http://togogenome.org/gene/2546350:E1B03_RS17130 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS17750 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS07270 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2546350:E1B03_RS19550 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTQ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/2546350:E1B03_RS02350 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJY8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/2546350:E1B03_RS16085 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPX1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/2546350:E1B03_RS05880 ^@ http://purl.uniprot.org/uniprot/A0A4P6WK14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/2546350:E1B03_RS08300 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9Y2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS18530 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMG9 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2546350:E1B03_RS22265 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPK3 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family. HybF subfamily.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/2546350:E1B03_RS05690 ^@ http://purl.uniprot.org/uniprot/A0A4P6WGT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliQ/MopD/SpaQ family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS08280 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKA4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS19625 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQT1 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/2546350:E1B03_RS01170 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJ92 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS09475 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLR0 ^@ Subunit ^@ Monomer. http://togogenome.org/gene/2546350:E1B03_RS25225 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQW1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS18335 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTG2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2546350:E1B03_RS17955 ^@ http://purl.uniprot.org/uniprot/A0A4P6WM93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbE subfamily.|||Cell inner membrane http://togogenome.org/gene/2546350:E1B03_RS04775 ^@ http://purl.uniprot.org/uniprot/A0A4P6WGJ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.|||Cell inner membrane|||Homodimer. Interacts with KefC.|||Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC. http://togogenome.org/gene/2546350:E1B03_RS09250 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS17965 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQ11 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmE/CycJ family.|||Cell membrane|||Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. http://togogenome.org/gene/2546350:E1B03_RS01755 ^@ http://purl.uniprot.org/uniprot/A0A4P6WEZ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS21110 ^@ http://purl.uniprot.org/uniprot/A0A4P6WP30 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/2546350:E1B03_RS26130 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQ54 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/2546350:E1B03_RS05490 ^@ http://purl.uniprot.org/uniprot/A0A4P6WGV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2546350:E1B03_RS24355 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTP9 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/2546350:E1B03_RS19890 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNL4 ^@ Function ^@ Acts as a radical domain for damaged PFL and possibly other radical proteins. http://togogenome.org/gene/2546350:E1B03_RS17290 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSN4 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/2546350:E1B03_RS17915 ^@ http://purl.uniprot.org/uniprot/A0A4P6WT91 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/2546350:E1B03_RS11905 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLV1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/2546350:E1B03_RS24220 ^@ http://purl.uniprot.org/uniprot/A0A4P6WP41 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/2546350:E1B03_RS03680 ^@ http://purl.uniprot.org/uniprot/A0A4P6WF30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TamA family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS09585 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIN0 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/2546350:E1B03_RS05820 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/2546350:E1B03_RS18370 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQX8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2546350:E1B03_RS10400 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0312 family. Type 1 subfamily.|||Periplasm http://togogenome.org/gene/2546350:E1B03_RS24130 ^@ http://purl.uniprot.org/uniprot/A0A4P6WW13 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/2546350:E1B03_RS25705 ^@ http://purl.uniprot.org/uniprot/A0A4P6WWV0 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/2546350:E1B03_RS05445 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJU3 ^@ Similarity ^@ Belongs to the UPF0253 family. http://togogenome.org/gene/2546350:E1B03_RS21345 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSE2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.|||Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.|||Cytoplasm|||Monomer. http://togogenome.org/gene/2546350:E1B03_RS03230 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLF8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/2546350:E1B03_RS16040 ^@ http://purl.uniprot.org/uniprot/A0A4P6WP38 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.|||Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).|||Homodimer. http://togogenome.org/gene/2546350:E1B03_RS24080 ^@ http://purl.uniprot.org/uniprot/A0A4P6WVZ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/2546350:E1B03_RS04265 ^@ http://purl.uniprot.org/uniprot/A0A4P6WFB2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS24145 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQ07 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||Methylated by PrmB.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/2546350:E1B03_RS20070 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRY4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2546350:E1B03_RS08715 ^@ http://purl.uniprot.org/uniprot/A0A4P6WK65 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/2546350:E1B03_RS21935 ^@ http://purl.uniprot.org/uniprot/A0A4P6WV59 ^@ Function|||Similarity ^@ Belongs to the arginase family. Agmatinase subfamily.|||Catalyzes the formation of putrescine from agmatine. http://togogenome.org/gene/2546350:E1B03_RS23765 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSR5 ^@ Similarity ^@ Belongs to the RNase E/G family. RNase G subfamily. http://togogenome.org/gene/2546350:E1B03_RS17655 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMI3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS08205 ^@ http://purl.uniprot.org/uniprot/A0A4P6WN85 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/2546350:E1B03_RS04575 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJE2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS02020 ^@ http://purl.uniprot.org/uniprot/A0A4P6WF31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS24720 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTX1 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 1 family. http://togogenome.org/gene/2546350:E1B03_RS25630 ^@ http://purl.uniprot.org/uniprot/A0A4P6WUF1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/2546350:E1B03_RS02735 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKB9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class B bacterial acid phosphatase family.|||Binds 1 Mg(2+) ion per subunit.|||Homotetramer.|||Periplasm http://togogenome.org/gene/2546350:E1B03_RS21005 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRE5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the UbiD family. YclC subfamily.|||Binds 1 prenylated FMN (prenyl-FMN) per subunit.|||Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives. http://togogenome.org/gene/2546350:E1B03_RS22280 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAN9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.|||Cell membrane|||Heterodimer of a large and a small subunit. http://togogenome.org/gene/2546350:E1B03_RS24595 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPC0 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/2546350:E1B03_RS06675 ^@ http://purl.uniprot.org/uniprot/A0A4P6WN26 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS24395 ^@ http://purl.uniprot.org/uniprot/A0A4P6WP74 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2546350:E1B03_RS06925 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJN1 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/2546350:E1B03_RS13405 ^@ http://purl.uniprot.org/uniprot/A0A4V1AA75 ^@ Cofactor|||Function|||Subcellular Location Annotation ^@ Binds 4 [4Fe-4S] clusters per subunit.|||Membrane|||The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. http://togogenome.org/gene/2546350:E1B03_RS24745 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQP1 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS03490 ^@ http://purl.uniprot.org/uniprot/A0A4P6WI37 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Represses ulaG and the ulaABCDEF operon. http://togogenome.org/gene/2546350:E1B03_RS25260 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQW3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/2546350:E1B03_RS03930 ^@ http://purl.uniprot.org/uniprot/A0A4P6WG03 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/2546350:E1B03_RS22585 ^@ http://purl.uniprot.org/uniprot/A0A4P6WND3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/2546350:E1B03_RS02325 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHG3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2546350:E1B03_RS18460 ^@ http://purl.uniprot.org/uniprot/A0A4P6WR34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS09655 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS25525 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTI9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/2546350:E1B03_RS23720 ^@ http://purl.uniprot.org/uniprot/A0A4P6WVX4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/2546350:E1B03_RS13400 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the formate dehydrogenase gamma subunit family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS21405 ^@ http://purl.uniprot.org/uniprot/A0A4P6WUM4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetyltransferase family. ArgA subfamily.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/2546350:E1B03_RS16445 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSA2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Flagellar protein that affects chemotactic events.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS19805 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRT0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers. http://togogenome.org/gene/2546350:E1B03_RS07415 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9W6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2546350:E1B03_RS23685 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTD5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/2546350:E1B03_RS06885 ^@ http://purl.uniprot.org/uniprot/A0A4P6WN66 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Cell membrane|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS01090 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHT2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS04735 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acyl-CoA dehydrogenase family.|||Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/2546350:E1B03_RS16790 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQ83 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial microcompartment|||Belongs to the bacterial microcompartments protein family.|||The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low. http://togogenome.org/gene/2546350:E1B03_RS19605 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRN8 ^@ Function|||Similarity ^@ A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.|||Belongs to the NifU family. http://togogenome.org/gene/2546350:E1B03_RS11820 ^@ http://purl.uniprot.org/uniprot/A0A4P6WM14 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/2546350:E1B03_RS04960 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9R9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. FtsI subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.|||Cell inner membrane http://togogenome.org/gene/2546350:E1B03_RS12600 ^@ http://purl.uniprot.org/uniprot/A0A4V1AA60 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SlyA family.|||Homodimer.|||Transcription regulator that can specifically activate or repress expression of target genes. http://togogenome.org/gene/2546350:E1B03_RS05180 ^@ http://purl.uniprot.org/uniprot/A0A4P6WI81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS05975 ^@ http://purl.uniprot.org/uniprot/A0A4P6WH33 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EcpA/MatB fimbrillin family.|||Fimbrium|||Self-associates. Forms filaments. Interacts with EcpD. http://togogenome.org/gene/2546350:E1B03_RS08325 ^@ http://purl.uniprot.org/uniprot/A0A4P6WL77 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/2546350:E1B03_RS05545 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9T0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0294 family.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS07165 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMP3 ^@ Similarity ^@ Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. http://togogenome.org/gene/2546350:E1B03_RS06790 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMH7 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/2546350:E1B03_RS18535 ^@ http://purl.uniprot.org/uniprot/A0A4P6WR08 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS26040 ^@ http://purl.uniprot.org/uniprot/A0A4P6WX36 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS08700 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9Y9 ^@ Cofactor|||Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/2546350:E1B03_RS06935 ^@ http://purl.uniprot.org/uniprot/A0A4P6WN70 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/2546350:E1B03_RS14735 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRI3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.|||Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.|||Cell membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS14745 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNF9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS14165 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKN1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS04935 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJK4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/2546350:E1B03_RS05020 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJX1 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/2546350:E1B03_RS24150 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTP3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/2546350:E1B03_RS05355 ^@ http://purl.uniprot.org/uniprot/A0A4P6WGN9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/2546350:E1B03_RS00335 ^@ http://purl.uniprot.org/uniprot/A0A4P6WFY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS24030 ^@ http://purl.uniprot.org/uniprot/A0A4P6WVZ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/2546350:E1B03_RS13760 ^@ http://purl.uniprot.org/uniprot/A0A4P6WR96 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2546350:E1B03_RS22565 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSZ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS23030 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPI5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2546350:E1B03_RS18400 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAG8 ^@ Similarity ^@ Belongs to the UPF0304 family. http://togogenome.org/gene/2546350:E1B03_RS00530 ^@ http://purl.uniprot.org/uniprot/A0A4P6WK37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M23B family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS04975 ^@ http://purl.uniprot.org/uniprot/A0A4P6WI50 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS08500 ^@ http://purl.uniprot.org/uniprot/A0A4P6WK31 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).