http://togogenome.org/gene/47853:HXZ27_RS27050 ^@ http://purl.uniprot.org/uniprot/A0A1C4UK87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/47853:HXZ27_RS21865 ^@ http://purl.uniprot.org/uniprot/A0A1C4X861 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily. http://togogenome.org/gene/47853:HXZ27_RS04900 ^@ http://purl.uniprot.org/uniprot/A0A1C5A7K7 ^@ Similarity ^@ Belongs to the UPRTase family. http://togogenome.org/gene/47853:HXZ27_RS26160 ^@ http://purl.uniprot.org/uniprot/A0A7H8XTL7 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/47853:HXZ27_RS23090 ^@ http://purl.uniprot.org/uniprot/A0A1C4Y527 ^@ PTM|||Subcellular Location Annotation|||Subunit ^@ Binds 2 heme c groups covalently per subunit.|||Cell membrane|||Membrane|||The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit. http://togogenome.org/gene/47853:HXZ27_RS29155 ^@ http://purl.uniprot.org/uniprot/A0A7H8XVH1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DisA family.|||Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.|||Homooctamer.|||Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions. http://togogenome.org/gene/47853:HXZ27_RS01955 ^@ http://purl.uniprot.org/uniprot/A0A1C4YZ00 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/47853:HXZ27_RS24765 ^@ http://purl.uniprot.org/uniprot/A0A1C4XN75 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/47853:HXZ27_RS11135 ^@ http://purl.uniprot.org/uniprot/A0A1C4ZG21 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/47853:HXZ27_RS24435 ^@ http://purl.uniprot.org/uniprot/A0A1C4XQK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/47853:HXZ27_RS25115 ^@ http://purl.uniprot.org/uniprot/A0A1C5ALU0 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/47853:HXZ27_RS22425 ^@ http://purl.uniprot.org/uniprot/A0A1C4XE70 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/47853:HXZ27_RS28755 ^@ http://purl.uniprot.org/uniprot/A0A1C4U3G8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS12550 ^@ http://purl.uniprot.org/uniprot/A0A1C5AV76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/47853:HXZ27_RS25805 ^@ http://purl.uniprot.org/uniprot/A0A7H8XTU5 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/47853:HXZ27_RS22710 ^@ http://purl.uniprot.org/uniprot/A0A1C4XGP8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CobB/CobQ family. GatD subfamily.|||Forms a heterodimer with MurT.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT. http://togogenome.org/gene/47853:HXZ27_RS23110 ^@ http://purl.uniprot.org/uniprot/A0A1C4Y523 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/47853:HXZ27_RS28350 ^@ http://purl.uniprot.org/uniprot/A0A1C4U7Q7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/47853:HXZ27_RS27560 ^@ http://purl.uniprot.org/uniprot/A0A1C4UFJ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/47853:HXZ27_RS09810 ^@ http://purl.uniprot.org/uniprot/A0A1C5AX62 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/47853:HXZ27_RS08545 ^@ http://purl.uniprot.org/uniprot/A0A1C4WF32 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/47853:HXZ27_RS27520 ^@ http://purl.uniprot.org/uniprot/A0A1C4UFZ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/47853:HXZ27_RS08150 ^@ http://purl.uniprot.org/uniprot/A0A7H8XKT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/47853:HXZ27_RS02070 ^@ http://purl.uniprot.org/uniprot/A0A1C4YXD7 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/47853:HXZ27_RS21975 ^@ http://purl.uniprot.org/uniprot/A0A1C4X920 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/47853:HXZ27_RS21720 ^@ http://purl.uniprot.org/uniprot/A0A1C4X6G8 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/47853:HXZ27_RS19380 ^@ http://purl.uniprot.org/uniprot/A0A1C4ZXB3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/47853:HXZ27_RS17435 ^@ http://purl.uniprot.org/uniprot/A0A1C4VTB1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/47853:HXZ27_RS07870 ^@ http://purl.uniprot.org/uniprot/A0A1C4W915 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/47853:HXZ27_RS14210 ^@ http://purl.uniprot.org/uniprot/A0A1C4ZSJ2 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/47853:HXZ27_RS10765 ^@ http://purl.uniprot.org/uniprot/A0A1C4ZDT7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/47853:HXZ27_RS07055 ^@ http://purl.uniprot.org/uniprot/A0A1C4W1R7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 12 (cellulase H) family. http://togogenome.org/gene/47853:HXZ27_RS04630 ^@ http://purl.uniprot.org/uniprot/A0A1C5AFW0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/47853:HXZ27_RS11680 ^@ http://purl.uniprot.org/uniprot/A0A1C4ZJ95 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.|||Cell membrane|||Contains a di-nuclear catalytic Mg(2+) center.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/47853:HXZ27_RS23815 ^@ http://purl.uniprot.org/uniprot/A0A1C4XWS5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/47853:HXZ27_RS08315 ^@ http://purl.uniprot.org/uniprot/A0A1C4WCL4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/47853:HXZ27_RS21835 ^@ http://purl.uniprot.org/uniprot/A0A1C4X8B3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS06420 ^@ http://purl.uniprot.org/uniprot/A0A1C5ARK2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the faeC family.|||Involved in degradation of plant cell walls. Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans, and the feruloyl-galactose ester bond in pectin. Active against paranitrophenyl-acetate, methyl ferulate and wheat arabinoxylan.|||Secreted http://togogenome.org/gene/47853:HXZ27_RS21090 ^@ http://purl.uniprot.org/uniprot/A0A1C4WVX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/47853:HXZ27_RS21815 ^@ http://purl.uniprot.org/uniprot/A0A1C4X7M0 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/47853:HXZ27_RS11775 ^@ http://purl.uniprot.org/uniprot/A0A1C4ZKF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/47853:HXZ27_RS27530 ^@ http://purl.uniprot.org/uniprot/A0A1C4UFR1 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/47853:HXZ27_RS31330 ^@ http://purl.uniprot.org/uniprot/A0A7H8XW90 ^@ Similarity|||Subunit ^@ Belongs to the Bpa family.|||Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings. http://togogenome.org/gene/47853:HXZ27_RS24670 ^@ http://purl.uniprot.org/uniprot/A0A1C4XMW9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/47853:HXZ27_RS20510 ^@ http://purl.uniprot.org/uniprot/A0A1C5ASR2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/47853:HXZ27_RS05075 ^@ http://purl.uniprot.org/uniprot/A0A7H8XF29 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/47853:HXZ27_RS17785 ^@ http://purl.uniprot.org/uniprot/A0A1C5AHL3 ^@ Similarity|||Subunit ^@ Belongs to the AAA ATPase family.|||Homohexamer. Assembles into a hexameric ring structure. http://togogenome.org/gene/47853:HXZ27_RS27660 ^@ http://purl.uniprot.org/uniprot/A0A1C4UEG0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/47853:HXZ27_RS19330 ^@ http://purl.uniprot.org/uniprot/A0A1C4ZXD3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/47853:HXZ27_RS22945 ^@ http://purl.uniprot.org/uniprot/A0A1C4Y6I2 ^@ Caution|||Cofactor|||Function|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/47853:HXZ27_RS24595 ^@ http://purl.uniprot.org/uniprot/A0A1C4XNP7 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/47853:HXZ27_RS16890 ^@ http://purl.uniprot.org/uniprot/A0A1C4VNW8 ^@ Similarity ^@ Belongs to the CsoR family. http://togogenome.org/gene/47853:HXZ27_RS25950 ^@ http://purl.uniprot.org/uniprot/A0A1C4UVX8 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/47853:HXZ27_RS08125 ^@ http://purl.uniprot.org/uniprot/A0A1C4WBW1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ A probable RNA-binding protein.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS22560 ^@ http://purl.uniprot.org/uniprot/A0A1C4XFH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS03265 ^@ http://purl.uniprot.org/uniprot/A0A1C4YL25 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/47853:HXZ27_RS13250 ^@ http://purl.uniprot.org/uniprot/A0A1C5APG7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS12955 ^@ http://purl.uniprot.org/uniprot/A0A1C5ANS6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 27 family. http://togogenome.org/gene/47853:HXZ27_RS24885 ^@ http://purl.uniprot.org/uniprot/A0A1C5AMG3 ^@ Caution|||Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/47853:HXZ27_RS05450 ^@ http://purl.uniprot.org/uniprot/A0A1C5A588 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS02795 ^@ http://purl.uniprot.org/uniprot/A0A1C4YNX0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS29040 ^@ http://purl.uniprot.org/uniprot/A0A1C4U149 ^@ Cofactor|||Similarity ^@ Belongs to the 4HPPD family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/47853:HXZ27_RS02480 ^@ http://purl.uniprot.org/uniprot/A0A1C4YSI2 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/47853:HXZ27_RS25130 ^@ http://purl.uniprot.org/uniprot/A0A1C5AM06 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/47853:HXZ27_RS29105 ^@ http://purl.uniprot.org/uniprot/A0A1C4U0P3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/47853:HXZ27_RS23820 ^@ http://purl.uniprot.org/uniprot/A0A1C4XWI5 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS10760 ^@ http://purl.uniprot.org/uniprot/A0A1C4ZDZ6 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/47853:HXZ27_RS08660 ^@ http://purl.uniprot.org/uniprot/A0A1C4WG13 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/47853:HXZ27_RS19505 ^@ http://purl.uniprot.org/uniprot/A0A1C4ZXT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sbp family.|||Cell membrane http://togogenome.org/gene/47853:HXZ27_RS08015 ^@ http://purl.uniprot.org/uniprot/A0A7H8XTQ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/47853:HXZ27_RS22670 ^@ http://purl.uniprot.org/uniprot/A0A1C4XGC5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/47853:HXZ27_RS07475 ^@ http://purl.uniprot.org/uniprot/A0A1C4W679 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/47853:HXZ27_RS10290 ^@ http://purl.uniprot.org/uniprot/A0A1C5AV73 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS22625 ^@ http://purl.uniprot.org/uniprot/A0A1C4XFC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DivIVA family.|||Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS22885 ^@ http://purl.uniprot.org/uniprot/A0A1C4Y742 ^@ Similarity ^@ Belongs to the class-II DAHP synthase family. http://togogenome.org/gene/47853:HXZ27_RS26145 ^@ http://purl.uniprot.org/uniprot/A0A1C4UU32 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/47853:HXZ27_RS08790 ^@ http://purl.uniprot.org/uniprot/A0A1C4WHE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/47853:HXZ27_RS00955 ^@ http://purl.uniprot.org/uniprot/A0A1C4Z3F6 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/47853:HXZ27_RS14295 ^@ http://purl.uniprot.org/uniprot/A0A7H8XL01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/47853:HXZ27_RS07140 ^@ http://purl.uniprot.org/uniprot/A0A1C4W2R0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS27610 ^@ http://purl.uniprot.org/uniprot/A0A1C4UF01 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/47853:HXZ27_RS26310 ^@ http://purl.uniprot.org/uniprot/A0A1C4USK4 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/47853:HXZ27_RS24445 ^@ http://purl.uniprot.org/uniprot/A0A1C4XQQ3 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/47853:HXZ27_RS28200 ^@ http://purl.uniprot.org/uniprot/A0A1C4U9E2 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/47853:HXZ27_RS08140 ^@ http://purl.uniprot.org/uniprot/A0A1C4WBW7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/47853:HXZ27_RS27655 ^@ http://purl.uniprot.org/uniprot/A0A1C4UEF3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/47853:HXZ27_RS26995 ^@ http://purl.uniprot.org/uniprot/A0A1C4UKW2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/47853:HXZ27_RS20365 ^@ http://purl.uniprot.org/uniprot/A0A1C5ASK7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/47853:HXZ27_RS00315 ^@ http://purl.uniprot.org/uniprot/A0A1C4Z7V6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS02005 ^@ http://purl.uniprot.org/uniprot/A0A1C4YXE8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/47853:HXZ27_RS29355 ^@ http://purl.uniprot.org/uniprot/A0A7H8XUZ2 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/47853:HXZ27_RS31740 ^@ http://purl.uniprot.org/uniprot/A0A7H8XT59 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/47853:HXZ27_RS26390 ^@ http://purl.uniprot.org/uniprot/A0A1C4URL7 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/47853:HXZ27_RS00720 ^@ http://purl.uniprot.org/uniprot/A0A1C4Z4V4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/47853:HXZ27_RS22845 ^@ http://purl.uniprot.org/uniprot/A0A1C4XHK6 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/47853:HXZ27_RS13205 ^@ http://purl.uniprot.org/uniprot/A0A1C5AP73 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/47853:HXZ27_RS17795 ^@ http://purl.uniprot.org/uniprot/A0A7D6CGN6 ^@ Caution|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic ubiquitin-like protein family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.|||Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.|||The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome. http://togogenome.org/gene/47853:HXZ27_RS17510 ^@ http://purl.uniprot.org/uniprot/A0A1C4VU65 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS27210 ^@ http://purl.uniprot.org/uniprot/A0A1C4UJ27 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/47853:HXZ27_RS29150 ^@ http://purl.uniprot.org/uniprot/A0A1C4U074 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/47853:HXZ27_RS05745 ^@ http://purl.uniprot.org/uniprot/A0A1C5A479 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/47853:HXZ27_RS07980 ^@ http://purl.uniprot.org/uniprot/A0A1C4WA47 ^@ Similarity ^@ Belongs to the helicase family. RecG subfamily. http://togogenome.org/gene/47853:HXZ27_RS07275 ^@ http://purl.uniprot.org/uniprot/A0A1C4W416 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS26690 ^@ http://purl.uniprot.org/uniprot/A0A1C4UNK9 ^@ Cofactor|||Function ^@ Binds 1 [3Fe-4S] cluster.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/47853:HXZ27_RS05230 ^@ http://purl.uniprot.org/uniprot/A0A7H8XG79 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/47853:HXZ27_RS00015 ^@ http://purl.uniprot.org/uniprot/A0A1C5AR26 ^@ Similarity ^@ Belongs to the 6-phosphogluconate dehydrogenase family. http://togogenome.org/gene/47853:HXZ27_RS09100 ^@ http://purl.uniprot.org/uniprot/A0A1C4WKB4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/47853:HXZ27_RS21930 ^@ http://purl.uniprot.org/uniprot/A0A1C4X8G6 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/47853:HXZ27_RS27360 ^@ http://purl.uniprot.org/uniprot/A0A1C4UHH4 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/47853:HXZ27_RS31270 ^@ http://purl.uniprot.org/uniprot/A0A1C5AQG1 ^@ Similarity ^@ Belongs to the arginine deiminase family. http://togogenome.org/gene/47853:HXZ27_RS02015 ^@ http://purl.uniprot.org/uniprot/A0A1C4YXS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/47853:HXZ27_RS04475 ^@ http://purl.uniprot.org/uniprot/A0A1C5AFI3 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/47853:HXZ27_RS27180 ^@ http://purl.uniprot.org/uniprot/A0A7D5YC03 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/47853:HXZ27_RS20525 ^@ http://purl.uniprot.org/uniprot/A0A1C5ASS2 ^@ Similarity ^@ Belongs to the OMP decarboxylase family. Type 2 subfamily. http://togogenome.org/gene/47853:HXZ27_RS10295 ^@ http://purl.uniprot.org/uniprot/A0A1C5AV46 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/47853:HXZ27_RS30835 ^@ http://purl.uniprot.org/uniprot/A0A1C5AVY7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS27680 ^@ http://purl.uniprot.org/uniprot/A0A1C4UE96 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/47853:HXZ27_RS24630 ^@ http://purl.uniprot.org/uniprot/A0A7H8XY79 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/47853:HXZ27_RS25760 ^@ http://purl.uniprot.org/uniprot/A0A1C5AKC0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NucS endonuclease family.|||Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.|||Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS23205 ^@ http://purl.uniprot.org/uniprot/A0A1C4Y514 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/47853:HXZ27_RS19060 ^@ http://purl.uniprot.org/uniprot/A0A1C4ZVW9 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/47853:HXZ27_RS29395 ^@ http://purl.uniprot.org/uniprot/A0A7D6CDT2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/47853:HXZ27_RS21365 ^@ http://purl.uniprot.org/uniprot/A0A1C4X3E9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/47853:HXZ27_RS27640 ^@ http://purl.uniprot.org/uniprot/A0A1C4UEN3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/47853:HXZ27_RS24655 ^@ http://purl.uniprot.org/uniprot/A0A1C4XN94 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/47853:HXZ27_RS29260 ^@ http://purl.uniprot.org/uniprot/A0A1C4TZL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/47853:HXZ27_RS07405 ^@ http://purl.uniprot.org/uniprot/A0A1C4W5D7 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/47853:HXZ27_RS00870 ^@ http://purl.uniprot.org/uniprot/A0A1C4Z3V7 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/47853:HXZ27_RS23400 ^@ http://purl.uniprot.org/uniprot/A0A1C4Y1R9 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/47853:HXZ27_RS27615 ^@ http://purl.uniprot.org/uniprot/A0A1C4UEU7 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/47853:HXZ27_RS15015 ^@ http://purl.uniprot.org/uniprot/A0A1C4ZN20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/47853:HXZ27_RS20775 ^@ http://purl.uniprot.org/uniprot/A0A1C5ATM2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/47853:HXZ27_RS21870 ^@ http://purl.uniprot.org/uniprot/A0A1C4X886 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/47853:HXZ27_RS27605 ^@ http://purl.uniprot.org/uniprot/A0A1C4UEZ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/47853:HXZ27_RS31555 ^@ http://purl.uniprot.org/uniprot/A0A1C5AR40 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/47853:HXZ27_RS10695 ^@ http://purl.uniprot.org/uniprot/A0A1C4ZD86 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/47853:HXZ27_RS20390 ^@ http://purl.uniprot.org/uniprot/A0A7D6C834 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS22245 ^@ http://purl.uniprot.org/uniprot/A0A7H8XQ26 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/47853:HXZ27_RS28410 ^@ http://purl.uniprot.org/uniprot/A0A1C4U782 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/47853:HXZ27_RS04685 ^@ http://purl.uniprot.org/uniprot/A0A1C5AG77 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/47853:HXZ27_RS14865 ^@ http://purl.uniprot.org/uniprot/A0A1C4ZP82 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/47853:HXZ27_RS21295 ^@ http://purl.uniprot.org/uniprot/A0A1C4X3F0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/47853:HXZ27_RS08160 ^@ http://purl.uniprot.org/uniprot/A0A1C4WCF8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/47853:HXZ27_RS09980 ^@ http://purl.uniprot.org/uniprot/A0A1C5AXF6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SsgA family.|||Cell septum http://togogenome.org/gene/47853:HXZ27_RS25435 ^@ http://purl.uniprot.org/uniprot/A0A1C5AL00 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/47853:HXZ27_RS27300 ^@ http://purl.uniprot.org/uniprot/A0A1C4UI48 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/47853:HXZ27_RS22645 ^@ http://purl.uniprot.org/uniprot/A0A7H8XP79 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/47853:HXZ27_RS08560 ^@ http://purl.uniprot.org/uniprot/A0A1C4WF53 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/47853:HXZ27_RS07265 ^@ http://purl.uniprot.org/uniprot/A0A1C4W3Q9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS19815 ^@ http://purl.uniprot.org/uniprot/A0A1C5A004 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase-binding protein RbpA family.|||Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.|||Forms a complex with the RNAP catalytic core and with free principal sigma factors.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/47853:HXZ27_RS08120 ^@ http://purl.uniprot.org/uniprot/A0A1C4WBT6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/47853:HXZ27_RS05725 ^@ http://purl.uniprot.org/uniprot/A0A1C5A4L6 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/47853:HXZ27_RS27235 ^@ http://purl.uniprot.org/uniprot/A0A7H8XYD0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein S18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS05030 ^@ http://purl.uniprot.org/uniprot/A0A1C5A6X0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/47853:HXZ27_RS17175 ^@ http://purl.uniprot.org/uniprot/A0A1C4VR58 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/47853:HXZ27_RS06480 ^@ http://purl.uniprot.org/uniprot/A0A7H8XJA6 ^@ Similarity ^@ Belongs to the PGI/PMI family. http://togogenome.org/gene/47853:HXZ27_RS18375 ^@ http://purl.uniprot.org/uniprot/A0A1C5AJ91 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/47853:HXZ27_RS13225 ^@ http://purl.uniprot.org/uniprot/A0A1C5ANT7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.|||Cytoplasm|||Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.|||Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/47853:HXZ27_RS27705 ^@ http://purl.uniprot.org/uniprot/A0A1C4UDZ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/47853:HXZ27_RS23210 ^@ http://purl.uniprot.org/uniprot/A0A1C4Y3Z7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/47853:HXZ27_RS05650 ^@ http://purl.uniprot.org/uniprot/A0A7H8XGE2 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/47853:HXZ27_RS07970 ^@ http://purl.uniprot.org/uniprot/A0A1C4WA42 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/47853:HXZ27_RS27285 ^@ http://purl.uniprot.org/uniprot/A0A1C4UIA4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/47853:HXZ27_RS25025 ^@ http://purl.uniprot.org/uniprot/A0A1C5ALT9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 3-HAO family.|||Binds 2 Fe(2+) ions per subunit.|||Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. http://togogenome.org/gene/47853:HXZ27_RS07505 ^@ http://purl.uniprot.org/uniprot/A0A7D5Y6T2 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/47853:HXZ27_RS28590 ^@ http://purl.uniprot.org/uniprot/A0A1C4U504 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/47853:HXZ27_RS27630 ^@ http://purl.uniprot.org/uniprot/A0A1C4UET2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/47853:HXZ27_RS00375 ^@ http://purl.uniprot.org/uniprot/A0A1C4Z7F7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS28620 ^@ http://purl.uniprot.org/uniprot/A0A1C4U4J6 ^@ Similarity ^@ Belongs to the PhoU family.|||Belongs to the UPF0111 family. http://togogenome.org/gene/47853:HXZ27_RS05085 ^@ http://purl.uniprot.org/uniprot/A0A1C5A6W2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/47853:HXZ27_RS29190 ^@ http://purl.uniprot.org/uniprot/A0A1C4U025 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/47853:HXZ27_RS21405 ^@ http://purl.uniprot.org/uniprot/A0A1C4X4E6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/47853:HXZ27_RS21360 ^@ http://purl.uniprot.org/uniprot/A0A1C4X394 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/47853:HXZ27_RS18415 ^@ http://purl.uniprot.org/uniprot/A0A1C5AJ96 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS27540 ^@ http://purl.uniprot.org/uniprot/A0A1C4UFL3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/47853:HXZ27_RS07100 ^@ http://purl.uniprot.org/uniprot/A0A7H8XJL6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/47853:HXZ27_RS01960 ^@ http://purl.uniprot.org/uniprot/A0A1C4YXZ4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/47853:HXZ27_RS22630 ^@ http://purl.uniprot.org/uniprot/A0A1C4XFG7 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/47853:HXZ27_RS31485 ^@ http://purl.uniprot.org/uniprot/A0A1C5AR66 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS04430 ^@ http://purl.uniprot.org/uniprot/A0A1C5AFX4 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/47853:HXZ27_RS22600 ^@ http://purl.uniprot.org/uniprot/A0A1C4XFM5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/47853:HXZ27_RS08325 ^@ http://purl.uniprot.org/uniprot/A0A1C4WCS7 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/47853:HXZ27_RS04205 ^@ http://purl.uniprot.org/uniprot/A0A1C5AEI7 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/47853:HXZ27_RS08130 ^@ http://purl.uniprot.org/uniprot/A0A1C4WC50 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/47853:HXZ27_RS27720 ^@ http://purl.uniprot.org/uniprot/A0A1C4UDV1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/47853:HXZ27_RS08440 ^@ http://purl.uniprot.org/uniprot/A0A1C4WDZ6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/47853:HXZ27_RS25475 ^@ http://purl.uniprot.org/uniprot/A0A1C5AKX0 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/47853:HXZ27_RS06475 ^@ http://purl.uniprot.org/uniprot/A0A1C5ARZ3 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/47853:HXZ27_RS29755 ^@ http://purl.uniprot.org/uniprot/A0A1C4TWC3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/47853:HXZ27_RS05720 ^@ http://purl.uniprot.org/uniprot/A0A1C5A4H6 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/47853:HXZ27_RS24515 ^@ http://purl.uniprot.org/uniprot/A0A1C4XPS8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS22860 ^@ http://purl.uniprot.org/uniprot/A0A1C4Y7B3 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/47853:HXZ27_RS08010 ^@ http://purl.uniprot.org/uniprot/A0A1C4WAC8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/47853:HXZ27_RS21970 ^@ http://purl.uniprot.org/uniprot/A0A1C4X8X1 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/47853:HXZ27_RS06320 ^@ http://purl.uniprot.org/uniprot/A0A1C5ARH2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS10540 ^@ http://purl.uniprot.org/uniprot/A0A1C4ZC48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/47853:HXZ27_RS22700 ^@ http://purl.uniprot.org/uniprot/A0A1C4XGD7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/47853:HXZ27_RS09005 ^@ http://purl.uniprot.org/uniprot/A0A1C4WJH4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase Y family.|||Cell membrane|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/47853:HXZ27_RS13590 ^@ http://purl.uniprot.org/uniprot/A0A1C5AWI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/47853:HXZ27_RS27710 ^@ http://purl.uniprot.org/uniprot/A0A1C4UDW8 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/47853:HXZ27_RS28615 ^@ http://purl.uniprot.org/uniprot/A0A1C4U4R0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS04170 ^@ http://purl.uniprot.org/uniprot/A0A1C5AEE0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/47853:HXZ27_RS11610 ^@ http://purl.uniprot.org/uniprot/A0A1C4ZJ99 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS19515 ^@ http://purl.uniprot.org/uniprot/A0A1C4ZXX9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/47853:HXZ27_RS07940 ^@ http://purl.uniprot.org/uniprot/A0A1C4W9R3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS01775 ^@ http://purl.uniprot.org/uniprot/A0A1C4YZC2 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/47853:HXZ27_RS27735 ^@ http://purl.uniprot.org/uniprot/A0A1C4UDP9 ^@ Similarity ^@ Belongs to the UPF0336 