http://togogenome.org/gene/2505979:EPZ47_RS05770 ^@ http://purl.uniprot.org/uniprot/A0A4P7PCH2 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2505979:EPZ47_RS00055 ^@ http://purl.uniprot.org/uniprot/A0A4P7P9P7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/2505979:EPZ47_RS26705 ^@ http://purl.uniprot.org/uniprot/A0A4V1CBE6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/2505979:EPZ47_RS00810 ^@ http://purl.uniprot.org/uniprot/A0A4P7PAE3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/2505979:EPZ47_RS20905 ^@ http://purl.uniprot.org/uniprot/A0A4P7PK52 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thioester dehydratase family. FabA subfamily.|||Cytoplasm|||Homodimer.|||Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. http://togogenome.org/gene/2505979:EPZ47_RS21830 ^@ http://purl.uniprot.org/uniprot/A0A4P7PK37 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmE/CycJ family.|||Cell membrane|||Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. http://togogenome.org/gene/2505979:EPZ47_RS20965 ^@ http://purl.uniprot.org/uniprot/A0A4P7PJQ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/2505979:EPZ47_RS26665 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMY6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/2505979:EPZ47_RS20990 ^@ http://purl.uniprot.org/uniprot/A0A4P7PL84 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/2505979:EPZ47_RS06540 ^@ http://purl.uniprot.org/uniprot/A0A4P7PD18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/2505979:EPZ47_RS28505 ^@ http://purl.uniprot.org/uniprot/A0A4P7PNX0 ^@ Function|||Similarity|||Subunit ^@ Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.|||Belongs to the ZapA family. Type 1 subfamily.|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/2505979:EPZ47_RS18900 ^@ http://purl.uniprot.org/uniprot/A0A4P7PJV5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/2505979:EPZ47_RS28575 ^@ http://purl.uniprot.org/uniprot/A0A4P7PND4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure. http://togogenome.org/gene/2505979:EPZ47_RS26130 ^@ http://purl.uniprot.org/uniprot/A0A4P7PM57 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/2505979:EPZ47_RS18930 ^@ http://purl.uniprot.org/uniprot/A0A4P7PIT3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2505979:EPZ47_RS26695 ^@ http://purl.uniprot.org/uniprot/A0A4P7PNK4 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/2505979:EPZ47_RS24475 ^@ http://purl.uniprot.org/uniprot/A0A4P7PLC6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/2505979:EPZ47_RS06200 ^@ http://purl.uniprot.org/uniprot/A0A4P7PE40 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/2505979:EPZ47_RS29000 ^@ http://purl.uniprot.org/uniprot/A0A4P7PNI0 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/2505979:EPZ47_RS00235 ^@ http://purl.uniprot.org/uniprot/A0A4P7PAE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0391 family.|||Cell membrane http://togogenome.org/gene/2505979:EPZ47_RS28345 ^@ http://purl.uniprot.org/uniprot/A0A4V1CBH6 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/2505979:EPZ47_RS05245 ^@ http://purl.uniprot.org/uniprot/A0A4P7PCD9 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. http://togogenome.org/gene/2505979:EPZ47_RS20320 ^@ http://purl.uniprot.org/uniprot/A0A4P7PK04 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/2505979:EPZ47_RS24565 ^@ http://purl.uniprot.org/uniprot/A0A4P7PLX1 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||Homotetramer.|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/2505979:EPZ47_RS05765 ^@ http://purl.uniprot.org/uniprot/A0A4P7PCK9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/2505979:EPZ47_RS24600 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMY7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/2505979:EPZ47_RS26675 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMD6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/2505979:EPZ47_RS12645 ^@ http://purl.uniprot.org/uniprot/A0A4P7PG83 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2505979:EPZ47_RS28120 ^@ http://purl.uniprot.org/uniprot/A0A4P7PN40 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoH subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. http://togogenome.org/gene/2505979:EPZ47_RS26655 ^@ http://purl.uniprot.org/uniprot/A0A4V1CBE5 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/2505979:EPZ47_RS02515 ^@ http://purl.uniprot.org/uniprot/A0A4P7PB70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS20345 ^@ http://purl.uniprot.org/uniprot/A0A4P7PJD8 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/2505979:EPZ47_RS05240 ^@ http://purl.uniprot.org/uniprot/A0A4P7PCB7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/2505979:EPZ47_RS24590 ^@ http://purl.uniprot.org/uniprot/A0A4P7PLI7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome b family.|||Binds 2 heme groups non-covalently.|||Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.|||Membrane|||The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein. http://togogenome.org/gene/2505979:EPZ47_RS02665 ^@ http://purl.uniprot.org/uniprot/A0A4P7PB53 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-to-5' exoribonuclease specific for small oligoribonucleotides.|||Belongs to the oligoribonuclease family.