|||Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2546350:E1B03_RS03370 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJ88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS20525 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMF8 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/2546350:E1B03_RS23220 ^@ http://purl.uniprot.org/uniprot/A0A4P6WVP4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS24215 ^@ http://purl.uniprot.org/uniprot/A0A4P6WW56 ^@ Similarity ^@ Belongs to the SlyX family. http://togogenome.org/gene/2546350:E1B03_RS23755 ^@ http://purl.uniprot.org/uniprot/A0A4P6WXG2 ^@ Function|||Similarity ^@ Belongs to the peptidase U62 family.|||Metalloprotease involved in CcdA degradation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA). http://togogenome.org/gene/2546350:E1B03_RS12690 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQR9 ^@ Similarity ^@ Belongs to the Hha/YmoA/Cnu family. http://togogenome.org/gene/2546350:E1B03_RS03065 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHA4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KdgT transporter family.|||Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.|||Cell membrane http://togogenome.org/gene/2546350:E1B03_RS18320 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQX0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS24055 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSU6 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2546350:E1B03_RS21020 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMM9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoS subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. http://togogenome.org/gene/2546350:E1B03_RS03225 ^@ http://purl.uniprot.org/uniprot/A0A4P6WFM9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/2546350:E1B03_RS24545 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPB0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NfuA family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.|||Homodimer.|||Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. http://togogenome.org/gene/2546350:E1B03_RS09775 ^@ http://purl.uniprot.org/uniprot/A0A4P6WM11 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/2546350:E1B03_RS23395 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAR0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/2546350:E1B03_RS18375 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQ86 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2546350:E1B03_RS04635 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIL3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/2546350:E1B03_RS06820 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHJ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/2546350:E1B03_RS16475 ^@ http://purl.uniprot.org/uniprot/A0A4P6WM09 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/2546350:E1B03_RS02235 ^@ http://purl.uniprot.org/uniprot/A0A4P6WF72 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homodimer.|||Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer. http://togogenome.org/gene/2546350:E1B03_RS08340 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNU4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/2546350:E1B03_RS19235 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAI3 ^@ Similarity ^@ Belongs to the CcmL/EutN family. http://togogenome.org/gene/2546350:E1B03_RS06845 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMI6 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/2546350:E1B03_RS12550 ^@ http://purl.uniprot.org/uniprot/A0A4V1AA59 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase T family.|||Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.|||Homodimer.|||Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. http://togogenome.org/gene/2546350:E1B03_RS04665 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJR8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS04600 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9R2 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/2546350:E1B03_RS16345 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS09880 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKQ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MatP family.|||Cytoplasm|||Homodimer.|||Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain. http://togogenome.org/gene/2546350:E1B03_RS05345 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJS2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS23410 ^@ http://purl.uniprot.org/uniprot/A0A4P6WT92 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/2546350:E1B03_RS23815 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTJ3 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/2546350:E1B03_RS09995 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS19265 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQM3 ^@ Function|||Subcellular Location Annotation ^@ Bacterial microcompartment|||The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low. http://togogenome.org/gene/2546350:E1B03_RS08385 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS14405 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJS3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YciB family.|||Cell inner membrane|||Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. http://togogenome.org/gene/2546350:E1B03_RS23550 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNS7 ^@ Function|||Similarity ^@ Belongs to the peptidase C56 family.|||Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate. http://togogenome.org/gene/2546350:E1B03_RS05845 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMN6 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/2546350:E1B03_RS09360 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS15965 ^@ http://purl.uniprot.org/uniprot/A0A4P6WS20 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/2546350:E1B03_RS25740 ^@ http://purl.uniprot.org/uniprot/A0A4P6WUH1 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/2546350:E1B03_RS23320 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQ32 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/2546350:E1B03_RS19810 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQG8 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/2546350:E1B03_RS10835 ^@ http://purl.uniprot.org/uniprot/A0A4P6WXB6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein PotD/PotF family.|||Periplasm|||Required for the activity of the bacterial periplasmic transport system of putrescine. http://togogenome.org/gene/2546350:E1B03_RS25505 ^@ http://purl.uniprot.org/uniprot/A0A4P6WUB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS00505 ^@ http://purl.uniprot.org/uniprot/A0A4P6WG13 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/2546350:E1B03_RS21605 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPA1 ^@ Similarity ^@ Belongs to the FrmR/RcnR family. http://togogenome.org/gene/2546350:E1B03_RS21580 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNU0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2546350:E1B03_RS19385 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS19850 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAJ5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2546350:E1B03_RS09405 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRF2 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/2546350:E1B03_RS19535 ^@ http://purl.uniprot.org/uniprot/A0A4P6WU16 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/2546350:E1B03_RS20080 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNN2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamE family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/2546350:E1B03_RS17690 ^@ http://purl.uniprot.org/uniprot/A0A4P6WM59 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.|||Cell inner membrane|||Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.|||The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB). http://togogenome.org/gene/2546350:E1B03_RS17545 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0387 family.|||Cell membrane http://togogenome.org/gene/2546350:E1B03_RS14330 ^@ http://purl.uniprot.org/uniprot/A0A4P6WL25 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Cob(I)alamin adenosyltransferase family.|||Cytoplasm|||Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. http://togogenome.org/gene/2546350:E1B03_RS01070 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJ70 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/2546350:E1B03_RS02100 ^@ http://purl.uniprot.org/uniprot/A0A4P6WGU1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MetJ family.|||Cytoplasm|||Does not bind DNA by a helix-turn-helix motif.|||Homodimer.|||This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. http://togogenome.org/gene/2546350:E1B03_RS14335 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRJ1 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/2546350:E1B03_RS08570 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKF6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SeqA family.|||Cytoplasm|||Homodimer. Polymerizes to form helical filaments.|||Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. http://togogenome.org/gene/2546350:E1B03_RS22285 ^@ http://purl.uniprot.org/uniprot/A0A4P6WV38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS14280 ^@ http://purl.uniprot.org/uniprot/A0A4P6WL16 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LapA family.|||Cell inner membrane|||Involved in the assembly of lipopolysaccharide (LPS).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2546350:E1B03_RS19060 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRF1 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/2546350:E1B03_RS23670 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAR5 ^@ Similarity ^@ Belongs to the GST superfamily. HSP26 family. http://togogenome.org/gene/2546350:E1B03_RS09255 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLS8 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/2546350:E1B03_RS19345 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAI5 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/2546350:E1B03_RS16480 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSF3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Required for the assembly of the rivet at the earliest stage of flagellar biosynthesis.|||Role in flagellar biosynthesis. http://togogenome.org/gene/2546350:E1B03_RS24315 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTS0 ^@ Similarity ^@ Belongs to the phosphoribulokinase family. http://togogenome.org/gene/2546350:E1B03_RS13365 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMS8 ^@ Function|||Similarity ^@ Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein.|||Belongs to the SRA family. http://togogenome.org/gene/2546350:E1B03_RS20790 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRB5 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/2546350:E1B03_RS21885 ^@ http://purl.uniprot.org/uniprot/A0A4P6WV48 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/2546350:E1B03_RS16105 ^@ http://purl.uniprot.org/uniprot/A0A4P6WS96 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/2546350:E1B03_RS25510 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTH3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecB family.|||Cytoplasm|||Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.|||One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. http://togogenome.org/gene/2546350:E1B03_RS01275 ^@ http://purl.uniprot.org/uniprot/A0A4P6WH13 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. UvrD subfamily.|||Homodimer.|||Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. http://togogenome.org/gene/2546350:E1B03_RS11060 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIC3 ^@ Similarity ^@ Belongs to the gns family. http://togogenome.org/gene/2546350:E1B03_RS24035 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTI7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/2546350:E1B03_RS19390 ^@ http://purl.uniprot.org/uniprot/A0A4P6WM01 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48 family. BepA subfamily.|||Binds 1 zinc ion per subunit.|||Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.|||Periplasm http://togogenome.org/gene/2546350:E1B03_RS21875 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRQ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LysE/ArgO transporter (TC 2.A.75) family.|||Cell membrane|||Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS24640 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQM4 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/2546350:E1B03_RS05480 ^@ http://purl.uniprot.org/uniprot/A0A4P6WK42 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RcsF family.|||Cell outer membrane|||Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects. http://togogenome.org/gene/2546350:E1B03_RS05960 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLV6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS14980 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNG0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/2546350:E1B03_RS23435 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSL1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/2546350:E1B03_RS26075 ^@ http://purl.uniprot.org/uniprot/A0A4P6WX03 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.|||Belongs to the small heat shock protein (HSP20) family.|||Cytoplasm|||Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations. http://togogenome.org/gene/2546350:E1B03_RS03720 ^@ http://purl.uniprot.org/uniprot/A0A4P6WFX3 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS03300 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKL7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FrdC family.|||Cell membrane|||Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).|||Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones. http://togogenome.org/gene/2546350:E1B03_RS10565 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJG1 ^@ Function|||Similarity ^@ Belongs to the DUF177 domain family.|||Plays a role in synthesis, processing and/or stability of 23S rRNA. http://togogenome.org/gene/2546350:E1B03_RS20760 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS23995 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPY0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell inner membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS05390 ^@ http://purl.uniprot.org/uniprot/A0A4P6WGT8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/2546350:E1B03_RS01300 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9K3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure. http://togogenome.org/gene/2546350:E1B03_RS01720 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9L0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons. http://togogenome.org/gene/2546350:E1B03_RS00985 ^@ http://purl.uniprot.org/uniprot/A0A4P6WES3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits. http://togogenome.org/gene/2546350:E1B03_RS02045 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIQ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MenA family. Type 1 subfamily.|||Cell membrane|||Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).|||Membrane http://togogenome.org/gene/2546350:E1B03_RS00975 ^@ http://purl.uniprot.org/uniprot/A0A4P6WI82 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/2546350:E1B03_RS14780 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS18310 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQ28 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2546350:E1B03_RS23075 ^@ http://purl.uniprot.org/uniprot/A0A4P6WT34 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.|||Cell inner membrane|||Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).|||Membrane http://togogenome.org/gene/2546350:E1B03_RS04425 ^@ http://purl.uniprot.org/uniprot/A0A4P6WII1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer.|||The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. http://togogenome.org/gene/2546350:E1B03_RS03310 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHD7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Cell inner membrane|||Membrane|||Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD). http://togogenome.org/gene/2546350:E1B03_RS04435 ^@ http://purl.uniprot.org/uniprot/A0A4P6WM12 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.|||Homohexamer; trimer of homodimers. http://togogenome.org/gene/2546350:E1B03_RS01075 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIA4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/2546350:E1B03_RS15300 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS24170 ^@ http://purl.uniprot.org/uniprot/A0A4P6WP32 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/2546350:E1B03_RS06625 ^@ http://purl.uniprot.org/uniprot/A0A4P6WGE9 ^@ Function|||Similarity ^@ Belongs to the nucleoside phosphorylase PpnP family.|||Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. http://togogenome.org/gene/2546350:E1B03_RS19610 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQN8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/2546350:E1B03_RS18485 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMX6 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2546350:E1B03_RS04640 ^@ http://purl.uniprot.org/uniprot/A0A4P6WGD4 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/2546350:E1B03_RS02335 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKY7 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/2546350:E1B03_RS25515 ^@ http://purl.uniprot.org/uniprot/A0A4P6WR04 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. http://togogenome.org/gene/2546350:E1B03_RS15730 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNX9 ^@ Similarity ^@ Belongs to the UPF0181 family. http://togogenome.org/gene/2546350:E1B03_RS08390 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS14070 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNZ0 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/2546350:E1B03_RS05420 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9S8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS19615 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMZ1 ^@ Cofactor|||Function ^@ Binds 1 [2Fe-2S] cluster.|||Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. http://togogenome.org/gene/2546350:E1B03_RS06630 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9V1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RdgC family.|||May be involved in recombination.|||nucleoid http://togogenome.org/gene/2546350:E1B03_RS08830 ^@ http://purl.uniprot.org/uniprot/A0A4P6WUT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS25665 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAV2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/2546350:E1B03_RS16715 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAD6 ^@ Function|||Subcellular Location Annotation ^@ Bacterial microcompartment|||The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low. http://togogenome.org/gene/2546350:E1B03_RS09645 ^@ http://purl.uniprot.org/uniprot/A0A4P6WL50 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS19205 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMS4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial microcompartment|||Belongs to the EutB family.|||Binds between the large and small subunits.|||Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.|||The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards. http://togogenome.org/gene/2546350:E1B03_RS24230 ^@ http://purl.uniprot.org/uniprot/A0A4P6WW32 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.|||Cell inner membrane|||Interacts with the regulatory subunit KefG.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. http://togogenome.org/gene/2546350:E1B03_RS02320 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIC4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/2546350:E1B03_RS02375 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHH1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS19545 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAI9 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. http://togogenome.org/gene/2546350:E1B03_RS25685 ^@ http://purl.uniprot.org/uniprot/A0A4P6WR28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS24650 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPD2 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/2546350:E1B03_RS14740 ^@ http://purl.uniprot.org/uniprot/A0A4P6WP63 ^@ Similarity ^@ Belongs to the UPF0263 family. http://togogenome.org/gene/2546350:E1B03_RS13975 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKV3 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TtcA family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.|||Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.|||Cytoplasm|||Homodimer.|||The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster. http://togogenome.org/gene/2546350:E1B03_RS08295 ^@ http://purl.uniprot.org/uniprot/A0A4P6WH57 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TatA/E family. TatE subfamily.|||Cell inner membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA. http://togogenome.org/gene/2546350:E1B03_RS04455 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJP6 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/2546350:E1B03_RS16710 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKQ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial microcompartment|||Belongs to the bacterial microcompartments protein family.|||The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low. http://togogenome.org/gene/2546350:E1B03_RS01065 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9J9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/2546350:E1B03_RS19800 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTV9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/2546350:E1B03_RS24025 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAS1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/2546350:E1B03_RS18425 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQY8 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/2546350:E1B03_RS22295 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRT5 ^@ Similarity|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.|||Heterodimer of a large and a small subunit. http://togogenome.org/gene/2546350:E1B03_RS16955 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPI9 ^@ Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 2 family. http://togogenome.org/gene/2546350:E1B03_RS23785 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAR7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/2546350:E1B03_RS23660 ^@ http://purl.uniprot.org/uniprot/A0A4P6WVW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS03975 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJ40 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/2546350:E1B03_RS01520 ^@ http://purl.uniprot.org/uniprot/A0A4P6WH51 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS21995 ^@ http://purl.uniprot.org/uniprot/A0A4P6WV69 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS12175 ^@ http://purl.uniprot.org/uniprot/A0A4P6WN36 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.|||Belongs to the Lpp family.|||Cell outer membrane|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||cell wall http://togogenome.org/gene/2546350:E1B03_RS20095 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAJ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/2546350:E1B03_RS05310 ^@ http://purl.uniprot.org/uniprot/A0A4P6WME6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Periplasm http://togogenome.org/gene/2546350:E1B03_RS19410 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQK1 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/2546350:E1B03_RS04155 ^@ http://purl.uniprot.org/uniprot/A0A4P6WG39 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2546350:E1B03_RS20580 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAK8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Binds 1 Fe cation per subunit.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/2546350:E1B03_RS22645 ^@ http://purl.uniprot.org/uniprot/A0A4P6WVA3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/2546350:E1B03_RS23135 ^@ http://purl.uniprot.org/uniprot/A0A4P6WT45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2546350:E1B03_RS17230 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKY6 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).|||Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Cell membrane|||Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS14915 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNI3 ^@ Similarity ^@ Belongs to the UPF0162 family. http://togogenome.org/gene/2546350:E1B03_RS12005 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLX0 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/2546350:E1B03_RS22595 ^@ http://purl.uniprot.org/uniprot/A0A4P6WV96 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/2546350:E1B03_RS02055 ^@ http://purl.uniprot.org/uniprot/A0A4P6WF97 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/2546350:E1B03_RS19955 ^@ http://purl.uniprot.org/uniprot/A0A4P6WN56 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/2546350:E1B03_RS22995 ^@ http://purl.uniprot.org/uniprot/A0A4P6WVL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ElaB/YgaM/YqjD family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS17685 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPR9 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS02225 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIB2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS06750 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJ25 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/2546350:E1B03_RS22615 ^@ http://purl.uniprot.org/uniprot/A0A4P6WT04 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/2546350:E1B03_RS10505 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJF5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/2546350:E1B03_RS03845 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJH3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/2546350:E1B03_RS04995 ^@ http://purl.uniprot.org/uniprot/A0A4P6WGI6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS04720 ^@ http://purl.uniprot.org/uniprot/A0A4P6WI02 ^@ Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA. http://togogenome.org/gene/2546350:E1B03_RS15940 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLR7 ^@ Similarity|||Subunit ^@ Belongs to the KHG/KDPG aldolase family.|||Homotrimer. http://togogenome.org/gene/2546350:E1B03_RS16460 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLK8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Cell inner membrane|||FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS24990 ^@ http://purl.uniprot.org/uniprot/A0A4P6WU22 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RlmJ family.|||Monomer.|||Specifically methylates the adenine in position 2030 of 23S rRNA. http://togogenome.org/gene/2546350:E1B03_RS19990 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAJ7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS25700 ^@ http://purl.uniprot.org/uniprot/A0A4P6WR40 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/2546350:E1B03_RS18015 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQ20 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NapD family.|||Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.|||Cytoplasm|||Interacts with the cytoplasmic NapA precursor. http://togogenome.org/gene/2546350:E1B03_RS18665 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLM9 ^@ Similarity ^@ Belongs to the UPF0381 family. http://togogenome.org/gene/2546350:E1B03_RS09105 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLQ4 ^@ Function|||Similarity ^@ Belongs to the MoaB/Mog family.|||May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/2546350:E1B03_RS21650 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRQ2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2546350:E1B03_RS05350 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIW9 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2546350:E1B03_RS03705 ^@ http://purl.uniprot.org/uniprot/A0A4P6WG26 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/2546350:E1B03_RS21075 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAL7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PAPS reductase family. CysD subfamily.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/2546350:E1B03_RS15760 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPM6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homodimer.|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport. http://togogenome.org/gene/2546350:E1B03_RS21945 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgB family.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS03550 ^@ http://purl.uniprot.org/uniprot/A0A4P6WFT8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/2546350:E1B03_RS24110 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQE2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2546350:E1B03_RS11915 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMZ4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/2546350:E1B03_RS22015 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSM4 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/2546350:E1B03_RS17200 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPI7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/2546350:E1B03_RS23425 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPP6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/2546350:E1B03_RS21925 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRU8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/2546350:E1B03_RS05285 ^@ http://purl.uniprot.org/uniprot/A0A4P6WI96 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HesB/IscA family.|||Binds 1 iron-sulfur cluster per subunit.|||Homodimer.|||Required for insertion of 4Fe-4S clusters for at least IspG. http://togogenome.org/gene/2546350:E1B03_RS21760 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPC7 ^@ Function|||Similarity ^@ Belongs to the N(4)-acetylcytidine amidohydrolase family.|||Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C). http://togogenome.org/gene/2546350:E1B03_RS12965 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0060 family.|||Cell membrane http://togogenome.org/gene/2546350:E1B03_RS19170 ^@ http://purl.uniprot.org/uniprot/A0A4P6WN79 ^@ Similarity ^@ Belongs to the acetyltransferase family. YpeA subfamily. http://togogenome.org/gene/2546350:E1B03_RS20020 ^@ http://purl.uniprot.org/uniprot/A0A4P6WR01 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/2546350:E1B03_RS09695 ^@ http://purl.uniprot.org/uniprot/A0A4P6WL57 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/2546350:E1B03_RS24910 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPI0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS24820 ^@ http://purl.uniprot.org/uniprot/A0A4P6WWC9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell inner membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/2546350:E1B03_RS23180 ^@ http://purl.uniprot.org/uniprot/A0A4P6WVI5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS00355 ^@ http://purl.uniprot.org/uniprot/A0A4P6WED1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2546350:E1B03_RS23535 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSM9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RapZ-like family. RapZ subfamily.|||Homotrimer.|||Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS. http://togogenome.org/gene/2546350:E1B03_RS10205 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKV2 ^@ Cofactor|||Similarity ^@ Belongs to the WrbA family.|||Binds 1 FMN per monomer. http://togogenome.org/gene/2546350:E1B03_RS24995 ^@ http://purl.uniprot.org/uniprot/A0A4P6WT74 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/2546350:E1B03_RS03545 ^@ http://purl.uniprot.org/uniprot/A0A4P6WI45 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PriB family.|||Binds single-stranded DNA at the primosome assembly site (PAS).|||Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome. http://togogenome.org/gene/2546350:E1B03_RS08310 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLD3 ^@ Similarity ^@ Belongs to the UPF0250 family. http://togogenome.org/gene/2546350:E1B03_RS17320 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMD6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Periplasm http://togogenome.org/gene/2546350:E1B03_RS20635 ^@ http://purl.uniprot.org/uniprot/A0A4P6WR94 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/2546350:E1B03_RS09950 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJ77 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/2546350:E1B03_RS17125 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKW9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2546350:E1B03_RS01950 ^@ http://purl.uniprot.org/uniprot/A0A4P6WGR1 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/2546350:E1B03_RS13645 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2546350:E1B03_RS02340 ^@ http://purl.uniprot.org/uniprot/A0A4P6WEE8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/2546350:E1B03_RS21755 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS09915 ^@ http://purl.uniprot.org/uniprot/A0A4V1AA12 ^@ Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. http://togogenome.org/gene/2546350:E1B03_RS06655 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHE0 ^@ Function ^@ This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited. http://togogenome.org/gene/2546350:E1B03_RS06800 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJ34 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). http://togogenome.org/gene/2546350:E1B03_RS09500 ^@ http://purl.uniprot.org/uniprot/A0A4V1AA04 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein PotD/PotF family.|||Periplasm|||Required for the activity of the bacterial periplasmic transport system of putrescine. http://togogenome.org/gene/2546350:E1B03_RS24420 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQ52 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS16970 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKT9 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2546350:E1B03_RS25935 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAV7 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/2546350:E1B03_RS15810 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPN5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MgrB family.|||Cell membrane|||May form homooligomers. Probably interacts with the periplasmic domain of PhoQ.|||PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing. MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway. Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP. http://togogenome.org/gene/2546350:E1B03_RS24405 ^@ http://purl.uniprot.org/uniprot/A0A4P6WW60 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/2546350:E1B03_RS11045 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJN0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS18075 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMQ1 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the RcsB family.|||Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.|||Interacts with RcsD.|||Phosphorylated and activated by RcsD. http://togogenome.org/gene/2546350:E1B03_RS03135 ^@ http://purl.uniprot.org/uniprot/A0A4P6WFS7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Catalyzes the reversible hydration of fumarate to (S)-malate.|||Homodimer. http://togogenome.org/gene/2546350:E1B03_RS07170 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKU1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS01085 ^@ http://purl.uniprot.org/uniprot/A0A4P6WEU0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS16430 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSE3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Cell inner membrane|||FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS17980 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLB5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmB/CycW/HelB family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/2546350:E1B03_RS24120 ^@ http://purl.uniprot.org/uniprot/A0A4P6WP22 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/2546350:E1B03_RS08815 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLK4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the methylaspartate mutase GlmE subunit family.|||Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).|||Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer. http://togogenome.org/gene/2546350:E1B03_RS23235 ^@ http://purl.uniprot.org/uniprot/A0A4P6WVJ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SIS family. DiaA subfamily.|||Homotetramer; dimer of dimers.|||Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. http://togogenome.org/gene/2546350:E1B03_RS02720 ^@ http://purl.uniprot.org/uniprot/A0A4P6WL62 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. DnaB subfamily.|||Homohexamer.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. http://togogenome.org/gene/2546350:E1B03_RS11345 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMM1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs.|||Cytoplasm|||Interacts with TusE. http://togogenome.org/gene/2546350:E1B03_RS10470 ^@ http://purl.uniprot.org/uniprot/A0A4V1AA22 ^@ Function|||Similarity ^@ Belongs to the FlgM family.|||Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA. http://togogenome.org/gene/2546350:E1B03_RS05725 ^@ http://purl.uniprot.org/uniprot/A0A4P6WGY9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Cell inner membrane|||FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS02755 ^@ http://purl.uniprot.org/uniprot/A0A4P6WFK9 ^@ Function|||Subunit ^@ Homotetramer.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/2546350:E1B03_RS08870 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLL4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TolB family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.|||Periplasm|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/2546350:E1B03_RS24075 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAS2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/2546350:E1B03_RS09155 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLR2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS20530 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2546350:E1B03_RS11660 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQC1 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/2546350:E1B03_RS09465 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKJ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.|||Cell membrane http://togogenome.org/gene/2546350:E1B03_RS23975 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAS0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/2546350:E1B03_RS02345 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9M1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.|||Protein L10 is also a translational repressor protein. It controls the translation of the rplJL-rpoBC operon by binding to its mRNA. http://togogenome.org/gene/2546350:E1B03_RS17755 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMK0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pseudouridine-5'-phosphate glycosidase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.|||Homotrimer. http://togogenome.org/gene/2546350:E1B03_RS16605 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKN8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS03555 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLK9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/2546350:E1B03_RS20625 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNG2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/2546350:E1B03_RS00370 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9I6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS21355 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNR0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2546350:E1B03_RS19195 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRF6 ^@ Function|||Subcellular Location Annotation ^@ Bacterial microcompartment|||The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low. http://togogenome.org/gene/2546350:E1B03_RS04945 ^@ http://purl.uniprot.org/uniprot/A0A4P6WGI0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.|||nucleoid http://togogenome.org/gene/2546350:E1B03_RS18355 ^@ http://purl.uniprot.org/uniprot/A0A4P6WR14 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/2546350:E1B03_RS01820 ^@ http://purl.uniprot.org/uniprot/A0A4P6WE63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the formate dehydrogenase gamma subunit family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS25885 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAV6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS09270 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpX family.|||Cell outer membrane http://togogenome.org/gene/2546350:E1B03_RS24135 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTK9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/2546350:E1B03_RS13780 ^@ http://purl.uniprot.org/uniprot/A0A4P6WR13 ^@ Similarity ^@ Belongs to the FrmR/RcnR family. http://togogenome.org/gene/2546350:E1B03_RS07395 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJW4 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/2546350:E1B03_RS05940 ^@ http://purl.uniprot.org/uniprot/A0A4P6WGY1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.|||Cell membrane|||Homotetramer.|||Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine. http://togogenome.org/gene/2546350:E1B03_RS02330 ^@ http://purl.uniprot.org/uniprot/A0A4P6WF78 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NusG family.|||Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.|||Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination. http://togogenome.org/gene/2546350:E1B03_RS03095 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLD9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS16720 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSE4 ^@ Similarity ^@ Belongs to the diol/glycerol dehydratase large subunit family. http://togogenome.org/gene/2546350:E1B03_RS04615 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHY5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/2546350:E1B03_RS24620 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQ91 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS20670 ^@ http://purl.uniprot.org/uniprot/A0A4P6WR47 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2546350:E1B03_RS10560 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLI7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YceF subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/2546350:E1B03_RS01485 ^@ http://purl.uniprot.org/uniprot/A0A4P6WE20 ^@ Similarity ^@ Belongs to the Rht family. http://togogenome.org/gene/2546350:E1B03_RS09245 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9Z9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS24115 ^@ http://purl.uniprot.org/uniprot/A0A4P6WW38 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/2546350:E1B03_RS23345 ^@ http://purl.uniprot.org/uniprot/A0A4P6WVL2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 2 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/2546350:E1B03_RS02940 ^@ http://purl.uniprot.org/uniprot/A0A4P6WEP5 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS03255 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJ74 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.|||May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA. http://togogenome.org/gene/2546350:E1B03_RS20480 ^@ http://purl.uniprot.org/uniprot/A0A4P6WU72 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the AlaE exporter family.|||Cell inner membrane|||Exports L-alanine. http://togogenome.org/gene/2546350:E1B03_RS01605 ^@ http://purl.uniprot.org/uniprot/A0A4P6WGK3 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/2546350:E1B03_RS04985 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJL5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. FtsW subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell division. http://togogenome.org/gene/2546350:E1B03_RS12620 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJY1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer. http://togogenome.org/gene/2546350:E1B03_RS25890 ^@ http://purl.uniprot.org/uniprot/A0A4P6WX10 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS01920 ^@ http://purl.uniprot.org/uniprot/A0A4P6WE82 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KdgT transporter family.|||Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.|||Cell membrane http://togogenome.org/gene/2546350:E1B03_RS08415 ^@ http://purl.uniprot.org/uniprot/A0A4P6WK21 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/2546350:E1B03_RS01530 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKL5 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). http://togogenome.org/gene/2546350:E1B03_RS19355 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRI5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/2546350:E1B03_RS15670 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPP2 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/2546350:E1B03_RS12640 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQR1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpA subfamily.|||Cell inner membrane|||Membrane|||Proton-dependent permease that transports di- and tripeptides. http://togogenome.org/gene/2546350:E1B03_RS03140 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIR0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.|||Cell inner membrane|||Membrane|||Responsible for the transport of C4-dicarboxylates. http://togogenome.org/gene/2546350:E1B03_RS24085 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTJ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/2546350:E1B03_RS08335 ^@ http://purl.uniprot.org/uniprot/A0A4P6WID8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/2546350:E1B03_RS05825 ^@ http://purl.uniprot.org/uniprot/A0A4P6WH08 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/2546350:E1B03_RS05325 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLJ1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family.|||Cytoplasm|||Homotrimer. http://togogenome.org/gene/2546350:E1B03_RS10365 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPH5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. OpgH subfamily.|||Cell inner membrane|||Cell membrane|||Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).|||Membrane http://togogenome.org/gene/2546350:E1B03_RS06025 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIM7 ^@ Similarity ^@ Belongs to the UPF0386 family. http://togogenome.org/gene/2546350:E1B03_RS06785 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9V4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.|||Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers. http://togogenome.org/gene/2546350:E1B03_RS00600 ^@ http://purl.uniprot.org/uniprot/A0A4P6WEG6 ^@ Similarity ^@ Belongs to the CcdB toxin family. http://togogenome.org/gene/2546350:E1B03_RS10595 ^@ http://purl.uniprot.org/uniprot/A0A4P6WL19 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS07120 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKT3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2546350:E1B03_RS24020 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNZ8 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/2546350:E1B03_RS08330 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKB2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. MrdA subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall.|||Cell inner membrane http://togogenome.org/gene/2546350:E1B03_RS06530 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9U9 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/2546350:E1B03_RS25290 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAU5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/2546350:E1B03_RS01035 ^@ http://purl.uniprot.org/uniprot/A0A4P6WET1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/2546350:E1B03_RS08265 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJY6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS01390 ^@ http://purl.uniprot.org/uniprot/A0A4P6WUL5 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Involved in a late step of protoheme IX synthesis.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS24310 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQ34 ^@ Similarity ^@ Belongs to the UPF0270 family. http://togogenome.org/gene/2546350:E1B03_RS20640 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNV3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS08210 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLB3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Rnk family.|||Interacts with the RNA polymerase.|||May act as an anti-Gre factor. http://togogenome.org/gene/2546350:E1B03_RS12545 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIX8 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family. Monothiol subfamily.|||Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. http://togogenome.org/gene/2546350:E1B03_RS11910 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJL8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/2546350:E1B03_RS18130 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTC8 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. http://togogenome.org/gene/2546350:E1B03_RS07075 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHK1 ^@ Similarity ^@ Belongs to the Hha/YmoA/Cnu family. http://togogenome.org/gene/2546350:E1B03_RS15840 ^@ http://purl.uniprot.org/uniprot/A0A4P6WS53 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ProQ family.|||Cytoplasm|||RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. http://togogenome.org/gene/2546350:E1B03_RS14765 ^@ http://purl.uniprot.org/uniprot/A0A4P6WL94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS01990 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJS7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/2546350:E1B03_RS06880 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHK2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heme-copper respiratory oxidase family.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS03895 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9P9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RraB family.|||Cytoplasm|||Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.|||Interacts with the C-terminal region of Rne. http://togogenome.org/gene/2546350:E1B03_RS05805 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9T5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/2546350:E1B03_RS09720 ^@ http://purl.uniprot.org/uniprot/A0A4P6WP68 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/2546350:E1B03_RS15690 ^@ http://purl.uniprot.org/uniprot/A0A4P6WK98 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family. CntA subfamily.|||Binds 1 Fe cation per subunit.|||Binds 1 [2Fe-2S] cluster per subunit.|||Composed of an oxygenase subunit and a reductase subunit.|||Converts carnitine to trimethylamine and malic semialdehyde. http://togogenome.org/gene/2546350:E1B03_RS05320 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9S6 ^@ Similarity ^@ Belongs to the UPF0325 family. http://togogenome.org/gene/2546350:E1B03_RS01095 ^@ http://purl.uniprot.org/uniprot/A0A4P6WGY5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS15780 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNY7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/2546350:E1B03_RS16665 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAD5 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/2546350:E1B03_RS23845 ^@ http://purl.uniprot.org/uniprot/A0A4P6WVV3 ^@ Function|||Similarity ^@ Belongs to the Dus family. DusB subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/2546350:E1B03_RS00325 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIL4 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/2546350:E1B03_RS24125 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAS3 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/2546350:E1B03_RS24065 ^@ http://purl.uniprot.org/uniprot/A0A4P6WW29 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/2546350:E1B03_RS25500 ^@ http://purl.uniprot.org/uniprot/A0A4P6WWT8 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/2546350:E1B03_RS03405 ^@ http://purl.uniprot.org/uniprot/A0A4P6WEW9 ^@ Function|||Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily.|||HflC and HflK could regulate a protease. http://togogenome.org/gene/2546350:E1B03_RS08935 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9Z3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Homodimer. http://togogenome.org/gene/2546350:E1B03_RS12045 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQA0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2546350:E1B03_RS01565 ^@ http://purl.uniprot.org/uniprot/A0A4P6WI04 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RfaH family.|||Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.|||Interacts with both the nontemplate DNA and the RNA polymerase (RNAP). http://togogenome.org/gene/2546350:E1B03_RS16365 ^@ http://purl.uniprot.org/uniprot/A0A4P6WP91 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sigma-70 factor family. FliA subfamily.|||Cytoplasm|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes. http://togogenome.org/gene/2546350:E1B03_RS20055 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRW1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS18630 ^@ http://purl.uniprot.org/uniprot/A0A4P6WR60 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M74 family.|||Binds 2 Zn(2+) ions per subunit. Zn(2+) ion 1 is bound in the active site. Zn(2+) ion 2 is bound at the dimer interface by residues from both subunits.|||Dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus.|||Periplasm http://togogenome.org/gene/2546350:E1B03_RS19655 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRP7 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS14910 ^@ http://purl.uniprot.org/uniprot/A0A4P6WP92 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS04305 ^@ http://purl.uniprot.org/uniprot/A0A4P6WG67 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThrE exporter (TC 2.A.79) family.|||Cell inner membrane|||Involved in succinate export with YjjP. Both proteins are required for export.|||Membrane|||The transporter is composed of YjjB and YjjP. http://togogenome.org/gene/2546350:E1B03_RS17795 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQP0 ^@ Function|||Similarity ^@ Belongs to the carbohydrate kinase PfkB family.|||Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate. http://togogenome.org/gene/2546350:E1B03_RS10825 ^@ http://purl.uniprot.org/uniprot/A0A4V1AA28 ^@ Function|||Similarity ^@ Belongs to the ROK (NagC/XylR) family. NagK subfamily.|||Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. http://togogenome.org/gene/2546350:E1B03_RS04625 ^@ http://purl.uniprot.org/uniprot/A0A4P6WGG7 ^@ Function|||Similarity ^@ Belongs to the ribF family.|||Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. http://togogenome.org/gene/2546350:E1B03_RS17735 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPS7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS21855 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRL8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/2546350:E1B03_RS09905 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPK5 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/2546350:E1B03_RS21840 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAN1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LysR transcriptional regulatory family.|||Controls the transcription of genes involved in arginine and lysine metabolism.|||Homodimer. http://togogenome.org/gene/2546350:E1B03_RS14905 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS00565 ^@ http://purl.uniprot.org/uniprot/A0A4P6WI11 ^@ Function|||Similarity ^@ Belongs to the FumD family.|||In vitro catalyzes the addition of water to fumarate, forming malate. Cannot catalyze the reverse reaction. Cannot use the cis-isomer maleate as substrate. http://togogenome.org/gene/2546350:E1B03_RS11520 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJF2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0756 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2546350:E1B03_RS23835 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNX3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/2546350:E1B03_RS24045 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPY8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/2546350:E1B03_RS08825 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIA6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the methylaspartate mutase GlmS subunit family.|||Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).|||Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer. http://togogenome.org/gene/2546350:E1B03_RS12195 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS04825 ^@ http://purl.uniprot.org/uniprot/A0A4P6WGJ9 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/2546350:E1B03_RS00970 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJ49 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/2546350:E1B03_RS23900 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS11475 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS22945 ^@ http://purl.uniprot.org/uniprot/A0A4P6WVK7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Has been proposed to be a redox modulator.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS21965 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSL7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS03745 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJF3 ^@ Function|||Similarity ^@ Belongs to the MurCDEF family. Mpl subfamily.|||Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate. http://togogenome.org/gene/2546350:E1B03_RS19340 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLZ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS03435 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIV4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.|||Cytoplasm|||Homodimer.|||Specifically methylates the ribose of guanosine 2251 in 23S rRNA. http://togogenome.org/gene/2546350:E1B03_RS15765 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNV4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS05370 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9S7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS25480 ^@ http://purl.uniprot.org/uniprot/A0A4P6WR05 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.|||Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.|||Cell membrane http://togogenome.org/gene/2546350:E1B03_RS01780 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIK5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2546350:E1B03_RS09870 ^@ http://purl.uniprot.org/uniprot/A0A4P6WP96 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thioester dehydratase family. FabA subfamily.|||Cytoplasm|||Homodimer.|||Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. http://togogenome.org/gene/2546350:E1B03_RS04460 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHV8 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/2546350:E1B03_RS03415 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKN2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/2546350:E1B03_RS05790 ^@ http://purl.uniprot.org/uniprot/A0A4P6WGV4 ^@ Function|||Similarity ^@ Belongs to the FlgM family.|||Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA. http://togogenome.org/gene/2546350:E1B03_RS18265 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMD3 ^@ Caution|||Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.|||Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2546350:E1B03_RS09295 ^@ http://purl.uniprot.org/uniprot/A0A4V1AA00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YkuD family.|||Periplasm http://togogenome.org/gene/2546350:E1B03_RS25725 ^@ http://purl.uniprot.org/uniprot/A0A4P6WUE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS09955 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPL2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dsrC/tusE family.|||Cytoplasm|||Interacts with the TusBCD complex. Interacts with MnmA.|||Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD. http://togogenome.org/gene/2546350:E1B03_RS17970 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMN4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmD/CycX/HelD family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/2546350:E1B03_RS16410 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLK1 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/2546350:E1B03_RS05395 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJT3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/2546350:E1B03_RS14290 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJQ9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase II family.|||Binds 1 zinc ion per subunit.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||Homodimer. http://togogenome.org/gene/2546350:E1B03_RS22580 ^@ http://purl.uniprot.org/uniprot/A0A4P6WVF2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.|||Homooctamer. http://togogenome.org/gene/2546350:E1B03_RS14820 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRR5 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/2546350:E1B03_RS00445 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHZ3 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Member of a two-component regulatory system. http://togogenome.org/gene/2546350:E1B03_RS05005 ^@ http://purl.uniprot.org/uniprot/A0A4P6WFN5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsQ/DivIB family. FtsQ subfamily.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/2546350:E1B03_RS23965 ^@ http://purl.uniprot.org/uniprot/A0A4P6WW12 ^@ Similarity ^@ Belongs to the Smg family. http://togogenome.org/gene/2546350:E1B03_RS21450 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAM4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2546350:E1B03_RS00510 ^@ http://purl.uniprot.org/uniprot/A0A4P6WEI6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS21030 ^@ http://purl.uniprot.org/uniprot/A0A4P6WUF5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.|||Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS21350 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0382 family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS23850 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTF7 ^@ Function|||Similarity|||Subunit ^@ Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.|||Belongs to the transcriptional regulatory Fis family.|||Homodimer. http://togogenome.org/gene/2546350:E1B03_RS19875 ^@ http://purl.uniprot.org/uniprot/A0A4P6WN46 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DEAD box helicase family. SrmB subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.|||Interacts with the 50S ribosomal subunit. http://togogenome.org/gene/2546350:E1B03_RS23480 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTE0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD). http://togogenome.org/gene/2546350:E1B03_RS01240 ^@ http://purl.uniprot.org/uniprot/A0A4P6WDY0 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/2546350:E1B03_RS13620 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GhoT/OrtT toxin family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS16765 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAD7 ^@ Similarity ^@ Belongs to the CcmL/EutN family. http://togogenome.org/gene/2546350:E1B03_RS22980 ^@ http://purl.uniprot.org/uniprot/A0A4P6WT69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS16005 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKE6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/2546350:E1B03_RS03205 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHC0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.|||Cell inner membrane|||Membrane|||Responsible for the transport of C4-dicarboxylates. http://togogenome.org/gene/2546350:E1B03_RS19820 ^@ http://purl.uniprot.org/uniprot/A0A4P6WN32 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/2546350:E1B03_RS18020 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMP2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NapF family.|||Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.|||Cytoplasm|||Interacts with the cytoplasmic NapA precursor. http://togogenome.org/gene/2546350:E1B03_RS23775 ^@ http://purl.uniprot.org/uniprot/A0A4P6WVY4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Cell inner membrane|||Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS03030 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2546350:E1B03_RS00610 ^@ http://purl.uniprot.org/uniprot/A0A4P6WDL0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TraT lipoprotein family.|||Cell outer membrane|||Membrane|||Responsible for preventing unproductive conjugation between bacteria carrying like plasmids. http://togogenome.org/gene/2546350:E1B03_RS04160 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLW9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS03855 ^@ http://purl.uniprot.org/uniprot/A0A4P6WG51 ^@ Similarity|||Subunit ^@ Belongs to the RutC family.|||Homotrimer. http://togogenome.org/gene/2546350:E1B03_RS17710 ^@ http://purl.uniprot.org/uniprot/A0A4P6WT57 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer.|||Toroid-shaped homodecamer, composed of two pentamers of five dimers. http://togogenome.org/gene/2546350:E1B03_RS01825 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9L2 ^@ Cofactor|||Function|||Subcellular Location Annotation ^@ Binds 4 [4Fe-4S] clusters per subunit.|||Membrane|||The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. http://togogenome.org/gene/2546350:E1B03_RS23820 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSS3 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/2546350:E1B03_RS04535 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTW0 ^@ Function|||Similarity ^@ Belongs to the thr operon leader peptide family.|||This protein is involved in control of the biosynthesis of threonine. http://togogenome.org/gene/2546350:E1B03_RS22005 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAN4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Monomer.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/2546350:E1B03_RS11935 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIP6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/2546350:E1B03_RS20025 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNM5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/2546350:E1B03_RS12855 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJ35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.|||Catalyzes the excretion of spermidine.|||Cell inner membrane|||Cell membrane|||Forms a complex with MdtJ.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS03865 ^@ http://purl.uniprot.org/uniprot/A0A4P6WI95 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/2546350:E1B03_RS16095 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRI8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CheZ family.|||Cytoplasm|||Homodimer.|||Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). http://togogenome.org/gene/2546350:E1B03_RS14360 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNZ7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2546350:E1B03_RS20035 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMA1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/2546350:E1B03_RS03200 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJ65 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CutA family.|||Binds 1 copper ion per subunit.|||Cytoplasm|||Homotrimer.|||Involved in resistance toward heavy metals. http://togogenome.org/gene/2546350:E1B03_RS09785 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIR4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2546350:E1B03_RS05385 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIB9 ^@ Similarity ^@ Belongs to the skp family. http://togogenome.org/gene/2546350:E1B03_RS17725 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSU8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS18465 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQ60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/2546350:E1B03_RS06765 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.|||Cell outer membrane http://togogenome.org/gene/2546350:E1B03_RS24100 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTN5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/2546350:E1B03_RS24750 ^@ http://purl.uniprot.org/uniprot/A0A4P6WWE4 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/2546350:E1B03_RS21570 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSG6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the KduI family.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. http://togogenome.org/gene/2546350:E1B03_RS02435 ^@ http://purl.uniprot.org/uniprot/A0A4P6WL09 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/2546350:E1B03_RS21380 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMT8 ^@ Function ^@ Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. http://togogenome.org/gene/2546350:E1B03_RS10520 ^@ http://purl.uniprot.org/uniprot/A0A4P6WI51 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.|||In the C-terminal section; belongs to the glycosyl hydrolase 73 family.|||In the N-terminal section; belongs to the FlgJ family.|||Periplasm http://togogenome.org/gene/2546350:E1B03_RS22600 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSV7 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/2546350:E1B03_RS07135 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKM4 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/2546350:E1B03_RS05170 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLG5 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/2546350:E1B03_RS17920 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YejK family.|||nucleoid http://togogenome.org/gene/2546350:E1B03_RS11590 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJG4 ^@ Function|||Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.|||Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. http://togogenome.org/gene/2546350:E1B03_RS19240 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTK0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial microcompartment|||Belongs to the bacterial microcompartments protein family.|||The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low. http://togogenome.org/gene/2546350:E1B03_RS05120 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLF4 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/2546350:E1B03_RS17990 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSZ2 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NapC/NirT/NrfH family.|||Binds 4 heme groups per subunit.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS24160 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQF0 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/2546350:E1B03_RS19325 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0370 family.|||Cell membrane http://togogenome.org/gene/2546350:E1B03_RS24525 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTV8 ^@ Function|||Similarity ^@ Belongs to the FeoC family.|||May function as a transcriptional regulator that controls feoABC expression. http://togogenome.org/gene/2546350:E1B03_RS01745 ^@ http://purl.uniprot.org/uniprot/A0A4P6WI33 ^@ Function|||Similarity ^@ Belongs to the aldolase LacD family.|||Cleaves 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP) to form dihydroxyacetone phosphate (DHAP) and 3-sulfolactaldehyde (SLA). http://togogenome.org/gene/2546350:E1B03_RS24765 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAT5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoH subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. http://togogenome.org/gene/2546350:E1B03_RS23330 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNP5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/2546350:E1B03_RS24040 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSL0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/2546350:E1B03_RS19070 ^@ http://purl.uniprot.org/uniprot/A0A4P6WN69 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/2546350:E1B03_RS09560 ^@ http://purl.uniprot.org/uniprot/A0A4V1AA05 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/2546350:E1B03_RS03725 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLP6 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS06930 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHL0 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/2546350:E1B03_RS08860 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9Z2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbD/TolR family.|||Cell inner membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/2546350:E1B03_RS00495 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS01055 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKE3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/2546350:E1B03_RS11825 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJY3 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/2546350:E1B03_RS16635 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiM family.|||Cell membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Membrane|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/2546350:E1B03_RS24800 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM86 family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS00320 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9I5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArsB family.|||Cell membrane|||Involved in arsenical resistance. Thought to form the channel of an arsenite pump.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS02085 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9L7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2546350:E1B03_RS14795 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone-like protein H-NS family.|||nucleoid http://togogenome.org/gene/2546350:E1B03_RS08710 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLI8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/2546350:E1B03_RS03275 ^@ http://purl.uniprot.org/uniprot/A0A4P6WI08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS16795 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPG1 ^@ Function|||Subcellular Location Annotation ^@ Bacterial microcompartment|||The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low. http://togogenome.org/gene/2546350:E1B03_RS06715 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJK0 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. http://togogenome.org/gene/2546350:E1B03_RS05715 ^@ http://purl.uniprot.org/uniprot/A0A4P6WK69 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/2546350:E1B03_RS08875 ^@ http://purl.uniprot.org/uniprot/A0A4P6WK93 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Pal lipoprotein family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/2546350:E1B03_RS06920 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKI7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/2546350:E1B03_RS04670 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHZ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS15665 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLA3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily.|||Interacts with MinC and FtsZ.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS24505 ^@ http://purl.uniprot.org/uniprot/A0A4P6WW77 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family. GreB subfamily.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length. http://togogenome.org/gene/2546350:E1B03_RS23515 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTB0 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system. http://togogenome.org/gene/2546350:E1B03_RS18340 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLH6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/2546350:E1B03_RS21165 ^@ http://purl.uniprot.org/uniprot/A0A4P6WP34 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2546350:E1B03_RS18905 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAH7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS06600 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHD1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS06745 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKM7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/2546350:E1B03_RS08850 ^@ http://purl.uniprot.org/uniprot/A0A4P6WP25 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/2546350:E1B03_RS15995 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLS7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/2546350:E1B03_RS23710 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQ89 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LDH/MDH superfamily. MDH type 1 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate.|||Homodimer. http://togogenome.org/gene/2546350:E1B03_RS14930 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNF0 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/2546350:E1B03_RS23680 ^@ http://purl.uniprot.org/uniprot/A0A4P6WVS1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/2546350:E1B03_RS03395 ^@ http://purl.uniprot.org/uniprot/A0A4P6WFR0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/2546350:E1B03_RS08965 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKM0 ^@ Similarity ^@ Belongs to the ModE family. http://togogenome.org/gene/2546350:E1B03_RS00315 ^@ http://purl.uniprot.org/uniprot/A0A4P6WDF9 ^@ Function|||Similarity ^@ Anion-transporting ATPase.|||Belongs to the arsA ATPase family. http://togogenome.org/gene/2546350:E1B03_RS10945 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQ03 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/2546350:E1B03_RS22395 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRV4 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/2546350:E1B03_RS25695 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTL4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/2546350:E1B03_RS05010 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9S0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/2546350:E1B03_RS24180 ^@ http://purl.uniprot.org/uniprot/A0A4P6WW21 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/2546350:E1B03_RS17585 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQK2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS19815 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQT0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/2546350:E1B03_RS24015 ^@ http://purl.uniprot.org/uniprot/A0A4P6WW20 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/2546350:E1B03_RS02615 ^@ http://purl.uniprot.org/uniprot/A0A4P6WL43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PsiE family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS03425 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHF1 ^@ Cofactor|||Function ^@ Binds 1 [2Fe-2S] cluster per subunit.|||Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity. http://togogenome.org/gene/2546350:E1B03_RS00960 ^@ http://purl.uniprot.org/uniprot/A0A4P6WDT2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/2546350:E1B03_RS05335 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIA7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/2546350:E1B03_RS16145 ^@ http://purl.uniprot.org/uniprot/A0A4P6WP56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS04595 ^@ http://purl.uniprot.org/uniprot/A0A4P6WFG5 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/2546350:E1B03_RS21890 ^@ http://purl.uniprot.org/uniprot/A0A4P6WN10 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/2546350:E1B03_RS08395 ^@ http://purl.uniprot.org/uniprot/A0A4P6WH75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS08195 ^@ http://purl.uniprot.org/uniprot/A0A4P6WH43 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Cytoplasm|||Homodimer.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/2546350:E1B03_RS24815 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAT6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sulfur carrier protein TusA family.|||Cytoplasm|||Interacts with IscS.|||Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin. http://togogenome.org/gene/2546350:E1B03_RS19740 ^@ http://purl.uniprot.org/uniprot/A0A4P6WM60 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/2546350:E1B03_RS01290 ^@ http://purl.uniprot.org/uniprot/A0A4P6WDZ2 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/2546350:E1B03_RS09125 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS06915 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHH8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/2546350:E1B03_RS01545 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJF6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/2546350:E1B03_RS14950 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAA4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/2546350:E1B03_RS04820 ^@ http://purl.uniprot.org/uniprot/A0A4P6WI25 ^@ Domain|||Function|||Subcellular Location Annotation|||Subunit ^@ Cell inner membrane|||Homodimer.|||Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.|||The transmembrane domain is a dimerization domain. http://togogenome.org/gene/2546350:E1B03_RS13160 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMK7 ^@ Similarity|||Subunit ^@ Belongs to the glutaminase family.|||Homotetramer. http://togogenome.org/gene/2546350:E1B03_RS07145 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHP5 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/2546350:E1B03_RS02295 ^@ http://purl.uniprot.org/uniprot/A0A4P6WFD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic pantothenate kinase family.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS16315 ^@ http://purl.uniprot.org/uniprot/A0A4P6WP81 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Cell inner membrane|||Membrane|||This protein catalyzes the committed step to the synthesis of the acidic phospholipids. http://togogenome.org/gene/2546350:E1B03_RS04470 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJC7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/2546350:E1B03_RS03850 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHM5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/2546350:E1B03_RS17305 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Periplasm http://togogenome.org/gene/2546350:E1B03_RS18750 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the urease gamma subunit family.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS05905 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9T7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS05655 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9T2 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||Homotetramer.|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/2546350:E1B03_RS23745 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AaeX family.|||Cell membrane http://togogenome.org/gene/2546350:E1B03_RS10625 ^@ http://purl.uniprot.org/uniprot/A0A4P6WI69 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/2546350:E1B03_RS02360 ^@ http://purl.uniprot.org/uniprot/A0A4P6WGY2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/2546350:E1B03_RS16960 ^@ http://purl.uniprot.org/uniprot/A0A4P6WM85 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/2546350:E1B03_RS02695 ^@ http://purl.uniprot.org/uniprot/A0A4P6WH35 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/2546350:E1B03_RS07055 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9V9 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2546350:E1B03_RS03150 ^@ http://purl.uniprot.org/uniprot/A0A4P6WFL7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS15725 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPQ6 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/2546350:E1B03_RS11340 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HflD family.|||Cell membrane|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS23885 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNY3 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/2546350:E1B03_RS19830 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQX2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/2546350:E1B03_RS16910 ^@ http://purl.uniprot.org/uniprot/A0A4P6WM77 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/2546350:E1B03_RS01215 ^@ http://purl.uniprot.org/uniprot/A0A4P6WEV7 ^@ Similarity ^@ Belongs to the UPF0438 family. http://togogenome.org/gene/2546350:E1B03_RS13500 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKN7 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/2546350:E1B03_RS05015 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLD8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/2546350:E1B03_RS20455 ^@ http://purl.uniprot.org/uniprot/A0A4P6WR71 ^@ Similarity ^@ Belongs to the UPF0057 (PMP3) family. http://togogenome.org/gene/2546350:E1B03_RS09830 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZapC family.|||Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.|||Cytoplasm|||Interacts directly with FtsZ. http://togogenome.org/gene/2546350:E1B03_RS18330 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMU8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2546350:E1B03_RS03315 ^@ http://purl.uniprot.org/uniprot/A0A4P6WFV5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.|||Homodimer.|||With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P. http://togogenome.org/gene/2546350:E1B03_RS15330 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNN8 ^@ Function|||Similarity ^@ Belongs to the DadA oxidoreductase family.|||Oxidative deamination of D-amino acids. http://togogenome.org/gene/2546350:E1B03_RS10755 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJJ1 ^@ Similarity ^@ Belongs to the UPF0227 family. http://togogenome.org/gene/2546350:E1B03_RS13515 ^@ http://purl.uniprot.org/uniprot/A0A4V1AA77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS19580 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNF8 ^@ Function|||Similarity ^@ Belongs to the IscX family.|||May function as iron donor in the assembly of iron-sulfur clusters. http://togogenome.org/gene/2546350:E1B03_RS08915 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKK9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane|||Required for nicotinamide riboside transport across the inner membrane. http://togogenome.org/gene/2546350:E1B03_RS25245 ^@ http://purl.uniprot.org/uniprot/A0A4P6WWP6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS20765 ^@ http://purl.uniprot.org/uniprot/A0A4P6WUB6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS12625 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNA3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2546350:E1B03_RS01435 ^@ http://purl.uniprot.org/uniprot/A0A4P6WE11 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.|||FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the top DNA strands. http://togogenome.org/gene/2546350:E1B03_RS15795 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKB3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS04385 ^@ http://purl.uniprot.org/uniprot/A0A4P6WFC7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/2546350:E1B03_RS26005 ^@ http://purl.uniprot.org/uniprot/A0A4P6WR80 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS08515 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKE7 ^@ Similarity ^@ Belongs to the outer membrane porin (Opr) (TC 1.B.25) family. http://togogenome.org/gene/2546350:E1B03_RS17860 ^@ http://purl.uniprot.org/uniprot/A0A4P6WT82 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/2546350:E1B03_RS19065 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQI9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS18315 ^@ http://purl.uniprot.org/uniprot/A0A4P6WME0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4 family.|||Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS12555 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQG7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the glyoxalase I family.|||Binds 1 nickel ion per subunit.|||Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. http://togogenome.org/gene/2546350:E1B03_RS10570 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPV7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/2546350:E1B03_RS01665 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9K9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbA subfamily.|||Periplasm http://togogenome.org/gene/2546350:E1B03_RS05195 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIV0 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/2546350:E1B03_RS06870 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKI0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase bacterial subunit 4 family.|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS21055 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRF4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsB family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/2546350:E1B03_RS23495 ^@ http://purl.uniprot.org/uniprot/A0A4P6WVT6 ^@ Similarity|||Subunit ^@ Belongs to the SIS family. GutQ/KpsF subfamily.|||Homotetramer. http://togogenome.org/gene/2546350:E1B03_RS03860 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJ23 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the PyrI family.|||Binds 1 zinc ion per subunit.|||Contains catalytic and regulatory chains.|||Heterododecamer (2C3:3R2) of six catalytic PyrB chains organized as two trimers (C3), and six regulatory PyrI chains organized as three dimers (R2).|||Involved in allosteric regulation of aspartate carbamoyltransferase. http://togogenome.org/gene/2546350:E1B03_RS01030 ^@ http://purl.uniprot.org/uniprot/A0A4P6WGC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS09865 ^@ http://purl.uniprot.org/uniprot/A0A4V1AA11 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ribosome modulation factor family.|||Cytoplasm|||During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes). http://togogenome.org/gene/2546350:E1B03_RS07215 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMQ2 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/2546350:E1B03_RS10815 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPY7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.|||Cell inner membrane|||Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.|||The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE). http://togogenome.org/gene/2546350:E1B03_RS19405 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS18675 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTA7 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/2546350:E1B03_RS22260 ^@ http://purl.uniprot.org/uniprot/A0A4P6WS11 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/2546350:E1B03_RS24955 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQS1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpB subfamily.|||Cell inner membrane|||Membrane|||Proton-dependent permease that transports di- and tripeptides. http://togogenome.org/gene/2546350:E1B03_RS09120 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLK5 ^@ Similarity|||Subunit ^@ Belongs to the MoaE family.|||Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis. http://togogenome.org/gene/2546350:E1B03_RS05230 ^@ http://purl.uniprot.org/uniprot/A0A4P6WI89 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DksA family.|||Cytoplasm|||Interacts directly with the RNA polymerase.|||Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. http://togogenome.org/gene/2546350:E1B03_RS22055 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAN5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Fe(2+)-trafficking protein family.|||Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.|||Monomer. http://togogenome.org/gene/2546350:E1B03_RS12680 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMD2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/2546350:E1B03_RS04950 ^@ http://purl.uniprot.org/uniprot/A0A4P6WM99 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/2546350:E1B03_RS02815 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIK9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS10300 ^@ http://purl.uniprot.org/uniprot/A0A4V1AA19 ^@ Function|||Similarity ^@ Belongs to the CsgG family.|||May be involved in the biogenesis of curli organelles. http://togogenome.org/gene/2546350:E1B03_RS24060 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQD6 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/2546350:E1B03_RS01725 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJH9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/2546350:E1B03_RS01150 ^@ http://purl.uniprot.org/uniprot/A0A4P6WER3 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS15660 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNT4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/2546350:E1B03_RS21815 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPD3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.|||Belongs to the ZapA family. Type 1 subfamily.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/2546350:E1B03_RS24070 ^@ http://purl.uniprot.org/uniprot/A0A4P6WP11 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/2546350:E1B03_RS07005 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKR8 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/2546350:E1B03_RS02015 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHC3 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Activity of this regulatory enzyme is affected by several metabolites. Allosterically and non-competitively inhibited by fructose 1,6-bisphosphate (FBP) and unphosphorylated phosphocarrier protein EIIA-Glc (III-Glc), an integral component of the bacterial phosphotransferase (PTS) system.|||Belongs to the FGGY kinase family.|||Homotetramer and homodimer (in equilibrium). Heterodimer with EIIA-Glc. Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/2546350:E1B03_RS16000 ^@ http://purl.uniprot.org/uniprot/A0A4P6WS78 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/2546350:E1B03_RS23310 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTB6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/2546350:E1B03_RS04955 ^@ http://purl.uniprot.org/uniprot/A0A4P6WFM5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsL family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Membrane|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/2546350:E1B03_RS23290 ^@ http://purl.uniprot.org/uniprot/A0A4P6WT72 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. http://togogenome.org/gene/2546350:E1B03_RS18475 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Periplasm http://togogenome.org/gene/2546350:E1B03_RS22350 ^@ http://purl.uniprot.org/uniprot/A0A4P6WP70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS17875 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2546350:E1B03_RS25405 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTF3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/2546350:E1B03_RS06280 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIR5 ^@ Similarity ^@ Belongs to the UPF0386 family. http://togogenome.org/gene/2546350:E1B03_RS21045 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNM2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). http://togogenome.org/gene/2546350:E1B03_RS04760 ^@ http://purl.uniprot.org/uniprot/A0A4P6WL89 ^@ Function|||Similarity ^@ Belongs to the bacterial-type ferredoxin family. FixX subfamily.|||Could be a 3Fe-4S cluster-containing protein. http://togogenome.org/gene/2546350:E1B03_RS01475 ^@ http://purl.uniprot.org/uniprot/A0A4P6WEV6 ^@ Similarity ^@ Belongs to the Rht family. http://togogenome.org/gene/2546350:E1B03_RS16010 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS01080 ^@ http://purl.uniprot.org/uniprot/A0A4P6WGD2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS03260 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHC8 ^@ Similarity ^@ Belongs to the EcnA/EcnB lipoprotein family. http://togogenome.org/gene/2546350:E1B03_RS01020 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJ60 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. http://togogenome.org/gene/2546350:E1B03_RS06740 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMG5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane|||Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).|||The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. http://togogenome.org/gene/2546350:E1B03_RS02785 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9M9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS21290 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSD9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aldolase class II family. AraD/FucA subfamily.|||Binds 1 zinc ion per subunit.|||Homotetramer.|||Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. http://togogenome.org/gene/2546350:E1B03_RS04910 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLB6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2546350:E1B03_RS19825 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS25655 ^@ http://purl.uniprot.org/uniprot/A0A4P6WWU0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the nucleoid occlusion factor SlmA family.|||Homodimer. Interacts with FtsZ.|||Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.|||nucleoid http://togogenome.org/gene/2546350:E1B03_RS24425 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTT7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/2546350:E1B03_RS16630 ^@ http://purl.uniprot.org/uniprot/A0A4P6WP79 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiN family.|||Cell membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/2546350:E1B03_RS23460 ^@ http://purl.uniprot.org/uniprot/A0A4P6WVN4 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/2546350:E1B03_RS09260 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKF8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Dps family.|||Cytoplasm|||During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.|||Homododecamer. The 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited. http://togogenome.org/gene/2546350:E1B03_RS09610 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHQ9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2546350:E1B03_RS08545 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLG7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2546350:E1B03_RS09150 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS07130 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHL1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/2546350:E1B03_RS09930 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKR3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HspQ family.|||Cytoplasm|||Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress. http://togogenome.org/gene/2546350:E1B03_RS20030 ^@ http://purl.uniprot.org/uniprot/A0A4P6WUA3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/2546350:E1B03_RS15770 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLC0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS00965 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9J7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/2546350:E1B03_RS24950 ^@ http://purl.uniprot.org/uniprot/A0A4P6WT89 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm|||Required for resistance to DNA-damaging agents. http://togogenome.org/gene/2546350:E1B03_RS16415 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQ23 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/2546350:E1B03_RS24185 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTL8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/2546350:E1B03_RS01610 ^@ http://purl.uniprot.org/uniprot/A0A4P6WF27 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TrkH potassium transport family.|||Cell inner membrane|||Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS22480 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAP3 ^@ Similarity ^@ Belongs to the UPF0441 family. http://togogenome.org/gene/2546350:E1B03_RS06875 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJM6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS10500 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLI0 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/2546350:E1B03_RS05500 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gmhB family.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS18625 ^@ http://purl.uniprot.org/uniprot/A0A4P6WT98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS05110 ^@ http://purl.uniprot.org/uniprot/A0A4P6WFQ6 ^@ Function|||Subunit ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).|||Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/2546350:E1B03_RS24140 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSM5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2546350:E1B03_RS03390 ^@ http://purl.uniprot.org/uniprot/A0A4P6WI21 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/2546350:E1B03_RS08630 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTW5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family.|||Provides significant protection from radiation damage and may be involved in the degradation of radiation-damaged nucleotides.|||Toroid-shaped homohexamer. In the hexamer, 3 dimers assemble to form a ring-like structure surrounding a central hole. http://togogenome.org/gene/2546350:E1B03_RS04920 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRD2 ^@ Function ^@ Involved in control of the biosynthesis of leucine. http://togogenome.org/gene/2546350:E1B03_RS01570 ^@ http://purl.uniprot.org/uniprot/A0A4P6WH59 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UbiD family.|||Binds 1 prenylated FMN (prenyl-FMN) per subunit.|||Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.|||Cell membrane|||Homohexamer. http://togogenome.org/gene/2546350:E1B03_RS08690 ^@ http://purl.uniprot.org/uniprot/A0A4P6WP02 ^@ Cofactor|||Function|||Subcellular Location Annotation|||Subunit ^@ Cell inner membrane|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/2546350:E1B03_RS16225 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPV8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/2546350:E1B03_RS20040 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAJ8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/2546350:E1B03_RS11955 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLW0 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/2546350:E1B03_RS19650 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTS8 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS24825 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTZ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DcrB family.|||Cell membrane|||Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. Essential for lipoprotein maturation under conditions where membrane fluidity may be altered. http://togogenome.org/gene/2546350:E1B03_RS24945 ^@ http://purl.uniprot.org/uniprot/A0A4P6WU30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein B family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS03750 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHK7 ^@ Similarity ^@ Belongs to the UPF0307 family. http://togogenome.org/gene/2546350:E1B03_RS18405 ^@ http://purl.uniprot.org/uniprot/A0A4P6WT65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0208 family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS03540 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIX2 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/2546350:E1B03_RS07060 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMM3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/2546350:E1B03_RS09750 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJ39 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MukE family.|||Interacts, and probably forms a ternary complex, with MukF and MukB. The complex formation is stimulated by calcium or magnesium.|||Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.|||nucleoid http://togogenome.org/gene/2546350:E1B03_RS11855 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLU1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS03050 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9N4 ^@ Similarity ^@ Belongs to the YjdM family. http://togogenome.org/gene/2546350:E1B03_RS22365 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPM4 ^@ Subunit ^@ Monomer. http://togogenome.org/gene/2546350:E1B03_RS04565 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHX6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 1 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/2546350:E1B03_RS23540 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQ63 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS08970 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIQ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.|||Belongs to the AcrZ family.|||Cell membrane|||Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB. http://togogenome.org/gene/2546350:E1B03_RS01600 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIH7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.|||Binds 2 manganese ions per subunit.|||Splits dipeptides with a prolyl residue in the C-terminal position. http://togogenome.org/gene/2546350:E1B03_RS18605 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMZ6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/2546350:E1B03_RS23060 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNL0 ^@ Similarity|||Subunit ^@ Belongs to the RutC family.|||Homotrimer. http://togogenome.org/gene/2546350:E1B03_RS08315 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJZ6 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/2546350:E1B03_RS02040 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJT6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RraA family.|||Cytoplasm|||Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.|||Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB. http://togogenome.org/gene/2546350:E1B03_RS22550 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSU9 ^@ Function|||Similarity|||Subunit ^@ Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.|||Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.|||Homodimer.|||In the C-terminal section; belongs to the cytidylyltransferase family.|||In the N-terminal section; belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/2546350:E1B03_RS21190 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSC3 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2546350:E1B03_RS18325 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQ77 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2546350:E1B03_RS17315 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS18365 ^@ http://purl.uniprot.org/uniprot/A0A4P6WME8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2546350:E1B03_RS21940 ^@ http://purl.uniprot.org/uniprot/A0A4P6WN17 ^@ Function|||Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.|||Catalyzes the biosynthesis of agmatine from arginine. http://togogenome.org/gene/2546350:E1B03_RS19585 ^@ http://purl.uniprot.org/uniprot/A0A4P6WU24 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/2546350:E1B03_RS19695 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAJ2 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/2546350:E1B03_RS25750 ^@ http://purl.uniprot.org/uniprot/A0A4P6WR49 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS14420 ^@ http://purl.uniprot.org/uniprot/A0A4P6WRC9 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/2546350:E1B03_RS04610 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJR3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2546350:E1B03_RS24105 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSV3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/2546350:E1B03_RS15830 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNZ5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS24050 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTM5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2546350:E1B03_RS07225 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0014 family.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS04430 ^@ http://purl.uniprot.org/uniprot/A0A4P6WG88 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphopentomutase family.|||Binds 1 or 2 manganese ions.|||Cytoplasm|||Phosphotransfer between the C1 and C5 carbon atoms of pentose. http://togogenome.org/gene/2546350:E1B03_RS10840 ^@ http://purl.uniprot.org/uniprot/A0A4P6WME7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2546350:E1B03_RS02365 ^@ http://purl.uniprot.org/uniprot/A0A4P6WFE5 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/2546350:E1B03_RS01010 ^@ http://purl.uniprot.org/uniprot/A0A4P6WDU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS16745 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPF2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial microcompartment|||Belongs to the bacterial microcompartments protein family.|||The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low. http://togogenome.org/gene/2546350:E1B03_RS23990 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSK2 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/2546350:E1B03_RS11690 ^@ http://purl.uniprot.org/uniprot/A0A4P6WLR1 ^@ Function|||Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family.|||Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. http://togogenome.org/gene/2546350:E1B03_RS24175 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAS4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS15310 ^@ http://purl.uniprot.org/uniprot/A0A4P6WK47 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase Slt family.|||Cell outer membrane|||Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain. http://togogenome.org/gene/2546350:E1B03_RS13555 ^@ http://purl.uniprot.org/uniprot/A0A4P6WR59 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2546350:E1B03_RS03305 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJ82 ^@ Cofactor|||Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/2546350:E1B03_RS24090 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSL6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2546350:E1B03_RS01905 ^@ http://purl.uniprot.org/uniprot/A0A4P6WHA9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.|||Cell membrane|||Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system). http://togogenome.org/gene/2546350:E1B03_RS06995 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9V8 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/2546350:E1B03_RS16440 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAD1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2546350:E1B03_RS19730 ^@ http://purl.uniprot.org/uniprot/A0A4P6WNI4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2546350:E1B03_RS02675 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9M7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS16455 ^@ http://purl.uniprot.org/uniprot/A0A4P6WP51 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell inner membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS14410 ^@ http://purl.uniprot.org/uniprot/A0A4V1AA94 ^@ Function|||Similarity ^@ Belongs to the acyl coenzyme A hydrolase family.|||Catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA. http://togogenome.org/gene/2546350:E1B03_RS00740 ^@ http://purl.uniprot.org/uniprot/A0A4P6WEM4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TraA family.|||Cell inner membrane|||Membrane|||Monomer. Interacts with itself to form filaments; also interacts with TraQ.|||Secreted http://togogenome.org/gene/2546350:E1B03_RS22650 ^@ http://purl.uniprot.org/uniprot/A0A4P6WSW4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/2546350:E1B03_RS06950 ^@ http://purl.uniprot.org/uniprot/A0A4P6WMK3 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/2546350:E1B03_RS25625 ^@ http://purl.uniprot.org/uniprot/A0A4P6WR19 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/2546350:E1B03_RS25105 ^@ http://purl.uniprot.org/uniprot/A0A4P6WU56 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Cell membrane|||Membrane|||Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. http://togogenome.org/gene/2546350:E1B03_RS04800 ^@ http://purl.uniprot.org/uniprot/A0A4P6WFK0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/2546350:E1B03_RS02355 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIT9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/2546350:E1B03_RS24095 ^@ http://purl.uniprot.org/uniprot/A0A4P6WPZ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/2546350:E1B03_RS10485 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKZ9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/2546350:E1B03_RS14175 ^@ http://purl.uniprot.org/uniprot/A0A4P6WN24 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/2546350:E1B03_RS14140 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJN8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2546350:E1B03_RS03265 ^@ http://purl.uniprot.org/uniprot/A0A4P6WFU6 ^@ Similarity ^@ Belongs to the EcnA/EcnB lipoprotein family. http://togogenome.org/gene/2546350:E1B03_RS23730 ^@ http://purl.uniprot.org/uniprot/A0A4V1AAR6 ^@ Similarity ^@ Belongs to the barstar family. http://togogenome.org/gene/2546350:E1B03_RS09600 ^@ http://purl.uniprot.org/uniprot/A0A4P6WJ11 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LolA family.|||Monomer.|||Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).|||Periplasm http://togogenome.org/gene/2546350:E1B03_RS00955 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKC2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/2546350:E1B03_RS04445 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9Q9 ^@ Similarity ^@ Belongs to the Smp family. http://togogenome.org/gene/2546350:E1B03_RS23440 ^@ http://purl.uniprot.org/uniprot/A0A4P6WQ47 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/2546350:E1B03_RS17815 ^@ http://purl.uniprot.org/uniprot/A0A4P6WL90 ^@ Similarity ^@ Belongs to the elongation factor P family. http://togogenome.org/gene/2546350:E1B03_RS00485 ^@ http://purl.uniprot.org/uniprot/A0A4P6WDJ2 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Member of a two-component regulatory system. http://togogenome.org/gene/2546350:E1B03_RS19600 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTR8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HesB/IscA family.|||Binds 2 iron ions per dimer. The dimer may bind additional iron ions.|||Homodimer; may form tetramers and higher multimers.|||Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB. http://togogenome.org/gene/2546350:E1B03_RS22335 ^@ http://purl.uniprot.org/uniprot/A0A4P6WV52 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbD/TolR family.|||Cell inner membrane|||Cell membrane|||Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.|||Membrane|||The accessory proteins ExbB and ExbD seem to form a complex with TonB. http://togogenome.org/gene/2546350:E1B03_RS01450 ^@ http://purl.uniprot.org/uniprot/A0A4P6WIF2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/2546350:E1B03_RS02680 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKA9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/2546350:E1B03_RS08250 ^@ http://purl.uniprot.org/uniprot/A0A4V1A9Y1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CitD family.|||Covalent carrier of the coenzyme of citrate lyase.|||Cytoplasm|||Oligomer with a subunit composition of (alpha,beta,gamma)6. http://togogenome.org/gene/2546350:E1B03_RS24775 ^@ http://purl.uniprot.org/uniprot/A0A4P6WTY1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring. http://togogenome.org/gene/2546350:E1B03_RS16485 ^@ http://purl.uniprot.org/uniprot/A0A4P6WKL9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis.