http://togogenome.org/gene/2492438:G6N19_RS09025 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNY3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrgA family.|||Cell membrane|||Involved in cell division. http://togogenome.org/gene/2492438:G6N19_RS07295 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKG5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS06550 ^@ http://purl.uniprot.org/uniprot/A0A7I7JK34 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/2492438:G6N19_RS15180 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQ03 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Bifunctional enzyme that catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2-dependent reduction of dehydro-F420-0 to form F420-0.|||Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.|||In the N-terminal section; belongs to the CofE family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monovalent cation. The ion could be potassium. http://togogenome.org/gene/2492438:G6N19_RS07370 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMG5 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/2492438:G6N19_RS20650 ^@ http://purl.uniprot.org/uniprot/A0A7I7JVF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CbxX/CfxQ family.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS01590 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJU7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/2492438:G6N19_RS18860 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS10815 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPF1 ^@ Similarity ^@ Belongs to the MmpS family. http://togogenome.org/gene/2492438:G6N19_RS13635 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQP8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2492438:G6N19_RS10420 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS00605 ^@ http://purl.uniprot.org/uniprot/A0A7I7JH30 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/2492438:G6N19_RS01960 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS04710 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJC8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/2492438:G6N19_RS18015 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS11 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS10085 ^@ http://purl.uniprot.org/uniprot/A0A7I7JM00 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems.|||Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/2492438:G6N19_RS06780 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMR5 ^@ Cofactor ^@ Can also use Mn(2+) ion. http://togogenome.org/gene/2492438:G6N19_RS20200 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUI5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M15D family.|||Binds 1 zinc ion per subunit.|||Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. http://togogenome.org/gene/2492438:G6N19_RS12690 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQ66 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2492438:G6N19_RS10605 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/2492438:G6N19_RS00280 ^@ http://purl.uniprot.org/uniprot/A0A7I7JI25 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/2492438:G6N19_RS03770 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIC6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS14230 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPG7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-C family. DnaE2 subfamily.|||Cytoplasm|||DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. http://togogenome.org/gene/2492438:G6N19_RS08605 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLI8 ^@ Function|||Similarity ^@ Belongs to the UPF0677 family.|||Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. http://togogenome.org/gene/2492438:G6N19_RS02795 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJF7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2492438:G6N19_RS01310 ^@ http://purl.uniprot.org/uniprot/A0A7I7JH35 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/2492438:G6N19_RS20090 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSW6 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/2492438:G6N19_RS19015 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSJ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS13670 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPB3 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2492438:G6N19_RS11375 ^@ http://purl.uniprot.org/uniprot/A0A7I7JP79 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/2492438:G6N19_RS18345 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRT2 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/2492438:G6N19_RS00420 ^@ http://purl.uniprot.org/uniprot/A0A7I7JGJ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.|||Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.|||Homotetramer composed of a dimer of dimers. http://togogenome.org/gene/2492438:G6N19_RS20670 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EspG family.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS01930 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHW0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS13865 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRP8 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/2492438:G6N19_RS17585 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRK6 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/2492438:G6N19_RS13540 ^@ http://purl.uniprot.org/uniprot/A0A7I7JP85 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/2492438:G6N19_RS15285 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRH1 ^@ Function|||Similarity ^@ Belongs to the rubredoxin family.|||Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase. http://togogenome.org/gene/2492438:G6N19_RS04675 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIW3 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS18350 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS04245 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKM7 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/2492438:G6N19_RS13595 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQY5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/2492438:G6N19_RS19625 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUB5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS11260 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMS1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/2492438:G6N19_RS14870 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQ63 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/2492438:G6N19_RS16995 ^@ http://purl.uniprot.org/uniprot/A0A7I7JR19 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ A probable RNA-binding protein.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS02130 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHZ3 ^@ Similarity ^@ Belongs to the saccharopine dehydrogenase family. Enoyl reductase subfamily. http://togogenome.org/gene/2492438:G6N19_RS12525 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNI2 ^@ Similarity ^@ Belongs to the TfdA dioxygenase family. http://togogenome.org/gene/2492438:G6N19_RS17290 ^@ http://purl.uniprot.org/uniprot/A0A7I7JR81 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2492438:G6N19_RS02670 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHR4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/2492438:G6N19_RS20225 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUQ2 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/2492438:G6N19_RS00930 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIF4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons. http://togogenome.org/gene/2492438:G6N19_RS01775 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ80 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily. http://togogenome.org/gene/2492438:G6N19_RS04620 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIV0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS06555 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLG0 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/2492438:G6N19_RS18130 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS22 ^@ Cofactor|||Function ^@ Binds 1 [3Fe-4S] cluster.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/2492438:G6N19_RS00805 ^@ http://purl.uniprot.org/uniprot/A0A7I7JH75 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rieske iron-sulfur protein family.|||Cell membrane|||Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS09310 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLJ0 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/2492438:G6N19_RS05515 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKR1 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/2492438:G6N19_RS16710 ^@ http://purl.uniprot.org/uniprot/A0A7I7JR28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial histone-like protein family.|||cell wall http://togogenome.org/gene/2492438:G6N19_RS03480 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJF5 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.|||Belongs to the sirtuin family. Class III subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. http://togogenome.org/gene/2492438:G6N19_RS13765 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPJ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/2492438:G6N19_RS12595 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQ46 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the acetyltransferase family. MshD subfamily.|||Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/2492438:G6N19_RS00210 ^@ http://purl.uniprot.org/uniprot/A0A7I7JGC3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/2492438:G6N19_RS18730 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS43 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/2492438:G6N19_RS09300 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNG1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/2492438:G6N19_RS00165 ^@ http://purl.uniprot.org/uniprot/A0A7I7JGD6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/2492438:G6N19_RS02500 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJL2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/2492438:G6N19_RS05850 ^@ http://purl.uniprot.org/uniprot/A0A7I7JM74 ^@ Similarity ^@ Belongs to the UPF0336 family. http://togogenome.org/gene/2492438:G6N19_RS11430 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPF6 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/2492438:G6N19_RS13645 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQZ4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/2492438:G6N19_RS09090 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLT6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/2492438:G6N19_RS11210 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMR0 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/2492438:G6N19_RS05825 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKZ2 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/2492438:G6N19_RS05580 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLD3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS17190 ^@ http://purl.uniprot.org/uniprot/A0A7I7JR63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS13555 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPE4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/2492438:G6N19_RS16085 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQI1 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/2492438:G6N19_RS16650 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSH2 ^@ Function|||Similarity ^@ Belongs to the ectoine synthase family.|||Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant. http://togogenome.org/gene/2492438:G6N19_RS18320 ^@ http://purl.uniprot.org/uniprot/A0A7I7JU43 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2492438:G6N19_RS18715 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSD5 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/2492438:G6N19_RS00960 ^@ http://purl.uniprot.org/uniprot/A0A7I7JGS7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/2492438:G6N19_RS20120 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT63 ^@ Similarity ^@ Belongs to the mycobacterial PPE family. http://togogenome.org/gene/2492438:G6N19_RS20640 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIK5 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/2492438:G6N19_RS05265 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJN9 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/2492438:G6N19_RS00915 ^@ http://purl.uniprot.org/uniprot/A0A7I7JGP3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS04550 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKT8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS14495 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQZ1 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/2492438:G6N19_RS15380 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQ40 ^@ Similarity ^@ Belongs to the long-chain O-acyltransferase family. http://togogenome.org/gene/2492438:G6N19_RS14315 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRW6 ^@ Cofactor|||Similarity ^@ Belongs to the monomeric-type IDH family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/2492438:G6N19_RS09255 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLI2 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/2492438:G6N19_RS08135 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMT3 ^@ Similarity ^@ Belongs to the long-chain O-acyltransferase family. http://togogenome.org/gene/2492438:G6N19_RS01465 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2492438:G6N19_RS01675 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ64 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/2492438:G6N19_RS05175 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ62 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. http://togogenome.org/gene/2492438:G6N19_RS10430 ^@ http://purl.uniprot.org/uniprot/A0A7I7JP61 ^@ Function|||Similarity ^@ Belongs to the PemK/MazF family.|||Toxic component of a type II toxin-antitoxin (TA) system. http://togogenome.org/gene/2492438:G6N19_RS01430 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ07 ^@ Similarity ^@ Belongs to the mycobacterial PPE family. http://togogenome.org/gene/2492438:G6N19_RS00905 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIN6 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/2492438:G6N19_RS13085 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQ53 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/2492438:G6N19_RS06145 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLL5 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/2492438:G6N19_RS04430 ^@ http://purl.uniprot.org/uniprot/A0A7I7JK38 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/2492438:G6N19_RS19225 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSG4 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/2492438:G6N19_RS17440 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSL9 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/2492438:G6N19_RS01435 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJS5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/2492438:G6N19_RS13855 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPE6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/2492438:G6N19_RS12305 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQA9 ^@ Similarity ^@ Belongs to the HIBADH-related family. http://togogenome.org/gene/2492438:G6N19_RS20505 ^@ http://purl.uniprot.org/uniprot/A0A7I7JVC0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the malate synthase family. GlcB subfamily.|||Cytoplasm|||Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/2492438:G6N19_RS01955 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIN4 ^@ Similarity ^@ Belongs to the MmpS family. http://togogenome.org/gene/2492438:G6N19_RS07330 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKX1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK. http://togogenome.org/gene/2492438:G6N19_RS13605 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPF4 ^@ Similarity ^@ Belongs to the EccE family. http://togogenome.org/gene/2492438:G6N19_RS12755 ^@ http://purl.uniprot.org/uniprot/A0A7I7JR41 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS06205 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJU8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2492438:G6N19_RS18695 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTM0 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/2492438:G6N19_RS10960 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNZ5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS02120 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJF3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/2492438:G6N19_RS10900 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMK2 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/2492438:G6N19_RS17150 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSR1 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/2492438:G6N19_RS16735 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQX9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS02825 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHS6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/2492438:G6N19_RS17000 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSE4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/2492438:G6N19_RS12715 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQF0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS13400 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPB8 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/2492438:G6N19_RS08670 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLK5 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/2492438:G6N19_RS00170 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHJ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS06130 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLR4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS15085 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRC8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS13590 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPA0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2492438:G6N19_RS04605 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/2492438:G6N19_RS02660 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHP7 ^@ Similarity|||Subunit ^@ Belongs to the glutaminase family.|||Homotetramer. http://togogenome.org/gene/2492438:G6N19_RS13655 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPG5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/2492438:G6N19_RS10075 ^@ http://purl.uniprot.org/uniprot/A0A7I7JME0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS20610 ^@ http://purl.uniprot.org/uniprot/A0A7I7JV00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS11470 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMW4 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/2492438:G6N19_RS00365 ^@ http://purl.uniprot.org/uniprot/A0A7I7JGC6 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/2492438:G6N19_RS07280 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKW1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/2492438:G6N19_RS12045 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNH1 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/2492438:G6N19_RS18735 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS50 ^@ Function|||Similarity ^@ Belongs to the RapZ-like family.|||Displays ATPase and GTPase activities. http://togogenome.org/gene/2492438:G6N19_RS14685 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPW5 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/2492438:G6N19_RS04000 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIZ7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS16645 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS75 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PhyH family. EctD subfamily.|||Homodimer.|||Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine. http://togogenome.org/gene/2492438:G6N19_RS20325 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUS5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS05670 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJI1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/2492438:G6N19_RS08015 ^@ http://purl.uniprot.org/uniprot/A0A7I7JL76 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/2492438:G6N19_RS03100 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIH6 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/2492438:G6N19_RS01155 ^@ http://purl.uniprot.org/uniprot/A0A7I7JGW8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Acyl carrier protein involved in meromycolate extension.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS08000 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKX3 ^@ Similarity ^@ Belongs to the WrbA family. http://togogenome.org/gene/2492438:G6N19_RS01750 ^@ http://purl.uniprot.org/uniprot/A0A7I7JH90 ^@ Function ^@ Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core. http://togogenome.org/gene/2492438:G6N19_RS19510 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUR9 ^@ Similarity|||Subunit ^@ Belongs to the pyruvate kinase family.|||Homotetramer. http://togogenome.org/gene/2492438:G6N19_RS16160 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS53 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2492438:G6N19_RS17270 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRL9 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/2492438:G6N19_RS00140 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ13 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS13035 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQ41 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS11045 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPI2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS10950 ^@ http://purl.uniprot.org/uniprot/A0A7I7JML0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/2492438:G6N19_RS20615 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT97 ^@ Similarity ^@ Belongs to the mycobacterial PPE family. http://togogenome.org/gene/2492438:G6N19_RS03310 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKR3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS17785 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRH8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/2492438:G6N19_RS18880 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS78 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/2492438:G6N19_RS00460 ^@ http://purl.uniprot.org/uniprot/A0A7I7JGH2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2492438:G6N19_RS20465 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTD3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/2492438:G6N19_RS01260 ^@ http://purl.uniprot.org/uniprot/A0A7I7JH25 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cutinase family.|||Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.|||Secreted http://togogenome.org/gene/2492438:G6N19_RS02610 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS17845 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT50 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/2492438:G6N19_RS20575 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT68 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/2492438:G6N19_RS00090 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ04 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/2492438:G6N19_RS12115 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQ50 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS00330 ^@ http://purl.uniprot.org/uniprot/A0A7I7JI37 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/2492438:G6N19_RS18890 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTF2 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/2492438:G6N19_RS02535 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIY3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/2492438:G6N19_RS17105 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRA5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS20680 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIK5 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/2492438:G6N19_RS17910 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTW2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/2492438:G6N19_RS02300 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHI4 ^@ Similarity ^@ Belongs to the long-chain O-acyltransferase family. http://togogenome.org/gene/2492438:G6N19_RS16400 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSB0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ETF alpha-subunit/FixB family.|||Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/2492438:G6N19_RS13550 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRJ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/2492438:G6N19_RS01160 ^@ http://purl.uniprot.org/uniprot/A0A7I7JGV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS02760 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKF5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS13530 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQE6 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/2492438:G6N19_RS11000 ^@ http://purl.uniprot.org/uniprot/A0A7I7JML7 ^@ Function|||Similarity ^@ Belongs to the EgtB family.|||Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. http://togogenome.org/gene/2492438:G6N19_RS01635 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJW0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/2492438:G6N19_RS17215 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTJ0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/2492438:G6N19_RS20560 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sbp family.|||Cell membrane http://togogenome.org/gene/2492438:G6N19_RS01725 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ72 ^@ Similarity ^@ Belongs to the thioesterase family. http://togogenome.org/gene/2492438:G6N19_RS17790 ^@ http://purl.uniprot.org/uniprot/A0A7I7JST1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS04320 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EspG family.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS14550 ^@ http://purl.uniprot.org/uniprot/A0A7I7JR85 ^@ Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer. http://togogenome.org/gene/2492438:G6N19_RS19930 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT19 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/2492438:G6N19_RS00150 ^@ http://purl.uniprot.org/uniprot/A0A7I7JI85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS05140 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKI5 ^@ Cofactor|||Similarity ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit. http://togogenome.org/gene/2492438:G6N19_RS00880 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIE1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/2492438:G6N19_RS17870 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTB1 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/2492438:G6N19_RS20060 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUN6 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/2492438:G6N19_RS13430 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQK8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/2492438:G6N19_RS14460 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRF7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS17995 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT79 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/2492438:G6N19_RS14275 ^@ http://purl.uniprot.org/uniprot/A0A7I7JR93 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS02565 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJK2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS01065 ^@ http://purl.uniprot.org/uniprot/A0A7I7JI31 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/2492438:G6N19_RS00840 ^@ http://purl.uniprot.org/uniprot/A0A7I7JH84 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/2492438:G6N19_RS03020 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJS1 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family. http://togogenome.org/gene/2492438:G6N19_RS05750 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJX2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/2492438:G6N19_RS13870 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPL0 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/2492438:G6N19_RS04525 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIT3 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/2492438:G6N19_RS15035 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRB8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/2492438:G6N19_RS18450 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT71 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/2492438:G6N19_RS19700 ^@ http://purl.uniprot.org/uniprot/A0A7I7JU75 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/2492438:G6N19_RS10045 ^@ http://purl.uniprot.org/uniprot/A0A7I7JM16 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class II aldolase/RraA-like family.|||Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.|||Homotrimer. http://togogenome.org/gene/2492438:G6N19_RS18975 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSB1 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/2492438:G6N19_RS17280 ^@ http://purl.uniprot.org/uniprot/A0A7I7JR70 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/2492438:G6N19_RS18570 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSA5 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/2492438:G6N19_RS08540 ^@ http://purl.uniprot.org/uniprot/A0A7I7JL47 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/2492438:G6N19_RS09685 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNP3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS20115 ^@ http://purl.uniprot.org/uniprot/A0A7I7JV38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS12600 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNR2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PstS family.|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/2492438:G6N19_RS20420 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTC3 ^@ Similarity ^@ Belongs to the Apa family. http://togogenome.org/gene/2492438:G6N19_RS05290 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKL5 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/2492438:G6N19_RS16290 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQU2 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/2492438:G6N19_RS05920 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLG5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS11540 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQG0 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/2492438:G6N19_RS20040 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS05070 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKY1 ^@ Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||Could possibly oxidize fatty acids using specific components. http://togogenome.org/gene/2492438:G6N19_RS17450 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRH4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/2492438:G6N19_RS03565 ^@ http://purl.uniprot.org/uniprot/A0A7I7JI81 ^@ Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||Could possibly oxidize fatty acids using specific components. http://togogenome.org/gene/2492438:G6N19_RS13290 ^@ http://purl.uniprot.org/uniprot/A0A7I7JP43 ^@ Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||Could possibly oxidize fatty acids using specific components. http://togogenome.org/gene/2492438:G6N19_RS07365 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKV8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/2492438:G6N19_RS00670 ^@ http://purl.uniprot.org/uniprot/A0A7I7JGI5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/2492438:G6N19_RS02855 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJX9 ^@ Similarity ^@ Belongs to the mycobacterial PPE family. http://togogenome.org/gene/2492438:G6N19_RS03570 ^@ http://purl.uniprot.org/uniprot/A0A7I7JI91 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/2492438:G6N19_RS18020 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTD5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.|||Cytoplasm|||Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III. http://togogenome.org/gene/2492438:G6N19_RS16395 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS23 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ETF beta-subunit/FixA family.|||Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/2492438:G6N19_RS02095 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHF3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/2492438:G6N19_RS08200 ^@ http://purl.uniprot.org/uniprot/A0A7I7JL11 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|||Cytoplasm|||Monomer. http://togogenome.org/gene/2492438:G6N19_RS09145 ^@ http://purl.uniprot.org/uniprot/A0A7I7JP05 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/2492438:G6N19_RS04410 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKI1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 39 family.|||Cell membrane|||Membrane|||Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. http://togogenome.org/gene/2492438:G6N19_RS13275 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNW9 ^@ Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||Could possibly oxidize fatty acids using specific components. http://togogenome.org/gene/2492438:G6N19_RS01100 ^@ http://purl.uniprot.org/uniprot/A0A7I7JGV8 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/2492438:G6N19_RS02905 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/2492438:G6N19_RS13920 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPL8 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/2492438:G6N19_RS03965 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIG6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS17600 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT01 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/2492438:G6N19_RS06910 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLN0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cell surface|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.|||capsule|||cell wall http://togogenome.org/gene/2492438:G6N19_RS18265 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTL9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/2492438:G6N19_RS13770 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQZ7 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/2492438:G6N19_RS17610 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTR2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the thymidylate synthase ThyX family.|||Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.|||Homotetramer. http://togogenome.org/gene/2492438:G6N19_RS01645 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ52 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/2492438:G6N19_RS06600 ^@ http://purl.uniprot.org/uniprot/A0A7I7JK35 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS19030 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS01470 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2492438:G6N19_RS13860 ^@ http://purl.uniprot.org/uniprot/A0A7I7JR34 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/2492438:G6N19_RS04085 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ02 ^@ Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||Could possibly oxidize fatty acids using specific components. http://togogenome.org/gene/2492438:G6N19_RS07215 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKT3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2492438:G6N19_RS20135 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS02620 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHP0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.|||Homodimer.|||Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. http://togogenome.org/gene/2492438:G6N19_RS12610 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNW6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/2492438:G6N19_RS13955 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPG4 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/2492438:G6N19_RS19580 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSP5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/2492438:G6N19_RS18460 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS58 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/2492438:G6N19_RS15595 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRV4 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/2492438:G6N19_RS02175 ^@ http://purl.uniprot.org/uniprot/A0A7I7JK54 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/2492438:G6N19_RS04705 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLK1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/2492438:G6N19_RS04985 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKF6 ^@ Similarity ^@ Belongs to the HipA Ser/Thr kinase family. http://togogenome.org/gene/2492438:G6N19_RS00715 ^@ http://purl.uniprot.org/uniprot/A0A7I7JGM6 ^@ Similarity ^@ Belongs to the class-II DAHP synthase family. http://togogenome.org/gene/2492438:G6N19_RS03625 ^@ http://purl.uniprot.org/uniprot/A0A7I7JI86 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/2492438:G6N19_RS05855 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJZ2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/2492438:G6N19_RS09040 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLE5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CwsA family.|||Cell membrane|||Required for regulated cell division, cell wall synthesis and the maintenance of cell shape. http://togogenome.org/gene/2492438:G6N19_RS13630 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQG4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/2492438:G6N19_RS05675 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKV5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/2492438:G6N19_RS13565 ^@ http://purl.uniprot.org/uniprot/A0A7I7JP34 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/2492438:G6N19_RS18690 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTB8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/2492438:G6N19_RS01825 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ90 ^@ Function|||Subunit ^@ Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.|||Monomer. http://togogenome.org/gene/2492438:G6N19_RS02895 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJH7 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Catalyzes the reversible hydration of carbon dioxide to form bicarbonate. http://togogenome.org/gene/2492438:G6N19_RS10920 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMT0 ^@ Function|||Similarity ^@ Belongs to the rubredoxin family.|||Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase. http://togogenome.org/gene/2492438:G6N19_RS18230 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS38 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/2492438:G6N19_RS04835 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKC2 ^@ Cofactor|||Similarity ^@ Belongs to the fatty acid desaturase type 2 family.|||Binds 2 iron ions per subunit. http://togogenome.org/gene/2492438:G6N19_RS08345 ^@ http://purl.uniprot.org/uniprot/A0A7I7JL12 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/2492438:G6N19_RS14510 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRG7 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/2492438:G6N19_RS00950 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHA2 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/2492438:G6N19_RS19430 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSI7 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/2492438:G6N19_RS16500 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSD0 ^@ Function|||Similarity ^@ Belongs to the TenA family.|||Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. http://togogenome.org/gene/2492438:G6N19_RS15520 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS10 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/2492438:G6N19_RS01815 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIZ4 ^@ Similarity ^@ Belongs to the transglycosylase family. Rpf subfamily. http://togogenome.org/gene/2492438:G6N19_RS16210 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS63 ^@ Function|||Similarity ^@ Belongs to the NrdI family.|||Probably involved in ribonucleotide reductase function. http://togogenome.org/gene/2492438:G6N19_RS15670 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS31 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/2492438:G6N19_RS15705 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSN4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0182 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS20570 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS14070 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPQ0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cell surface|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.|||capsule|||cell wall http://togogenome.org/gene/2492438:G6N19_RS00885 ^@ http://purl.uniprot.org/uniprot/A0A7I7JH94 ^@ Similarity ^@ Belongs to the adenylyl cyclase class-3 family. http://togogenome.org/gene/2492438:G6N19_RS19160 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUK5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2492438:G6N19_RS12350 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNM0 ^@ Function|||Similarity ^@ Belongs to the AlaDH/PNT family.|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/2492438:G6N19_RS06685 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKJ2 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/2492438:G6N19_RS16535 ^@ http://purl.uniprot.org/uniprot/A0A7I7JR05 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/2492438:G6N19_RS17615 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRV1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/2492438:G6N19_RS13760 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRN1 ^@ Function|||Similarity ^@ Belongs to the UPF0677 family.|||Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. http://togogenome.org/gene/2492438:G6N19_RS15020 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPW9 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/2492438:G6N19_RS20330 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT39 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterioferritin family.|||Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/2492438:G6N19_RS10035 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLZ2 ^@ Similarity ^@ Belongs to the FAD-binding monooxygenase family. http://togogenome.org/gene/2492438:G6N19_RS16155 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS16045 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRW7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/2492438:G6N19_RS20490 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUP5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS05725 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKW8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/2492438:G6N19_RS18300 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2492438:G6N19_RS06290 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLQ6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/2492438:G6N19_RS12725 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNT7 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/2492438:G6N19_RS20345 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUA3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2492438:G6N19_RS13825 ^@ http://purl.uniprot.org/uniprot/A0A7I7JP93 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/2492438:G6N19_RS16505 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQY0 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/2492438:G6N19_RS04515 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS09205 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLH3 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/2492438:G6N19_RS20415 ^@ http://purl.uniprot.org/uniprot/A0A7I7JVA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS10925 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/2492438:G6N19_RS15920 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQT6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2492438:G6N19_RS20205 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT54 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/2492438:G6N19_RS04005 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS00585 ^@ http://purl.uniprot.org/uniprot/A0A7I7JI89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DivIVA family.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS06815 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLT9 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/2492438:G6N19_RS15080 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPY4 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/2492438:G6N19_RS17835 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRI8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/2492438:G6N19_RS01165 ^@ http://purl.uniprot.org/uniprot/A0A7I7JH06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS16180 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQY8 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/2492438:G6N19_RS18740 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTC6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/2492438:G6N19_RS16285 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQM2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS07310 ^@ http://purl.uniprot.org/uniprot/A0A7I7JM41 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS18500 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT82 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/2492438:G6N19_RS14880 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPU4 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/2492438:G6N19_RS19365 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSQ9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS00370 ^@ http://purl.uniprot.org/uniprot/A0A7I7JGI7 ^@ Similarity ^@ Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily. http://togogenome.org/gene/2492438:G6N19_RS12530 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNP5 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS04555 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLG8 ^@ Similarity ^@ Belongs to the AccD/PCCB family. http://togogenome.org/gene/2492438:G6N19_RS07095 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKC7 ^@ Function ^@ Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. http://togogenome.org/gene/2492438:G6N19_RS03700 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKY8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2492438:G6N19_RS07575 ^@ http://purl.uniprot.org/uniprot/A0A7I7JL15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EspG family.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS07285 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/2492438:G6N19_RS07675 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMK1 ^@ Cofactor ^@ Binds 4 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/2492438:G6N19_RS00610 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIH5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/2492438:G6N19_RS15185 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRF1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the CofD family.|||Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS12425 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNG7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/2492438:G6N19_RS20845 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUW7 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/2492438:G6N19_RS12125 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNA5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2492438:G6N19_RS06960 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS02560 ^@ http://purl.uniprot.org/uniprot/A0A7I7JI71 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/2492438:G6N19_RS16575 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSM2 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/2492438:G6N19_RS19425 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS01050 ^@ http://purl.uniprot.org/uniprot/A0A7I7JGU7 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/2492438:G6N19_RS01305 ^@ http://purl.uniprot.org/uniprot/A0A7I7JGY4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2492438:G6N19_RS17080 ^@ http://purl.uniprot.org/uniprot/A0A7I7JR37 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/2492438:G6N19_RS07935 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKT0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/2492438:G6N19_RS16185 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSD6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/2492438:G6N19_RS09290 ^@ http://purl.uniprot.org/uniprot/A0A7I7JP33 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/2492438:G6N19_RS13640 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPB0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/2492438:G6N19_RS20660 ^@ http://purl.uniprot.org/uniprot/A0A7I7JV13 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/2492438:G6N19_RS17135 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRB9 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS16205 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRZ5 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Electron transport system for the ribonucleotide reductase system NrdEF. http://togogenome.org/gene/2492438:G6N19_RS04035 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIZ3 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/2492438:G6N19_RS01190 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHF7 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS00345 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ53 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.|||The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/2492438:G6N19_RS13650 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRL2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/2492438:G6N19_RS10170 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPL2 ^@ Similarity ^@ Belongs to the MmpS family. http://togogenome.org/gene/2492438:G6N19_RS18185 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTG1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.|||Cell membrane|||Contains a di-nuclear catalytic Mg(2+) center.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS02295 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJG4 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/2492438:G6N19_RS13570 ^@ http://purl.uniprot.org/uniprot/A0A7I7JP92 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/2492438:G6N19_RS07145 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKD6 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/2492438:G6N19_RS18445 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRW8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS00720 ^@ http://purl.uniprot.org/uniprot/A0A7I7JGJ6 ^@ Cofactor|||Function|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.|||Homodimer. http://togogenome.org/gene/2492438:G6N19_RS09815 ^@ http://purl.uniprot.org/uniprot/A0A7I7JM69 ^@ Similarity ^@ Belongs to the MmpS family. http://togogenome.org/gene/2492438:G6N19_RS06965 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKN8 ^@ Function ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate. http://togogenome.org/gene/2492438:G6N19_RS17455 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT61 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/2492438:G6N19_RS15220 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQ11 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS06475 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMJ7 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/2492438:G6N19_RS07870 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNA9 ^@ Function|||Subunit ^@ Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.|||Monomer. http://togogenome.org/gene/2492438:G6N19_RS02850 ^@ http://purl.uniprot.org/uniprot/A0A7I7JID9 ^@ Similarity ^@ Belongs to the mycobacterial PPE family. http://togogenome.org/gene/2492438:G6N19_RS08275 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS12445 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQ18 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/2492438:G6N19_RS18990 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0353 family.|||Cell membrane http://togogenome.org/gene/2492438:G6N19_RS01450 ^@ http://purl.uniprot.org/uniprot/A0A7I7JH23 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/2492438:G6N19_RS11105 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMP2 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/2492438:G6N19_RS13320 ^@ http://purl.uniprot.org/uniprot/A0A7I7JP41 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS00340 ^@ http://purl.uniprot.org/uniprot/A0A7I7JID4 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/2492438:G6N19_RS08295 ^@ http://purl.uniprot.org/uniprot/A0A7I7JL00 ^@ Cofactor|||Similarity ^@ Belongs to the truncated hemoglobin family. Group I subfamily.|||Binds 1 heme group per subunit. http://togogenome.org/gene/2492438:G6N19_RS12815 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQG8 ^@ Similarity ^@ Belongs to the HIBADH-related family. http://togogenome.org/gene/2492438:G6N19_RS03095 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJL8 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/2492438:G6N19_RS12895 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNW8 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS06280 ^@ http://purl.uniprot.org/uniprot/A0A7I7JME8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS03285 ^@ http://purl.uniprot.org/uniprot/A0A7I7JI26 ^@ Similarity ^@ Belongs to the MmpS family. http://togogenome.org/gene/2492438:G6N19_RS17320 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRN0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/2492438:G6N19_RS00925 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHZ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS13575 ^@ http://purl.uniprot.org/uniprot/A0A7I7JP26 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/2492438:G6N19_RS11780 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNC0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2492438:G6N19_RS11250 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPM5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS03875 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIE7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/2492438:G6N19_RS04540 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKD7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/2492438:G6N19_RS00195 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ24 ^@ Similarity ^@ Belongs to the adenylyl cyclase class-3 family. http://togogenome.org/gene/2492438:G6N19_RS19725 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2492438:G6N19_RS17625 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRD9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2492438:G6N19_RS15905 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQK0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2492438:G6N19_RS17305 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRE3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/2492438:G6N19_RS15915 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSS7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2492438:G6N19_RS06360 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLB6 ^@ Similarity ^@ Belongs to the long-chain O-acyltransferase family. http://togogenome.org/gene/2492438:G6N19_RS02765 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIC0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS04850 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKZ7 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS04565 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKM4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS00910 ^@ http://purl.uniprot.org/uniprot/A0A7I7JGR9 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/2492438:G6N19_RS07695 ^@ http://purl.uniprot.org/uniprot/A0A7I7JM34 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.|||Binds 2 nickel ions per subunit.|||Carbamylation allows a single lysine to coordinate two nickel ions.|||Carboxylation allows a single lysine to coordinate two nickel ions.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/2492438:G6N19_RS15940 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQF7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2492438:G6N19_RS06545 ^@ http://purl.uniprot.org/uniprot/A0A7I7JK14 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/2492438:G6N19_RS20030 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSY4 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/2492438:G6N19_RS20565 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUZ1 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/2492438:G6N19_RS20495 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTB5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS15165 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRT9 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/2492438:G6N19_RS01145 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHE2 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/2492438:G6N19_RS04495 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ83 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/2492438:G6N19_RS18535 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2492438:G6N19_RS15560 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSK3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/2492438:G6N19_RS02365 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHL7 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/2492438:G6N19_RS05660 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJH4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/2492438:G6N19_RS18565 ^@ http://purl.uniprot.org/uniprot/A0A7I7JU88 ^@ Function|||Similarity ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. http://togogenome.org/gene/2492438:G6N19_RS02615 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHN8 ^@ Function|||Similarity ^@ Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/2492438:G6N19_RS07140 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKC4 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS00640 ^@ http://purl.uniprot.org/uniprot/A0A7I7JH39 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/2492438:G6N19_RS03550 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKW0 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/2492438:G6N19_RS16660 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSR3 ^@ Function|||Similarity ^@ Belongs to the acetyltransferase family. EctA subfamily.|||Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A. http://togogenome.org/gene/2492438:G6N19_RS17140 ^@ http://purl.uniprot.org/uniprot/A0A7I7JR49 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/2492438:G6N19_RS03175 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHZ9 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/2492438:G6N19_RS10600 ^@ http://purl.uniprot.org/uniprot/A0A7I7JML8 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/2492438:G6N19_RS19045 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTT9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the methylmalonyl-CoA mutase family.|||Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.|||Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/2492438:G6N19_RS08595 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMJ0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2492438:G6N19_RS13775 ^@ http://purl.uniprot.org/uniprot/A0A7I7JP77 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/2492438:G6N19_RS15505 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS04 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS17665 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRV8 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/2492438:G6N19_RS18225 ^@ http://purl.uniprot.org/uniprot/A0A7I7JU23 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/2492438:G6N19_RS05230 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ75 ^@ Similarity ^@ Belongs to the MoaD family. http://togogenome.org/gene/2492438:G6N19_RS20900 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTK0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS18260 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS26 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/2492438:G6N19_RS19655 ^@ http://purl.uniprot.org/uniprot/A0A7I7JST9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase-binding protein RbpA family.|||Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.|||Forms a complex with the RNAP catalytic core and with free principal sigma factors.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS09150 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLU6 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/2492438:G6N19_RS17110 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT00 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS06790 ^@ http://purl.uniprot.org/uniprot/A0A7I7JM14 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/2492438:G6N19_RS16580 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQU9 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/2492438:G6N19_RS17795 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT40 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/2492438:G6N19_RS16260 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQS4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS20210 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUR3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2492438:G6N19_RS19020 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTX9 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/2492438:G6N19_RS08915 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNA3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS01580 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHP8 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/2492438:G6N19_RS03540 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIQ6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2492438:G6N19_RS00145 ^@ http://purl.uniprot.org/uniprot/A0A7I7JGS3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/2492438:G6N19_RS07085 ^@ http://purl.uniprot.org/uniprot/A0A7I7JM63 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS12625 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNR7 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/2492438:G6N19_RS07050 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKE1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/2492438:G6N19_RS18520 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS95 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS05505 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJD7 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/2492438:G6N19_RS00440 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS18475 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS88 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/2492438:G6N19_RS19670 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSX3 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/2492438:G6N19_RS17050 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSP1 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/2492438:G6N19_RS10915 ^@ http://purl.uniprot.org/uniprot/A0A7I7JP47 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit.|||Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase. http://togogenome.org/gene/2492438:G6N19_RS17005 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/2492438:G6N19_RS11610 ^@ http://purl.uniprot.org/uniprot/A0A7I7JN01 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/2492438:G6N19_RS15500 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQC6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS01070 ^@ http://purl.uniprot.org/uniprot/A0A7I7JII5 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/2492438:G6N19_RS18380 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2492438:G6N19_RS14050 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQX4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD. http://togogenome.org/gene/2492438:G6N19_RS15215 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRW0 ^@ Cofactor|||Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/2492438:G6N19_RS01935 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJA2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS08330 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNJ2 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS03420 ^@ http://purl.uniprot.org/uniprot/A0A7I7JI51 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/2492438:G6N19_RS19575 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUA4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/2492438:G6N19_RS01265 ^@ http://purl.uniprot.org/uniprot/A0A7I7JI72 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/2492438:G6N19_RS00255 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIA6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/2492438:G6N19_RS10880 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQ23 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/2492438:G6N19_RS01980 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHW6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/2492438:G6N19_RS17310 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT33 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/2492438:G6N19_RS06330 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMG4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the TPP enzyme family. MenD subfamily.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).|||Homodimer. http://togogenome.org/gene/2492438:G6N19_RS00215 ^@ http://purl.uniprot.org/uniprot/A0A7I7JG90 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/2492438:G6N19_RS05125 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ48 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/2492438:G6N19_RS02640 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJP2 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/2492438:G6N19_RS19165 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSM0 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/2492438:G6N19_RS15930 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQF3 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/2492438:G6N19_RS02420 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHM4 ^@ Similarity ^@ Belongs to the MmpS family. http://togogenome.org/gene/2492438:G6N19_RS05435 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLY3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS18650 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM86 family.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS17060 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSZ1 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS13840 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQK7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/2492438:G6N19_RS20455 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUW9 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/2492438:G6N19_RS20665 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EccD/Snm4 family.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS16485 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQZ0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS07315 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKU9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2492438:G6N19_RS18485 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRX8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/2492438:G6N19_RS12795 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNV1 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/2492438:G6N19_RS20395 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUB4 ^@ Similarity ^@ Belongs to the XFP family. http://togogenome.org/gene/2492438:G6N19_RS15345 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQ95 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/2492438:G6N19_RS18720 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTR6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.|||Homopentamer. http://togogenome.org/gene/2492438:G6N19_RS11475 ^@ http://purl.uniprot.org/uniprot/A0A7I7JP99 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS06575 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMM0 ^@ Similarity ^@ Belongs to the UPF0336 family. http://togogenome.org/gene/2492438:G6N19_RS03220 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJV1 ^@ Function|||Similarity ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Involved in the biosynthesis of ADP-glucose, a building block, required in the biosynthesis of maltose-1-phosphate (M1P) and in the elongation reactions to produce linear alpha-1,4-glucans. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/2492438:G6N19_RS13755 ^@ http://purl.uniprot.org/uniprot/A0A7I7JR16 ^@ Function|||Similarity ^@ Belongs to the UPF0677 family.|||Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. http://togogenome.org/gene/2492438:G6N19_RS05840 ^@ http://purl.uniprot.org/uniprot/A0A7I7JK01 ^@ Similarity ^@ Belongs to the UPF0336 family. http://togogenome.org/gene/2492438:G6N19_RS08290 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMW1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS00245 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ35 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/2492438:G6N19_RS20350 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUL3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS10985 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQ44 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/2492438:G6N19_RS08665 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNR0 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/2492438:G6N19_RS10610 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPW0 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/2492438:G6N19_RS19000 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSF8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/2492438:G6N19_RS17020 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS09160 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLG4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2492438:G6N19_RS17325 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT16 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/2492438:G6N19_RS07895 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKV3 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/2492438:G6N19_RS04670 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIW0 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/2492438:G6N19_RS12640 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQ56 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PstS family.|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/2492438:G6N19_RS14380 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPJ5 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/2492438:G6N19_RS09305 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLJ1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/2492438:G6N19_RS05430 ^@ http://purl.uniprot.org/uniprot/A0A7I7JL99 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/2492438:G6N19_RS20280 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT29 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS17865 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRZ2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DtxR/MntR family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2492438:G6N19_RS12270 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQ71 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/2492438:G6N19_RS20445 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUN1 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS08825 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EspG family.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS01180 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHG7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2492438:G6N19_RS12630 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNJ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/2492438:G6N19_RS20840 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS16540 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQU8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/2492438:G6N19_RS08280 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNI5 ^@ Similarity ^@ Belongs to the CsoR family. http://togogenome.org/gene/2492438:G6N19_RS08225 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS18765 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSE1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/2492438:G6N19_RS07380 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS16900 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSC3 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/2492438:G6N19_RS18505 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTI6 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/2492438:G6N19_RS12660 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNX6 ^@ Cofactor|||Similarity ^@ Belongs to the fatty acid desaturase type 2 family.|||Binds 2 iron ions per subunit. http://togogenome.org/gene/2492438:G6N19_RS16560 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSP7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2492438:G6N19_RS03755 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIU7 ^@ Function|||Similarity ^@ Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.|||Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. http://togogenome.org/gene/2492438:G6N19_RS07920 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNB8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS01605 ^@ http://purl.uniprot.org/uniprot/A0A7I7JH59 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/2492438:G6N19_RS17265 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTJ9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS11820 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPZ7 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/2492438:G6N19_RS02090 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHE9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/2492438:G6N19_RS19695 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTX0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS00295 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ44 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm|||In the C-terminal section; belongs to the UPF0157 (GrpB) family.|||In the N-terminal section; belongs to the CoaE family. http://togogenome.org/gene/2492438:G6N19_RS08150 ^@ http://purl.uniprot.org/uniprot/A0A7I7JL08 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS17040 ^@ http://purl.uniprot.org/uniprot/A0A7I7JR29 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/2492438:G6N19_RS12540 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS15640 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRP6 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/2492438:G6N19_RS00495 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ82 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2492438:G6N19_RS18595 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTA2 ^@ Similarity ^@ Belongs to the OMP decarboxylase family. Type 2 subfamily. http://togogenome.org/gene/2492438:G6N19_RS19675 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUC9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS16630 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQW0 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS04110 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIK2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS02160 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ47 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/2492438:G6N19_RS14215 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRV2 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/2492438:G6N19_RS17195 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSH1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/2492438:G6N19_RS05885 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJM4 ^@ Function|||Similarity ^@ Belongs to the cyanase family.|||Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. http://togogenome.org/gene/2492438:G6N19_RS19405 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUA1 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/2492438:G6N19_RS04175 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIK5 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/2492438:G6N19_RS16590 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQV7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2492438:G6N19_RS11560 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMZ2 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. http://togogenome.org/gene/2492438:G6N19_RS18685 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS39 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/2492438:G6N19_RS20140 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSX6 ^@ Similarity ^@ Belongs to the MmpS family. http://togogenome.org/gene/2492438:G6N19_RS09075 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLS0 ^@ Similarity ^@ Belongs to the UPF0232 family. http://togogenome.org/gene/2492438:G6N19_RS12685 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPX1 ^@ Similarity ^@ Belongs to the TfdA dioxygenase family. http://togogenome.org/gene/2492438:G6N19_RS00265 ^@ http://purl.uniprot.org/uniprot/A0A7I7JGA4 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/2492438:G6N19_RS02015 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHZ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS01665 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIW8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/2492438:G6N19_RS07690 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKR4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease beta subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/2492438:G6N19_RS16980 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSU7 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/2492438:G6N19_RS02310 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHJ0 ^@ Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||Could possibly oxidize fatty acids using specific components. http://togogenome.org/gene/2492438:G6N19_RS14730 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPR6 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS03170 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJU4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatB family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/2492438:G6N19_RS02635 ^@ http://purl.uniprot.org/uniprot/A0A7I7JIA5 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/2492438:G6N19_RS06700 ^@ http://purl.uniprot.org/uniprot/A0A7I7JK52 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/2492438:G6N19_RS19025 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSC1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS05130 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ54 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/2492438:G6N19_RS20905 ^@ http://purl.uniprot.org/uniprot/A0A7I7JV55 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/2492438:G6N19_RS13515 ^@ http://purl.uniprot.org/uniprot/A0A7I7JP21 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS16705 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSI2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/2492438:G6N19_RS17555 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRJ1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS07875 ^@ http://purl.uniprot.org/uniprot/A0A7I7JL72 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/2492438:G6N19_RS07090 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKB6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. http://togogenome.org/gene/2492438:G6N19_RS00595 ^@ http://purl.uniprot.org/uniprot/A0A7I7JII2 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/2492438:G6N19_RS20970 ^@ http://purl.uniprot.org/uniprot/A0A7I7JG71 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/2492438:G6N19_RS17850 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRP7 ^@ Cofactor|||Domain|||Function|||Similarity ^@ Belongs to the nitrobindin family.|||Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.|||Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.|||Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo. http://togogenome.org/gene/2492438:G6N19_RS20430 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT58 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/2492438:G6N19_RS18285 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRS6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/2492438:G6N19_RS07345 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKH3 ^@ Similarity ^@ Belongs to the globin family. Two-domain flavohemoproteins subfamily.|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. http://togogenome.org/gene/2492438:G6N19_RS02265 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHK1 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/2492438:G6N19_RS12100 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQ70 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/2492438:G6N19_RS05385 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLX4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS12355 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQB9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/2492438:G6N19_RS18830 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS65 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS02170 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJG2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/2492438:G6N19_RS02385 ^@ http://purl.uniprot.org/uniprot/A0A7I7JI54 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS06415 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLK7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Homohexamer. Dimer of a homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS09020 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNC2 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/2492438:G6N19_RS06215 ^@ http://purl.uniprot.org/uniprot/A0A7I7JL80 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/2492438:G6N19_RS06310 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLA6 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/2492438:G6N19_RS12645 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNS4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/2492438:G6N19_RS06270 ^@ http://purl.uniprot.org/uniprot/A0A7I7JK95 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/2492438:G6N19_RS17420 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRQ1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2492438:G6N19_RS14150 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQZ5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 65 family. http://togogenome.org/gene/2492438:G6N19_RS17645 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/2492438:G6N19_RS16905 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSL5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/2492438:G6N19_RS16555 ^@ http://purl.uniprot.org/uniprot/A0A7I7JR00 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/2492438:G6N19_RS16655 ^@ http://purl.uniprot.org/uniprot/A0A7I7JR18 ^@ Function|||Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.|||Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate. http://togogenome.org/gene/2492438:G6N19_RS08195 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKX5 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/2492438:G6N19_RS14245 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQT9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS01790 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJ77 ^@ Similarity ^@ Belongs to the CsoR family. http://togogenome.org/gene/2492438:G6N19_RS17045 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSE8 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/2492438:G6N19_RS16005 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQM1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS11315 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMT1 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/2492438:G6N19_RS12390 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPS0 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/2492438:G6N19_RS10230 ^@ http://purl.uniprot.org/uniprot/A0A7I7JP01 ^@ Similarity ^@ Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. http://togogenome.org/gene/2492438:G6N19_RS17335 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRF3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS01670 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHS5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/2492438:G6N19_RS19330 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSG8 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/2492438:G6N19_RS01170 ^@ http://purl.uniprot.org/uniprot/A0A7I7JI48 ^@ Similarity ^@ Belongs to the AccD/PCCB family. http://togogenome.org/gene/2492438:G6N19_RS18615 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUA0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/2492438:G6N19_RS07445 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLY7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.|||Homotrimer. http://togogenome.org/gene/2492438:G6N19_RS19475 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSL8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/2492438:G6N19_RS02720 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJM7 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/2492438:G6N19_RS18120 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRV0 ^@ Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||Could possibly oxidize fatty acids using specific components. http://togogenome.org/gene/2492438:G6N19_RS02400 ^@ http://purl.uniprot.org/uniprot/A0A7I7JI43 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/2492438:G6N19_RS00160 ^@ http://purl.uniprot.org/uniprot/A0A7I7JG80 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS20275 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUR4 ^@ Similarity ^@ Belongs to the 6-phosphogluconate dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS02050 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHH0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class II subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. http://togogenome.org/gene/2492438:G6N19_RS18280 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS02770 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJN7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS03120 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2492438:G6N19_RS07990 ^@ http://purl.uniprot.org/uniprot/A0A7I7JKU3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily.|||Homodimer.|||Probable oxidase that might be involved in lipid metabolism. http://togogenome.org/gene/2492438:G6N19_RS02755 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJW1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS18590 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS24 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS11115 ^@ http://purl.uniprot.org/uniprot/A0A7I7JP28 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/2492438:G6N19_RS11170 ^@ http://purl.uniprot.org/uniprot/A0A7I7JP40 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2492438:G6N19_RS13675 ^@ http://purl.uniprot.org/uniprot/A0A7I7JP48 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2492438:G6N19_RS12885 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQ08 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2492438:G6N19_RS10955 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMK8 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine. http://togogenome.org/gene/2492438:G6N19_RS17025 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSV8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/2492438:G6N19_RS09605 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLT3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2492438:G6N19_RS17015 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTF6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/2492438:G6N19_RS02395 ^@ http://purl.uniprot.org/uniprot/A0A7I7JK90 ^@ Similarity ^@ Belongs to the AccD/PCCB family. http://togogenome.org/gene/2492438:G6N19_RS02180 ^@ http://purl.uniprot.org/uniprot/A0A7I7JI03 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/2492438:G6N19_RS03165 ^@ http://purl.uniprot.org/uniprot/A0A7I7JII8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer.|||In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.|||In the N-terminal section; belongs to the MIP18 family. http://togogenome.org/gene/2492438:G6N19_RS12735 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPY1 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS16435 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQX5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS12430 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNG0 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/2492438:G6N19_RS09225 ^@ http://purl.uniprot.org/uniprot/A0A7I7JN38 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2492438:G6N19_RS14525 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRE2 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/2492438:G6N19_RS15150 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRV3 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/2492438:G6N19_RS10730 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMG3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/2492438:G6N19_RS07035 ^@ http://purl.uniprot.org/uniprot/A0A7I7JM53 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family.|||Binds 1 copper ion per subunit.|||Binds 1 zinc ion per subunit.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May play a role in favoring mycobacterial survival in phagocytes. http://togogenome.org/gene/2492438:G6N19_RS17445 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSX1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/2492438:G6N19_RS00110 ^@ http://purl.uniprot.org/uniprot/A0A7I7JG71 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/2492438:G6N19_RS13600 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRK1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/2492438:G6N19_RS20550 ^@ http://purl.uniprot.org/uniprot/A0A7I7JUY5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/2492438:G6N19_RS11555 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMZ8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/2492438:G6N19_RS18365 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTN9 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/2492438:G6N19_RS12360 ^@ http://purl.uniprot.org/uniprot/A0A7I7JQW9 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/2492438:G6N19_RS18895 ^@ http://purl.uniprot.org/uniprot/A0A7I7JTQ9 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/2492438:G6N19_RS15950 ^@ http://purl.uniprot.org/uniprot/A0A7I7JS12 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/2492438:G6N19_RS10160 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMD6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/2492438:G6N19_RS20460 ^@ http://purl.uniprot.org/uniprot/A0A7I7JVB1 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/2492438:G6N19_RS07260 ^@ http://purl.uniprot.org/uniprot/A0A7I7JM25 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/2492438:G6N19_RS03430 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS12325 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNE7 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/2492438:G6N19_RS16265 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSH6 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS12435 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the encapsulin family. Family 1 subfamily.|||Encapsulin nanocompartment http://togogenome.org/gene/2492438:G6N19_RS17580 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRC9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2492438:G6N19_RS17730 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/2492438:G6N19_RS14220 ^@ http://purl.uniprot.org/uniprot/A0A7I7JPS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS14025 ^@ http://purl.uniprot.org/uniprot/A0A7I7JR47 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS03825 ^@ http://purl.uniprot.org/uniprot/A0A7I7JID8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2492438:G6N19_RS01830 ^@ http://purl.uniprot.org/uniprot/A0A7I7JJZ1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS00830 ^@ http://purl.uniprot.org/uniprot/A0A7I7JHX5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with subunits I, II and III to form cytochrome c oxidase.|||Belongs to the cytochrome c oxidase bacterial subunit CtaF family.|||Cell membrane|||Membrane|||Part of cytochrome c oxidase, its function is unknown. http://togogenome.org/gene/2492438:G6N19_RS11695 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNF3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2492438:G6N19_RS18245 ^@ http://purl.uniprot.org/uniprot/A0A7I7JRQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Belongs to the peptidase S8 family.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS13070 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNS9 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/2492438:G6N19_RS08120 ^@ http://purl.uniprot.org/uniprot/A0A7I7JMU7 ^@ Similarity ^@ Belongs to the arylamine N-acetyltransferase family. http://togogenome.org/gene/2492438:G6N19_RS06985 ^@ http://purl.uniprot.org/uniprot/A0A7I7JM46 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2492438:G6N19_RS08795 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EccB family.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS19720 ^@ http://purl.uniprot.org/uniprot/A0A7I7JSY1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2492438:G6N19_RS02650 ^@ http://purl.uniprot.org/uniprot/A0A7I7JI83 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NucS endonuclease family.|||Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.|||Cytoplasm http://togogenome.org/gene/2492438:G6N19_RS11545 ^@ http://purl.uniprot.org/uniprot/A0A7I7JNB6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2492438:G6N19_RS04855 ^@ http://purl.uniprot.org/uniprot/A0A7I7JLM9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrcB (TC 9.B.71) family.|||Cell membrane|||Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane http://togogenome.org/gene/2492438:G6N19_RS20220 ^@ http://purl.uniprot.org/uniprot/A0A7I7JT81 ^@ Subcellular Location Annotation ^@ Membrane