|||Cytoplasm http://togogenome.org/gene/2505979:EPZ47_RS18235 ^@ http://purl.uniprot.org/uniprot/A0A4V1CAZ0 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/2505979:EPZ47_RS23005 ^@ http://purl.uniprot.org/uniprot/A0A4P7PM70 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/2505979:EPZ47_RS18915 ^@ http://purl.uniprot.org/uniprot/A0A4P7PJC9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/2505979:EPZ47_RS25130 ^@ http://purl.uniprot.org/uniprot/A0A4P7PLQ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/2505979:EPZ47_RS26660 ^@ http://purl.uniprot.org/uniprot/A0A4P7PN29 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/2505979:EPZ47_RS03015 ^@ http://purl.uniprot.org/uniprot/A0A4P7PCC2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/2505979:EPZ47_RS21800 ^@ http://purl.uniprot.org/uniprot/A0A4P7PL86 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatB family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/2505979:EPZ47_RS01945 ^@ http://purl.uniprot.org/uniprot/A0A4P7PAR9 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). http://togogenome.org/gene/2505979:EPZ47_RS07460 ^@ http://purl.uniprot.org/uniprot/A0A4P7PDE1 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. http://togogenome.org/gene/2505979:EPZ47_RS06470 ^@ http://purl.uniprot.org/uniprot/A0A4P7PE85 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/2505979:EPZ47_RS05280 ^@ http://purl.uniprot.org/uniprot/A0A4P7PCH4 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/2505979:EPZ47_RS18920 ^@ http://purl.uniprot.org/uniprot/A0A4P7PJ43 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/2505979:EPZ47_RS10355 ^@ http://purl.uniprot.org/uniprot/A0A4P7PEP3 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit A family. http://togogenome.org/gene/2505979:EPZ47_RS09570 ^@ http://purl.uniprot.org/uniprot/A0A4P7PFM2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.|||Cytoplasm http://togogenome.org/gene/2505979:EPZ47_RS18265 ^@ http://purl.uniprot.org/uniprot/A0A4P7PIH7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2505979:EPZ47_RS18110 ^@ http://purl.uniprot.org/uniprot/A0A4P7PIF3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrcB (TC 9.B.71) family.|||Cell membrane|||Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS23385 ^@ http://purl.uniprot.org/uniprot/A0A4P7PKW1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2505979:EPZ47_RS26710 ^@ http://purl.uniprot.org/uniprot/A0A4P7PN38 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/2505979:EPZ47_RS29830 ^@ http://purl.uniprot.org/uniprot/A0A4P7PNX6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/2505979:EPZ47_RS26840 ^@ http://purl.uniprot.org/uniprot/A0A4P7PML3 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/2505979:EPZ47_RS26670 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMI0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/2505979:EPZ47_RS20520 ^@ http://purl.uniprot.org/uniprot/A0A4P7PK42 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/2505979:EPZ47_RS05855 ^@ http://purl.uniprot.org/uniprot/A0A4P7PCK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/2505979:EPZ47_RS04115 ^@ http://purl.uniprot.org/uniprot/A0A4P7PBZ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/2505979:EPZ47_RS09305 ^@ http://purl.uniprot.org/uniprot/A0A4P7PE74 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/2505979:EPZ47_RS26650 ^@ http://purl.uniprot.org/uniprot/A0A4P7PNY5 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/2505979:EPZ47_RS26745 ^@ http://purl.uniprot.org/uniprot/A0A4P7PNL0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2505979:EPZ47_RS21815 ^@ http://purl.uniprot.org/uniprot/A0A4P7PKR1 ^@ Function|||Similarity ^@ Belongs to the CcmH/CycL/Ccl2/NrfF family.|||Possible subunit of a heme lyase. http://togogenome.org/gene/2505979:EPZ47_RS08380 ^@ http://purl.uniprot.org/uniprot/A0A4P7PDY1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/2505979:EPZ47_RS09130 ^@ http://purl.uniprot.org/uniprot/A0A4P7PE37 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscS (TC 1.A.23) family.|||Cell inner membrane|||Homoheptamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions. http://togogenome.org/gene/2505979:EPZ47_RS24510 ^@ http://purl.uniprot.org/uniprot/A0A4P7PLF6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS21160 ^@ http://purl.uniprot.org/uniprot/A0A4P7PKA6 ^@ Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.|||Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue. http://togogenome.org/gene/2505979:EPZ47_RS26735 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMH0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/2505979:EPZ47_RS12350 ^@ http://purl.uniprot.org/uniprot/A0A4P7PFM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS07290 ^@ http://purl.uniprot.org/uniprot/A0A4P7PD75 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2505979:EPZ47_RS08110 ^@ http://purl.uniprot.org/uniprot/A0A4P7PEZ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sigma-70 factor family. FliA subfamily.|||Cytoplasm|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes. http://togogenome.org/gene/2505979:EPZ47_RS26790 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMK7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/2505979:EPZ47_RS23515 ^@ http://purl.uniprot.org/uniprot/A0A4P7PKV8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/2505979:EPZ47_RS02705 ^@ http://purl.uniprot.org/uniprot/A0A4P7PBJ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/2505979:EPZ47_RS05420 ^@ http://purl.uniprot.org/uniprot/A0A4P7PDJ6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/2505979:EPZ47_RS23135 ^@ http://purl.uniprot.org/uniprot/A0A4P7PKR6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/2505979:EPZ47_RS20590 ^@ http://purl.uniprot.org/uniprot/A0A4P7PJQ0 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/2505979:EPZ47_RS08715 ^@ http://purl.uniprot.org/uniprot/A0A4P7PE13 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/2505979:EPZ47_RS28130 ^@ http://purl.uniprot.org/uniprot/A0A4P7PP90 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring. http://togogenome.org/gene/2505979:EPZ47_RS08320 ^@ http://purl.uniprot.org/uniprot/A0A4V1CAF4 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/2505979:EPZ47_RS29030 ^@ http://purl.uniprot.org/uniprot/A0A4P7PP24 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/2505979:EPZ47_RS08735 ^@ http://purl.uniprot.org/uniprot/A0A4P7PF78 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2505979:EPZ47_RS09405 ^@ http://purl.uniprot.org/uniprot/A0A4P7PE94 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Binds 1 copper ion per subunit, denoted as copper B.|||Binds 2 heme groups per subunit, denoted as high- and low-spin.|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS29900 ^@ http://purl.uniprot.org/uniprot/A0A4V1CBK6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/2505979:EPZ47_RS28955 ^@ http://purl.uniprot.org/uniprot/A0A4P7PNK8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/2505979:EPZ47_RS05410 ^@ http://purl.uniprot.org/uniprot/A0A4P7PCC4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/2505979:EPZ47_RS21010 ^@ http://purl.uniprot.org/uniprot/A0A4P7PJS7 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/2505979:EPZ47_RS20970 ^@ http://purl.uniprot.org/uniprot/A0A4P7PJV7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/2505979:EPZ47_RS29505 ^@ http://purl.uniprot.org/uniprot/A0A4P7PNT6 ^@ Similarity ^@ Belongs to the class-II fumarase/aspartase family. Aspartase subfamily. http://togogenome.org/gene/2505979:EPZ47_RS07545 ^@ http://purl.uniprot.org/uniprot/A0A4P7PDI7 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/2505979:EPZ47_RS21545 ^@ http://purl.uniprot.org/uniprot/A0A4P7PK18 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/2505979:EPZ47_RS28990 ^@ http://purl.uniprot.org/uniprot/A0A4P7PNG2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/2505979:EPZ47_RS27490 ^@ http://purl.uniprot.org/uniprot/A0A4V1CBG0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2505979:EPZ47_RS02670 ^@ http://purl.uniprot.org/uniprot/A0A4P7PB63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS26830 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMN1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/2505979:EPZ47_RS24595 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMI2 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Rieske iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster per subunit.|||Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.|||Membrane|||The Rieske protein is a high potential 2Fe-2S protein.|||The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein. http://togogenome.org/gene/2505979:EPZ47_RS24200 ^@ http://purl.uniprot.org/uniprot/A0A4P7PLA2 ^@ Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/2505979:EPZ47_RS29410 ^@ http://purl.uniprot.org/uniprot/A0A4P7PNW8 ^@ Function ^@ This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited. http://togogenome.org/gene/2505979:EPZ47_RS04120 ^@ http://purl.uniprot.org/uniprot/A0A4P7PBV4 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/2505979:EPZ47_RS26700 ^@ http://purl.uniprot.org/uniprot/A0A4P7PNZ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/2505979:EPZ47_RS09435 ^@ http://purl.uniprot.org/uniprot/A0A4P7PEF9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfur carrier protein TusA family.|||Cytoplasm|||Sulfur carrier protein which probably makes part of a sulfur-relay system. http://togogenome.org/gene/2505979:EPZ47_RS26855 ^@ http://purl.uniprot.org/uniprot/A0A4P7PP16 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/2505979:EPZ47_RS23485 ^@ http://purl.uniprot.org/uniprot/A0A4P7PLZ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Pal lipoprotein family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/2505979:EPZ47_RS23510 ^@ http://purl.uniprot.org/uniprot/A0A4P7PKX9 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/2505979:EPZ47_RS09030 ^@ http://purl.uniprot.org/uniprot/A0A4P7PE19 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2505979:EPZ47_RS19010 ^@ http://purl.uniprot.org/uniprot/A0A4V1CB04 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/2505979:EPZ47_RS04125 ^@ http://purl.uniprot.org/uniprot/A0A4P7PBU0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/2505979:EPZ47_RS26090 ^@ http://purl.uniprot.org/uniprot/A0A4P7PN89 ^@ Similarity ^@ Belongs to the UPF0250 family. http://togogenome.org/gene/2505979:EPZ47_RS08060 ^@ http://purl.uniprot.org/uniprot/A0A4P7PEY6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliN/MopA/SpaO family.|||Cell membrane|||FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS05865 ^@ http://purl.uniprot.org/uniprot/A0A4P7PCM5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsB family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/2505979:EPZ47_RS23520 ^@ http://purl.uniprot.org/uniprot/A0A4P7PL13 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/2505979:EPZ47_RS29435 ^@ http://purl.uniprot.org/uniprot/A0A4V1CBJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/2505979:EPZ47_RS26800 ^@ http://purl.uniprot.org/uniprot/A0A4P7PP11 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/2505979:EPZ47_RS08000 ^@ http://purl.uniprot.org/uniprot/A0A4P7PDJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/2505979:EPZ47_RS03235 ^@ http://purl.uniprot.org/uniprot/A0A4P7PCI1 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/2505979:EPZ47_RS28185 ^@ http://purl.uniprot.org/uniprot/A0A4P7PPL9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/2505979:EPZ47_RS21835 ^@ http://purl.uniprot.org/uniprot/A0A4P7PKA0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmD/CycX/HelD family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/2505979:EPZ47_RS25530 ^@ http://purl.uniprot.org/uniprot/A0A4P7PLV5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/2505979:EPZ47_RS23320 ^@ http://purl.uniprot.org/uniprot/A0A4V1CB83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS18740 ^@ http://purl.uniprot.org/uniprot/A0A4P7PJD8 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/2505979:EPZ47_RS02095 ^@ http://purl.uniprot.org/uniprot/A0A4P7PAV8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2505979:EPZ47_RS21455 ^@ http://purl.uniprot.org/uniprot/A0A4P7PQ02 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/2505979:EPZ47_RS25855 ^@ http://purl.uniprot.org/uniprot/A0A4P7PLZ2 ^@ Similarity ^@ Belongs to the outer membrane porin (Opr) (TC 1.B.25) family. http://togogenome.org/gene/2505979:EPZ47_RS26775 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMF0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2505979:EPZ47_RS18255 ^@ http://purl.uniprot.org/uniprot/A0A4P7PIH9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2505979:EPZ47_RS26720 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMI7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/2505979:EPZ47_RS26625 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMC7 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/2505979:EPZ47_RS26940 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMK1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HesB/IscA family.|||Binds 1 iron-sulfur cluster per subunit.|||Homodimer.|||Required for insertion of 4Fe-4S clusters for at least IspG. http://togogenome.org/gene/2505979:EPZ47_RS08180 ^@ http://purl.uniprot.org/uniprot/A0A4P7PDM3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmB/CycW/HelB family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/2505979:EPZ47_RS09195 ^@ http://purl.uniprot.org/uniprot/A0A4P7PE98 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ribosome modulation factor family.|||Cytoplasm|||During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes). http://togogenome.org/gene/2505979:EPZ47_RS12600 ^@ http://purl.uniprot.org/uniprot/A0A4P7PG00 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/2505979:EPZ47_RS28000 ^@ http://purl.uniprot.org/uniprot/A0A4P7PN24 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/2505979:EPZ47_RS26380 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMA5 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/2505979:EPZ47_RS18145 ^@ http://purl.uniprot.org/uniprot/A0A4P7PIE8 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/2505979:EPZ47_RS26020 ^@ http://purl.uniprot.org/uniprot/A0A4P7PM90 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/2505979:EPZ47_RS26715 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMZ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/2505979:EPZ47_RS29890 ^@ http://purl.uniprot.org/uniprot/A0A4P7PQ96 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/2505979:EPZ47_RS05805 ^@ http://purl.uniprot.org/uniprot/A0A4P7PCJ9 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/2505979:EPZ47_RS28700 ^@ http://purl.uniprot.org/uniprot/A0A4P7PPH7 ^@ Similarity ^@ Belongs to the Rsd/AlgQ family. http://togogenome.org/gene/2505979:EPZ47_RS26685 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMG2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2505979:EPZ47_RS26420 ^@ http://purl.uniprot.org/uniprot/A0A4P7PM89 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/2505979:EPZ47_RS07275 ^@ http://purl.uniprot.org/uniprot/A0A4V1CAD4 ^@ Function|||Similarity ^@ An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.|||Belongs to the SdhE FAD assembly factor family. http://togogenome.org/gene/2505979:EPZ47_RS09095 ^@ http://purl.uniprot.org/uniprot/A0A4P7PE35 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/2505979:EPZ47_RS21825 ^@ http://purl.uniprot.org/uniprot/A0A4P7PK58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS04105 ^@ http://purl.uniprot.org/uniprot/A0A4V1CA74 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/2505979:EPZ47_RS05860 ^@ http://purl.uniprot.org/uniprot/A0A4P7PCK2 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/2505979:EPZ47_RS22625 ^@ http://purl.uniprot.org/uniprot/A0A4P7PKM5 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TtcA family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.|||Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.|||Cytoplasm|||Homodimer.|||The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster. http://togogenome.org/gene/2505979:EPZ47_RS29390 ^@ http://purl.uniprot.org/uniprot/A0A4P7PPC8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit.|||Cytoplasm http://togogenome.org/gene/2505979:EPZ47_RS18150 ^@ http://purl.uniprot.org/uniprot/A0A4P7PIG2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/2505979:EPZ47_RS29860 ^@ http://purl.uniprot.org/uniprot/A0A4P7PPF3 ^@ Function|||Similarity ^@ Belongs to the ParB family.|||Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication. http://togogenome.org/gene/2505979:EPZ47_RS18220 ^@ http://purl.uniprot.org/uniprot/A0A4P7PIN0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2505979:EPZ47_RS22815 ^@ http://purl.uniprot.org/uniprot/A0A4P7PL70 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/2505979:EPZ47_RS03120 ^@ http://purl.uniprot.org/uniprot/A0A4P7PBC7 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/2505979:EPZ47_RS28960 ^@ http://purl.uniprot.org/uniprot/A0A4P7PPM3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/2505979:EPZ47_RS29495 ^@ http://purl.uniprot.org/uniprot/A0A4P7PPE1 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/2505979:EPZ47_RS09135 ^@ http://purl.uniprot.org/uniprot/A0A4P7PE34 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2505979:EPZ47_RS26680 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMK6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/2505979:EPZ47_RS07295 ^@ http://purl.uniprot.org/uniprot/A0A4P7PD66 ^@ Similarity ^@ Belongs to the RseA family. http://togogenome.org/gene/2505979:EPZ47_RS29465 ^@ http://purl.uniprot.org/uniprot/A0A4P7PNR1 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/2505979:EPZ47_RS02765 ^@ http://purl.uniprot.org/uniprot/A0A4V1CA50 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/2505979:EPZ47_RS27260 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMT9 ^@ Similarity ^@ Belongs to the UPF0057 (PMP3) family. http://togogenome.org/gene/2505979:EPZ47_RS29815 ^@ http://purl.uniprot.org/uniprot/A0A4P7PNZ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/2505979:EPZ47_RS26475 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMH2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.|||Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers. http://togogenome.org/gene/2505979:EPZ47_RS03210 ^@ http://purl.uniprot.org/uniprot/A0A4P7PBD9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/2505979:EPZ47_RS21805 ^@ http://purl.uniprot.org/uniprot/A0A4P7PLL9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/2505979:EPZ47_RS08010 ^@ http://purl.uniprot.org/uniprot/A0A4P7PEX9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Cell inner membrane|||FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS25125 ^@ http://purl.uniprot.org/uniprot/A0A4P7PM61 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2505979:EPZ47_RS27230 ^@ http://purl.uniprot.org/uniprot/A0A4P7PPC6 ^@ Function|||Similarity ^@ Belongs to the PqqA family.|||Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide. http://togogenome.org/gene/2505979:EPZ47_RS21930 ^@ http://purl.uniprot.org/uniprot/A0A4P7PLN6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2505979:EPZ47_RS04415 ^@ http://purl.uniprot.org/uniprot/A0A4P7PBW8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Cell inner membrane|||Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS19435 ^@ http://purl.uniprot.org/uniprot/A0A4P7PIZ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2505979:EPZ47_RS02730 ^@ http://purl.uniprot.org/uniprot/A0A4P7PB57 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/2505979:EPZ47_RS09175 ^@ http://purl.uniprot.org/uniprot/A0A4P7PEL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Cell membrane|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS21005 ^@ http://purl.uniprot.org/uniprot/A0A4P7PK76 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome b560 family.|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/2505979:EPZ47_RS28580 ^@ http://purl.uniprot.org/uniprot/A0A4P7PN86 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/2505979:EPZ47_RS27130 ^@ http://purl.uniprot.org/uniprot/A0A4P7PN54 ^@ Similarity ^@ Belongs to the UPF0229 family. http://togogenome.org/gene/2505979:EPZ47_RS05890 ^@ http://purl.uniprot.org/uniprot/A0A4V1CAA8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). http://togogenome.org/gene/2505979:EPZ47_RS08755 ^@ http://purl.uniprot.org/uniprot/A0A4P7PDX5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2505979:EPZ47_RS26760 ^@ http://purl.uniprot.org/uniprot/A0A4P7PN46 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/2505979:EPZ47_RS05185 ^@ http://purl.uniprot.org/uniprot/A0A4P7PCB1 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/2505979:EPZ47_RS04405 ^@ http://purl.uniprot.org/uniprot/A0A4P7PC09 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/2505979:EPZ47_RS26690 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMJ2 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2505979:EPZ47_RS18225 ^@ http://purl.uniprot.org/uniprot/A0A4P7PJK3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2505979:EPZ47_RS24605 ^@ http://purl.uniprot.org/uniprot/A0A4V1CBA7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/2505979:EPZ47_RS26820 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMK3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/2505979:EPZ47_RS01585 ^@ http://purl.uniprot.org/uniprot/A0A4P7PBR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/2505979:EPZ47_RS09515 ^@ http://purl.uniprot.org/uniprot/A0A4P7PFI2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/2505979:EPZ47_RS24250 ^@ http://purl.uniprot.org/uniprot/A0A4P7PLB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS18140 ^@ http://purl.uniprot.org/uniprot/A0A4P7PIS3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/2505979:EPZ47_RS04560 ^@ http://purl.uniprot.org/uniprot/A0A4P7PC31 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2505979:EPZ47_RS02780 ^@ http://purl.uniprot.org/uniprot/A0A4P7PB68 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/2505979:EPZ47_RS04215 ^@ http://purl.uniprot.org/uniprot/A0A4P7PD60 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/2505979:EPZ47_RS05205 ^@ http://purl.uniprot.org/uniprot/A0A4P7PC86 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/2505979:EPZ47_RS25500 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMG4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/2505979:EPZ47_RS26725 ^@ http://purl.uniprot.org/uniprot/A0A4P7PME4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2505979:EPZ47_RS01995 ^@ http://purl.uniprot.org/uniprot/A0A4P7PAS9 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/2505979:EPZ47_RS10350 ^@ http://purl.uniprot.org/uniprot/A0A4P7PEQ6 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/2505979:EPZ47_RS01090 ^@ http://purl.uniprot.org/uniprot/A0A4P7PAH7 ^@ Function|||Similarity ^@ Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.|||Belongs to the Nudix hydrolase family. RppH subfamily. http://togogenome.org/gene/2505979:EPZ47_RS07350 ^@ http://purl.uniprot.org/uniprot/A0A4P7PDC4 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/2505979:EPZ47_RS21790 ^@ http://purl.uniprot.org/uniprot/A0A4P7PK31 ^@ Similarity ^@ Belongs to the outer membrane porin (Opr) (TC 1.B.25) family. http://togogenome.org/gene/2505979:EPZ47_RS23235 ^@ http://purl.uniprot.org/uniprot/A0A4P7PKT4 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. http://togogenome.org/gene/2505979:EPZ47_RS20500 ^@ http://purl.uniprot.org/uniprot/A0A4P7PJN4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/2505979:EPZ47_RS19430 ^@ http://purl.uniprot.org/uniprot/A0A4P7PJ58 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2505979:EPZ47_RS05690 ^@ http://purl.uniprot.org/uniprot/A0A4V1CAA4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2505979:EPZ47_RS25670 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMI8 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/2505979:EPZ47_RS26730 ^@ http://purl.uniprot.org/uniprot/A0A4P7PML6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/2505979:EPZ47_RS04600 ^@ http://purl.uniprot.org/uniprot/A0A4P7PC21 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PAPS reductase family. CysD subfamily.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/2505979:EPZ47_RS29845 ^@ http://purl.uniprot.org/uniprot/A0A4P7PQU3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS28820 ^@ http://purl.uniprot.org/uniprot/A0A4P7PP27 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/2505979:EPZ47_RS04400 ^@ http://purl.uniprot.org/uniprot/A0A4P7PBY1 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/2505979:EPZ47_RS01605 ^@ http://purl.uniprot.org/uniprot/A0A4P7PAT4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/2505979:EPZ47_RS05260 ^@ http://purl.uniprot.org/uniprot/A0A4P7PDG6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/2505979:EPZ47_RS28095 ^@ http://purl.uniprot.org/uniprot/A0A4P7PN53 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/2505979:EPZ47_RS25400 ^@ http://purl.uniprot.org/uniprot/A0A4P7PME6 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/2505979:EPZ47_RS26950 ^@ http://purl.uniprot.org/uniprot/A0A4P7PNP0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HemJ family.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS21540 ^@ http://purl.uniprot.org/uniprot/A0A4P7PKG5 ^@ Function|||Similarity|||Subunit ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily.|||Interacts with MinC and FtsZ. http://togogenome.org/gene/2505979:EPZ47_RS23140 ^@ http://purl.uniprot.org/uniprot/A0A4P7PKP9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/2505979:EPZ47_RS27150 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMN3 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/2505979:EPZ47_RS28335 ^@ http://purl.uniprot.org/uniprot/A0A4P7PPC7 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/2505979:EPZ47_RS18940 ^@ http://purl.uniprot.org/uniprot/A0A4P7PIS2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2505979:EPZ47_RS25525 ^@ http://purl.uniprot.org/uniprot/A0A4P7PM05 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/2505979:EPZ47_RS29380 ^@ http://purl.uniprot.org/uniprot/A0A4P7PQI4 ^@ Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/2505979:EPZ47_RS05165 ^@ http://purl.uniprot.org/uniprot/A0A4P7PDL6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane|||Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).|||The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. http://togogenome.org/gene/2505979:EPZ47_RS28010 ^@ http://purl.uniprot.org/uniprot/A0A4P7PP71 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/2505979:EPZ47_RS01300 ^@ http://purl.uniprot.org/uniprot/A0A4P7PAG6 ^@ Cofactor|||Similarity ^@ Belongs to the RimK family.|||Binds 2 magnesium or manganese ions per subunit. http://togogenome.org/gene/2505979:EPZ47_RS23525 ^@ http://purl.uniprot.org/uniprot/A0A4P7PKW5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/2505979:EPZ47_RS00010 ^@ http://purl.uniprot.org/uniprot/A0A4P7P9M4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/2505979:EPZ47_RS04625 ^@ http://purl.uniprot.org/uniprot/A0A4P7PD54 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/2505979:EPZ47_RS26815 ^@ http://purl.uniprot.org/uniprot/A0A4P7PN12 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/2505979:EPZ47_RS18280 ^@ http://purl.uniprot.org/uniprot/A0A4P7PJU2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2505979:EPZ47_RS26240 ^@ http://purl.uniprot.org/uniprot/A0A4P7PNB9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/2505979:EPZ47_RS24540 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMH5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/2505979:EPZ47_RS27935 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMX8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MdcC family.|||Covalently binds the prosthetic group of malonate decarboxylase.|||Cytoplasm|||Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism. http://togogenome.org/gene/2505979:EPZ47_RS21095 ^@ http://purl.uniprot.org/uniprot/A0A4V1CB42 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2505979:EPZ47_RS08255 ^@ http://purl.uniprot.org/uniprot/A0A4P7PEV9 ^@ Similarity ^@ Belongs to the UPF0270 family. http://togogenome.org/gene/2505979:EPZ47_RS20525 ^@ http://purl.uniprot.org/uniprot/A0A4P7PJW2 ^@ Function|||Similarity ^@ Belongs to the DUF177 domain family.|||Plays a role in synthesis, processing and/or stability of 23S rRNA. http://togogenome.org/gene/2505979:EPZ47_RS03205 ^@ http://purl.uniprot.org/uniprot/A0A4P7PBK6 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/2505979:EPZ47_RS24780 ^@ http://purl.uniprot.org/uniprot/A0A4P7PLH4 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/2505979:EPZ47_RS09320 ^@ http://purl.uniprot.org/uniprot/A0A4P7PFH1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2505979:EPZ47_RS26845 ^@ http://purl.uniprot.org/uniprot/A0A4P7PNN2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2505979:EPZ47_RS21980 ^@ http://purl.uniprot.org/uniprot/A0A4P7PLP4 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS18250 ^@ http://purl.uniprot.org/uniprot/A0A4P7PIG7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/2505979:EPZ47_RS26765 ^@ http://purl.uniprot.org/uniprot/A0A4P7PN03 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/2505979:EPZ47_RS21795 ^@ http://purl.uniprot.org/uniprot/A0A4P7PK94 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/2505979:EPZ47_RS25255 ^@ http://purl.uniprot.org/uniprot/A0A4P7PLU5 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/2505979:EPZ47_RS06290 ^@ http://purl.uniprot.org/uniprot/A0A4P7PCU0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2505979:EPZ47_RS09485 ^@ http://purl.uniprot.org/uniprot/A0A4P7PEG6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. Thiolase family.|||Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.|||Cytoplasm|||Heterotetramer of two alpha chains (FadB) and two beta chains (FadA). http://togogenome.org/gene/2505979:EPZ47_RS03140 ^@ http://purl.uniprot.org/uniprot/A0A4V1CA57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS00090 ^@ http://purl.uniprot.org/uniprot/A0A4P7P9R8 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/2505979:EPZ47_RS09880 ^@ http://purl.uniprot.org/uniprot/A0A4P7PEG0 ^@ Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/2505979:EPZ47_RS00635 ^@ http://purl.uniprot.org/uniprot/A0A4P7PA33 ^@ Function ^@ The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/2505979:EPZ47_RS25040 ^@ http://purl.uniprot.org/uniprot/A0A4P7PM92 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein S18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2505979:EPZ47_RS07785 ^@ http://purl.uniprot.org/uniprot/A0A4P7PDJ4 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/2505979:EPZ47_RS12365 ^@ http://purl.uniprot.org/uniprot/A0A4P7PFN6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2505979:EPZ47_RS23215 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMA1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/2505979:EPZ47_RS26755 ^@ http://purl.uniprot.org/uniprot/A0A4V1CBE7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/2505979:EPZ47_RS29025 ^@ http://purl.uniprot.org/uniprot/A0A4P7PP65 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/2505979:EPZ47_RS26770 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMJ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/2505979:EPZ47_RS27745 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMY0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.|||One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/2505979:EPZ47_RS20505 ^@ http://purl.uniprot.org/uniprot/A0A4P7PKL8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/2505979:EPZ47_RS24315 ^@ http://purl.uniprot.org/uniprot/A0A4P7PL98 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/2505979:EPZ47_RS26125 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMA8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/2505979:EPZ47_RS23725 ^@ http://purl.uniprot.org/uniprot/A0A4P7PL02 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Catalyzes the reversible hydration of fumarate to (S)-malate.|||Homodimer. http://togogenome.org/gene/2505979:EPZ47_RS26835 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMJ1 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/2505979:EPZ47_RS25565 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0114 family.|||Cell membrane|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS03175 ^@ http://purl.uniprot.org/uniprot/A0A4P7PBC8 ^@ Similarity ^@ Belongs to the transcriptional regulatory Fis family. http://togogenome.org/gene/2505979:EPZ47_RS22320 ^@ http://purl.uniprot.org/uniprot/A0A4P7PLV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS05435 ^@ http://purl.uniprot.org/uniprot/A0A4P7PCR2 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/2505979:EPZ47_RS11250 ^@ http://purl.uniprot.org/uniprot/A0A4P7PF99 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2505979:EPZ47_RS11795 ^@ http://purl.uniprot.org/uniprot/A0A4P7PFJ5 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/2505979:EPZ47_RS27165 ^@ http://purl.uniprot.org/uniprot/A0A4P7PP61 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/2505979:EPZ47_RS29820 ^@ http://purl.uniprot.org/uniprot/A0A4P7PNW3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/2505979:EPZ47_RS05405 ^@ http://purl.uniprot.org/uniprot/A0A4P7PCF8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/2505979:EPZ47_RS04130 ^@ http://purl.uniprot.org/uniprot/A0A4P7PBX1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/2505979:EPZ47_RS03000 ^@ http://purl.uniprot.org/uniprot/A0A4P7PBF2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease beta subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/2505979:EPZ47_RS26785 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMH8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/2505979:EPZ47_RS05210 ^@ http://purl.uniprot.org/uniprot/A0A4P7PDF6 ^@ Function|||Similarity ^@ A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.|||Belongs to the NifU family. http://togogenome.org/gene/2505979:EPZ47_RS01145 ^@ http://purl.uniprot.org/uniprot/A0A4P7PAC0 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/2505979:EPZ47_RS09865 ^@ http://purl.uniprot.org/uniprot/A0A4V1CAI3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/2505979:EPZ47_RS26750 ^@ http://purl.uniprot.org/uniprot/A0A4P7PP00 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/2505979:EPZ47_RS08410 ^@ http://purl.uniprot.org/uniprot/A0A4P7PDR9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family.|||Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. http://togogenome.org/gene/2505979:EPZ47_RS09315 ^@ http://purl.uniprot.org/uniprot/A0A4P7PFE8 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/2505979:EPZ47_RS29035 ^@ http://purl.uniprot.org/uniprot/A0A4P7PNL1 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/2505979:EPZ47_RS05915 ^@ http://purl.uniprot.org/uniprot/A0A4P7PCN4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoS subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. http://togogenome.org/gene/2505979:EPZ47_RS21000 ^@ http://purl.uniprot.org/uniprot/A0A4P7PKD0 ^@ Cofactor|||Function|||Subcellular Location Annotation|||Subunit ^@ Cell inner membrane|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/2505979:EPZ47_RS00350 ^@ http://purl.uniprot.org/uniprot/A0A4P7P9Y4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family. TsaC subfamily.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. http://togogenome.org/gene/2505979:EPZ47_RS05760 ^@ http://purl.uniprot.org/uniprot/A0A4P7PCI6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/2505979:EPZ47_RS24580 ^@ http://purl.uniprot.org/uniprot/A0A4P7PLJ0 ^@ Similarity ^@ Belongs to the GST superfamily. HSP26 family. http://togogenome.org/gene/2505979:EPZ47_RS12860 ^@ http://purl.uniprot.org/uniprot/A0A4P7PGC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP G family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS01660 ^@ http://purl.uniprot.org/uniprot/A0A4P7PAM5 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. http://togogenome.org/gene/2505979:EPZ47_RS19640 ^@ http://purl.uniprot.org/uniprot/A0A4V1CB15 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/2505979:EPZ47_RS08165 ^@ http://purl.uniprot.org/uniprot/A0A4V1CAF1 ^@ Similarity ^@ Belongs to the type III secretion exporter family. http://togogenome.org/gene/2505979:EPZ47_RS24880 ^@ http://purl.uniprot.org/uniprot/A0A4P7PLM3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/2505979:EPZ47_RS05230 ^@ http://purl.uniprot.org/uniprot/A0A4P7PCG3 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/2505979:EPZ47_RS05920 ^@ http://purl.uniprot.org/uniprot/A0A4P7PCJ8 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/2505979:EPZ47_RS02770 ^@ http://purl.uniprot.org/uniprot/A0A4P7PBK8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/2505979:EPZ47_RS00650 ^@ http://purl.uniprot.org/uniprot/A0A4V1CA11 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2505979:EPZ47_RS29485 ^@ http://purl.uniprot.org/uniprot/A0A4P7PQK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS14180 ^@ http://purl.uniprot.org/uniprot/A0A4P7PP49 ^@ Function|||Similarity ^@ Belongs to the PqqA family.|||Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide. http://togogenome.org/gene/2505979:EPZ47_RS04895 ^@ http://purl.uniprot.org/uniprot/A0A4P7PDH1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase bacterial subunit 4 family.|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS07905 ^@ http://purl.uniprot.org/uniprot/A0A4P7PEQ3 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/2505979:EPZ47_RS26780 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMM0 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||Methylated by PrmB.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/2505979:EPZ47_RS26460 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMU5 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). http://togogenome.org/gene/2505979:EPZ47_RS21840 ^@ http://purl.uniprot.org/uniprot/A0A4P7PK40 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmC/CycZ/HelC family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/2505979:EPZ47_RS28105 ^@ http://purl.uniprot.org/uniprot/A0A4P7PN01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0382 family.|||Membrane http://togogenome.org/gene/2505979:EPZ47_RS21820 ^@ http://purl.uniprot.org/uniprot/A0A4P7PKL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbE subfamily.|||Cell inner membrane http://togogenome.org/gene/2505979:EPZ47_RS04225 ^@ http://purl.uniprot.org/uniprot/A0A4P7PC71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2505979:EPZ47_RS26805 ^@ http://purl.uniprot.org/uniprot/A0A4V1CBE8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/2505979:EPZ47_RS26740 ^@ http://purl.uniprot.org/uniprot/A0A4P7PMJ9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/2505979:EPZ47_RS09695 ^@ http://purl.uniprot.org/uniprot/A0A4P7PEK4 ^@ Similarity ^@ Belongs to the FrmR/RcnR family.