family. http://togogenome.org/gene/47853:HXZ27_RS22935 ^@ http://purl.uniprot.org/uniprot/A0A7H8XWI6 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Non-allosteric. http://togogenome.org/gene/47853:HXZ27_RS31680 ^@ http://purl.uniprot.org/uniprot/A0A1C5AQX5 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/47853:HXZ27_RS21960 ^@ http://purl.uniprot.org/uniprot/A0A1C4X8Q6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/47853:HXZ27_RS24560 ^@ http://purl.uniprot.org/uniprot/A0A1C4XQA1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/47853:HXZ27_RS26595 ^@ http://purl.uniprot.org/uniprot/A0A1C4UPL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/47853:HXZ27_RS04975 ^@ http://purl.uniprot.org/uniprot/A0A1C5A779 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/47853:HXZ27_RS03055 ^@ http://purl.uniprot.org/uniprot/A0A1C4YM47 ^@ Similarity ^@ Belongs to the CsoR family. http://togogenome.org/gene/47853:HXZ27_RS21965 ^@ http://purl.uniprot.org/uniprot/A0A1C4X8T8 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/47853:HXZ27_RS22055 ^@ http://purl.uniprot.org/uniprot/A0A1C4X9N1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/47853:HXZ27_RS04200 ^@ http://purl.uniprot.org/uniprot/A0A1C5AEK4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/47853:HXZ27_RS00035 ^@ http://purl.uniprot.org/uniprot/A0A1C5AR08 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/47853:HXZ27_RS27230 ^@ http://purl.uniprot.org/uniprot/A0A1C4UIS1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/47853:HXZ27_RS27740 ^@ http://purl.uniprot.org/uniprot/A0A1C4UDN0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/47853:HXZ27_RS05560 ^@ http://purl.uniprot.org/uniprot/A0A1C5A516 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.|||Belongs to the MshB deacetylase family. Mca subfamily.|||Binds 1 zinc ion per subunit.|||Monomer. http://togogenome.org/gene/47853:HXZ27_RS11155 ^@ http://purl.uniprot.org/uniprot/A0A7H8XJ88 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/47853:HXZ27_RS27505 ^@ http://purl.uniprot.org/uniprot/A0A1C4UG21 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/47853:HXZ27_RS25470 ^@ http://purl.uniprot.org/uniprot/A0A1C5AKW6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/47853:HXZ27_RS07730 ^@ http://purl.uniprot.org/uniprot/A0A1C4W7W1 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/47853:HXZ27_RS25915 ^@ http://purl.uniprot.org/uniprot/A0A1C4UWG3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/47853:HXZ27_RS21950 ^@ http://purl.uniprot.org/uniprot/A0A1C4X8P2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Membrane http://togogenome.org/gene/47853:HXZ27_RS02450 ^@ http://purl.uniprot.org/uniprot/A0A1C4YRK0 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/47853:HXZ27_RS08595 ^@ http://purl.uniprot.org/uniprot/A0A1C4WGA1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/47853:HXZ27_RS29110 ^@ http://purl.uniprot.org/uniprot/A0A1C4U0E7 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/47853:HXZ27_RS30885 ^@ http://purl.uniprot.org/uniprot/A0A7H8XVC8 ^@ Subcellular Location Annotation ^@ Membrane|||Nucleus membrane http://togogenome.org/gene/47853:HXZ27_RS09260 ^@ http://purl.uniprot.org/uniprot/A0A1C4WM30 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/47853:HXZ27_RS25855 ^@ http://purl.uniprot.org/uniprot/A0A7H8XTV3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/47853:HXZ27_RS27595 ^@ http://purl.uniprot.org/uniprot/A0A7D6CDD8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/47853:HXZ27_RS27585 ^@ http://purl.uniprot.org/uniprot/A0A1C4UF45 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/47853:HXZ27_RS24405 ^@ http://purl.uniprot.org/uniprot/A0A1C4XS22 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of glycine to tRNA(Gly).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/47853:HXZ27_RS27485 ^@ http://purl.uniprot.org/uniprot/A0A1C4UG85 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/47853:HXZ27_RS06600 ^@ http://purl.uniprot.org/uniprot/A0A1C5AS08 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/47853:HXZ27_RS29435 ^@ http://purl.uniprot.org/uniprot/A0A1C4TY87 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/47853:HXZ27_RS25955 ^@ http://purl.uniprot.org/uniprot/A0A7H8XVY8 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/47853:HXZ27_RS22900 ^@ http://purl.uniprot.org/uniprot/A0A1C4Y702 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/47853:HXZ27_RS29740 ^@ http://purl.uniprot.org/uniprot/A0A7H8XS98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/47853:HXZ27_RS09665 ^@ http://purl.uniprot.org/uniprot/A0A1C5AWY3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/47853:HXZ27_RS27620 ^@ http://purl.uniprot.org/uniprot/A0A7H8XS19 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/47853:HXZ27_RS21485 ^@ http://purl.uniprot.org/uniprot/A0A1C4X4K7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurD2 subfamily.|||Cell wall formation. Catalyzes the addition of L-glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine.|||Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS23035 ^@ http://purl.uniprot.org/uniprot/A0A1C4Y5Q0 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/47853:HXZ27_RS27495 ^@ http://purl.uniprot.org/uniprot/A0A1C4UG19 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/47853:HXZ27_RS30065 ^@ http://purl.uniprot.org/uniprot/A0A1C4Y8K8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/47853:HXZ27_RS27645 ^@ http://purl.uniprot.org/uniprot/A0A1C4UEK2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/47853:HXZ27_RS02630 ^@ http://purl.uniprot.org/uniprot/A0A1C4YQK1 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/47853:HXZ27_RS08340 ^@ http://purl.uniprot.org/uniprot/A0A1C4WCY3 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/47853:HXZ27_RS16415 ^@ http://purl.uniprot.org/uniprot/A0A1C4VID2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/47853:HXZ27_RS03590 ^@ http://purl.uniprot.org/uniprot/A0A1C4YJ09 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS07910 ^@ http://purl.uniprot.org/uniprot/A0A1C4W9E9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS23765 ^@ http://purl.uniprot.org/uniprot/A0A1C4XX66 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS26800 ^@ http://purl.uniprot.org/uniprot/A0A1C4UMD8 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/47853:HXZ27_RS21940 ^@ http://purl.uniprot.org/uniprot/A0A1C4X8X7 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/47853:HXZ27_RS26960 ^@ http://purl.uniprot.org/uniprot/A0A1C4UL41 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/47853:HXZ27_RS19890 ^@ http://purl.uniprot.org/uniprot/A0A7H8XR27 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/47853:HXZ27_RS06535 ^@ http://purl.uniprot.org/uniprot/A0A7H8XFU9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/47853:HXZ27_RS00010 ^@ http://purl.uniprot.org/uniprot/A0A1C5AQW8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/47853:HXZ27_RS07430 ^@ http://purl.uniprot.org/uniprot/A0A1C4W5Z2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS21955 ^@ http://purl.uniprot.org/uniprot/A0A1C4X8Q7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/47853:HXZ27_RS25795 ^@ http://purl.uniprot.org/uniprot/A0A1C4UXS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/47853:HXZ27_RS10570 ^@ http://purl.uniprot.org/uniprot/A0A1C4ZCJ1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/47853:HXZ27_RS28405 ^@ http://purl.uniprot.org/uniprot/A0A1C4U7A4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/47853:HXZ27_RS20485 ^@ http://purl.uniprot.org/uniprot/A0A1C5AT88 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/47853:HXZ27_RS18700 ^@ http://purl.uniprot.org/uniprot/A0A1C5AYW3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/47853:HXZ27_RS27685 ^@ http://purl.uniprot.org/uniprot/A0A1C4UE86 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/47853:HXZ27_RS21560 ^@ http://purl.uniprot.org/uniprot/A0A1C4X586 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. http://togogenome.org/gene/47853:HXZ27_RS29420 ^@ http://purl.uniprot.org/uniprot/A0A7H8XS51 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS00620 ^@ http://purl.uniprot.org/uniprot/A0A1C4Z5V3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0719 family.|||Membrane http://togogenome.org/gene/47853:HXZ27_RS01680 ^@ http://purl.uniprot.org/uniprot/A0A7H8XDP0 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/47853:HXZ27_RS00845 ^@ http://purl.uniprot.org/uniprot/A0A1C4Z469 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/47853:HXZ27_RS28840 ^@ http://purl.uniprot.org/uniprot/A0A1C4U2K1 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/47853:HXZ27_RS16030 ^@ http://purl.uniprot.org/uniprot/A0A1C4VF06 ^@ Similarity ^@ Belongs to the WrbA family. http://togogenome.org/gene/47853:HXZ27_RS27805 ^@ http://purl.uniprot.org/uniprot/A0A1C4UD06 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/47853:HXZ27_RS07775 ^@ http://purl.uniprot.org/uniprot/A0A1C4W886 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS17220 ^@ http://purl.uniprot.org/uniprot/A0A1C4VRY3 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/47853:HXZ27_RS27565 ^@ http://purl.uniprot.org/uniprot/A0A1C4UFD7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/47853:HXZ27_RS12155 ^@ http://purl.uniprot.org/uniprot/A0A1C5ATN4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/47853:HXZ27_RS23945 ^@ http://purl.uniprot.org/uniprot/A0A1C4XVA0 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/47853:HXZ27_RS06595 ^@ http://purl.uniprot.org/uniprot/A0A1C5ARY0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/47853:HXZ27_RS04470 ^@ http://purl.uniprot.org/uniprot/A0A1C5AFF6 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/47853:HXZ27_RS23340 ^@ http://purl.uniprot.org/uniprot/A0A1C4Y2F0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons. http://togogenome.org/gene/47853:HXZ27_RS15780 ^@ http://purl.uniprot.org/uniprot/A0A1C4VCC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/47853:HXZ27_RS27635 ^@ http://purl.uniprot.org/uniprot/A0A1C4UEK3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/47853:HXZ27_RS22635 ^@ http://purl.uniprot.org/uniprot/A0A1C4XFP0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/47853:HXZ27_RS20480 ^@ http://purl.uniprot.org/uniprot/A0A1C5AT48 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/47853:HXZ27_RS25815 ^@ http://purl.uniprot.org/uniprot/A0A7H8XQ89 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/47853:HXZ27_RS04745 ^@ http://purl.uniprot.org/uniprot/A0A1C5A879 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/47853:HXZ27_RS27545 ^@ http://purl.uniprot.org/uniprot/A0A1C4UFJ2 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/47853:HXZ27_RS02465 ^@ http://purl.uniprot.org/uniprot/A0A7H8XF37 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/47853:HXZ27_RS00695 ^@ http://purl.uniprot.org/uniprot/A0A1C4Z565 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/47853:HXZ27_RS31745 ^@ http://purl.uniprot.org/uniprot/A0A7H8XUU6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/47853:HXZ27_RS24890 ^@ http://purl.uniprot.org/uniprot/A0A1C5AN22 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/47853:HXZ27_RS00840 ^@ http://purl.uniprot.org/uniprot/A0A1C4Z3Z6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/47853:HXZ27_RS24265 ^@ http://purl.uniprot.org/uniprot/A0A1C4XSN7 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/47853:HXZ27_RS31750 ^@ http://purl.uniprot.org/uniprot/A0A1C5AQY6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/47853:HXZ27_RS21535 ^@ http://purl.uniprot.org/uniprot/A0A1C4X502 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/47853:HXZ27_RS27510 ^@ http://purl.uniprot.org/uniprot/A0A1C4UFX8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/47853:HXZ27_RS27570 ^@ http://purl.uniprot.org/uniprot/A0A1C4UFD4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/47853:HXZ27_RS17240 ^@ http://purl.uniprot.org/uniprot/A0A1C4VRQ1 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/47853:HXZ27_RS22970 ^@ http://purl.uniprot.org/uniprot/A0A1C4Y788 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/47853:HXZ27_RS04725 ^@ http://purl.uniprot.org/uniprot/A0A1C5A8H5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/47853:HXZ27_RS20760 ^@ http://purl.uniprot.org/uniprot/A0A7H8XNQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/47853:HXZ27_RS02075 ^@ http://purl.uniprot.org/uniprot/A0A1C4YX70 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/47853:HXZ27_RS27690 ^@ http://purl.uniprot.org/uniprot/A0A1C4UE49 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/47853:HXZ27_RS31645 ^@ http://purl.uniprot.org/uniprot/A0A1C5AQQ8 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. Flotillin subfamily. http://togogenome.org/gene/47853:HXZ27_RS29750 ^@ http://purl.uniprot.org/uniprot/A0A1C4TWC7 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/47853:HXZ27_RS27250 ^@ http://purl.uniprot.org/uniprot/A0A1C4UIJ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/47853:HXZ27_RS26525 ^@ http://purl.uniprot.org/uniprot/A0A1C4UQG9 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/47853:HXZ27_RS27515 ^@ http://purl.uniprot.org/uniprot/A0A1C4UFW3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/47853:HXZ27_RS05140 ^@ http://purl.uniprot.org/uniprot/A0A1C5A706 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/47853:HXZ27_RS24770 ^@ http://purl.uniprot.org/uniprot/A0A1C4XML5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/47853:HXZ27_RS31685 ^@ http://purl.uniprot.org/uniprot/A0A1C5AQV5 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/47853:HXZ27_RS28585 ^@ http://purl.uniprot.org/uniprot/A0A1C4U530 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PstS family.|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/47853:HXZ27_RS13710 ^@ http://purl.uniprot.org/uniprot/A0A1C5AWM1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS04100 ^@ http://purl.uniprot.org/uniprot/A0A7H8XTI0 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/47853:HXZ27_RS22595 ^@ http://purl.uniprot.org/uniprot/A0A1C4XFA9 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/47853:HXZ27_RS25865 ^@ http://purl.uniprot.org/uniprot/A0A7D6CEV4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/47853:HXZ27_RS04875 ^@ http://purl.uniprot.org/uniprot/A0A1C5A7P5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/47853:HXZ27_RS07070 ^@ http://purl.uniprot.org/uniprot/A0A1C4W1W7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/47853:HXZ27_RS11140 ^@ http://purl.uniprot.org/uniprot/A0A1C4ZGQ2 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/47853:HXZ27_RS31565 ^@ http://purl.uniprot.org/uniprot/A0A1C5AQM6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/47853:HXZ27_RS13795 ^@ http://purl.uniprot.org/uniprot/A0A1C5AWQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/47853:HXZ27_RS06250 ^@ http://purl.uniprot.org/uniprot/A0A1C5ARA6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/47853:HXZ27_RS09030 ^@ http://purl.uniprot.org/uniprot/A0A7H8XHT5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the selenophosphate synthase 1 family. Class I subfamily.|||Binds 1 Mg(2+) ion per monomer.|||Homodimer.|||Synthesizes selenophosphate from selenide and ATP. http://togogenome.org/gene/47853:HXZ27_RS00550 ^@ http://purl.uniprot.org/uniprot/A0A1C4Z606 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/47853:HXZ27_RS12755 ^@ http://purl.uniprot.org/uniprot/A0A1C5AV03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/47853:HXZ27_RS25710 ^@ http://purl.uniprot.org/uniprot/A0A7H8XR06 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/47853:HXZ27_RS06630 ^@ http://purl.uniprot.org/uniprot/A0A1C5ARV2 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/47853:HXZ27_RS03075 ^@ http://purl.uniprot.org/uniprot/A0A1C4YLW2 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/47853:HXZ27_RS27555 ^@ http://purl.uniprot.org/uniprot/A0A1C4UFF0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/47853:HXZ27_RS24710 ^@ http://purl.uniprot.org/uniprot/A0A7H8XQC8 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/47853:HXZ27_RS04275 ^@ http://purl.uniprot.org/uniprot/A0A1C5AET4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer.|||In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.|||In the N-terminal section; belongs to the MIP18 family. http://togogenome.org/gene/47853:HXZ27_RS23085 ^@ http://purl.uniprot.org/uniprot/A0A1C4Y572 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rieske iron-sulfur protein family.|||Cell membrane|||Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.|||Membrane http://togogenome.org/gene/47853:HXZ27_RS06590 ^@ http://purl.uniprot.org/uniprot/A0A7H8XGV2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/47853:HXZ27_RS25165 ^@ http://purl.uniprot.org/uniprot/A0A1C5ALH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF1 family.|||Cell membrane http://togogenome.org/gene/47853:HXZ27_RS27305 ^@ http://purl.uniprot.org/uniprot/A0A1C4UI52 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/47853:HXZ27_RS26955 ^@ http://purl.uniprot.org/uniprot/A0A1C4UL18 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. http://togogenome.org/gene/47853:HXZ27_RS26940 ^@ http://purl.uniprot.org/uniprot/A0A1C4ULB0 ^@ Cofactor|||Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/47853:HXZ27_RS28355 ^@ http://purl.uniprot.org/uniprot/A0A1C4U7N5 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/47853:HXZ27_RS29195 ^@ http://purl.uniprot.org/uniprot/A0A1C4TZU3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/47853:HXZ27_RS11930 ^@ http://purl.uniprot.org/uniprot/A0A1C5ATS5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 10 (cellulase F) family. http://togogenome.org/gene/47853:HXZ27_RS20765 ^@ http://purl.uniprot.org/uniprot/A0A7H8XRF2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/47853:HXZ27_RS22080 ^@ http://purl.uniprot.org/uniprot/A0A1C4XAL5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS08750 ^@ http://purl.uniprot.org/uniprot/A0A1C4WGV4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/47853:HXZ27_RS29365 ^@ http://purl.uniprot.org/uniprot/A0A1C4TYW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS00355 ^@ http://purl.uniprot.org/uniprot/A0A1C4Z7H6 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/47853:HXZ27_RS20575 ^@ http://purl.uniprot.org/uniprot/A0A1C5ASX4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/47853:HXZ27_RS26615 ^@ http://purl.uniprot.org/uniprot/A0A1C4UPF8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS31550 ^@ http://purl.uniprot.org/uniprot/A0A1C5AQN0 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/47853:HXZ27_RS31570 ^@ http://purl.uniprot.org/uniprot/A0A1C5AQN9 ^@ Similarity ^@ Belongs to the AP endonuclease 2 family. http://togogenome.org/gene/47853:HXZ27_RS28215 ^@ http://purl.uniprot.org/uniprot/A0A1C4U905 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/47853:HXZ27_RS20535 ^@ http://purl.uniprot.org/uniprot/A0A1C5AT00 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/47853:HXZ27_RS15990 ^@ http://purl.uniprot.org/uniprot/A0A1C4VE62 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/47853:HXZ27_RS04365 ^@ http://purl.uniprot.org/uniprot/A0A1C5AFJ7 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/47853:HXZ27_RS00390 ^@ http://purl.uniprot.org/uniprot/A0A1C4Z7W5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/47853:HXZ27_RS27600 ^@ http://purl.uniprot.org/uniprot/A0A1C4UEZ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/47853:HXZ27_RS20500 ^@ http://purl.uniprot.org/uniprot/A0A1C5ASX9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/47853:HXZ27_RS04850 ^@ http://purl.uniprot.org/uniprot/A0A7H8XJA5 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/47853:HXZ27_RS23095 ^@ http://purl.uniprot.org/uniprot/A0A7H8XSI6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/47853:HXZ27_RS07735 ^@ http://purl.uniprot.org/uniprot/A0A1C4W7U5 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/47853:HXZ27_RS27140 ^@ http://purl.uniprot.org/uniprot/A0A1C4UJK6 ^@ Similarity ^@ Belongs to the IMPDH/GMPR family. http://togogenome.org/gene/47853:HXZ27_RS28720 ^@ http://purl.uniprot.org/uniprot/A0A1C4U3M4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS04770 ^@ http://purl.uniprot.org/uniprot/A0A1C5A856 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/47853:HXZ27_RS08995 ^@ http://purl.uniprot.org/uniprot/A0A1C4WK55 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS27715 ^@ http://purl.uniprot.org/uniprot/A0A7H8XTI1 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/47853:HXZ27_RS17370 ^@ http://purl.uniprot.org/uniprot/A0A1C4VSP9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/47853:HXZ27_RS24980 ^@ http://purl.uniprot.org/uniprot/A0A1C5AM05 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/47853:HXZ27_RS06510 ^@ http://purl.uniprot.org/uniprot/A0A1C5ARQ1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the DyP-type peroxidase family.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.|||Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact. http://togogenome.org/gene/47853:HXZ27_RS31735 ^@ http://purl.uniprot.org/uniprot/A0A1C5AQW9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/47853:HXZ27_RS02995 ^@ http://purl.uniprot.org/uniprot/A0A1C4YNN8 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/47853:HXZ27_RS22200 ^@ http://purl.uniprot.org/uniprot/A0A1C4XBC9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS27550 ^@ http://purl.uniprot.org/uniprot/A0A1C4UFJ9 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/47853:HXZ27_RS07385 ^@ http://purl.uniprot.org/uniprot/A0A1C4W524 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/47853:HXZ27_RS08940 ^@ http://purl.uniprot.org/uniprot/A0A1C4WIU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/47853:HXZ27_RS23395 ^@ http://purl.uniprot.org/uniprot/A0A1C4Y2U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0719 family.|||Membrane http://togogenome.org/gene/47853:HXZ27_RS31510 ^@ http://purl.uniprot.org/uniprot/A0A1C5AQL2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/47853:HXZ27_RS23120 ^@ http://purl.uniprot.org/uniprot/A0A1C4Y4T7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with subunits I, II and III to form cytochrome c oxidase.|||Belongs to the cytochrome c oxidase bacterial subunit CtaF family.|||Cell membrane|||Membrane|||Part of cytochrome c oxidase, its function is unknown. http://togogenome.org/gene/47853:HXZ27_RS08330 ^@ http://purl.uniprot.org/uniprot/A0A1C4WCT8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/47853:HXZ27_RS21570 ^@ http://purl.uniprot.org/uniprot/A0A1C4X555 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/47853:HXZ27_RS24895 ^@ http://purl.uniprot.org/uniprot/A0A1C5AMF5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/47853:HXZ27_RS09095 ^@ http://purl.uniprot.org/uniprot/A0A1C4WK86 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/47853:HXZ27_RS17815 ^@ http://purl.uniprot.org/uniprot/A0A1C5AHK3 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.|||Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.|||The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group. http://togogenome.org/gene/47853:HXZ27_RS27940 ^@ http://purl.uniprot.org/uniprot/A0A1C4UBQ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS04800 ^@ http://purl.uniprot.org/uniprot/A0A7H8XIJ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS06620 ^@ http://purl.uniprot.org/uniprot/A0A1C5ARV9 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.|||Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Homohexamer. Dimer of a homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Purine nucleoside phosphorylase involved in purine salvage. http://togogenome.org/gene/47853:HXZ27_RS20430 ^@ http://purl.uniprot.org/uniprot/A0A1C5ASP0 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/47853:HXZ27_RS07995 ^@ http://purl.uniprot.org/uniprot/A0A1C4WA97 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/47853:HXZ27_RS16440 ^@ http://purl.uniprot.org/uniprot/A0A1C4VIQ8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/47853:HXZ27_RS01995 ^@ http://purl.uniprot.org/uniprot/A0A1C4YXX3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/47853:HXZ27_RS25925 ^@ http://purl.uniprot.org/uniprot/A0A7H8XQZ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS25530 ^@ http://purl.uniprot.org/uniprot/A0A1C5AL26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/47853:HXZ27_RS02020 ^@ http://purl.uniprot.org/uniprot/A0A1C4YXF5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/47853:HXZ27_RS01825 ^@ http://purl.uniprot.org/uniprot/A0A1C4YYV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Membrane http://togogenome.org/gene/47853:HXZ27_RS00215 ^@ http://purl.uniprot.org/uniprot/A0A1C4Z8G6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/47853:HXZ27_RS20360 ^@ http://purl.uniprot.org/uniprot/A0A1C5ASI6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/47853:HXZ27_RS13715 ^@ http://purl.uniprot.org/uniprot/A0A1C5AWL5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/47853:HXZ27_RS26860 ^@ http://purl.uniprot.org/uniprot/A0A1C4ULT6 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/47853:HXZ27_RS27625 ^@ http://purl.uniprot.org/uniprot/A0A1C4UET6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/47853:HXZ27_RS08075 ^@ http://purl.uniprot.org/uniprot/A0A1C4WC41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/47853:HXZ27_RS25840 ^@ http://purl.uniprot.org/uniprot/A0A1C4UX15 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/47853:HXZ27_RS29605 ^@ http://purl.uniprot.org/uniprot/A0A1C4TXE1 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/47853:HXZ27_RS00875 ^@ http://purl.uniprot.org/uniprot/A0A1C4Z3Z9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS27535 ^@ http://purl.uniprot.org/uniprot/A0A1C4UFP3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/47853:HXZ27_RS09885 ^@ http://purl.uniprot.org/uniprot/A0A1C5AXF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/47853:HXZ27_RS20290 ^@ http://purl.uniprot.org/uniprot/A0A7H8XXJ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/47853:HXZ27_RS12905 ^@ http://purl.uniprot.org/uniprot/A0A1C5AN33 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/47853:HXZ27_RS08980 ^@ http://purl.uniprot.org/uniprot/A0A1C4WJ85 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/47853:HXZ27_RS10095 ^@ http://purl.uniprot.org/uniprot/A0A1C5AVH7 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/47853:HXZ27_RS01980 ^@ http://purl.uniprot.org/uniprot/A0A1C4YY12 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/47853:HXZ27_RS14755 ^@ http://purl.uniprot.org/uniprot/A0A1C4ZPC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/47853:HXZ27_RS01965 ^@ http://purl.uniprot.org/uniprot/A0A1C4YXU0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 30 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/47853:HXZ27_RS25695 ^@ http://purl.uniprot.org/uniprot/A0A1C5AKD2 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/47853:HXZ27_RS17605 ^@ http://purl.uniprot.org/uniprot/A0A1C4VV28 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/47853:HXZ27_RS27500 ^@ http://purl.uniprot.org/uniprot/A0A7H8XR53 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy.