@ Similarity ^@ Belongs to the PhyH family. http://togogenome.org/gene/510516:AO090003000404 ^@ http://purl.uniprot.org/uniprot/Q2ULH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.|||cytoskeleton http://togogenome.org/gene/510516:AO090003001387 ^@ http://purl.uniprot.org/uniprot/Q2UJ20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090026000338 ^@ http://purl.uniprot.org/uniprot/Q2UF59 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxin-14 family.|||Component of the peroxisomal translocation machinery.|||Peroxisome membrane http://togogenome.org/gene/510516:AO090009000552 ^@ http://purl.uniprot.org/uniprot/Q2UTX7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090001000714 ^@ http://purl.uniprot.org/uniprot/Q2UML1 ^@ Function|||Similarity ^@ Belongs to the JHDM1 histone demethylase family.|||Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. http://togogenome.org/gene/510516:AO090003000454 ^@ http://purl.uniprot.org/uniprot/Q2ULD4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Ran family.|||GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.|||Nucleus http://togogenome.org/gene/510516:AO090701000490 ^@ http://purl.uniprot.org/uniprot/Q2U8B9 ^@ Cofactor|||PTM|||Similarity ^@ Belongs to the copper/topaquinone oxidase family.|||Contains 1 topaquinone per subunit.|||Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. http://togogenome.org/gene/510516:AO090023000750 ^@ http://purl.uniprot.org/uniprot/Q2UGR0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGU family.|||Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/510516:AO090103000329 ^@ http://purl.uniprot.org/uniprot/Q2TYA4 ^@ Function|||Similarity ^@ Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/510516:AO090005001241 ^@ http://purl.uniprot.org/uniprot/Q2UQH8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SSH4 family.|||Components of the endosome-vacuole trafficking pathway that regulates nutrient transport. May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane.|||Endosome membrane|||Membrane|||Vacuole membrane http://togogenome.org/gene/510516:AO090009000516 ^@ http://purl.uniprot.org/uniprot/Q2UU05 ^@ Similarity ^@ Belongs to the FMO family. http://togogenome.org/gene/510516:AO090038000365 ^@ http://purl.uniprot.org/uniprot/Q2U2Q1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090012000932 ^@ http://purl.uniprot.org/uniprot/Q2UBN2 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family. http://togogenome.org/gene/510516:AO090026000584 ^@ http://purl.uniprot.org/uniprot/Q2UEK3 ^@ Disruption Phenotype|||Function|||Induction|||Similarity ^@ Belongs to the cytochrome P450 family.|||Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of astellolides, drimane-type sesquiterpene esters that show antimicrobial, anti-inflammatory, and anti-tumor activities (PubMed:27628599). The first step in astellolide biosynthesis is performed by the sesquiterpene cyclase astC that catalyzes the formation of drimanyl pyrophosphate from farnesyl pyrophosphate (PubMed:27628599). Drimanyl pyrophosphate is then dephosphorylated by the sesquiterpene phosphatase astI to produce drimanyl monophosphate which is further dephosphorylated to drim-8-ene-11-ol by atsK (PubMed:27628599). Drim-8-ene-11-ol is converted to confertifolin, probably by the cytochrome P450 monooxygenase astD and/or the dehydrogenase astE (PubMed:27628599). The cytochrome P450 monooxygenases astB, astF and astJ then hydroxylate confertifolin at C6, C14, or C15 to form trihydroxy confertifolin (PubMed:27628599). The nonribosomal peptide synthetase astA catalyzes ester bond formation between trihydroxy contifolin and benzoic acid (BA) or 4-hydroxy benzoic acid (4HBA), leading to the formation of dideacetyl astellolides A and B, respectively (PubMed:27628599). Finally, the O-acetyltransferase astG converts dideacetyl astellolides A and B into deacetyl astellolides A and B (PubMed:27628599).|||Expression is regulated by the secondary metabolite regulator cclA.|||Impairs the production of trihydroxy confertifolin and deacetyl astellolides A and B. http://togogenome.org/gene/510516:AO090102000639 ^@ http://purl.uniprot.org/uniprot/Q2U9W4 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/510516:AO090038000175 ^@ http://purl.uniprot.org/uniprot/Q2U360 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 12 (cellulase H) family. http://togogenome.org/gene/510516:AO090023000050 ^@ http://purl.uniprot.org/uniprot/Q2UIH8 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/510516:AO090012000298 ^@ http://purl.uniprot.org/uniprot/Q2UD66 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 51 family. http://togogenome.org/gene/510516:AO090003000325 ^@ http://purl.uniprot.org/uniprot/Q2ULP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090009000068 ^@ http://purl.uniprot.org/uniprot/Q2UV31 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000639 ^@ http://purl.uniprot.org/uniprot/Q2URY6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/510516:AO090701000748 ^@ http://purl.uniprot.org/uniprot/Q2U7Q3 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/510516:AO090001000408 ^@ http://purl.uniprot.org/uniprot/Q2UND6 ^@ Similarity ^@ Belongs to the class-A beta-lactamase family. http://togogenome.org/gene/510516:AO090005000038 ^@ http://purl.uniprot.org/uniprot/Q2UTF6 ^@ Similarity ^@ Belongs to the MSOX/MTOX family. http://togogenome.org/gene/510516:AO090038000119 ^@ http://purl.uniprot.org/uniprot/Q2U3A6 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/510516:AO090026000599 ^@ http://purl.uniprot.org/uniprot/Q2UEJ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COPG family.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/510516:AO090120000495 ^@ http://purl.uniprot.org/uniprot/Q2U5V6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with the pre-60S ribosomal particle.|||Belongs to the universal ribosomal protein uL10 family.|||Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.|||Cytoplasm|||nucleolus http://togogenome.org/gene/510516:AO090009000330 ^@ http://purl.uniprot.org/uniprot/Q2UUF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Membrane http://togogenome.org/gene/510516:AO090102000146 ^@ http://purl.uniprot.org/uniprot/Q2UB20 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol (By similarity).|||Belongs to the ALG6/ALG8 glucosyltransferase family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/510516:AO090003001139 ^@ http://purl.uniprot.org/uniprot/Q2UJN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the steroid 5-alpha reductase family.|||Membrane http://togogenome.org/gene/510516:AO090001000736 ^@ http://purl.uniprot.org/uniprot/Q2UMJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase epsilon subunit B family.|||Nucleus http://togogenome.org/gene/510516:AO090023000944 ^@ http://purl.uniprot.org/uniprot/P0C1B3 ^@ Biotechnology|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family.|||Binds 2 calcium ions per subunit (PubMed:6609921, PubMed:9283074, PubMed:16880540). Calcium is inhibitory at high concentrations.|||Monomer.|||Secreted|||Used in the brewing industry to increase the fermentability of beer worts (including those made from unmalted cereals), in the starch industry to make high maltose and high DE syrups (starch saccharification), in the alcohol industry to reduce fermentation time, in the cereal food industry for flour supplementation and improvement of chilled and frozen dough, and in the forestry industry for low-temperature modification of starch. Sold under the name Fungamyl by Novozymes. http://togogenome.org/gene/510516:AO090038000540 ^@ http://purl.uniprot.org/uniprot/Q2U2A4 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/510516:AO090003000403 ^@ http://purl.uniprot.org/uniprot/Q2ULI0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SEC23/SEC24 family. SEC24 subfamily.|||COPII-coated vesicle membrane|||Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).|||Cytoplasm|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||The COPII coat is composed of at least 5 proteins: the sec23/24 complex, the sec13/31 complex, and the protein sar1. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. http://togogenome.org/gene/510516:AO090009000217 ^@ http://purl.uniprot.org/uniprot/Q2UUQ7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090026000551 ^@ http://purl.uniprot.org/uniprot/Q2UEN4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the actin family.|||Nucleus|||Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. http://togogenome.org/gene/510516:AO090010000067 ^@ http://purl.uniprot.org/uniprot/Q2TXP3 ^@ Similarity ^@ Belongs to the proline racemase family. http://togogenome.org/gene/510516:AO090120000245 ^@ http://purl.uniprot.org/uniprot/Q2U6G6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TIM50 family.|||Component of the TIM23 complex.|||Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090003000572 ^@ http://purl.uniprot.org/uniprot/Q2UL28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/510516:AO090026000811 ^@ http://purl.uniprot.org/uniprot/Q2UE04 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit D family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm|||The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.|||mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs. http://togogenome.org/gene/510516:AO090010000722 ^@ http://purl.uniprot.org/uniprot/Q2TW34 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxidase family. Peroxidase/catalase subfamily.|||Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per monomer.|||Cytoplasm|||Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.|||Homodimer or homotetramer. http://togogenome.org/gene/510516:AO090005001518 ^@ http://purl.uniprot.org/uniprot/Q2UPT4 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/510516:AO090010000769 ^@ http://purl.uniprot.org/uniprot/Q2TVY7 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the VPS10-related sortilin family.|||Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment.|||Present with 7210 molecules/cell in log phase SD medium.|||Prevacuolar compartment membrane|||The lumenal domain contains two regions of approximately 650 AA that exhibit 20% identity. The cytoplasmic domain may serve as a Golgi retention/recycling signal.|||trans-Golgi network membrane http://togogenome.org/gene/510516:AO090012000526 ^@ http://purl.uniprot.org/uniprot/Q2UCM4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/510516:AO090038000135 ^@ http://purl.uniprot.org/uniprot/Q2U391 ^@ Function|||Similarity ^@ Belongs to the HTP reductase family.|||Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate. http://togogenome.org/gene/510516:AO090010000746 ^@ http://purl.uniprot.org/uniprot/P36914 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 15 family. http://togogenome.org/gene/510516:AO090003001296 ^@ http://purl.uniprot.org/uniprot/Q2UJA6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ZIP transporter (TC 2.A.5) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/510516:AO090001000038 ^@ http://purl.uniprot.org/uniprot/Q2UPB4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer.|||Thioredoxin reductase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411). The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411). One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411). After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411). In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411). Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411). http://togogenome.org/gene/510516:AO090011000806 ^@ http://purl.uniprot.org/uniprot/Q2TZL4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090012000261 ^@ http://purl.uniprot.org/uniprot/Q2UD99 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFIIA subunit 2 family.|||Nucleus|||TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity. http://togogenome.org/gene/510516:AO090120000399 ^@ http://purl.uniprot.org/uniprot/Q2U634 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the replication factor A protein 3 family.|||Nucleus http://togogenome.org/gene/510516:AO090102000593 ^@ http://purl.uniprot.org/uniprot/Q2UA05 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.|||Cytoplasm|||Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.|||Signal recognition particle consists of a 7S RNA molecule and at least six protein subunits. http://togogenome.org/gene/510516:AO090102000081 ^@ http://purl.uniprot.org/uniprot/Q2UB74 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090026000787 ^@ http://purl.uniprot.org/uniprot/Q2UE25 ^@ Similarity ^@ Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family. http://togogenome.org/gene/510516:AO090012000295 ^@ http://purl.uniprot.org/uniprot/Q2UD69 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090023000106 ^@ http://purl.uniprot.org/uniprot/Q2UID0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090023000083 ^@ http://purl.uniprot.org/uniprot/Q2UIE6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 16 family.|||Cell membrane|||Mixed-linked glucanase involved in the degradation of complex natural cellulosic substrates. http://togogenome.org/gene/510516:AO090012000389 ^@ http://purl.uniprot.org/uniprot/Q2UCZ1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/510516:AO090011000607 ^@ http://purl.uniprot.org/uniprot/Q2U033 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RPAP2 family.|||Nucleus|||Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation. http://togogenome.org/gene/510516:AO090038000550 ^@ http://purl.uniprot.org/uniprot/Q2U295 ^@ Similarity ^@ Belongs to the NRP synthetase family. http://togogenome.org/gene/510516:AO090003000831 ^@ http://purl.uniprot.org/uniprot/Q2UKF3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Binds 1 FAD per monomer.|||Irreversibly catalyzes the reduction of fumarate to succinate. http://togogenome.org/gene/510516:AO090003001162 ^@ http://purl.uniprot.org/uniprot/Q2UJL5 ^@ Similarity ^@ Belongs to the SEC6 family. http://togogenome.org/gene/510516:AO090026000576 ^@ http://purl.uniprot.org/uniprot/Q2UEL0 ^@ Function|||Induction|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily.|||Expression is regulated by the secondary metabolite regulator cclA.|||Sesquiterpene phosphatase; part of the gene cluster that mediates the biosynthesis of astellolides, drimane-type sesquiterpene esters that show antimicrobial, anti-inflammatory, and anti-tumor activities (PubMed:27628599). The first step in astellolide biosynthesis is performed by the sesquiterpene cyclase astC that catalyzes the formation of drimanyl pyrophosphate from farnesyl pyrophosphate (PubMed:27628599). Drimanyl pyrophosphate is then dephosphorylated by the sesquiterpene phosphatase astI to produce drimanyl monophosphate which is further dephosphorylated to drim-8-ene-11-ol by atsK (PubMed:27628599). Drim-8-ene-11-ol is converted to confertifolin, probably by the cytochrome P450 monooxygenase astD and/or the dehydrogenase astE (PubMed:27628599). The cytochrome P450 monooxygenases astB, astF and astJ then hydroxylate confertifolin at C6, C14, or C15 to form trihydroxy confertifolin (PubMed:27628599). The nonribosomal peptide synthetase astA catalyzes ester bond formation between trihydroxy contifolin and benzoic acid (BA) or 4-hydroxy benzoic acid (4HBA), leading to the formation of dideacetyl astellolides A and B, respectively (PubMed:27628599). Finally, the O-acetyltransferase astG converts dideacetyl astellolides A and B into deacetyl astellolides A and B (PubMed:27628599). http://togogenome.org/gene/510516:AO090011000768 ^@ http://purl.uniprot.org/uniprot/Q2TZQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/510516:AO090010000098 ^@ http://purl.uniprot.org/uniprot/Q2TXL4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090020000041 ^@ http://purl.uniprot.org/uniprot/Q2U577 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NadC/ModD family.|||Hexamer formed by 3 homodimers.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/510516:AO090005000367 ^@ http://purl.uniprot.org/uniprot/Q2USM5 ^@ Function|||Similarity ^@ Belongs to the choline monooxygenase family.|||Catalyzes the first step of the osmoprotectant glycine betaine synthesis. http://togogenome.org/gene/510516:AO090003000697 ^@ http://purl.uniprot.org/uniprot/Q2UKS1 ^@ Cofactor|||Similarity ^@ Belongs to the arginase family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/510516:AO090103000336 ^@ http://purl.uniprot.org/uniprot/Q2TY97 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/510516:AO090001000484 ^@ http://purl.uniprot.org/uniprot/Q2UN69 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aconitase/IPM isomerase family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Mitochondrion http://togogenome.org/gene/510516:AO090005000551 ^@ http://purl.uniprot.org/uniprot/Q2US66 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family. http://togogenome.org/gene/510516:AO090003001144 ^@ http://purl.uniprot.org/uniprot/Q2UJN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VTI1 family.|||Membrane http://togogenome.org/gene/510516:AO090020000552 ^@ http://purl.uniprot.org/uniprot/Q2U3Z8 ^@ Similarity|||Subunit ^@ Belongs to the PPP phosphatase family. PP-2B subfamily.|||Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity. http://togogenome.org/gene/510516:AO090026000523 ^@ http://purl.uniprot.org/uniprot/Q2UEQ6 ^@ Similarity ^@ Belongs to the glycosyltransferase group 1 family. http://togogenome.org/gene/510516:AO090005000604 ^@ http://purl.uniprot.org/uniprot/Q2US19 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ATPase B chain family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. In yeast, the dimeric form of ATP synthase consists of 17 polypeptides: alpha, beta, gamma, delta, epsilon, 4 (B), 5 (OSCP), 6 (A), 8, 9 (C), d, E (Tim11), f, g, h, i/j and k.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.|||Mitochondrion|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090023000816 ^@ http://purl.uniprot.org/uniprot/Q2UGJ7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48A family.|||Binds 1 zinc ion per subunit.|||Endoplasmic reticulum membrane|||Proteolytically removes the C-terminal three residues of farnesylated proteins. http://togogenome.org/gene/510516:AO090001000034 ^@ http://purl.uniprot.org/uniprot/Q2UPB8 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||Part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411). The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411). One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411). After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411). In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411). Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411). http://togogenome.org/gene/510516:AO090003000164 ^@ http://purl.uniprot.org/uniprot/Q2UM29 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/510516:AO090103000020 ^@ http://purl.uniprot.org/uniprot/Q2TZ16 ^@ Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. http://togogenome.org/gene/510516:AO090023000551 ^@ http://purl.uniprot.org/uniprot/Q2UH81 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/510516:AO090038000370 ^@ http://purl.uniprot.org/uniprot/Q2U2P7 ^@ Similarity ^@ Belongs to the sirtuin family. Class I subfamily. http://togogenome.org/gene/510516:AO090011000679 ^@ http://purl.uniprot.org/uniprot/Q2TZX5 ^@ Miscellaneous|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer.|||In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes. http://togogenome.org/gene/510516:AO090020000096 ^@ http://purl.uniprot.org/uniprot/Q2U532 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/510516:AO090001000547 ^@ http://purl.uniprot.org/uniprot/Q2UN09 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/510516:AO090038000425 ^@ http://purl.uniprot.org/uniprot/Q2U2K1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/510516:AO090009000228 ^@ http://purl.uniprot.org/uniprot/Q2UUQ0 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/510516:AO090005000219 ^@ http://purl.uniprot.org/uniprot/Q2UT04 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090023000542 ^@ http://purl.uniprot.org/uniprot/Q2UH88 ^@ Similarity ^@ Belongs to the asaB hydroxylase/desaturase family. http://togogenome.org/gene/510516:AO090005000698 ^@ http://purl.uniprot.org/uniprot/Q2URT3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/510516:AO090005000033 ^@ http://purl.uniprot.org/uniprot/Q2UTG1 ^@ Similarity ^@ Belongs to the amino acid/polyamine transporter 2 family. http://togogenome.org/gene/510516:AO090005000850 ^@ http://purl.uniprot.org/uniprot/Q2URF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090003001121 ^@ http://purl.uniprot.org/uniprot/Q2UJQ2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/510516:AO090026000103 ^@ http://purl.uniprot.org/uniprot/Q2UFR7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 11 (cellulase G) family.|||Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.|||Secreted http://togogenome.org/gene/510516:AO090012000434 ^@ http://purl.uniprot.org/uniprot/Q2UCV3 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. Fibrillarin family. http://togogenome.org/gene/510516:AO090023000719 ^@ http://purl.uniprot.org/uniprot/Q2UGT5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 1 family.|||Binds 1 zinc ion per subunit.|||Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. http://togogenome.org/gene/510516:AO090005001183 ^@ http://purl.uniprot.org/uniprot/Q2UQM5 ^@ Similarity ^@ Belongs to the four-carbon acid sugar kinase family. http://togogenome.org/gene/510516:AO090005000630 ^@ http://purl.uniprot.org/uniprot/Q2URZ3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EROs family.|||Endoplasmic reticulum membrane|||May function both as a monomer and a homodimer. http://togogenome.org/gene/510516:AO090102000366 ^@ http://purl.uniprot.org/uniprot/Q2UAJ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Component of the MCM2-7 complex.|||Nucleus http://togogenome.org/gene/510516:AO090011000424 ^@ http://purl.uniprot.org/uniprot/Q2U0I7 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/510516:AO090003000656 ^@ http://purl.uniprot.org/uniprot/Q2UKV7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ASF1 family.|||Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.|||Interacts with histone H3 and histone H4.|||Nucleus http://togogenome.org/gene/510516:AO090001000295 ^@ http://purl.uniprot.org/uniprot/Q2UNN3 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/510516:AO090011000367 ^@ http://purl.uniprot.org/uniprot/Q2U0N4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL22 family. http://togogenome.org/gene/510516:AO090003001019 ^@ http://purl.uniprot.org/uniprot/Q2UJY9 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/510516:AO090026000102 ^@ http://purl.uniprot.org/uniprot/Q2UFR8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 12 (cellulase H) family. http://togogenome.org/gene/510516:AO090011000576 ^@ http://purl.uniprot.org/uniprot/Q2U059 ^@ Function|||Similarity|||Subunit ^@ Belongs to the mannitol dehydrogenase family.|||Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway.|||Monomer. http://togogenome.org/gene/510516:AO090102000102 ^@ http://purl.uniprot.org/uniprot/Q2UB55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fungal Na(+)/H(+) exchanger family.|||Membrane http://togogenome.org/gene/510516:AO090023000076 ^@ http://purl.uniprot.org/uniprot/Q2UIF3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 35 family. http://togogenome.org/gene/510516:AO090701000675 ^@ http://purl.uniprot.org/uniprot/Q2U7W5 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/510516:AO090026000562 ^@ http://purl.uniprot.org/uniprot/Q2UEM3 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/510516:AO090120000226 ^@ http://purl.uniprot.org/uniprot/Q2U6I2 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. http://togogenome.org/gene/510516:AO090701000758 ^@ http://purl.uniprot.org/uniprot/Q2U7P3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/510516:AO090038000426 ^@ http://purl.uniprot.org/uniprot/Q2U2K0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090020000339 ^@ http://purl.uniprot.org/uniprot/Q2U4H7 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/510516:AO090038000053 ^@ http://purl.uniprot.org/uniprot/Q2U3G0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090206000067 ^@ http://purl.uniprot.org/uniprot/Q2PIT8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.|||Cytoplasm|||Heterodimer of a catalytic subunit and an accessory subunit. http://togogenome.org/gene/510516:AO090012001005 ^@ http://purl.uniprot.org/uniprot/Q2UBG9 ^@ Function|||Similarity ^@ Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.|||Belongs to the peptidase M67A family. http://togogenome.org/gene/510516:AO090003000737 ^@ http://purl.uniprot.org/uniprot/Q2UKN4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090001000175 ^@ http://purl.uniprot.org/uniprot/Q2UNZ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090102000058 ^@ http://purl.uniprot.org/uniprot/Q2UB96 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/510516:AO090012000858 ^@ http://purl.uniprot.org/uniprot/Q2UBU7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily. http://togogenome.org/gene/510516:AO090003000791 ^@ http://purl.uniprot.org/uniprot/Q2UKI6 ^@ Similarity ^@ Belongs to the CTAG/PCC1 family. http://togogenome.org/gene/510516:AO090010000171 ^@ http://purl.uniprot.org/uniprot/Q2TXF0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.|||Fatty acid synthase alpha subunit; part of the gene cluster that mediates the biosynthesis of oryzines, natural products with an unusual maleidride backbone (PubMed:30104550). The two subunits of the fungal fatty acid synthase oryfasA and oryfasB probably form octenoic acid (Probable). This fatty acid is most likely activated by the acyl-CoA ligase oryP to give octenyl-CoA before the citrate synthase-like protein oryE catalyzes condensation with oxaloacetate to form tricarboxylic acid (Probable). The next steps of the pathways are conjectural, but a favorite possible route has been proposed, beginning with decarboxylation and concomitant dehydration by the decarboxylase oryM, followed by tautomerization, which may lead to the production of a diene intermediate (Probable). Reduction of this diene intermediate could give the known metabolite piliformic acid (Probable). On the pathway to oryzine B and oryzine A, however, hydroxylation of the diene by the alpha-ketoglutarate-dependent dioxygenase oryG and lactonisation by the lactonohydrolases oryH or oryL could give oryzine B directly (Probable). Finally, enoyl reduction by the dehydrogenase oryD would then convert oryzine B into oryzine A (Probable).|||Fatty acid synthase is composed of alpha and beta subunits. http://togogenome.org/gene/510516:AO090005001272 ^@ http://purl.uniprot.org/uniprot/Q2UQF5 ^@ Similarity ^@ Belongs to the cytochrome c oxidase subunit 6B family. http://togogenome.org/gene/510516:AO090005000694 ^@ http://purl.uniprot.org/uniprot/Q2URT7 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/510516:AO090010000543 ^@ http://purl.uniprot.org/uniprot/Q2TWI4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005001315 ^@ http://purl.uniprot.org/uniprot/Q2UQB8 ^@ Similarity ^@ In the C-terminal section; belongs to the TrpB family.|||In the N-terminal section; belongs to the TrpA family. http://togogenome.org/gene/510516:AO090026000732 ^@ http://purl.uniprot.org/uniprot/Q2UE77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELP4 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/510516:AO090020000347 ^@ http://purl.uniprot.org/uniprot/Q2U4H0 ^@ Similarity ^@ Belongs to the PAPS reductase family. CysH subfamily. http://togogenome.org/gene/510516:AO090009000536 ^@ http://purl.uniprot.org/uniprot/Q2UTY8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090026000719 ^@ http://purl.uniprot.org/uniprot/Q2UE88 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090003000205 ^@ http://purl.uniprot.org/uniprot/Q2ULZ8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090005001458 ^@ http://purl.uniprot.org/uniprot/Q2UPY6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/510516:AO090003001436 ^@ http://purl.uniprot.org/uniprot/Q2UIX6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090120000462 ^@ http://purl.uniprot.org/uniprot/Q2U5Y0 ^@ Similarity ^@ Belongs to the EME1/MMS4 family. http://togogenome.org/gene/510516:AO090011000301 ^@ http://purl.uniprot.org/uniprot/Q2U0U5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090003000954 ^@ http://purl.uniprot.org/uniprot/Q2UK47 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090012000537 ^@ http://purl.uniprot.org/uniprot/Q2UCL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PTPA-type PPIase family.|||Cytoplasm|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity). http://togogenome.org/gene/510516:AO090003000689 ^@ http://purl.uniprot.org/uniprot/Q2UKS9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit E family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/510516:AO090012000135 ^@ http://purl.uniprot.org/uniprot/Q2UDK7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 3 family.|||Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090102000114 ^@ http://purl.uniprot.org/uniprot/Q2UB45 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NIP7 family.|||Interacts with pre-ribosome complex.|||Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.|||nucleolus http://togogenome.org/gene/510516:AO090038000517 ^@ http://purl.uniprot.org/uniprot/Q2U2C0 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily. http://togogenome.org/gene/510516:AO090001000659 ^@ http://purl.uniprot.org/uniprot/Q2UMQ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||nucleolus http://togogenome.org/gene/510516:AO090009000688 ^@ http://purl.uniprot.org/uniprot/Q2UTL1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TPT transporter family. SLC35D subfamily.|||Cytoplasmic vesicle membrane|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Homooligomer.|||Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen. http://togogenome.org/gene/510516:AO090023000899 ^@ http://purl.uniprot.org/uniprot/Q2UGB9 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/510516:AO090102000168 ^@ http://purl.uniprot.org/uniprot/Q2UAZ8 ^@ Disruption Phenotype|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of 2,4'-dihydroxy-3'-methoxypropiophenone (PubMed:32885554). The first step of the pathway is the conversion of acetate into acetyl-CoA by the acyl-CoA ligase ppsA (PubMed:32885554). Acetyl-CoA is then used as a starter unit by the polyketide synthase ppsB and condensed with 4 malonyl-CoA unit to produce the pentaketide backbone (PubMed:32885554). During polyketide extension, the polykedite chain is probably reduced and dehydrated by the KR and PT domains, respectively (Probable). O-methylation seems to be catalyzed by an unknown methyltransferase rather than by the CMeT domain of ppsB (Probable). Two hydroxylations and one further decarboxylation step catalyzed by yet unknown enzymes are then required to yield 4'-hydroxy-3'-methoxypropiophenone (Probable). PpsC functions as a carrier protein to transport 4'-hydroxy-3'-methoxypropiophenone to a specific cell compartment in which 4'-hydroxy-3'-methoxypropiophenone is hydroxylated to 2,4'-dihydroxy-3'-methoxypropiophenone by a still to be identified enzyme (PubMed:32885554).|||Does not affecct the production of 2,4'-dihydroxy-3'-methoxypropiophenone or 4'-hydroxy-3'-methoxypropiophenone.|||Membrane http://togogenome.org/gene/510516:AO090020000162 ^@ http://purl.uniprot.org/uniprot/Q2U4X6 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/510516:AO090701000725 ^@ http://purl.uniprot.org/uniprot/Q2U7S1 ^@ Similarity ^@ Belongs to the PdxS/SNZ family. http://togogenome.org/gene/510516:AO090103000401 ^@ http://purl.uniprot.org/uniprot/Q2TY41 ^@ Cofactor|||PTM|||Similarity ^@ Belongs to the copper/topaquinone oxidase family.|||Contains 1 topaquinone per subunit.|||Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. http://togogenome.org/gene/510516:AO090005000840 ^@ http://purl.uniprot.org/uniprot/Q2URG3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/510516:AO090012000561 ^@ http://purl.uniprot.org/uniprot/Q2UCJ5 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090003000418 ^@ http://purl.uniprot.org/uniprot/Q2ULG7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS17 family. http://togogenome.org/gene/510516:AO090011000929 ^@ http://purl.uniprot.org/uniprot/Q2TZA9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.|||Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Vacuole membrane http://togogenome.org/gene/510516:AO090003000539 ^@ http://purl.uniprot.org/uniprot/Q2UL59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COG8 family.|||Membrane http://togogenome.org/gene/510516:AO090003001063 ^@ http://purl.uniprot.org/uniprot/Q2UJV0 ^@ Similarity ^@ Belongs to the TFP11/STIP family. http://togogenome.org/gene/510516:AO090038000563 ^@ http://purl.uniprot.org/uniprot/Q2U284 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.|||Nucleus http://togogenome.org/gene/510516:AO090120000074 ^@ http://purl.uniprot.org/uniprot/Q2U6W1 ^@ Function|||Similarity ^@ Belongs to the fatty acyl-CoA reductase family.|||Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. http://togogenome.org/gene/510516:AO090102000626 ^@ http://purl.uniprot.org/uniprot/Q2U9X5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/510516:AO090010000518 ^@ http://purl.uniprot.org/uniprot/Q2TWK8 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/510516:AO090010000587 ^@ http://purl.uniprot.org/uniprot/Q2TWF1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090005000727 ^@ http://purl.uniprot.org/uniprot/Q2URQ7 ^@ Similarity ^@ Belongs to the G-alpha family. G(q) subfamily. http://togogenome.org/gene/510516:AO090012000974 ^@ http://purl.uniprot.org/uniprot/Q2UBJ4 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/510516:AO090012000402 ^@ http://purl.uniprot.org/uniprot/Q2UCY0 ^@ Subcellular Location Annotation ^@ Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090003000369 ^@ http://purl.uniprot.org/uniprot/Q2ULL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the epsin family.|||Membrane http://togogenome.org/gene/510516:AO090003001344 ^@ http://purl.uniprot.org/uniprot/Q2UJ61 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005001650 ^@ http://purl.uniprot.org/uniprot/Q2UPG6 ^@ Function|||Similarity ^@ Belongs to the exportin family.|||tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease. http://togogenome.org/gene/510516:AO090038000132 ^@ http://purl.uniprot.org/uniprot/Q2U394 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/510516:AO090003000939 ^@ http://purl.uniprot.org/uniprot/Q2UK62 ^@ Similarity ^@ Belongs to the VPS52 family. http://togogenome.org/gene/510516:AO090005000455 ^@ http://purl.uniprot.org/uniprot/Q2USE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/510516:AO090026000163 ^@ http://purl.uniprot.org/uniprot/Q2UFL0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.|||Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.|||nucleolus http://togogenome.org/gene/510516:AO090023000834 ^@ http://purl.uniprot.org/uniprot/Q2UGI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Membrane http://togogenome.org/gene/510516:AO090001000230 ^@ http://purl.uniprot.org/uniprot/Q2UNU3 ^@ Similarity ^@ Belongs to the MSOX/MTOX family. http://togogenome.org/gene/510516:AO090138000058 ^@ http://purl.uniprot.org/uniprot/Q2U1X5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090102000565 ^@ http://purl.uniprot.org/uniprot/Q2UA32 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.|||Cell membrane|||The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses. http://togogenome.org/gene/510516:AO090026000455 ^@ http://purl.uniprot.org/uniprot/Q2UEW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SKN1/KRE6 family.|||Cell membrane|||Membrane http://togogenome.org/gene/510516:AO090001000172 ^@ http://purl.uniprot.org/uniprot/Q2UNZ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090026000284 ^@ http://purl.uniprot.org/uniprot/Q2UFA5 ^@ Similarity ^@ In the C-terminal section; belongs to the TrpB family.|||In the N-terminal section; belongs to the TrpA family. http://togogenome.org/gene/510516:AO090011000614 ^@ http://purl.uniprot.org/uniprot/Q2U026 ^@ Function ^@ Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway. http://togogenome.org/gene/510516:AO090010000756 ^@ http://purl.uniprot.org/uniprot/Q2TW00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.|||Membrane http://togogenome.org/gene/510516:AO090023000520 ^@ http://purl.uniprot.org/uniprot/Q2UHA7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NADPH--cytochrome P450 reductase family.|||Binds 1 FAD per monomer.|||Binds 1 FMN per monomer.|||Cell membrane|||Endoplasmic reticulum membrane|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.|||In the N-terminal section; belongs to the flavodoxin family.|||Mitochondrion outer membrane|||This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. http://togogenome.org/gene/510516:AO090038000430 ^@ http://purl.uniprot.org/uniprot/Q2U2J6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).|||Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.|||Nucleus|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/510516:AO090026000027 ^@ http://purl.uniprot.org/uniprot/Q2UFY8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090003000574 ^@ http://purl.uniprot.org/uniprot/Q2UL26 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/510516:AO090011000165 ^@ http://purl.uniprot.org/uniprot/Q2U154 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000451 ^@ http://purl.uniprot.org/uniprot/Q2USF0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. http://togogenome.org/gene/510516:AO090701000164 ^@ http://purl.uniprot.org/uniprot/Q2U957 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YIF1 family.|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Has a role in transport between endoplasmic reticulum and Golgi.|||Membrane http://togogenome.org/gene/510516:AO090001000713 ^@ http://purl.uniprot.org/uniprot/Q2UML2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090005001122 ^@ http://purl.uniprot.org/uniprot/Q2UQS4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Homodimer. http://togogenome.org/gene/510516:AO090012000420 ^@ http://purl.uniprot.org/uniprot/Q2UCW5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/510516:AO090038000575 ^@ http://purl.uniprot.org/uniprot/Q2U273 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/510516:AO090020000280 ^@ http://purl.uniprot.org/uniprot/Q2U4M5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090011000499 ^@ http://purl.uniprot.org/uniprot/Q2U0C2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prefoldin subunit alpha family.|||Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/510516:AO090020000555 ^@ http://purl.uniprot.org/uniprot/Q2U3Z6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090023000061 ^@ http://purl.uniprot.org/uniprot/Q2UIG8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090102000579 ^@ http://purl.uniprot.org/uniprot/Q2UA18 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SFH5 family.|||Cytoplasm|||Endoplasmic reticulum membrane|||Microsome membrane|||Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane. Heme-binding protein that may play a role in organic oxidant-induced stress responses. http://togogenome.org/gene/510516:AO090010000054 ^@ http://purl.uniprot.org/uniprot/Q2TXQ2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090120000317 ^@ http://purl.uniprot.org/uniprot/Q2U6A6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090701000364 ^@ http://purl.uniprot.org/uniprot/Q2U8M9 ^@ Similarity|||Subunit ^@ Belongs to the TPP enzyme family.|||Homotetramer. http://togogenome.org/gene/510516:AO090003000513 ^@ http://purl.uniprot.org/uniprot/Q2UL82 ^@ Similarity ^@ Belongs to the acetyltransferase family. MAK3 subfamily. http://togogenome.org/gene/510516:AO090026000503 ^@ http://purl.uniprot.org/uniprot/Q2UES4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RRP8 family.|||S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2.|||nucleolus http://togogenome.org/gene/510516:AO090012000216 ^@ http://purl.uniprot.org/uniprot/Q2UDD5 ^@ Similarity ^@ Belongs to the DCC1 family. http://togogenome.org/gene/510516:AO090011000364 ^@ http://purl.uniprot.org/uniprot/Q2U0N6 ^@ Similarity ^@ Belongs to the polysaccharide monooxygenase AA13 family. http://togogenome.org/gene/510516:AO090005000638 ^@ http://purl.uniprot.org/uniprot/Q2URY7 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/510516:AO090701000082 ^@ http://purl.uniprot.org/uniprot/Q2U9C6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LOC1 family.|||Component of the 66S pre-ribosomal particle.|||Required for efficient assembly and nuclear export of the 60S ribosomal subunit.|||nucleolus http://togogenome.org/gene/510516:AO090020000020 ^@ http://purl.uniprot.org/uniprot/Q2U597 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NRAP family.|||nucleolus http://togogenome.org/gene/510516:AO090005000883 ^@ http://purl.uniprot.org/uniprot/Q2URC5 ^@ Similarity ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/510516:AO090001000445 ^@ http://purl.uniprot.org/uniprot/Q2UNA2 ^@ Function|||Induction|||Similarity ^@ Functions as a fatty acid monooxygenase. Also displays a NADPH-dependent reductase activity in the C-terminal domain, which allows electron transfer from NADPH to the heme iron of the cytochrome P450 N-terminal domain.|||In the N-terminal section; belongs to the cytochrome P450 family.|||Induced by nitrogen limitation. http://togogenome.org/gene/510516:AO090166000103 ^@ http://purl.uniprot.org/uniprot/Q2U9L4 ^@ Similarity ^@ Belongs to the flavin monoamine oxidase family. http://togogenome.org/gene/510516:AO090023000054 ^@ http://purl.uniprot.org/uniprot/Q2UIH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090005000735 ^@ http://purl.uniprot.org/uniprot/Q2URQ0 ^@ Similarity ^@ Belongs to the putative lipase ROG1 family. http://togogenome.org/gene/510516:AO090020000071 ^@ http://purl.uniprot.org/uniprot/Q2U551 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family. http://togogenome.org/gene/510516:AO090005000355 ^@ http://purl.uniprot.org/uniprot/Q2USN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the transient receptor potential (TRP) ion channel family.|||Membrane http://togogenome.org/gene/510516:AO090102000231 ^@ http://purl.uniprot.org/uniprot/Q2UAU5 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/510516:AO090023000523 ^@ http://purl.uniprot.org/uniprot/Q2UHA4 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/510516:AO090701000296 ^@ http://purl.uniprot.org/uniprot/Q2U8T8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090038000112 ^@ http://purl.uniprot.org/uniprot/Q2U3B1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/510516:AO090011000791 ^@ http://purl.uniprot.org/uniprot/Q2TZM9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.|||Cytoplasm|||Monomer.|||Nucleus|||S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12. http://togogenome.org/gene/510516:AO090012000486 ^@ http://purl.uniprot.org/uniprot/Q2UCQ9 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase beta' chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/510516:AO090701000597 ^@ http://purl.uniprot.org/uniprot/Q2U827 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/510516:AO090020000027 ^@ http://purl.uniprot.org/uniprot/Q2U591 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. http://togogenome.org/gene/510516:AO090005001464 ^@ http://purl.uniprot.org/uniprot/Q2UPY0 ^@ Similarity ^@ Belongs to the FAH family. http://togogenome.org/gene/510516:AO090701000275 ^@ http://purl.uniprot.org/uniprot/Q2U8V8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090009000682 ^@ http://purl.uniprot.org/uniprot/Q2UTL6 ^@ Similarity ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily. http://togogenome.org/gene/510516:AO090012000249 ^@ http://purl.uniprot.org/uniprot/Q2UDA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TUBGCP family.|||microtubule organizing center http://togogenome.org/gene/510516:AO090011000835 ^@ http://purl.uniprot.org/uniprot/Q2TZI9 ^@ Similarity ^@ Belongs to the isochorismatase family. http://togogenome.org/gene/510516:AO090001000016 ^@ http://purl.uniprot.org/uniprot/Q2UPD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.|||Membrane http://togogenome.org/gene/510516:AO090038000291 ^@ http://purl.uniprot.org/uniprot/Q2U2W6 ^@ Similarity ^@ Belongs to the SAS10 family. http://togogenome.org/gene/510516:AO090009000030 ^@ http://purl.uniprot.org/uniprot/Q2UV63 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000595 ^@ http://purl.uniprot.org/uniprot/Q2US27 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CSN4 family.|||Nucleus http://togogenome.org/gene/510516:AO090003001186 ^@ http://purl.uniprot.org/uniprot/Q2UJJ4 ^@ Disruption Phenotype|||Function|||Subcellular Location Annotation ^@ Leads to longer aerial hyphae and to decreased conidia production (PubMed:30790620). Decreases transcriptional levels of the central development pathway genes brlA, abaA, and wetA during conidiation (PubMed:30790620). Leads to increased expression of kojR and kojA and a subsequent 6-fold increase of kojic acid production (PubMed:30790620).|||Nucleus|||Transcription factor that regulates conidiation as well as kojic acid production, likely by negatively controlling kojR and kojA expression. http://togogenome.org/gene/510516:AO090003000469 ^@ http://purl.uniprot.org/uniprot/Q2ULB9 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/510516:AO090011000034 ^@ http://purl.uniprot.org/uniprot/Q2U1G9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090026000586 ^@ http://purl.uniprot.org/uniprot/Q2UEK1 ^@ Similarity ^@ Belongs to the PAL/histidase family. http://togogenome.org/gene/510516:AO090005001224 ^@ http://purl.uniprot.org/uniprot/Q2UQJ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SDA1 family.|||Required for 60S pre-ribosomal subunits export to the cytoplasm.|||nucleolus http://togogenome.org/gene/510516:AO090026000705 ^@ http://purl.uniprot.org/uniprot/Q2UE99 ^@ Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. http://togogenome.org/gene/510516:AO090020000015 ^@ http://purl.uniprot.org/uniprot/Q2U5A0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20A family.|||Binds 2 manganese ions per subunit.|||Secreted http://togogenome.org/gene/510516:AO090012000721 ^@ http://purl.uniprot.org/uniprot/Q2UC65 ^@ Similarity ^@ Belongs to the palmitoyl-protein thioesterase family. http://togogenome.org/gene/510516:AO090701000017 ^@ http://purl.uniprot.org/uniprot/Q2U9I5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090701000110 ^@ http://purl.uniprot.org/uniprot/Q2U9A3 ^@ Similarity ^@ Belongs to the MIT1/WOR1 family. http://togogenome.org/gene/510516:AO090011000235 ^@ http://purl.uniprot.org/uniprot/Q2U0Z5 ^@ Cofactor|||Subcellular Location Annotation ^@ Binds 1 Ca(2+) ion per subunit.|||extracellular space http://togogenome.org/gene/510516:AO090005000379 ^@ http://purl.uniprot.org/uniprot/Q2USL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/510516:AO090020000404 ^@ http://purl.uniprot.org/uniprot/Q2U4C1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pectinesterase family.|||Involved in maceration and soft-rotting of plant tissue.|||Secreted http://togogenome.org/gene/510516:AO090005001176 ^@ http://purl.uniprot.org/uniprot/Q2UQN1 ^@ Similarity ^@ Belongs to the CCDC124 family. http://togogenome.org/gene/510516:AO090005001234 ^@ http://purl.uniprot.org/uniprot/Q2UQI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family.|||Mitochondrion membrane http://togogenome.org/gene/510516:AO090138000046 ^@ http://purl.uniprot.org/uniprot/Q2U1Y6 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/510516:AO090005001362 ^@ http://purl.uniprot.org/uniprot/Q2UQ76 ^@ Similarity ^@ Belongs to the TMA16 family. http://togogenome.org/gene/510516:AO090011000868 ^@ http://purl.uniprot.org/uniprot/O13416 ^@ Similarity ^@ Belongs to the OMP decarboxylase family. http://togogenome.org/gene/510516:AO090005001614 ^@ http://purl.uniprot.org/uniprot/Q2UPJ7 ^@ Similarity ^@ Belongs to the PITHD1 family. http://togogenome.org/gene/510516:AO090005001363 ^@ http://purl.uniprot.org/uniprot/Q2UQ75 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.|||Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.|||Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.|||Nucleus http://togogenome.org/gene/510516:AO090001000615 ^@ http://purl.uniprot.org/uniprot/Q2UMV0 ^@ Similarity ^@ Belongs to the AATF family. http://togogenome.org/gene/510516:AO090020000695 ^@ http://purl.uniprot.org/uniprot/Q2U3M7 ^@ Similarity ^@ Belongs to the amino acid/polyamine transporter 2 family. http://togogenome.org/gene/510516:AO090701000639 ^@ http://purl.uniprot.org/uniprot/Q2U7Z2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/510516:AO090003001316 ^@ http://purl.uniprot.org/uniprot/Q2UJ88 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Nudix hydrolase family. CPSF5 subfamily.|||Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.|||Cytoplasm|||Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.|||Nucleus http://togogenome.org/gene/510516:AO090011000948 ^@ http://purl.uniprot.org/uniprot/Q2TZ93 ^@ Similarity ^@ Belongs to the sorting nexin family. http://togogenome.org/gene/510516:AO090038000412 ^@ http://purl.uniprot.org/uniprot/Q2U2L3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRP31 family.|||Nucleus http://togogenome.org/gene/510516:AO090701000892 ^@ http://purl.uniprot.org/uniprot/Q2U7C6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090005001057 ^@ http://purl.uniprot.org/uniprot/Q2UQY0 ^@ Function|||Similarity ^@ Belongs to the Dus family. Dus3 subfamily.|||Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs (By similarity). Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation. http://togogenome.org/gene/510516:AO090124000010 ^@ http://purl.uniprot.org/uniprot/Q2U7A3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.|||Belongs to the actin family.|||cytoskeleton http://togogenome.org/gene/510516:AO090103000412 ^@ http://purl.uniprot.org/uniprot/Q2TY32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.|||Membrane http://togogenome.org/gene/510516:AO090011000812 ^@ http://purl.uniprot.org/uniprot/Q2TZL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase PH family.|||Cytoplasm http://togogenome.org/gene/510516:AO090138000120 ^@ http://purl.uniprot.org/uniprot/Q2U1S0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/510516:AO090026000520 ^@ http://purl.uniprot.org/uniprot/Q2UEQ8 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/510516:AO090005000530 ^@ http://purl.uniprot.org/uniprot/Q2US84 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/510516:AO090011000557 ^@ http://purl.uniprot.org/uniprot/Q2U075 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/510516:AO090005000442 ^@ http://purl.uniprot.org/uniprot/Q2USF9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GON7 family.|||Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.|||Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. GON7 likely plays a supporting role to the catalytic subunit KAE1 in the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.|||Nucleus http://togogenome.org/gene/510516:AO090001000359 ^@ http://purl.uniprot.org/uniprot/Q2UNH9 ^@ Similarity ^@ Belongs to the carotenoid oxygenase family. http://togogenome.org/gene/510516:AO090023000401 ^@ http://purl.uniprot.org/uniprot/Q2UHL4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 28 family.|||Involved in maceration and soft-rotting of plant tissue. Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall.|||Secreted http://togogenome.org/gene/510516:AO090701000801 ^@ http://purl.uniprot.org/uniprot/Q2U7K6 ^@ Similarity ^@ Belongs to the GILT family. http://togogenome.org/gene/510516:AO090012000119 ^@ http://purl.uniprot.org/uniprot/Q2UDM2 ^@ Similarity ^@ Belongs to the pyrroline-5-carboxylate reductase family. http://togogenome.org/gene/510516:AO090009000431 ^@ http://purl.uniprot.org/uniprot/Q2UU71 ^@ Similarity ^@ Belongs to the VPS25 family. http://togogenome.org/gene/510516:AO090003000442 ^@ http://purl.uniprot.org/uniprot/Q2ULE4 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/510516:AO090103000274 ^@ http://purl.uniprot.org/uniprot/Q2TYF1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000769 ^@ http://purl.uniprot.org/uniprot/Q2URM3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090102000513 ^@ http://purl.uniprot.org/uniprot/Q2UA74 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090026000704 ^@ http://purl.uniprot.org/uniprot/Q2UEA0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.|||Belongs to the NUF2 family.|||Component of the NDC80 complex, which consists of ndc80, nuf2, spc24 and spc25.|||Nucleus|||kinetochore http://togogenome.org/gene/510516:AO090012000199 ^@ http://purl.uniprot.org/uniprot/Q2UDE9 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/510516:AO090005000986 ^@ http://purl.uniprot.org/uniprot/Q2UR38 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 3 family.|||Secreted|||Xylan 1,4-beta-xylosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. http://togogenome.org/gene/510516:AO090120000503 ^@ http://purl.uniprot.org/uniprot/Q2U5U9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/510516:AO090009000505 ^@ http://purl.uniprot.org/uniprot/Q2UU14 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/510516:AO090003000923 ^@ http://purl.uniprot.org/uniprot/Q2UK76 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 81 family. http://togogenome.org/gene/510516:AO090011000732 ^@ http://purl.uniprot.org/uniprot/Q2TZT2 ^@ Similarity ^@ Belongs to the DAMOX/DASOX family. http://togogenome.org/gene/510516:AO090003000254 ^@ http://purl.uniprot.org/uniprot/Q2ULV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090011000824 ^@ http://purl.uniprot.org/uniprot/Q2TZJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NOSIP family.|||Nucleus http://togogenome.org/gene/510516:AO090012000995 ^@ http://purl.uniprot.org/uniprot/Q2UBH7 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/510516:AO090020000507 ^@ http://purl.uniprot.org/uniprot/Q2U437 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090102000624 ^@ http://purl.uniprot.org/uniprot/Q2U9X7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity).|||Nucleus http://togogenome.org/gene/510516:AO090012000838 ^@ http://purl.uniprot.org/uniprot/Q2UBW3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S26B family.|||Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).|||Component of the signal peptidase complex (SPC) composed of a catalytic subunit SEC11 and three accessory subunits SPC1, SPC2 and SPC3 (By similarity). The complex induces a local thinning of the ER membrane which is used to measure the length of the signal peptide (SP) h-region of protein substrates. This ensures the selectivity of the complex towards h-regions shorter than 18-20 amino acids (By similarity). SPC associates with the translocon complex (By similarity).|||Endoplasmic reticulum membrane|||The C-terminal short (CTS) helix is essential for catalytic activity. It may be accommodated as a transmembrane helix in the thinned membrane environment of the complex, similarly to the signal peptide in the complex substrates. http://togogenome.org/gene/510516:AO090003001022 ^@ http://purl.uniprot.org/uniprot/Q2UJY6 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/510516:AO090005000159 ^@ http://purl.uniprot.org/uniprot/Q2UT48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP11 family.|||Mitochondrion http://togogenome.org/gene/510516:AO090138000005 ^@ http://purl.uniprot.org/uniprot/Q2U219 ^@ Function ^@ Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway. http://togogenome.org/gene/510516:AO090701000872 ^@ http://purl.uniprot.org/uniprot/Q2U7E3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/510516:AO090023000840 ^@ http://purl.uniprot.org/uniprot/Q2UGH4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090026000751 ^@ http://purl.uniprot.org/uniprot/Q2UE60 ^@ Similarity ^@ Belongs to the U2 small nuclear ribonucleoprotein A family. http://togogenome.org/gene/510516:AO090012000847 ^@ http://purl.uniprot.org/uniprot/Q2UBV4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XPF family.|||Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).|||Interacts with EME1.|||Nucleus http://togogenome.org/gene/510516:AO090026000228 ^@ http://purl.uniprot.org/uniprot/Q2UFF5 ^@ Similarity ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family. http://togogenome.org/gene/510516:AO090012000948 ^@ http://purl.uniprot.org/uniprot/Q2UBL6 ^@ Function ^@ The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/510516:AO090023000259 ^@ http://purl.uniprot.org/uniprot/Q2UHY5 ^@ Similarity ^@ Belongs to the ERT1/acuK family. http://togogenome.org/gene/510516:AO090003000524 ^@ http://purl.uniprot.org/uniprot/Q2UL72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 28 family.|||Secreted http://togogenome.org/gene/510516:AO090023000801 ^@ http://purl.uniprot.org/uniprot/Q2UGL1 ^@ Function ^@ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.|||Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. http://togogenome.org/gene/510516:AO090701000189 ^@ http://purl.uniprot.org/uniprot/Q2U935 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RIX1/PELP1 family.|||Nucleus http://togogenome.org/gene/510516:AO090009000109 ^@ http://purl.uniprot.org/uniprot/Q2UUZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Membrane http://togogenome.org/gene/510516:AO090005001277 ^@ http://purl.uniprot.org/uniprot/Q2UQF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.|||Nucleus http://togogenome.org/gene/510516:AO090038000417 ^@ http://purl.uniprot.org/uniprot/Q2U2K8 ^@ Cofactor|||Similarity ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/510516:AO090010000340 ^@ http://purl.uniprot.org/uniprot/Q2TX03 ^@ Similarity ^@ Belongs to the flavin monoamine oxidase family. http://togogenome.org/gene/510516:AO090011000883 ^@ http://purl.uniprot.org/uniprot/Q2TZE5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TBCA family.|||Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.|||cytoskeleton http://togogenome.org/gene/510516:AO090124000009 ^@ http://purl.uniprot.org/uniprot/Q2U7A4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 28 family.|||Pectinolytic enzymes consist of four classes of enzymes: pectine lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Hydrolyzes alpha-D-galacturonopyranosyl-(1,2)-alpha-L-rhamnopyranosyl linkages in the backbone of the hairy regions of pectins (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090020000430 ^@ http://purl.uniprot.org/uniprot/Q2U497 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/510516:AO090103000346 ^@ http://purl.uniprot.org/uniprot/Q2TY88 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090701000704 ^@ http://purl.uniprot.org/uniprot/Q2U7T9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes medium subunit family.|||Membrane http://togogenome.org/gene/510516:AO090020000527 ^@ http://purl.uniprot.org/uniprot/Q2U420 ^@ Similarity ^@ Belongs to the tryptophan dimethylallyltransferase family. http://togogenome.org/gene/510516:AO090023000231 ^@ http://purl.uniprot.org/uniprot/Q2UI12 ^@ Similarity ^@ Belongs to the Tango6 family. http://togogenome.org/gene/510516:AO090005001133 ^@ http://purl.uniprot.org/uniprot/Q2UQR6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/510516:AO090003000277 ^@ http://purl.uniprot.org/uniprot/Q2ULT4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090011000909 ^@ http://purl.uniprot.org/uniprot/Q2TZC7 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090010000761 ^@ http://purl.uniprot.org/uniprot/Q2TVZ5 ^@ Similarity ^@ In the 2nd section; belongs to the type-I 3-dehydroquinase family.|||In the N-terminal section; belongs to the shikimate kinase family. http://togogenome.org/gene/510516:AO090003001228 ^@ http://purl.uniprot.org/uniprot/Q2UJG4 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/510516:AO090701000063 ^@ http://purl.uniprot.org/uniprot/Q2U9E2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FES1 family.|||Cytoplasm|||Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins (By similarity). http://togogenome.org/gene/510516:AO090026000550 ^@ http://purl.uniprot.org/uniprot/Q2UEN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||Membrane http://togogenome.org/gene/510516:AO090005001381 ^@ http://purl.uniprot.org/uniprot/Q2UQ59 ^@ Similarity ^@ Belongs to the proteasome subunit S14 family. http://togogenome.org/gene/510516:AO090701000462 ^@ http://purl.uniprot.org/uniprot/Q2U8E3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/510516:AO090005000757 ^@ http://purl.uniprot.org/uniprot/Q2URN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LCL3 family.|||Membrane|||Mitochondrion http://togogenome.org/gene/510516:AO090166000066 ^@ http://purl.uniprot.org/uniprot/Q2U9P8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090701000137 ^@ http://purl.uniprot.org/uniprot/Q2U980 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CLPTM1 family.|||Membrane http://togogenome.org/gene/510516:AO090023000933 ^@ http://purl.uniprot.org/uniprot/Q2UG92 ^@ Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family. http://togogenome.org/gene/510516:AO090010000659 ^@ http://purl.uniprot.org/uniprot/Q2TW88 ^@ Similarity ^@ Belongs to the FAH family. http://togogenome.org/gene/510516:AO090001000419 ^@ http://purl.uniprot.org/uniprot/Q2UNC6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090026000297 ^@ http://purl.uniprot.org/uniprot/Q2UF93 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 21 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/510516:AO090003000149 ^@ http://purl.uniprot.org/uniprot/Q2UM42 ^@ Function|||Similarity|||Subunit ^@ Belongs to the WD repeat creC family.|||Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Required to prevent the proteolysis of the CreB deubiquitinating enzyme in the absence of carbon catabolite repression. CreB deubiquitinating enzyme stabilized in a complex with the CreC leads to the expression of genes such as those in the proline and quinate pathways (By similarity).|||Interacts with creB. http://togogenome.org/gene/510516:AO090012000169 ^@ http://purl.uniprot.org/uniprot/Q2UDH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/510516:AO090003001552 ^@ http://purl.uniprot.org/uniprot/Q2UIM9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090120000425 ^@ http://purl.uniprot.org/uniprot/Q2U610 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.|||cytoskeleton http://togogenome.org/gene/510516:AO090701000158 ^@ http://purl.uniprot.org/uniprot/Q2U962 ^@ Function|||Similarity ^@ Belongs to the catalase family.|||Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.|||Serves to protect cells from the toxic effects of hydrogen peroxide. http://togogenome.org/gene/510516:AO090020000697 ^@ http://purl.uniprot.org/uniprot/Q2U3M5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 75 family.|||Chitosanase catalyzing the endo-type cleavage of chitosan, the deacylated form of chitin. Chitosanase may be crucial in the degradation of the deacetylated portion of chitin in the fungal cell wall. Chitoolisaccharides produced by the hydrolysis of partially N-acetylated chitosan are known to have many biological activities, including antibacterial activity, immune-enhancing effects, and elicitor activity.|||Secreted http://togogenome.org/gene/510516:AO090001000471 ^@ http://purl.uniprot.org/uniprot/Q2UN80 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm|||Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.|||Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. http://togogenome.org/gene/510516:AO090023000546 ^@ http://purl.uniprot.org/uniprot/Q2UH85 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/510516:AO090010000216 ^@ http://purl.uniprot.org/uniprot/Q2TXB0 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/510516:AO090001000735 ^@ http://purl.uniprot.org/uniprot/Q2UMJ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 14 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/510516:AO090005000347 ^@ http://purl.uniprot.org/uniprot/Q2USP5 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/510516:AO090012000845 ^@ http://purl.uniprot.org/uniprot/Q2UBV6 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. http://togogenome.org/gene/510516:AO090701000533 ^@ http://purl.uniprot.org/uniprot/Q2U884 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005001119 ^@ http://purl.uniprot.org/uniprot/Q2UQS7 ^@ Similarity ^@ Belongs to the FAX family. http://togogenome.org/gene/510516:AO090011000339 ^@ http://purl.uniprot.org/uniprot/Q2U0R0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SNF8 family.|||Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.|||Component of the endosomal sorting complex required for transport II (ESCRT-II). http://togogenome.org/gene/510516:AO090012000259 ^@ http://purl.uniprot.org/uniprot/Q2UDA0 ^@ Similarity ^@ Belongs to the hexokinase family. http://togogenome.org/gene/510516:AO090120000343 ^@ http://purl.uniprot.org/uniprot/Q2U682 ^@ Similarity ^@ Belongs to the XPG/RAD2 endonuclease family. http://togogenome.org/gene/510516:AO090003000211 ^@ http://purl.uniprot.org/uniprot/Q2ULZ2 ^@ Similarity ^@ Belongs to the FAH family. http://togogenome.org/gene/510516:AO090113000080 ^@ http://purl.uniprot.org/uniprot/Q2U5M9 ^@ Similarity ^@ Belongs to the p23/wos2 family. http://togogenome.org/gene/510516:AO090001000617 ^@ http://purl.uniprot.org/uniprot/Q2UMU8 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/510516:AO090120000170 ^@ http://purl.uniprot.org/uniprot/Q2U6N0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090012000254 ^@ http://purl.uniprot.org/uniprot/Q2UDA3 ^@ Similarity ^@ Belongs to the GILT family. http://togogenome.org/gene/510516:AO090009000480 ^@ http://purl.uniprot.org/uniprot/Q2UU31 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.|||Endoplasmic reticulum membrane|||Membrane|||Sterol O-acyltransferase that catalyzes the formation of stery esters. http://togogenome.org/gene/510516:AO090023000452 ^@ http://purl.uniprot.org/uniprot/Q2UHG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090005000100 ^@ http://purl.uniprot.org/uniprot/Q2UTA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TIM16/PAM16 family.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090120000318 ^@ http://purl.uniprot.org/uniprot/Q2U6A5 ^@ Similarity ^@ Belongs to the EIF1AD family. http://togogenome.org/gene/510516:AO090003001013 ^@ http://purl.uniprot.org/uniprot/Q2UJZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/510516:AO090005000300 ^@ http://purl.uniprot.org/uniprot/Q2UST6 ^@ Function|||Similarity ^@ Belongs to the PanB family.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate. http://togogenome.org/gene/510516:AO090012000998 ^@ http://purl.uniprot.org/uniprot/Q2UBH4 ^@ Similarity|||Subunit ^@ Belongs to the aerobic coproporphyrinogen-III oxidase family.|||Homodimer. http://togogenome.org/gene/510516:AO090012000901 ^@ http://purl.uniprot.org/uniprot/Q2UBR1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane|||Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. http://togogenome.org/gene/510516:AO090020000596 ^@ http://purl.uniprot.org/uniprot/Q2U3V9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome b560 family.|||Membrane http://togogenome.org/gene/510516:AO090206000030 ^@ http://purl.uniprot.org/uniprot/Q2PIW9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c-type heme lyase family.|||Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090005001632 ^@ http://purl.uniprot.org/uniprot/Q2UPI1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S10 family.|||Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).|||trans-Golgi network membrane http://togogenome.org/gene/510516:AO090012000203 ^@ http://purl.uniprot.org/uniprot/Q2UDE6 ^@ Similarity ^@ Belongs to the RNase PH family. http://togogenome.org/gene/510516:AO090003000782 ^@ http://purl.uniprot.org/uniprot/Q2UKJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090001000385 ^@ http://purl.uniprot.org/uniprot/Q2UNF7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003000615 ^@ http://purl.uniprot.org/uniprot/Q2UKY8 ^@ Function|||Similarity ^@ Belongs to the ARPC5 family.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. http://togogenome.org/gene/510516:AO090701000039 ^@ http://purl.uniprot.org/uniprot/Q2U9G5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003001205 ^@ http://purl.uniprot.org/uniprot/Q2UJI0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP72 family.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).|||Cytoplasm http://togogenome.org/gene/510516:AO090020000639 ^@ http://purl.uniprot.org/uniprot/Q2U3S4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090005000976 ^@ http://purl.uniprot.org/uniprot/Q2UR45 ^@ Similarity ^@ Belongs to the PRP18 family. http://togogenome.org/gene/510516:AO090103000213 ^@ http://purl.uniprot.org/uniprot/Q2TYK1 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/510516:AO090701000053 ^@ http://purl.uniprot.org/uniprot/Q2U9F2 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/510516:AO090011000659 ^@ http://purl.uniprot.org/uniprot/Q9HGZ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GPI family.|||Homodimer.|||In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.|||cytosol http://togogenome.org/gene/510516:AO090026000775 ^@ http://purl.uniprot.org/uniprot/Q2UE36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090001000657 ^@ http://purl.uniprot.org/uniprot/Q2UMR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NADH dehydrogenase family.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090005000666 ^@ http://purl.uniprot.org/uniprot/Q2URW4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/510516:AO090012000297 ^@ http://purl.uniprot.org/uniprot/Q2UD67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CYSTM1 family.|||Membrane http://togogenome.org/gene/510516:AO090012000899 ^@ http://purl.uniprot.org/uniprot/Q2UBR3 ^@ Miscellaneous|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer.|||In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes. http://togogenome.org/gene/510516:AO090206000079 ^@ http://purl.uniprot.org/uniprot/Q2PIS8 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||Membrane|||Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer. http://togogenome.org/gene/510516:AO090103000025 ^@ http://purl.uniprot.org/uniprot/Q2TZ12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-93 family.|||Membrane http://togogenome.org/gene/510516:AO090005001317 ^@ http://purl.uniprot.org/uniprot/Q2UQB6 ^@ Similarity ^@ Belongs to the FMO family. http://togogenome.org/gene/510516:AO090020000289 ^@ http://purl.uniprot.org/uniprot/Q2U4L7 ^@ Activity Regulation|||Biotechnology|||Function|||Similarity|||Subcellular Location Annotation ^@ Activity is inhibited by about 80% in the presence of 18% sodium chloride.|||Belongs to the fungal glutaminase gtaA family.|||Glutaminase catalyzes the hydrolysis of glutamine to glutamic acid and plays a key role in nitrogen metabolism. Catalyzes the hydrolysis not only of L-glutamine but also of D-glutamine.|||In the fermentation of soy sauce, the traditional Japanese seasoning, glutaminase is one of the most important enzymes in flavor enhancement as it converts glutamine to glutamic acid.|||Secreted http://togogenome.org/gene/510516:AO090038000193 ^@ http://purl.uniprot.org/uniprot/Q2U347 ^@ Similarity ^@ Belongs to the MSOX/MTOX family. http://togogenome.org/gene/510516:AO090012000026 ^@ http://purl.uniprot.org/uniprot/Q2UDU4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090026000626 ^@ http://purl.uniprot.org/uniprot/Q2UEG6 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/510516:AO090038000167 ^@ http://purl.uniprot.org/uniprot/Q2U366 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090009000178 ^@ http://purl.uniprot.org/uniprot/Q2UUU1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycosyl hydrolase 47 family.|||Cytoplasmic vesicle lumen|||Involved in the maturation of Asn-linked oligosaccharides. Progressively trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).|||Monomer. http://togogenome.org/gene/510516:AO090120000142 ^@ http://purl.uniprot.org/uniprot/Q2U6Q1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRM44 family.|||Cytoplasm|||Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase. http://togogenome.org/gene/510516:AO090005000560 ^@ http://purl.uniprot.org/uniprot/Q2US58 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/510516:AO090010000230 ^@ http://purl.uniprot.org/uniprot/Q2TX97 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. http://togogenome.org/gene/510516:AO090701000349 ^@ http://purl.uniprot.org/uniprot/Q2U8P2 ^@ Similarity ^@ Belongs to the alpha-acetolactate decarboxylase family. http://togogenome.org/gene/510516:AO090003001128 ^@ http://purl.uniprot.org/uniprot/Q2UJP6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090701000263 ^@ http://purl.uniprot.org/uniprot/Q2U8W9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the VPS17 family.|||Component of the retromer complex.|||Plays a role in vesicular protein sorting. http://togogenome.org/gene/510516:AO090102000637 ^@ http://purl.uniprot.org/uniprot/Q2U9W6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/510516:AO090012000548 ^@ http://purl.uniprot.org/uniprot/Q2UCK6 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/510516:AO090206000125 ^@ http://purl.uniprot.org/uniprot/Q2PIP1 ^@ Similarity ^@ Belongs to the pyrroline-5-carboxylate reductase family. http://togogenome.org/gene/510516:AO090023000854 ^@ http://purl.uniprot.org/uniprot/Q2UGG1 ^@ Similarity ^@ Belongs to the acetolactate synthase small subunit family. http://togogenome.org/gene/510516:AO090120000449 ^@ http://purl.uniprot.org/uniprot/Q2U5Z0 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090701000360 ^@ http://purl.uniprot.org/uniprot/Q2U8N3 ^@ Similarity ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family. http://togogenome.org/gene/510516:AO090005001209 ^@ http://purl.uniprot.org/uniprot/Q2UQK6 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/510516:AO090003000592 ^@ http://purl.uniprot.org/uniprot/Q2UL09 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090120000354 ^@ http://purl.uniprot.org/uniprot/Q2U673 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/510516:AO090038000061 ^@ http://purl.uniprot.org/uniprot/Q00234 ^@ Activity Regulation|||Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Activated by acidifying treatment at pH 3.0.|||Belongs to the tyrosinase family.|||Binds 2 copper ions per subunit.|||Homotetramer.|||The N-terminus is blocked.|||This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. http://togogenome.org/gene/510516:AO090010000741 ^@ http://purl.uniprot.org/uniprot/Q2TW15 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. http://togogenome.org/gene/510516:AO090003001298 ^@ http://purl.uniprot.org/uniprot/Q2UJA4 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/510516:AO090001000529 ^@ http://purl.uniprot.org/uniprot/Q2UN27 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PTPA-type PPIase family.|||Cytoplasm|||Nucleus|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity). http://togogenome.org/gene/510516:AO090011000052 ^@ http://purl.uniprot.org/uniprot/Q2U1F3 ^@ Activity Regulation|||Cofactor|||Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M28 family. M28E subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Calcium, magnesium and manganese cations reduce peptidase activity to 20.3-51.3 percent. The metal ion chelating reagent EDTA almost completely inhibits activity. The protease inhibitor bacitracin and the aminopeptidase B inhibitor bestatin, as well as DTT and beta-mercaptoethanol act also as lap A inhibitorsD.|||Expressed at higher level at alkaline conditions. May be under the control of pacC, the transcription factor that regulates pH-conditional gene expression. Expression is very low under normal condition, salt condition and heat-stress condition.|||Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.|||Monomer.|||Secreted http://togogenome.org/gene/510516:AO090003000683 ^@ http://purl.uniprot.org/uniprot/Q2UKT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TUBGCP family.|||microtubule organizing center http://togogenome.org/gene/510516:AO090011000095 ^@ http://purl.uniprot.org/uniprot/Q2U1B7 ^@ Similarity ^@ Belongs to the CWC26 family. http://togogenome.org/gene/510516:AO090012000110 ^@ http://purl.uniprot.org/uniprot/Q2UDM9 ^@ Similarity|||Subunit ^@ Belongs to the peptidase M28 family.|||Monomer. http://togogenome.org/gene/510516:AO090020000712 ^@ http://purl.uniprot.org/uniprot/Q2U3L1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 51 family. http://togogenome.org/gene/510516:AO090001000752 ^@ http://purl.uniprot.org/uniprot/Q2UMH5 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/510516:AO090308000003 ^@ http://purl.uniprot.org/uniprot/Q2UPG2 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/510516:AO090023000570 ^@ http://purl.uniprot.org/uniprot/Q2UH62 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/510516:AO090102000558 ^@ http://purl.uniprot.org/uniprot/Q2UA38 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/510516:AO090012000592 ^@ http://purl.uniprot.org/uniprot/Q2UCH0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the END3 family.|||Cell membrane|||Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).|||Component of the PAN1 actin cytoskeleton-regulatory complex.|||Endosome membrane|||actin patch http://togogenome.org/gene/510516:AO090023000405 ^@ http://purl.uniprot.org/uniprot/Q2UHL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090020000236 ^@ http://purl.uniprot.org/uniprot/Q2U4R2 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/510516:AO090701000504 ^@ http://purl.uniprot.org/uniprot/Q2U8A9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090701000472 ^@ http://purl.uniprot.org/uniprot/Q2U8D3 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/510516:AO090206000019 ^@ http://purl.uniprot.org/uniprot/Q2PIX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FGGY kinase family.|||Cytoplasm http://togogenome.org/gene/510516:AO090701000338 ^@ http://purl.uniprot.org/uniprot/Q2U8Q2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003001052 ^@ http://purl.uniprot.org/uniprot/Q2UJW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TFB1 family.|||Nucleus http://togogenome.org/gene/510516:AO090009000065 ^@ http://purl.uniprot.org/uniprot/Q2UV34 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/510516:AO090012000012 ^@ http://purl.uniprot.org/uniprot/Q2UDV6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090020000279 ^@ http://purl.uniprot.org/uniprot/Q2U4M6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Membrane http://togogenome.org/gene/510516:AO090120000042 ^@ http://purl.uniprot.org/uniprot/Q2U6Y6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090001000344 ^@ http://purl.uniprot.org/uniprot/Q2UNJ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CHS7 family.|||Chaperone required for the export of the chitin synthase chs3 from the endoplasmic reticulum.|||Endoplasmic reticulum membrane|||Interacts with chs3. http://togogenome.org/gene/510516:AO090026000537 ^@ http://purl.uniprot.org/uniprot/Q2UEP6 ^@ Similarity ^@ Belongs to the Rab GDI family. http://togogenome.org/gene/510516:AO090005001305 ^@ http://purl.uniprot.org/uniprot/Q2UQC6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit K family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/510516:AO090038000415 ^@ http://purl.uniprot.org/uniprot/Q2U2L0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the transient receptor potential (TRP) ion channel family.|||Membrane http://togogenome.org/gene/510516:AO090005000297 ^@ http://purl.uniprot.org/uniprot/Q2UST9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM86 family.|||Membrane http://togogenome.org/gene/510516:AO090026000094 ^@ http://purl.uniprot.org/uniprot/Q2UFS5 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090011000578 ^@ http://purl.uniprot.org/uniprot/Q2U057 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA5 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090003001423 ^@ http://purl.uniprot.org/uniprot/Q2UIY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/510516:AO090005000085 ^@ http://purl.uniprot.org/uniprot/Q2UTB4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000354 ^@ http://purl.uniprot.org/uniprot/Q2USN8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090023000123 ^@ http://purl.uniprot.org/uniprot/Q2UIB4 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/510516:AO090001000308 ^@ http://purl.uniprot.org/uniprot/Q2UNM2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090001000726 ^@ http://purl.uniprot.org/uniprot/Q2UMJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the transient receptor potential (TRP) ion channel family.|||Membrane http://togogenome.org/gene/510516:AO090103000204 ^@ http://purl.uniprot.org/uniprot/Q2TYK9 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. NTM1 family. http://togogenome.org/gene/510516:AO090038000031 ^@ http://purl.uniprot.org/uniprot/Q2U3H7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090001000530 ^@ http://purl.uniprot.org/uniprot/Q2UN26 ^@ Similarity ^@ Belongs to the CWC16 family. http://togogenome.org/gene/510516:AO090103000002 ^@ http://purl.uniprot.org/uniprot/Q2TZ33 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cyclophilin-type PPIase family. PPIase H subfamily.|||Nucleus|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). http://togogenome.org/gene/510516:AO090026000229 ^@ http://purl.uniprot.org/uniprot/Q2UFF4 ^@ Similarity ^@ Belongs to the complex I 49 kDa subunit family. http://togogenome.org/gene/510516:AO090003000806 ^@ http://purl.uniprot.org/uniprot/Q2UKH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VPS53 family.|||Endosome membrane|||Membrane|||trans-Golgi network membrane http://togogenome.org/gene/510516:AO090009000195 ^@ http://purl.uniprot.org/uniprot/Q2UUS6 ^@ Function|||Similarity ^@ Belongs to the 3-oxoacid CoA-transferase family.|||Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. http://togogenome.org/gene/510516:AO090005000545 ^@ http://purl.uniprot.org/uniprot/Q2US72 ^@ Function|||Similarity ^@ Belongs to the choline monooxygenase family.|||Catalyzes the first step of the osmoprotectant glycine betaine synthesis. http://togogenome.org/gene/510516:AO090005000904 ^@ http://purl.uniprot.org/uniprot/Q2URA5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PAM17 family.|||Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.|||Component of the PAM complex.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090010000750 ^@ http://purl.uniprot.org/uniprot/Q2TW06 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090009000600 ^@ http://purl.uniprot.org/uniprot/Q2UTT5 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/510516:AO090102000154 ^@ http://purl.uniprot.org/uniprot/Q2UB12 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RAD18 family.|||E3 RING-finger protein, member of the UBC2/RAD6 epistasis group. Associates to the E2 ubiquitin conjugating enzyme UBC2/RAD6 to form the UBC2-RAD18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA.|||Interacts with E2 UBC2, forming a complex with ubiquitin ligase activity.|||Nucleus http://togogenome.org/gene/510516:AO090138000062 ^@ http://purl.uniprot.org/uniprot/Q2U1X1 ^@ Similarity ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. http://togogenome.org/gene/510516:AO090026000815 ^@ http://purl.uniprot.org/uniprot/Q2UE00 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.|||Binds 1 Mg(2+) ion per monomer.|||Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Monomer.|||Nucleus http://togogenome.org/gene/510516:AO090020000032 ^@ http://purl.uniprot.org/uniprot/Q2U586 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL15 family. http://togogenome.org/gene/510516:AO090009000426 ^@ http://purl.uniprot.org/uniprot/Q2UU76 ^@ Similarity ^@ Belongs to the RNR ribonuclease family. http://togogenome.org/gene/510516:AO090026000264 ^@ http://purl.uniprot.org/uniprot/Q2UFC0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GrpE family.|||Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.|||Mitochondrion matrix http://togogenome.org/gene/510516:AO090001000561 ^@ http://purl.uniprot.org/uniprot/Q2UMZ5 ^@ Similarity ^@ Belongs to the eukaryotic NMN adenylyltransferase family. http://togogenome.org/gene/510516:AO090003000003 ^@ http://purl.uniprot.org/uniprot/Q2UMH2 ^@ Function ^@ Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins). http://togogenome.org/gene/510516:AO090038000249 ^@ http://purl.uniprot.org/uniprot/Q2U302 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL1 family. http://togogenome.org/gene/510516:AO090138000113 ^@ http://purl.uniprot.org/uniprot/Q2U1S7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090023000335 ^@ http://purl.uniprot.org/uniprot/Q2UHS1 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/510516:AO090001000111 ^@ http://purl.uniprot.org/uniprot/P87037 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 11 (cellulase G) family.|||Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.|||Secreted http://togogenome.org/gene/510516:AO090009000174 ^@ http://purl.uniprot.org/uniprot/Q2UUU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 48 family.|||Membrane http://togogenome.org/gene/510516:AO090113000122 ^@ http://purl.uniprot.org/uniprot/Q2U5J2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DASH complex DAD1 family.|||Nucleus|||kinetochore|||spindle http://togogenome.org/gene/510516:AO090701000381 ^@ http://purl.uniprot.org/uniprot/Q2U8L5 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/510516:AO090020000619 ^@ http://purl.uniprot.org/uniprot/Q2U3U1 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. http://togogenome.org/gene/510516:AO090011000821 ^@ http://purl.uniprot.org/uniprot/Q2TZK2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M14 family.|||Binds 1 zinc ion per subunit.|||Inactive carboxypeptidase that may play a role in cell wall organization and biogenesis.|||Lacks the conserved Glu residue in position 482 essential for carbopeptidase activity. The mature form lacks catalytic activity towards synthetic peptide substrates.|||Secreted|||Vacuole http://togogenome.org/gene/510516:AO090026000105 ^@ http://purl.uniprot.org/uniprot/Q2UFR5 ^@ Similarity ^@ Belongs to the NmrA-type oxidoreductase family. http://togogenome.org/gene/510516:AO090023000763 ^@ http://purl.uniprot.org/uniprot/Q2UGP7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ A monovalent cation.|||Belongs to the folylpolyglutamate synthase family.|||Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.|||Membrane|||Mitochondrion inner membrane|||Mitochondrion matrix http://togogenome.org/gene/510516:AO090102000502 ^@ http://purl.uniprot.org/uniprot/Q2UA84 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL4 family. http://togogenome.org/gene/510516:AO090023000858 ^@ http://purl.uniprot.org/uniprot/Q2UGF7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cut8/STS1 family.|||Binds the proteasome.|||Cytoplasm|||Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).|||Nucleus http://togogenome.org/gene/510516:AO090103000022 ^@ http://purl.uniprot.org/uniprot/Q2TZ14 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/510516:AO090003001549 ^@ http://purl.uniprot.org/uniprot/Q2UIN2 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. http://togogenome.org/gene/510516:AO090003000993 ^@ http://purl.uniprot.org/uniprot/Q2UK13 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/510516:AO090038000262 ^@ http://purl.uniprot.org/uniprot/Q2U2Z1 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/510516:AO090102000650 ^@ http://purl.uniprot.org/uniprot/Q2U9V6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ERD2 family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/510516:AO090003001546 ^@ http://purl.uniprot.org/uniprot/Q2UIN5 ^@ Similarity ^@ Belongs to the asaB hydroxylase/desaturase family. http://togogenome.org/gene/510516:AO090124000084 ^@ http://purl.uniprot.org/uniprot/Q2U733 ^@ Similarity|||Subunit ^@ Belongs to the fungal fatty acid synthetase subunit beta family.|||[Alpha(6)beta(6)] hexamers of two multifunctional subunits (alpha and beta). http://togogenome.org/gene/510516:AO090012000147 ^@ http://purl.uniprot.org/uniprot/Q2UDJ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 4 family.|||Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Degrades the rhamnogalacturonan I (RG-I) backbone of pectin (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090011000067 ^@ http://purl.uniprot.org/uniprot/Q2U1E0 ^@ Similarity ^@ Belongs to the CutC family. http://togogenome.org/gene/510516:AO090003001020 ^@ http://purl.uniprot.org/uniprot/Q2UJY8 ^@ Function|||Similarity ^@ Belongs to the NARF family.|||Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity). http://togogenome.org/gene/510516:AO090010000345 ^@ http://purl.uniprot.org/uniprot/Q2TWZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/510516:AO090102000573 ^@ http://purl.uniprot.org/uniprot/Q2UA24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/510516:AO090103000384 ^@ http://purl.uniprot.org/uniprot/Q2TY56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RBT5 family.|||Cell membrane|||Membrane|||cell wall http://togogenome.org/gene/510516:AO090005000217 ^@ http://purl.uniprot.org/uniprot/Q2UT06 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 27 family.|||Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.|||Secreted http://togogenome.org/gene/510516:AO090038000321 ^@ http://purl.uniprot.org/uniprot/Q2U2T9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/510516:AO090001000653 ^@ http://purl.uniprot.org/uniprot/Q2UMR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ESF1 family.|||nucleolus http://togogenome.org/gene/510516:AO090003000754 ^@ http://purl.uniprot.org/uniprot/Q2UKM0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ING family.|||Component of an histone acetyltransferase complex.|||Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.|||Nucleus|||The PHD-type zinc finger mediates the binding to H3K4me3. http://togogenome.org/gene/510516:AO090103000021 ^@ http://purl.uniprot.org/uniprot/Q2TZ15 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/510516:AO090010000315 ^@ http://purl.uniprot.org/uniprot/Q2TX25 ^@ Similarity ^@ Belongs to the NmrA-type oxidoreductase family. http://togogenome.org/gene/510516:AO090001000640 ^@ http://purl.uniprot.org/uniprot/Q2UMS6 ^@ Similarity ^@ Belongs to the PrpF family. http://togogenome.org/gene/510516:AO090010000764 ^@ http://purl.uniprot.org/uniprot/Q2TVZ2 ^@ Domain|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DENR family.|||Cytoplasm|||Interacts with the 40S ribosomal subunit.|||The SUI1 domain may be involved in RNA binding. http://togogenome.org/gene/510516:AO090023000467 ^@ http://purl.uniprot.org/uniprot/Q2UHF6 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/510516:AO090701000752 ^@ http://purl.uniprot.org/uniprot/Q2U7P9 ^@ Similarity ^@ Belongs to the amino acid/polyamine transporter 2 family. http://togogenome.org/gene/510516:AO090003001415 ^@ http://purl.uniprot.org/uniprot/Q2UIZ6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090011000535 ^@ http://purl.uniprot.org/uniprot/Q2U094 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RER1 family.|||Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.|||Membrane http://togogenome.org/gene/510516:AO090010000075 ^@ http://purl.uniprot.org/uniprot/Q2TXN5 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090012000544 ^@ http://purl.uniprot.org/uniprot/Q2UCL0 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/510516:AO090103000206 ^@ http://purl.uniprot.org/uniprot/Q2TYK7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090011000063 ^@ http://purl.uniprot.org/uniprot/Q2U1E4 ^@ Subunit ^@ Homotetramer. http://togogenome.org/gene/510516:AO090012000403 ^@ http://purl.uniprot.org/uniprot/Q2UCX9 ^@ Similarity ^@ Belongs to the glycosyltransferase 34 family. http://togogenome.org/gene/510516:AO090003000054 ^@ http://purl.uniprot.org/uniprot/Q2UMC5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit J family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/510516:AO090102000064 ^@ http://purl.uniprot.org/uniprot/Q2UB90 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090010000223 ^@ http://purl.uniprot.org/uniprot/Q2TXA3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS5 family. http://togogenome.org/gene/510516:AO090026000295 ^@ http://purl.uniprot.org/uniprot/Q2UF95 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.|||Belongs to the SPC24 family.|||Component of the NDC80 complex, which consists of ndc80, nuf2, spc24 and spc25.|||Nucleus|||kinetochore|||spindle pole body http://togogenome.org/gene/510516:AO090023000307 ^@ http://purl.uniprot.org/uniprot/Q2UHU5 ^@ Similarity ^@ Belongs to the MSOX/MTOX family. http://togogenome.org/gene/510516:AO090012000909 ^@ http://purl.uniprot.org/uniprot/Q2UBQ5 ^@ Similarity ^@ Belongs to the acetyltransferase family. ARD1 subfamily. http://togogenome.org/gene/510516:AO090020000064 ^@ http://purl.uniprot.org/uniprot/Q2U557 ^@ Similarity ^@ Belongs to the APC1 family. http://togogenome.org/gene/510516:AO090003000270 ^@ http://purl.uniprot.org/uniprot/Q2ULU0 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/510516:AO090701000013 ^@ http://purl.uniprot.org/uniprot/Q2U9I9 ^@ Similarity|||Subunit ^@ Belongs to the LDH/MDH superfamily. MDH type 1 family.|||Homodimer. http://togogenome.org/gene/510516:AO090003001365 ^@ http://purl.uniprot.org/uniprot/Q2UJ42 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090010000195 ^@ http://purl.uniprot.org/uniprot/Q2TXC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090011000352 ^@ http://purl.uniprot.org/uniprot/Q2U0P8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090113000014 ^@ http://purl.uniprot.org/uniprot/Q2U5T5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the beta-catenin family.|||Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.|||Vacuole membrane http://togogenome.org/gene/510516:AO090120000291 ^@ http://purl.uniprot.org/uniprot/Q2U6C8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/510516:AO090120000455 ^@ http://purl.uniprot.org/uniprot/Q2U5Y6 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/510516:AO090103000479 ^@ http://purl.uniprot.org/uniprot/Q2TXX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oligopeptide OPT transporter family.|||Membrane http://togogenome.org/gene/510516:AO090012000204 ^@ http://purl.uniprot.org/uniprot/Q2UDE5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.|||Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).|||Endoplasmic reticulum membrane http://togogenome.org/gene/510516:AO090001000221 ^@ http://purl.uniprot.org/uniprot/Q2UNV1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 61 family.|||Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM). The genes for catalytic modules and CBMs seem to have evolved separately and have been linked by gene fusion.|||Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds. Involved in the degradation of complex natural cellulosic substrates.|||Secreted http://togogenome.org/gene/510516:AO090023000257 ^@ http://purl.uniprot.org/uniprot/Q2UHY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oligopeptide OPT transporter family.|||Membrane http://togogenome.org/gene/510516:AO090038000543 ^@ http://purl.uniprot.org/uniprot/Q2U2A1 ^@ Similarity ^@ Belongs to the NRP synthetase family. http://togogenome.org/gene/510516:AO090023000758 ^@ http://purl.uniprot.org/uniprot/Q2UGQ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Mitochondrion http://togogenome.org/gene/510516:AO090103000109 ^@ http://purl.uniprot.org/uniprot/Q2TYU3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 76 family. http://togogenome.org/gene/510516:AO090005000308 ^@ http://purl.uniprot.org/uniprot/Q2USS8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/510516:AO090120000131 ^@ http://purl.uniprot.org/uniprot/Q2U6R0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL24 family. http://togogenome.org/gene/510516:AO090023000555 ^@ http://purl.uniprot.org/uniprot/Q2UH77 ^@ Similarity ^@ Belongs to the tpcK family. http://togogenome.org/gene/510516:AO090003001312 ^@ http://purl.uniprot.org/uniprot/Q2UJ92 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/510516:AO090005001357 ^@ http://purl.uniprot.org/uniprot/Q2UQ81 ^@ Function|||Similarity ^@ Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.|||Belongs to the adaptor complexes large subunit family. http://togogenome.org/gene/510516:AO090003000016 ^@ http://purl.uniprot.org/uniprot/Q2UMF9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase T1B family.|||Cytoplasm|||Non-catalytic component of the proteasome.|||Nucleus http://togogenome.org/gene/510516:AO090023000771 ^@ http://purl.uniprot.org/uniprot/Q2UGP0 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/510516:AO090003000559 ^@ http://purl.uniprot.org/uniprot/Q2UL40 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090102000032 ^@ http://purl.uniprot.org/uniprot/Q2UBB9 ^@ Similarity ^@ Belongs to the DAMOX/DASOX family. http://togogenome.org/gene/510516:AO090701000763 ^@ http://purl.uniprot.org/uniprot/Q2U7N9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHO1 family.|||Cell membrane|||Forms homooligomers.|||Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity. http://togogenome.org/gene/510516:AO090701000410 ^@ http://purl.uniprot.org/uniprot/Q2U8J3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090005001515 ^@ http://purl.uniprot.org/uniprot/Q2UPT7 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. FKBP2 subfamily.|||Endoplasmic reticulum|||Inhibited by both FK506 and rapamycin.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). http://togogenome.org/gene/510516:AO090026000252 ^@ http://purl.uniprot.org/uniprot/Q2UFD2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 28 family.|||Pectinolytic enzymes consist of four classes of enzymes: pectine lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Hydrolyzes alpha-D-galacturonopyranosyl-(1,2)-alpha-L-rhamnopyranosyl linkages in the backbone of the hairy regions of pectins (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090138000041 ^@ http://purl.uniprot.org/uniprot/Q2U1Z1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090103000010 ^@ http://purl.uniprot.org/uniprot/Q2TZ25 ^@ Similarity ^@ Belongs to the MIP18 family. http://togogenome.org/gene/510516:AO090038000233 ^@ http://purl.uniprot.org/uniprot/Q2U315 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090012001019 ^@ http://purl.uniprot.org/uniprot/Q2UBF6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CTL (choline transporter-like) family.|||Cell membrane|||Membrane|||Probably involved in transport through the plasma membrane. http://togogenome.org/gene/510516:AO090005001595 ^@ http://purl.uniprot.org/uniprot/Q2UPL5 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/510516:AO090120000167 ^@ http://purl.uniprot.org/uniprot/Q2U6N3 ^@ Similarity ^@ Belongs to the histidine acid phosphatase family. http://togogenome.org/gene/510516:AO090023000821 ^@ http://purl.uniprot.org/uniprot/Q2UGJ2 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/510516:AO090020000215 ^@ http://purl.uniprot.org/uniprot/Q2U4T1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090103000367 ^@ http://purl.uniprot.org/uniprot/Q2TY71 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090023000728 ^@ http://purl.uniprot.org/uniprot/Q2UGS6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERG4/ERG24 family.|||Membrane http://togogenome.org/gene/510516:AO090012000805 ^@ http://purl.uniprot.org/uniprot/Q2UBZ5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits. Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA. Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5.8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.|||Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.|||Component of pre-60S ribosomal complexes.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.|||nucleolus http://togogenome.org/gene/510516:AO090003000931 ^@ http://purl.uniprot.org/uniprot/Q2UK69 ^@ Miscellaneous|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer.|||In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes. http://togogenome.org/gene/510516:AO090020000159 ^@ http://purl.uniprot.org/uniprot/Q2U4X9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bifunctional enzyme that catalyzes the reactions from geranylgeranyl diphosphate to phytoene (phytoene synthase) and lycopene to beta-carotene via the intermediate gamma-carotene (lycopene cyclase).|||In the C-terminal section; belongs to the phytoene/squalene synthase family.|||In the N-terminal section; belongs to the lycopene beta-cyclase family.|||Membrane http://togogenome.org/gene/510516:AO090012000171 ^@ http://purl.uniprot.org/uniprot/Q2UDH4 ^@ Similarity ^@ Belongs to the globin family.|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. http://togogenome.org/gene/510516:AO090005000804 ^@ http://purl.uniprot.org/uniprot/Q2URJ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.|||Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.|||Interacts with the MHF histone-fold complex to form the FANCM-MHF complex.|||Nucleus http://togogenome.org/gene/510516:AO090001000669 ^@ http://purl.uniprot.org/uniprot/Q2UMQ0 ^@ Similarity ^@ Belongs to the HIT family. http://togogenome.org/gene/510516:AO090701000476 ^@ http://purl.uniprot.org/uniprot/Q2U8D0 ^@ Similarity ^@ Belongs to the CIA30 family. http://togogenome.org/gene/510516:AO090026000552 ^@ http://purl.uniprot.org/uniprot/Q2UEN3 ^@ Similarity ^@ Belongs to the PAF1 family. http://togogenome.org/gene/510516:AO090701000206 ^@ http://purl.uniprot.org/uniprot/Q2U920 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/510516:AO090005000209 ^@ http://purl.uniprot.org/uniprot/Q2UT13 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090120000104 ^@ http://purl.uniprot.org/uniprot/Q2U6T5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SGF11 family.|||Component of the 1.8 MDa SAGA transcription coactivator-HAT complex. SAGA is built of 5 distinct domains with specialized functions. Within the SAGA complex, SUS1, SGF11, SGF73 and UBP8 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with SGF73, SUS1 and UBP8.|||Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). Involved in transcriptional regulation of a subset of SAGA-regulated genes. Within the SAGA complex, participates in a subcomplex, that specifically deubiquitinates histones H2B.|||Nucleus http://togogenome.org/gene/510516:AO090023000964 ^@ http://purl.uniprot.org/uniprot/Q2UG62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERCC1/RAD10/SWI10 family.|||Nucleus http://togogenome.org/gene/510516:AO090701000132 ^@ http://purl.uniprot.org/uniprot/Q2U985 ^@ Similarity ^@ Belongs to the HEATR5 family. http://togogenome.org/gene/510516:AO090009000136 ^@ http://purl.uniprot.org/uniprot/Q2UUX3 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/510516:AO090003000012 ^@ http://purl.uniprot.org/uniprot/Q2UMG3 ^@ Function|||Similarity ^@ Belongs to the MDM31/MDM32 family.|||Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures. http://togogenome.org/gene/510516:AO090012000794 ^@ http://purl.uniprot.org/uniprot/Q2UC06 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/510516:AO090005001117 ^@ http://purl.uniprot.org/uniprot/Q2UQS9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sterol desaturase family. SCS7 subfamily.|||Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.|||Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/510516:AO090005000681 ^@ http://purl.uniprot.org/uniprot/Q2URV0 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/510516:AO090701000887 ^@ http://purl.uniprot.org/uniprot/Q2U7D0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 10 (cellulase F) family. http://togogenome.org/gene/510516:AO090102000274 ^@ http://purl.uniprot.org/uniprot/Q2UAR5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090001000557 ^@ http://purl.uniprot.org/uniprot/Q2UMZ9 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/510516:AO090026000714 ^@ http://purl.uniprot.org/uniprot/Q2UE92 ^@ Similarity ^@ Belongs to the DAMOX/DASOX family. http://togogenome.org/gene/510516:AO090038000274 ^@ http://purl.uniprot.org/uniprot/Q2U2Y0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endopolyphosphatase PPN1 family.|||Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.|||Membrane|||Vacuole membrane http://togogenome.org/gene/510516:AO090120000256 ^@ http://purl.uniprot.org/uniprot/Q2U6F6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase inhibitor family.|||Forms a one-to-one complex with ATPase to inhibit the enzyme activity completely.|||Mitochondrion http://togogenome.org/gene/510516:AO090120000008 ^@ http://purl.uniprot.org/uniprot/Q2U717 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M14 family.|||Inactive carboxypeptidase that may play a role in cell wall organization and biogenesis.|||Vacuole http://togogenome.org/gene/510516:AO090026000357 ^@ http://purl.uniprot.org/uniprot/Q2UF42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cerato-platanin family.|||Secreted http://togogenome.org/gene/510516:AO090009000270 ^@ http://purl.uniprot.org/uniprot/Q2UUL3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090001000499 ^@ http://purl.uniprot.org/uniprot/Q2UN55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the pym family.|||Cytoplasm http://togogenome.org/gene/510516:AO090010000579 ^@ http://purl.uniprot.org/uniprot/Q2TWF6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.|||Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/510516:AO090166000075 ^@ http://purl.uniprot.org/uniprot/Q2U9N9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20A family.|||Binds 2 Zn(2+) ions per subunit.|||Secreted http://togogenome.org/gene/510516:AO090001000390 ^@ http://purl.uniprot.org/uniprot/Q2UNF3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090206000056 ^@ http://purl.uniprot.org/uniprot/Q2PIU7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFB2 family.|||Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.|||Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.|||Nucleus http://togogenome.org/gene/510516:AO090120000294 ^@ http://purl.uniprot.org/uniprot/Q2U6C6 ^@ Similarity ^@ Belongs to the HMBS family. http://togogenome.org/gene/510516:AO090010000463 ^@ http://purl.uniprot.org/uniprot/Q2TWQ7 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/510516:AO090010000424 ^@ http://purl.uniprot.org/uniprot/Q2TWT8 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. http://togogenome.org/gene/510516:AO090005001332 ^@ http://purl.uniprot.org/uniprot/Q2UQA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/510516:AO090038000058 ^@ http://purl.uniprot.org/uniprot/Q2U3F7 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. http://togogenome.org/gene/510516:AO090010000314 ^@ http://purl.uniprot.org/uniprot/Q2TX26 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 7 (cellulase C) family.|||Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan. Involved in the degradation of complex natural cellulosic substrates.|||Secreted http://togogenome.org/gene/510516:AO090012000835 ^@ http://purl.uniprot.org/uniprot/Q2UBW6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CTL (choline transporter-like) family.|||Cell membrane|||Membrane|||Probably involved in transport through the plasma membrane. http://togogenome.org/gene/510516:AO090020000426 ^@ http://purl.uniprot.org/uniprot/Q2U4A1 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily. http://togogenome.org/gene/510516:AO090005000970 ^@ http://purl.uniprot.org/uniprot/Q2UR50 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/510516:AO090010000534 ^@ http://purl.uniprot.org/uniprot/Q2TWJ3 ^@ Similarity ^@ Belongs to the peptidase S10 family. http://togogenome.org/gene/510516:AO090113000061 ^@ http://purl.uniprot.org/uniprot/Q2U5P3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090120000255 ^@ http://purl.uniprot.org/uniprot/Q2U6F7 ^@ Similarity ^@ Belongs to the nucleoporin NSP1/NUP62 family. http://togogenome.org/gene/510516:AO090003000707 ^@ http://purl.uniprot.org/uniprot/Q2UKR2 ^@ Similarity ^@ Belongs to the MNN1/MNT family. http://togogenome.org/gene/510516:AO090120000129 ^@ http://purl.uniprot.org/uniprot/Q2U6R2 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/510516:AO090103000446 ^@ http://purl.uniprot.org/uniprot/Q2TXZ9 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. http://togogenome.org/gene/510516:AO090003000575 ^@ http://purl.uniprot.org/uniprot/Q2UL25 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090001000232 ^@ http://purl.uniprot.org/uniprot/Q2UNU1 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. http://togogenome.org/gene/510516:AO090120000364 ^@ http://purl.uniprot.org/uniprot/Q2U664 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GcvT family. CAF17 subfamily.|||Mitochondrion http://togogenome.org/gene/510516:AO090103000012 ^@ http://purl.uniprot.org/uniprot/Q2TZ23 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/510516:AO090011000290 ^@ http://purl.uniprot.org/uniprot/Q2U0V5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associated with the spliceosome.|||Belongs to the SLT11 family.|||Involved in pre-mRNA splicing. Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome. Binds to RNA.|||Nucleus http://togogenome.org/gene/510516:AO090003001390 ^@ http://purl.uniprot.org/uniprot/Q9HGZ1 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/510516:AO090026000542 ^@ http://purl.uniprot.org/uniprot/Q2UEP2 ^@ Similarity ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. http://togogenome.org/gene/510516:AO090005000739 ^@ http://purl.uniprot.org/uniprot/Q2URP6 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/510516:AO090012000157 ^@ http://purl.uniprot.org/uniprot/Q2UDI8 ^@ Similarity ^@ Belongs to the peptidase M28 family. M28B subfamily. http://togogenome.org/gene/510516:AO090124000088 ^@ http://purl.uniprot.org/uniprot/Q2U729 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/510516:AO090120000112 ^@ http://purl.uniprot.org/uniprot/Q2U6S7 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family. Prx5 subfamily.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/510516:AO090026000672 ^@ http://purl.uniprot.org/uniprot/Q2UEC7 ^@ Similarity ^@ Belongs to the actin family. ARP3 subfamily. http://togogenome.org/gene/510516:AO090026000526 ^@ http://purl.uniprot.org/uniprot/Q2UEQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/510516:AO090010000622 ^@ http://purl.uniprot.org/uniprot/Q2TWC1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 76 family. http://togogenome.org/gene/510516:AO090005000228 ^@ http://purl.uniprot.org/uniprot/Q2USZ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090011000230 ^@ http://purl.uniprot.org/uniprot/Q2U100 ^@ Function|||Similarity|||Subunit ^@ Belongs to the mannitol dehydrogenase family.|||Catalyzes the NAD(H)-dependent interconversion of D-fructose and D-mannitol in the mannitol metabolic pathway.|||Monomer. http://togogenome.org/gene/510516:AO090009000481 ^@ http://purl.uniprot.org/uniprot/Q2UU30 ^@ Similarity ^@ Belongs to the adaptor complexes large subunit family. http://togogenome.org/gene/510516:AO090701000087 ^@ http://purl.uniprot.org/uniprot/Q2U9C3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with 90S and pre-40S pre-ribosomal particles.|||Belongs to the RRP36 family.|||Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).|||nucleolus http://togogenome.org/gene/510516:AO090020000217 ^@ http://purl.uniprot.org/uniprot/Q2U4S9 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/510516:AO090011000441 ^@ http://purl.uniprot.org/uniprot/Q2U0H2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL22 family. http://togogenome.org/gene/510516:AO090026000547 ^@ http://purl.uniprot.org/uniprot/Q2UEN8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tyrosyl-DNA phosphodiesterase family.|||Nucleus http://togogenome.org/gene/510516:AO090009000264 ^@ http://purl.uniprot.org/uniprot/Q2UUL9 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily. http://togogenome.org/gene/510516:AO090005001572 ^@ http://purl.uniprot.org/uniprot/Q2UPN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cornichon family.|||Membrane http://togogenome.org/gene/510516:AO090120000396 ^@ http://purl.uniprot.org/uniprot/Q2U637 ^@ Function|||Similarity ^@ Belongs to the dihydroxyacetone kinase (DAK) family.|||Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde. http://togogenome.org/gene/510516:AO090026000785 ^@ http://purl.uniprot.org/uniprot/Q2UE26 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.|||Mediates the uptake of pyruvate into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090003000609 ^@ http://purl.uniprot.org/uniprot/Q2UKZ4 ^@ Similarity ^@ Belongs to the peptidase M28 family. M28B subfamily. http://togogenome.org/gene/510516:AO090120000135 ^@ http://purl.uniprot.org/uniprot/Q2U6Q7 ^@ Miscellaneous|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer.|||In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes. http://togogenome.org/gene/510516:AO090005001078 ^@ http://purl.uniprot.org/uniprot/Q2UQW1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/510516:AO090001000594 ^@ http://purl.uniprot.org/uniprot/Q2UMW5 ^@ Function|||Similarity ^@ Belongs to the PanB family.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate. http://togogenome.org/gene/510516:AO090005000575 ^@ http://purl.uniprot.org/uniprot/Q2US46 ^@ Similarity ^@ Belongs to the OPA3 family. http://togogenome.org/gene/510516:AO090020000690 ^@ http://purl.uniprot.org/uniprot/Q2U3N2 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. http://togogenome.org/gene/510516:AO090120000257 ^@ http://purl.uniprot.org/uniprot/Q2U6F5 ^@ Similarity ^@ Belongs to the 14-3-3 family. http://togogenome.org/gene/510516:AO090012001004 ^@ http://purl.uniprot.org/uniprot/Q2UBH0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family. AK2 subfamily.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Mitochondrion intermembrane space|||Monomer.|||cytosol http://togogenome.org/gene/510516:AO090120000157 ^@ http://purl.uniprot.org/uniprot/Q2U6P2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family. SMC5 subfamily.|||Nucleus http://togogenome.org/gene/510516:AO090005000842 ^@ http://purl.uniprot.org/uniprot/Q2URG1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.|||Cell membrane|||The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses. http://togogenome.org/gene/510516:AO090102000642 ^@ http://purl.uniprot.org/uniprot/Q2U9W2 ^@ Function|||Subcellular Location Annotation ^@ RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.|||nucleolus http://togogenome.org/gene/510516:AO090005000896 ^@ http://purl.uniprot.org/uniprot/Q2URB3 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/510516:AO090023000599 ^@ http://purl.uniprot.org/uniprot/Q2UH38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Membrane http://togogenome.org/gene/510516:AO090001000664 ^@ http://purl.uniprot.org/uniprot/Q2UMQ5 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Autoacetylation at Lys-318 is required for proper function.|||Belongs to the MYST (SAS/MOZ) family.|||Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z (By similarity). Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, and histone H2A to form H2AK4ac and H2AK7ac (By similarity). The NuA4 complex is involved in the DNA damage response and is required for chromosome segregation. The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) through homologous recombination (By similarity). Recruitment to promoters depends on H3K4me. Also acetylates non-histone proteins (By similarity). In addition to protein acetyltransferase, can use different acyl-CoA substrates, such as 2-hydroxyisobutanoyl-CoA (2-hydroxyisobutyryl-CoA) or (2E)-butenoyl-CoA (crotonyl-CoA), and is able to mediate protein 2-hydroxyisobutyrylation and crotonylation, respectively (By similarity).|||Chromosome|||Component of the NuA4 histone acetyltransferase complex.|||Nucleus|||The ESA1-RPD3 motif is common to ESA1 and RPD3 and is required for ESA1 histone acetyl-transferase (HAT) activity and RPD3 histone deacetylase (HDAC) activity. http://togogenome.org/gene/510516:AO090103000320 ^@ http://purl.uniprot.org/uniprot/Q2TYB1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Nuclear serine protease which mediates apoptosis.|||Nucleus http://togogenome.org/gene/510516:AO090005001072 ^@ http://purl.uniprot.org/uniprot/Q2UQW7 ^@ Similarity ^@ Belongs to the NOC2 family. http://togogenome.org/gene/510516:AO090011000534 ^@ http://purl.uniprot.org/uniprot/Q2U095 ^@ Similarity ^@ Belongs to the MGR2 family. http://togogenome.org/gene/510516:AO090026000741 ^@ http://purl.uniprot.org/uniprot/Q2UE69 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/510516:AO090102000056 ^@ http://purl.uniprot.org/uniprot/Q2UB98 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090023000714 ^@ http://purl.uniprot.org/uniprot/Q2UGU0 ^@ Function|||Similarity ^@ Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.|||Belongs to the proteasome subunit S1 family. http://togogenome.org/gene/510516:AO090011000785 ^@ http://purl.uniprot.org/uniprot/Q2TZN5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090005000494 ^@ http://purl.uniprot.org/uniprot/Q2USB5 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/510516:AO090005001582 ^@ http://purl.uniprot.org/uniprot/Q2UPM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGS family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/510516:AO090120000319 ^@ http://purl.uniprot.org/uniprot/Q2U6A4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.|||Belongs to the ALG3 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/510516:AO090701000241 ^@ http://purl.uniprot.org/uniprot/Q2U8Y8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003001238 ^@ http://purl.uniprot.org/uniprot/Q2UJF5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MDM34 family.|||Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of mmm1, mdm10, mdm12 and mdm34.|||Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm34 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10.|||Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.|||Mitochondrion outer membrane|||The SMP-LTD domain is a barrel-like domain that can bind various types of glycerophospholipids in its interior and mediate their transfer between two adjacent bilayers. http://togogenome.org/gene/510516:AO090003000133 ^@ http://purl.uniprot.org/uniprot/Q2UM55 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/510516:AO090012000503 ^@ http://purl.uniprot.org/uniprot/Q2UCP5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.|||Nucleus|||Possesses 5'->3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote termination of transcription by RNA polymerase II (By similarity). http://togogenome.org/gene/510516:AO090009000565 ^@ http://purl.uniprot.org/uniprot/Q2UTW4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090701000003 ^@ http://purl.uniprot.org/uniprot/Q2U9J8 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/510516:AO090026000004 ^@ http://purl.uniprot.org/uniprot/Q2UG10 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090011000537 ^@ http://purl.uniprot.org/uniprot/Q2U092 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/510516:AO090026000495 ^@ http://purl.uniprot.org/uniprot/Q2UET1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.|||Involved in the biogenesis of the 60S ribosomal subunit.|||nucleolus http://togogenome.org/gene/510516:AO090012000988 ^@ http://purl.uniprot.org/uniprot/Q2UBI1 ^@ Cofactor|||Similarity ^@ Belongs to the glutamate synthase family.|||Binds 1 [3Fe-4S] cluster. http://togogenome.org/gene/510516:AO090010000598 ^@ http://purl.uniprot.org/uniprot/Q2TWE0 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/510516:AO090102000602 ^@ http://purl.uniprot.org/uniprot/Q2U9Z7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NOB1 family.|||Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm.|||nucleolus http://togogenome.org/gene/510516:AO090005000018 ^@ http://purl.uniprot.org/uniprot/Q2UTH3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003000407 ^@ http://purl.uniprot.org/uniprot/Q2ULH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIM24 family.|||Mitochondrion http://togogenome.org/gene/510516:AO090020000194 ^@ http://purl.uniprot.org/uniprot/Q2U4V0 ^@ Similarity ^@ Belongs to the terpene cyclase/mutase family. http://togogenome.org/gene/510516:AO090701000073 ^@ http://purl.uniprot.org/uniprot/Q2U9D3 ^@ Similarity ^@ Belongs to the glycosyltransferase 32 family. http://togogenome.org/gene/510516:AO090102000039 ^@ http://purl.uniprot.org/uniprot/Q2UBB2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090011000268 ^@ http://purl.uniprot.org/uniprot/Q2U0X1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003001100 ^@ http://purl.uniprot.org/uniprot/Q2UJS0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PRM1 family.|||Cell membrane|||Involved in cell fusion during mating by stabilizing the plasma membrane fusion event. http://togogenome.org/gene/510516:AO090005000128 ^@ http://purl.uniprot.org/uniprot/Q2UT76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS29 family.|||Mitochondrion http://togogenome.org/gene/510516:AO090012000682 ^@ http://purl.uniprot.org/uniprot/Q2UC99 ^@ Similarity ^@ Belongs to the PhyH family. http://togogenome.org/gene/510516:AO090020000141 ^@ http://purl.uniprot.org/uniprot/Q2U4Z5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090003000111 ^@ http://purl.uniprot.org/uniprot/Q2UM74 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090001000701 ^@ http://purl.uniprot.org/uniprot/Q2UMM4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the flavokinase family.|||Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.|||Zinc or magnesium. http://togogenome.org/gene/510516:AO090003000263 ^@ http://purl.uniprot.org/uniprot/Q2ULU6 ^@ Activity Regulation|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase C19 family. PAN2 subfamily.|||Binds 2 metal cations per subunit in the catalytic exonuclease domain.|||Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein pab1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by xrn1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails.|||Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.|||Cytoplasm|||Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit pan3 to form the poly(A)-nuclease (PAN) deadenylation complex.|||Positively regulated by the regulatory subunit pan3.|||The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with pan3. http://togogenome.org/gene/510516:AO090038000551 ^@ http://purl.uniprot.org/uniprot/Q2U294 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/510516:AO090701000751 ^@ http://purl.uniprot.org/uniprot/Q2U7Q0 ^@ Function ^@ Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway. http://togogenome.org/gene/510516:AO090005001584 ^@ http://purl.uniprot.org/uniprot/Q2UPM5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090012000137 ^@ http://purl.uniprot.org/uniprot/Q2UDK5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090138000160 ^@ http://purl.uniprot.org/uniprot/Q2U1N5 ^@ Cofactor|||Function|||Induction|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M36 family.|||Binds 1 zinc ion per subunit.|||Expression is controlled by the prtT transcription factor.|||Secreted|||Secreted metalloproteinase that allows assimilation of proteinaceous substrates. http://togogenome.org/gene/510516:AO090038000466 ^@ http://purl.uniprot.org/uniprot/Q2U2G3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/510516:AO090001000192 ^@ http://purl.uniprot.org/uniprot/Q2UNX6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lunapark family.|||Endoplasmic reticulum membrane|||Plays a role in determining ER morphology.|||The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation. http://togogenome.org/gene/510516:AO090005000853 ^@ http://purl.uniprot.org/uniprot/Q2URF2 ^@ Similarity ^@ Belongs to the UFD1 family. http://togogenome.org/gene/510516:AO090012000830 ^@ http://purl.uniprot.org/uniprot/Q2UBX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family. BCS1 subfamily.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090026000521 ^@ http://purl.uniprot.org/uniprot/Q2UEQ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer. http://togogenome.org/gene/510516:AO090103000168 ^@ http://purl.uniprot.org/uniprot/Q2TYP2 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/510516:AO090012000252 ^@ http://purl.uniprot.org/uniprot/Q2UDA5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090011000744 ^@ http://purl.uniprot.org/uniprot/Q2TZS0 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/510516:AO090103000151 ^@ http://purl.uniprot.org/uniprot/Q2TYQ6 ^@ Similarity ^@ Belongs to the HMBS family. http://togogenome.org/gene/510516:AO090003000077 ^@ http://purl.uniprot.org/uniprot/Q2UMA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090003000925 ^@ http://purl.uniprot.org/uniprot/Q2UK74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL41 family.|||Mitochondrion http://togogenome.org/gene/510516:AO090001000376 ^@ http://purl.uniprot.org/uniprot/Q2UNG5 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/510516:AO090010000170 ^@ http://purl.uniprot.org/uniprot/Q2TXF1 ^@ Function|||Similarity ^@ Belongs to the citrate synthase family.|||Citrate synthase-like protein; part of the gene cluster that mediates the biosynthesis of oryzines, natural products with an unusual maleidride backbone (PubMed:30104550). The two subunits of the fungal fatty acid synthase oryfasA and oryfasB probably form octenoic acid (Probable). This fatty acid is most likely activated by the acyl-CoA ligase oryP to give octenyl-CoA before the citrate synthase-like protein oryE catalyzes condensation with oxaloacetate to form tricarboxylic acid (Probable). The next steps of the pathways are conjectural, but a favorite possible route has been proposed, beginning with decarboxylation and concomitant dehydration by the decarboxylase oryM, followed by tautomerization, which may lead to the production of a diene intermediate (Probable). Reduction of this diene intermediate could give the known metabolite piliformic acid (Probable). On the pathway to oryzine B and oryzine A, however, hydroxylation of the diene by the alpha-ketoglutarate-dependent dioxygenase oryG and lactonisation by the lactonohydrolases oryH or oryL could give oryzine B directly (Probable). Finally, enoyl reduction by the dehydrogenase oryD would then convert oryzine B into oryzine A (Probable). http://togogenome.org/gene/510516:AO090023000628 ^@ http://purl.uniprot.org/uniprot/Q2UH16 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/510516:AO090038000396 ^@ http://purl.uniprot.org/uniprot/Q2U2M6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||Membrane http://togogenome.org/gene/510516:AO090026000491 ^@ http://purl.uniprot.org/uniprot/Q2UET4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERG28 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/510516:AO090701000692 ^@ http://purl.uniprot.org/uniprot/Q2U7V0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. LDAH family.|||Lipid droplet http://togogenome.org/gene/510516:AO090038000349 ^@ http://purl.uniprot.org/uniprot/Q2U2R5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associated with the spliceosome.|||Belongs to the WD repeat PRL1/PRL2 family.|||Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.|||Nucleus http://togogenome.org/gene/510516:AO090120000460 ^@ http://purl.uniprot.org/uniprot/Q2U5Y2 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/510516:AO090003001081 ^@ http://purl.uniprot.org/uniprot/Q2UJT6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090023000047 ^@ http://purl.uniprot.org/uniprot/Q2UII1 ^@ Similarity ^@ Belongs to the tannase family. http://togogenome.org/gene/510516:AO090012000787 ^@ http://purl.uniprot.org/uniprot/Q2UC13 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/510516:AO090003001341 ^@ http://purl.uniprot.org/uniprot/Q2UJ64 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/510516:AO090138000091 ^@ http://purl.uniprot.org/uniprot/Q2U1U6 ^@ Similarity ^@ Belongs to the dermatan-sulfate isomerase family. http://togogenome.org/gene/510516:AO090026000023 ^@ http://purl.uniprot.org/uniprot/Q2UFZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the anthrone oxygenase family.|||Membrane http://togogenome.org/gene/510516:AO090701000753 ^@ http://purl.uniprot.org/uniprot/Q2U7P8 ^@ Similarity ^@ Belongs to the alpha-actinin family. http://togogenome.org/gene/510516:AO090009000485 ^@ http://purl.uniprot.org/uniprot/Q2UU26 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL13 family. http://togogenome.org/gene/510516:AO090038000621 ^@ http://purl.uniprot.org/uniprot/Q2U233 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/510516:AO090038000090 ^@ http://purl.uniprot.org/uniprot/Q2U3D0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090005001601 ^@ http://purl.uniprot.org/uniprot/Q2UPK9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL6 family. http://togogenome.org/gene/510516:AO090005001261 ^@ http://purl.uniprot.org/uniprot/Q2UQG3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.|||Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate-binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions.|||Heterodimer consisting of MSH2-MSH3 (MutS beta). Forms a ternary complex with MutL alpha (MLH1-PMS1).|||Nucleus http://togogenome.org/gene/510516:AO090001000337 ^@ http://purl.uniprot.org/uniprot/Q2UNJ7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||Mitochondrion|||The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/510516:AO090005001406 ^@ http://purl.uniprot.org/uniprot/Q2UQ34 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit I family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/510516:AO090003000295 ^@ http://purl.uniprot.org/uniprot/Q2ULR9 ^@ Subcellular Location Annotation|||Subunit ^@ Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. http://togogenome.org/gene/510516:AO090120000101 ^@ http://purl.uniprot.org/uniprot/Q2U6T8 ^@ Similarity ^@ Belongs to the RNase PH family. http://togogenome.org/gene/510516:AO090113000041 ^@ http://purl.uniprot.org/uniprot/Q2U5R2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090020000429 ^@ http://purl.uniprot.org/uniprot/Q2U498 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ISY1 family.|||Nucleus http://togogenome.org/gene/510516:AO090023000450 ^@ http://purl.uniprot.org/uniprot/Q2UHH0 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090701000424 ^@ http://purl.uniprot.org/uniprot/Q2U8I0 ^@ Similarity ^@ Belongs to the asaB hydroxylase/desaturase family. http://togogenome.org/gene/510516:AO090005001021 ^@ http://purl.uniprot.org/uniprot/Q2UR09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/510516:AO090103000444 ^@ http://purl.uniprot.org/uniprot/Q2TY01 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/510516:AO090011000167 ^@ http://purl.uniprot.org/uniprot/Q2U152 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ThrE exporter (TC 2.A.79) family.|||Membrane http://togogenome.org/gene/510516:AO090010000390 ^@ http://purl.uniprot.org/uniprot/Q2TWW2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090003000103 ^@ http://purl.uniprot.org/uniprot/Q2UM81 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/510516:AO090138000079 ^@ http://purl.uniprot.org/uniprot/Q2U1V8 ^@ Cofactor|||PTM|||Similarity ^@ Belongs to the copper/topaquinone oxidase family.|||Contains 1 topaquinone per subunit.|||Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. http://togogenome.org/gene/510516:AO090003001416 ^@ http://purl.uniprot.org/uniprot/Q2UIZ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090023000127 ^@ http://purl.uniprot.org/uniprot/Q2UIB0 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/510516:AO090020000179 ^@ http://purl.uniprot.org/uniprot/Q2U4W2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MoaE family. MOCS2B subfamily.|||Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.|||Cytoplasm|||Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits. http://togogenome.org/gene/510516:AO090701000214 ^@ http://purl.uniprot.org/uniprot/Q2U913 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Cytoplasm http://togogenome.org/gene/510516:AO090010000713 ^@ http://purl.uniprot.org/uniprot/Q2TW43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/510516:AO090005001528 ^@ http://purl.uniprot.org/uniprot/Q2UPS5 ^@ Caution|||Similarity ^@ Although strongly related to the peptide:N-glycanase enzyme, it lacks the conserved active site Cys in position 259, which is replaced by a Val residue suggesting that it has no activity.|||Belongs to the transglutaminase-like superfamily. PNGase family. http://togogenome.org/gene/510516:AO090023000372 ^@ http://purl.uniprot.org/uniprot/Q2UHN8 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/510516:AO090124000052 ^@ http://purl.uniprot.org/uniprot/Q2U764 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.|||Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.|||Membrane|||Vacuole membrane http://togogenome.org/gene/510516:AO090011000378 ^@ http://purl.uniprot.org/uniprot/Q2U0M6 ^@ Disruption Phenotype|||Function|||Induction|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.|||Cell membrane|||Expression is highly up-regulated in azole resistant strains and in the presence of miconazole.|||Leads to strong miconazole susceptibility.|||Pleiotropic ABC efflux transporter involved in the basal level of azole susceptibility (PubMed:30011258). Confers resistance to miconazole and clotrimazole (PubMed:30011258). http://togogenome.org/gene/510516:AO090012000584 ^@ http://purl.uniprot.org/uniprot/Q2UCH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA2/NAM7 helicase family.|||Cytoplasm http://togogenome.org/gene/510516:AO090003000018 ^@ http://purl.uniprot.org/uniprot/Q2UMF7 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/510516:AO090023000668 ^@ http://purl.uniprot.org/uniprot/Q2UGX9 ^@ Similarity ^@ Belongs to the synembryn family. http://togogenome.org/gene/510516:AO090001000524 ^@ http://purl.uniprot.org/uniprot/Q2UN32 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.|||Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090011000707 ^@ http://purl.uniprot.org/uniprot/Q2TZV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MGM101 family.|||mitochondrion nucleoid http://togogenome.org/gene/510516:AO090003000126 ^@ http://purl.uniprot.org/uniprot/Q2UM62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/510516:AO090003000439 ^@ http://purl.uniprot.org/uniprot/Q2ULE7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer. http://togogenome.org/gene/510516:AO090020000357 ^@ http://purl.uniprot.org/uniprot/Q2U4G1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090012000401 ^@ http://purl.uniprot.org/uniprot/Q2UCY1 ^@ Similarity ^@ Belongs to the palC family. http://togogenome.org/gene/510516:AO090003000921 ^@ http://purl.uniprot.org/uniprot/Q2UK78 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS7 family. http://togogenome.org/gene/510516:AO090003001408 ^@ http://purl.uniprot.org/uniprot/Q2UJ03 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 76 family. http://togogenome.org/gene/510516:AO090003000895 ^@ http://purl.uniprot.org/uniprot/Q2UKA2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL15 family. http://togogenome.org/gene/510516:AO090012000565 ^@ http://purl.uniprot.org/uniprot/Q2UCJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/510516:AO090023000149 ^@ http://purl.uniprot.org/uniprot/Q2UI89 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/510516:AO090003000505 ^@ http://purl.uniprot.org/uniprot/Q2UL89 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Dus family. Dus3 subfamily.|||Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs (By similarity). Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity).|||Cytoplasm|||Nucleus http://togogenome.org/gene/510516:AO090020000013 ^@ http://purl.uniprot.org/uniprot/Q2U5A2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping by activating the decapping enzyme DCP1. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity).|||Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.|||P-body|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/510516:AO090005001602 ^@ http://purl.uniprot.org/uniprot/Q2UPK8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PLPL family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Probable lipid hydrolase. http://togogenome.org/gene/510516:AO090010000514 ^@ http://purl.uniprot.org/uniprot/Q2TWL2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/510516:AO090009000672 ^@ http://purl.uniprot.org/uniprot/Q2UTM6 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/510516:AO090023000760 ^@ http://purl.uniprot.org/uniprot/Q2UGQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SWC3 family.|||Nucleus http://togogenome.org/gene/510516:AO090023000011 ^@ http://purl.uniprot.org/uniprot/Q2UIL4 ^@ Similarity ^@ Belongs to the flavin monoamine oxidase family. http://togogenome.org/gene/510516:AO090005000648 ^@ http://purl.uniprot.org/uniprot/Q2URX9 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/510516:AO090023000812 ^@ http://purl.uniprot.org/uniprot/Q2UGK1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat WDR12/YTM1 family.|||Component of the NOP7 complex, composed of erb1, nop7 and ytm1. The complex is held together by erb1, which interacts with nop7 via its N-terminal domain and with ytm1 via a high-affinity interaction between the seven-bladed beta-propeller domains of the 2 proteins. The NOP7 complex associates with the 66S pre-ribosome. Interacts (via UBL domain) with mdn1 (via VWFA/MIDAS domain).|||Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.|||nucleolus|||nucleoplasm http://togogenome.org/gene/510516:AO090020000674 ^@ http://purl.uniprot.org/uniprot/Q2U3P7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090009000630 ^@ http://purl.uniprot.org/uniprot/Q2UTR0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.|||Mitochondrion matrix http://togogenome.org/gene/510516:AO090023000133 ^@ http://purl.uniprot.org/uniprot/Q2UIA4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090012000556 ^@ http://purl.uniprot.org/uniprot/Q2UCJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COPE family.|||Cytoplasm|||Membrane http://togogenome.org/gene/510516:AO090026000097 ^@ http://purl.uniprot.org/uniprot/Q2UFS2 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/510516:AO090023000039 ^@ http://purl.uniprot.org/uniprot/Q2UII8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005001086 ^@ http://purl.uniprot.org/uniprot/Q2UQV5 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/510516:AO090010000744 ^@ http://purl.uniprot.org/uniprot/Q2TW12 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/510516:AO090026000517 ^@ http://purl.uniprot.org/uniprot/Q2UER1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase F subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1).|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.|||Vacuole membrane http://togogenome.org/gene/510516:AO090005001045 ^@ http://purl.uniprot.org/uniprot/Q2UQZ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SWC5 family.|||Component of the SWR1 chromatin remodeling complex.|||Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability.|||Nucleus http://togogenome.org/gene/510516:AO090038000528 ^@ http://purl.uniprot.org/uniprot/Q2U2B2 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/510516:AO090011000673 ^@ http://purl.uniprot.org/uniprot/Q2TZY0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 1 family.|||Binds 1 Ca(2+) ion per subunit.|||Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090124000047 ^@ http://purl.uniprot.org/uniprot/Q2U768 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) per subunit.|||Homotetramer. http://togogenome.org/gene/510516:AO090102000198 ^@ http://purl.uniprot.org/uniprot/Q2UAX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090026000365 ^@ http://purl.uniprot.org/uniprot/Q2UF36 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090009000049 ^@ http://purl.uniprot.org/uniprot/Q2UV47 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090020000089 ^@ http://purl.uniprot.org/uniprot/Q2U537 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MATALPHA1 family.|||Nucleus http://togogenome.org/gene/510516:AO090026000033 ^@ http://purl.uniprot.org/uniprot/Q2UFY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090026000224 ^@ http://purl.uniprot.org/uniprot/Q2UFF9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003001097 ^@ http://purl.uniprot.org/uniprot/Q2UJS3 ^@ Function|||Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family.|||Belongs to the NRP synthetase family.|||Catalyzes the activation of alpha-aminoadipate by ATP-dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH. The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate. http://togogenome.org/gene/510516:AO090023000697 ^@ http://purl.uniprot.org/uniprot/Q2UGV3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/510516:AO090701000600 ^@ http://purl.uniprot.org/uniprot/Q2U824 ^@ Similarity ^@ Belongs to the tryptophan dimethylallyltransferase family. http://togogenome.org/gene/510516:AO090010000219 ^@ http://purl.uniprot.org/uniprot/Q2TXA7 ^@ Disruption Phenotype|||Function|||Induction|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.|||Cell membrane|||Expression is highly up-regulated in azole resistant strains and in the presence of miconazole.|||Leads to slight miconazole susceptibility.|||Pleiotropic ABC efflux transporter involved in the basal level of azole susceptibility (PubMed:30011258). Confers resistance to miconazole and clotrimazole (PubMed:30011258). http://togogenome.org/gene/510516:AO090005000044 ^@ http://purl.uniprot.org/uniprot/Q2UTF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090102000559 ^@ http://purl.uniprot.org/uniprot/Q2UA37 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/510516:AO090010000160 ^@ http://purl.uniprot.org/uniprot/Q2TXG1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. CAR1 family.|||MFS-type transporter; part of the gene cluster that mediates the biosynthesis of oryzines, natural products with an unusual maleidride backbone.|||Membrane http://togogenome.org/gene/510516:AO090023000455 ^@ http://purl.uniprot.org/uniprot/Q2UHG5 ^@ Similarity ^@ Belongs to the PrpF family. http://togogenome.org/gene/510516:AO090103000178 ^@ http://purl.uniprot.org/uniprot/Q2TYN3 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. http://togogenome.org/gene/510516:AO090010000673 ^@ http://purl.uniprot.org/uniprot/Q2TW76 ^@ Similarity ^@ Belongs to the SUA5 family. http://togogenome.org/gene/510516:AO090003000845 ^@ http://purl.uniprot.org/uniprot/Q2UKE1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090701000077 ^@ http://purl.uniprot.org/uniprot/Q2U9D1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H3 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/510516:AO090023000890 ^@ http://purl.uniprot.org/uniprot/Q2UGC8 ^@ Similarity ^@ Belongs to the RAD52 family. http://togogenome.org/gene/510516:AO090009000374 ^@ http://purl.uniprot.org/uniprot/Q2UUC2 ^@ Similarity ^@ Belongs to the NmrA-type oxidoreductase family. http://togogenome.org/gene/510516:AO090012000342 ^@ http://purl.uniprot.org/uniprot/Q2UD30 ^@ Similarity ^@ Belongs to the NmrA-type oxidoreductase family. http://togogenome.org/gene/510516:AO090701000108 ^@ http://purl.uniprot.org/uniprot/Q2U9A5 ^@ Function|||Similarity ^@ Belongs to the MnmG family.|||Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs. http://togogenome.org/gene/510516:AO090026000256 ^@ http://purl.uniprot.org/uniprot/Q2UFC8 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/510516:AO090003001032 ^@ http://purl.uniprot.org/uniprot/Q2UJX7 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/510516:AO090005001232 ^@ http://purl.uniprot.org/uniprot/Q2UQI5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||Membrane http://togogenome.org/gene/510516:AO090120000210 ^@ http://purl.uniprot.org/uniprot/Q2U6J5 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. MetX family. http://togogenome.org/gene/510516:AO090011000625 ^@ http://purl.uniprot.org/uniprot/Q2U018 ^@ Similarity ^@ Belongs to the SPT2 family. http://togogenome.org/gene/510516:AO090011000469 ^@ http://purl.uniprot.org/uniprot/Q2U0E6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SRP14 family.|||Component of a fungal signal recognition particle (SRP) complex that consists of a 7SL RNA molecule (scR1) and at least six protein subunits: SRP72, SRP68, SRP54, SEC65, SRP21 and SRP14.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).|||Cytoplasm http://togogenome.org/gene/510516:AO090010000612 ^@ http://purl.uniprot.org/uniprot/Q2TWD0 ^@ Similarity ^@ Belongs to the glycosyltransferase 32 family. http://togogenome.org/gene/510516:AO090005001109 ^@ http://purl.uniprot.org/uniprot/Q2UQT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20A family.|||Secreted http://togogenome.org/gene/510516:AO090001000692 ^@ http://purl.uniprot.org/uniprot/Q2UMN3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090020000291 ^@ http://purl.uniprot.org/uniprot/Q2U4L5 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. http://togogenome.org/gene/510516:AO090020000699 ^@ http://purl.uniprot.org/uniprot/Q2U3M3 ^@ Similarity ^@ Belongs to the DSD1 family. http://togogenome.org/gene/510516:AO090009000698 ^@ http://purl.uniprot.org/uniprot/Q2UTK2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL23 family. http://togogenome.org/gene/510516:AO090120000196 ^@ http://purl.uniprot.org/uniprot/P0C1B3 ^@ Biotechnology|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family.|||Binds 2 calcium ions per subunit (PubMed:6609921, PubMed:9283074, PubMed:16880540). Calcium is inhibitory at high concentrations.|||Monomer.|||Secreted|||Used in the brewing industry to increase the fermentability of beer worts (including those made from unmalted cereals), in the starch industry to make high maltose and high DE syrups (starch saccharification), in the alcohol industry to reduce fermentation time, in the cereal food industry for flour supplementation and improvement of chilled and frozen dough, and in the forestry industry for low-temperature modification of starch. Sold under the name Fungamyl by Novozymes. http://togogenome.org/gene/510516:AO090023000096 ^@ http://purl.uniprot.org/uniprot/Q2UID7 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. http://togogenome.org/gene/510516:AO090120000327 ^@ http://purl.uniprot.org/uniprot/Q2U696 ^@ Activity Regulation|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.|||Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.|||In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.|||Nucleus|||Ubiquitination of histone H2B to form H2BK123ub1 is required for efficient DOT1 methyltransferase activity on histone H3. http://togogenome.org/gene/510516:AO090012000090 ^@ http://purl.uniprot.org/uniprot/Q2UDP5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 61 family.|||Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM). The genes for catalytic modules and CBMs seem to have evolved separately and have been linked by gene fusion.|||Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds. Involved in the degradation of complex natural cellulosic substrates.|||Secreted http://togogenome.org/gene/510516:AO090005000471 ^@ http://purl.uniprot.org/uniprot/Q2USD6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090012000435 ^@ http://purl.uniprot.org/uniprot/Q2UCV2 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. http://togogenome.org/gene/510516:AO090005000447 ^@ http://purl.uniprot.org/uniprot/P80402 ^@ Function|||Similarity|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily.|||Has an absolute substrate specificity for 2,3-DHBA.|||Homotetramer. http://togogenome.org/gene/510516:AO090009000090 ^@ http://purl.uniprot.org/uniprot/Q2UV15 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090003000570 ^@ http://purl.uniprot.org/uniprot/Q2UL30 ^@ Similarity ^@ Belongs to the GHMP kinase family. GalK subfamily. http://togogenome.org/gene/510516:AO090120000215 ^@ http://purl.uniprot.org/uniprot/Q2U6J1 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/510516:AO090102000150 ^@ http://purl.uniprot.org/uniprot/Q2UB16 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.|||Belongs to the NMD3 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/510516:AO090012000872 ^@ http://purl.uniprot.org/uniprot/Q2UBT5 ^@ Similarity ^@ Belongs to the VPS37 family. http://togogenome.org/gene/510516:AO090138000010 ^@ http://purl.uniprot.org/uniprot/Q2U214 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/510516:AO090010000132 ^@ http://purl.uniprot.org/uniprot/Q2TXI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FMP52 family.|||Mitochondrion outer membrane http://togogenome.org/gene/510516:AO090026000134 ^@ http://purl.uniprot.org/uniprot/Q2UFN7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity).|||Belongs to the ATG17 family.|||Cytoplasm|||Preautophagosomal structure membrane http://togogenome.org/gene/510516:AO090701000015 ^@ http://purl.uniprot.org/uniprot/Q2U9I7 ^@ Similarity ^@ Belongs to the UPF0357 family. http://togogenome.org/gene/510516:AO090012000573 ^@ http://purl.uniprot.org/uniprot/Q2UCI6 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/510516:AO090102000614 ^@ http://purl.uniprot.org/uniprot/Q2U9Y6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/510516:AO090020000019 ^@ http://purl.uniprot.org/uniprot/Q2U598 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/510516:AO090038000610 ^@ http://purl.uniprot.org/uniprot/Q2U242 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/510516:AO090120000355 ^@ http://purl.uniprot.org/uniprot/Q2U672 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090011000870 ^@ http://purl.uniprot.org/uniprot/Q2TZF6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000996 ^@ http://purl.uniprot.org/uniprot/Q2UR29 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TCTP family.|||Involved in protein synthesis. Involved in microtubule stabilization (By similarity).|||cytoskeleton http://togogenome.org/gene/510516:AO090005000816 ^@ http://purl.uniprot.org/uniprot/Q2URI4 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/510516:AO090010000520 ^@ http://purl.uniprot.org/uniprot/Q2TWK6 ^@ Similarity ^@ Belongs to the amino acid/polyamine transporter 2 family. http://togogenome.org/gene/510516:AO090023000382 ^@ http://purl.uniprot.org/uniprot/Q2UHN1 ^@ Similarity ^@ Belongs to the peptidase S10 family. http://togogenome.org/gene/510516:AO090009000558 ^@ http://purl.uniprot.org/uniprot/Q2UTX1 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/510516:AO090026000136 ^@ http://purl.uniprot.org/uniprot/Q2UFN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family. SMC3 subfamily.|||Nucleus http://togogenome.org/gene/510516:AO090012000770 ^@ http://purl.uniprot.org/uniprot/Q2UC26 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/510516:AO090003001410 ^@ http://purl.uniprot.org/uniprot/Q2UJ01 ^@ Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 2 family.|||Monomer. http://togogenome.org/gene/510516:AO090005001630 ^@ http://purl.uniprot.org/uniprot/Q2UPI3 ^@ Function|||Similarity ^@ Belongs to the endosulfine family.|||Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway. http://togogenome.org/gene/510516:AO090102000355 ^@ http://purl.uniprot.org/uniprot/Q2UAJ9 ^@ Similarity ^@ Belongs to the ATP-dependent DNA ligase family. http://togogenome.org/gene/510516:AO090011000917 ^@ http://purl.uniprot.org/uniprot/Q2TZB9 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/510516:AO090102000393 ^@ http://purl.uniprot.org/uniprot/Q2UAG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family.|||Membrane http://togogenome.org/gene/510516:AO090012001021 ^@ http://purl.uniprot.org/uniprot/Q2UBF4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 39 family.|||Endoplasmic reticulum membrane|||Membrane|||Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. http://togogenome.org/gene/510516:AO090023000569 ^@ http://purl.uniprot.org/uniprot/Q2UH63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/510516:AO090701000172 ^@ http://purl.uniprot.org/uniprot/Q2U951 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/510516:AO090011000114 ^@ http://purl.uniprot.org/uniprot/Q2U198 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090010000205 ^@ http://purl.uniprot.org/uniprot/Q2TXC0 ^@ Similarity ^@ Belongs to the peptidase C12 family. http://togogenome.org/gene/510516:AO090001000042 ^@ http://purl.uniprot.org/uniprot/Q2UPB0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.|||Dipeptidase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411). The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411). One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411). After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411). In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411). Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411).|||Membrane http://togogenome.org/gene/510516:AO090009000691 ^@ http://purl.uniprot.org/uniprot/Q2UTK8 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruB family. http://togogenome.org/gene/510516:AO090012000888 ^@ http://purl.uniprot.org/uniprot/Q2UBS2 ^@ Function|||Similarity ^@ Belongs to the transferase hexapeptide repeat family.|||Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint. http://togogenome.org/gene/510516:AO090023000099 ^@ http://purl.uniprot.org/uniprot/Q2UID4 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. http://togogenome.org/gene/510516:AO090103000118 ^@ http://purl.uniprot.org/uniprot/Q2TYT4 ^@ Similarity ^@ Belongs to the flavin monoamine oxidase family. http://togogenome.org/gene/510516:AO090023000142 ^@ http://purl.uniprot.org/uniprot/Q2UI95 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/510516:AO090701000397 ^@ http://purl.uniprot.org/uniprot/Q2U8K6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. May also be involved in early transcription (By similarity).|||Associates with the nuclear pore complex.|||Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.|||Cytoplasm|||Nucleus membrane|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.|||nuclear pore complex http://togogenome.org/gene/510516:AO090009000579 ^@ http://purl.uniprot.org/uniprot/Q2UTV2 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/510516:AO090206000026 ^@ http://purl.uniprot.org/uniprot/Q2PIX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Membrane http://togogenome.org/gene/510516:AO090005000337 ^@ http://purl.uniprot.org/uniprot/Q2USQ4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/510516:AO090009000707 ^@ http://purl.uniprot.org/uniprot/Q2UTJ6 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/510516:AO090166000079 ^@ http://purl.uniprot.org/uniprot/Q2U9N5 ^@ Similarity ^@ Belongs to the tannase family. http://togogenome.org/gene/510516:AO090010000730 ^@ http://purl.uniprot.org/uniprot/Q2TW26 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090012000496 ^@ http://purl.uniprot.org/uniprot/Q2UCP9|||http://purl.uniprot.org/uniprot/Q76MU7 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Glutarylation at Lys-92 (H4K91glu) destabilizes nucleosomes by promoting dissociation of the H2A-H2B dimers from nucleosomes.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/510516:AO090701000208 ^@ http://purl.uniprot.org/uniprot/Q2U919 ^@ Similarity ^@ Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily. http://togogenome.org/gene/510516:AO090020000158 ^@ http://purl.uniprot.org/uniprot/Q2U4Y0 ^@ Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family. http://togogenome.org/gene/510516:AO090038000449 ^@ http://purl.uniprot.org/uniprot/Q2U2I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/510516:AO090001000500 ^@ http://purl.uniprot.org/uniprot/Q2UN54 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.|||Binds 1 FAD per subunit.|||Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090120000141 ^@ http://purl.uniprot.org/uniprot/Q2U6Q2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090120000044 ^@ http://purl.uniprot.org/uniprot/Q2U6Y4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090005000878 ^@ http://purl.uniprot.org/uniprot/Q2URD0 ^@ Similarity ^@ Belongs to the BRX1 family. http://togogenome.org/gene/510516:AO090003000687 ^@ http://purl.uniprot.org/uniprot/Q2UKT1 ^@ Similarity|||Subunit ^@ Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.|||Homotetramer. http://togogenome.org/gene/510516:AO090026000543 ^@ http://purl.uniprot.org/uniprot/Q2UEP1 ^@ Similarity|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Homodimer. http://togogenome.org/gene/510516:AO090026000235 ^@ http://purl.uniprot.org/uniprot/Q2UFE9 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090011000209 ^@ http://purl.uniprot.org/uniprot/Q2U117 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090001000728 ^@ http://purl.uniprot.org/uniprot/Q2UMJ7 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/510516:AO090003001373 ^@ http://purl.uniprot.org/uniprot/Q2UJ34 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090011000473 ^@ http://purl.uniprot.org/uniprot/Q2U0E2 ^@ Similarity ^@ Belongs to the MSOX/MTOX family. http://togogenome.org/gene/510516:AO090120000175 ^@ http://purl.uniprot.org/uniprot/Q2U6M5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.|||Membrane http://togogenome.org/gene/510516:AO090003000477 ^@ http://purl.uniprot.org/uniprot/Q2ULB1 ^@ Similarity ^@ In the C-terminal section; belongs to the histidinol dehydrogenase family. http://togogenome.org/gene/510516:AO090010000760 ^@ http://purl.uniprot.org/uniprot/Q2TVZ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GNT1 family.|||Golgi apparatus membrane|||Membrane|||N-acetylglucosaminyltransferase involved in the Golgi-specific modification of N-linked glycans.|||Vacuole membrane http://togogenome.org/gene/510516:AO090701000589 ^@ http://purl.uniprot.org/uniprot/Q2U834 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the chitin synthase family.|||Cell membrane|||Membrane|||Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer. http://togogenome.org/gene/510516:AO090012000444 ^@ http://purl.uniprot.org/uniprot/Q2UCU4 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/510516:AO090038000416 ^@ http://purl.uniprot.org/uniprot/Q2U2K9 ^@ Similarity ^@ Belongs to the PhyH family. http://togogenome.org/gene/510516:AO090701000226 ^@ http://purl.uniprot.org/uniprot/Q2U902 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.|||Cytoplasm|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.|||In the N-terminal section; belongs to the flavodoxin family.|||Interacts with DRE2; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mitochondrion|||NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of DRE2, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. Positively controls H(2)O(2)-induced cell death. http://togogenome.org/gene/510516:AO090001000237 ^@ http://purl.uniprot.org/uniprot/Q2UNT7 ^@ Disruption Phenotype|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the velvet family. VeA subfamily.|||Component of the heterotrimeric velvet complex composed of laeA, veA and velB; VeA acting as a bridging protein between laeA and velB (By similarity).|||Component of the velvet transcription factor complex that controls sexual/asexual developmental ratio in response to light, promoting sexual development in the darkness while stimulating asexual sporulation under illumination (By similarity). The velvet complex hat acts as a global regulator for secondary metabolite gene expression (PubMed:20541108). Controls the expression of the penicillin gene cluster (PubMed:20541108).|||Cytoplasm|||Nucleus|||Reduces the production of penicillin (PubMed:20541108).|||The C-terminal PEST domain is a region rich in proline, glutamic acid, serine and threonine residues that is required for the light-dependent regulation of development and secondary metabolism (By similarity). http://togogenome.org/gene/510516:AO090038000096 ^@ http://purl.uniprot.org/uniprot/Q2U3C6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the steroid 5-alpha reductase family.|||Membrane http://togogenome.org/gene/510516:AO090026000581 ^@ http://purl.uniprot.org/uniprot/Q2UEK5 ^@ Disruption Phenotype|||Function|||Induction|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of astellolides, drimane-type sesquiterpene esters that show antimicrobial, anti-inflammatory, and anti-tumor activities (PubMed:27628599). The first step in astellolide biosynthesis is performed by the sesquiterpene cyclase astC that catalyzes the formation of drimanyl pyrophosphate from farnesyl pyrophosphate (PubMed:27628599). Drimanyl pyrophosphate is then dephosphorylated by the sesquiterpene phosphatase astI to produce drimanyl monophosphate which is further dephosphorylated to drim-8-ene-11-ol by atsK (PubMed:27628599). Drim-8-ene-11-ol is converted to confertifolin, probably by the cytochrome P450 monooxygenase astD and/or the dehydrogenase astE (PubMed:27628599). The cytochrome P450 monooxygenases astB, astF and astJ then hydroxylate confertifolin at C6, C14, or C15 to form trihydroxy confertifolin (PubMed:27628599). The nonribosomal peptide synthetase astA catalyzes ester bond formation between trihydroxy contifolin and benzoic acid (BA) or 4-hydroxy benzoic acid (4HBA), leading to the formation of dideacetyl astellolides A and B, respectively (PubMed:27628599). Finally, the O-acetyltransferase astG converts dideacetyl astellolides A and B into deacetyl astellolides A and B (PubMed:27628599).|||Expression is regulated by the secondary metabolite regulator cclA.|||Leads to the loss of intermediates such as confertifolin.|||Membrane http://togogenome.org/gene/510516:AO090010000705 ^@ http://purl.uniprot.org/uniprot/Q2TW50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/510516:AO090038000206 ^@ http://purl.uniprot.org/uniprot/Q2U337 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090011000483 ^@ http://purl.uniprot.org/uniprot/Q2U0D5 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/510516:AO090023000654 ^@ http://purl.uniprot.org/uniprot/Q2UGZ1 ^@ Function|||Similarity ^@ Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/510516:AO090012000931 ^@ http://purl.uniprot.org/uniprot/Q2UBN3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL17 family. http://togogenome.org/gene/510516:AO090010000312 ^@ http://purl.uniprot.org/uniprot/Q2TX28 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/510516:AO090023000504 ^@ http://purl.uniprot.org/uniprot/Q2UHC1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.|||Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.|||nucleolus http://togogenome.org/gene/510516:AO090001000550 ^@ http://purl.uniprot.org/uniprot/Q2UN06 ^@ Function|||Similarity ^@ Belongs to the proline oxidase family.|||Converts proline to delta-1-pyrroline-5-carboxylate. http://togogenome.org/gene/510516:AO090102000165 ^@ http://purl.uniprot.org/uniprot/Q2UB01 ^@ Disruption Phenotype|||Function|||Similarity|||Subcellular Location Annotation ^@ Abolishes the production of 2,4'-dihydroxy-3'-methoxypropiophenone and 4'-hydroxy-3'-methoxypropiophenone.|||Acyl-CoA ligase; part of the gene cluster that mediates the biosynthesis of 2,4'-dihydroxy-3'-methoxypropiophenone (PubMed:32885554). The first step of the pathway is the conversion of acetate into acetyl-CoA by the acyl-CoA ligase ppsA (PubMed:32885554). Acetyl-CoA is then used as a starter unit by the polyketide synthase ppsB and condensed with 4 malonyl-CoA unit to produce the pentaketide backbone (PubMed:32885554). During polyketide extension, the polykedite chain is probably reduced and dehydrated by the KR and PT domains, respectively (Probable). O-methylation seems to be catalyzed by an unknown methyltransferase rather than by the CMeT domain of ppsB (Probable). Two hydroxylations and one further decarboxylation step catalyzed by yet unknown enzymes are then required to yield 4'-hydroxy-3'-methoxypropiophenone (Probable). PpsC functions as a carrier protein to transport 4'-hydroxy-3'-methoxypropiophenone to a specific cell compartment in which 4'-hydroxy-3'-methoxypropiophenone is hydroxylated to 2,4'-dihydroxy-3'-methoxypropiophenone by a still to be identified enzyme (PubMed:32885554).|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Membrane http://togogenome.org/gene/510516:AO090102000627 ^@ http://purl.uniprot.org/uniprot/Q2U9X4 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/510516:AO090010000330 ^@ http://purl.uniprot.org/uniprot/Q2TX11 ^@ Similarity ^@ Belongs to the class-A beta-lactamase family. http://togogenome.org/gene/510516:AO090009000014 ^@ http://purl.uniprot.org/uniprot/Q2UV76 ^@ Similarity ^@ Belongs to the class-A beta-lactamase family. http://togogenome.org/gene/510516:AO090020000618 ^@ http://purl.uniprot.org/uniprot/Q2U3U2 ^@ Similarity ^@ Belongs to the indoleamine 2,3-dioxygenase family. http://togogenome.org/gene/510516:AO090026000513 ^@ http://purl.uniprot.org/uniprot/Q2UER5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATG22 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.|||Vacuole membrane http://togogenome.org/gene/510516:AO090001000167 ^@ http://purl.uniprot.org/uniprot/Q2UNZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERG4/ERG24 family.|||Membrane http://togogenome.org/gene/510516:AO090005001649 ^@ http://purl.uniprot.org/uniprot/Q2UPG7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YPI1 family.|||Nucleus|||Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control. http://togogenome.org/gene/510516:AO090001000065 ^@ http://purl.uniprot.org/uniprot/Q2UP90 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090206000094 ^@ http://purl.uniprot.org/uniprot/Q2PIR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090038000434 ^@ http://purl.uniprot.org/uniprot/Q2U2J2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/510516:AO090701000552 ^@ http://purl.uniprot.org/uniprot/Q2U865 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090138000004 ^@ http://purl.uniprot.org/uniprot/Q2U220 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 61 family.|||Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM). The genes for catalytic modules and CBMs seem to have evolved separately and have been linked by gene fusion.|||Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds. Involved in the degradation of complex natural cellulosic substrates.|||Secreted http://togogenome.org/gene/510516:AO090102000555 ^@ http://purl.uniprot.org/uniprot/Q2UA41 ^@ Similarity ^@ Belongs to the thymidylate kinase family. http://togogenome.org/gene/510516:AO090003000963 ^@ http://purl.uniprot.org/uniprot/Q2UK39 ^@ Similarity ^@ Belongs to the NFYB/HAP3 subunit family. http://togogenome.org/gene/510516:AO090003000235 ^@ http://purl.uniprot.org/uniprot/Q2ULX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090701000588 ^@ http://purl.uniprot.org/uniprot/Q2U835 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/510516:AO090003000478 ^@ http://purl.uniprot.org/uniprot/Q2ULB0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UTP11 family.|||Component of the ribosomal small subunit (SSU) processome.|||Involved in nucleolar processing of pre-18S ribosomal RNA.|||nucleolus http://togogenome.org/gene/510516:AO090011000036 ^@ http://purl.uniprot.org/uniprot/Q2U1G7 ^@ Cofactor|||Function|||Induction|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M36 family.|||Binds 1 zinc ion per subunit.|||Expression is controlled by the prtT transcription factor.|||Secreted|||Secreted metalloproteinase that allows assimilation of proteinaceous substrates. http://togogenome.org/gene/510516:AO090023000161 ^@ http://purl.uniprot.org/uniprot/P35335 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 28 family.|||Involved in maceration and soft-rotting of plant tissue. Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall.|||Secreted http://togogenome.org/gene/510516:AO090011000055 ^@ http://purl.uniprot.org/uniprot/Q2U1F0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family. http://togogenome.org/gene/510516:AO090009000686 ^@ http://purl.uniprot.org/uniprot/Q2UTL3 ^@ Similarity ^@ Belongs to the KNR4/SMI1 family. http://togogenome.org/gene/510516:AO090012000617 ^@ http://purl.uniprot.org/uniprot/Q2UCF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/510516:AO090023000314 ^@ http://purl.uniprot.org/uniprot/Q2UHT9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 3-HAO family.|||Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.|||Cytoplasm http://togogenome.org/gene/510516:AO090012000752 ^@ http://purl.uniprot.org/uniprot/Q2UC40 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) per subunit.|||Homotetramer. http://togogenome.org/gene/510516:AO090005001282 ^@ http://purl.uniprot.org/uniprot/Q2UQE5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090005001248 ^@ http://purl.uniprot.org/uniprot/Q2UQH2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/510516:AO090003001461 ^@ http://purl.uniprot.org/uniprot/Q2UIV6 ^@ Similarity ^@ Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. http://togogenome.org/gene/510516:AO090010000062 ^@ http://purl.uniprot.org/uniprot/Q2TXP7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090120000418 ^@ http://purl.uniprot.org/uniprot/Q2U616 ^@ Disruption Phenotype|||Function|||Induction|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. ATF subfamily.|||Expression is barely detectable at the basal hyphal growth phase but induced during conidial development (PubMed:18448366).|||Leads to weak conidia formation on hyperosmotic medium (PubMed:18448366).|||Nucleus|||Transcription factor that acts as a key player in the regulatory circuit that integrates secondary metabolism and cellular response to oxidative stress (By similarity). Regulates the genes involved in development and stress response through direct binding to their promoters (PubMed:18448366). Particularly involved in the resistance to oxidative stress in asexual conidiospores (PubMed:18448366). http://togogenome.org/gene/510516:AO090701000235 ^@ http://purl.uniprot.org/uniprot/Q2U8Z3 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. MetX family. http://togogenome.org/gene/510516:AO090005000420 ^@ http://purl.uniprot.org/uniprot/Q2USH9 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/510516:AO090020000073 ^@ http://purl.uniprot.org/uniprot/Q2U549 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/510516:AO090026000346 ^@ http://purl.uniprot.org/uniprot/Q2UF51 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/510516:AO090005001530 ^@ http://purl.uniprot.org/uniprot/Q2UPS3 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/510516:AO090026000614 ^@ http://purl.uniprot.org/uniprot/Q2UEH7 ^@ Disruption Phenotype|||Function|||Subcellular Location Annotation ^@ Membrane|||Nucleus|||Results in a hypersensitivity to miconazole.|||Transcription factor that regulates expression of the genes related to resistance to azole compounds. http://togogenome.org/gene/510516:AO090005000919 ^@ http://purl.uniprot.org/uniprot/Q2UR92 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/510516:AO090005001354 ^@ http://purl.uniprot.org/uniprot/Q2UQ84 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. http://togogenome.org/gene/510516:AO090001000665 ^@ http://purl.uniprot.org/uniprot/Q2UMQ4 ^@ Similarity ^@ Belongs to the CEF1 family. http://togogenome.org/gene/510516:AO090038000122 ^@ http://purl.uniprot.org/uniprot/Q2U3A3 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/510516:AO090005001092 ^@ http://purl.uniprot.org/uniprot/Q2UQV0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Cytoplasm|||Maintains high levels of reduced glutathione in the cytosol. http://togogenome.org/gene/510516:AO090009000294 ^@ http://purl.uniprot.org/uniprot/Q2UUJ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UbiH/COQ6 family.|||Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.|||FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090003001409 ^@ http://purl.uniprot.org/uniprot/Q2UJ02 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/510516:AO090011000825 ^@ http://purl.uniprot.org/uniprot/Q2TZJ8 ^@ Similarity ^@ Belongs to the DNA/RNA non-specific endonuclease family. http://togogenome.org/gene/510516:AO090009000380 ^@ http://purl.uniprot.org/uniprot/Q2UUB6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000436 ^@ http://purl.uniprot.org/uniprot/Q2USG5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||Mitochondrion|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/510516:AO090038000339 ^@ http://purl.uniprot.org/uniprot/Q2U2S4 ^@ Similarity ^@ Belongs to the amino acid/polyamine transporter 2 family. http://togogenome.org/gene/510516:AO090026000283 ^@ http://purl.uniprot.org/uniprot/Q2UFA6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex. http://togogenome.org/gene/510516:AO090005000034 ^@ http://purl.uniprot.org/uniprot/Q2UTG0 ^@ Function|||Similarity ^@ Belongs to the proline oxidase family.|||Converts proline to delta-1-pyrroline-5-carboxylate. http://togogenome.org/gene/510516:AO090038000400 ^@ http://purl.uniprot.org/uniprot/Q2U2M2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090120000341 ^@ http://purl.uniprot.org/uniprot/Q2U684 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/510516:AO090003001133 ^@ http://purl.uniprot.org/uniprot/Q2UJP1 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/510516:AO090003000239 ^@ http://purl.uniprot.org/uniprot/Q2ULW8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/510516:AO090003000506 ^@ http://purl.uniprot.org/uniprot/Q2UL88 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BCAP29/BCAP31 family.|||Endoplasmic reticulum membrane|||May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.|||Membrane http://togogenome.org/gene/510516:AO090003001199 ^@ http://purl.uniprot.org/uniprot/Q2UJI4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090010000669 ^@ http://purl.uniprot.org/uniprot/Q2TW80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HRI1 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/510516:AO090120000370 ^@ http://purl.uniprot.org/uniprot/Q2U658 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. http://togogenome.org/gene/510516:AO090023000110 ^@ http://purl.uniprot.org/uniprot/Q2UIC6 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/510516:AO090009000621 ^@ http://purl.uniprot.org/uniprot/Q2UTR8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/510516:AO090012000345 ^@ http://purl.uniprot.org/uniprot/Q2UD27 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090005000781 ^@ http://purl.uniprot.org/uniprot/Q2URL4 ^@ Similarity ^@ Belongs to the pyridoxine kinase family. http://togogenome.org/gene/510516:AO090038000356 ^@ http://purl.uniprot.org/uniprot/Q2U2Q8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/510516:AO090124000026 ^@ http://purl.uniprot.org/uniprot/Q2U787 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090011000304 ^@ http://purl.uniprot.org/uniprot/Q2U0U2 ^@ Similarity ^@ Belongs to the NmrA-type oxidoreductase family. http://togogenome.org/gene/510516:AO090010000582 ^@ http://purl.uniprot.org/uniprot/Q2TWF5 ^@ Function|||Similarity ^@ Belongs to the alpha-carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/510516:AO090003001381 ^@ http://purl.uniprot.org/uniprot/Q2UJ26 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090701000797 ^@ http://purl.uniprot.org/uniprot/Q2U7L0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ERGIC family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Golgi apparatus membrane|||Plays a role in transport between endoplasmic reticulum and Golgi. http://togogenome.org/gene/510516:AO090003000752 ^@ http://purl.uniprot.org/uniprot/Q2UKM2 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/510516:AO090103000132 ^@ http://purl.uniprot.org/uniprot/Q2TYS1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090003000546 ^@ http://purl.uniprot.org/uniprot/Q2UL52 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TBP family.|||Nucleus http://togogenome.org/gene/510516:AO090005000812 ^@ http://purl.uniprot.org/uniprot/Q2URI7 ^@ Similarity ^@ Belongs to the WrbA family. http://togogenome.org/gene/510516:AO090701000280 ^@ http://purl.uniprot.org/uniprot/Q2U8V3 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/510516:AO090009000356 ^@ http://purl.uniprot.org/uniprot/Q2UUD6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 3 family.|||Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090012000993 ^@ http://purl.uniprot.org/uniprot/Q2UBH9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090113000004 ^@ http://purl.uniprot.org/uniprot/Q2U5U3 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/510516:AO090103000481 ^@ http://purl.uniprot.org/uniprot/Q2TXX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090701000122 ^@ http://purl.uniprot.org/uniprot/Q2U994 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/510516:AO090005001430 ^@ http://purl.uniprot.org/uniprot/Q2UQ11 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090012000417 ^@ http://purl.uniprot.org/uniprot/Q2UCW7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/510516:AO090020000669 ^@ http://purl.uniprot.org/uniprot/Q2U3Q1 ^@ Similarity ^@ Belongs to the SMP-30/CGR1 family. http://togogenome.org/gene/510516:AO090120000340 ^@ http://purl.uniprot.org/uniprot/Q2U685 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MUB1/samB family.|||Cytoplasm|||Involved in determination of the onset of polarized growth and morphogenesis. Plays a role in the regulation of branching in hyphae and spore formation (By similarity). http://togogenome.org/gene/510516:AO090005001556 ^@ http://purl.uniprot.org/uniprot/Q2UPQ1 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/510516:AO090026000485 ^@ http://purl.uniprot.org/uniprot/Q2UET8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090701000307 ^@ http://purl.uniprot.org/uniprot/Q2U8S8 ^@ Cofactor|||PTM|||Similarity ^@ Belongs to the copper/topaquinone oxidase family.|||Contains 1 topaquinone per subunit.|||Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. http://togogenome.org/gene/510516:AO090020000413 ^@ http://purl.uniprot.org/uniprot/Q2U4B3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm|||Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. http://togogenome.org/gene/510516:AO090026000538 ^@ http://purl.uniprot.org/uniprot/Q2UEP5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the universal ribosomal protein uL29 family.|||Component of the mitochondrial large ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S).|||Mitochondrion http://togogenome.org/gene/510516:AO090001000015 ^@ http://purl.uniprot.org/uniprot/Q2UPD6 ^@ Similarity ^@ Belongs to the MSOX/MTOX family. http://togogenome.org/gene/510516:AO090003001324 ^@ http://purl.uniprot.org/uniprot/Q2UJ80 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetylated once deposited into chromatin.|||Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. H2A or its variant H2A.Z forms a heterodimer with H2B. H2A.Z associates with the vps72/swc2 subunit of the SWR1 chromatin remodeling complex. Interacts also with rbp1/DNA-directed RNA polymerase II largest subunit (By similarity).|||Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received. Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins. Required for the RNA polymerase II and spt15/TBP recruitment to the target genes. Involved in chromosome stability (By similarity). http://togogenome.org/gene/510516:AO090003001376 ^@ http://purl.uniprot.org/uniprot/Q2UJ31 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/510516:AO090012000827 ^@ http://purl.uniprot.org/uniprot/Q2UBX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/510516:AO090005000132 ^@ http://purl.uniprot.org/uniprot/Q2UT72 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the protein prenyltransferase subunit beta family.|||Binds 1 zinc ion per subunit.|||Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX. http://togogenome.org/gene/510516:AO090003000885 ^@ http://purl.uniprot.org/uniprot/Q2UKB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NGG1 family.|||Nucleus http://togogenome.org/gene/510516:AO090012000271 ^@ http://purl.uniprot.org/uniprot/Q2UD90 ^@ Similarity ^@ Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. http://togogenome.org/gene/510516:AO090009000197 ^@ http://purl.uniprot.org/uniprot/Q2UUS4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090120000498 ^@ http://purl.uniprot.org/uniprot/Q2U5V4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL43 family.|||Mitochondrion http://togogenome.org/gene/510516:AO090012000624 ^@ http://purl.uniprot.org/uniprot/Q2UCE5 ^@ Similarity ^@ Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. http://togogenome.org/gene/510516:AO090701000173 ^@ http://purl.uniprot.org/uniprot/Q2U950 ^@ Cofactor|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/510516:AO090026000664 ^@ http://purl.uniprot.org/uniprot/Q2UED4 ^@ Similarity ^@ Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily. http://togogenome.org/gene/510516:AO090011000229 ^@ http://purl.uniprot.org/uniprot/Q2U101 ^@ Cofactor|||PTM|||Similarity ^@ Belongs to the copper/topaquinone oxidase family.|||Contains 1 topaquinone per subunit.|||Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. http://togogenome.org/gene/510516:AO090003000225 ^@ http://purl.uniprot.org/uniprot/Q2ULX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAPT1 family.|||Membrane http://togogenome.org/gene/510516:AO090038000054 ^@ http://purl.uniprot.org/uniprot/Q2U3F9 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/510516:AO090102000298 ^@ http://purl.uniprot.org/uniprot/Q2UAP5 ^@ Similarity ^@ Belongs to the class-A beta-lactamase family. http://togogenome.org/gene/510516:AO090011000116 ^@ http://purl.uniprot.org/uniprot/Q2U196 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090120000312 ^@ http://purl.uniprot.org/uniprot/Q2U6B1 ^@ Similarity|||Subunit ^@ Associated with the spliceosome.|||Belongs to the crooked-neck family. http://togogenome.org/gene/510516:AO090038000452 ^@ http://purl.uniprot.org/uniprot/Q2U2H7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMA20 family.|||Cytoplasm|||Involved in translation. http://togogenome.org/gene/510516:AO090026000133 ^@ http://purl.uniprot.org/uniprot/Q2UFN8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the WD repeat MET30/SCONB/SCON-2 family.|||Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.|||Component of the SCF(sconB) E3 ubiquitin ligase complex. http://togogenome.org/gene/510516:AO090011000493 ^@ http://purl.uniprot.org/uniprot/Q2U0C6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family. SMC4 subfamily.|||Nucleus http://togogenome.org/gene/510516:AO090010000700 ^@ http://purl.uniprot.org/uniprot/Q2TW54 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090026000804 ^@ http://purl.uniprot.org/uniprot/Q2UE10 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/510516:AO090010000186 ^@ http://purl.uniprot.org/uniprot/Q2TXD7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090020000109 ^@ http://purl.uniprot.org/uniprot/Q2U523 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COQ4 family.|||Component of a multi-subunit COQ enzyme complex, composed of at least coq3, coq4, coq5, coq6, coq7 and coq9.|||Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090003000001 ^@ http://purl.uniprot.org/uniprot/Q2UMH4 ^@ Similarity ^@ Belongs to the TRM112 family. http://togogenome.org/gene/510516:AO090001000207 ^@ http://purl.uniprot.org/uniprot/Q2UNW5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. FaeA family.|||Involved in degradation of plant cell walls. Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans, and the feruloyl-galactose ester bond in pectin (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090023001006 ^@ http://purl.uniprot.org/uniprot/Q2UG25 ^@ Subcellular Location Annotation ^@ Mitochondrion inner membrane|||Mitochondrion intermembrane space http://togogenome.org/gene/510516:AO090103000435 ^@ http://purl.uniprot.org/uniprot/Q2TY09 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. http://togogenome.org/gene/510516:AO090010000684 ^@ http://purl.uniprot.org/uniprot/Q2TW69 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycosyl hydrolase 36 family.|||Homotetramer.|||Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.|||Secreted http://togogenome.org/gene/510516:AO090003000922 ^@ http://purl.uniprot.org/uniprot/Q2UK77 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.|||Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.|||Membrane|||Vacuole membrane http://togogenome.org/gene/510516:AO090005000090 ^@ http://purl.uniprot.org/uniprot/Q2UTB1 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/510516:AO090005001121 ^@ http://purl.uniprot.org/uniprot/Q2UQS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/510516:AO090005001150 ^@ http://purl.uniprot.org/uniprot/Q2UQQ2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). http://togogenome.org/gene/510516:AO090003000121 ^@ http://purl.uniprot.org/uniprot/Q2UM66 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/510516:AO090005001523 ^@ http://purl.uniprot.org/uniprot/Q2UPT0 ^@ Function|||Subunit ^@ Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.|||Component of the heptameric LSM1-LSM7 complex, which consists of LSM1, LSM2, LSM3, LSM4, LSM5, LSM6 and LSM7. Component of the heptameric LSM2-LSM8 complex, which consists of LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8. The LSm subunits form a seven-membered ring structure with a doughnut shape. http://togogenome.org/gene/510516:AO090038000296 ^@ http://purl.uniprot.org/uniprot/Q2U2W1 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/510516:AO090701000281 ^@ http://purl.uniprot.org/uniprot/Q2U8V2 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/510516:AO090020000122 ^@ http://purl.uniprot.org/uniprot/Q2U512 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/510516:AO090113000144 ^@ http://purl.uniprot.org/uniprot/Q2U5H2 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/510516:AO090120000124 ^@ http://purl.uniprot.org/uniprot/Q2U6R7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ARPC4 family.|||Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.|||actin patch http://togogenome.org/gene/510516:AO090005000742 ^@ http://purl.uniprot.org/uniprot/Q2URP4 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/510516:AO090120000021 ^@ http://purl.uniprot.org/uniprot/Q2U705 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090023000065 ^@ http://purl.uniprot.org/uniprot/Q2UIG4 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/510516:AO090011000715 ^@ http://purl.uniprot.org/uniprot/Q2TZU7 ^@ Function|||Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family.|||Endo-1,4-mannanase, a crucial enzyme for depolymerization of seed galactomannans and wood galactoglucomannans. http://togogenome.org/gene/510516:AO090011000905 ^@ http://purl.uniprot.org/uniprot/Q2TZC9 ^@ Similarity ^@ Belongs to the EFG1/PHD1/stuA family. http://togogenome.org/gene/510516:AO090020000614 ^@ http://purl.uniprot.org/uniprot/Q2U3U5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090023000345 ^@ http://purl.uniprot.org/uniprot/Q2UHR3 ^@ Similarity ^@ Belongs to the transketolase family. http://togogenome.org/gene/510516:AO090009000148 ^@ http://purl.uniprot.org/uniprot/Q2UUW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/510516:AO090102000551 ^@ http://purl.uniprot.org/uniprot/Q2UA44 ^@ Similarity ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family. http://togogenome.org/gene/510516:AO090038000456 ^@ http://purl.uniprot.org/uniprot/Q2U2H3 ^@ Similarity ^@ Belongs to the UPF0507 family. http://togogenome.org/gene/510516:AO090001000135 ^@ http://purl.uniprot.org/uniprot/Q2UP30 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M35 family.|||Binds 1 zinc ion per subunit.|||Secreted|||Secreted metalloproteinase that allows assimilation of proteinaceous substrates. Shows high activities on basic nuclear substrates such as histone and protamine (By similarity). http://togogenome.org/gene/510516:AO090003000936 ^@ http://purl.uniprot.org/uniprot/Q2UK65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRN7/TAF1B family.|||nucleolus http://togogenome.org/gene/510516:AO090026000315 ^@ http://purl.uniprot.org/uniprot/Q2UF78 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090012000686 ^@ http://purl.uniprot.org/uniprot/Q2UC95 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/510516:AO090005001204 ^@ http://purl.uniprot.org/uniprot/Q2UQK9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prefoldin subunit beta family.|||Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/510516:AO090102000072 ^@ http://purl.uniprot.org/uniprot/Q2UB83 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 1 family.|||Binds 1 Ca(2+) ion per subunit.|||Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090003001025 ^@ http://purl.uniprot.org/uniprot/Q2UJY3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/510516:AO090026000708 ^@ http://purl.uniprot.org/uniprot/Q2UE97 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/510516:AO090009000412 ^@ http://purl.uniprot.org/uniprot/Q2UU90 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS19 family. http://togogenome.org/gene/510516:AO090005000409 ^@ http://purl.uniprot.org/uniprot/Q2USI8 ^@ Similarity ^@ Belongs to the SUN family. http://togogenome.org/gene/510516:AO090206000108 ^@ http://purl.uniprot.org/uniprot/Q2PIQ7 ^@ Similarity ^@ Belongs to the MTFP1 family. http://togogenome.org/gene/510516:AO090206000077 ^@ http://purl.uniprot.org/uniprot/Q2PIT0 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/510516:AO090023000787 ^@ http://purl.uniprot.org/uniprot/Q2UGM5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 61 family.|||Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM). The genes for catalytic modules and CBMs seem to have evolved separately and have been linked by gene fusion.|||Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds. Involved in the degradation of complex natural cellulosic substrates.|||Secreted http://togogenome.org/gene/510516:AO090012000493 ^@ http://purl.uniprot.org/uniprot/Q2UCQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||Membrane http://togogenome.org/gene/510516:AO090003001541 ^@ http://purl.uniprot.org/uniprot/Q2UIP0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003000938 ^@ http://purl.uniprot.org/uniprot/Q2UK63 ^@ PTM|||Similarity ^@ Belongs to the eIF-5A family.|||eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group. http://togogenome.org/gene/510516:AO090005000360 ^@ http://purl.uniprot.org/uniprot/Q2USN2 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. http://togogenome.org/gene/510516:AO090009000557 ^@ http://purl.uniprot.org/uniprot/Q2UTX2 ^@ Similarity ^@ Belongs to the malate synthase family. http://togogenome.org/gene/510516:AO090012000279 ^@ http://purl.uniprot.org/uniprot/Q2UD82 ^@ Similarity ^@ Belongs to the PheA/TfdB FAD monooxygenase family. http://togogenome.org/gene/510516:AO090005000166 ^@ http://purl.uniprot.org/uniprot/Q2UT42 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005001290 ^@ http://purl.uniprot.org/uniprot/Q2UQD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/510516:AO090011000453 ^@ http://purl.uniprot.org/uniprot/Q2U0G1 ^@ Function ^@ Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.|||Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate. http://togogenome.org/gene/510516:AO090003000186 ^@ http://purl.uniprot.org/uniprot/Q2UM12 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/510516:AO090701000495 ^@ http://purl.uniprot.org/uniprot/Q2U8B5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/510516:AO090003000017 ^@ http://purl.uniprot.org/uniprot/Q2UMF8 ^@ Similarity ^@ Belongs to the FAH family. http://togogenome.org/gene/510516:AO090102000067 ^@ http://purl.uniprot.org/uniprot/Q2UB87 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. http://togogenome.org/gene/510516:AO090026000435 ^@ http://purl.uniprot.org/uniprot/Q2UEX8 ^@ Similarity ^@ Belongs to the RMD1/sif2 family. http://togogenome.org/gene/510516:AO090023000615 ^@ http://purl.uniprot.org/uniprot/Q2UH24 ^@ Similarity ^@ Belongs to the tannase family. http://togogenome.org/gene/510516:AO090701000378 ^@ http://purl.uniprot.org/uniprot/Q2U8L8 ^@ Similarity ^@ Belongs to the DNA2/NAM7 helicase family. http://togogenome.org/gene/510516:AO090166000054 ^@ http://purl.uniprot.org/uniprot/Q2U9Q9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ThrE exporter (TC 2.A.79) family.|||Membrane http://togogenome.org/gene/510516:AO090120000106 ^@ http://purl.uniprot.org/uniprot/Q2U6T3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090010000483 ^@ http://purl.uniprot.org/uniprot/Q96VA4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. http://togogenome.org/gene/510516:AO090001000348 ^@ http://purl.uniprot.org/uniprot/Q2UNI8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 7 (cellulase C) family. http://togogenome.org/gene/510516:AO090102000108 ^@ http://purl.uniprot.org/uniprot/Q2UB51 ^@ Similarity ^@ Belongs to the gamma-glutamylcyclotransferase family. http://togogenome.org/gene/510516:AO090023000791 ^@ http://purl.uniprot.org/uniprot/Q2UGM1 ^@ Similarity ^@ Belongs to the protein prenyltransferase subunit alpha family. http://togogenome.org/gene/510516:AO090010000493 ^@ http://purl.uniprot.org/uniprot/P46076 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M35 family.|||Binds 1 zinc ion per subunit.|||Metalloprotease that shows high activities on basic nuclear substrates such as histone and protamine. http://togogenome.org/gene/510516:AO090001000378 ^@ http://purl.uniprot.org/uniprot/Q2UNG3 ^@ Similarity ^@ Belongs to the Tom22 family. http://togogenome.org/gene/510516:AO090020000134 ^@ http://purl.uniprot.org/uniprot/Q2U502 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the syntaxin family.|||Membrane http://togogenome.org/gene/510516:AO090003000654 ^@ http://purl.uniprot.org/uniprot/Q2UKV9 ^@ Similarity ^@ Belongs to the argonaute family. http://togogenome.org/gene/510516:AO090120000033 ^@ http://purl.uniprot.org/uniprot/Q2U6Z4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.|||Belongs to the NSE1 family.|||Component of the Smc5-Smc6 complex.|||Nucleus http://togogenome.org/gene/510516:AO090011000202 ^@ http://purl.uniprot.org/uniprot/Q2U124 ^@ Similarity ^@ Belongs to the globin family.|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. http://togogenome.org/gene/510516:AO090012000782 ^@ http://purl.uniprot.org/uniprot/Q2UC17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/510516:AO090001000559 ^@ http://purl.uniprot.org/uniprot/Q2UMZ7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090009000644 ^@ http://purl.uniprot.org/uniprot/Q2UTP9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterodimer of an alpha and a beta subunit.|||Mitochondrion|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/510516:AO090001000553 ^@ http://purl.uniprot.org/uniprot/Q2UN03 ^@ Similarity ^@ Belongs to the complex I 30 kDa subunit family. http://togogenome.org/gene/510516:AO090012000066 ^@ http://purl.uniprot.org/uniprot/Q2UDR3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090003001045 ^@ http://purl.uniprot.org/uniprot/Q2UJW6 ^@ Function ^@ Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway. http://togogenome.org/gene/510516:AO090102000493 ^@ http://purl.uniprot.org/uniprot/Q2UA91 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090011000937 ^@ http://purl.uniprot.org/uniprot/Q2TZA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.|||spindle http://togogenome.org/gene/510516:AO090020000588 ^@ http://purl.uniprot.org/uniprot/Q2U3W7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fungal hydrophobin family.|||cell wall http://togogenome.org/gene/510516:AO090003000462 ^@ http://purl.uniprot.org/uniprot/Q2ULC6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HEATR1/UTP10 family.|||Component of the ribosomal small subunit (SSU) processome.|||Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity).|||Membrane|||nucleolus http://togogenome.org/gene/510516:AO090038000348 ^@ http://purl.uniprot.org/uniprot/Q2U2R6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ORC1 family.|||Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.|||Nucleus|||ORC is composed of six subunits. http://togogenome.org/gene/510516:AO090005001532 ^@ http://purl.uniprot.org/uniprot/Q2UPS1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090005000892 ^@ http://purl.uniprot.org/uniprot/Q2URB7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit B family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm|||RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. http://togogenome.org/gene/510516:AO090701000727 ^@ http://purl.uniprot.org/uniprot/Q2U7S0 ^@ Similarity ^@ Belongs to the FUN14 family. http://togogenome.org/gene/510516:AO090023000645 ^@ http://purl.uniprot.org/uniprot/Q2UGZ9 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/510516:AO090003000808 ^@ http://purl.uniprot.org/uniprot/Q2UKH3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ERGIC family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Golgi apparatus membrane|||Plays a role in transport between endoplasmic reticulum and Golgi. http://togogenome.org/gene/510516:AO090003000618 ^@ http://purl.uniprot.org/uniprot/Q2UKY5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS7 family. http://togogenome.org/gene/510516:AO090020000007 ^@ http://purl.uniprot.org/uniprot/Q2U5A8 ^@ Caution|||Domain|||Function|||Miscellaneous|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetylated by esa1 to form H2AK4ac and H2AK7ac.|||Belongs to the histone H2A family.|||Chromosome|||Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||In contrast to vertebrates and insects, its C-terminus is not monoubiquitinated.|||Nucleus|||Phosphorylated to form H2AS128ph (gamma-H2A) in response to DNA double-strand breaks (DSBs) generated by exogenous genotoxic agents and by stalled replication forks. Phosphorylation is dependent on the DNA damage checkpoint kinases mec1/ATR and tel1/ATM, spreads on either side of a detected DSB site and may mark the surrounding chromatin for recruitment of proteins required for DNA damage signaling and repair. Gamma-H2A is removed from the DNA prior to the strand invasion-primer extension step of the repair process and subsequently dephosphorylated. Dephosphorylation is necessary for efficient recovery from the DNA damage checkpoint (By similarity).|||The [ST]-Q motif constitutes a recognition sequence for kinases from the PI3/PI4-kinase family.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.|||To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H2AK4ac = acetylated Lys-5; H2AK7ac = acetylated Lys-9; H2AS128ph = phosphorylated Ser-131. http://togogenome.org/gene/510516:AO090120000004 ^@ http://purl.uniprot.org/uniprot/Q2U721 ^@ Subcellular Location Annotation ^@ Membrane|||Vacuole membrane http://togogenome.org/gene/510516:AO090023000602 ^@ http://purl.uniprot.org/uniprot/Q2UH35 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S9B family.|||Extracellular dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.|||Secreted http://togogenome.org/gene/510516:AO090012000536 ^@ http://purl.uniprot.org/uniprot/Q2UCL7 ^@ Subcellular Location Annotation ^@ Membrane|||Vacuole membrane http://togogenome.org/gene/510516:AO090120000424 ^@ http://purl.uniprot.org/uniprot/Q2U611 ^@ Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. http://togogenome.org/gene/510516:AO090120000166 ^@ http://purl.uniprot.org/uniprot/Q2U6N4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000138 ^@ http://purl.uniprot.org/uniprot/Q2UT66 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090166000117 ^@ http://purl.uniprot.org/uniprot/Q2U9K7 ^@ Similarity ^@ Belongs to the amidase family. http://togogenome.org/gene/510516:AO090701000837 ^@ http://purl.uniprot.org/uniprot/Q2U7H5 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/510516:AO090005001522 ^@ http://purl.uniprot.org/uniprot/Q2UPT1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PPP phosphatase family. PP-Z subfamily.|||Cytoplasm http://togogenome.org/gene/510516:AO090038000308 ^@ http://purl.uniprot.org/uniprot/Q2U2V2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/510516:AO090001000413 ^@ http://purl.uniprot.org/uniprot/Q2UND2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL27 family. http://togogenome.org/gene/510516:AO090138000161 ^@ http://purl.uniprot.org/uniprot/Q2U1N4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090026000253 ^@ http://purl.uniprot.org/uniprot/Q2UFD1 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/510516:AO090001000512 ^@ http://purl.uniprot.org/uniprot/Q2UN43 ^@ Function|||Similarity ^@ Belongs to the adenylyl cyclase class-3 family.|||Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP. http://togogenome.org/gene/510516:AO090010000225 ^@ http://purl.uniprot.org/uniprot/Q2TXA1 ^@ Function|||Similarity ^@ Belongs to the eukaryotic initiation factor 4E family.|||Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. http://togogenome.org/gene/510516:AO090005001651 ^@ http://purl.uniprot.org/uniprot/Q2UPG5 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/510516:AO090011000590 ^@ http://purl.uniprot.org/uniprot/Q2U048 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/510516:AO090023000864 ^@ http://purl.uniprot.org/uniprot/Q2UGF2 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/510516:AO090102000391 ^@ http://purl.uniprot.org/uniprot/Q2UAG8 ^@ Similarity ^@ Belongs to the glycosyltransferase 15 family. http://togogenome.org/gene/510516:AO090005001223 ^@ http://purl.uniprot.org/uniprot/Q2UQJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DIF1/spd1 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/510516:AO090038000511 ^@ http://purl.uniprot.org/uniprot/Q2U2C3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.|||Membrane http://togogenome.org/gene/510516:AO090010000041 ^@ http://purl.uniprot.org/uniprot/Q2TXR3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/510516:AO090020000265 ^@ http://purl.uniprot.org/uniprot/Q2U4N7 ^@ Similarity|||Subunit ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Homotetramer. http://togogenome.org/gene/510516:AO090023000850 ^@ http://purl.uniprot.org/uniprot/Q2UGG5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrion-specific ribosomal protein mS23 family.|||Component of the mitochondrial small ribosomal subunit.|||Mitochondrion http://togogenome.org/gene/510516:AO090011000369 ^@ http://purl.uniprot.org/uniprot/Q2U0N2 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/510516:AO090011000743 ^@ http://purl.uniprot.org/uniprot/Q2TZS1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090023000884 ^@ http://purl.uniprot.org/uniprot/Q2UGD4 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/510516:AO090003000423 ^@ http://purl.uniprot.org/uniprot/Q2ULG2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for the ferulic acid decarboxylase FDC1. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Mitochondrion|||Oligomer. http://togogenome.org/gene/510516:AO090038000314 ^@ http://purl.uniprot.org/uniprot/Q2U2U6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/510516:AO090701000148 ^@ http://purl.uniprot.org/uniprot/Q2U969 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.|||Membrane http://togogenome.org/gene/510516:AO090010000616 ^@ http://purl.uniprot.org/uniprot/Q2TWC7 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/510516:AO090001000204 ^@ http://purl.uniprot.org/uniprot/Q2UNW7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090026000299 ^@ http://purl.uniprot.org/uniprot/Q2UF91 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/510516:AO090009000695 ^@ http://purl.uniprot.org/uniprot/Q2UTK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic release factor 1 family.|||Cytoplasm http://togogenome.org/gene/510516:AO090102000174 ^@ http://purl.uniprot.org/uniprot/Q2UAZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-B family.|||Nucleus http://togogenome.org/gene/510516:AO090009000427 ^@ http://purl.uniprot.org/uniprot/Q2UU75 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090102000557 ^@ http://purl.uniprot.org/uniprot/Q2UA39 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/510516:AO090011000777 ^@ http://purl.uniprot.org/uniprot/Q2TZP2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adaptor complexes small subunit family.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. http://togogenome.org/gene/510516:AO090009000242 ^@ http://purl.uniprot.org/uniprot/Q2UUN6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.|||Associates in the nucleolus with the 60S and pre-60S ribosomal subunits.|||Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.|||nucleolus http://togogenome.org/gene/510516:AO090005000813 ^@ http://purl.uniprot.org/uniprot/Q2URI6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CPSF4/YTH1 family.|||Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.|||Nucleus http://togogenome.org/gene/510516:AO090011000408 ^@ http://purl.uniprot.org/uniprot/Q2U0K2 ^@ Cofactor|||Disruption Phenotype|||Domain|||Function|||Induction|||Similarity ^@ Abolishes the production of heptelidic acid.|||Belongs to the terpene synthase family.|||Binds 3 Mg(2+) ions per subunit.|||Sesquiterpene cyclase; part of the gene cluster that mediates the biosynthesis of heptelidic acid (HA), a sesquiterpene lactone that acts as an inhibitor of glyceraldehyde-3-phosphatedehydrogenase (GAPDH) and a growth inhibitor of the salt-tolerant lactic acid bacteria in soy sauce brewing.|||The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+).|||The expression is positively regulated by the 2 cluster-specific transcription factors hepR and hepS. http://togogenome.org/gene/510516:AO090009000199 ^@ http://purl.uniprot.org/uniprot/Q2UUS2 ^@ Activity Regulation|||Similarity ^@ Activated by threonine and tyrosine phosphorylation.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/510516:AO090113000171 ^@ http://purl.uniprot.org/uniprot/Q2U5E9 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/510516:AO090701000645 ^@ http://purl.uniprot.org/uniprot/Q2U7Y8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090011000017 ^@ http://purl.uniprot.org/uniprot/Q2U1I4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090011000030 ^@ http://purl.uniprot.org/uniprot/Q2U1H3 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/510516:AO090103000332 ^@ http://purl.uniprot.org/uniprot/Q2TYA1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S10 family.|||Vacuolar carboxypeptidase involved in degradation of small peptides. Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity).|||Vacuole http://togogenome.org/gene/510516:AO090001000066 ^@ http://purl.uniprot.org/uniprot/Q2UP89 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tannase family.|||Homodimer.|||Involved in degradation of plant cell walls. Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans as well as the feruloyl-galactose and feruloyl-arabinose ester bonds in pectin.|||Secreted|||The calcium ion seen in the crystal structure is located far from the active site and appears to have a role in stabilization of the lid domain. http://togogenome.org/gene/510516:AO090701000012 ^@ http://purl.uniprot.org/uniprot/Q2U9J0 ^@ Similarity ^@ Belongs to the TRAPP small subunits family. BET3 subfamily. http://togogenome.org/gene/510516:AO090012000627 ^@ http://purl.uniprot.org/uniprot/Q2UCE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TUBGCP family.|||microtubule organizing center http://togogenome.org/gene/510516:AO090120000293 ^@ http://purl.uniprot.org/uniprot/Q2U6C7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.|||Belongs to the peptidase S16 family.|||Peroxisome matrix http://togogenome.org/gene/510516:AO090012000916 ^@ http://purl.uniprot.org/uniprot/Q2UBP8 ^@ Subcellular Location Annotation ^@ Membrane|||Vacuole membrane http://togogenome.org/gene/510516:AO090012000933 ^@ http://purl.uniprot.org/uniprot/Q2UBN1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090103000011 ^@ http://purl.uniprot.org/uniprot/Q2TZ24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Nucleus http://togogenome.org/gene/510516:AO090005000561 ^@ http://purl.uniprot.org/uniprot/Q2US57 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 76 family. http://togogenome.org/gene/510516:AO090011000412 ^@ http://purl.uniprot.org/uniprot/Q2U0J9 ^@ Disruption Phenotype|||Function|||Similarity ^@ Abolishes the production of heptelidic acid.|||Belongs to the cytochrome P450 family.|||Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of heptelidic acid (HA), a sesquiterpene lactone that acts as an inhibitor of glyceraldehyde-3-phosphatedehydrogenase (GAPDH) and a growth inhibitor of the salt-tolerant lactic acid bacteria in soy sauce brewing. http://togogenome.org/gene/510516:AO090005000050 ^@ http://purl.uniprot.org/uniprot/Q2UTE5 ^@ Similarity ^@ Belongs to the amino acid/polyamine transporter 2 family. http://togogenome.org/gene/510516:AO090003001259 ^@ http://purl.uniprot.org/uniprot/Q2UJD7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090026000181 ^@ http://purl.uniprot.org/uniprot/Q2UFJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EBP family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/510516:AO090003001036 ^@ http://purl.uniprot.org/uniprot/P12547 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S8 family.|||Expression is controlled by the prtT transcription factor.|||Secreted|||Secreted alkaline protease that allows assimilation of proteinaceous substrates. http://togogenome.org/gene/510516:AO090038000009 ^@ http://purl.uniprot.org/uniprot/Q2U3J6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/510516:AO090026000396 ^@ http://purl.uniprot.org/uniprot/Q2UF09 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090011000740 ^@ http://purl.uniprot.org/uniprot/Q2TZS4 ^@ Similarity ^@ Belongs to the paxB family. http://togogenome.org/gene/510516:AO090005000773 ^@ http://purl.uniprot.org/uniprot/Q2URM0 ^@ Subcellular Location Annotation ^@ Nucleus|||kinetochore http://togogenome.org/gene/510516:AO090124000079 ^@ http://purl.uniprot.org/uniprot/Q2U738 ^@ Function ^@ The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. http://togogenome.org/gene/510516:AO090026000433 ^@ http://purl.uniprot.org/uniprot/Q2UEY0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090020000696 ^@ http://purl.uniprot.org/uniprot/Q2U3M6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090023000806 ^@ http://purl.uniprot.org/uniprot/Q2UGK6 ^@ Similarity ^@ Belongs to the PurH family. http://togogenome.org/gene/510516:AO090005000472 ^@ http://purl.uniprot.org/uniprot/Q2USD5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 3 family.|||Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.|||Secreted http://togogenome.org/gene/510516:AO090020000057 ^@ http://purl.uniprot.org/uniprot/Q2U562 ^@ Similarity ^@ Belongs to the OSBP family. http://togogenome.org/gene/510516:AO090023000756 ^@ http://purl.uniprot.org/uniprot/Q2UGQ4 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/510516:AO090026000639 ^@ http://purl.uniprot.org/uniprot/Q2UEF4 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/510516:AO090020000613 ^@ http://purl.uniprot.org/uniprot/Q2U3U6 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/510516:AO090003001090 ^@ http://purl.uniprot.org/uniprot/Q2UJS9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.|||Membrane http://togogenome.org/gene/510516:AO090005001031 ^@ http://purl.uniprot.org/uniprot/Q2UR01 ^@ Similarity ^@ Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family. http://togogenome.org/gene/510516:AO090011000649 ^@ http://purl.uniprot.org/uniprot/Q2U001 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/510516:AO090206000080 ^@ http://purl.uniprot.org/uniprot/Q2PIS7 ^@ Similarity ^@ Belongs to the amidase family. http://togogenome.org/gene/510516:AO090026000569 ^@ http://purl.uniprot.org/uniprot/Q2UEL6 ^@ Similarity ^@ Belongs to the ketopantoate reductase family. http://togogenome.org/gene/510516:AO090026000515 ^@ http://purl.uniprot.org/uniprot/Q2UER3 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/510516:AO090011000358 ^@ http://purl.uniprot.org/uniprot/Q2U0P2 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/510516:AO090009000522 ^@ http://purl.uniprot.org/uniprot/Q2UU00 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090701000398 ^@ http://purl.uniprot.org/uniprot/Q2U8K5 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase II family. http://togogenome.org/gene/510516:AO090038000254 ^@ http://purl.uniprot.org/uniprot/Q2U2Z8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.|||Golgi apparatus|||Membrane http://togogenome.org/gene/510516:AO090001000522 ^@ http://purl.uniprot.org/uniprot/Q2UN34 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family. http://togogenome.org/gene/510516:AO090102000556 ^@ http://purl.uniprot.org/uniprot/Q2UA40 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Heterodimer of a catalytic subunit and an accessory subunit.|||Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). http://togogenome.org/gene/510516:AO090005000074 ^@ http://purl.uniprot.org/uniprot/Q2UTC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090701000090 ^@ http://purl.uniprot.org/uniprot/Q2U9C0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/510516:AO090011000414 ^@ http://purl.uniprot.org/uniprot/Q2U0J7 ^@ Disruption Phenotype|||Function|||Similarity|||Subunit ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Does not affect the biosynthesis of heptelidic acid.|||Glyceraldehyde-3-phosphate dehydrogenase; part of the gene cluster that mediates the biosynthesis of heptelidic acid (HA), a sesquiterpene lactone that acts as an inhibitor of glyceraldehyde-3-phosphatedehydrogenase (GAPDH) and a growth inhibitor of the salt-tolerant lactic acid bacteria in soy sauce brewing (PubMed:30466366). The GAPDPH hepG/gdpB shows much higher resistance to HA than the GAPDH gpdA located outside of the cluster, but it does not seem to act in self-resistance (PubMed:30466366).|||Homotetramer. http://togogenome.org/gene/510516:AO090026000225 ^@ http://purl.uniprot.org/uniprot/Q2UFF8 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/510516:AO090003000354 ^@ http://purl.uniprot.org/uniprot/Q2ULM2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M28 family. M28A subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Extracellular aminopeptidase that releases a wide variety of amino acids from natural peptides.|||Monomer.|||Secreted http://togogenome.org/gene/510516:AO090102000515 ^@ http://purl.uniprot.org/uniprot/Q2UA72 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 5'-3' exonuclease family.|||Cytoplasm|||Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. http://togogenome.org/gene/510516:AO090005001434 ^@ http://purl.uniprot.org/uniprot/Q2UQ09 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090003001255 ^@ http://purl.uniprot.org/uniprot/Q2UJE0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL12 family. http://togogenome.org/gene/510516:AO090012001002 ^@ http://purl.uniprot.org/uniprot/Q2UBH2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090120000230 ^@ http://purl.uniprot.org/uniprot/Q2U6H9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003000971 ^@ http://purl.uniprot.org/uniprot/Q2UK34 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090701000709 ^@ http://purl.uniprot.org/uniprot/Q2U7T4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ANKZF1/VMS1 family.|||Cytoplasm http://togogenome.org/gene/510516:AO090038000383 ^@ http://purl.uniprot.org/uniprot/Q2U2N6 ^@ Function|||Subcellular Location Annotation ^@ RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.|||nucleolus http://togogenome.org/gene/510516:AO090012000051 ^@ http://purl.uniprot.org/uniprot/Q2UDS4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090012000264 ^@ http://purl.uniprot.org/uniprot/Q2UD96 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/510516:AO090010000218 ^@ http://purl.uniprot.org/uniprot/Q2TXA8 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/510516:AO090009000288 ^@ http://purl.uniprot.org/uniprot/Q2UUJ8 ^@ Similarity ^@ Belongs to the flavin monoamine oxidase family. http://togogenome.org/gene/510516:AO090005001001 ^@ http://purl.uniprot.org/uniprot/Q2UR24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.|||Nucleus http://togogenome.org/gene/510516:AO090026000518 ^@ http://purl.uniprot.org/uniprot/Q2UER0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090010000176 ^@ http://purl.uniprot.org/uniprot/Q2TXE7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090020000530 ^@ http://purl.uniprot.org/uniprot/Q2U417 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EMC1 family.|||Component of the ER membrane protein complex (EMC).|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/510516:AO090020000056 ^@ http://purl.uniprot.org/uniprot/Q2U563 ^@ Similarity ^@ Belongs to the IFRD family. http://togogenome.org/gene/510516:AO090003000414 ^@ http://purl.uniprot.org/uniprot/Q2ULH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/510516:AO090701000463 ^@ http://purl.uniprot.org/uniprot/Q2U8E2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090011000894 ^@ http://purl.uniprot.org/uniprot/Q2TZD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/510516:AO090012000181 ^@ http://purl.uniprot.org/uniprot/Q2UDG5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090023000023 ^@ http://purl.uniprot.org/uniprot/Q2UIK3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090701000448 ^@ http://purl.uniprot.org/uniprot/Q2U8F7 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/510516:AO090005000844 ^@ http://purl.uniprot.org/uniprot/Q2URF9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090026000003 ^@ http://purl.uniprot.org/uniprot/Q2UG11 ^@ Function|||Similarity ^@ Belongs to the beta-cyclopiazonate dehydrogenase family.|||Beta-cyclopiazonate dehydrogenase involved in the synthesis of the fungal neurotoxin alpha-cyclopiazonic acid (CPA). CpaO carries out the dehydrogenation of beta-CPA to yield an unstable enimine product, which is captured by intramolecular cyclization to create the pentacyclic fused scaffold of alpha-cyclopiazonate. http://togogenome.org/gene/510516:AO090011000717 ^@ http://purl.uniprot.org/uniprot/Q2TZU5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DP1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/510516:AO090003001431 ^@ http://purl.uniprot.org/uniprot/Q2UIY0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/510516:AO090012000602 ^@ http://purl.uniprot.org/uniprot/Q2UCG2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000392 ^@ http://purl.uniprot.org/uniprot/Q2USK4 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/510516:AO090020000138 ^@ http://purl.uniprot.org/uniprot/Q2U4Z8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/510516:AO090020000338 ^@ http://purl.uniprot.org/uniprot/Q2U4H8 ^@ Similarity ^@ Belongs to the proteasome subunit p55 family. http://togogenome.org/gene/510516:AO090003000484 ^@ http://purl.uniprot.org/uniprot/Q2ULA5 ^@ Cofactor|||Function|||Similarity ^@ Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.|||Belongs to the tRNA(His) guanylyltransferase family.|||Binds 2 magnesium ions per subunit. http://togogenome.org/gene/510516:AO090010000444 ^@ http://purl.uniprot.org/uniprot/Q9HGZ0 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/510516:AO090011000613 ^@ http://purl.uniprot.org/uniprot/Q2U027 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the myo-inositol oxygenase family.|||Binds 2 iron ions per subunit.|||Cytoplasm http://togogenome.org/gene/510516:AO090020000622 ^@ http://purl.uniprot.org/uniprot/Q2U3T8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the protein kinase superfamily. BUD32 family.|||Component of the EKC/KEOPS complex composed of at least bud32, cgi121, gon7, kae1 and pcc1; the whole complex dimerizes.|||Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.|||Cytoplasm|||Nucleus|||This protein is considered an atypical serine/threonine kinase, because it lacks the conventional structural elements necessary for the substrate recognition as well as a lysine residue that in all other serine/threonine kinases participates in the catalytic event (By similarity). BUD32 has protein kinase activity in vitro, but in the context of the EKC/KEOPS complex, the catalytic subunit KAE1 switches the activity of BUD32 from kinase into ATPase (By similarity).|||telomere http://togogenome.org/gene/510516:AO090026000580 ^@ http://purl.uniprot.org/uniprot/Q2UEK6 ^@ Disruption Phenotype|||Function|||Induction|||Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Expression is regulated by the secondary metabolite regulator cclA.|||Short chain dehydrogenase/reductase; part of the gene cluster that mediates the biosynthesis of astellolides, drimane-type sesquiterpene esters that show antimicrobial, anti-inflammatory, and anti-tumor activities (PubMed:27628599). The first step in astellolide biosynthesis is performed by the sesquiterpene cyclase astC that catalyzes the formation of drimanyl pyrophosphate from farnesyl pyrophosphate (PubMed:27628599). Drimanyl pyrophosphate is then dephosphorylated by the sesquiterpene phosphatase astI to produce drimanyl monophosphate which is further dephosphorylated to drim-8-ene-11-ol by atsK (PubMed:27628599). Drim-8-ene-11-ol is converted to confertifolin, probably by the cytochrome P450 monooxygenase astD and/or the dehydrogenase astE (PubMed:27628599). The cytochrome P450 monooxygenases astB, astF and astJ then hydroxylate confertifolin at C6, C14, or C15 to form trihydroxy confertifolin (PubMed:27628599). The nonribosomal peptide synthetase astA catalyzes ester bond formation between trihydroxy contifolin and benzoic acid (BA) or 4-hydroxy benzoic acid (4HBA), leading to the formation of dideacetyl astellolides A and B, respectively (PubMed:27628599). Finally, the O-acetyltransferase astG converts dideacetyl astellolides A and B into deacetyl astellolides A and B (PubMed:27628599).|||Significantly reduces the production of deacetyl astellolides A and B. http://togogenome.org/gene/510516:AO090120000224 ^@ http://purl.uniprot.org/uniprot/Q2U6I3 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/510516:AO090011000204 ^@ http://purl.uniprot.org/uniprot/Q2U122 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090020000304 ^@ http://purl.uniprot.org/uniprot/Q2U4K5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRM CPSF6/7 family.|||Nucleus http://togogenome.org/gene/510516:AO090011000064 ^@ http://purl.uniprot.org/uniprot/Q2U1E3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090102000606 ^@ http://purl.uniprot.org/uniprot/Q2U9Z4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/510516:AO090003001089 ^@ http://purl.uniprot.org/uniprot/Q2UJT0 ^@ Similarity ^@ Belongs to the FBPase class 1 family. http://togogenome.org/gene/510516:AO090010000229 ^@ http://purl.uniprot.org/uniprot/Q2TX98 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. http://togogenome.org/gene/510516:AO090011000024 ^@ http://purl.uniprot.org/uniprot/Q2U1H8 ^@ Similarity ^@ Belongs to the MSOX/MTOX family. http://togogenome.org/gene/510516:AO090012000415 ^@ http://purl.uniprot.org/uniprot/Q2UCW9 ^@ Similarity ^@ Belongs to the gamma-BBH/TMLD family. http://togogenome.org/gene/510516:AO090023000509 ^@ http://purl.uniprot.org/uniprot/Q2UHB8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003000693 ^@ http://purl.uniprot.org/uniprot/Q2UKS5 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/510516:AO090026000670 ^@ http://purl.uniprot.org/uniprot/Q2UEC9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TFB4 family.|||Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.|||Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.|||Nucleus http://togogenome.org/gene/510516:AO090020000048 ^@ http://purl.uniprot.org/uniprot/Q2U570 ^@ Similarity ^@ Belongs to the isochorismatase family. http://togogenome.org/gene/510516:AO090023000762 ^@ http://purl.uniprot.org/uniprot/Q2UGP8 ^@ Function|||Similarity ^@ Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.|||Belongs to the NMT family. http://togogenome.org/gene/510516:AO090020000047 ^@ http://purl.uniprot.org/uniprot/Q2U571 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090701000031 ^@ http://purl.uniprot.org/uniprot/Q2U9H3 ^@ Function|||Similarity ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37. http://togogenome.org/gene/510516:AO090102000368 ^@ http://purl.uniprot.org/uniprot/Q2UAI8 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/510516:AO090701000880 ^@ http://purl.uniprot.org/uniprot/Q2U7D5 ^@ Similarity ^@ Belongs to the carotenoid oxygenase family. http://togogenome.org/gene/510516:AO090001000425 ^@ http://purl.uniprot.org/uniprot/Q2UNC0 ^@ Similarity ^@ Belongs to the CoA-transferase III family. http://togogenome.org/gene/510516:AO090003000382 ^@ http://purl.uniprot.org/uniprot/Q2ULJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SDE2 family.|||Nucleus http://togogenome.org/gene/510516:AO090023000796 ^@ http://purl.uniprot.org/uniprot/Q2UGL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.|||Mediates the uptake of pyruvate into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090003001087 ^@ http://purl.uniprot.org/uniprot/Q2UJT1 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/510516:AO090010000710 ^@ http://purl.uniprot.org/uniprot/Q2TW45 ^@ Similarity|||Subunit ^@ Belongs to the methylaspartate ammonia-lyase family.|||Homodimer. http://togogenome.org/gene/510516:AO090003000839 ^@ http://purl.uniprot.org/uniprot/Q2UKE6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PLPL family.|||Membrane|||Probable lipid hydrolase. http://togogenome.org/gene/510516:AO090023000893 ^@ http://purl.uniprot.org/uniprot/Q2UGC5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.|||Delta(4)-fatty-acid desaturase which introduces a double bond at the 4-position in the long-chain base (LCB) of ceramides.|||Membrane http://togogenome.org/gene/510516:AO090120000149 ^@ http://purl.uniprot.org/uniprot/Q2U6P7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 also plays a role in pre-mRNA splicing and spliceosome assembly. May be involved in rDNA and telomeric silencing, and maintenance of genome integrity (By similarity).|||Belongs to the DEAD box helicase family. DECD subfamily.|||Nucleus|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/510516:AO090005000302 ^@ http://purl.uniprot.org/uniprot/Q2UST4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090701000425 ^@ http://purl.uniprot.org/uniprot/Q2U8H9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090023000980 ^@ http://purl.uniprot.org/uniprot/Q2UG48 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M49 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/510516:AO090023000571 ^@ http://purl.uniprot.org/uniprot/Q2UH61 ^@ Function|||Similarity ^@ Belongs to the GMC oxidoreductase family.|||Long-chain fatty alcohol oxidase involved in the omega-oxidation pathway of lipid degradation. http://togogenome.org/gene/510516:AO090026000749 ^@ http://purl.uniprot.org/uniprot/Q2UE62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/510516:AO090020000522 ^@ http://purl.uniprot.org/uniprot/Q2U424 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LCL3 family.|||Cytoplasm|||Membrane|||Mitochondrion http://togogenome.org/gene/510516:AO090038000552 ^@ http://purl.uniprot.org/uniprot/Q2U293 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 28 family.|||Pectinolytic enzymes consist of four classes of enzymes: pectine lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Hydrolyzes alpha-D-galacturonopyranosyl-(1,2)-alpha-L-rhamnopyranosyl linkages in the backbone of the hairy regions of pectins (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090001000697 ^@ http://purl.uniprot.org/uniprot/Q2UMM8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic GTase family.|||Heterodimer.|||Nucleus|||Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate. http://togogenome.org/gene/510516:AO090103000456 ^@ http://purl.uniprot.org/uniprot/Q2TXY9 ^@ Similarity ^@ Belongs to the FMO family. http://togogenome.org/gene/510516:AO090023000476 ^@ http://purl.uniprot.org/uniprot/Q2UHE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tom20 family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/510516:AO090001000544 ^@ http://purl.uniprot.org/uniprot/Q2UN12 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 3 family.|||Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090020000298 ^@ http://purl.uniprot.org/uniprot/Q2U4K9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL21 family. http://togogenome.org/gene/510516:AO090113000110 ^@ http://purl.uniprot.org/uniprot/Q2U5K2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the anamorsin family.|||Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex cfd1-nbp35. Electrons are transferred to dre2 from NADPH via the FAD- and FMN-containing protein tah18. Tah18-dre2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit rnr2.|||Cytoplasm|||Mitochondrion intermembrane space|||Monomer. Interacts with tah18. Interacts with mia40.|||The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.|||The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.|||The twin Cx2C motifs are involved in the recognition by the mitochondrial mia40-erv1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space. http://togogenome.org/gene/510516:AO090003001385 ^@ http://purl.uniprot.org/uniprot/Q2UJ22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.|||Membrane http://togogenome.org/gene/510516:AO090120000026 ^@ http://purl.uniprot.org/uniprot/Q9HFA4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 11 (cellulase G) family.|||Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.|||Secreted|||The promoter contains two 5'-GGCTAAA-3' sequences identified as binding sites for the xylanolytic transcriptional activator xlnR. http://togogenome.org/gene/510516:AO090005001561 ^@ http://purl.uniprot.org/uniprot/Q2UPP6 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/510516:AO090003001230 ^@ http://purl.uniprot.org/uniprot/Q2UJG2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the clathrin light chain family.|||Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.|||Cytoplasmic vesicle membrane|||coated pit http://togogenome.org/gene/510516:AO090012000613 ^@ http://purl.uniprot.org/uniprot/Q2UCF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uL18 family.|||Cytoplasm http://togogenome.org/gene/510516:AO090020000414 ^@ http://purl.uniprot.org/uniprot/Q2U4B2 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/510516:AO090005000221 ^@ http://purl.uniprot.org/uniprot/Q2UT02 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003000666 ^@ http://purl.uniprot.org/uniprot/Q2UKU9 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/510516:AO090012000577 ^@ http://purl.uniprot.org/uniprot/Q2UCI4 ^@ Similarity ^@ Belongs to the G-alpha family. G(q) subfamily. http://togogenome.org/gene/510516:AO090120000261 ^@ http://purl.uniprot.org/uniprot/Q2U6F2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/510516:AO090005001028 ^@ http://purl.uniprot.org/uniprot/Q2UR03 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003000974 ^@ http://purl.uniprot.org/uniprot/Q2UK31 ^@ Similarity ^@ Belongs to the TMCO4 family. http://togogenome.org/gene/510516:AO090011000113 ^@ http://purl.uniprot.org/uniprot/Q2U199 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cutinase family.|||Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants (By similarity). Degrades cutin, a macromolecule that forms the structure of the plant cuticle (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090701000400 ^@ http://purl.uniprot.org/uniprot/Q2U8K3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/510516:AO090005001516 ^@ http://purl.uniprot.org/uniprot/Q2UPT6 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/510516:AO090001000098 ^@ http://purl.uniprot.org/uniprot/Q2UP63 ^@ Similarity ^@ Belongs to the invertebrate defensin family. http://togogenome.org/gene/510516:AO090026000141 ^@ http://purl.uniprot.org/uniprot/Q2UFN0 ^@ Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homodimer. http://togogenome.org/gene/510516:AO090011000503 ^@ http://purl.uniprot.org/uniprot/Q2U0B8 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/510516:AO090005000495 ^@ http://purl.uniprot.org/uniprot/Q2USB4 ^@ Similarity ^@ Belongs to the CoA-transferase III family. http://togogenome.org/gene/510516:AO090005000064 ^@ http://purl.uniprot.org/uniprot/Q2UTD2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/510516:AO090020000387 ^@ http://purl.uniprot.org/uniprot/Q2U4D4 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. http://togogenome.org/gene/510516:AO090009000395 ^@ http://purl.uniprot.org/uniprot/Q2UUA2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS12 family. http://togogenome.org/gene/510516:AO090001000304 ^@ http://purl.uniprot.org/uniprot/Q2UNM5 ^@ Function|||Similarity|||Subunit ^@ Associates with the respiratory chain complex III/complex IV supercomplex.|||Belongs to the RCF1 family.|||Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes. http://togogenome.org/gene/510516:AO090023000574 ^@ http://purl.uniprot.org/uniprot/Q2UH58 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/510516:AO090012000956 ^@ http://purl.uniprot.org/uniprot/Q2UBL0 ^@ Similarity ^@ Belongs to the fructosamine kinase family. http://togogenome.org/gene/510516:AO090020000537 ^@ http://purl.uniprot.org/uniprot/Q2U411 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/510516:AO090012000468 ^@ http://purl.uniprot.org/uniprot/Q2UCS3 ^@ Similarity ^@ Belongs to the IST1 family. http://togogenome.org/gene/510516:AO090012001014 ^@ http://purl.uniprot.org/uniprot/Q2UBG1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090011000045 ^@ http://purl.uniprot.org/uniprot/Q2U1F8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090011000351 ^@ http://purl.uniprot.org/uniprot/Q2U0P9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GcvP family.|||Mitochondrion|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/510516:AO090701000193 ^@ http://purl.uniprot.org/uniprot/Q2U931 ^@ Cofactor|||Similarity ^@ Belongs to the eukaryotic GSH synthase family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/510516:AO090138000066 ^@ http://purl.uniprot.org/uniprot/Q2U1W8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 28 family.|||Secreted http://togogenome.org/gene/510516:AO090020000516 ^@ http://purl.uniprot.org/uniprot/Q2U429 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/510516:AO090038000038 ^@ http://purl.uniprot.org/uniprot/Q2U3H2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090026000766 ^@ http://purl.uniprot.org/uniprot/Q2UE45 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/510516:AO090003000724 ^@ http://purl.uniprot.org/uniprot/Q2UKP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CSC1 (TC 1.A.17) family.|||Membrane http://togogenome.org/gene/510516:AO090003000104 ^@ http://purl.uniprot.org/uniprot/Q2UM80 ^@ Similarity ^@ Belongs to the GINS4/SLD5 family. http://togogenome.org/gene/510516:AO090023000287 ^@ http://purl.uniprot.org/uniprot/Q2UHW4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090010000488 ^@ http://purl.uniprot.org/uniprot/Q2TWN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090023000453 ^@ http://purl.uniprot.org/uniprot/Q2UHG7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090020000085 ^@ http://purl.uniprot.org/uniprot/Q2U540 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/510516:AO090023000692 ^@ http://purl.uniprot.org/uniprot/Q9C1T1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the histidine acid phosphatase family.|||Catalyzes the hydrolysis of inorganic orthophosphate from phytate.|||Secreted http://togogenome.org/gene/510516:AO090020000657 ^@ http://purl.uniprot.org/uniprot/Q2U3R0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090023000874 ^@ http://purl.uniprot.org/uniprot/Q2UGE4 ^@ Similarity ^@ In the C-terminal section; belongs to the TrpB family.|||In the N-terminal section; belongs to the TrpA family. http://togogenome.org/gene/510516:AO090023001000 ^@ http://purl.uniprot.org/uniprot/Q2UG30 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090005000227 ^@ http://purl.uniprot.org/uniprot/Q2USZ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane|||Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. http://togogenome.org/gene/510516:AO090010000407 ^@ http://purl.uniprot.org/uniprot/Q2TWU8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090026000392 ^@ http://purl.uniprot.org/uniprot/Q2UF13 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/510516:AO090001000604 ^@ http://purl.uniprot.org/uniprot/Q2UMV7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family.|||Cell membrane|||Glucosidase involved in the degradation of cellulosic biomass. Active on lichenan (By similarity). http://togogenome.org/gene/510516:AO090012000189 ^@ http://purl.uniprot.org/uniprot/Q2UDF7 ^@ Similarity ^@ Belongs to the importin alpha family. http://togogenome.org/gene/510516:AO090023000732 ^@ http://purl.uniprot.org/uniprot/Q2UGS2 ^@ Similarity ^@ Belongs to the peptidase M28 family. http://togogenome.org/gene/510516:AO090038000282 ^@ http://purl.uniprot.org/uniprot/Q2U2X4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GLE1 family.|||nuclear pore complex http://togogenome.org/gene/510516:AO090010000484 ^@ http://purl.uniprot.org/uniprot/Q2TWN8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 28 family.|||Pectinolytic enzymes consist of four classes of enzymes: pectine lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Hydrolyzes alpha-D-galacturonopyranosyl-(1,2)-alpha-L-rhamnopyranosyl linkages in the backbone of the hairy regions of pectins (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090138000036 ^@ http://purl.uniprot.org/uniprot/Q2U1Z6 ^@ Function|||Similarity ^@ Belongs to the choline monooxygenase family.|||Catalyzes the first step of the osmoprotectant glycine betaine synthesis. http://togogenome.org/gene/510516:AO090026000425 ^@ http://purl.uniprot.org/uniprot/Q2UEY7 ^@ Similarity ^@ Belongs to the SIN1 family. http://togogenome.org/gene/510516:AO090003000529 ^@ http://purl.uniprot.org/uniprot/Q2UL67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CCC1 family.|||Membrane http://togogenome.org/gene/510516:AO090003001237 ^@ http://purl.uniprot.org/uniprot/Q2UJF6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090023000669 ^@ http://purl.uniprot.org/uniprot/Q2UGX8 ^@ Subcellular Location Annotation ^@ Nucleus|||telomere http://togogenome.org/gene/510516:AO090003000789 ^@ http://purl.uniprot.org/uniprot/Q2UKI8 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily. http://togogenome.org/gene/510516:AO090003000034 ^@ http://purl.uniprot.org/uniprot/Q2UME2 ^@ Similarity ^@ Belongs to the chloroperoxidase family. http://togogenome.org/gene/510516:AO090009000653 ^@ http://purl.uniprot.org/uniprot/Q5KU00 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SKP1 family.|||Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.|||Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Controls sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor (By similarity). http://togogenome.org/gene/510516:AO090003000056 ^@ http://purl.uniprot.org/uniprot/Q2UMC3 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/510516:AO090012000715 ^@ http://purl.uniprot.org/uniprot/Q2UC70 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/510516:AO090009000638 ^@ http://purl.uniprot.org/uniprot/Q2UTQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STE12 transcription factor family.|||Nucleus http://togogenome.org/gene/510516:AO090138000031 ^@ http://purl.uniprot.org/uniprot/Q2U201 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090020000309 ^@ http://purl.uniprot.org/uniprot/Q2U4K2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sorting nexin family.|||Cytoplasm|||Golgi apparatus membrane|||Prevacuolar compartment membrane|||Required for retention of late Golgi membrane proteins. Component of the retrieval machinery that functions by direct interaction with the cytosolic tails of certain TGN membrane proteins during the sorting/budding process at the prevacuolar compartment. Binds phosphatidylinositol 3-phosphate (PtdIns(P3)) (By similarity).|||The PX domain binds phosphatidylinositol 3-phosphate which is necessary for peripheral membrane localization. http://togogenome.org/gene/510516:AO090005000029 ^@ http://purl.uniprot.org/uniprot/P52956 ^@ Activity Regulation|||Biotechnology|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cutinase family.|||Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants (PubMed:19810726, PubMed:15968570). Degrades cutin, a macromolecule that forms the structure of the plant cuticle (PubMed:19810726, PubMed:15968570).|||Competitively inhibited by the carboxylic acids butyric acid, valeric acid and hexanoic acid (PubMed:15968570). Competitively inhibited by the dicarboxylic acid succinic acid (PubMed:15968570). Competitively inhibited by the alcohols propan-1-ol, butan-1-ol, hexan-1-ol, octan-1-ol, and butane-1,4-diol (PubMed:15968570).|||Secreted|||This enzyme enables the fungus to utilize the biodegradable plastics poly(butylene succinate) (PBS) and poly(butylene succinate-co-butylene adipate) (PBSA) as sole carbon source and could therefore be used in plastic recycling. http://togogenome.org/gene/510516:AO090026000469 ^@ http://purl.uniprot.org/uniprot/Q2UEV2 ^@ Similarity ^@ Belongs to the SAP30 family. http://togogenome.org/gene/510516:AO090003000962 ^@ http://purl.uniprot.org/uniprot/Q06157 ^@ Function|||Induction|||Subcellular Location Annotation ^@ By omega amino acids.|||Nucleus|||Positively regulates the expression of genes involved in the catabolism of certain amides, omega amino acids, and lactams. http://togogenome.org/gene/510516:AO090120000144 ^@ http://purl.uniprot.org/uniprot/Q2U6Q0 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/510516:AO090003000927 ^@ http://purl.uniprot.org/uniprot/Q2UK72 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyadenylate-binding protein type-1 family.|||Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and regulates mRNA decay through translation termination-coupled poly(A) shortening, probably mediated by PAN (By similarity).|||Cytoplasm|||Nucleus http://togogenome.org/gene/510516:AO090701000729 ^@ http://purl.uniprot.org/uniprot/Q2U7R8 ^@ Function|||Miscellaneous|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.|||Heterodimer of an alpha and a beta chain.|||Mitochondrion matrix|||The alpha and beta chains are autoproteolytically processed from a single precursor protein within the mitochondrion.|||This protein may be expected to contain an N-terminal transit peptide but none has been predicted. http://togogenome.org/gene/510516:AO090020000521 ^@ http://purl.uniprot.org/uniprot/Q877B5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Cu-Zn superoxide dismutase family.|||Binds 1 copper ion per subunit.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems.|||Homodimer. http://togogenome.org/gene/510516:AO090012000155 ^@ http://purl.uniprot.org/uniprot/Q2UDJ0 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/510516:AO090001000428 ^@ http://purl.uniprot.org/uniprot/Q2UNB7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent rRNA helicase required for pre-ribosomal RNA processing. Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA.|||Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.|||Interacts with the SSU processome.|||Nucleus|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/510516:AO090001000698 ^@ http://purl.uniprot.org/uniprot/Q2UMM7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OST1 family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/510516:AO090003000285 ^@ http://purl.uniprot.org/uniprot/Q2ULS7 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. http://togogenome.org/gene/510516:AO090026000022 ^@ http://purl.uniprot.org/uniprot/Q2UFZ3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090701000032 ^@ http://purl.uniprot.org/uniprot/Q2U9H2 ^@ Similarity ^@ Belongs to the GET4 family. http://togogenome.org/gene/510516:AO090001000751 ^@ http://purl.uniprot.org/uniprot/Q2UMH6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.|||Belongs to the replication factor A protein 1 family.|||Component of the heterotrimeric canonical replication protein A complex (RPA).|||Nucleus http://togogenome.org/gene/510516:AO090120000109 ^@ http://purl.uniprot.org/uniprot/Q2U6T0 ^@ Similarity ^@ Belongs to the hexokinase family. http://togogenome.org/gene/510516:AO090023000312 ^@ http://purl.uniprot.org/uniprot/Q2UHU1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/510516:AO090701000014 ^@ http://purl.uniprot.org/uniprot/Q2U9I8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL28 family. http://togogenome.org/gene/510516:AO090103000051 ^@ http://purl.uniprot.org/uniprot/Q2TYY9 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/510516:AO090005000693 ^@ http://purl.uniprot.org/uniprot/Q2URT8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090012000864 ^@ http://purl.uniprot.org/uniprot/Q2UBU2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat HIR1 family.|||Nucleus|||Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle. http://togogenome.org/gene/510516:AO090005000218 ^@ http://purl.uniprot.org/uniprot/Q2UT05 ^@ Similarity ^@ Belongs to the MNN1/MNT family. http://togogenome.org/gene/510516:AO090003000679 ^@ http://purl.uniprot.org/uniprot/Q2UKT8 ^@ Similarity ^@ In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.|||In the N-terminal section; belongs to the ubiquitin family. http://togogenome.org/gene/510516:AO090701000719 ^@ http://purl.uniprot.org/uniprot/Q2U7S6 ^@ Function|||Similarity ^@ Belongs to the SEC8 family.|||Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. http://togogenome.org/gene/510516:AO090001000449 ^@ http://purl.uniprot.org/uniprot/Q2UN98 ^@ Similarity ^@ Belongs to the neutral ceramidase family. http://togogenome.org/gene/510516:AO090003001054 ^@ http://purl.uniprot.org/uniprot/Q2UJV9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ING family.|||Component of an histone acetyltransferase complex.|||Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.|||Nucleus|||The PHD-type zinc finger mediates the binding to H3K4me3. http://togogenome.org/gene/510516:AO090009000443 ^@ http://purl.uniprot.org/uniprot/Q2UU61 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/510516:AO090701000408 ^@ http://purl.uniprot.org/uniprot/Q2U8J5 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/510516:AO090009000173 ^@ http://purl.uniprot.org/uniprot/Q2UUU5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 72 family.|||Cell membrane|||Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in cell wall morphogenesis. http://togogenome.org/gene/510516:AO090701000299 ^@ http://purl.uniprot.org/uniprot/Q2U8T6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.|||Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.|||Catalyzes the formation of S-adenosylmethionine from methionine and ATP. http://togogenome.org/gene/510516:AO090012000161 ^@ http://purl.uniprot.org/uniprot/Q2UDI4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090003000721 ^@ http://purl.uniprot.org/uniprot/Q2UKP9 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/510516:AO090103000382 ^@ http://purl.uniprot.org/uniprot/Q2TY58 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 4 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/510516:AO090010000261 ^@ http://purl.uniprot.org/uniprot/Q2TX70 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) per subunit.|||Homotetramer. http://togogenome.org/gene/510516:AO090003000828 ^@ http://purl.uniprot.org/uniprot/Q2UKF6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.|||Interacts with TAN1.|||RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.|||nucleolus http://togogenome.org/gene/510516:AO090026000375 ^@ http://purl.uniprot.org/uniprot/Q2UF27 ^@ Similarity ^@ Belongs to the tannase family. http://togogenome.org/gene/510516:AO090005001517 ^@ http://purl.uniprot.org/uniprot/Q2UPT5 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/510516:AO090023000319 ^@ http://purl.uniprot.org/uniprot/Q2UHT5 ^@ Similarity ^@ Belongs to the HscB family. http://togogenome.org/gene/510516:AO090701000167 ^@ http://purl.uniprot.org/uniprot/Q2U955 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NAC-alpha family.|||Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. Egd2 may also be involved in transcription regulation (By similarity).|||Cytoplasm|||Nucleus|||Part of the nascent polypeptide-associated complex (NAC), consisting of egd2 and egd1. NAC associates with ribosomes via egd1 (By similarity). http://togogenome.org/gene/510516:AO090103000130 ^@ http://purl.uniprot.org/uniprot/Q2TYS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090005001383 ^@ http://purl.uniprot.org/uniprot/Q2UQ57 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/510516:AO090005000682 ^@ http://purl.uniprot.org/uniprot/Q2URU9 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. http://togogenome.org/gene/510516:AO090020000603 ^@ http://purl.uniprot.org/uniprot/Q2U3V4 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FGGY kinase family.|||By D-xylose, L-arabinose or L-arabitol.|||Cytoplasm|||Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway (By similarity). http://togogenome.org/gene/510516:AO090005000751 ^@ http://purl.uniprot.org/uniprot/Q2URN7 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. http://togogenome.org/gene/510516:AO090012000136 ^@ http://purl.uniprot.org/uniprot/Q2UDK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090102000568 ^@ http://purl.uniprot.org/uniprot/Q2UA29 ^@ Similarity ^@ Belongs to the COG2 family. http://togogenome.org/gene/510516:AO090026000842 ^@ http://purl.uniprot.org/uniprot/Q2UDX6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090012000757 ^@ http://purl.uniprot.org/uniprot/Q2UC37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ThrE exporter (TC 2.A.79) family.|||Membrane http://togogenome.org/gene/510516:AO090102000011 ^@ http://purl.uniprot.org/uniprot/Q2UBD8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 28 family.|||Pectinolytic enzyme involved in the degradation of xylogalacturonan (xga), a galacturonan backbone heavily substituted with xylose, and which is one important component of the hairy regions of pectin. Activity requires a galacturonic acid backbone substituted with xylose (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090005001506 ^@ http://purl.uniprot.org/uniprot/Q2UPU4 ^@ Similarity ^@ Belongs to the isochorismatase family. http://togogenome.org/gene/510516:AO090012000451 ^@ http://purl.uniprot.org/uniprot/Q2UCT7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 1 family.|||Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090012001016 ^@ http://purl.uniprot.org/uniprot/Q2UBF9 ^@ Similarity ^@ Belongs to the SELO family. http://togogenome.org/gene/510516:AO090001000123 ^@ http://purl.uniprot.org/uniprot/Q2UP41 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/510516:AO090005000931 ^@ http://purl.uniprot.org/uniprot/Q2UR82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.|||Membrane http://togogenome.org/gene/510516:AO090023000611 ^@ http://purl.uniprot.org/uniprot/Q2UH28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the anthrone oxygenase family.|||Membrane http://togogenome.org/gene/510516:AO090001000033 ^@ http://purl.uniprot.org/uniprot/Q2UPB9 ^@ Function|||Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Probable aminotransferase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411). The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411). One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411). After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411). In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411). Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411). http://togogenome.org/gene/510516:AO090120000344 ^@ http://purl.uniprot.org/uniprot/Q2U681 ^@ Similarity ^@ Belongs to the protein disulfide isomerase family. http://togogenome.org/gene/510516:AO090701000190 ^@ http://purl.uniprot.org/uniprot/Q2U934 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090001000465 ^@ http://purl.uniprot.org/uniprot/Q2UN85 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.|||Belongs to the TDD superfamily. TSR3 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/510516:AO090103000452 ^@ http://purl.uniprot.org/uniprot/Q2TXZ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003001514 ^@ http://purl.uniprot.org/uniprot/Q2UIR2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pectinesterase family.|||Involved in maceration and soft-rotting of plant tissue.|||Secreted http://togogenome.org/gene/510516:AO090012000917 ^@ http://purl.uniprot.org/uniprot/Q2UBP7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/510516:AO090102000620 ^@ http://purl.uniprot.org/uniprot/Q2U9Y1 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/510516:AO090003000008 ^@ http://purl.uniprot.org/uniprot/Q2UMG7 ^@ Similarity|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Octamer of two non-identical subunits IDH1 and IDH2. http://togogenome.org/gene/510516:AO090026000037 ^@ http://purl.uniprot.org/uniprot/Q2UFX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090005000116 ^@ http://purl.uniprot.org/uniprot/Q2UT87 ^@ Similarity ^@ Belongs to the CDC6/cdc18 family. http://togogenome.org/gene/510516:AO090009000414 ^@ http://purl.uniprot.org/uniprot/Q2UU88 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/510516:AO090026000135 ^@ http://purl.uniprot.org/uniprot/Q2UFN6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/510516:AO090011000596 ^@ http://purl.uniprot.org/uniprot/Q2U044 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS11 family. http://togogenome.org/gene/510516:AO090103000172 ^@ http://purl.uniprot.org/uniprot/Q2TYN9 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/510516:AO090012000540 ^@ http://purl.uniprot.org/uniprot/Q2UCL4 ^@ Function|||Similarity ^@ Belongs to the tubulin family.|||Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. http://togogenome.org/gene/510516:AO090011000331 ^@ http://purl.uniprot.org/uniprot/Q2U0R8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090103000327 ^@ http://purl.uniprot.org/uniprot/Q2TYA6 ^@ Similarity ^@ Belongs to the TTC4 family. http://togogenome.org/gene/510516:AO090120000360 ^@ http://purl.uniprot.org/uniprot/Q2U667 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CTU2/NCS2 family.|||Cytoplasm|||Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with ncs6 that ligates sulfur from thiocarboxylated urm1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. http://togogenome.org/gene/510516:AO090020000631 ^@ http://purl.uniprot.org/uniprot/Q2U3T0 ^@ Similarity ^@ Belongs to the class-A beta-lactamase family. http://togogenome.org/gene/510516:AO090701000046 ^@ http://purl.uniprot.org/uniprot/Q2U9F8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.|||Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/510516:AO090102000457 ^@ http://purl.uniprot.org/uniprot/Q2UAB9 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/510516:AO090103000095 ^@ http://purl.uniprot.org/uniprot/Q2TYV4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090020000701 ^@ http://purl.uniprot.org/uniprot/Q2U3M1 ^@ Similarity ^@ Belongs to the flavin monoamine oxidase family. http://togogenome.org/gene/510516:AO090011000859 ^@ http://purl.uniprot.org/uniprot/Q2TZG7 ^@ Function ^@ Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint. http://togogenome.org/gene/510516:AO090009000626 ^@ http://purl.uniprot.org/uniprot/Q2UTR4 ^@ Similarity ^@ Belongs to the ATG101 family. http://togogenome.org/gene/510516:AO090009000239 ^@ http://purl.uniprot.org/uniprot/Q2UUN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the transient receptor potential (TRP) ion channel family.|||Membrane http://togogenome.org/gene/510516:AO090005000852 ^@ http://purl.uniprot.org/uniprot/Q2URF3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090001000377 ^@ http://purl.uniprot.org/uniprot/Q2UNG4 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/510516:AO090011000793 ^@ http://purl.uniprot.org/uniprot/Q2TZM7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Component of the MCM2-7 complex.|||Nucleus http://togogenome.org/gene/510516:AO090005001044 ^@ http://purl.uniprot.org/uniprot/P10281 ^@ Miscellaneous|||Similarity ^@ Belongs to the RNase T2 family.|||Preference for adenylic acid. http://togogenome.org/gene/510516:AO090010000708 ^@ http://purl.uniprot.org/uniprot/Q2TW47 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HIBADH-related family.|||Homodimer.|||NADPH-dependent reductive aminase that catalyzes the reductive coupling of a broad set of carbonyl compounds with a variety of primary and secondary amines (Ref.2). Possesses remarkably high activity for the reductive amination of ketones and amines, often with high stereoselectivity and in some cases with ketone:amine ratios as low as 1:1 (Ref.2). The cofactor NADPH, the carbonyl compound and the amine are added to the enzyme in that sequence, followed by the release of product, NADP(+) being released at last (Ref.2). RedAm is also able to act in the reverse, oxidative direction and exhibits activity in the dehydrogenation of amines to yield imines (Ref.2). The highest activity is found for 1-methyl-tetrahydroquinoline and acyclic amines are also found to be transformed (Ref.2). http://togogenome.org/gene/510516:AO090023000577 ^@ http://purl.uniprot.org/uniprot/Q2UH56 ^@ Function|||Similarity ^@ 2-hydroxyacid dehydrogenase that is capable to reduce pyruvate, hydroxypyruvate and glyoxylate in a NADPH- or NADH-dependent manner (PubMed:26615399). In contrast to 2-HadhD/morA, does not recognize 4-methyl-2-oxopentanoate (MOA) as a substrate (PubMed:26615399).|||Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/510516:AO090001000619 ^@ http://purl.uniprot.org/uniprot/Q2UMU6 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/510516:AO090120000479 ^@ http://purl.uniprot.org/uniprot/Q2U5W9 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/510516:AO090001000095 ^@ http://purl.uniprot.org/uniprot/Q2UP65 ^@ Similarity ^@ Belongs to the isochorismatase family. http://togogenome.org/gene/510516:AO090003000690 ^@ http://purl.uniprot.org/uniprot/Q2UKS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL49 family.|||Mitochondrion http://togogenome.org/gene/510516:AO090011000238 ^@ http://purl.uniprot.org/uniprot/Q2U0Z3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090009000567 ^@ http://purl.uniprot.org/uniprot/Q2UTW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.|||Membrane http://togogenome.org/gene/510516:AO090012000275 ^@ http://purl.uniprot.org/uniprot/Q2UD86 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.|||In the C-terminal section; belongs to the MoeA family.|||In the N-terminal section; belongs to the MoaB/Mog family. http://togogenome.org/gene/510516:AO090009000313 ^@ http://purl.uniprot.org/uniprot/Q2UUH4 ^@ Similarity ^@ Belongs to the calreticulin family. http://togogenome.org/gene/510516:AO090120000053 ^@ http://purl.uniprot.org/uniprot/Q2U6X7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090005000457 ^@ http://purl.uniprot.org/uniprot/Q2USE5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion.|||Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane.|||Mitochondrion matrix http://togogenome.org/gene/510516:AO090011000869 ^@ http://purl.uniprot.org/uniprot/Q2TZF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/510516:AO090012000445 ^@ http://purl.uniprot.org/uniprot/Q2UCU3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 35 family.|||Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.|||Secreted http://togogenome.org/gene/510516:AO090009000702 ^@ http://purl.uniprot.org/uniprot/Q2UTJ9 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/510516:AO090023000334 ^@ http://purl.uniprot.org/uniprot/Q2UHS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OS-9 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/510516:AO090001000749 ^@ http://purl.uniprot.org/uniprot/Q2UMH8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity).|||Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.|||nucleolus http://togogenome.org/gene/510516:AO090102000015 ^@ http://purl.uniprot.org/uniprot/Q2UBD4 ^@ Similarity ^@ Belongs to the DNA photolyase class-1 family. http://togogenome.org/gene/510516:AO090023000582 ^@ http://purl.uniprot.org/uniprot/Q2UH51 ^@ Function ^@ Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides. http://togogenome.org/gene/510516:AO090023000258 ^@ http://purl.uniprot.org/uniprot/Q2UHY6 ^@ Similarity ^@ Belongs to the DAMOX/DASOX family. http://togogenome.org/gene/510516:AO090001000546 ^@ http://purl.uniprot.org/uniprot/Q2UN10 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Cytoplasm|||Homotrimer.|||Nucleus http://togogenome.org/gene/510516:AO090003000948 ^@ http://purl.uniprot.org/uniprot/Q2UK53 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Membrane http://togogenome.org/gene/510516:AO090005000625 ^@ http://purl.uniprot.org/uniprot/Q2URZ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).|||Belongs to the NDUFAF7 family.|||Mitochondrion http://togogenome.org/gene/510516:AO090003001177 ^@ http://purl.uniprot.org/uniprot/Q2UJK3 ^@ Function|||Similarity ^@ Belongs to the UBR1 family.|||Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. http://togogenome.org/gene/510516:AO090038000040 ^@ http://purl.uniprot.org/uniprot/Q2U3H0 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/510516:AO090001000364 ^@ http://purl.uniprot.org/uniprot/Q2UNH6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL15 family. http://togogenome.org/gene/510516:AO090010000108 ^@ http://purl.uniprot.org/uniprot/Q2TXK4 ^@ Similarity|||Subunit ^@ Belongs to the fungal fatty acid synthetase subunit beta family.|||[Alpha(6)beta(6)] hexamers of two multifunctional subunits (alpha and beta). http://togogenome.org/gene/510516:AO090003000903 ^@ http://purl.uniprot.org/uniprot/Q2UK95 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.|||Cytoplasm|||Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. http://togogenome.org/gene/510516:AO090009000573 ^@ http://purl.uniprot.org/uniprot/Q2UTV6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090701000076 ^@ http://purl.uniprot.org/uniprot/Q2U9D2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the derlin family.|||Endoplasmic reticulum membrane|||May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.|||Membrane http://togogenome.org/gene/510516:AO090026000820 ^@ http://purl.uniprot.org/uniprot/Q2UDZ5 ^@ Similarity ^@ In the C-terminal section; belongs to the trehalose phosphatase family.|||In the N-terminal section; belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/510516:AO090026000677 ^@ http://purl.uniprot.org/uniprot/Q2UEC3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS5 family. http://togogenome.org/gene/510516:AO090206000058 ^@ http://purl.uniprot.org/uniprot/Q2PIU5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 40S cdc5-associated complex (or cwf complex), a spliceosome sub-complex reminiscent of a late-stage spliceosome.|||Belongs to the CWF11 family.|||Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.|||Nucleus http://togogenome.org/gene/510516:AO090102000570 ^@ http://purl.uniprot.org/uniprot/Q2UA27 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.|||Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of nbp35 and two labile, bridging clusters between subunits of the nbp35-cfd1 heterotetramer.|||Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The nbp35-cfd1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.|||Cytoplasm|||Heterotetramer of 2 nbp35 and 2 cfd1 chains. http://togogenome.org/gene/510516:AO090701000038 ^@ http://purl.uniprot.org/uniprot/Q2U9G6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/510516:AO090001000338 ^@ http://purl.uniprot.org/uniprot/Q2UNJ6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family. http://togogenome.org/gene/510516:AO090026000730 ^@ http://purl.uniprot.org/uniprot/Q2UE79 ^@ Similarity ^@ Belongs to the eukaryotic/archaeal RNase P protein component 1 family. http://togogenome.org/gene/510516:AO090005001084 ^@ http://purl.uniprot.org/uniprot/Q2UQV7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 31 family.|||Glucosidase involved in the degradation of cellulosic biomass. Has both alpha- and beta-glucosidase activity (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090102000265 ^@ http://purl.uniprot.org/uniprot/Q2UAS1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090124000015 ^@ http://purl.uniprot.org/uniprot/Q2U798 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/510516:AO090020000626 ^@ http://purl.uniprot.org/uniprot/Q2U3T4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Mitochondrion inner membrane|||Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. http://togogenome.org/gene/510516:AO090120000448 ^@ http://purl.uniprot.org/uniprot/Q2U5Z1 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090124000027 ^@ http://purl.uniprot.org/uniprot/Q2U786 ^@ Function|||Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.|||Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway. http://togogenome.org/gene/510516:AO090701000734 ^@ http://purl.uniprot.org/uniprot/Q2U7R4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATG3 family.|||Cytoplasm|||E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of atg8. The atg12-atg5 conjugate plays a role of an E3 and promotes the transfer of atg8 from atg3 to phosphatidylethanolamine (PE). This step is required for the membrane association of atg8. The formation of the atg8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt). The atg8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity).|||Monomer. Interacts with atg8 through an intermediate thioester bond through the C-terminal Gly of atg8. Also interacts with the 40 amino acid C-terminal region of the E1-like atg7 enzyme. Interacts also with the atg12-atg5 conjugate.|||The N-terminal region is involved in phosphatidylethanolamine-binding and is required for atg8-PE conjugation.|||The flexible region (FR) is required for atg7-binding.|||The handle region (HR) contains the atg8 interaction motif (AIM) and mediates binding to atg8. It is crucial for the cytoplasm-to-vacuole targeting pathway (By similarity). http://togogenome.org/gene/510516:AO090012000375 ^@ http://purl.uniprot.org/uniprot/Q2UD01 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/510516:AO090001000094 ^@ http://purl.uniprot.org/uniprot/Q2UP66 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for the ferulic acid decarboxylase FDC1. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Mitochondrion|||Oligomer. http://togogenome.org/gene/510516:AO090003001256 ^@ http://purl.uniprot.org/uniprot/Q2UJD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/510516:AO090003001309 ^@ http://purl.uniprot.org/uniprot/Q2UJ94 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/510516:AO090120000416 ^@ http://purl.uniprot.org/uniprot/Q2U618 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/510516:AO090026000012 ^@ http://purl.uniprot.org/uniprot/Q2UG03 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family. http://togogenome.org/gene/510516:AO090023000052 ^@ http://purl.uniprot.org/uniprot/Q2UIH6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/510516:AO090011000913 ^@ http://purl.uniprot.org/uniprot/Q2TZC3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/510516:AO090023000528 ^@ http://purl.uniprot.org/uniprot/Q2UH99 ^@ Similarity ^@ Belongs to the NRP synthetase family. http://togogenome.org/gene/510516:AO090003000718 ^@ http://purl.uniprot.org/uniprot/Q2UKQ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATG11 family.|||Homodimer.|||Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion.|||Membrane|||Preautophagosomal structure membrane|||Vacuole membrane http://togogenome.org/gene/510516:AO090003000148 ^@ http://purl.uniprot.org/uniprot/Q2UM43 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial Rho GTPase family.|||Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.|||Mitochondrion outer membrane http://togogenome.org/gene/510516:AO090005000405 ^@ http://purl.uniprot.org/uniprot/Q2USJ2 ^@ Cofactor|||Domain|||Function|||Subcellular Location Annotation|||Subunit ^@ Cu(2+) or Zn(2+).|||Mitochondrion inner membrane|||Monomer.|||Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Forms a redox cycle with ERV1 that involves a disulfide relay system. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS (By similarity).|||The CHCH domain contains a conserved twin Cys-X(9)-Cys motif which is required for import and stability of MIA40 in mitochondria. http://togogenome.org/gene/510516:AO090120000284 ^@ http://purl.uniprot.org/uniprot/Q2U6D5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat PROPPIN family.|||Component of the PI(3,5)P2 regulatory complex.|||Endosome membrane|||Preautophagosomal structure membrane|||The L/FRRG motif is essential for the cytoplasm to vacuole transport (Cvt) pathway, for the recruitment of atg8 and atg16 to the PAS in nutrient-rich medium, and for its recruitment to and dissociation from the PAS under starvation conditions.|||The N-terminus might form a beta-propeller domain involved in specific binding to phosphatidylinositol 3,5-bisphosphate (PIP2), leading to the association of the protein to the membrane.|||The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct atg9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity).|||Vacuole membrane http://togogenome.org/gene/510516:AO090020000558 ^@ http://purl.uniprot.org/uniprot/Q2U3Z3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090023000151 ^@ http://purl.uniprot.org/uniprot/Q2UI87 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 27 family.|||Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.|||Secreted http://togogenome.org/gene/510516:AO090011000778 ^@ http://purl.uniprot.org/uniprot/Q2TZP1 ^@ Similarity ^@ Belongs to the NEMF family. http://togogenome.org/gene/510516:AO090026000548 ^@ http://purl.uniprot.org/uniprot/Q2UEN7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.|||Belongs to the ALG10 glucosyltransferase family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/510516:AO090103000074 ^@ http://purl.uniprot.org/uniprot/P78581 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the tannase family.|||Heterooctamer of 4 33 kDa and 4 30 kDa subunits linked by disulfide bond(s).|||Hydrolyzes ester bonds of tannic acid to produce gallic acid and glucose.|||The N-terminus of the 30 kDa subunit is blocked.|||The protein is glycosylated to a carbohydrate content of 22.7%. http://togogenome.org/gene/510516:AO090120000238 ^@ http://purl.uniprot.org/uniprot/Q2U6H2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).|||Cytoplasm http://togogenome.org/gene/510516:AO090003001353 ^@ http://purl.uniprot.org/uniprot/Q2UJ53 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090102000313 ^@ http://purl.uniprot.org/uniprot/Q2UAN6 ^@ Similarity ^@ Belongs to the MSOX/MTOX family. http://togogenome.org/gene/510516:AO090011000693 ^@ http://purl.uniprot.org/uniprot/Q2TZW5 ^@ Similarity ^@ Belongs to the PhyH family. http://togogenome.org/gene/510516:AO090023000263 ^@ http://purl.uniprot.org/uniprot/Q2UHY2 ^@ Cofactor|||Subcellular Location Annotation ^@ Binds 1 Ca(2+) ion per subunit.|||extracellular space http://togogenome.org/gene/510516:AO090701000710 ^@ http://purl.uniprot.org/uniprot/Q2U7T3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090102000101 ^@ http://purl.uniprot.org/uniprot/Q2UB56 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sorting nexin family.|||Cytoplasm|||Membrane|||Required for vacuolar protein sorting.|||The PX domain binds phosphatidylinositol 3-phosphate which is necessary for peripheral membrane localization. http://togogenome.org/gene/510516:AO090038000386 ^@ http://purl.uniprot.org/uniprot/Q2U2N4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family. RAD51 subfamily.|||Nucleus|||Required both for recombination and for the repair of DNA damage caused by X-rays. http://togogenome.org/gene/510516:AO090023000245 ^@ http://purl.uniprot.org/uniprot/Q2UHZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090023000192 ^@ http://purl.uniprot.org/uniprot/Q2UI50 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090009000275 ^@ http://purl.uniprot.org/uniprot/Q2UUL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090001000127 ^@ http://purl.uniprot.org/uniprot/Q2UP37 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/510516:AO090005000146 ^@ http://purl.uniprot.org/uniprot/Q2UT59 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/510516:AO090701000094 ^@ http://purl.uniprot.org/uniprot/Q2U9B8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the calcineurin regulatory subunit family.|||Composed of a catalytic subunit (A) and a regulatory subunit (B).|||Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. http://togogenome.org/gene/510516:AO090011000588 ^@ http://purl.uniprot.org/uniprot/Q2U050 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uricase family.|||Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.|||Peroxisome http://togogenome.org/gene/510516:AO090003001364 ^@ http://purl.uniprot.org/uniprot/Q2UJ43 ^@ Similarity ^@ Belongs to the D-glutamate cyclase family. http://togogenome.org/gene/510516:AO090701000209 ^@ http://purl.uniprot.org/uniprot/Q2U918 ^@ Domain|||Function|||Similarity ^@ Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.|||Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism.|||Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine. http://togogenome.org/gene/510516:AO090206000054 ^@ http://purl.uniprot.org/uniprot/Q2PIU8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the timeless family.|||Involved in chromosome segregation during meiosis and DNA damage repair.|||Nucleus http://togogenome.org/gene/510516:AO090005000265 ^@ http://purl.uniprot.org/uniprot/Q2USW5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS15 family. http://togogenome.org/gene/510516:AO090003000268 ^@ http://purl.uniprot.org/uniprot/Q2ULU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/510516:AO090138000018 ^@ http://purl.uniprot.org/uniprot/Q2U210 ^@ Function|||Subcellular Location Annotation ^@ Cell wall formation.|||Cytoplasm http://togogenome.org/gene/510516:AO090120000461 ^@ http://purl.uniprot.org/uniprot/Q2U5Y1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Endoplasmic reticulum membrane|||Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. http://togogenome.org/gene/510516:AO090009000575 ^@ http://purl.uniprot.org/uniprot/Q2UTV5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family.|||Binds 1 or 2 Zn(2+) ions per subunit.|||Xylitol dehydrogenase which catalyzes the conversion of xylitol to D-xylulose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway. http://togogenome.org/gene/510516:AO090003000096 ^@ http://purl.uniprot.org/uniprot/Q2UM88 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/510516:AO090103000169 ^@ http://purl.uniprot.org/uniprot/Q2TYP1 ^@ Similarity ^@ Belongs to the lysine N-acyltransferase MbtK family. http://togogenome.org/gene/510516:AO090113000085 ^@ http://purl.uniprot.org/uniprot/Q2U5M4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UTP23/FCF1 family. FCF1 subfamily.|||nucleolus http://togogenome.org/gene/510516:AO090009000651 ^@ http://purl.uniprot.org/uniprot/Q2UTP2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090023000426 ^@ http://purl.uniprot.org/uniprot/Q2UHJ2 ^@ Similarity ^@ Belongs to the TYW1 family. http://togogenome.org/gene/510516:AO090001000151 ^@ http://purl.uniprot.org/uniprot/Q2UP15 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. http://togogenome.org/gene/510516:AO090003000611 ^@ http://purl.uniprot.org/uniprot/Q2UKZ2 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. HMG-CoA synthase family.|||Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA. http://togogenome.org/gene/510516:AO090113000186 ^@ http://purl.uniprot.org/uniprot/Q2U5D7 ^@ Similarity ^@ Belongs to the flavin monoamine oxidase family. http://togogenome.org/gene/510516:AO090005001175 ^@ http://purl.uniprot.org/uniprot/Q2UQN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat peroxin-7 family.|||Cytoplasm http://togogenome.org/gene/510516:AO090011000118 ^@ http://purl.uniprot.org/uniprot/P00651 ^@ Similarity|||Subunit ^@ Belongs to the ribonuclease N1/T1 family.|||Monomer. http://togogenome.org/gene/510516:AO090003001197 ^@ http://purl.uniprot.org/uniprot/Q2UJI6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP core protein family.|||Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.|||Component of the heptameric LSM1-LSM7 complex, which consists of LSM1, LSM2, LSM3, LSM4, LSM5, LSM6 and LSM7. Component of the heptameric LSM2-LSM8 complex, which consists of LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8. The LSm subunits form a seven-membered ring structure with a doughnut shape.|||Nucleus|||cytosol http://togogenome.org/gene/510516:AO090701000886 ^@ http://purl.uniprot.org/uniprot/Q2U7D1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/510516:AO090010000767 ^@ http://purl.uniprot.org/uniprot/Q2TVY9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CGR1 family.|||Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.|||nucleolus http://togogenome.org/gene/510516:AO090103000443 ^@ http://purl.uniprot.org/uniprot/Q2TY02 ^@ Similarity ^@ Belongs to the oxoprolinase family. http://togogenome.org/gene/510516:AO090012000979 ^@ http://purl.uniprot.org/uniprot/Q2UBI9 ^@ Subcellular Location Annotation ^@ Membrane|||Vacuole membrane http://togogenome.org/gene/510516:AO090005000615 ^@ http://purl.uniprot.org/uniprot/Q2US08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS2 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/510516:AO090001000031 ^@ http://purl.uniprot.org/uniprot/Q2UPC1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily.|||MFS efflux transporter; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411).|||Membrane http://togogenome.org/gene/510516:AO090011000599 ^@ http://purl.uniprot.org/uniprot/Q2U041 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit L family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/510516:AO090701000402 ^@ http://purl.uniprot.org/uniprot/Q2U8K1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000438 ^@ http://purl.uniprot.org/uniprot/Q2USG3 ^@ Similarity|||Subunit ^@ Belongs to the LDH/MDH superfamily. MDH type 1 family.|||Homodimer. http://togogenome.org/gene/510516:AO090003001064 ^@ http://purl.uniprot.org/uniprot/Q2UJU9 ^@ Function|||Similarity ^@ Belongs to the VPS13 family.|||Mediates the transfer of lipids between membranes at organelle contact sites. May play a role in mitochondrial lipid homeostasis. http://togogenome.org/gene/510516:AO090023000729 ^@ http://purl.uniprot.org/uniprot/Q2UGS5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.|||Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate-binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions.|||Heterodimer consisting of MSH2-MSH3 (MutS beta). Forms a ternary complex with MutL alpha (MLH1-PMS1).|||Nucleus http://togogenome.org/gene/510516:AO090003000124 ^@ http://purl.uniprot.org/uniprot/Q2UM63 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. http://togogenome.org/gene/510516:AO090103000331 ^@ http://purl.uniprot.org/uniprot/Q2TYA2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS13 family. http://togogenome.org/gene/510516:AO090012001025 ^@ http://purl.uniprot.org/uniprot/Q2UBF0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M43B family.|||Secreted|||Secreted metalloproteinase that allows assimilation of proteinaceous substrates. http://togogenome.org/gene/510516:AO090003000040 ^@ http://purl.uniprot.org/uniprot/Q2UMD7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090023000837 ^@ http://purl.uniprot.org/uniprot/Q2UGH7 ^@ Function|||Similarity ^@ Belongs to the vitamin-B12 independent methionine synthase family.|||Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation. http://togogenome.org/gene/510516:AO090003000453 ^@ http://purl.uniprot.org/uniprot/Q2ULD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNF2/RAD54 helicase family.|||Nucleus http://togogenome.org/gene/510516:AO090026000579 ^@ http://purl.uniprot.org/uniprot/Q2UEK7 ^@ Disruption Phenotype|||Function|||Induction|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of astellolides, drimane-type sesquiterpene esters that show antimicrobial, anti-inflammatory, and anti-tumor activities (PubMed:27628599). The first step in astellolide biosynthesis is performed by the sesquiterpene cyclase astC that catalyzes the formation of drimanyl pyrophosphate from farnesyl pyrophosphate (PubMed:27628599). Drimanyl pyrophosphate is then dephosphorylated by the sesquiterpene phosphatase astI to produce drimanyl monophosphate which is further dephosphorylated to drim-8-ene-11-ol by atsK (PubMed:27628599). Drim-8-ene-11-ol is converted to confertifolin, probably by the cytochrome P450 monooxygenase astD and/or the dehydrogenase astE (PubMed:27628599). The cytochrome P450 monooxygenases astB, astF and astJ then hydroxylate confertifolin at C6, C14, or C15 to form trihydroxy confertifolin (PubMed:27628599). The nonribosomal peptide synthetase astA catalyzes ester bond formation between trihydroxy contifolin and benzoic acid (BA) or 4-hydroxy benzoic acid (4HBA), leading to the formation of dideacetyl astellolides A and B, respectively (PubMed:27628599). Finally, the O-acetyltransferase astG converts dideacetyl astellolides A and B into deacetyl astellolides A and B (PubMed:27628599).|||Expression is regulated by the secondary metabolite regulator cclA.|||Impairs the production of trihydroxy confertifolin and deacetyl astellolides A and B.|||Membrane http://togogenome.org/gene/510516:AO090020000117 ^@ http://purl.uniprot.org/uniprot/Q2U515 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090023000363 ^@ http://purl.uniprot.org/uniprot/Q2UHP5 ^@ Similarity ^@ Belongs to the PhyH family. http://togogenome.org/gene/510516:AO090026000083 ^@ http://purl.uniprot.org/uniprot/Q8NK92 ^@ Activity Regulation|||Cofactor|||Developmental Stage|||Function|||PTM|||Subcellular Location Annotation ^@ Activity found in solid culture only. Increases at the initial growth stage and decreases in the late growth stage.|||Binds 1 Ca(2+) ion per subunit.|||Inhibited by antipain and leupeptin.|||N-glycosylated.|||O-glycosylated.|||Serine endopeptidase which hydrolyzes a range of fluorogenic peptide substrates containing the basic residues arginine or lysine at the P1 position and prefers paired basic resides. Also hydrolyzes clupeine and salmine, activates plasminogen and converts trypsinogen to trypsin.|||extracellular space http://togogenome.org/gene/510516:AO090003001231 ^@ http://purl.uniprot.org/uniprot/Q2UJG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDC37 family.|||Cytoplasm http://togogenome.org/gene/510516:AO090003000147 ^@ http://purl.uniprot.org/uniprot/Q2UM44 ^@ Similarity ^@ Belongs to the SH3YL1 family. http://togogenome.org/gene/510516:AO090026000063 ^@ http://purl.uniprot.org/uniprot/Q2UFV5 ^@ Similarity ^@ Belongs to the chloroperoxidase family. http://togogenome.org/gene/510516:AO090103000087 ^@ http://purl.uniprot.org/uniprot/Q2TYW2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 61 family.|||Has a modular structure: an endo-beta-1,4-glucanase catalytic module at the N-terminus, a linker rich in serines and threonines, and a C-terminal carbohydrate-binding module (CBM). The genes for catalytic modules and CBMs seem to have evolved separately and have been linked by gene fusion.|||Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan. Involved in the degradation of complex natural cellulosic substrates.|||Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds. Involved in the degradation of complex natural cellulosic substrates.|||Secreted http://togogenome.org/gene/510516:AO090120000132 ^@ http://purl.uniprot.org/uniprot/Q2U6Q9 ^@ Similarity ^@ Belongs to the acetyltransferase family. GNA1 subfamily. http://togogenome.org/gene/510516:AO090701000130 ^@ http://purl.uniprot.org/uniprot/Q2U987 ^@ Similarity ^@ Belongs to the COG1 family. http://togogenome.org/gene/510516:AO090010000429 ^@ http://purl.uniprot.org/uniprot/Q2TWT5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090102000115 ^@ http://purl.uniprot.org/uniprot/Q2UB44 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CBF/MAK21 family.|||Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm.|||nucleolus http://togogenome.org/gene/510516:AO090003000210 ^@ http://purl.uniprot.org/uniprot/Q2ULZ3 ^@ Similarity ^@ Belongs to the homogentisate dioxygenase family. http://togogenome.org/gene/510516:AO090001000549 ^@ http://purl.uniprot.org/uniprot/Q2UN07 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/510516:AO090020000297 ^@ http://purl.uniprot.org/uniprot/Q2U4L0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS4 family. http://togogenome.org/gene/510516:AO090102000122 ^@ http://purl.uniprot.org/uniprot/Q2UB39 ^@ Similarity ^@ Belongs to the CAF1 family. http://togogenome.org/gene/510516:AO090003000586 ^@ http://purl.uniprot.org/uniprot/Q2UL15 ^@ Function|||Similarity ^@ Belongs to the VPS35 family.|||Plays a role in vesicular protein sorting. http://togogenome.org/gene/510516:AO090012000410 ^@ http://purl.uniprot.org/uniprot/Q2UCX4 ^@ Similarity ^@ Belongs to the REXO1/REXO3 family. http://togogenome.org/gene/510516:AO090001000339 ^@ http://purl.uniprot.org/uniprot/Q2UNJ5 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/510516:AO090026000636 ^@ http://purl.uniprot.org/uniprot/Q2UEF7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EFG1 family.|||Involved in rRNA processing.|||nucleolus http://togogenome.org/gene/510516:AO090012000220 ^@ http://purl.uniprot.org/uniprot/Q2UDD1 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/510516:AO090701000481 ^@ http://purl.uniprot.org/uniprot/Q2U8C6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 43 family.|||Endo-1,5-alpha-L-arabinanase involved in degradation of pectin. Its preferred substrate is linear 1,5-alpha-L-arabinan (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090005001358 ^@ http://purl.uniprot.org/uniprot/Q2UQ80 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/510516:AO090003000002 ^@ http://purl.uniprot.org/uniprot/Q2UMH3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class V-like SAM-binding methyltransferase superfamily.|||Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.|||Chromosome|||Component of the COMPASS (Set1C) complex.|||Nucleus http://togogenome.org/gene/510516:AO090003000055 ^@ http://purl.uniprot.org/uniprot/Q12560 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the enolase family.|||Cytoplasm|||Homodimer.|||Mg(2+) is required for catalysis and for stabilizing the dimer. http://togogenome.org/gene/510516:AO090003001525 ^@ http://purl.uniprot.org/uniprot/Q2UIQ3 ^@ Similarity ^@ Belongs to the amidase family. http://togogenome.org/gene/510516:AO090003001115 ^@ http://purl.uniprot.org/uniprot/Q2UJQ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I 51 kDa subunit family.|||Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090103000159 ^@ http://purl.uniprot.org/uniprot/Q2TYP9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090011000374 ^@ http://purl.uniprot.org/uniprot/Q2U0M8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090012000427 ^@ http://purl.uniprot.org/uniprot/Q2UCW0 ^@ Similarity ^@ Belongs to the proteasome subunit S5A family. http://togogenome.org/gene/510516:AO090009000436 ^@ http://purl.uniprot.org/uniprot/Q2UU67 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.|||Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090003001252 ^@ http://purl.uniprot.org/uniprot/Q2UJE3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090026000314 ^@ http://purl.uniprot.org/uniprot/Q2UF79 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PI3/PI4-kinase family.|||Cell membrane|||Vacuole membrane http://togogenome.org/gene/510516:AO090011000508 ^@ http://purl.uniprot.org/uniprot/Q2U0B4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DASH complex SPC19 family.|||Nucleus|||kinetochore http://togogenome.org/gene/510516:AO090009000477 ^@ http://purl.uniprot.org/uniprot/Q2UU34 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LIMR family. LMBRD1 subfamily.|||Lysosome membrane|||Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors. http://togogenome.org/gene/510516:AO090026000549 ^@ http://purl.uniprot.org/uniprot/Q2UEN6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GINS2/PSF2 family.|||Component of the GINS complex which is a heterotetramer of sld5, psf1, psf2 and psf3.|||Nucleus|||The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation (By similarity). http://togogenome.org/gene/510516:AO090010000126 ^@ http://purl.uniprot.org/uniprot/Q2TXI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090011000851 ^@ http://purl.uniprot.org/uniprot/Q2TZH4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.|||Chromosome|||Histone methyltransferase that trimethylates 'Lys-20' of histone H4 to form H4K20me3.|||Nucleus http://togogenome.org/gene/510516:AO090026000265 ^@ http://purl.uniprot.org/uniprot/Q2UFB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Mitochondrion matrix http://togogenome.org/gene/510516:AO090005000108 ^@ http://purl.uniprot.org/uniprot/Q2UT93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BIG1 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/510516:AO090003000547 ^@ http://purl.uniprot.org/uniprot/Q2UL51 ^@ Similarity ^@ Belongs to the MSOX/MTOX family. http://togogenome.org/gene/510516:AO090102000560 ^@ http://purl.uniprot.org/uniprot/Q2UA36 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003001377 ^@ http://purl.uniprot.org/uniprot/Q2UJ30 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090001000710 ^@ http://purl.uniprot.org/uniprot/Q2UML5 ^@ Similarity ^@ Belongs to the hexokinase family. http://togogenome.org/gene/510516:AO090012000680 ^@ http://purl.uniprot.org/uniprot/Q2UCA1 ^@ Function|||Similarity ^@ Belongs to the lysophospholipase family.|||Catalyzes the release of fatty acids from lysophospholipids. http://togogenome.org/gene/510516:AO090026000701 ^@ http://purl.uniprot.org/uniprot/Q2UEA3 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/510516:AO090023000988 ^@ http://purl.uniprot.org/uniprot/Q2UG41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090010000198 ^@ http://purl.uniprot.org/uniprot/Q2TXC7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090120000102 ^@ http://purl.uniprot.org/uniprot/Q2U6T7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090023000863 ^@ http://purl.uniprot.org/uniprot/Q2UGF3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c-type heme lyase family.|||Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090124000018 ^@ http://purl.uniprot.org/uniprot/Q2U795 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/510516:AO090124000019 ^@ http://purl.uniprot.org/uniprot/Q2U794 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/510516:AO090003000180 ^@ http://purl.uniprot.org/uniprot/Q2UM16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COX15/CtaA family.|||Membrane http://togogenome.org/gene/510516:AO090003000873 ^@ http://purl.uniprot.org/uniprot/Q2UKB8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.|||May mediate the reduction of outer membrane cytochrome b5.|||Mitochondrion outer membrane http://togogenome.org/gene/510516:AO090011000775 ^@ http://purl.uniprot.org/uniprot/Q2TZP4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL30 family. http://togogenome.org/gene/510516:AO090009000588 ^@ http://purl.uniprot.org/uniprot/Q2UTU6 ^@ Similarity ^@ Belongs to the MSOX/MTOX family. http://togogenome.org/gene/510516:AO090005001380 ^@ http://purl.uniprot.org/uniprot/Q2UQ60 ^@ Cofactor|||Subcellular Location Annotation ^@ Binds 1 Ca(2+) ion per subunit.|||extracellular space http://togogenome.org/gene/510516:AO090023000038 ^@ http://purl.uniprot.org/uniprot/Q2UII9 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family. http://togogenome.org/gene/510516:AO090026000747 ^@ http://purl.uniprot.org/uniprot/Q2UE64 ^@ Similarity ^@ Belongs to the NmrA-type oxidoreductase family. http://togogenome.org/gene/510516:AO090011000832 ^@ http://purl.uniprot.org/uniprot/Q2TZJ2 ^@ Similarity ^@ Belongs to the NSRP1 family. http://togogenome.org/gene/510516:AO090103000459 ^@ http://purl.uniprot.org/uniprot/Q2TXY8 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/510516:AO090023000271 ^@ http://purl.uniprot.org/uniprot/Q2UHX5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090120000352 ^@ http://purl.uniprot.org/uniprot/Q2U674 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. http://togogenome.org/gene/510516:AO090023000242 ^@ http://purl.uniprot.org/uniprot/Q2UI01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sphingosine N-acyltransferase family.|||Membrane http://togogenome.org/gene/510516:AO090113000136 ^@ http://purl.uniprot.org/uniprot/Q2U5I0 ^@ Biotechnology|||Disruption Phenotype|||Function|||Induction|||Similarity ^@ Belongs to the aromatic-ring hydroxylase family.|||Expression is controlled by the kojic acid gene cluster transcription factor kojR (PubMed:21514215). Expression is also positively regulated by the secondary metabolism general regulator laeA (PubMed:21897021). Expression is negatively regulated by the transcription factor kpeA (PubMed:30790620). Finally, nitrogen deficiency increases the expression (PubMed:26657710).|||Kojic acid can be used for several biotechnological applications, including use as an antibiotic, as an additive to prevent browning of food materials, and as an antioxidant (PubMed:17119644). Kojic acid is also interesting as an inhibitor of tyrosinase (PubMed:7714722). Finally, kojic acid has also been shown to have strong nematicidal activity (PubMed:27197670).|||Leads to the loss of kojic acid production.|||Probable FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of 5-hydroxy-2-hydroxymethyl-1,4-pyrone, also know as kojic acid, a by-product in the fermentation process of malting rice that acts as a chelation agent (PubMed:20849972, PubMed:35034313). Glucose might be converted to kojic acid by a combination of dehydrogenase and dehydratase reactions involving kojA and probably additional enzymes (PubMed:20849972). http://togogenome.org/gene/510516:AO090005001646 ^@ http://purl.uniprot.org/uniprot/Q2UPH0 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/510516:AO090005000754 ^@ http://purl.uniprot.org/uniprot/Q2URN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VTA1 family.|||Cytoplasm|||Endosome membrane|||Membrane http://togogenome.org/gene/510516:AO090003001474 ^@ http://purl.uniprot.org/uniprot/Q2UIU5 ^@ Similarity ^@ Belongs to the isochorismatase family. http://togogenome.org/gene/510516:AO090138000061 ^@ http://purl.uniprot.org/uniprot/Q2U1X2 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/510516:AO090005000720 ^@ http://purl.uniprot.org/uniprot/Q2URR3 ^@ Similarity ^@ Belongs to the Mo25 family. http://togogenome.org/gene/510516:AO090011000572 ^@ http://purl.uniprot.org/uniprot/Q2U062 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/510516:AO090005000528 ^@ http://purl.uniprot.org/uniprot/Q2US86 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/510516:AO090038000567 ^@ http://purl.uniprot.org/uniprot/Q2U280 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090011000782 ^@ http://purl.uniprot.org/uniprot/Q2TZN8 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/510516:AO090103000333 ^@ http://purl.uniprot.org/uniprot/Q2TYA0 ^@ Similarity ^@ Belongs to the SDO1/SBDS family. http://togogenome.org/gene/510516:AO090102000026 ^@ http://purl.uniprot.org/uniprot/Q2UBC5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090166000099 ^@ http://purl.uniprot.org/uniprot/Q2U9L8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090001000136 ^@ http://purl.uniprot.org/uniprot/Q2UP29 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. http://togogenome.org/gene/510516:AO090701000024 ^@ http://purl.uniprot.org/uniprot/Q2U9H9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily. http://togogenome.org/gene/510516:AO090102000594 ^@ http://purl.uniprot.org/uniprot/Q2UA04 ^@ Similarity ^@ Belongs to the RRP15 family. http://togogenome.org/gene/510516:AO090023000653 ^@ http://purl.uniprot.org/uniprot/Q2UGZ2 ^@ Function|||Similarity ^@ Belongs to the DPH4 family.|||Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. http://togogenome.org/gene/510516:AO090701000018 ^@ http://purl.uniprot.org/uniprot/Q2U9I4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090206000038 ^@ http://purl.uniprot.org/uniprot/Q2PIW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.|||Membrane http://togogenome.org/gene/510516:AO090001000395 ^@ http://purl.uniprot.org/uniprot/Q2UNE8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090010000309 ^@ http://purl.uniprot.org/uniprot/Q2TX31 ^@ Similarity ^@ Belongs to the NmrA-type oxidoreductase family. http://togogenome.org/gene/510516:AO090005001077 ^@ http://purl.uniprot.org/uniprot/Q2UQW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase g subunit family.|||Membrane http://togogenome.org/gene/510516:AO090001000051 ^@ http://purl.uniprot.org/uniprot/Q2UPA1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090026000120 ^@ http://purl.uniprot.org/uniprot/Q2UFQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 28 family.|||Secreted http://togogenome.org/gene/510516:AO090038000357 ^@ http://purl.uniprot.org/uniprot/Q2U2Q7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.|||Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.|||Catalyzes the formation of S-adenosylmethionine from methionine and ATP. http://togogenome.org/gene/510516:AO090023000297 ^@ http://purl.uniprot.org/uniprot/Q2UHV4 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/510516:AO090701000451 ^@ http://purl.uniprot.org/uniprot/Q2U8F4 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. http://togogenome.org/gene/510516:AO090003001024 ^@ http://purl.uniprot.org/uniprot/Q2UJY4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TIM54 family.|||Component of the TIM22 complex, whose core is composed of TIM22 and TIM54, associated with the 70 kDa heterohexamer composed of TIM9 and TIM10 (or TIM8 and TIM13).|||Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090010000119 ^@ http://purl.uniprot.org/uniprot/Q2TXJ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005001455 ^@ http://purl.uniprot.org/uniprot/Q2UPY9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090001000525 ^@ http://purl.uniprot.org/uniprot/Q2UN31 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion.|||Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity).|||Mitochondrion matrix http://togogenome.org/gene/510516:AO090010000519 ^@ http://purl.uniprot.org/uniprot/Q2TWK7 ^@ Similarity ^@ Belongs to the gamma-glutamylcyclotransferase family. http://togogenome.org/gene/510516:AO090701000720 ^@ http://purl.uniprot.org/uniprot/Q2U7S5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M24B family.|||Binds 2 manganese ions per subunit.|||Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides. http://togogenome.org/gene/510516:AO090011000789 ^@ http://purl.uniprot.org/uniprot/Q2TZN1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090005000316 ^@ http://purl.uniprot.org/uniprot/Q2USS0 ^@ Similarity ^@ Belongs to the amidase family. http://togogenome.org/gene/510516:AO090102000499 ^@ http://purl.uniprot.org/uniprot/Q2UA86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IMPACT family.|||Cytoplasm http://togogenome.org/gene/510516:AO090011000577 ^@ http://purl.uniprot.org/uniprot/Q2U058 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat COPB2 family.|||COPI-coated vesicle membrane|||Golgi apparatus membrane|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/510516:AO090010000005 ^@ http://purl.uniprot.org/uniprot/Q2TXU8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090102000388 ^@ http://purl.uniprot.org/uniprot/Q2UAH1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005001372 ^@ http://purl.uniprot.org/uniprot/Q2UQ67 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/510516:AO090003001112 ^@ http://purl.uniprot.org/uniprot/Q2UJR1 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/510516:AO090003000842 ^@ http://purl.uniprot.org/uniprot/Q877B9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small GTPase superfamily. SAR1 family.|||COPII is composed of at least 5 proteins: the sec23/24 complex, the sec13/31 complex and sar1.|||COPII-coated vesicle membrane|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. Sar1 controls the coat assembly in a stepwise manner. Activated Sar1-GTP binds to membranes first and recruits the sec23/24 complex. These sec23/24-sar1 prebudding intermediates are then collected by the Sec13/31 complex as subunits polymerize to form coated transport vesicles. Conversion to sar1-GDP triggers coat release and recycles COPII subunits (By similarity). http://togogenome.org/gene/510516:AO090020000497 ^@ http://purl.uniprot.org/uniprot/Q2U446 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090038000498 ^@ http://purl.uniprot.org/uniprot/Q2U2D3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090113000088 ^@ http://purl.uniprot.org/uniprot/Q2U5M1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090005001090 ^@ http://purl.uniprot.org/uniprot/Q2UQV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 16 family.|||Cell membrane|||Membrane http://togogenome.org/gene/510516:AO090005001642 ^@ http://purl.uniprot.org/uniprot/Q2UPH3 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. http://togogenome.org/gene/510516:AO090012000745 ^@ http://purl.uniprot.org/uniprot/Q2UC46 ^@ Function ^@ Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. http://togogenome.org/gene/510516:AO090001000693 ^@ http://purl.uniprot.org/uniprot/Q2UMN2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.|||Cell membrane|||Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. http://togogenome.org/gene/510516:AO090010000773 ^@ http://purl.uniprot.org/uniprot/Q2TVY3 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. http://togogenome.org/gene/510516:AO090001000737 ^@ http://purl.uniprot.org/uniprot/Q2UMI9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090038000092 ^@ http://purl.uniprot.org/uniprot/Q2U3C8 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/510516:AO090113000147 ^@ http://purl.uniprot.org/uniprot/Q2U5G9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090009000469 ^@ http://purl.uniprot.org/uniprot/Q2UU42 ^@ Similarity ^@ Belongs to the FMO family. http://togogenome.org/gene/510516:AO090701000858 ^@ http://purl.uniprot.org/uniprot/Q2U7F7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090020000607 ^@ http://purl.uniprot.org/uniprot/Q2U3V1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090010000014 ^@ http://purl.uniprot.org/uniprot/Q2TXT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acyl-CoA oxidase family.|||Peroxisome http://togogenome.org/gene/510516:AO090038000597 ^@ http://purl.uniprot.org/uniprot/Q2U253 ^@ Similarity ^@ Belongs to the RRP7 family. http://togogenome.org/gene/510516:AO090010000603 ^@ http://purl.uniprot.org/uniprot/Q2TWD5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the chloride channel (TC 2.A.49) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/510516:AO090003000081 ^@ http://purl.uniprot.org/uniprot/Q2UMA1 ^@ Cofactor|||Similarity ^@ Belongs to the chorismate synthase family.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/510516:AO090020000536 ^@ http://purl.uniprot.org/uniprot/Q2U412 ^@ Similarity ^@ Belongs to the amino acid/polyamine transporter 2 family. http://togogenome.org/gene/510516:AO090023000191 ^@ http://purl.uniprot.org/uniprot/Q2UI51 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000326 ^@ http://purl.uniprot.org/uniprot/Q2USR2 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/510516:AO090009000362 ^@ http://purl.uniprot.org/uniprot/Q2UUD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERG4/ERG24 family.|||Membrane http://togogenome.org/gene/510516:AO090003000057 ^@ http://purl.uniprot.org/uniprot/Q2UMC2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycosyl hydrolase 47 family.|||Cytoplasmic vesicle lumen|||Involved in the maturation of Asn-linked oligosaccharides. Progressively trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).|||Monomer. http://togogenome.org/gene/510516:AO090012000660 ^@ http://purl.uniprot.org/uniprot/Q2UCB7 ^@ Function|||Similarity ^@ Belongs to the peptidase C14B family.|||Involved in cell death (apoptosis). http://togogenome.org/gene/510516:AO090003000884 ^@ http://purl.uniprot.org/uniprot/Q2UKB1 ^@ Similarity ^@ Belongs to the NPR2 family. http://togogenome.org/gene/510516:AO090701000124 ^@ http://purl.uniprot.org/uniprot/Q2U992 ^@ Similarity ^@ Belongs to the XPO2/CSE1 family. http://togogenome.org/gene/510516:AO090206000022 ^@ http://purl.uniprot.org/uniprot/Q2PIX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family.|||Cytoplasm http://togogenome.org/gene/510516:AO090701000389 ^@ http://purl.uniprot.org/uniprot/Q2U8L0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 72 family.|||Cell membrane|||Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in cell wall morphogenesis. http://togogenome.org/gene/510516:AO090138000028 ^@ http://purl.uniprot.org/uniprot/Q2U203 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/510516:AO090005000759 ^@ http://purl.uniprot.org/uniprot/Q2URN0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the eukaryotic-type primase large subunit family.|||Binds 1 [4Fe-4S] cluster.|||DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. http://togogenome.org/gene/510516:AO090026000791 ^@ http://purl.uniprot.org/uniprot/Q2UE21 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/510516:AO090120000212 ^@ http://purl.uniprot.org/uniprot/Q2U6J3 ^@ Similarity ^@ Belongs to the RNase PH family. http://togogenome.org/gene/510516:AO090012000006 ^@ http://purl.uniprot.org/uniprot/Q2UDW2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/510516:AO090005000987 ^@ http://purl.uniprot.org/uniprot/Q2UR37 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090010000018 ^@ http://purl.uniprot.org/uniprot/Q2TXT6 ^@ Similarity ^@ Belongs to the aegerolysin family. http://togogenome.org/gene/510516:AO090023000585 ^@ http://purl.uniprot.org/uniprot/Q2UH48 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090011000879 ^@ http://purl.uniprot.org/uniprot/Q2TZE8 ^@ Similarity ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/510516:AO090102000021 ^@ http://purl.uniprot.org/uniprot/Q2UBC9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090020000572 ^@ http://purl.uniprot.org/uniprot/Q2U3Y1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090026000057 ^@ http://purl.uniprot.org/uniprot/Q2UFW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090003000476 ^@ http://purl.uniprot.org/uniprot/Q2ULB2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycosyl hydrolase 47 family.|||Ca(2+). Can also use Mg(2+), but with lower efficiency.|||Cytoplasmic vesicle lumen|||Involved in the maturation of Asn-linked oligosaccharides. Progressively trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).|||Monomer. http://togogenome.org/gene/510516:AO090005000083 ^@ http://purl.uniprot.org/uniprot/Q2UTB6 ^@ Similarity ^@ Belongs to the hexokinase family. http://togogenome.org/gene/510516:AO090003001503 ^@ http://purl.uniprot.org/uniprot/Q2UIS1 ^@ Similarity ^@ Belongs to the glycosyltransferase 32 family. http://togogenome.org/gene/510516:AO090011000297 ^@ http://purl.uniprot.org/uniprot/Q2U0U8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090023000485 ^@ http://purl.uniprot.org/uniprot/Q2UHD9 ^@ Similarity ^@ Belongs to the synaptobrevin family. http://togogenome.org/gene/510516:AO090023000488 ^@ http://purl.uniprot.org/uniprot/Q2UHD6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090103000406 ^@ http://purl.uniprot.org/uniprot/Q2TY36 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/510516:AO090026000391 ^@ http://purl.uniprot.org/uniprot/Q2UF14 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the DPH1/DPH2 family. DPH1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. http://togogenome.org/gene/510516:AO090003001391 ^@ http://purl.uniprot.org/uniprot/Q2UJ16 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 17 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/510516:AO090009000031 ^@ http://purl.uniprot.org/uniprot/Q2UV62 ^@ Function ^@ Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway. http://togogenome.org/gene/510516:AO090003001247 ^@ http://purl.uniprot.org/uniprot/Q2UJE8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the kynureninase family.|||Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/510516:AO090120000403 ^@ http://purl.uniprot.org/uniprot/Q2U630 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family. BET3 subfamily.|||Endoplasmic reticulum|||Part of the multisubunit TRAPP (transport protein particle) complex.|||Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.|||cis-Golgi network http://togogenome.org/gene/510516:AO090010000735 ^@ http://purl.uniprot.org/uniprot/Q2TW21 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090011000014 ^@ http://purl.uniprot.org/uniprot/Q2U1I7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090011000213 ^@ http://purl.uniprot.org/uniprot/Q2U113 ^@ Similarity ^@ Belongs to the NmrA-type oxidoreductase family. http://togogenome.org/gene/510516:AO090001000358 ^@ http://purl.uniprot.org/uniprot/Q2UNI0 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/510516:AO090012000929 ^@ http://purl.uniprot.org/uniprot/Q2UBN5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS12 family. http://togogenome.org/gene/510516:AO090023000862 ^@ http://purl.uniprot.org/uniprot/Q2UGF4 ^@ Similarity ^@ Belongs to the diphosphomevalonate decarboxylase family. http://togogenome.org/gene/510516:AO090023000147 ^@ http://purl.uniprot.org/uniprot/Q2UI90 ^@ Similarity ^@ Belongs to the asaB hydroxylase/desaturase family. http://togogenome.org/gene/510516:AO090003000849 ^@ http://purl.uniprot.org/uniprot/Q2UKD8 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/510516:AO090038000111 ^@ http://purl.uniprot.org/uniprot/Q2U3B2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M35 family.|||Binds 1 zinc ion per subunit.|||Secreted|||Secreted metalloproteinase that allows assimilation of proteinaceous substrates. Shows high activities on basic nuclear substrates such as histone and protamine. http://togogenome.org/gene/510516:AO090026000231 ^@ http://purl.uniprot.org/uniprot/Q2UFF2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/510516:AO090102000008 ^@ http://purl.uniprot.org/uniprot/Q2UBE1 ^@ Similarity ^@ Belongs to the PhyH family. http://togogenome.org/gene/510516:AO090005000479 ^@ http://purl.uniprot.org/uniprot/Q2USC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acyl-CoA oxidase family.|||Peroxisome http://togogenome.org/gene/510516:AO090026000323 ^@ http://purl.uniprot.org/uniprot/Q2UF71 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer. http://togogenome.org/gene/510516:AO090001000734 ^@ http://purl.uniprot.org/uniprot/Q2UMJ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATG22 family.|||Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation (By similarity).|||Vacuole membrane http://togogenome.org/gene/510516:AO090005001424 ^@ http://purl.uniprot.org/uniprot/Q2UQ16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MEF2 family.|||Nucleus http://togogenome.org/gene/510516:AO090009000697 ^@ http://purl.uniprot.org/uniprot/Q2UTK3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BMT2 family.|||S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA.|||nucleolus http://togogenome.org/gene/510516:AO090113000105 ^@ http://purl.uniprot.org/uniprot/Q2U5K7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/510516:AO090026000091 ^@ http://purl.uniprot.org/uniprot/Q2UFS7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000493 ^@ http://purl.uniprot.org/uniprot/Q2USB6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090124000061 ^@ http://purl.uniprot.org/uniprot/Q2U755 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/510516:AO090701000328 ^@ http://purl.uniprot.org/uniprot/Q2U8R0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005001008 ^@ http://purl.uniprot.org/uniprot/Q2UR20 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sideroflexin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/510516:AO090023000744 ^@ http://purl.uniprot.org/uniprot/Q2UGR5 ^@ Similarity ^@ Belongs to the flavin monoamine oxidase family. http://togogenome.org/gene/510516:AO090003000244 ^@ http://purl.uniprot.org/uniprot/Q2ULW3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/510516:AO090011000626 ^@ http://purl.uniprot.org/uniprot/Q2U017 ^@ Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||P1 and P2 exist as dimers at the large ribosomal subunit. http://togogenome.org/gene/510516:AO090003000282 ^@ http://purl.uniprot.org/uniprot/Q2ULT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat NOL10/ENP2 family.|||nucleolus http://togogenome.org/gene/510516:AO090113000029 ^@ http://purl.uniprot.org/uniprot/Q2U5S4 ^@ Function ^@ Gamma-glutamyltransferase. http://togogenome.org/gene/510516:AO090003001178 ^@ http://purl.uniprot.org/uniprot/Q2UJK2 ^@ Similarity ^@ Belongs to the RMD1/sif2 family. http://togogenome.org/gene/510516:AO090005001529 ^@ http://purl.uniprot.org/uniprot/Q2UPS4 ^@ Similarity ^@ Belongs to the NmrA-type oxidoreductase family. http://togogenome.org/gene/510516:AO090038000631 ^@ http://purl.uniprot.org/uniprot/Q86ZV0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Xylitol dehydrogenase which catalyzes the conversion of xylitol to D-xylulose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway. http://togogenome.org/gene/510516:AO090005001257 ^@ http://purl.uniprot.org/uniprot/Q2UQG6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the very long-chain fatty acids dehydratase HACD family.|||Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/510516:AO090102000148 ^@ http://purl.uniprot.org/uniprot/Q2UB18 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090020000676 ^@ http://purl.uniprot.org/uniprot/Q2U3P5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family.|||Binds 1 or 2 Zn(2+) ions per subunit.|||Xylitol dehydrogenase which catalyzes the conversion of xylitol to D-xylulose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway. http://togogenome.org/gene/510516:AO090023000315 ^@ http://purl.uniprot.org/uniprot/Q2UHT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.|||nucleolus http://togogenome.org/gene/510516:AO090005000668 ^@ http://purl.uniprot.org/uniprot/Q2URW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RPF2 family.|||nucleolus http://togogenome.org/gene/510516:AO090005000103 ^@ http://purl.uniprot.org/uniprot/Q2UT98 ^@ Cofactor|||PTM|||Similarity ^@ Belongs to the copper/topaquinone oxidase family.|||Contains 1 topaquinone per subunit.|||Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. http://togogenome.org/gene/510516:AO090038000414 ^@ http://purl.uniprot.org/uniprot/Q2U2L1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090023000798 ^@ http://purl.uniprot.org/uniprot/Q2UGL4 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL5 family.|||Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. http://togogenome.org/gene/510516:AO090003000746 ^@ http://purl.uniprot.org/uniprot/P57749 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible interconversion of glucose 1-phosphate and glucose 6-phosphate. Key enzyme in hexose metabolism. The reverse reaction is an essential step for biosynthesis because glucose 1-phosphate is the starting point for the synthesis of UDP-glucose, which acts as a precursor for the synthesis of oligosaccharides and trehalose.|||Cytoplasm http://togogenome.org/gene/510516:AO090005001590 ^@ http://purl.uniprot.org/uniprot/Q2UPM0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit F family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/510516:AO090009000296 ^@ http://purl.uniprot.org/uniprot/Q2UUJ0 ^@ Similarity ^@ Belongs to the SMC family. RAD50 subfamily. http://togogenome.org/gene/510516:AO090009000700 ^@ http://purl.uniprot.org/uniprot/Q2UTK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BUD31 (G10) family.|||Nucleus http://togogenome.org/gene/510516:AO090026000140 ^@ http://purl.uniprot.org/uniprot/Q2UFN1 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/510516:AO090003000061 ^@ http://purl.uniprot.org/uniprot/Q2UMB8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 18 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/510516:AO090138000204 ^@ http://purl.uniprot.org/uniprot/Q2U1K1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 1 family.|||Secreted http://togogenome.org/gene/510516:AO090026000494 ^@ http://purl.uniprot.org/uniprot/Q2UET2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090701000554 ^@ http://purl.uniprot.org/uniprot/Q2U863 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/510516:AO090003000804 ^@ http://purl.uniprot.org/uniprot/Q2UKH7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat TRM82 family.|||Forms a heterodimer with the catalytic subunit trm8.|||Nucleus|||Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. http://togogenome.org/gene/510516:AO090005001427 ^@ http://purl.uniprot.org/uniprot/Q2UQ13 ^@ Function ^@ Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis. http://togogenome.org/gene/510516:AO090011000889 ^@ http://purl.uniprot.org/uniprot/Q2TZE1 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/510516:AO090009000465 ^@ http://purl.uniprot.org/uniprot/Q2UU45 ^@ Similarity ^@ Belongs to the NmrA-type oxidoreductase family. http://togogenome.org/gene/510516:AO090020000164 ^@ http://purl.uniprot.org/uniprot/Q2U4X4 ^@ Similarity ^@ Belongs to the nucleosome assembly protein (NAP) family. http://togogenome.org/gene/510516:AO090102000640 ^@ http://purl.uniprot.org/uniprot/Q2U9W3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTF2H2 family.|||Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.|||Nucleus http://togogenome.org/gene/510516:AO090701000070 ^@ http://purl.uniprot.org/uniprot/Q2U9D6 ^@ Similarity ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family. http://togogenome.org/gene/510516:AO090003000943 ^@ http://purl.uniprot.org/uniprot/Q2UK58 ^@ Function|||Similarity ^@ Belongs to the 3-oxoacid CoA-transferase family.|||Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. http://togogenome.org/gene/510516:AO090701000115 ^@ http://purl.uniprot.org/uniprot/Q2U9A0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.|||Membrane http://togogenome.org/gene/510516:AO090009000634 ^@ http://purl.uniprot.org/uniprot/Q2UTQ7 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/510516:AO090003001359 ^@ http://purl.uniprot.org/uniprot/Q2UJ48 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/510516:AO090003000606 ^@ http://purl.uniprot.org/uniprot/Q2UKZ7 ^@ Similarity ^@ Belongs to the TFIIB family. http://togogenome.org/gene/510516:AO090012000971 ^@ http://purl.uniprot.org/uniprot/Q2UBJ7 ^@ Similarity ^@ Belongs to the RNase H family. http://togogenome.org/gene/510516:AO090103000278 ^@ http://purl.uniprot.org/uniprot/Q2TYE8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090113000178 ^@ http://purl.uniprot.org/uniprot/Q2U5E5 ^@ Similarity ^@ Belongs to the Necrosis inducing protein (NPP1) family. http://togogenome.org/gene/510516:AO090012000175 ^@ http://purl.uniprot.org/uniprot/Q2UDH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the actin family.|||Nucleus http://togogenome.org/gene/510516:AO090005001640 ^@ http://purl.uniprot.org/uniprot/Q2UPH5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.|||Belongs to the SPC25 family.|||Component of the NDC80 complex, which consists of ndc80, nuf2, spc24 and spc25.|||Nucleus|||kinetochore http://togogenome.org/gene/510516:AO090005001083 ^@ http://purl.uniprot.org/uniprot/Q2UQV8 ^@ Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. http://togogenome.org/gene/510516:AO090038000264 ^@ http://purl.uniprot.org/uniprot/Q2U2Y9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Cell membrane|||Integral membrane transporter that imports quinic acid to be catabolized as a carbon source.|||Interacts with creB.|||Ubiquitinated. Deubiquitinated by creB, probably to control its activity or amount. http://togogenome.org/gene/510516:AO090005001620 ^@ http://purl.uniprot.org/uniprot/Q2UPJ2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.|||Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/510516:AO090026000356 ^@ http://purl.uniprot.org/uniprot/Q2UF43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ferredoxin--NADP reductase type 1 family.|||Mitochondrion http://togogenome.org/gene/510516:AO090012000717 ^@ http://purl.uniprot.org/uniprot/Q2UC68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DASH complex ASK1 family.|||Nucleus|||kinetochore|||spindle http://togogenome.org/gene/510516:AO090010000035 ^@ http://purl.uniprot.org/uniprot/Q2TXR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090103000338 ^@ http://purl.uniprot.org/uniprot/Q2TY95 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family. http://togogenome.org/gene/510516:AO090012001026 ^@ http://purl.uniprot.org/uniprot/Q2UBE9 ^@ Similarity ^@ Belongs to the CDC50/LEM3 family. http://togogenome.org/gene/510516:AO090701000756 ^@ http://purl.uniprot.org/uniprot/Q2U7P5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/510516:AO090038000624 ^@ http://purl.uniprot.org/uniprot/Q2U230 ^@ Similarity ^@ Belongs to the OSBP family. http://togogenome.org/gene/510516:AO090138000037 ^@ http://purl.uniprot.org/uniprot/Q2U1Z5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000940 ^@ http://purl.uniprot.org/uniprot/Q2UR74 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090010000672 ^@ http://purl.uniprot.org/uniprot/Q2TW77 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090012000394 ^@ http://purl.uniprot.org/uniprot/Q2UCY8 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/510516:AO090012000193 ^@ http://purl.uniprot.org/uniprot/Q2UDF5 ^@ Similarity ^@ Belongs to the UreD family. http://togogenome.org/gene/510516:AO090005001346 ^@ http://purl.uniprot.org/uniprot/Q2UQ91 ^@ Similarity ^@ Belongs to the TBCC family. http://togogenome.org/gene/510516:AO090701000282 ^@ http://purl.uniprot.org/uniprot/Q2U8V1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090038000229 ^@ http://purl.uniprot.org/uniprot/Q2U319 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/510516:AO090120000404 ^@ http://purl.uniprot.org/uniprot/Q2U629 ^@ Similarity ^@ Belongs to the NAD kinase family. http://togogenome.org/gene/510516:AO090001000577 ^@ http://purl.uniprot.org/uniprot/Q2UMX9 ^@ Similarity ^@ Belongs to the Luc7 family. http://togogenome.org/gene/510516:AO090009000123 ^@ http://purl.uniprot.org/uniprot/Q2UUY5 ^@ Similarity|||Subunit ^@ Belongs to the TPP enzyme family.|||Homotetramer. http://togogenome.org/gene/510516:AO090102000477 ^@ http://purl.uniprot.org/uniprot/Q2UAA4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090026000830 ^@ http://purl.uniprot.org/uniprot/Q2UDY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/510516:AO090020000493 ^@ http://purl.uniprot.org/uniprot/Q2U450 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/510516:AO090012000551 ^@ http://purl.uniprot.org/uniprot/Q2UCK3 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase II family. http://togogenome.org/gene/510516:AO090003000356 ^@ http://purl.uniprot.org/uniprot/Q2ULM1 ^@ Cofactor|||PTM|||Similarity ^@ Belongs to the copper/topaquinone oxidase family.|||Contains 1 topaquinone per subunit.|||Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. http://togogenome.org/gene/510516:AO090020000635 ^@ http://purl.uniprot.org/uniprot/Q2U3S7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family.|||Binds 1 or 2 Zn(2+) ions per subunit.|||Xylitol dehydrogenase which catalyzes the conversion of xylitol to D-xylulose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway. http://togogenome.org/gene/510516:AO090020000436 ^@ http://purl.uniprot.org/uniprot/Q2U492 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 17 family.|||Cell membrane|||Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan (By similarity). http://togogenome.org/gene/510516:AO090026000650 ^@ http://purl.uniprot.org/uniprot/Q2UEE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/510516:AO090103000232 ^@ http://purl.uniprot.org/uniprot/Q2TYI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PA-phosphatase related phosphoesterase family.|||Membrane http://togogenome.org/gene/510516:AO090023000795 ^@ http://purl.uniprot.org/uniprot/Q2UGL7 ^@ Similarity ^@ Belongs to the amino acid/polyamine transporter 2 family. http://togogenome.org/gene/510516:AO090103000026 ^@ http://purl.uniprot.org/uniprot/Q2TZ11 ^@ Similarity ^@ Belongs to the peptidase S10 family. http://togogenome.org/gene/510516:AO090120000098 ^@ http://purl.uniprot.org/uniprot/Q2U6U1 ^@ Similarity ^@ Belongs to the Rab GDI family. http://togogenome.org/gene/510516:AO090010000358 ^@ http://purl.uniprot.org/uniprot/Q2TWY7 ^@ Similarity ^@ Belongs to the PhyH family. http://togogenome.org/gene/510516:AO090026000530 ^@ http://purl.uniprot.org/uniprot/Q2UEQ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090026000492 ^@ http://purl.uniprot.org/uniprot/Q2UET3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.|||Endoplasmic reticulum membrane http://togogenome.org/gene/510516:AO090023000226 ^@ http://purl.uniprot.org/uniprot/Q2UI17 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/510516:AO090011000415 ^@ http://purl.uniprot.org/uniprot/Q2U0J6 ^@ Disruption Phenotype|||Function|||Similarity|||Subcellular Location Annotation ^@ Abolishes the production of heptelidic acid.|||Belongs to the cytochrome P450 family.|||Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of heptelidic acid (HA), a sesquiterpene lactone that acts as an inhibitor of glyceraldehyde-3-phosphatedehydrogenase (GAPDH) and a growth inhibitor of the salt-tolerant lactic acid bacteria in soy sauce brewing.|||Membrane http://togogenome.org/gene/510516:AO090012000841 ^@ http://purl.uniprot.org/uniprot/Q2UBW0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HIR3 family.|||Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation.|||Nucleus http://togogenome.org/gene/510516:AO090003000879 ^@ http://purl.uniprot.org/uniprot/Q2UKB4 ^@ Cofactor|||PTM|||Similarity ^@ Binds 2 nickel ions per subunit.|||Carbamylation allows a single lysine to coordinate two nickel ions.|||In the C-terminal section; belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. http://togogenome.org/gene/510516:AO090023000951 ^@ http://purl.uniprot.org/uniprot/Q2UG74 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/510516:AO090120000273 ^@ http://purl.uniprot.org/uniprot/Q2U6E2 ^@ Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family. http://togogenome.org/gene/510516:AO090003000602 ^@ http://purl.uniprot.org/uniprot/Q2UL01 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090009000196 ^@ http://purl.uniprot.org/uniprot/Q2UUS5 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/510516:AO090023000646 ^@ http://purl.uniprot.org/uniprot/Q2UGZ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090701000129 ^@ http://purl.uniprot.org/uniprot/Q2U988 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDC123 family.|||Cytoplasm|||Regulates the cell cycle in a nutrient dependent manner. http://togogenome.org/gene/510516:AO090012000489 ^@ http://purl.uniprot.org/uniprot/Q2UCQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 22 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/510516:AO090010000399 ^@ http://purl.uniprot.org/uniprot/Q2TWV6 ^@ PTM|||Similarity ^@ Belongs to the eIF-5A family.|||eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group. http://togogenome.org/gene/510516:AO090138000044 ^@ http://purl.uniprot.org/uniprot/Q2U1Y8 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/510516:AO090009000284 ^@ http://purl.uniprot.org/uniprot/Q2UUK2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP23 family.|||Golgi apparatus membrane|||Golgi membrane protein involved in vesicular trafficking. http://togogenome.org/gene/510516:AO090023000671 ^@ http://purl.uniprot.org/uniprot/Q2UGX6 ^@ Function|||Similarity ^@ Belongs to the glucose-6-phosphate 1-epimerase family.|||Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P). http://togogenome.org/gene/510516:AO090023000809 ^@ http://purl.uniprot.org/uniprot/Q2UGK3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ ATP-binding RNA helicase involved in translation initiation. Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes (By similarity).|||Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.|||Cytoplasm|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/510516:AO090005001594 ^@ http://purl.uniprot.org/uniprot/Q2UPL6 ^@ Similarity ^@ Belongs to the cytidylyltransferase family. http://togogenome.org/gene/510516:AO090003000920 ^@ http://purl.uniprot.org/uniprot/Q2UK79 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090001000328 ^@ http://purl.uniprot.org/uniprot/Q2UNK4 ^@ Similarity ^@ Belongs to the IF-3 family. http://togogenome.org/gene/510516:AO090012000441 ^@ http://purl.uniprot.org/uniprot/Q2UCU7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090102000480 ^@ http://purl.uniprot.org/uniprot/Q2UAA1 ^@ Similarity ^@ Belongs to the Cyclase 1 superfamily. http://togogenome.org/gene/510516:AO090023000153 ^@ http://purl.uniprot.org/uniprot/Q2UI86 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. http://togogenome.org/gene/510516:AO090206000047 ^@ http://purl.uniprot.org/uniprot/Q2PIV5 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL13 family. http://togogenome.org/gene/510516:AO090003001142 ^@ http://purl.uniprot.org/uniprot/Q2UJN2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RuvB family.|||DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.|||Nucleus http://togogenome.org/gene/510516:AO090023000793 ^@ http://purl.uniprot.org/uniprot/Q2UGL9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Mevalonate kinase subfamily.|||Cytoplasm|||Mevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway. The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins. http://togogenome.org/gene/510516:AO090701000647 ^@ http://purl.uniprot.org/uniprot/Q2U7Y7 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090026000676 ^@ http://purl.uniprot.org/uniprot/Q2UEC4 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/510516:AO090023001003 ^@ http://purl.uniprot.org/uniprot/Q2UG27 ^@ Similarity ^@ Belongs to the cytidylyltransferase family. http://togogenome.org/gene/510516:AO090020000468 ^@ http://purl.uniprot.org/uniprot/Q2U468 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DDOST 48 kDa subunit family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). http://togogenome.org/gene/510516:AO090012000797 ^@ http://purl.uniprot.org/uniprot/Q2UC03 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase V0D/AC39 subunit family.|||Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/510516:AO090001000458 ^@ http://purl.uniprot.org/uniprot/Q2UN90 ^@ Similarity ^@ Belongs to the SURF6 family. http://togogenome.org/gene/510516:AO090026000257 ^@ http://purl.uniprot.org/uniprot/Q2UFC7 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/510516:AO090011000798 ^@ http://purl.uniprot.org/uniprot/Q2TZM2 ^@ Similarity ^@ Belongs to the eIF-2-beta/eIF-5 family. http://togogenome.org/gene/510516:AO090009000424 ^@ http://purl.uniprot.org/uniprot/Q2UU78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I NDUFB11 subunit family.|||Membrane http://togogenome.org/gene/510516:AO090003000589 ^@ http://purl.uniprot.org/uniprot/Q2UL12 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycosyltransferase 2 family.|||Component of the dolichol-phosphate mannose (DPM) synthase complex.|||Endoplasmic reticulum|||Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. http://togogenome.org/gene/510516:AO090003000582 ^@ http://purl.uniprot.org/uniprot/Q2UL18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL40 family.|||Mitochondrion http://togogenome.org/gene/510516:AO090026000394 ^@ http://purl.uniprot.org/uniprot/Q2UF11 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.|||Mitochondrion matrix http://togogenome.org/gene/510516:AO090038000131 ^@ http://purl.uniprot.org/uniprot/Q2U395 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/510516:AO090012000340 ^@ http://purl.uniprot.org/uniprot/Q2UD32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-93 family.|||Membrane http://togogenome.org/gene/510516:AO090001000415 ^@ http://purl.uniprot.org/uniprot/Q2UND0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090001000519 ^@ http://purl.uniprot.org/uniprot/Q2UN37 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.|||Binds to histones H3 and H4.|||Inhibited by both FK506 and rapamycin.|||Nucleus|||PPIase that acts as a histone chaperone. Histone proline isomerase that increases the rate of cis-trans isomerization at prolines on the histone H3 N-terminal tail. Proline isomerization influences H3 methylation thereby regulating gene expression. http://togogenome.org/gene/510516:AO090120000386 ^@ http://purl.uniprot.org/uniprot/Q2U645 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNF2/RAD54 helicase family.|||Nucleus http://togogenome.org/gene/510516:AO090001000332 ^@ http://purl.uniprot.org/uniprot/Q2UNK1 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/510516:AO090005000775 ^@ http://purl.uniprot.org/uniprot/Q2URL9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090138000040 ^@ http://purl.uniprot.org/uniprot/Q2U1Z2 ^@ Similarity ^@ Belongs to the MSOX/MTOX family. http://togogenome.org/gene/510516:AO090012000274 ^@ http://purl.uniprot.org/uniprot/Q2UD87 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase proteolipid subunit family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''. http://togogenome.org/gene/510516:AO090026000726 ^@ http://purl.uniprot.org/uniprot/Q2UE83 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/510516:AO090102000578 ^@ http://purl.uniprot.org/uniprot/Q2UA19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF6 family.|||Nucleus http://togogenome.org/gene/510516:AO090102000317 ^@ http://purl.uniprot.org/uniprot/Q2UAN3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090120000484 ^@ http://purl.uniprot.org/uniprot/Q2U5W4 ^@ Subcellular Location Annotation ^@ Mitochondrion outer membrane http://togogenome.org/gene/510516:AO090003000411 ^@ http://purl.uniprot.org/uniprot/Q2ULH4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.|||Homodimer.|||Mitochondrion inner membrane|||Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating the ATP-dependent export of Fe/S cluster precursors synthesized by nfs1 and other mitochondrial proteins (By similarity). Hydrolyzes ATP (By similarity). Binds glutathione and may function by transporting a glutathione-conjugated iron-sulfur compound (By similarity). http://togogenome.org/gene/510516:AO090026000703 ^@ http://purl.uniprot.org/uniprot/Q2UEA1 ^@ Similarity ^@ Belongs to the adaptor complexes large subunit family. http://togogenome.org/gene/510516:AO090003000569 ^@ http://purl.uniprot.org/uniprot/Q2UL31 ^@ Function|||Subcellular Location Annotation ^@ Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.|||Nucleus http://togogenome.org/gene/510516:AO090020000679 ^@ http://purl.uniprot.org/uniprot/Q2U3P3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090026000807 ^@ http://purl.uniprot.org/uniprot/Q2UE07 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NFYA/HAP2 subunit family.|||Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.|||Heterotrimer.|||Nucleus http://togogenome.org/gene/510516:AO090023000303 ^@ http://purl.uniprot.org/uniprot/Q2UHU9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the F-actin-capping protein alpha subunit family.|||F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).|||Heterodimer of an alpha and a beta subunit.|||cytoskeleton http://togogenome.org/gene/510516:AO090011000449 ^@ http://purl.uniprot.org/uniprot/Q2U0G5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the chitin synthase family.|||Cell membrane|||Membrane|||Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer. http://togogenome.org/gene/510516:AO090009000715 ^@ http://purl.uniprot.org/uniprot/Q2UTI8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS1 family.|||Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).|||Cytoplasm http://togogenome.org/gene/510516:AO090005000927 ^@ http://purl.uniprot.org/uniprot/Q2UR85 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 76 family. http://togogenome.org/gene/510516:AO090012000940 ^@ http://purl.uniprot.org/uniprot/Q2UBM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat WDR55 family.|||nucleolus http://togogenome.org/gene/510516:AO090003001350 ^@ http://purl.uniprot.org/uniprot/Q2UJ55 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/510516:AO090701000225 ^@ http://purl.uniprot.org/uniprot/Q2U903 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ETF beta-subunit/FixA family.|||Binds 1 AMP per subunit.|||Binds 1 FAD per dimer.|||Heterodimer of an alpha and a beta subunit.|||Mitochondrion matrix|||The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/510516:AO090020000351 ^@ http://purl.uniprot.org/uniprot/Q2U4G6 ^@ Similarity ^@ Belongs to the peptidase S10 family. http://togogenome.org/gene/510516:AO090001000110 ^@ http://purl.uniprot.org/uniprot/Q2UP52 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/510516:AO090010000168 ^@ http://purl.uniprot.org/uniprot/Q2TXF3 ^@ Cofactor|||Function|||Similarity ^@ Alpha-ketoglutarate-dependent dioxygenase; part of the gene cluster that mediates the biosynthesis of oryzines, natural products with an unusual maleidride backbone (PubMed:30104550). The two subunits of the fungal fatty acid synthase oryfasA and oryfasB probably form octenoic acid (Probable). This fatty acid is most likely activated by the acyl-CoA ligase oryP to give octenyl-CoA before the citrate synthase-like protein oryE catalyzes condensation with oxaloacetate to form tricarboxylic acid (Probable). The next steps of the pathways are conjectural, but a favorite possible route has been proposed, beginning with decarboxylation and concomitant dehydration by the decarboxylase oryM, followed by tautomerization, which may lead to the production of a diene intermediate (Probable). Reduction of this diene intermediate could give the known metabolite piliformic acid (Probable). On the pathway to oryzine B and oryzine A, however, hydroxylation of the diene by the alpha-ketoglutarate-dependent dioxygenase oryG and lactonisation by the lactonohydrolases oryH or oryL could give oryzine B directly (Probable). Finally, enoyl reduction by the dehydrogenase oryD would then convert oryzine B into oryzine A (Probable).|||Belongs to the TfdA dioxygenase family.|||Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/510516:AO090003000044 ^@ http://purl.uniprot.org/uniprot/Q2UMD3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090011000764 ^@ http://purl.uniprot.org/uniprot/Q2TZQ3 ^@ Similarity ^@ Belongs to the chaperonin (HSP60) family. http://togogenome.org/gene/510516:AO090026000270 ^@ http://purl.uniprot.org/uniprot/Q2UFB5 ^@ Similarity ^@ Belongs to the RNase PH family. http://togogenome.org/gene/510516:AO090005000761 ^@ http://purl.uniprot.org/uniprot/Q2URM8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL11 family. http://togogenome.org/gene/510516:AO090003000520 ^@ http://purl.uniprot.org/uniprot/Q2UL76 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090003000364 ^@ http://purl.uniprot.org/uniprot/Q2ULL4 ^@ Similarity ^@ Belongs to the eIF-2B gamma/epsilon subunits family. http://togogenome.org/gene/510516:AO090038000544 ^@ http://purl.uniprot.org/uniprot/Q2U2A0 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/510516:AO090026000193 ^@ http://purl.uniprot.org/uniprot/Q2UFI6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003001556 ^@ http://purl.uniprot.org/uniprot/Q2UIM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090009000701 ^@ http://purl.uniprot.org/uniprot/Q2UTK0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090120000176 ^@ http://purl.uniprot.org/uniprot/Q2U6M4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090026000321 ^@ http://purl.uniprot.org/uniprot/Q2UF72 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||Membrane|||Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer. http://togogenome.org/gene/510516:AO090003000759 ^@ http://purl.uniprot.org/uniprot/Q2UKL5 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/510516:AO090120000232 ^@ http://purl.uniprot.org/uniprot/Q2U6H7 ^@ Similarity ^@ Belongs to the peptidase S10 family. http://togogenome.org/gene/510516:AO090012000818 ^@ http://purl.uniprot.org/uniprot/Q2UBY2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090003000816 ^@ http://purl.uniprot.org/uniprot/Q2UKG6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit A family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm|||RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. http://togogenome.org/gene/510516:AO090020000367 ^@ http://purl.uniprot.org/uniprot/Q2U4F3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090102000636 ^@ http://purl.uniprot.org/uniprot/Q2U9W7 ^@ Similarity ^@ Belongs to the WD repeat LST8 family. http://togogenome.org/gene/510516:AO090020000623 ^@ http://purl.uniprot.org/uniprot/Q2U3T7 ^@ Similarity|||Subunit ^@ Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.|||Heterodimer of a catalytic heavy chain and a regulatory light chain. http://togogenome.org/gene/510516:AO090011000504 ^@ http://purl.uniprot.org/uniprot/Q2U0B7 ^@ Similarity|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.|||Homotetramer. http://togogenome.org/gene/510516:AO090103000328 ^@ http://purl.uniprot.org/uniprot/Q2TYA5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Homodimer. http://togogenome.org/gene/510516:AO090003000536 ^@ http://purl.uniprot.org/uniprot/Q2UL62 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090003001141 ^@ http://purl.uniprot.org/uniprot/Q2UJN3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/510516:AO090026000444 ^@ http://purl.uniprot.org/uniprot/Q2UEX1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HAT1 family.|||Catalytic component of the histone acetylase B (HAT-B) complex. Acetylates 'Lys-12' of histone H4 which is required for telomeric silencing. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair.|||Component of the HAT-B complex composed of at least hat1 and hat2. The HAT-B complex binds to histone H4 tail.|||Cytoplasm|||Nucleus http://togogenome.org/gene/510516:AO090701000097 ^@ http://purl.uniprot.org/uniprot/Q2U9B5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 divalent metal cation per subunit.|||Component of the EKC/KEOPS complex composed of at least bud32, cgi121, gon7, kae1 and pcc1; the whole complex dimerizes.|||Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.|||Cytoplasm|||Nucleus http://togogenome.org/gene/510516:AO090009000055 ^@ http://purl.uniprot.org/uniprot/Q2UV41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.|||Membrane http://togogenome.org/gene/510516:AO090003000038 ^@ http://purl.uniprot.org/uniprot/Q2UMD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA1 family.|||Membrane http://togogenome.org/gene/510516:AO090001000216 ^@ http://purl.uniprot.org/uniprot/Q2UNV6 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/510516:AO090011000653 ^@ http://purl.uniprot.org/uniprot/Q2TZZ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TIM21 family.|||Component of the TIM23 complex.|||Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090113000006 ^@ http://purl.uniprot.org/uniprot/Q2U5U2 ^@ Function|||Similarity ^@ Belongs to the VPS16 family.|||Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. http://togogenome.org/gene/510516:AO090001000574 ^@ http://purl.uniprot.org/uniprot/Q2UMY2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. http://togogenome.org/gene/510516:AO090003001393 ^@ http://purl.uniprot.org/uniprot/Q2UJ14 ^@ Similarity ^@ Belongs to the PrpF family. http://togogenome.org/gene/510516:AO090003001498 ^@ http://purl.uniprot.org/uniprot/Q2UIS5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/510516:AO090120000493 ^@ http://purl.uniprot.org/uniprot/Q9HGY8 ^@ Similarity|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Homodimer. http://togogenome.org/gene/510516:AO090005001206 ^@ http://purl.uniprot.org/uniprot/Q2UQK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATG27 family.|||Cytoplasmic vesicle membrane|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/510516:AO090003000545 ^@ http://purl.uniprot.org/uniprot/Q2UL53 ^@ Cofactor|||Function ^@ Accepts electrons from ETF and reduces ubiquinone.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/510516:AO090012000588 ^@ http://purl.uniprot.org/uniprot/Q2UCH3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090001000194 ^@ http://purl.uniprot.org/uniprot/Q2UNX4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family.|||Nucleus|||Putative transcription factor. http://togogenome.org/gene/510516:AO090010000524 ^@ http://purl.uniprot.org/uniprot/Q2TWK3 ^@ Similarity ^@ Belongs to the amino acid/polyamine transporter 2 family. http://togogenome.org/gene/510516:AO090012000923 ^@ http://purl.uniprot.org/uniprot/Q2UBP1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RSP5/NEDD4 family.|||Cytoplasm|||E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Probably involved in the regulatory network controlling carbon source utilization.|||Interacts with creD. http://togogenome.org/gene/510516:AO090003000004 ^@ http://purl.uniprot.org/uniprot/Q2UMH1 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/510516:AO090023000432 ^@ http://purl.uniprot.org/uniprot/Q2UHI6 ^@ Similarity ^@ Belongs to the PheA/TfdB FAD monooxygenase family. http://togogenome.org/gene/510516:AO090001000101 ^@ http://purl.uniprot.org/uniprot/Q2UP60 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/510516:AO090003001222 ^@ http://purl.uniprot.org/uniprot/Q2UJH0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090010000332 ^@ http://purl.uniprot.org/uniprot/Q2TX10 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090020000390 ^@ http://purl.uniprot.org/uniprot/Q2U4D1 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/510516:AO090026000369 ^@ http://purl.uniprot.org/uniprot/Q2UF33 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRG9 family.|||Mitochondrion|||Required for respiratory activity and maintenance and expression of the mitochondrial genome. http://togogenome.org/gene/510516:AO090005001360 ^@ http://purl.uniprot.org/uniprot/Q2UQ78 ^@ Similarity ^@ Belongs to the eukaryotic-type primase small subunit family. http://togogenome.org/gene/510516:AO090102000584 ^@ http://purl.uniprot.org/uniprot/Q2UA13 ^@ Similarity ^@ Belongs to the CoA-transferase III family. http://togogenome.org/gene/510516:AO090023000824 ^@ http://purl.uniprot.org/uniprot/Q2UGI9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. http://togogenome.org/gene/510516:AO090009000674 ^@ http://purl.uniprot.org/uniprot/Q2UTM4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. http://togogenome.org/gene/510516:AO090023000465 ^@ http://purl.uniprot.org/uniprot/Q2UHF7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090011000425 ^@ http://purl.uniprot.org/uniprot/Q2U0I6 ^@ Similarity ^@ Belongs to the PhyH family. http://togogenome.org/gene/510516:AO090012000174 ^@ http://purl.uniprot.org/uniprot/Q2UDH1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090001000323 ^@ http://purl.uniprot.org/uniprot/Q2UNK9 ^@ Similarity ^@ Belongs to the tpcK family. http://togogenome.org/gene/510516:AO090012000886 ^@ http://purl.uniprot.org/uniprot/Q2UBS4 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/510516:AO090005001477 ^@ http://purl.uniprot.org/uniprot/Q2UPW9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPB4 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/510516:AO090010000342 ^@ http://purl.uniprot.org/uniprot/Q2TX01 ^@ Similarity ^@ Belongs to the NmrA-type oxidoreductase family. http://togogenome.org/gene/510516:AO090003000769 ^@ http://purl.uniprot.org/uniprot/Q2UKK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||Membrane http://togogenome.org/gene/510516:AO090005001447 ^@ http://purl.uniprot.org/uniprot/Q2UPZ7 ^@ Activity Regulation|||Cofactor|||PTM|||Similarity|||Subunit ^@ Belongs to the peptidase M18 family.|||Binds 2 Zn(2+) ions per subunit.|||Inhibited by zinc. Stimulated by calcium and bacitracin.|||Tetrahedron-shaped homododecamer built from six homodimers.|||The N-terminus is blocked. http://togogenome.org/gene/510516:AO090001000485 ^@ http://purl.uniprot.org/uniprot/Q2UN68 ^@ Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||P1 and P2 exist as dimers at the large ribosomal subunit. http://togogenome.org/gene/510516:AO090026000443 ^@ http://purl.uniprot.org/uniprot/Q2UEX2 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/510516:AO090020000650 ^@ http://purl.uniprot.org/uniprot/Q2U3R5 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/510516:AO090701000344 ^@ http://purl.uniprot.org/uniprot/Q2U8P6 ^@ Similarity ^@ Belongs to the NUP family. http://togogenome.org/gene/510516:AO090166000064 ^@ http://purl.uniprot.org/uniprot/Q2U9Q0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003000384 ^@ http://purl.uniprot.org/uniprot/Q2ULJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20A family.|||Secreted http://togogenome.org/gene/510516:AO090010000333 ^@ http://purl.uniprot.org/uniprot/Q2TX09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Membrane http://togogenome.org/gene/510516:AO090701000290 ^@ http://purl.uniprot.org/uniprot/Q2U8U4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090011000455 ^@ http://purl.uniprot.org/uniprot/Q2U0F9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family.|||Cytoplasm http://togogenome.org/gene/510516:AO090005001065 ^@ http://purl.uniprot.org/uniprot/Q2UQX3 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/510516:AO090005001275 ^@ http://purl.uniprot.org/uniprot/Q2UQF2 ^@ Similarity ^@ Belongs to the UTP6 family. http://togogenome.org/gene/510516:AO090020000492 ^@ http://purl.uniprot.org/uniprot/Q2U451 ^@ Similarity ^@ Belongs to the AccD/PCCB family. http://togogenome.org/gene/510516:AO090003001170 ^@ http://purl.uniprot.org/uniprot/Q2UJK9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNU66/SART1 family.|||Nucleus http://togogenome.org/gene/510516:AO090005001344 ^@ http://purl.uniprot.org/uniprot/Q2UQ93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 16 family.|||Cell membrane|||Membrane http://togogenome.org/gene/510516:AO090026000524 ^@ http://purl.uniprot.org/uniprot/Q2UEQ5 ^@ Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate. http://togogenome.org/gene/510516:AO090001000037 ^@ http://purl.uniprot.org/uniprot/Q2UPB5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer.|||Thioredoxin reductase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411). The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411). One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411). After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411). In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411). Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411). http://togogenome.org/gene/510516:AO090026000585 ^@ http://purl.uniprot.org/uniprot/Q2UEK2 ^@ Disruption Phenotype|||Domain|||Function|||Induction|||Similarity ^@ Belongs to the NRP synthetase family.|||Expression is regulated by the secondary metabolite regulator cclA.|||Impairs the production of deacetyl astellolides A and B and leads to the accumulation of trihydroxy confertifolin.|||NRP synthetases are composed of discrete domains (adenylation (A), thiolation (T) or peptidyl carrier protein (PCP) and condensation (C) domains) which when grouped together are referred to as a single module. Each module is responsible for the recognition (via the A domain) and incorporation of a single amino acid into the growing peptide product. Thus, an NRP synthetase is generally composed of one or more modules and can terminate in a thioesterase domain (TE) that releases the newly synthesized peptide from the enzyme. Occasionally, epimerase (E) domains (responsible for L- to D- amino acid conversion) are present within the NRP synthetase. AsrA has the following single module architecture: A-T-C.|||Nonribosomal peptide synthetase; part of the gene cluster that mediates the biosynthesis of astellolides, drimane-type sesquiterpene esters that show antimicrobial, anti-inflammatory, and anti-tumor activities (PubMed:27628599). The first step in astellolide biosynthesis is performed by the sesquiterpene cyclase astC that catalyzes the formation of drimanyl pyrophosphate from farnesyl pyrophosphate (PubMed:27628599). Drimanyl pyrophosphate is then dephosphorylated by the sesquiterpene phosphatase astI to produce drimanyl monophosphate which is further dephosphorylated to drim-8-ene-11-ol by atsK (PubMed:27628599). Drim-8-ene-11-ol is converted to confertifolin, probably by the cytochrome P450 monooxygenase astD and/or the dehydrogenase astE (PubMed:27628599). The cytochrome P450 monooxygenases astB, astF and astJ then hydroxylate confertifolin at C6, C14, or C15 to form trihydroxy confertifolin (PubMed:27628599). The nonribosomal peptide synthetase astA catalyzes ester bond formation between trihydroxy contifolin and benzoic acid (BA) or 4-hydroxy benzoic acid (4HBA), leading to the formation of dideacetyl astellolides A and B, respectively (PubMed:27628599). Finally, the O-acetyltransferase astG converts dideacetyl astellolides A and B into deacetyl astellolides A and B (PubMed:27628599). http://togogenome.org/gene/510516:AO090701000324 ^@ http://purl.uniprot.org/uniprot/Q2U8R4 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/510516:AO090003001348 ^@ http://purl.uniprot.org/uniprot/Q2UJ57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||nucleolus http://togogenome.org/gene/510516:AO090023000256 ^@ http://purl.uniprot.org/uniprot/Q2UHY8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. http://togogenome.org/gene/510516:AO090103000195 ^@ http://purl.uniprot.org/uniprot/Q2TYL8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090023000288 ^@ http://purl.uniprot.org/uniprot/Q2UHW3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/510516:AO090166000048 ^@ http://purl.uniprot.org/uniprot/Q2U9R5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 3 family.|||Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.|||Secreted http://togogenome.org/gene/510516:AO090001000417 ^@ http://purl.uniprot.org/uniprot/Q2UNC8 ^@ Similarity ^@ Belongs to the proteasome subunit S9 family. http://togogenome.org/gene/510516:AO090003000417 ^@ http://purl.uniprot.org/uniprot/Q2ULG8 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/510516:AO090009000215 ^@ http://purl.uniprot.org/uniprot/Q2UUQ9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 37 family. http://togogenome.org/gene/510516:AO090026000510 ^@ http://purl.uniprot.org/uniprot/Q2UER8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KRR1 family.|||Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with MPP10, KRI1 and with ribosomal proteins RPS1A, RPS4A, RPS4B, RPS8A, RPS8B, RPS11A, RPS11B, RPS13, RPS24, RPS25, RPL4A, RPL7B, RPL8, RPL23, RPL25 and RPL28.|||Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.|||nucleolus http://togogenome.org/gene/510516:AO090010000156 ^@ http://purl.uniprot.org/uniprot/Q2TXG3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the fungal fatty acid synthetase subunit beta family.|||Fatty acid synthase beta subunit; part of the gene cluster that mediates the biosynthesis of oryzines, natural products with an unusual maleidride backbone (PubMed:30104550). The two subunits of the fungal fatty acid synthase oryfasA and oryfasB probably form octenoic acid (Probable). This fatty acid is most likely activated by the acyl-CoA ligase oryP to give octenyl-CoA before the citrate synthase-like protein oryE catalyzes condensation with oxaloacetate to form tricarboxylic acid (Probable). The next steps of the pathways are conjectural, but a favorite possible route has been proposed, beginning with decarboxylation and concomitant dehydration by the decarboxylase oryM, followed by tautomerization, which may lead to the production of a diene intermediate (Probable). Reduction of this diene intermediate could give the known metabolite piliformic acid (Probable). On the pathway to oryzine B and oryzine A, however, hydroxylation of the diene by the alpha-ketoglutarate-dependent dioxygenase oryG and lactonisation by the lactonohydrolases oryH or oryL could give oryzine B directly (Probable). Finally, enoyl reduction by the dehydrogenase oryD would then convert oryzine B into oryzine A (Probable).|||[Alpha(6)beta(6)] hexamers of two multifunctional subunits (alpha and beta). http://togogenome.org/gene/510516:AO090701000612 ^@ http://purl.uniprot.org/uniprot/Q2U813 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.|||cytoskeleton http://togogenome.org/gene/510516:AO090001000636 ^@ http://purl.uniprot.org/uniprot/Q2UMT0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003000438 ^@ http://purl.uniprot.org/uniprot/Q2ULE8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TFIIE beta subunit family.|||Nucleus|||Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.|||Tetramer of two alpha and two beta chains. http://togogenome.org/gene/510516:AO090011000295 ^@ http://purl.uniprot.org/uniprot/Q2U0V0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090026000329 ^@ http://purl.uniprot.org/uniprot/Q2UF66 ^@ Similarity ^@ Belongs to the RCAN family. http://togogenome.org/gene/510516:AO090038000411 ^@ http://purl.uniprot.org/uniprot/Q2U2L4 ^@ Similarity|||Subunit ^@ Associated with the spliceosome.|||Belongs to the crooked-neck family. http://togogenome.org/gene/510516:AO090120000279 ^@ http://purl.uniprot.org/uniprot/Q2U6E0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 16 family.|||Cell membrane|||Membrane http://togogenome.org/gene/510516:AO090010000007 ^@ http://purl.uniprot.org/uniprot/Q2TXU6 ^@ Similarity ^@ Belongs to the isochorismatase family.|||Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/510516:AO090020000212 ^@ http://purl.uniprot.org/uniprot/Q2U4T4 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/510516:AO090003000363 ^@ http://purl.uniprot.org/uniprot/Q2ULL5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090102000353 ^@ http://purl.uniprot.org/uniprot/Q2UAK1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity).|||Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.|||nucleolus http://togogenome.org/gene/510516:AO090010000034 ^@ http://purl.uniprot.org/uniprot/Q2TXS0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 3 family.|||Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.|||Secreted http://togogenome.org/gene/510516:AO090001000543 ^@ http://purl.uniprot.org/uniprot/Q2UN13 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090012000749 ^@ http://purl.uniprot.org/uniprot/Q2UC42 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pectinesterase family.|||Involved in maceration and soft-rotting of plant tissue.|||Secreted http://togogenome.org/gene/510516:AO090020000192 ^@ http://purl.uniprot.org/uniprot/Q2U4V2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090010000221 ^@ http://purl.uniprot.org/uniprot/Q2TXA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal/bacterial/fungal opsin family.|||Membrane http://togogenome.org/gene/510516:AO090010000406 ^@ http://purl.uniprot.org/uniprot/Q2TWU9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090001000599 ^@ http://purl.uniprot.org/uniprot/Q2UMW0 ^@ Similarity ^@ Belongs to the sirtuin family. Class I subfamily. http://togogenome.org/gene/510516:AO090003000534 ^@ http://purl.uniprot.org/uniprot/Q2UL64 ^@ Similarity|||Subunit ^@ Belongs to the cAMP-dependent kinase regulatory chain family.|||Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer. http://togogenome.org/gene/510516:AO090009000377 ^@ http://purl.uniprot.org/uniprot/Q2UUB9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS3 family. http://togogenome.org/gene/510516:AO090005000114 ^@ http://purl.uniprot.org/uniprot/Q2UT89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.|||Membrane http://togogenome.org/gene/510516:AO090001000325 ^@ http://purl.uniprot.org/uniprot/Q2UNK7 ^@ Similarity ^@ Belongs to the Cyclase 1 superfamily. http://togogenome.org/gene/510516:AO090020000396 ^@ http://purl.uniprot.org/uniprot/Q2U4C6 ^@ Similarity ^@ Belongs to the CIA30 family. http://togogenome.org/gene/510516:AO090012000629 ^@ http://purl.uniprot.org/uniprot/Q2UCE1 ^@ Similarity|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Octamer of two non-identical subunits IDH1 and IDH2. http://togogenome.org/gene/510516:AO090005001400 ^@ http://purl.uniprot.org/uniprot/Q2UQ40 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 28 family.|||Secreted|||Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates. http://togogenome.org/gene/510516:AO090020000183 ^@ http://purl.uniprot.org/uniprot/Q2U4V9 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/510516:AO090005000806 ^@ http://purl.uniprot.org/uniprot/Q2URJ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the F-actin-capping protein beta subunit family.|||F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).|||Heterodimer of an alpha and a beta subunit.|||Nucleus|||cytoskeleton http://togogenome.org/gene/510516:AO090012000063 ^@ http://purl.uniprot.org/uniprot/Q2UDR6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090102000536 ^@ http://purl.uniprot.org/uniprot/Q2UA56 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/510516:AO090010000563 ^@ http://purl.uniprot.org/uniprot/Q2TWG8 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily. http://togogenome.org/gene/510516:AO090020000385 ^@ http://purl.uniprot.org/uniprot/Q2U4D6 ^@ Function|||Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.|||Nitrilase that hydrolyzes preferentially phenylacetonitrile, (R,S)-mandelonitrile, and 3-indolylacetonitrile. http://togogenome.org/gene/510516:AO090103000141 ^@ http://purl.uniprot.org/uniprot/Q2TYR4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 11 (cellulase G) family.|||Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.|||Secreted http://togogenome.org/gene/510516:AO090038000259 ^@ http://purl.uniprot.org/uniprot/Q2U2Z4 ^@ Similarity ^@ In the 2nd section; belongs to the type-I 3-dehydroquinase family.|||In the N-terminal section; belongs to the shikimate kinase family. http://togogenome.org/gene/510516:AO090026000603 ^@ http://purl.uniprot.org/uniprot/Q2UEI6 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily. http://togogenome.org/gene/510516:AO090011000320 ^@ http://purl.uniprot.org/uniprot/Q2U0S9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.|||Endoplasmic reticulum membrane|||Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity). http://togogenome.org/gene/510516:AO090103000407 ^@ http://purl.uniprot.org/uniprot/Q2TY35 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/510516:AO090026000531 ^@ http://purl.uniprot.org/uniprot/Q2UEP9 ^@ Similarity ^@ Belongs to the CDC73 family. http://togogenome.org/gene/510516:AO090010000706 ^@ http://purl.uniprot.org/uniprot/Q2TW49 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 3 family.|||Binds 1 Ca(2+) ion per subunit.|||Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090023000032 ^@ http://purl.uniprot.org/uniprot/Q2UIJ5 ^@ Similarity ^@ Belongs to the aegerolysin family. http://togogenome.org/gene/510516:AO090103000343 ^@ http://purl.uniprot.org/uniprot/Q2TY90 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/510516:AO090113000098 ^@ http://purl.uniprot.org/uniprot/Q2U5L4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090102000507 ^@ http://purl.uniprot.org/uniprot/Q2UA80 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associated with the spliceosome.|||Belongs to the SNW family.|||Involved in pre-mRNA splicing.|||Nucleus http://togogenome.org/gene/510516:AO090011000272 ^@ http://purl.uniprot.org/uniprot/Q2U0W7 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) per subunit.|||Homotetramer. http://togogenome.org/gene/510516:AO090010000224 ^@ http://purl.uniprot.org/uniprot/Q2TXA2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||May be involved in cellular response to stress. Required to maintain mitochondrial DNA (mtDNA) integrity and stability (By similarity).|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090020000418 ^@ http://purl.uniprot.org/uniprot/Q2U4A8 ^@ Similarity ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. http://togogenome.org/gene/510516:AO090701000403 ^@ http://purl.uniprot.org/uniprot/Q2U8K0 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/510516:AO090001000234 ^@ http://purl.uniprot.org/uniprot/Q2UNT9 ^@ Subcellular Location Annotation ^@ cytosol http://togogenome.org/gene/510516:AO090026000611 ^@ http://purl.uniprot.org/uniprot/Q2UEI0 ^@ Function|||Similarity ^@ Belongs to the type IA topoisomerase family.|||Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. http://togogenome.org/gene/510516:AO090009000430 ^@ http://purl.uniprot.org/uniprot/Q2UU72 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Forms a complex with trm82.|||Nucleus http://togogenome.org/gene/510516:AO090003000058 ^@ http://purl.uniprot.org/uniprot/Q2UMC1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20A family.|||Binds 2 Zn(2+) ions per subunit.|||Secreted http://togogenome.org/gene/510516:AO090020000373 ^@ http://purl.uniprot.org/uniprot/Q2U4E7 ^@ Similarity ^@ Belongs to the amidase family. http://togogenome.org/gene/510516:AO090003000750 ^@ http://purl.uniprot.org/uniprot/Q2UKM4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the WD repeat MET30/SCONB/SCON-2 family.|||Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.|||Component of the SCF(sconB) E3 ubiquitin ligase complex. http://togogenome.org/gene/510516:AO090012000248 ^@ http://purl.uniprot.org/uniprot/Q2UDA8 ^@ Similarity ^@ Belongs to the ubiquitin-activating E1 family. http://togogenome.org/gene/510516:AO090011000820 ^@ http://purl.uniprot.org/uniprot/Q2TZK3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090012000296 ^@ http://purl.uniprot.org/uniprot/Q2UD68 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005001407 ^@ http://purl.uniprot.org/uniprot/Q2UQ33 ^@ Function|||Similarity ^@ Belongs to the MBF1 family.|||Transcriptional coactivator that stimulates transcriptional activity by bridging regulatory proteins and TBP, thereby recruiting TBP to promoters occupied by DNA-binding regulators. http://togogenome.org/gene/510516:AO090005001472 ^@ http://purl.uniprot.org/uniprot/Q2UPX3 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/510516:AO090026000317 ^@ http://purl.uniprot.org/uniprot/Q2UF76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TDE1 family.|||Membrane http://togogenome.org/gene/510516:AO090005000037 ^@ http://purl.uniprot.org/uniprot/Q2UTF7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/510516:AO090026000771 ^@ http://purl.uniprot.org/uniprot/Q2UE40 ^@ Similarity ^@ Belongs to the PheA/TfdB FAD monooxygenase family. http://togogenome.org/gene/510516:AO090001000712 ^@ http://purl.uniprot.org/uniprot/Q2UML3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Common component of the spliceosome and rRNA processing machinery.|||nucleolus http://togogenome.org/gene/510516:AO090003000904 ^@ http://purl.uniprot.org/uniprot/Q2UK94 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ERG2 family.|||Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols.|||Endoplasmic reticulum membrane http://togogenome.org/gene/510516:AO090102000255 ^@ http://purl.uniprot.org/uniprot/Q2UAT1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090026000115 ^@ http://purl.uniprot.org/uniprot/Q2UFQ6 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/510516:AO090120000408 ^@ http://purl.uniprot.org/uniprot/Q2U626 ^@ Function|||Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.|||Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. http://togogenome.org/gene/510516:AO090038000139 ^@ http://purl.uniprot.org/uniprot/Q2U387 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) per subunit.|||Homotetramer. http://togogenome.org/gene/510516:AO090003000367 ^@ http://purl.uniprot.org/uniprot/Q2ULL2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/510516:AO090124000087 ^@ http://purl.uniprot.org/uniprot/Q2U730 ^@ Similarity ^@ Belongs to the HGH1 family. http://togogenome.org/gene/510516:AO090003001062 ^@ http://purl.uniprot.org/uniprot/Q2UJV1 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/510516:AO090003001067 ^@ http://purl.uniprot.org/uniprot/Q2UJU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FGGY kinase family.|||Cytoplasm http://togogenome.org/gene/510516:AO090102000476 ^@ http://purl.uniprot.org/uniprot/Q2UAA5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090120000100 ^@ http://purl.uniprot.org/uniprot/Q2U6T9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A22B family.|||Membrane http://togogenome.org/gene/510516:AO090020000489 ^@ http://purl.uniprot.org/uniprot/Q2U454 ^@ Similarity ^@ Belongs to the PET191 family. http://togogenome.org/gene/510516:AO090009000169 ^@ http://purl.uniprot.org/uniprot/Q2UUU8 ^@ Similarity ^@ Belongs to the MOG1 family. http://togogenome.org/gene/510516:AO090011000416 ^@ http://purl.uniprot.org/uniprot/Q2U0J5 ^@ Disruption Phenotype|||Function|||Subcellular Location Annotation ^@ Nucleus|||Reduces markedly the expression of hepA and abolishes the production of heptelidic acid.|||Transcription factor; part of the gene cluster that mediates the biosynthesis of heptelidic acid (HA), a sesquiterpene lactone that acts as an inhibitor of glyceraldehyde-3-phosphatedehydrogenase (GAPDH) and a growth inhibitor of the salt-tolerant lactic acid bacteria in soy sauce brewing (PubMed:30466366). Both hepR and hepS regulate the transcription of the heptelidic acid cluster, but they are not involved in mutual transcriptional regulation and act with different mechanisms (PubMed:30466366). http://togogenome.org/gene/510516:AO090023000641 ^@ http://purl.uniprot.org/uniprot/Q2UH03 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.|||GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.|||nucleolus http://togogenome.org/gene/510516:AO090009000050 ^@ http://purl.uniprot.org/uniprot/Q2UV46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ThrE exporter (TC 2.A.79) family.|||Membrane http://togogenome.org/gene/510516:AO090005000266 ^@ http://purl.uniprot.org/uniprot/Q2USW4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAN1 family.|||Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.|||Nucleus http://togogenome.org/gene/510516:AO090701000041 ^@ http://purl.uniprot.org/uniprot/Q2U9G3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aconitase/IPM isomerase family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.|||Mitochondrion http://togogenome.org/gene/510516:AO090026000760 ^@ http://purl.uniprot.org/uniprot/Q2UE51 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003000995 ^@ http://purl.uniprot.org/uniprot/Q2UK11 ^@ Function ^@ Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs. http://togogenome.org/gene/510516:AO090010000464 ^@ http://purl.uniprot.org/uniprot/Q2TWQ6 ^@ Similarity ^@ Belongs to the PAT1 family. http://togogenome.org/gene/510516:AO090012000065 ^@ http://purl.uniprot.org/uniprot/Q2UDR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090012000459 ^@ http://purl.uniprot.org/uniprot/Q2UCT1 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. http://togogenome.org/gene/510516:AO090010000015 ^@ http://purl.uniprot.org/uniprot/Q2TXT8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090003000196 ^@ http://purl.uniprot.org/uniprot/Q2UM03 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RAP1 family.|||Homodimer.|||Involved in the regulation of telomere length, clustering and has a specific role in telomere position effect (TPE).|||Nucleus|||telomere http://togogenome.org/gene/510516:AO090010000487 ^@ http://purl.uniprot.org/uniprot/Q2TWN5 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. HMG-CoA synthase family.|||Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA. http://togogenome.org/gene/510516:AO090012000941 ^@ http://purl.uniprot.org/uniprot/Q2UBM3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 7 (cellulase C) family.|||Secreted|||The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose. http://togogenome.org/gene/510516:AO090012000732 ^@ http://purl.uniprot.org/uniprot/Q2UC56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090003000309 ^@ http://purl.uniprot.org/uniprot/Q2ULQ7 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/510516:AO090012000328 ^@ http://purl.uniprot.org/uniprot/Q2UD41 ^@ Disruption Phenotype|||Function|||Induction|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.|||Cell membrane|||Does not significantly affect miconazole susceptibility.|||Expression is slightly up-regulated in the presence of miconazole.|||Pleiotropic ABC efflux transporter involved in the basal level of azole susceptibility. http://togogenome.org/gene/510516:AO090003000758 ^@ http://purl.uniprot.org/uniprot/Q9HFB3 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by C-terminal proteolytic cleavage by signaling protease (probably palB/RIM13) at neutral to alkaline ambient pH.|||Belongs to the pacC/RIM101 family.|||Binds to DNA. Interacts with palA, which binds to the two YPX[LI] motifs and is required for proteolytic processing (By similarity).|||Cytoplasm|||Nucleus|||Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid-expressed genes (By similarity). http://togogenome.org/gene/510516:AO090010000427 ^@ http://purl.uniprot.org/uniprot/Q2TWT6 ^@ Similarity ^@ Belongs to the class-A beta-lactamase family. http://togogenome.org/gene/510516:AO090026000008 ^@ http://purl.uniprot.org/uniprot/Q2UG07 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003001248 ^@ http://purl.uniprot.org/uniprot/Q2UJE7 ^@ Similarity ^@ Belongs to the indoleamine 2,3-dioxygenase family. http://togogenome.org/gene/510516:AO090701000140 ^@ http://purl.uniprot.org/uniprot/Q2U977 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELP5 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/510516:AO090038000162 ^@ http://purl.uniprot.org/uniprot/Q2U368 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090011000846 ^@ http://purl.uniprot.org/uniprot/Q2TZH9 ^@ Subcellular Location Annotation ^@ nuclear pore complex http://togogenome.org/gene/510516:AO090005001182 ^@ http://purl.uniprot.org/uniprot/Q2UQM6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the poly(A) polymerase family.|||Binds 2 magnesium ions. Also active with manganese.|||Nucleus|||Polymerase that creates the 3'-poly(A) tail of mRNA's. http://togogenome.org/gene/510516:AO090001000215 ^@ http://purl.uniprot.org/uniprot/Q2UNV7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090701000029 ^@ http://purl.uniprot.org/uniprot/Q2U9H5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat ELP2 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/510516:AO090012000808 ^@ http://purl.uniprot.org/uniprot/Q2UBZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the actin family.|||cytoskeleton http://togogenome.org/gene/510516:AO090009000070 ^@ http://purl.uniprot.org/uniprot/Q2UV29 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/510516:AO090011000468 ^@ http://purl.uniprot.org/uniprot/Q2U0E7 ^@ Similarity ^@ Belongs to the CWC22 family. http://togogenome.org/gene/510516:AO090003001386 ^@ http://purl.uniprot.org/uniprot/Q2UJ21 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090120000304 ^@ http://purl.uniprot.org/uniprot/Q2U6B7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/510516:AO090009000033 ^@ http://purl.uniprot.org/uniprot/Q2UV60 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/510516:AO090701000586 ^@ http://purl.uniprot.org/uniprot/Q2U836 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF8 family.|||Nucleus http://togogenome.org/gene/510516:AO090010000012 ^@ http://purl.uniprot.org/uniprot/Q2TXU1 ^@ Similarity ^@ Belongs to the proline racemase family. http://togogenome.org/gene/510516:AO090010000626 ^@ http://purl.uniprot.org/uniprot/Q2TWB7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090026000829 ^@ http://purl.uniprot.org/uniprot/Q2UDY8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PAN1 family.|||Cell membrane|||Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).|||Component of the PAN1 actin cytoskeleton-regulatory complex.|||Endosome membrane|||actin patch http://togogenome.org/gene/510516:AO090120000046 ^@ http://purl.uniprot.org/uniprot/Q2U6Y2 ^@ Similarity ^@ Belongs to the pyrroline-5-carboxylate reductase family. http://togogenome.org/gene/510516:AO090701000026 ^@ http://purl.uniprot.org/uniprot/Q2U9H8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Tom40 family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/510516:AO090026000084 ^@ http://purl.uniprot.org/uniprot/Q2UFT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EBP family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/510516:AO090023000070 ^@ http://purl.uniprot.org/uniprot/Q2UIF9 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/510516:AO090010000087 ^@ http://purl.uniprot.org/uniprot/Q2TXM4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 1 family.|||Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090003000009 ^@ http://purl.uniprot.org/uniprot/Q2UMG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/510516:AO090005001245 ^@ http://purl.uniprot.org/uniprot/Q2UQH4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGW family.|||Endoplasmic reticulum membrane|||Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. http://togogenome.org/gene/510516:AO090012000018 ^@ http://purl.uniprot.org/uniprot/Q2UDV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090102000126 ^@ http://purl.uniprot.org/uniprot/Q2UB36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.|||cytoskeleton http://togogenome.org/gene/510516:AO090010000771 ^@ http://purl.uniprot.org/uniprot/Q2TVY5 ^@ Function|||Similarity ^@ Belongs to the SEC10 family.|||Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. http://togogenome.org/gene/510516:AO090012000284 ^@ http://purl.uniprot.org/uniprot/Q2UD78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090038000309 ^@ http://purl.uniprot.org/uniprot/Q2U2V1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mago nashi family.|||Nucleus http://togogenome.org/gene/510516:AO090003000460 ^@ http://purl.uniprot.org/uniprot/Q2ULC8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090020000706 ^@ http://purl.uniprot.org/uniprot/Q2U3L6 ^@ Function|||Similarity ^@ Belongs to the peptidase S9A family.|||Belongs to the peptidase S9C family.|||This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser. http://togogenome.org/gene/510516:AO090005000845 ^@ http://purl.uniprot.org/uniprot/Q2URF8 ^@ Function|||Subcellular Location Annotation ^@ RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.|||nucleolus http://togogenome.org/gene/510516:AO090012000235 ^@ http://purl.uniprot.org/uniprot/Q2UDB8 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/510516:AO090701000473 ^@ http://purl.uniprot.org/uniprot/Q2U8D2 ^@ Function|||Similarity ^@ Belongs to the lysophospholipase family.|||Catalyzes the release of fatty acids from lysophospholipids. http://togogenome.org/gene/510516:AO090001000322 ^@ http://purl.uniprot.org/uniprot/Q2UNL0 ^@ Similarity|||Subunit ^@ Belongs to the transketolase family.|||Homodimer. http://togogenome.org/gene/510516:AO090011000220 ^@ http://purl.uniprot.org/uniprot/Q2U108 ^@ Similarity ^@ Belongs to the gamma-glutamylcyclotransferase family. http://togogenome.org/gene/510516:AO090011000550 ^@ http://purl.uniprot.org/uniprot/Q2U081 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Membrane http://togogenome.org/gene/510516:AO090009000166 ^@ http://purl.uniprot.org/uniprot/Q2UUV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HAUS1 family.|||spindle http://togogenome.org/gene/510516:AO090701000631 ^@ http://purl.uniprot.org/uniprot/Q2U7Z7 ^@ Similarity ^@ Belongs to the Cyclase 1 superfamily. http://togogenome.org/gene/510516:AO090012000801 ^@ http://purl.uniprot.org/uniprot/Q2UBZ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the universal ribosomal protein uS2 family.|||Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with rps21.|||Cytoplasm|||Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. http://togogenome.org/gene/510516:AO090011000807 ^@ http://purl.uniprot.org/uniprot/Q2TZL3 ^@ Similarity ^@ Belongs to the dihydrofolate reductase family. http://togogenome.org/gene/510516:AO090005000129 ^@ http://purl.uniprot.org/uniprot/Q2UT75 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRS1 family.|||Involved in ribosomal large subunit assembly.|||Nucleus http://togogenome.org/gene/510516:AO090020000383 ^@ http://purl.uniprot.org/uniprot/Q2U4D8 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. http://togogenome.org/gene/510516:AO090038000223 ^@ http://purl.uniprot.org/uniprot/Q2U325 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 3 family.|||Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090166000076 ^@ http://purl.uniprot.org/uniprot/Q2U9N8 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Homotetramer. http://togogenome.org/gene/510516:AO090005000750 ^@ http://purl.uniprot.org/uniprot/Q2URN8 ^@ Function|||Similarity ^@ Belongs to the type IB topoisomerase family.|||Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/510516:AO090701000739 ^@ http://purl.uniprot.org/uniprot/Q2U7Q9 ^@ Similarity ^@ Belongs to the glycosyltransferase 2 family. http://togogenome.org/gene/510516:AO090005000339 ^@ http://purl.uniprot.org/uniprot/Q2USQ2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090102000167 ^@ http://purl.uniprot.org/uniprot/Q2UAZ9 ^@ Disruption Phenotype|||Function ^@ 4'-hydroxy-3'-methoxypropiophenone carrier protein; part of the gene cluster that mediates the biosynthesis of 2,4'-dihydroxy-3'-methoxypropiophenone (PubMed:32885554). The first step of the pathway is the conversion of acetate into acetyl-CoA by the acyl-CoA ligase ppsA (PubMed:32885554). Acetyl-CoA is then used as a starter unit by the polyketide synthase ppsB and condensed with 4 malonyl-CoA unit to produce the pentaketide backbone (PubMed:32885554). During polyketide extension, the polykedite chain is probably reduced and dehydrated by the KR and PT domains, respectively (Probable). O-methylation seems to be catalyzed by an unknown methyltransferase rather than by the CMeT domain of ppsB (Probable). Two hydroxylations and one further decarboxylation step catalyzed by yet unknown enzymes are then required to yield 4'-hydroxy-3'-methoxypropiophenone (Probable). PpsC functions as a carrier protein to transport 4'-hydroxy-3'-methoxypropiophenone to a specific cell compartment in which 4'-hydroxy-3'-methoxypropiophenone is hydroxylated to 2,4'-dihydroxy-3'-methoxypropiophenone by a still to be identified enzyme (PubMed:32885554).|||Decreases the production of 2,4'-dihydroxy-3'-methoxypropiophenone and but leads to the accumulation of 4'-hydroxy-3'-methoxypropiophenone. http://togogenome.org/gene/510516:AO090020000209 ^@ http://purl.uniprot.org/uniprot/Q2U4T7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090012000494 ^@ http://purl.uniprot.org/uniprot/Q2UCQ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090102000360 ^@ http://purl.uniprot.org/uniprot/Q2UAJ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NMT1/THI5 family.|||Homodimer.|||Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway. Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP). The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. http://togogenome.org/gene/510516:AO090005000377 ^@ http://purl.uniprot.org/uniprot/Q2USL8 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. http://togogenome.org/gene/510516:AO090038000283 ^@ http://purl.uniprot.org/uniprot/Q2U2X3 ^@ Similarity ^@ Belongs to the RNR ribonuclease family. http://togogenome.org/gene/510516:AO090026000423 ^@ http://purl.uniprot.org/uniprot/Q2UEY9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/510516:AO090003000135 ^@ http://purl.uniprot.org/uniprot/Q2UM54 ^@ Similarity ^@ Belongs to the peptidase C2 family. PalB/RIM13 subfamily. http://togogenome.org/gene/510516:AO090010000546 ^@ http://purl.uniprot.org/uniprot/Q2TWI2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090003000301 ^@ http://purl.uniprot.org/uniprot/Q2ULR3 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/510516:AO090701000606 ^@ http://purl.uniprot.org/uniprot/Q2U818 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/510516:AO090011000293 ^@ http://purl.uniprot.org/uniprot/Q2U0V2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090020000375 ^@ http://purl.uniprot.org/uniprot/Q2U4E5 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/510516:AO090011000286 ^@ http://purl.uniprot.org/uniprot/Q2U0V9 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/510516:AO090023000633 ^@ http://purl.uniprot.org/uniprot/Q2UH11 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.|||Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. http://togogenome.org/gene/510516:AO090026000189 ^@ http://purl.uniprot.org/uniprot/Q76MU7 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Glutarylation at Lys-92 (H4K91glu) destabilizes nucleosomes by promoting dissociation of the H2A-H2B dimers from nucleosomes.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/510516:AO090113000138 ^@ http://purl.uniprot.org/uniprot/Q2U5H8 ^@ Biotechnology|||Disruption Phenotype|||Function|||Induction|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily.|||Cell membrane|||Expression is controlled by the kojic acid gene cluster transcription factor kojR (PubMed:21514215). Expression is also positively regulated by the secondary metabolism general regulator laeA (PubMed:21897021). Finally, nitrogen deficiency also positively regulates expression (PubMed:26657710).|||Kojic acid can be used for several biotechnological applications, including use as an antibiotic, as an additive to prevent browning of food materials, and as an antioxidant (PubMed:17119644). Kojic acid is also interesting as an inhibitor of tyrosinase (PubMed:7714722). Finally, kojic acid has also been shown to have strong nematicidal activity (PubMed:27197670).|||MFS-type transporter; part of the gene cluster that mediates the biosynthesis of 5-hydroxy-2-hydroxymethyl-1,4-pyrone, also know as kojic acid, a by-product in the fermentation process of malting rice that acts as a chelation agent (PubMed:20849972, PubMed:35034313). Involved in the seretion of kojic acid (PubMed:20849972).|||Reduces secretion of kojic acid. http://togogenome.org/gene/510516:AO090003000010 ^@ http://purl.uniprot.org/uniprot/Q2UMG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SVP26 family.|||Membrane http://togogenome.org/gene/510516:AO090038000110 ^@ http://purl.uniprot.org/uniprot/Q2U3B3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS17 family. http://togogenome.org/gene/510516:AO090005000704 ^@ http://purl.uniprot.org/uniprot/Q2URS8 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/510516:AO090005001583 ^@ http://purl.uniprot.org/uniprot/Q2UPM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the THOC5 family.|||Nucleus http://togogenome.org/gene/510516:AO090005000035 ^@ http://purl.uniprot.org/uniprot/Q2UTF9 ^@ Similarity ^@ Belongs to the pyrroline-5-carboxylate reductase family. http://togogenome.org/gene/510516:AO090138000051 ^@ http://purl.uniprot.org/uniprot/Q2U1Y1 ^@ Cofactor|||Similarity ^@ Belongs to the eukaryotic GSH synthase family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/510516:AO090026000731 ^@ http://purl.uniprot.org/uniprot/Q2UE78 ^@ Function|||Similarity ^@ Belongs to the tRNA-intron endonuclease family.|||Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. http://togogenome.org/gene/510516:AO090005001073 ^@ http://purl.uniprot.org/uniprot/Q2UQW6 ^@ Function|||Similarity ^@ Belongs to the VPS28 family.|||Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. http://togogenome.org/gene/510516:AO090672000006 ^@ http://purl.uniprot.org/uniprot/Q2UG16 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090005001278 ^@ http://purl.uniprot.org/uniprot/Q2UQE9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005001076 ^@ http://purl.uniprot.org/uniprot/Q2UQW3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.|||Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.|||Interacts with the U3 snoRNA and is associated with the 90S and 40S pre-ribosomes.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.|||nucleolus http://togogenome.org/gene/510516:AO090009000026 ^@ http://purl.uniprot.org/uniprot/Q2UV88 ^@ Similarity ^@ Belongs to the NmrA-type oxidoreductase family. http://togogenome.org/gene/510516:AO090003001104 ^@ http://purl.uniprot.org/uniprot/Q2UJR6 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/510516:AO090023000365 ^@ http://purl.uniprot.org/uniprot/Q2UHP3 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/510516:AO090103000016 ^@ http://purl.uniprot.org/uniprot/Q2TZ20 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LIMR family. LMBRD1 subfamily.|||Lysosome membrane|||Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors (By similarity). http://togogenome.org/gene/510516:AO090010000696 ^@ http://purl.uniprot.org/uniprot/Q2TW58 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. http://togogenome.org/gene/510516:AO090005001391 ^@ http://purl.uniprot.org/uniprot/Q2UQ49 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I NDUFA13 subunit family.|||Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090003000568 ^@ http://purl.uniprot.org/uniprot/Q2UL32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCM10 family.|||Nucleus http://togogenome.org/gene/510516:AO090005000617 ^@ http://purl.uniprot.org/uniprot/Q2US06 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/510516:AO090010000458 ^@ http://purl.uniprot.org/uniprot/Q2TWR2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090010000564 ^@ http://purl.uniprot.org/uniprot/Q2TWG7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005001504 ^@ http://purl.uniprot.org/uniprot/Q2UPU5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SSU72 phosphatase family.|||Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Ssu72 is required for 3'-end formation of snoRNAs (By similarity).|||Component of the cleavage and polyadenylation factor (CPF) complex.|||Nucleus|||Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (rpb1). http://togogenome.org/gene/510516:AO090701000830 ^@ http://purl.uniprot.org/uniprot/Q2U7I1 ^@ Function ^@ Delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides. Required for the formation of the di-unsaturated sphingoid base (E,E)-sphinga-4,8-dienine during glucosylceramide (GluCer) biosynthesis. http://togogenome.org/gene/510516:AO090103000222 ^@ http://purl.uniprot.org/uniprot/Q2TYJ2 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/510516:AO090010000641 ^@ http://purl.uniprot.org/uniprot/Q2TWA3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane|||Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. http://togogenome.org/gene/510516:AO090001000740 ^@ http://purl.uniprot.org/uniprot/Q2UMI6 ^@ Function|||Similarity ^@ Belongs to the HisA/HisF family.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain.|||In the C-terminal section; belongs to the HisA/HisF family. http://togogenome.org/gene/510516:AO090138000093 ^@ http://purl.uniprot.org/uniprot/Q2U1U5 ^@ Similarity ^@ Belongs to the amino acid/polyamine transporter 2 family. http://togogenome.org/gene/510516:AO090124000066 ^@ http://purl.uniprot.org/uniprot/Q2U750 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003000209 ^@ http://purl.uniprot.org/uniprot/Q2ULZ4 ^@ Similarity ^@ Belongs to the TTC36 family. http://togogenome.org/gene/510516:AO090701000244 ^@ http://purl.uniprot.org/uniprot/Q2U8Y5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 3 family.|||Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090003000663 ^@ http://purl.uniprot.org/uniprot/Q2UKV2 ^@ Similarity ^@ Belongs to the COG3 family. http://togogenome.org/gene/510516:AO090005000194 ^@ http://purl.uniprot.org/uniprot/Q2UT24 ^@ Similarity ^@ Belongs to the four-carbon acid sugar kinase family. http://togogenome.org/gene/510516:AO090023000912 ^@ http://purl.uniprot.org/uniprot/Q2UGA8 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/510516:AO090011000479 ^@ http://purl.uniprot.org/uniprot/Q2U0D9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.|||Belongs to the CNOT2/3/5 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/510516:AO090011000110 ^@ http://purl.uniprot.org/uniprot/Q2U1A2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090103000007 ^@ http://purl.uniprot.org/uniprot/Q2TZ28 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/510516:AO090038000232 ^@ http://purl.uniprot.org/uniprot/Q2U316 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. FKBP1 subfamily.|||Cytoplasm|||Inhibited by both FK506 and rapamycin.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). http://togogenome.org/gene/510516:AO090701000430 ^@ http://purl.uniprot.org/uniprot/Q2U8H4 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. http://togogenome.org/gene/510516:AO090011000345 ^@ http://purl.uniprot.org/uniprot/Q2U0Q4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 27 family.|||Nucleus http://togogenome.org/gene/510516:AO090009000295 ^@ http://purl.uniprot.org/uniprot/Q2UUJ1 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/510516:AO090001000492 ^@ http://purl.uniprot.org/uniprot/Q2UN61 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 53 family.|||Endogalactanase involved in the degradation of plant cell wall polysaccharides, and more particularly of hairy regions of pectin.|||Secreted http://togogenome.org/gene/510516:AO090005000456 ^@ http://purl.uniprot.org/uniprot/Q2USE6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Expected to bind 2 Fe(2+) ions per subunit.|||Membrane|||Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. http://togogenome.org/gene/510516:AO090011000781 ^@ http://purl.uniprot.org/uniprot/Q2TZN9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.|||Cytoplasm|||Nucleus http://togogenome.org/gene/510516:AO090010000721 ^@ http://purl.uniprot.org/uniprot/Q2TW35 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/510516:AO090009000091 ^@ http://purl.uniprot.org/uniprot/Q2UV14 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/510516:AO090003001164 ^@ http://purl.uniprot.org/uniprot/Q2UJL4 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/510516:AO090001000329 ^@ http://purl.uniprot.org/uniprot/Q2UNK3 ^@ Similarity ^@ Belongs to the GDA1/CD39 NTPase family. http://togogenome.org/gene/510516:AO090010000617 ^@ http://purl.uniprot.org/uniprot/Q2TWC6 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. http://togogenome.org/gene/510516:AO090005001132 ^@ http://purl.uniprot.org/uniprot/Q2UQR7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS8 family. http://togogenome.org/gene/510516:AO090003001401 ^@ http://purl.uniprot.org/uniprot/Q2UJ09 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090102000191 ^@ http://purl.uniprot.org/uniprot/Q2UAX8 ^@ Similarity ^@ Belongs to the Cyclase 1 superfamily. http://togogenome.org/gene/510516:AO090038000585 ^@ http://purl.uniprot.org/uniprot/Q2U264 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPA43 RNA polymerase subunit family.|||nucleolus http://togogenome.org/gene/510516:AO090012000485 ^@ http://purl.uniprot.org/uniprot/Q2UCR0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II.|||Belongs to the helicase family. RAD3/XPD subfamily.|||Nucleus http://togogenome.org/gene/510516:AO090020000106 ^@ http://purl.uniprot.org/uniprot/Q2U525 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090003001251 ^@ http://purl.uniprot.org/uniprot/Q2UJE4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SYF2 family.|||Involved in pre-mRNA splicing.|||May be part of a spliceosome complex.|||Nucleus http://togogenome.org/gene/510516:AO090038000097 ^@ http://purl.uniprot.org/uniprot/Q2U3C5 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090005000274 ^@ http://purl.uniprot.org/uniprot/Q2USV9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090120000249 ^@ http://purl.uniprot.org/uniprot/Q2U6G2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL14 family. http://togogenome.org/gene/510516:AO090005001531 ^@ http://purl.uniprot.org/uniprot/Q2UPS2 ^@ Similarity ^@ In the N-terminal section; belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/510516:AO090003000298 ^@ http://purl.uniprot.org/uniprot/Q2ULR6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CENP-K/MCM22 family.|||Nucleus|||centromere http://togogenome.org/gene/510516:AO090113000137 ^@ http://purl.uniprot.org/uniprot/Q2U5H9 ^@ Biotechnology|||Disruption Phenotype|||Function|||Induction|||Subcellular Location Annotation ^@ Expression is positively regulated by the secondary metabolism general regulator laeA (PubMed:21897021). Expression is negatively regulated by the transcription factor kpeA (PubMed:30790620).|||Impairs the transcription of kojA and kojT, and blocks the production of kojic acid.|||Kojic acid can be used for several biotechnological applications, including use as an antibiotic, as an additive to prevent browning of food materials, and as an antioxidant (PubMed:17119644). Kojic acid is also interesting as an inhibitor of tyrosinase (PubMed:7714722). Finally, kojic acid has also been shown to have strong nematicidal activity (PubMed:27197670).|||Nucleus|||Transcription factor that regulates the gene cluster that mediates the biosynthesis of 5-hydroxy-2-hydroxymethyl-1,4-pyrone, also know as kojic acid, a by-product in the fermentation process of malting rice that acts as a chelation agent. http://togogenome.org/gene/510516:AO090001000497 ^@ http://purl.uniprot.org/uniprot/Q2UN57 ^@ Function|||Similarity ^@ Belongs to the UBR1 family.|||Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. http://togogenome.org/gene/510516:AO090120000095 ^@ http://purl.uniprot.org/uniprot/Q2U6U3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090011000910 ^@ http://purl.uniprot.org/uniprot/Q2TZC6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.|||This enzyme is required for electron transfer from NADP to cytochrome P450. http://togogenome.org/gene/510516:AO090023000402 ^@ http://purl.uniprot.org/uniprot/Q2UHL3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000789 ^@ http://purl.uniprot.org/uniprot/Q2URK6 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/510516:AO090020000116 ^@ http://purl.uniprot.org/uniprot/Q2U516 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF1 family.|||Mitochondrion inner membrane|||Probably involved in the biogenesis of the COX complex. http://togogenome.org/gene/510516:AO090011000004 ^@ http://purl.uniprot.org/uniprot/Q2U1J7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090102000629 ^@ http://purl.uniprot.org/uniprot/Q2U9X3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090020000009 ^@ http://purl.uniprot.org/uniprot/Q2U5A6 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/510516:AO090010000441 ^@ http://purl.uniprot.org/uniprot/Q2TWS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CSC1 (TC 1.A.17) family.|||Membrane http://togogenome.org/gene/510516:AO090003000631 ^@ http://purl.uniprot.org/uniprot/Q2UKX6 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/510516:AO090120000208 ^@ http://purl.uniprot.org/uniprot/Q2U6J6 ^@ Similarity ^@ Belongs to the glycosyltransferase 32 family. http://togogenome.org/gene/510516:AO090005001611 ^@ http://purl.uniprot.org/uniprot/Q2UPK0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat BOP1/ERB1 family.|||Component of the NOP7 complex, composed of erb1, nop7 and ytm1. The complex is held together by erb1, which interacts with nop7 via its N-terminal domain and with ytm1 via a high-affinity interaction between the seven-bladed beta-propeller domains of the 2 proteins. The NOP7 complex associates with the 66S pre-ribosome.|||Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.|||nucleolus|||nucleoplasm http://togogenome.org/gene/510516:AO090005001450 ^@ http://purl.uniprot.org/uniprot/Q2UPZ4 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/510516:AO090023000227 ^@ http://purl.uniprot.org/uniprot/Q2UI16 ^@ Similarity ^@ Belongs to the ZPR1 family. http://togogenome.org/gene/510516:AO090120000214 ^@ http://purl.uniprot.org/uniprot/Q2U6J2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.|||Membrane http://togogenome.org/gene/510516:AO090023000724 ^@ http://purl.uniprot.org/uniprot/Q2UGT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MPDU1 (TC 2.A.43.3) family.|||Membrane http://togogenome.org/gene/510516:AO090005000738 ^@ http://purl.uniprot.org/uniprot/Q2URP7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DIM1 family.|||Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis.|||Nucleus http://togogenome.org/gene/510516:AO090005000611 ^@ http://purl.uniprot.org/uniprot/Q2US12 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MET18/MMS19 family.|||Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.|||Nucleus http://togogenome.org/gene/510516:AO090011000025 ^@ http://purl.uniprot.org/uniprot/Q2U1H7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090012000495 ^@ http://purl.uniprot.org/uniprot/Q2UCQ0 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetylation of histone H3 leads to transcriptional activation. H3K14ac formation by gcn5 is promoted by H3S10ph. H3K14ac can also be formed by esa1. H3K56ac formation occurs predominantly in newly synthesized H3 molecules during G1, S and G2/M of the cell cycle and may be involved in DNA repair (By similarity).|||Belongs to the histone H3 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Mono-, di- and trimethylated by the COMPASS complex to form H3K4me1/2/3. H3K4me activates gene expression by regulating transcription elongation and plays a role in telomere length maintenance. H3K4me enrichment correlates with transcription levels, and occurs in a 5' to 3' gradient with H3K4me3 enrichment at the 5'-end of genes, shifting to H3K4me2 and then H3K4me1. Methylated by set2 to form H3K36me. H3K36me represses gene expression. Methylated by dot1 to form H3K79me. H3K79me is required for association of SIR proteins with telomeric regions and for telomeric silencing. The COMPASS-mediated formation of H3K4me2/3 and the dot1-mediated formation of H3K79me require H2BK123ub1 (By similarity).|||Nucleus|||Phosphorylated to form H3S10ph. H3S10ph promotes subsequent H3K14ac formation and is required for transcriptional activation through TBP recruitment to the promoters (By similarity).|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.|||To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H3K4me1/2/3 = mono-, di- and trimethylated Lys-5; H3K9ac = acetylated Lys-10; H3K9me1 = monomethylated Lys-10; H3S10ph = phosphorylated Ser-11; H3K14ac = acetylated Lys-15; H3K14me2 = dimethylated Lys-15; H3K18ac = acetylated Lys-19; H3K18me1 = monomethylated Lys-19; H3K23ac = acetylated Lys-24; H3K23me1 = monomethylated Lys-24; H3K27ac = acetylated Lys-28; H3K27me1/2/3 = mono-, di- and trimethylated Lys-28; H3K36ac = acetylated Lys-37; H3K36me1/2/3 = mono-, di- and trimethylated Lys-37; H3K56ac = acetylated Lys-57; H3K64ac = acetylated Lys-65; H3K79me1/2/3 = mono-, di- and trimethylated Lys-80. http://togogenome.org/gene/510516:AO090012000436 ^@ http://purl.uniprot.org/uniprot/Q2UCV1 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/510516:AO090138000119 ^@ http://purl.uniprot.org/uniprot/Q2U1S1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 4 family.|||Secreted http://togogenome.org/gene/510516:AO090012000400 ^@ http://purl.uniprot.org/uniprot/Q2UCY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF7 family.|||Nucleus http://togogenome.org/gene/510516:AO090011000651 ^@ http://purl.uniprot.org/uniprot/Q2TZZ9 ^@ Similarity ^@ In the C-terminal section; belongs to the DHPS family. http://togogenome.org/gene/510516:AO090113000064 ^@ http://purl.uniprot.org/uniprot/Q2U5P0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oligopeptide OPT transporter family.|||Membrane http://togogenome.org/gene/510516:AO090701000678 ^@ http://purl.uniprot.org/uniprot/Q2U7W2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associated with the spliceosome.|||Belongs to the CWC24 family.|||Involved in pre-mRNA splicing.|||Nucleus http://togogenome.org/gene/510516:AO090701000658 ^@ http://purl.uniprot.org/uniprot/Q2U7X8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090011000486 ^@ http://purl.uniprot.org/uniprot/Q2U0D3 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/510516:AO090023000501 ^@ http://purl.uniprot.org/uniprot/Q2UHC4 ^@ Subcellular Location Annotation ^@ Membrane|||Vacuole membrane http://togogenome.org/gene/510516:AO090003001140 ^@ http://purl.uniprot.org/uniprot/Q2UJN4 ^@ Similarity ^@ Belongs to the glycosyltransferase 34 family. http://togogenome.org/gene/510516:AO090005001027 ^@ http://purl.uniprot.org/uniprot/Q2UR04 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003000887 ^@ http://purl.uniprot.org/uniprot/Q2UKA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FRG1 family.|||nucleolus http://togogenome.org/gene/510516:AO090003001407 ^@ http://purl.uniprot.org/uniprot/Q2UJ04 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/510516:AO090023000543 ^@ http://purl.uniprot.org/uniprot/Q2UH87 ^@ Similarity ^@ Belongs to the flavin-dependent halogenase family. http://togogenome.org/gene/510516:AO090023000977 ^@ http://purl.uniprot.org/uniprot/Q2UG50 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/510516:AO090005001299 ^@ http://purl.uniprot.org/uniprot/Q2UQD1 ^@ Similarity ^@ Belongs to the prefoldin subunit beta family. http://togogenome.org/gene/510516:AO090103000036 ^@ http://purl.uniprot.org/uniprot/Q2TZ03 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/510516:AO090012000209 ^@ http://purl.uniprot.org/uniprot/Q2UDE1 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/510516:AO090102000349 ^@ http://purl.uniprot.org/uniprot/Q2UAK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Endomembrane system|||Vacuole membrane http://togogenome.org/gene/510516:AO090102000616 ^@ http://purl.uniprot.org/uniprot/Q2U9Y5 ^@ Subcellular Location Annotation ^@ Nucleus|||kinetochore http://togogenome.org/gene/510516:AO090023000752 ^@ http://purl.uniprot.org/uniprot/Q2UGQ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pescadillo family.|||Component of the NOP7 complex, composed of erb1, nop7 and ytm1. The complex is held together by erb1, which interacts with nop7 via its N-terminal domain and with ytm1 via a high-affinity interaction between the seven-bladed beta-propeller domains of the 2 proteins. The NOP7 complex associates with the 66S pre-ribosome.|||Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.|||nucleolus|||nucleoplasm http://togogenome.org/gene/510516:AO090701000228 ^@ http://purl.uniprot.org/uniprot/Q2U900 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPC7 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/510516:AO090113000158 ^@ http://purl.uniprot.org/uniprot/Q2U5F9 ^@ Similarity ^@ Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family. http://togogenome.org/gene/510516:AO090038000395 ^@ http://purl.uniprot.org/uniprot/P41756 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/510516:AO090701000885 ^@ http://purl.uniprot.org/uniprot/Q2U7D2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Alpha-L-arabinofuranosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Releases L-arabinose from arabinoxylan (By similarity).|||Belongs to the glycosyl hydrolase 62 family.|||Secreted http://togogenome.org/gene/510516:AO090003001001 ^@ http://purl.uniprot.org/uniprot/Q2UK05 ^@ Similarity ^@ Belongs to the VPS26 family. http://togogenome.org/gene/510516:AO090001000614 ^@ http://purl.uniprot.org/uniprot/Q2UMV1 ^@ Similarity ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family. http://togogenome.org/gene/510516:AO090023000474 ^@ http://purl.uniprot.org/uniprot/Q2UHE9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 72 family.|||Cell membrane|||Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in cell wall morphogenesis. http://togogenome.org/gene/510516:AO090003001099 ^@ http://purl.uniprot.org/uniprot/Q2UJS1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the xanthine dehydrogenase family.|||Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.|||Binds 2 [2Fe-2S] clusters.|||Peroxisome http://togogenome.org/gene/510516:AO090001000586 ^@ http://purl.uniprot.org/uniprot/Q2UMX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090026000121 ^@ http://purl.uniprot.org/uniprot/Q2UFQ0 ^@ Similarity ^@ Belongs to the PheA/TfdB FAD monooxygenase family. http://togogenome.org/gene/510516:AO090020000238 ^@ http://purl.uniprot.org/uniprot/Q2U4R0 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090023000830 ^@ http://purl.uniprot.org/uniprot/Q2UGI4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL36 family. http://togogenome.org/gene/510516:AO090005001174 ^@ http://purl.uniprot.org/uniprot/Q2UQN3 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/510516:AO090009000260 ^@ http://purl.uniprot.org/uniprot/Q2UUM2 ^@ Disruption Phenotype|||Function|||Induction|||Similarity ^@ Belongs to the wetA family.|||BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (PubMed:19850144). They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity).|||Expression is controlled by abaA (PubMed:19850144).|||Loses conidial pigments and exhibits autolytic phenotype (PubMed:19850144). http://togogenome.org/gene/510516:AO090003001195 ^@ http://purl.uniprot.org/uniprot/Q2UJI8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the very long-chain fatty acids dehydratase HACD family.|||Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/510516:AO090010000774 ^@ http://purl.uniprot.org/uniprot/Q2TVY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the rad17/RAD24 family.|||Nucleus http://togogenome.org/gene/510516:AO090701000126 ^@ http://purl.uniprot.org/uniprot/Q2U991 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/510516:AO090102000043 ^@ http://purl.uniprot.org/uniprot/Q2UBA9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090124000037 ^@ http://purl.uniprot.org/uniprot/Q2U777 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.|||Membrane http://togogenome.org/gene/510516:AO090026000013 ^@ http://purl.uniprot.org/uniprot/Q2UG02 ^@ Similarity|||Subunit ^@ Belongs to the fungal fatty acid synthetase subunit beta family.|||[Alpha(6)beta(6)] hexamers of two multifunctional subunits (alpha and beta). http://togogenome.org/gene/510516:AO090003000665 ^@ http://purl.uniprot.org/uniprot/Q2UKV0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP9 family.|||RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity).|||nucleolus http://togogenome.org/gene/510516:AO090023000861 ^@ http://purl.uniprot.org/uniprot/Q2UGF5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ELP1/IKA1 family.|||Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.|||Cytoplasm|||Nucleus http://togogenome.org/gene/510516:AO090011000289 ^@ http://purl.uniprot.org/uniprot/Q2U0V6 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.|||Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of lanosterol to form eburicol. http://togogenome.org/gene/510516:AO090010000155 ^@ http://purl.uniprot.org/uniprot/Q2TXG4 ^@ Function|||Similarity ^@ 2-methylcitrate dehydratase-like protein; part of the gene cluster that mediates the biosynthesis of oryzines, natural products with an unusual maleidride backbone (PubMed:30104550). The two subunits of the fungal fatty acid synthase oryfasA and oryfasB probably form octenoic acid (Probable). This fatty acid is most likely activated by the acyl-CoA ligase oryP to give octenyl-CoA before the citrate synthase-like protein oryE catalyzes condensation with oxaloacetate to form tricarboxylic acid (Probable). The next steps of the pathways are conjectural, but a favorite possible route has been proposed, beginning with decarboxylation and concomitant dehydration by the decarboxylase oryM, followed by tautomerization, which may lead to the production of a diene intermediate (Probable). Reduction of this diene intermediate could give the known metabolite piliformic acid (Probable). On the pathway to oryzine B and oryzine A, however, hydroxylation of the diene by the alpha-ketoglutarate-dependent dioxygenase oryG and lactonisation by the lactonohydrolases oryH or oryL could give oryzine B directly (Probable). Finally, enoyl reduction by the dehydrogenase oryD would then convert oryzine B into oryzine A (Probable).|||Belongs to the PrpD family. http://togogenome.org/gene/510516:AO090012000413 ^@ http://purl.uniprot.org/uniprot/Q2UCX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/510516:AO090120000290 ^@ http://purl.uniprot.org/uniprot/Q2U6C9 ^@ Function|||Similarity ^@ Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.|||Belongs to the proteasome subunit S2 family. http://togogenome.org/gene/510516:AO090001000722 ^@ http://purl.uniprot.org/uniprot/Q2UMK3 ^@ Similarity|||Subunit ^@ Associated with the spliceosome.|||Belongs to the crooked-neck family. http://togogenome.org/gene/510516:AO090003001008 ^@ http://purl.uniprot.org/uniprot/Q2UJZ9 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/510516:AO090012000996 ^@ http://purl.uniprot.org/uniprot/Q2UBH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/510516:AO090120000186 ^@ http://purl.uniprot.org/uniprot/Q2U6L7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FMP46 family.|||Mitochondrion|||Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules. http://togogenome.org/gene/510516:AO090701000693 ^@ http://purl.uniprot.org/uniprot/Q2U7U9 ^@ Similarity ^@ Belongs to the DCP1 family. http://togogenome.org/gene/510516:AO090026000080 ^@ http://purl.uniprot.org/uniprot/Q2UFT8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/510516:AO090020000539 ^@ http://purl.uniprot.org/uniprot/Q2U409 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SYG1 (TC 2.A.94) family.|||Membrane http://togogenome.org/gene/510516:AO090011000855 ^@ http://purl.uniprot.org/uniprot/Q2TZH0 ^@ Similarity ^@ Belongs to the tRNA pseudouridine synthase TruA family. http://togogenome.org/gene/510516:AO090701000062 ^@ http://purl.uniprot.org/uniprot/Q2U9E3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0220 family.|||Membrane http://togogenome.org/gene/510516:AO090003000315 ^@ http://purl.uniprot.org/uniprot/Q2ULQ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP core protein family.|||Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.|||Component of the heptameric LSM1-LSM7 complex, which consists of LSM1, LSM2, LSM3, LSM4, LSM5, LSM6 and LSM7. Component of the heptameric LSM2-LSM8 complex, which consists of LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8. The LSm subunits form a seven-membered ring structure with a doughnut shape.|||Nucleus|||Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. http://togogenome.org/gene/510516:AO090011000774 ^@ http://purl.uniprot.org/uniprot/Q2TZP5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/510516:AO090001000075 ^@ http://purl.uniprot.org/uniprot/P24021 ^@ Activity Regulation|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the nuclease type I family.|||Binds 3 divalent metal cations.|||Hydrolyzes only single-stranded DNA and RNA without apparent specificity for bases.|||Inhibited by inorganic phosphate (Pi).|||Monomer. http://togogenome.org/gene/510516:AO090701000897 ^@ http://purl.uniprot.org/uniprot/Q2U7C1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005001567 ^@ http://purl.uniprot.org/uniprot/Q2UPP1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aromatic-ring hydroxylase family. KMO subfamily.|||Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.|||Mitochondrion outer membrane http://togogenome.org/gene/510516:AO090120000099 ^@ http://purl.uniprot.org/uniprot/Q2U6U0 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family. PPIL1 subfamily.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). http://togogenome.org/gene/510516:AO090023000807 ^@ http://purl.uniprot.org/uniprot/Q2UGK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the INSIG family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/510516:AO090023000324 ^@ http://purl.uniprot.org/uniprot/Q2UHT0 ^@ Similarity ^@ Belongs to the nuclease type I family. http://togogenome.org/gene/510516:AO090003000777 ^@ http://purl.uniprot.org/uniprot/Q2UKJ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090120000068 ^@ http://purl.uniprot.org/uniprot/Q877A8 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the catalase family.|||By hydrogen peroxide.|||Homotetramer.|||Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide through its degradation into water and oxygen.|||Secreted http://togogenome.org/gene/510516:AO090011000703 ^@ http://purl.uniprot.org/uniprot/Q2TZV6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090009000281 ^@ http://purl.uniprot.org/uniprot/Q2UUK4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. http://togogenome.org/gene/510516:AO090103000023 ^@ http://purl.uniprot.org/uniprot/Q2TZ13 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/510516:AO090026000393 ^@ http://purl.uniprot.org/uniprot/Q2UF12 ^@ Similarity ^@ Belongs to the SDHAF4 family. http://togogenome.org/gene/510516:AO090020000689 ^@ http://purl.uniprot.org/uniprot/Q2U3N3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090701000685 ^@ http://purl.uniprot.org/uniprot/Q2U7V6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the squalene monooxygenase family.|||Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.|||Endoplasmic reticulum membrane|||Microsome membrane http://togogenome.org/gene/510516:AO090005001238 ^@ http://purl.uniprot.org/uniprot/Q2UQI1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090102000488 ^@ http://purl.uniprot.org/uniprot/Q2UA94 ^@ Similarity ^@ Belongs to the nucleosome assembly protein (NAP) family. http://togogenome.org/gene/510516:AO090009000402 ^@ http://purl.uniprot.org/uniprot/Q2UU96 ^@ Similarity ^@ Belongs to the KRI1 family. http://togogenome.org/gene/510516:AO090011000938 ^@ http://purl.uniprot.org/uniprot/Q2TZA1 ^@ Similarity ^@ Belongs to the TIP41 family. http://togogenome.org/gene/510516:AO090038000279 ^@ http://purl.uniprot.org/uniprot/Q2U2X7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 17 family.|||Cell membrane|||Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation and also function biosynthetically as a transglycosylase.|||Membrane|||cell wall http://togogenome.org/gene/510516:AO090001000064 ^@ http://purl.uniprot.org/uniprot/Q2UP91 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/510516:AO090138000049 ^@ http://purl.uniprot.org/uniprot/Q2U1Y3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the hydrogen channel family.|||Homodimer.|||Membrane http://togogenome.org/gene/510516:AO090005000092 ^@ http://purl.uniprot.org/uniprot/Q2UTA9 ^@ Similarity ^@ Belongs to the rtf2 family. http://togogenome.org/gene/510516:AO090026000441 ^@ http://purl.uniprot.org/uniprot/Q2UEX3 ^@ Function|||Subcellular Location Annotation ^@ May act as a zinc-influx transporter.|||Membrane http://togogenome.org/gene/510516:AO090003000045 ^@ http://purl.uniprot.org/uniprot/Q2UMD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RBT5 family.|||Cell membrane|||Membrane|||cell wall http://togogenome.org/gene/510516:AO090009000312 ^@ http://purl.uniprot.org/uniprot/Q2UUH5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aldolase class II family. MtnB subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).|||Cytoplasm http://togogenome.org/gene/510516:AO090012000711 ^@ http://purl.uniprot.org/uniprot/Q2UC74 ^@ Similarity ^@ Belongs to the XFP family. http://togogenome.org/gene/510516:AO090023000240 ^@ http://purl.uniprot.org/uniprot/Q2UI03 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the VPS11 family.|||Component of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex. Component of the class C core vacuole/endosome tethering (CORVET) complex.|||Vacuole membrane http://togogenome.org/gene/510516:AO090120000382 ^@ http://purl.uniprot.org/uniprot/Q2U648 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/510516:AO090009000447 ^@ http://purl.uniprot.org/uniprot/Q2UU58 ^@ Similarity ^@ Belongs to the CNOT9 family. http://togogenome.org/gene/510516:AO090009000648 ^@ http://purl.uniprot.org/uniprot/Q2UTP5 ^@ Similarity ^@ Belongs to the ubiquitin-activating E1 family. http://togogenome.org/gene/510516:AO090003000905 ^@ http://purl.uniprot.org/uniprot/Q2UK93 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 12 (cellulase H) family.|||Catalyzes endohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan with retention of the beta-configuration of the glycosyl residues. Specific for xyloglucan and does not hydrolyze other cell wall components (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090012000890 ^@ http://purl.uniprot.org/uniprot/Q2UBS1 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/510516:AO090701000842 ^@ http://purl.uniprot.org/uniprot/Q2U7H0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.|||Membrane http://togogenome.org/gene/510516:AO090120000165 ^@ http://purl.uniprot.org/uniprot/Q2U6N5 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/510516:AO090012000376 ^@ http://purl.uniprot.org/uniprot/Q2UD00 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000539 ^@ http://purl.uniprot.org/uniprot/Q2US75 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/510516:AO090010000204 ^@ http://purl.uniprot.org/uniprot/Q2TXC1 ^@ Function|||Similarity ^@ Belongs to the phytoene/squalene synthase family.|||Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene. http://togogenome.org/gene/510516:AO090011000145 ^@ http://purl.uniprot.org/uniprot/Q2U171 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090102000644 ^@ http://purl.uniprot.org/uniprot/Q2U9W1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090026000347 ^@ http://purl.uniprot.org/uniprot/Q2UF50 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SNAP family.|||Membrane|||Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. http://togogenome.org/gene/510516:AO090023000644 ^@ http://purl.uniprot.org/uniprot/Q2UH00 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).|||Belongs to the DEAD box helicase family. DDX23/PRP28 subfamily.|||Component of the U5 snRNP complex.|||Cytoplasm|||Nucleus|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. http://togogenome.org/gene/510516:AO090102000190 ^@ http://purl.uniprot.org/uniprot/Q2UAX9 ^@ Function|||Similarity ^@ Belongs to the cyanase family.|||Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. http://togogenome.org/gene/510516:AO090102000630 ^@ http://purl.uniprot.org/uniprot/Q2U9X2 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/510516:AO090010000026 ^@ http://purl.uniprot.org/uniprot/Q2TXS8 ^@ Similarity ^@ Belongs to the PhyH family. http://togogenome.org/gene/510516:AO090023000491 ^@ http://purl.uniprot.org/uniprot/Q2UHD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090005000780 ^@ http://purl.uniprot.org/uniprot/Q2URL5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dUTPase family.|||Homotrimer.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/510516:AO090026000553 ^@ http://purl.uniprot.org/uniprot/Q2UEN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family. SMC2 subfamily.|||Nucleus http://togogenome.org/gene/510516:AO090003000140 ^@ http://purl.uniprot.org/uniprot/Q2UM50 ^@ Function|||Similarity ^@ Belongs to the glyoxalase I family.|||Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. http://togogenome.org/gene/510516:AO090023000219 ^@ http://purl.uniprot.org/uniprot/Q2UI24 ^@ Similarity ^@ Belongs to the SEN54 family. http://togogenome.org/gene/510516:AO090102000516 ^@ http://purl.uniprot.org/uniprot/Q2UA71 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.|||Component of the HAT-B complex composed of at least hat1 and hat2. The HAT-B complex binds to histone H4 tail.|||Cytoplasm|||Nucleus|||Regulatory subunit of the histone acetylase B (HAT-B) complex. The complex acetylates 'Lys-12' of histone H4 which is required for telomeric silencing. http://togogenome.org/gene/510516:AO090003001338 ^@ http://purl.uniprot.org/uniprot/Q2UJ67 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ARPC3 family.|||Component of the Arp2/3 complex.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.|||cytoskeleton http://togogenome.org/gene/510516:AO090012000869 ^@ http://purl.uniprot.org/uniprot/Q2UBT8 ^@ Function ^@ Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway. http://togogenome.org/gene/510516:AO090138000081 ^@ http://purl.uniprot.org/uniprot/Q2U1V6 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. http://togogenome.org/gene/510516:AO090003000064 ^@ http://purl.uniprot.org/uniprot/Q2UMB6 ^@ Similarity ^@ Belongs to the RUS1 family. http://togogenome.org/gene/510516:AO090010000529 ^@ http://purl.uniprot.org/uniprot/Q2TWJ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/510516:AO090010000733 ^@ http://purl.uniprot.org/uniprot/Q2TW23 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003000741 ^@ http://purl.uniprot.org/uniprot/Q2UKN1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/510516:AO090012000796 ^@ http://purl.uniprot.org/uniprot/Q2UC04 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP5/NOP56 family.|||Required for pre-18S rRNA processing. May bind microtubules (By similarity).|||nucleolus http://togogenome.org/gene/510516:AO090026000613 ^@ http://purl.uniprot.org/uniprot/Q2UEH8 ^@ Similarity ^@ In the C-terminal section; belongs to the peptidase M41 family.|||In the N-terminal section; belongs to the AAA ATPase family. http://togogenome.org/gene/510516:AO090026000364 ^@ http://purl.uniprot.org/uniprot/Q2UF37 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/510516:AO090009000006 ^@ http://purl.uniprot.org/uniprot/Q2UV82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.|||Membrane http://togogenome.org/gene/510516:AO090005001196 ^@ http://purl.uniprot.org/uniprot/Q2UQL5 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/510516:AO090701000640 ^@ http://purl.uniprot.org/uniprot/Q2U7Z1 ^@ Similarity ^@ Belongs to the HMG-CoA reductase family. http://togogenome.org/gene/510516:AO090001000404 ^@ http://purl.uniprot.org/uniprot/Q2UND9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003000470 ^@ http://purl.uniprot.org/uniprot/Q2ULB8 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. http://togogenome.org/gene/510516:AO090005000973 ^@ http://purl.uniprot.org/uniprot/Q2UR47 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/510516:AO090001000672 ^@ http://purl.uniprot.org/uniprot/Q2UMP7 ^@ Function|||Subcellular Location Annotation ^@ RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.|||nucleolus http://togogenome.org/gene/510516:AO090701000050 ^@ http://purl.uniprot.org/uniprot/Q2U9F5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase U48 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/510516:AO090020000077 ^@ http://purl.uniprot.org/uniprot/Q2U545 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.|||Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.|||Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mitochondrion|||Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.|||Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.|||nucleolus|||nucleoplasm http://togogenome.org/gene/510516:AO090001000631 ^@ http://purl.uniprot.org/uniprot/Q2UMT5 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090102000470 ^@ http://purl.uniprot.org/uniprot/Q2UAA8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/510516:AO090009000235 ^@ http://purl.uniprot.org/uniprot/Q2UUP3 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/510516:AO090003000990 ^@ http://purl.uniprot.org/uniprot/Q7Z9L3 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family.|||Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. It could also function biosynthetically as a transglycosylase (By similarity).|||Monomer.|||Secreted|||The combination of poor nutrition conditions and attachment of mycelia to a hydrophobic solid surface appears to be a major inducing factor. http://togogenome.org/gene/510516:AO090009000117 ^@ http://purl.uniprot.org/uniprot/Q2UUZ1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 17 family.|||Cell membrane|||Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation and also function biosynthetically as a transglycosylase (By similarity).|||The GPI-anchor is attached to the protein in the endoplasmic reticulum and serves to target the protein to the cell surface. There, the glucosamine-inositol phospholipid moiety is cleaved off and the GPI-modified mannoprotein is covalently attached via its lipidless GPI glycan remnant to the 1,6-beta-glucan of the outer cell wall layer (By similarity).|||cell wall http://togogenome.org/gene/510516:AO090138000089 ^@ http://purl.uniprot.org/uniprot/Q2U1U8 ^@ Similarity ^@ Belongs to the DNA/RNA non-specific endonuclease family. http://togogenome.org/gene/510516:AO090010000341 ^@ http://purl.uniprot.org/uniprot/Q2TX02 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/510516:AO090011000231 ^@ http://purl.uniprot.org/uniprot/Q2U0Z9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090701000270 ^@ http://purl.uniprot.org/uniprot/Q2U8W2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YSP2 family.|||Membrane http://togogenome.org/gene/510516:AO090026000744 ^@ http://purl.uniprot.org/uniprot/Q2UE66 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.|||Belongs to the DEAD box helicase family. DDX31/DBP7 subfamily.|||Present with 1460 molecules/cell in log phase SD medium.|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.|||nucleolus http://togogenome.org/gene/510516:AO090011000604 ^@ http://purl.uniprot.org/uniprot/Q2U036 ^@ Function|||Similarity ^@ Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.|||Belongs to the adaptor complexes large subunit family. http://togogenome.org/gene/510516:AO090009000149 ^@ http://purl.uniprot.org/uniprot/Q2UUW2 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family. Prx5 subfamily.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/510516:AO090026000541 ^@ http://purl.uniprot.org/uniprot/Q2UEP3 ^@ Similarity ^@ Belongs to the CNOT2/3/5 family. http://togogenome.org/gene/510516:AO090023000956 ^@ http://purl.uniprot.org/uniprot/Q2UG70 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WRB/GET1 family.|||Endoplasmic reticulum membrane|||Interacts with get3.|||Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. http://togogenome.org/gene/510516:AO090023000897 ^@ http://purl.uniprot.org/uniprot/Q2UGC1 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/510516:AO090102000125 ^@ http://purl.uniprot.org/uniprot/Q2UB37 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090003000924 ^@ http://purl.uniprot.org/uniprot/Q2UK75 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/510516:AO090003000661 ^@ http://purl.uniprot.org/uniprot/Q2UKV4 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Homotetramer. http://togogenome.org/gene/510516:AO090020000627 ^@ http://purl.uniprot.org/uniprot/Q2U3T3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MAD2 family.|||Nucleus http://togogenome.org/gene/510516:AO090103000105 ^@ http://purl.uniprot.org/uniprot/Q2TYU7 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/510516:AO090026000158 ^@ http://purl.uniprot.org/uniprot/Q2UFL5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion.|||Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane.|||Mitochondrion matrix http://togogenome.org/gene/510516:AO090102000361 ^@ http://purl.uniprot.org/uniprot/Q2UAJ3 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 3 family.|||Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. http://togogenome.org/gene/510516:AO090701000847 ^@ http://purl.uniprot.org/uniprot/Q2U7G6 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/510516:AO090701000557 ^@ http://purl.uniprot.org/uniprot/Q2U860 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Mitochondrion http://togogenome.org/gene/510516:AO090005000520 ^@ http://purl.uniprot.org/uniprot/Q2US93 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/510516:AO090103000121 ^@ http://purl.uniprot.org/uniprot/Q2TYT1 ^@ Similarity ^@ Belongs to the RdRP family. http://togogenome.org/gene/510516:AO090005001148 ^@ http://purl.uniprot.org/uniprot/Q2UQQ4 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/510516:AO090701000277 ^@ http://purl.uniprot.org/uniprot/Q2U8V6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090010000078 ^@ http://purl.uniprot.org/uniprot/Q2TXN2 ^@ Similarity ^@ Belongs to the NmrA-type oxidoreductase family. http://togogenome.org/gene/510516:AO090026000185 ^@ http://purl.uniprot.org/uniprot/Q2UFJ3 ^@ Similarity ^@ Belongs to the SH3RF family. http://togogenome.org/gene/510516:AO090020000668 ^@ http://purl.uniprot.org/uniprot/Q2U3Q2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090001000049 ^@ http://purl.uniprot.org/uniprot/Q2UPA3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090011000953 ^@ http://purl.uniprot.org/uniprot/Q2TZ88 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090009000329 ^@ http://purl.uniprot.org/uniprot/Q2UUG0 ^@ Similarity ^@ Belongs to the CSN7/EIF3M family. CSN7 subfamily. http://togogenome.org/gene/510516:AO090003001424 ^@ http://purl.uniprot.org/uniprot/Q2UIY7 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/510516:AO090005001244 ^@ http://purl.uniprot.org/uniprot/Q2UQH5 ^@ Similarity ^@ Belongs to the amidase family. http://togogenome.org/gene/510516:AO090672000005 ^@ http://purl.uniprot.org/uniprot/Q2UG17 ^@ Similarity ^@ Belongs to the complex I 20 kDa subunit family. http://togogenome.org/gene/510516:AO090009000234 ^@ http://purl.uniprot.org/uniprot/Q2UUP4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycosyltransferase 28 family.|||Endoplasmic reticulum|||Heterodimer with ALG14 to form a functional enzyme.|||Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. http://togogenome.org/gene/510516:AO090009000643 ^@ http://purl.uniprot.org/uniprot/Q2UTQ0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ELP3 family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. http://togogenome.org/gene/510516:AO090005001262 ^@ http://purl.uniprot.org/uniprot/Q2UQG2 ^@ Similarity ^@ Belongs to the Cdt1 family. http://togogenome.org/gene/510516:AO090701000002 ^@ http://purl.uniprot.org/uniprot/Q8NKB6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A1 family.|||Cell membrane|||Probable GPI-anchored aspartic-type endopeptidase. http://togogenome.org/gene/510516:AO090005001591 ^@ http://purl.uniprot.org/uniprot/Q2UPL9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UTP25 family.|||Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.|||DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.|||nucleolus http://togogenome.org/gene/510516:AO090003001003 ^@ http://purl.uniprot.org/uniprot/Q2UK04 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/510516:AO090005000277 ^@ http://purl.uniprot.org/uniprot/Q2USV6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the esterase D family.|||Cytoplasm|||Serine hydrolase involved in the detoxification of formaldehyde. http://togogenome.org/gene/510516:AO090020000349 ^@ http://purl.uniprot.org/uniprot/Q8NK83 ^@ Activity Regulation|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically inhibited by 3'-phosphoadenosine 5'-phosphosulfate (PAPS).|||Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.|||Cytoplasm|||Homohexamer. Dimer of trimers.|||In the C-terminal section; belongs to the APS kinase family.|||In the N-terminal section; belongs to the sulfate adenylyltransferase family.|||The adenylyl-sulfate kinase (APS kinase) is non-functional. It is involved in allosteric regulation by PAPS. PAPS binding induces a large rotational rearrangement of domains lowering the substrate affinity of the enzyme. http://togogenome.org/gene/510516:AO090003000425 ^@ http://purl.uniprot.org/uniprot/Q2ULG0 ^@ Similarity ^@ Belongs to the adaptor complexes small subunit family. http://togogenome.org/gene/510516:AO090011000338 ^@ http://purl.uniprot.org/uniprot/Q2U0R1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL30 family. http://togogenome.org/gene/510516:AO090005001124 ^@ http://purl.uniprot.org/uniprot/Q2UQS2 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090023000425 ^@ http://purl.uniprot.org/uniprot/Q2UHJ3 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/510516:AO090005001105 ^@ http://purl.uniprot.org/uniprot/Q2UQU0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/510516:AO090026000688 ^@ http://purl.uniprot.org/uniprot/Q2UEB5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF10 family.|||Nucleus http://togogenome.org/gene/510516:AO090003000015 ^@ http://purl.uniprot.org/uniprot/Q2UMG0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090011000602 ^@ http://purl.uniprot.org/uniprot/Q2U038 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the kynureninase family.|||Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/510516:AO090003000917 ^@ http://purl.uniprot.org/uniprot/Q2UK82 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS8 family. http://togogenome.org/gene/510516:AO090005001386 ^@ http://purl.uniprot.org/uniprot/Q2UQ54 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).|||Belongs to the VPS51 family.|||Component of the Golgi-associated retrograde protein (GARP) complex.|||trans-Golgi network http://togogenome.org/gene/510516:AO090009000479 ^@ http://purl.uniprot.org/uniprot/Q2UU32 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000498 ^@ http://purl.uniprot.org/uniprot/Q2USB2 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. http://togogenome.org/gene/510516:AO090120000422 ^@ http://purl.uniprot.org/uniprot/Q2U613 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.|||Belongs to the DNA polymerase alpha subunit B family.|||Nucleus http://togogenome.org/gene/510516:AO090011000368 ^@ http://purl.uniprot.org/uniprot/Q2U0N3 ^@ Biotechnology|||Function|||Induction|||Similarity ^@ 4-methyl-2-oxopentanoate (MOA) reductase that reduces MOA, a possible intermediate in leucine synthesis, to D-leucate in a NADPH- or NADH-dependent manner, but with a preference for NADPH (PubMed:26615399). In addition to MOA, shows broad substrate specificity toward 2-keto acids (PubMed:26615399).|||Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Ethyl-2-hydroxy-4-methylpentanoate (ethyl leucate) contributes to a fruity flavor in Japanese sake and the strain overexpressing morA would help to ferment high-quality sake with an excellent flavor.|||Leucine and 4-methyl-2-oxopentanate (MOA) increase the expression 3.1- and 4.5-fold, respectively, whereas leucate represses the expression. http://togogenome.org/gene/510516:AO090011000428 ^@ http://purl.uniprot.org/uniprot/Q2U0I4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090001000496 ^@ http://purl.uniprot.org/uniprot/Q2UN58 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090023000710 ^@ http://purl.uniprot.org/uniprot/Q2UGU3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SPT5 family.|||Component of the spt4-spt5 complex. Interacts with RNA polymerase II (By similarity).|||Nucleus|||The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity). http://togogenome.org/gene/510516:AO090038000244 ^@ http://purl.uniprot.org/uniprot/Q2U306 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF4 family.|||Membrane http://togogenome.org/gene/510516:AO090011000326 ^@ http://purl.uniprot.org/uniprot/Q2U0S3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Peroxisome http://togogenome.org/gene/510516:AO090026000166 ^@ http://purl.uniprot.org/uniprot/Q2UFK7 ^@ Subcellular Location Annotation|||Subunit ^@ Component of the mitochondrial large ribosomal subunit.|||Mitochondrion http://togogenome.org/gene/510516:AO090023000105 ^@ http://purl.uniprot.org/uniprot/Q2UID1 ^@ Similarity ^@ Belongs to the FHIP family. http://togogenome.org/gene/510516:AO090011000850 ^@ http://purl.uniprot.org/uniprot/Q2TZH5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL14 family. http://togogenome.org/gene/510516:AO090003001488 ^@ http://purl.uniprot.org/uniprot/Q2UIT5 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.|||In the C-terminal section; belongs to the MoeA family.|||In the N-terminal section; belongs to the MoaB/Mog family. http://togogenome.org/gene/510516:AO090012000227 ^@ http://purl.uniprot.org/uniprot/Q2UDC5 ^@ Similarity ^@ Belongs to the PhyH family. http://togogenome.org/gene/510516:AO090003000972 ^@ http://purl.uniprot.org/uniprot/Q2UK33 ^@ Similarity ^@ Belongs to the peptidase M28 family. M28B subfamily. http://togogenome.org/gene/510516:AO090003000480 ^@ http://purl.uniprot.org/uniprot/Q2ULA9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF9 family.|||Nucleus http://togogenome.org/gene/510516:AO090102000063 ^@ http://purl.uniprot.org/uniprot/Q2UB91 ^@ Similarity ^@ Belongs to the amino acid/polyamine transporter 2 family. http://togogenome.org/gene/510516:AO090023000727 ^@ http://purl.uniprot.org/uniprot/Q2UGS7 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/510516:AO090026000816 ^@ http://purl.uniprot.org/uniprot/Q2UDZ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit M family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm http://togogenome.org/gene/510516:AO090020000372 ^@ http://purl.uniprot.org/uniprot/Q2U4E8 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/510516:AO090005001041 ^@ http://purl.uniprot.org/uniprot/Q2UQZ5 ^@ Disruption Phenotype|||Function|||Induction|||Subcellular Location Annotation ^@ BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (By similarity). They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity). Binds promoters of target genes at brlA response elements (BREs) containing the conserved sequence 5'-(C/A)(A/G)AGGG(G/A)-3' (By similarity). Required for conidiophores formation (PubMed:17213655). Controls expression of abaA (PubMed:19850144).|||Expression is controlled by flbA, flbS and fluG (PubMed:19850144).|||Leads to delayed conidia development (PubMed:17213655, PubMed:19850144).|||Nucleus http://togogenome.org/gene/510516:AO090020000625 ^@ http://purl.uniprot.org/uniprot/Q2U3T5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Nucleus http://togogenome.org/gene/510516:AO090701000212 ^@ http://purl.uniprot.org/uniprot/Q2U915 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRM CWC2 family.|||Nucleus http://togogenome.org/gene/510516:AO090138000055 ^@ http://purl.uniprot.org/uniprot/Q2U1X8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 43 family.|||Endo-1,5-alpha-L-arabinanase involved in degradation of pectin. Its preferred substrate is linear 1,5-alpha-L-arabinan (By similarity).|||Secreted http://togogenome.org/gene/510516:AO090023000688 ^@ http://purl.uniprot.org/uniprot/Q2UGW1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090001000572 ^@ http://purl.uniprot.org/uniprot/Q2UMY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FMP52 family.|||Mitochondrion outer membrane http://togogenome.org/gene/510516:AO090102000149 ^@ http://purl.uniprot.org/uniprot/Q2UB17 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ESF2/ABP1 family.|||Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity).|||nucleolus http://togogenome.org/gene/510516:AO090038000317 ^@ http://purl.uniprot.org/uniprot/Q2U2U3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/510516:AO090003000496 ^@ http://purl.uniprot.org/uniprot/Q2UL95 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090020000234 ^@ http://purl.uniprot.org/uniprot/Q2U4R4 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.|||In the C-terminal section; belongs to the MoeA family.|||In the N-terminal section; belongs to the MoaB/Mog family. http://togogenome.org/gene/510516:AO090005001192 ^@ http://purl.uniprot.org/uniprot/Q2UQL9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090005001302 ^@ http://purl.uniprot.org/uniprot/Q2UQC8 ^@ Function|||Similarity ^@ Belongs to the SHMT family.|||Interconversion of serine and glycine. http://togogenome.org/gene/510516:AO090012000176 ^@ http://purl.uniprot.org/uniprot/Q2UDG9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090001000357 ^@ http://purl.uniprot.org/uniprot/Q2UNI1 ^@ Similarity ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. http://togogenome.org/gene/510516:AO090026000803 ^@ http://purl.uniprot.org/uniprot/Q2UE11 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family. BCS1 subfamily.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090023000536 ^@ http://purl.uniprot.org/uniprot/Q2UH92 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ZIP transporter (TC 2.A.5) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/510516:AO090011000876 ^@ http://purl.uniprot.org/uniprot/Q2TZF0 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/510516:AO090206000015 ^@ http://purl.uniprot.org/uniprot/Q2PIY2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the COX16 family.|||Mitochondrion inner membrane|||Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. http://togogenome.org/gene/510516:AO090001000661 ^@ http://purl.uniprot.org/uniprot/Q2UMQ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFS4 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090012000475 ^@ http://purl.uniprot.org/uniprot/Q2UCR8 ^@ Function|||Similarity ^@ Belongs to the diphthine synthase family.|||S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis. http://togogenome.org/gene/510516:AO090001000189 ^@ http://purl.uniprot.org/uniprot/Q2UNX8 ^@ Biotechnology|||Domain|||Function|||Similarity|||Subunit ^@ AOL adopts the six-bladed beta-propeller fold and contains 6 binding sites per monomer, each located between two adjacent blades (PubMed:27318092, PubMed:28041800). The 6 binding sites that are non-equivalent, and owing to minor differences in amino-acid composition they exhibit a marked difference in specific ligand recognition (PubMed:27318092, PubMed:28041800).|||Belongs to the fungal fucose-specific lectin family.|||Homodimer (PubMed:17383961).|||Lectin that specifically binds to L-fucose and weakly reacts with mannose and N-acetyl-neuraminic acid (PubMed:12092808, PubMed:27318092, PubMed:28041800). Has strongest preference for the alpha-1,6-fucosylated chain (core fucose) on glycoproteins among alpha-1,2-, alpha-1,3-, alpha-1,4-, and alpha-1,6-fucosylated chains (PubMed:17383961, PubMed:19109923). Binds to fucose residues of IgE in mice and human, causing antigen-independent IgE-mediated mast cell activation and anaphylactoid reactions in mice and is possibly implicated in allergic response to Aspergillus oryzae in humans (PubMed:21790704). Induces secretion of pro-inflammatory cytokines IL6 and IL8 implicated in ocular diseases such as mycotic keratitis, probably through its interaction with host toll-like receptors TLR2 and TLR4, followed by up-regulation of pro-inflammatory cytokines (PubMed:28470344).|||Lectins have particular value as specific probes for investigating the distribution, structure and biological function of carbohydrate chains on the cell surface of animal, plant, and microorganism because of their specificity for defined carbohydrate structures (PubMed:17383961). FleA is suitable for detecting core fucose on cell surface glycoproteins and/or a useful vehicle for delivery of substances to the inside of cells (PubMed:17383961, PubMed:21892597). http://togogenome.org/gene/510516:AO090012000528 ^@ http://purl.uniprot.org/uniprot/Q2UCM3 ^@ Similarity ^@ Belongs to the spermidine/spermine synthase family. http://togogenome.org/gene/510516:AO090010000654 ^@ http://purl.uniprot.org/uniprot/Q2TW91 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 72 family.|||Cell membrane|||Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in cell wall morphogenesis. http://togogenome.org/gene/510516:AO090009000589 ^@ http://purl.uniprot.org/uniprot/Q2UTU5 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/510516:AO090005000588 ^@ http://purl.uniprot.org/uniprot/Q2US34 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/510516:AO090020000517 ^@ http://purl.uniprot.org/uniprot/Q2U428 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/510516:AO090124000083 ^@ http://purl.uniprot.org/uniprot/Q2U734 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family. http://togogenome.org/gene/510516:AO090020000345 ^@ http://purl.uniprot.org/uniprot/Q2U4H1 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/510516:AO090001000704 ^@ http://purl.uniprot.org/uniprot/Q2UMM1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090026000029 ^@ http://purl.uniprot.org/uniprot/Q2UFY6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090120000371 ^@ http://purl.uniprot.org/uniprot/Q2U657 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/510516:AO090003000189 ^@ http://purl.uniprot.org/uniprot/Q2UM10 ^@ Function|||Similarity ^@ Belongs to the transferase hexapeptide repeat family.|||Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint. http://togogenome.org/gene/510516:AO090166000095 ^@ http://purl.uniprot.org/uniprot/Q2U9M2 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. http://togogenome.org/gene/510516:AO090138000196 ^@ http://purl.uniprot.org/uniprot/Q2U1K8 ^@ Similarity ^@ Belongs to the FAH family. http://togogenome.org/gene/510516:AO090103000166 ^@ http://purl.uniprot.org/uniprot/Q2TYP4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090012000950 ^@ http://purl.uniprot.org/uniprot/Q2UBL4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS4 family. http://togogenome.org/gene/510516:AO090005000482 ^@ http://purl.uniprot.org/uniprot/Q2USC5 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/510516:AO090010000392 ^@ http://purl.uniprot.org/uniprot/Q2TWW0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090102000079 ^@ http://purl.uniprot.org/uniprot/Q2UB76 ^@ Similarity ^@ Belongs to the peptidase S28 family. http://togogenome.org/gene/510516:AO090701000034 ^@ http://purl.uniprot.org/uniprot/Q2U9H0 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/510516:AO090038000565 ^@ http://purl.uniprot.org/uniprot/Q2U282 ^@ Similarity ^@ Belongs to the NAPRTase family. http://togogenome.org/gene/510516:AO090120000080 ^@ http://purl.uniprot.org/uniprot/Q9Y713 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/510516:AO090011000904 ^@ http://purl.uniprot.org/uniprot/Q2TZD0 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/510516:AO090001000630 ^@ http://purl.uniprot.org/uniprot/Q2UMT6 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/510516:AO090001000307 ^@ http://purl.uniprot.org/uniprot/Q2UNM3 ^@ Similarity ^@ Belongs to the LOR family. http://togogenome.org/gene/510516:AO090701000838 ^@ http://purl.uniprot.org/uniprot/Q2U7H4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/510516:AO090020000670 ^@ http://purl.uniprot.org/uniprot/Q2U3Q0 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/510516:AO090023000696 ^@ http://purl.uniprot.org/uniprot/Q2UGV4 ^@ Similarity ^@ Belongs to the SMP-30/CGR1 family. http://togogenome.org/gene/510516:AO090701000175 ^@ http://purl.uniprot.org/uniprot/Q2U948 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/510516:AO090103000039 ^@ http://purl.uniprot.org/uniprot/Q2TZ00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ORC3 family.|||Nucleus http://togogenome.org/gene/510516:AO090010000607 ^@ http://purl.uniprot.org/uniprot/Q2TWD3 ^@ Similarity ^@ Belongs to the multicopper oxidase family. http://togogenome.org/gene/510516:AO090001000193 ^@ http://purl.uniprot.org/uniprot/Q2UNX5 ^@ Function|||Similarity ^@ Belongs to the helicase family. Dicer subfamily.|||Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons (By similarity). http://togogenome.org/gene/510516:AO090009000153 ^@ http://purl.uniprot.org/uniprot/Q2UUW0 ^@ Similarity ^@ Belongs to the NmrA-type oxidoreductase family. http://togogenome.org/gene/510516:AO090009000593 ^@ http://purl.uniprot.org/uniprot/Q2UTU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20A family.|||Secreted http://togogenome.org/gene/510516:AO090012000079 ^@ http://purl.uniprot.org/uniprot/Q2UDQ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090001000086 ^@ http://purl.uniprot.org/uniprot/Q2UP74 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 72 family.|||Cell membrane|||Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in cell wall morphogenesis. http://togogenome.org/gene/510516:AO090010000505 ^@ http://purl.uniprot.org/uniprot/Q2TWM0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster.|||Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.|||Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090026000130 ^@ http://purl.uniprot.org/uniprot/Q2UFP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERG4/ERG24 family.|||Membrane http://togogenome.org/gene/510516:AO090012000416 ^@ http://purl.uniprot.org/uniprot/Q2UCW8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090010000030 ^@ http://purl.uniprot.org/uniprot/Q2TXS4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 1 family.|||Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.|||Secreted http://togogenome.org/gene/510516:AO090026000794 ^@ http://purl.uniprot.org/uniprot/Q2UE18 ^@ Similarity ^@ Belongs to the TPA1 family. http://togogenome.org/gene/510516:AO090102000382 ^@ http://purl.uniprot.org/uniprot/Q2UAH5 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/510516:AO090003000859 ^@ http://purl.uniprot.org/uniprot/Q2UKD0 ^@ Function|||Similarity ^@ Belongs to the aldo/keto reductase family.|||Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway (By similarity). http://togogenome.org/gene/510516:AO090701000809 ^@ http://purl.uniprot.org/uniprot/Q2U7K0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003000824 ^@ http://purl.uniprot.org/uniprot/Q2UKF9 ^@ Similarity ^@ Belongs to the VPS8 family. http://togogenome.org/gene/510516:AO090001000300 ^@ http://purl.uniprot.org/uniprot/Q2UNM8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA8 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090103000052 ^@ http://purl.uniprot.org/uniprot/Q2TYY8 ^@ Similarity ^@ Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family. http://togogenome.org/gene/510516:AO090005000352 ^@ http://purl.uniprot.org/uniprot/Q2USP0 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.|||Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. http://togogenome.org/gene/510516:AO090003000280 ^@ http://purl.uniprot.org/uniprot/Q2ULT1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activates the atg1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy. Also involved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation. Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy. Finally, atg13 is also required for glycogen storage during stationary phase (By similarity).|||Belongs to the ATG13 family. Fungi subfamily.|||Cytoplasm|||Interacts with atg1 to form the atg1-atg13 kinase complex.|||Preautophagosomal structure http://togogenome.org/gene/510516:AO090103000033 ^@ http://purl.uniprot.org/uniprot/Q2TZ06 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SIP5 family.|||Cytoplasm|||May negatively regulate the snf1 kinase. http://togogenome.org/gene/510516:AO090020000148 ^@ http://purl.uniprot.org/uniprot/Q2U4Y8 ^@ Similarity ^@ Belongs to the polyketide transferase af380 family. http://togogenome.org/gene/510516:AO090001000584 ^@ http://purl.uniprot.org/uniprot/Q2UMX4 ^@ Function|||Similarity ^@ Belongs to the inositol monophosphatase superfamily.|||Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. http://togogenome.org/gene/510516:AO090011000370 ^@ http://purl.uniprot.org/uniprot/Q2U0N1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090020000036 ^@ http://purl.uniprot.org/uniprot/Q2U582 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000315 ^@ http://purl.uniprot.org/uniprot/Q2USS1 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/510516:AO090009000355 ^@ http://purl.uniprot.org/uniprot/Q2UUD7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FIT family. Fungal FIT2B/SCS3 subfamily.|||Endoplasmic reticulum membrane|||Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates in the endoplasmic reticulum (ER) lumen. This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis. May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation. May play a role in the regulation of cell morphology and cytoskeletal organization. Involved in phospholipid biosynthesis.|||Membrane http://togogenome.org/gene/510516:AO090012000408 ^@ http://purl.uniprot.org/uniprot/Q2UCX6 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/510516:AO090020000324 ^@ http://purl.uniprot.org/uniprot/Q2U4I9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090102000577 ^@ http://purl.uniprot.org/uniprot/Q2UA20 ^@ Similarity ^@ Belongs to the eukaryotic AdoMetDC family. http://togogenome.org/gene/510516:AO090023000723 ^@ http://purl.uniprot.org/uniprot/Q2UGT1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 8 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/510516:AO090023000757 ^@ http://purl.uniprot.org/uniprot/Q2UGQ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with the respiratory chain complex III/complex IV supercomplex.|||Belongs to the RCF1 family.|||Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.|||Mitochondrion membrane http://togogenome.org/gene/510516:AO090005000815 ^@ http://purl.uniprot.org/uniprot/Q2URI5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily. http://togogenome.org/gene/510516:AO090103000248 ^@ http://purl.uniprot.org/uniprot/Q2TYH1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000968 ^@ http://purl.uniprot.org/uniprot/Q2UR51 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090020000575 ^@ http://purl.uniprot.org/uniprot/Q2U3X8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family. http://togogenome.org/gene/510516:AO090026000843 ^@ http://purl.uniprot.org/uniprot/Q2UDX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS41 family.|||Mitochondrion http://togogenome.org/gene/510516:AO090026000345 ^@ http://purl.uniprot.org/uniprot/Q2UF52 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/510516:AO090103000342 ^@ http://purl.uniprot.org/uniprot/Q2TY91 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/510516:AO090012000945 ^@ http://purl.uniprot.org/uniprot/Q2UBL9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090011000149 ^@ http://purl.uniprot.org/uniprot/Q2U168 ^@ Similarity ^@ Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. http://togogenome.org/gene/510516:AO090120000188 ^@ http://purl.uniprot.org/uniprot/Q2U6L5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM234 family.|||Membrane http://togogenome.org/gene/510516:AO090113000038 ^@ http://purl.uniprot.org/uniprot/Q2U5R5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003000051 ^@ http://purl.uniprot.org/uniprot/Q2UMC7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.|||Catalyzes the hydrolysis of ATP coupled with the transport of calcium.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/510516:AO090012000870 ^@ http://purl.uniprot.org/uniprot/Q2UBT7 ^@ Similarity ^@ Belongs to the profilin family. http://togogenome.org/gene/510516:AO090023000510 ^@ http://purl.uniprot.org/uniprot/Q2UHB7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent RNA helicase required for ribosome biogenesis. Involved in the release of U14 snoRNA in pre-ribosomal complexes. Required for pre-rRNA cleavage at site A2 (By similarity).|||Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily.|||Interacts with the U3 and U14 snoRNAs. Associates with pre-ribosomal complexes (By similarity).|||The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.|||nucleolus http://togogenome.org/gene/510516:AO090005001441 ^@ http://purl.uniprot.org/uniprot/Q2UQ02 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/510516:AO090023000997 ^@ http://purl.uniprot.org/uniprot/Q2UG33 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL3 family. http://togogenome.org/gene/510516:AO090038000376 ^@ http://purl.uniprot.org/uniprot/Q2U2P3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GOSR1 family.|||Component of several multiprotein Golgi SNARE complexes.|||Golgi apparatus membrane|||Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.|||Membrane http://togogenome.org/gene/510516:AO090038000442 ^@ http://purl.uniprot.org/uniprot/Q2U2I5 ^@ Function ^@ Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway. http://togogenome.org/gene/510516:AO090003001411 ^@ http://purl.uniprot.org/uniprot/Q2UJ00 ^@ Similarity ^@ Belongs to the amidase family. http://togogenome.org/gene/510516:AO090038000333 ^@ http://purl.uniprot.org/uniprot/Q2U2S9 ^@ Function|||Similarity ^@ Belongs to the APS kinase family.|||Catalyzes the synthesis of activated sulfate. http://togogenome.org/gene/510516:AO090701000664 ^@ http://purl.uniprot.org/uniprot/Q2U7X5 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. http://togogenome.org/gene/510516:AO090023000318 ^@ http://purl.uniprot.org/uniprot/Q2UHT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.|||Membrane http://togogenome.org/gene/510516:AO090020000207 ^@ http://purl.uniprot.org/uniprot/Q2U4T9 ^@ Caution|||Similarity ^@ Belongs to the glycosyl hydrolase 18 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/510516:AO090009000680 ^@ http://purl.uniprot.org/uniprot/Q2UTL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ESS2 family.|||Nucleus http://togogenome.org/gene/510516:AO090009000188 ^@ http://purl.uniprot.org/uniprot/Q2UUT2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the COQ9 family.|||Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.|||Mitochondrion http://togogenome.org/gene/510516:AO090020000058 ^@ http://purl.uniprot.org/uniprot/Q2U561 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SPT6 family.|||Nucleus|||Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression (By similarity). http://togogenome.org/gene/510516:AO090102000245 ^@ http://purl.uniprot.org/uniprot/Q2UAT8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fluoride exporter Fluc/FEX family.|||Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.|||Membrane http://togogenome.org/gene/510516:AO090003000501 ^@ http://purl.uniprot.org/uniprot/Q2UL91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TFIIA subunit 1 family.|||Nucleus http://togogenome.org/gene/510516:AO090166000068 ^@ http://purl.uniprot.org/uniprot/Q2U9P6 ^@ Similarity ^@ Belongs to the terpene cyclase/mutase family. http://togogenome.org/gene/510516:AO090005001482 ^@ http://purl.uniprot.org/uniprot/Q2UPW4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S9B family.|||Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.|||Vacuole membrane http://togogenome.org/gene/510516:AO090023000639 ^@ http://purl.uniprot.org/uniprot/Q2UH05 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090001000482 ^@ http://purl.uniprot.org/uniprot/Q2UN71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MET18/MMS19 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/510516:AO090005001240 ^@ http://purl.uniprot.org/uniprot/Q2UQH9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M24B family.|||Binds 2 manganese ions per subunit.|||Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides. http://togogenome.org/gene/510516:AO090001000462 ^@ http://purl.uniprot.org/uniprot/Q2UN88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GOLPH3/VPS74 family.|||Membrane http://togogenome.org/gene/510516:AO090009000067 ^@ http://purl.uniprot.org/uniprot/Q2UV32 ^@ Similarity ^@ Belongs to the multicopper oxidase family. http://togogenome.org/gene/510516:AO090011000605 ^@ http://purl.uniprot.org/uniprot/Q2U035 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CWC25 family.|||Nucleus http://togogenome.org/gene/510516:AO090120000137 ^@ http://purl.uniprot.org/uniprot/Q2U6Q5 ^@ Function|||Similarity ^@ Belongs to the eIF-1A family.|||Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. http://togogenome.org/gene/510516:AO090020000210 ^@ http://purl.uniprot.org/uniprot/Q2U4T6 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/510516:AO090003000310 ^@ http://purl.uniprot.org/uniprot/Q2ULQ6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the alternative oxidase family.|||Binds 2 iron ions per subunit.|||Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.|||Mitochondrion inner membrane http://togogenome.org/gene/510516:AO090003001329 ^@ http://purl.uniprot.org/uniprot/Q2UJ75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HSF family.|||Nucleus http://togogenome.org/gene/510516:AO090701000145 ^@ http://purl.uniprot.org/uniprot/Q2U972 ^@ Similarity ^@ Belongs to the MAK16 family. http://togogenome.org/gene/510516:AO090005000605 ^@ http://purl.uniprot.org/uniprot/Q2US18 ^@ Similarity ^@ Belongs to the CBF/MAK21 family. http://togogenome.org/gene/510516:AO090010000477 ^@ http://purl.uniprot.org/uniprot/Q2TWP4 ^@ Similarity ^@ Belongs to the UPF0057 (PMP3) family. http://togogenome.org/gene/510516:AO090012000084 ^@ http://purl.uniprot.org/uniprot/Q2UDQ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the chitin synthase family.|||Cell membrane|||Membrane|||Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer. http://togogenome.org/gene/510516:AO090005001018 ^@ http://purl.uniprot.org/uniprot/Q2UR12 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruD family. http://togogenome.org/gene/510516:AO090003000212 ^@ http://purl.uniprot.org/uniprot/Q2ULZ1 ^@ Similarity ^@ Belongs to the GST superfamily. Zeta family. http://togogenome.org/gene/510516:AO090003000668 ^@ http://purl.uniprot.org/uniprot/Q2UKU7 ^@ Similarity ^@ Belongs to the ATP-dependent DNA ligase family. http://togogenome.org/gene/510516:AO090001000459 ^@ http://purl.uniprot.org/uniprot/Q2UN89 ^@ Similarity ^@ Belongs to the complex I 23 kDa subunit family. http://togogenome.org/gene/510516:AO090005001157 ^@ http://purl.uniprot.org/uniprot/Q2UQP7 ^@ Similarity ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. http://togogenome.org/gene/510516:AO090023000164 ^@ http://purl.uniprot.org/uniprot/Q2UI75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sorting nexin family.|||Endosome membrane|||Membrane http://togogenome.org/gene/510516:AO090001000133 ^@ http://purl.uniprot.org/uniprot/Q2UP32 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 28 family.|||Secreted|||Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates. http://togogenome.org/gene/510516:AO090005000760 ^@ http://purl.uniprot.org/uniprot/Q2URM9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SEC23/SEC24 family. SEC23 subfamily.|||COPII-coated vesicle membrane|||Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).|||Cytoplasm|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||The COPII coat is composed of at least 5 proteins: the sec23/24 complex, the sec13/31 complex, and the protein sar1. http://togogenome.org/gene/510516:AO090102000532 ^@ http://purl.uniprot.org/uniprot/Q2UA59 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090701000789 ^@ http://purl.uniprot.org/uniprot/Q2U7L7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the acid sphingomyelinase family.|||Binds 2 Zn(2+) ions per subunit.|||Converts sphingomyelin to ceramide. http://togogenome.org/gene/510516:AO090011000918 ^@ http://purl.uniprot.org/uniprot/Q2TZB8 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/510516:AO090011000813 ^@ http://purl.uniprot.org/uniprot/Q2TZK9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.|||Membrane http://togogenome.org/gene/510516:AO090020000067 ^@ http://purl.uniprot.org/uniprot/Q2U554 ^@ Function|||Similarity ^@ Belongs to the WD repeat EIF2A family.|||Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. http://togogenome.org/gene/510516:AO090701000274 ^@ http://purl.uniprot.org/uniprot/Q2U8V9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/510516:AO090023000220 ^@ http://purl.uniprot.org/uniprot/Q2UI23 ^@ Similarity|||Subunit ^@ Belongs to the SKP1 family.|||Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes. http://togogenome.org/gene/510516:AO090026000458 ^@ http://purl.uniprot.org/uniprot/Q2UEV9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL3 family. http://togogenome.org/gene/510516:AO090003000630 ^@ http://purl.uniprot.org/uniprot/Q2UKX7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090003000174 ^@ http://purl.uniprot.org/uniprot/Q2UM22 ^@ Similarity ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. http://togogenome.org/gene/510516:AO090012000725 ^@ http://purl.uniprot.org/uniprot/Q2UC62 ^@ Similarity ^@ Belongs to the alkaline phosphatase family. http://togogenome.org/gene/510516:AO090003001343 ^@ http://purl.uniprot.org/uniprot/Q2UJ62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CSC1 (TC 1.A.17) family.|||Membrane http://togogenome.org/gene/510516:AO090009000092 ^@ http://purl.uniprot.org/uniprot/Q2UV13 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/510516:AO090020000403 ^@ http://purl.uniprot.org/uniprot/Q2U4C2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.|||Cell membrane|||The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses. http://togogenome.org/gene/510516:AO090120000348 ^@ http://purl.uniprot.org/uniprot/Q2U678 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruB family. http://togogenome.org/gene/510516:AO090005001652 ^@ http://purl.uniprot.org/uniprot/Q2UPG4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ALAD family.|||Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.|||Homooctamer. http://togogenome.org/gene/510516:AO090011000648 ^@ http://purl.uniprot.org/uniprot/Q2U002 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit G family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.|||Cytoplasm|||RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. http://togogenome.org/gene/510516:AO090003001132 ^@ http://purl.uniprot.org/uniprot/Q2UJP2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS6 family. http://togogenome.org/gene/510516:AO090020000008 ^@ http://purl.uniprot.org/uniprot/Q2U5A7 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/510516:AO090103000082 ^@ http://purl.uniprot.org/uniprot/Q2TYW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.|||Membrane http://togogenome.org/gene/510516:AO090701000347 ^@ http://purl.uniprot.org/uniprot/Q2U8P3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000963 ^@ http://purl.uniprot.org/uniprot/Q2UR56 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090012000208 ^@ http://purl.uniprot.org/uniprot/Q2UDE2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.|||Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of nbp35 and two labile, bridging clusters between subunits of the nbp35-cfd1 heterotetramer.|||Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The nbp35-cfd1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.|||Cytoplasm|||Heterotetramer of 2 nbp35 and 2 cfd1 chains. http://togogenome.org/gene/510516:AO090026000561 ^@ http://purl.uniprot.org/uniprot/Q2UEM4 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/510516:AO090005001279 ^@ http://purl.uniprot.org/uniprot/Q2UQE8 ^@ Function|||Subcellular Location Annotation ^@ COPII-coated vesicle membrane|||Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/510516:AO090005001311 ^@ http://purl.uniprot.org/uniprot/Q2UQC2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/510516:AO090003000443 ^@ http://purl.uniprot.org/uniprot/Q2ULE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.|||Membrane http://togogenome.org/gene/510516:AO090026000404 ^@ http://purl.uniprot.org/uniprot/Q2UF05 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/510516:AO090102000127 ^@ http://purl.uniprot.org/uniprot/Q2UB35 ^@ Similarity ^@ Belongs to the PHF5 family. http://togogenome.org/gene/510516:AO090102000010 ^@ http://purl.uniprot.org/uniprot/Q2UBD9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pectinesterase family.|||Involved in maceration and soft-rotting of plant tissue.|||Secreted http://togogenome.org/gene/510516:AO090103000267 ^@ http://purl.uniprot.org/uniprot/Q2TYF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/510516:AO090120000079 ^@ http://purl.uniprot.org/uniprot/Q2U6V6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.|||Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||nucleolus http://togogenome.org/gene/510516:AO090023000223 ^@ http://purl.uniprot.org/uniprot/Q2UI20 ^@ Function|||Similarity ^@ Belongs to the queuosine salvage protein family.|||Involved in salvaging queuosine. http://togogenome.org/gene/510516:AO090005000736 ^@ http://purl.uniprot.org/uniprot/Q2URP9 ^@ Similarity ^@ Belongs to the REXO1/REXO3 family. http://togogenome.org/gene/510516:AO090005000614 ^@ http://purl.uniprot.org/uniprot/Q2US09 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EMC3 family.|||Membrane|||The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). http://togogenome.org/gene/510516:AO090010000051 ^@ http://purl.uniprot.org/uniprot/Q2TXQ5 ^@ Similarity ^@ Belongs to the arylamine N-acetyltransferase family. http://togogenome.org/gene/510516:AO090011000329 ^@ http://purl.uniprot.org/uniprot/Q2U0S0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/510516:AO090038000352 ^@ http://purl.uniprot.org/uniprot/Q2U2R2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase H subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/510516:AO090010000482 ^@ http://purl.uniprot.org/uniprot/Q2TWP0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/510516:AO090023000923 ^@ http://purl.uniprot.org/uniprot/Q2UG98 ^@ Similarity|||Subunit ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family.|||Homohexamer. http://togogenome.org/gene/510516:AO090102000111 ^@ http://purl.uniprot.org/uniprot/Q2UB48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxisomal membrane protein PXMP2/4 family.|||Membrane http://togogenome.org/gene/510516:AO090020000386 ^@ http://purl.uniprot.org/uniprot/Q2U4D5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090102000523 ^@ http://purl.uniprot.org/uniprot/Q2UA65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPCS3 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/510516:AO090023000749 ^@ http://purl.uniprot.org/uniprot/Q2UGR1 ^@ Function ^@ Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway. http://togogenome.org/gene/510516:AO090001000243 ^@ http://purl.uniprot.org/uniprot/Q2UNT1 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/510516:AO090005001213 ^@ http://purl.uniprot.org/uniprot/Q2UQK2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090005000361 ^@ http://purl.uniprot.org/uniprot/Q2USN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.|||Membrane http://togogenome.org/gene/510516:AO090010000776 ^@ http://purl.uniprot.org/uniprot/Q2TVY0 ^@ Similarity ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. http://togogenome.org/gene/510516:AO090011000595 ^@ http://purl.uniprot.org/uniprot/Q2U045 ^@ Similarity ^@ Belongs to the prephenate/arogenate dehydrogenase family. http://togogenome.org/gene/510516:AO090701000893 ^@ http://purl.uniprot.org/uniprot/Q2U7C5 ^@ Similarity ^@ Belongs to the PheA/TfdB FAD monooxygenase family. http://togogenome.org/gene/510516:AO090023000409 ^@ http://purl.uniprot.org/uniprot/Q2UHK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20A family.|||Secreted http://togogenome.org/gene/510516:AO090206000053 ^@ http://purl.uniprot.org/uniprot/Q2PIU9 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/510516:AO090009000568 ^@ http://purl.uniprot.org/uniprot/Q2UTW1 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/510516:AO090011000513 ^@ http://purl.uniprot.org/uniprot/Q2U0A9 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/510516:AO090011000589 ^@ http://purl.uniprot.org/uniprot/Q2U049 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL13 family. http://togogenome.org/gene/510516:AO090120000264 ^@ http://purl.uniprot.org/uniprot/Q2U6E9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/510516:AO090003001345 ^@ http://purl.uniprot.org/uniprot/Q2UJ60 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/510516:AO090011000291 ^@ http://purl.uniprot.org/uniprot/Q2U0V4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane. Modulates the mitochondrial matrix zinc pool (By similarity).|||Belongs to the complex I LYR family. MZM1 subfamily.|||Interacts with RIP1.|||Mitochondrion matrix http://togogenome.org/gene/510516:AO090103000214 ^@ http://purl.uniprot.org/uniprot/Q2TYK0 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/510516:AO090009000454 ^@ http://purl.uniprot.org/uniprot/Q2UU54 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GINS1/PSF1 family.|||Component of the GINS complex.|||Nucleus|||Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.|||The GINS complex plays an essential role in the initiation of DNA replication. http://togogenome.org/gene/510516:AO090020000103 ^@ http://purl.uniprot.org/uniprot/Q2U527 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/510516:AO090005000532 ^@ http://purl.uniprot.org/uniprot/Q2US82 ^@ Similarity ^@ Belongs to the PAL/histidase family. http://togogenome.org/gene/510516:AO090026000472 ^@ http://purl.uniprot.org/uniprot/Q2UEU9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.|||Belongs to the peptidase S16 family.|||Homohexamer or homoheptamer. Organized in a ring with a central cavity.|||Mitochondrion matrix http://togogenome.org/gene/510516:AO090012000469 ^@ http://purl.uniprot.org/uniprot/Q2UCS2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090005000110 ^@ http://purl.uniprot.org/uniprot/Q2UT91 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090038000064 ^@ http://purl.uniprot.org/uniprot/Q2U3F2 ^@ Similarity ^@ Belongs to the NmrA-type oxidoreductase family. http://togogenome.org/gene/510516:AO090012000623 ^@ http://purl.uniprot.org/uniprot/Q2UCE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Cell membrane|||Membrane http://togogenome.org/gene/510516:AO090009000609 ^@ http://purl.uniprot.org/uniprot/Q2UTS6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL5 family. http://togogenome.org/gene/510516:AO090001000093 ^@ http://purl.uniprot.org/uniprot/Q2UP67 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UbiD family. UbiD-like/FDC subfamily.|||Binds 1 prenylated FMN (prenyl-FMN) per subunit.|||Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites.|||Cytoplasm|||Homodimer. May form higher order oligomers. http://togogenome.org/gene/510516:AO090038000341 ^@ http://purl.uniprot.org/uniprot/Q2U2S3 ^@ Similarity ^@ Belongs to the CBF/MAK21 family. http://togogenome.org/gene/510516:AO090020000146 ^@ http://purl.uniprot.org/uniprot/Q2U4Z0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIM11 family.|||Membrane http://togogenome.org/gene/510516:AO090005001495 ^@ http://purl.uniprot.org/uniprot/Q2UPV3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090010000768 ^@ http://purl.uniprot.org/uniprot/Q2TVY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/510516:AO090701000187 ^@ http://purl.uniprot.org/uniprot/Q2U937 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-II family.|||Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.|||Mitochondrion http://togogenome.org/gene/510516:AO090012000638 ^@ http://purl.uniprot.org/uniprot/Q2UCD3 ^@ Similarity ^@ Belongs to the CAP family. http://togogenome.org/gene/510516:AO090038000334 ^@ http://purl.uniprot.org/uniprot/Q2U2S8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase C subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.|||V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex. http://togogenome.org/gene/510516:AO090701000784 ^@ http://purl.uniprot.org/uniprot/Q2U7M1 ^@ Subcellular Location Annotation ^@ Mitochondrion inner membrane|||Mitochondrion intermembrane space http://togogenome.org/gene/510516:AO090026000372 ^@ http://purl.uniprot.org/uniprot/Q2UF30 ^@ Similarity ^@ Belongs to the ATPase delta chain family. http://togogenome.org/gene/510516:AO090009000138 ^@ http://purl.uniprot.org/uniprot/Q2UUX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/510516:AO090010000161 ^@ http://purl.uniprot.org/uniprot/Q2TXG0 ^@ Function|||Similarity ^@ Belongs to the PrpD family.|||Cis-aconitate decarboxylase-like protein; part of the gene cluster that mediates the biosynthesis of oryzines, natural products with an unusual maleidride backbone (PubMed:30104550). The two subunits of the fungal fatty acid synthase oryfasA and oryfasB probably form octenoic acid (Probable). This fatty acid is most likely activated by the acyl-CoA ligase oryP to give octenyl-CoA before the citrate synthase-like protein oryE catalyzes condensation with oxaloacetate to form tricarboxylic acid (Probable). The next steps of the pathways are conjectural, but a favorite possible route has been proposed, beginning with decarboxylation and concomitant dehydration by the decarboxylase oryM, followed by tautomerization, which may lead to the production of a diene intermediate (Probable). Reduction of this diene intermediate could give the known metabolite piliformic acid (Probable). On the pathway to oryzine B and oryzine A, however, hydroxylation of the diene by the alpha-ketoglutarate-dependent dioxygenase oryG and lactonisation by the lactonohydrolases oryH or oryL could give oryzine B directly (Probable). Finally, enoyl reduction by the dehydrogenase oryD would then convert oryzine B into oryzine A (Probable). http://togogenome.org/gene/510516:AO090020000380 ^@ http://purl.uniprot.org/uniprot/Q2U4E0 ^@ Similarity ^@ Belongs to the NRP synthetase family. http://togogenome.org/gene/510516:AO090010000533 ^@ http://purl.uniprot.org/uniprot/Q2TWJ4 ^@ Similarity ^@ Belongs to the NmrA-type oxidoreductase family. http://togogenome.org/gene/510516:AO090012000418 ^@ http://purl.uniprot.org/uniprot/Q2UCW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/510516:AO090005000758 ^@ http://purl.uniprot.org/uniprot/Q2URN1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family. AK3 subfamily.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.|||Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.|||Mitochondrion matrix|||Monomer. http://togogenome.org/gene/510516:AO090001000298 ^@ http://purl.uniprot.org/uniprot/Q2UNN0 ^@ Subcellular Location Annotation ^@ Membrane