http://togogenome.org/gene/2024526:LXD69_RS10495 ^@ http://purl.uniprot.org/uniprot/A0A8T9UGU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/2024526:LXD69_RS03950 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9C0 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidine kinase family.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS17950 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCJ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS17840 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9J4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS03290 ^@ http://purl.uniprot.org/uniprot/A0A8T9UF70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS03765 ^@ http://purl.uniprot.org/uniprot/A0A8T9UE86 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/2024526:LXD69_RS01420 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBE5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS15875 ^@ http://purl.uniprot.org/uniprot/A0A8T9U716 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MobA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.|||Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. http://togogenome.org/gene/2024526:LXD69_RS14390 ^@ http://purl.uniprot.org/uniprot/A0A8T9UC15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS17175 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDC2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/2024526:LXD69_RS04060 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCS2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS12595 ^@ http://purl.uniprot.org/uniprot/A0A8T9UB16 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/2024526:LXD69_RS05600 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEK7 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/2024526:LXD69_RS12860 ^@ http://purl.uniprot.org/uniprot/A0A8T9U4N2 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/2024526:LXD69_RS15625 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9K7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0394 family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS12880 ^@ http://purl.uniprot.org/uniprot/A0A8T9U5T6 ^@ Similarity ^@ Belongs to the beta-class carbonic anhydrase family. http://togogenome.org/gene/2024526:LXD69_RS12575 ^@ http://purl.uniprot.org/uniprot/A0A8T9U5L4 ^@ Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. http://togogenome.org/gene/2024526:LXD69_RS08060 ^@ http://purl.uniprot.org/uniprot/A0A8T9UG35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2024526:LXD69_RS16540 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/2024526:LXD69_RS17150 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7S5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/2024526:LXD69_RS03865 ^@ http://purl.uniprot.org/uniprot/A0A8T9UF11 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FBPase class 1 family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS03225 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBK6 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS06110 ^@ http://purl.uniprot.org/uniprot/A0A8T9UFI4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/2024526:LXD69_RS06100 ^@ http://purl.uniprot.org/uniprot/A0A8T9UD49 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/2024526:LXD69_RS07750 ^@ http://purl.uniprot.org/uniprot/A0A8T9UGK9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/2024526:LXD69_RS09295 ^@ http://purl.uniprot.org/uniprot/A0A8T9U3P2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/2024526:LXD69_RS06645 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCP1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2024526:LXD69_RS00050 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDS1 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/2024526:LXD69_RS08580 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEX4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/2024526:LXD69_RS10425 ^@ http://purl.uniprot.org/uniprot/A0A8T9U6I9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2024526:LXD69_RS02170 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEQ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/2024526:LXD69_RS08035 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDC9 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). http://togogenome.org/gene/2024526:LXD69_RS13230 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7Z9 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/2024526:LXD69_RS12235 ^@ http://purl.uniprot.org/uniprot/A0A8T9U986 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/2024526:LXD69_RS16805 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8Y5 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/2024526:LXD69_RS07550 ^@ http://purl.uniprot.org/uniprot/A0A8T9UFB9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/2024526:LXD69_RS06665 ^@ http://purl.uniprot.org/uniprot/A0A8T9UGB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/2024526:LXD69_RS17540 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBU8 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/2024526:LXD69_RS16515 ^@ http://purl.uniprot.org/uniprot/A0A8T9U6J1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS01325 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8Z6 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. http://togogenome.org/gene/2024526:LXD69_RS07675 ^@ http://purl.uniprot.org/uniprot/A0A8T9UFT2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Binds a copper A center.|||Cell membrane|||Membrane|||Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). http://togogenome.org/gene/2024526:LXD69_RS14605 ^@ http://purl.uniprot.org/uniprot/A0A8T9U5L8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/2024526:LXD69_RS04055 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/2024526:LXD69_RS03790 ^@ http://purl.uniprot.org/uniprot/A0A8T9U996 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/2024526:LXD69_RS01155 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7W6 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/2024526:LXD69_RS16255 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBI2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/2024526:LXD69_RS02495 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDX7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NqrA family.|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/2024526:LXD69_RS00380 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8G4 ^@ Similarity ^@ Belongs to the PTPS family. QueD subfamily. http://togogenome.org/gene/2024526:LXD69_RS01450 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEF9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS01005 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7T0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/2024526:LXD69_RS14570 ^@ http://purl.uniprot.org/uniprot/A0A8T9U6E0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/2024526:LXD69_RS10525 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8F0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CutC family.|||Cytoplasm|||Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case. http://togogenome.org/gene/2024526:LXD69_RS17870 ^@ http://purl.uniprot.org/uniprot/A0A8T9U867 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/2024526:LXD69_RS10365 ^@ http://purl.uniprot.org/uniprot/A0A8T9U3B7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/2024526:LXD69_RS00330 ^@ http://purl.uniprot.org/uniprot/A0A8T9U938 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS00690 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS16025 ^@ http://purl.uniprot.org/uniprot/A0A8T9U741 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/2024526:LXD69_RS00125 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8B9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS01055 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7U2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS04345 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS00860 ^@ http://purl.uniprot.org/uniprot/A0A8T9UB28 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/2024526:LXD69_RS16825 ^@ http://purl.uniprot.org/uniprot/A0A8T9U6P1 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/2024526:LXD69_RS00920 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9F4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/2024526:LXD69_RS12360 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9A0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YejK family.|||nucleoid http://togogenome.org/gene/2024526:LXD69_RS09280 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7U1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/2024526:LXD69_RS00685 ^@ http://purl.uniprot.org/uniprot/A0A8T9UE26 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/2024526:LXD69_RS15105 ^@ http://purl.uniprot.org/uniprot/A0A8T9U6N5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS15800 ^@ http://purl.uniprot.org/uniprot/A0A8T9UB84 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2024526:LXD69_RS15840 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9P4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS09790 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9M9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase Y family.|||Cell membrane|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/2024526:LXD69_RS06690 ^@ http://purl.uniprot.org/uniprot/A0A8T9UE24 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/2024526:LXD69_RS00880 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBG0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/2024526:LXD69_RS14575 ^@ http://purl.uniprot.org/uniprot/A0A8T9U6W4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/2024526:LXD69_RS12190 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7H0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS06775 ^@ http://purl.uniprot.org/uniprot/A0A8T9UFQ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/2024526:LXD69_RS02200 ^@ http://purl.uniprot.org/uniprot/A0A8T9UA76 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/2024526:LXD69_RS17805 ^@ http://purl.uniprot.org/uniprot/A0A8T9U772 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/2024526:LXD69_RS16790 ^@ http://purl.uniprot.org/uniprot/A0A8T9U865 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/2024526:LXD69_RS16220 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9L9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS00130 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8Z5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS03220 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCP0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS13210 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBD4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/2024526:LXD69_RS06625 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAT4 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/2024526:LXD69_RS13125 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9P1 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/2024526:LXD69_RS00875 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCU4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/2024526:LXD69_RS11065 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAA1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/2024526:LXD69_RS10540 ^@ http://purl.uniprot.org/uniprot/A0A8T9U4E6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/2024526:LXD69_RS03660 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBT2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/2024526:LXD69_RS14190 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBW4 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/2024526:LXD69_RS00810 ^@ http://purl.uniprot.org/uniprot/A0A8T9UB20 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/2024526:LXD69_RS06325 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEV1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/2024526:LXD69_RS06800 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCS1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/2024526:LXD69_RS01275 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9M7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/2024526:LXD69_RS00995 ^@ http://purl.uniprot.org/uniprot/A0A8T9UE83 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/2024526:LXD69_RS01130 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCZ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/2024526:LXD69_RS15085 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAV0 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/2024526:LXD69_RS04985 ^@ http://purl.uniprot.org/uniprot/A0A8T9UD86 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/2024526:LXD69_RS09400 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7P6 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/2024526:LXD69_RS15350 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCG7 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/2024526:LXD69_RS06120 ^@ http://purl.uniprot.org/uniprot/A0A8T9UES6 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/2024526:LXD69_RS00965 ^@ http://purl.uniprot.org/uniprot/A0A8T9UB47 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/2024526:LXD69_RS10285 ^@ http://purl.uniprot.org/uniprot/A0A8T9U864 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2024526:LXD69_RS07760 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBE4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane|||Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. http://togogenome.org/gene/2024526:LXD69_RS02235 ^@ http://purl.uniprot.org/uniprot/A0A8T9UD69 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/2024526:LXD69_RS17485 ^@ http://purl.uniprot.org/uniprot/A0A8T9U714 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/2024526:LXD69_RS14060 ^@ http://purl.uniprot.org/uniprot/A0A8T9U6J3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS05395 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDF4 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/2024526:LXD69_RS00960 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCK9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/2024526:LXD69_RS11005 ^@ http://purl.uniprot.org/uniprot/A0A8T9U6U4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/2024526:LXD69_RS13655 ^@ http://purl.uniprot.org/uniprot/A0A8T9UA11 ^@ Similarity ^@ Belongs to the UPF0246 family. http://togogenome.org/gene/2024526:LXD69_RS06380 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDX4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/2024526:LXD69_RS03020 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCK4 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/2024526:LXD69_RS00515 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS15915 ^@ http://purl.uniprot.org/uniprot/A0A8T9UB13 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS07015 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEI8 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/2024526:LXD69_RS13110 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBC0 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/2024526:LXD69_RS14150 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8H1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2024526:LXD69_RS00430 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAU9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Forms a complex with TatA.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. http://togogenome.org/gene/2024526:LXD69_RS00975 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9G6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/2024526:LXD69_RS05225 ^@ http://purl.uniprot.org/uniprot/A0A8T9UA24 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/2024526:LXD69_RS10510 ^@ http://purl.uniprot.org/uniprot/A0A8T9UA06 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/2024526:LXD69_RS10330 ^@ http://purl.uniprot.org/uniprot/A0A8T9U4A5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/2024526:LXD69_RS12230 ^@ http://purl.uniprot.org/uniprot/A0A8T9U4B9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/2024526:LXD69_RS10585 ^@ http://purl.uniprot.org/uniprot/A0A8T9U423 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/2024526:LXD69_RS10355 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9X6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS04970 ^@ http://purl.uniprot.org/uniprot/A0A8T9UF35 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/2024526:LXD69_RS03900 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9B4 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/2024526:LXD69_RS11210 ^@ http://purl.uniprot.org/uniprot/A0A8T9U5J5 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/2024526:LXD69_RS07685 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDZ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/2024526:LXD69_RS09265 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9D3 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/2024526:LXD69_RS06480 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDY9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Catalyzes the reversible hydration of fumarate to (S)-malate.|||Homodimer. http://togogenome.org/gene/2024526:LXD69_RS11195 ^@ http://purl.uniprot.org/uniprot/A0A8T9U4T3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS14185 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7D5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/2024526:LXD69_RS03635 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCI9 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/2024526:LXD69_RS03960 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCQ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS00950 ^@ http://purl.uniprot.org/uniprot/A0A8T9UD43 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2024526:LXD69_RS07095 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS04415 ^@ http://purl.uniprot.org/uniprot/A0A8T9UET1 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/2024526:LXD69_RS06460 ^@ http://purl.uniprot.org/uniprot/A0A8T9UG93 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/2024526:LXD69_RS14920 ^@ http://purl.uniprot.org/uniprot/A0A8T9U983 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2024526:LXD69_RS05515 ^@ http://purl.uniprot.org/uniprot/A0A8T9UF07 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/2024526:LXD69_RS12310 ^@ http://purl.uniprot.org/uniprot/A0A8T9U990 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/2024526:LXD69_RS15620 ^@ http://purl.uniprot.org/uniprot/A0A8T9UB19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0394 family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS05615 ^@ http://purl.uniprot.org/uniprot/A0A8T9UC45 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS07630 ^@ http://purl.uniprot.org/uniprot/A0A8T9UES9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/2024526:LXD69_RS09220 ^@ http://purl.uniprot.org/uniprot/A0A8T9U3B3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/2024526:LXD69_RS17580 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCC0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/2024526:LXD69_RS00425 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEK4 ^@ Similarity ^@ Belongs to the SIS family. GutQ/KpsF subfamily. http://togogenome.org/gene/2024526:LXD69_RS01655 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEI7 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/2024526:LXD69_RS00940 ^@ http://purl.uniprot.org/uniprot/A0A8T9UA71 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/2024526:LXD69_RS14845 ^@ http://purl.uniprot.org/uniprot/A0A8T9U6I5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/2024526:LXD69_RS09755 ^@ http://purl.uniprot.org/uniprot/A0A8T9U818 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/2024526:LXD69_RS17115 ^@ http://purl.uniprot.org/uniprot/A0A8T9U939 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/2024526:LXD69_RS07545 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBA7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/2024526:LXD69_RS08325 ^@ http://purl.uniprot.org/uniprot/A0A8T9UET7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/2024526:LXD69_RS11850 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8W9 ^@ Similarity ^@ Belongs to the SAM hydrolase / SAM-dependent halogenase family. http://togogenome.org/gene/2024526:LXD69_RS08885 ^@ http://purl.uniprot.org/uniprot/A0A8T9U459 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS01895 ^@ http://purl.uniprot.org/uniprot/A0A8T9UC22 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/2024526:LXD69_RS06125 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDT1 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS10620 ^@ http://purl.uniprot.org/uniprot/A0A8T9U3G7 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/2024526:LXD69_RS05640 ^@ http://purl.uniprot.org/uniprot/A0A8T9UFD6 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/2024526:LXD69_RS04450 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDA8 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/2024526:LXD69_RS10925 ^@ http://purl.uniprot.org/uniprot/A0A8T9U5D5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS03940 ^@ http://purl.uniprot.org/uniprot/A0A8T9UFE3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS07680 ^@ http://purl.uniprot.org/uniprot/A0A8T9UET9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS01035 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBI9 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/2024526:LXD69_RS17615 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8N6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.|||Cytoplasm http://togogenome.org/gene/2024526:LXD69_RS01455 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDE3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS01190 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAD0 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/2024526:LXD69_RS09370 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7H3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2024526:LXD69_RS16135 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBB8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/2024526:LXD69_RS14115 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAA4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS04595 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEM1 ^@ Similarity ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/2024526:LXD69_RS15100 ^@ http://purl.uniprot.org/uniprot/A0A8T9U902 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/2024526:LXD69_RS13105 ^@ http://purl.uniprot.org/uniprot/A0A8T9U6P5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS05175 ^@ http://purl.uniprot.org/uniprot/A0A8T9UA14 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/2024526:LXD69_RS05100 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEU8 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/2024526:LXD69_RS14795 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAN8 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/2024526:LXD69_RS08865 ^@ http://purl.uniprot.org/uniprot/A0A8T9U341 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS12870 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7T7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS12165 ^@ http://purl.uniprot.org/uniprot/A0A8T9U649 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS16510 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBN8 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/2024526:LXD69_RS04155 ^@ http://purl.uniprot.org/uniprot/A0A8T9UC14 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/2024526:LXD69_RS11415 ^@ http://purl.uniprot.org/uniprot/A0A8T9U5P5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS09450 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7Q5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/2024526:LXD69_RS07695 ^@ http://purl.uniprot.org/uniprot/A0A8T9UFZ2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueG family.|||Binds 2 [4Fe-4S] clusters per monomer.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/2024526:LXD69_RS09705 ^@ http://purl.uniprot.org/uniprot/A0A8T9U657 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/2024526:LXD69_RS07985 ^@ http://purl.uniprot.org/uniprot/A0A8T9UFW7 ^@ Similarity ^@ Belongs to the SusD family. http://togogenome.org/gene/2024526:LXD69_RS09260 ^@ http://purl.uniprot.org/uniprot/A0A8T9U4E9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/2024526:LXD69_RS07105 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS00910 ^@ http://purl.uniprot.org/uniprot/A0A8T9UB39 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/2024526:LXD69_RS06815 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDK2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell inner membrane|||Membrane|||Required for cell division and gliding motility. http://togogenome.org/gene/2024526:LXD69_RS06545 ^@ http://purl.uniprot.org/uniprot/A0A8T9UFF7 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/2024526:LXD69_RS01995 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDF1 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/2024526:LXD69_RS07570 ^@ http://purl.uniprot.org/uniprot/A0A8T9UFS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS11840 ^@ http://purl.uniprot.org/uniprot/A0A8T9U5Y5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS09855 ^@ http://purl.uniprot.org/uniprot/A0A8T9U835 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/2024526:LXD69_RS00855 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCJ1 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/2024526:LXD69_RS04080 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEE3 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/2024526:LXD69_RS14005 ^@ http://purl.uniprot.org/uniprot/A0A8T9U616 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/2024526:LXD69_RS03785 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEG8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/2024526:LXD69_RS04465 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEU6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/2024526:LXD69_RS03295 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS15250 ^@ http://purl.uniprot.org/uniprot/A0A8T9U935 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/2024526:LXD69_RS00775 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCS5 ^@ Similarity ^@ Belongs to the PAPS reductase family. CysD subfamily. http://togogenome.org/gene/2024526:LXD69_RS02645 ^@ http://purl.uniprot.org/uniprot/A0A8T9UE04 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/2024526:LXD69_RS00945 ^@ http://purl.uniprot.org/uniprot/A0A8T9UE73 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/2024526:LXD69_RS14895 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8W1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS10840 ^@ http://purl.uniprot.org/uniprot/A0A8T9U4L6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2024526:LXD69_RS04130 ^@ http://purl.uniprot.org/uniprot/A0A8T9UB98 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/2024526:LXD69_RS09845 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7Q9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL31 family. http://togogenome.org/gene/2024526:LXD69_RS07780 ^@ http://purl.uniprot.org/uniprot/A0A8T9UD85 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS17445 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAA6 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/2024526:LXD69_RS07415 ^@ http://purl.uniprot.org/uniprot/A0A8T9UFQ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS05770 ^@ http://purl.uniprot.org/uniprot/A0A8T9UC76 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS01715 ^@ http://purl.uniprot.org/uniprot/A0A8T9U880 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/2024526:LXD69_RS10890 ^@ http://purl.uniprot.org/uniprot/A0A8T9UGC7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/2024526:LXD69_RS11135 ^@ http://purl.uniprot.org/uniprot/A0A8T9U6W3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/2024526:LXD69_RS05985 ^@ http://purl.uniprot.org/uniprot/A0A8T9UF74 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS11830 ^@ http://purl.uniprot.org/uniprot/A0A8T9U900 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/2024526:LXD69_RS05720 ^@ http://purl.uniprot.org/uniprot/A0A8T9UF40 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/2024526:LXD69_RS02665 ^@ http://purl.uniprot.org/uniprot/A0A8T9UC30 ^@ Function|||Similarity ^@ Belongs to the peptidase S46 family.|||Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. http://togogenome.org/gene/2024526:LXD69_RS06405 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDB4 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/2024526:LXD69_RS06230 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDU6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS10640 ^@ http://purl.uniprot.org/uniprot/A0A8T9U4G7 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/2024526:LXD69_RS02480 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCB8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||Membrane|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/2024526:LXD69_RS10590 ^@ http://purl.uniprot.org/uniprot/A0A8T9U4F5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/2024526:LXD69_RS12175 ^@ http://purl.uniprot.org/uniprot/A0A8T9U929 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/2024526:LXD69_RS03025 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBG3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS06755 ^@ http://purl.uniprot.org/uniprot/A0A8T9UFI2 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/2024526:LXD69_RS11870 ^@ http://purl.uniprot.org/uniprot/A0A8T9U4R3 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/2024526:LXD69_RS12050 ^@ http://purl.uniprot.org/uniprot/A0A8T9U599 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/2024526:LXD69_RS11280 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8S8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/2024526:LXD69_RS07025 ^@ http://purl.uniprot.org/uniprot/A0A8T9UGF0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/2024526:LXD69_RS06895 ^@ http://purl.uniprot.org/uniprot/A0A8T9UE58 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/2024526:LXD69_RS01000 ^@ http://purl.uniprot.org/uniprot/A0A8T9UD52 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/2024526:LXD69_RS09270 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7F3 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/2024526:LXD69_RS00475 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCC4 ^@ Similarity ^@ Belongs to the sterol desaturase family. http://togogenome.org/gene/2024526:LXD69_RS07555 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEG1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/2024526:LXD69_RS09060 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7R0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/2024526:LXD69_RS03005 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9U6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/2024526:LXD69_RS04955 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDQ4 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/2024526:LXD69_RS06375 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEV7 ^@ Similarity ^@ Belongs to the ATPase epsilon chain family. http://togogenome.org/gene/2024526:LXD69_RS10920 ^@ http://purl.uniprot.org/uniprot/A0A8T9U735 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS04960 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCH9 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/2024526:LXD69_RS12055 ^@ http://purl.uniprot.org/uniprot/A0A8T9U937 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 3 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/2024526:LXD69_RS10490 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8A5 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/2024526:LXD69_RS00120 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAN6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/2024526:LXD69_RS03850 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDV3 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/2024526:LXD69_RS00890 ^@ http://purl.uniprot.org/uniprot/A0A8T9UE65 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2024526:LXD69_RS13525 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9W9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/2024526:LXD69_RS07615 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCC3 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/2024526:LXD69_RS12700 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9E8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/2024526:LXD69_RS03320 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAT9 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/2024526:LXD69_RS12875 ^@ http://purl.uniprot.org/uniprot/A0A8T9U5D6 ^@ Similarity ^@ Belongs to the beta-class carbonic anhydrase family. http://togogenome.org/gene/2024526:LXD69_RS06995 ^@ http://purl.uniprot.org/uniprot/A0A8T9UE88 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer.|||In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.|||In the N-terminal section; belongs to the MIP18 family. http://togogenome.org/gene/2024526:LXD69_RS06575 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEY4 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/2024526:LXD69_RS11060 ^@ http://purl.uniprot.org/uniprot/A0A8T9U5F7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/2024526:LXD69_RS11055 ^@ http://purl.uniprot.org/uniprot/A0A8T9U755 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/2024526:LXD69_RS17900 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCI3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS00385 ^@ http://purl.uniprot.org/uniprot/A0A8T9U948 ^@ Similarity ^@ Belongs to the IPP isomerase type 1 family. http://togogenome.org/gene/2024526:LXD69_RS14590 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7M0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/2024526:LXD69_RS00115 ^@ http://purl.uniprot.org/uniprot/A0A8T9UC57 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/2024526:LXD69_RS14160 ^@ http://purl.uniprot.org/uniprot/A0A8T9U6L5 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS15210 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7A5 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/2024526:LXD69_RS07895 ^@ http://purl.uniprot.org/uniprot/A0A8T9UE29 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/2024526:LXD69_RS08310 ^@ http://purl.uniprot.org/uniprot/A0A8T9UG60 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. http://togogenome.org/gene/2024526:LXD69_RS06680 ^@ http://purl.uniprot.org/uniprot/A0A8T9UF02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS12435 ^@ http://purl.uniprot.org/uniprot/A0A8T9UFA4 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/2024526:LXD69_RS15790 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCN4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/2024526:LXD69_RS10300 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9X0 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/2024526:LXD69_RS02255 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDJ5 ^@ Similarity ^@ Belongs to the NAD synthetase family. http://togogenome.org/gene/2024526:LXD69_RS07905 ^@ http://purl.uniprot.org/uniprot/A0A8T9UG15 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS02285 ^@ http://purl.uniprot.org/uniprot/A0A8T9UD77 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2024526:LXD69_RS02860 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAI7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/2024526:LXD69_RS07735 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEU9 ^@ Similarity ^@ In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the malic enzymes family. http://togogenome.org/gene/2024526:LXD69_RS03015 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDV8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS08555 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEC1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/2024526:LXD69_RS01395 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAH3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS01370 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/2024526:LXD69_RS15095 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAN0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/2024526:LXD69_RS12315 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7V2 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/2024526:LXD69_RS08730 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBW5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/2024526:LXD69_RS09360 ^@ http://purl.uniprot.org/uniprot/A0A8T9U4H1 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/2024526:LXD69_RS13475 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9V6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS11205 ^@ http://purl.uniprot.org/uniprot/A0A8T9U786 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2024526:LXD69_RS07625 ^@ http://purl.uniprot.org/uniprot/A0A8T9UFS8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/2024526:LXD69_RS12105 ^@ http://purl.uniprot.org/uniprot/A0A8T9U946 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/2024526:LXD69_RS09130 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7J2 ^@ Subcellular Location Annotation ^@ Periplasm http://togogenome.org/gene/2024526:LXD69_RS03190 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8Z1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/2024526:LXD69_RS10635 ^@ http://purl.uniprot.org/uniprot/A0A8T9U437 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/2024526:LXD69_RS08695 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDN0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/2024526:LXD69_RS16320 ^@ http://purl.uniprot.org/uniprot/A0A8T9UB90 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/2024526:LXD69_RS00900 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7R1 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/2024526:LXD69_RS01305 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7Z3 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/2024526:LXD69_RS08820 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEG2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/2024526:LXD69_RS00865 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8P5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/2024526:LXD69_RS13220 ^@ http://purl.uniprot.org/uniprot/A0A8T9U4V1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/2024526:LXD69_RS00990 ^@ http://purl.uniprot.org/uniprot/A0A8T9UA88 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/2024526:LXD69_RS01280 ^@ http://purl.uniprot.org/uniprot/A0A8T9UD31 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/2024526:LXD69_RS15985 ^@ http://purl.uniprot.org/uniprot/A0A8T9UB86 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/2024526:LXD69_RS14760 ^@ http://purl.uniprot.org/uniprot/A0A8T9UC74 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/2024526:LXD69_RS05690 ^@ http://purl.uniprot.org/uniprot/A0A8T9UFE2 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/2024526:LXD69_RS13805 ^@ http://purl.uniprot.org/uniprot/A0A8T9U6D2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS07055 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCW7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/2024526:LXD69_RS03345 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEB0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/2024526:LXD69_RS04095 ^@ http://purl.uniprot.org/uniprot/A0A8T9UFG4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/2024526:LXD69_RS00980 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCW4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2024526:LXD69_RS04085 ^@ http://purl.uniprot.org/uniprot/A0A8T9UD47 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/2024526:LXD69_RS14880 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAQ7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/2024526:LXD69_RS11100 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8K9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/2024526:LXD69_RS09740 ^@ http://purl.uniprot.org/uniprot/A0A8T9UF98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/2024526:LXD69_RS05725 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDX3 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/2024526:LXD69_RS16335 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7W4 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/2024526:LXD69_RS08575 ^@ http://purl.uniprot.org/uniprot/A0A8T9UFL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/2024526:LXD69_RS11445 ^@ http://purl.uniprot.org/uniprot/A0A8T9U4I6 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/2024526:LXD69_RS07655 ^@ http://purl.uniprot.org/uniprot/A0A8T9UFD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS09775 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7X2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/2024526:LXD69_RS09700 ^@ http://purl.uniprot.org/uniprot/A0A8T9U810 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/2024526:LXD69_RS17990 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9M6 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/2024526:LXD69_RS00935 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBG7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/2024526:LXD69_RS09350 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7N6 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/2024526:LXD69_RS07440 ^@ http://purl.uniprot.org/uniprot/A0A8T9UB88 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/2024526:LXD69_RS09285 ^@ http://purl.uniprot.org/uniprot/A0A8T9U5Y2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/2024526:LXD69_RS03505 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCU1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/2024526:LXD69_RS00885 ^@ http://purl.uniprot.org/uniprot/A0A8T9UA64 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/2024526:LXD69_RS03185 ^@ http://purl.uniprot.org/uniprot/A0A8T9UE90 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/2024526:LXD69_RS07430 ^@ http://purl.uniprot.org/uniprot/A0A8T9UGI1 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/2024526:LXD69_RS06085 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCD5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/2024526:LXD69_RS06335 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBM6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/2024526:LXD69_RS08915 ^@ http://purl.uniprot.org/uniprot/A0A8T9U354 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS03725 ^@ http://purl.uniprot.org/uniprot/A0A8T9U984 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/2024526:LXD69_RS10940 ^@ http://purl.uniprot.org/uniprot/A0A8T9U3M4 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/2024526:LXD69_RS06490 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCL1 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/2024526:LXD69_RS00955 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7S0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/2024526:LXD69_RS09425 ^@ http://purl.uniprot.org/uniprot/A0A8T9U2V6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS16205 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBH0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/2024526:LXD69_RS06650 ^@ http://purl.uniprot.org/uniprot/A0A8T9UFG5 ^@ Similarity ^@ Belongs to the sigma-54 factor family. http://togogenome.org/gene/2024526:LXD69_RS06435 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBP7 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/2024526:LXD69_RS17180 ^@ http://purl.uniprot.org/uniprot/A0A8T9UC36 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/2024526:LXD69_RS01870 ^@ http://purl.uniprot.org/uniprot/A0A8T9UD13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/2024526:LXD69_RS09325 ^@ http://purl.uniprot.org/uniprot/A0A8T9U2S9 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/2024526:LXD69_RS00005 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCK5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/2024526:LXD69_RS15980 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7P3 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/2024526:LXD69_RS00110 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7C1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/2024526:LXD69_RS00040 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAZ4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS09250 ^@ http://purl.uniprot.org/uniprot/A0A8T9U671 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/2024526:LXD69_RS08830 ^@ http://purl.uniprot.org/uniprot/A0A8T9UGB8 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/2024526:LXD69_RS04600 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS03820 ^@ http://purl.uniprot.org/uniprot/A0A8T9UE94 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. http://togogenome.org/gene/2024526:LXD69_RS05925 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS02410 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBY3 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/2024526:LXD69_RS06455 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDC6 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit A family. http://togogenome.org/gene/2024526:LXD69_RS13560 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8J0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS04940 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBQ9 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/2024526:LXD69_RS06945 ^@ http://purl.uniprot.org/uniprot/A0A8T9UE68 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS13495 ^@ http://purl.uniprot.org/uniprot/A0A8T9U5R2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS03300 ^@ http://purl.uniprot.org/uniprot/A0A8T9U911 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/2024526:LXD69_RS17865 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAI2 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/2024526:LXD69_RS07790 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS00970 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8R3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/2024526:LXD69_RS09735 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9M1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS02715 ^@ http://purl.uniprot.org/uniprot/A0A8T9UGE8 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/2024526:LXD69_RS17155 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8D5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS03580 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDR8 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/2024526:LXD69_RS01240 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAD9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2024526:LXD69_RS14140 ^@ http://purl.uniprot.org/uniprot/A0A8T9U5C3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/2024526:LXD69_RS08010 ^@ http://purl.uniprot.org/uniprot/A0A8T9UG28 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS03640 ^@ http://purl.uniprot.org/uniprot/A0A8T9UA58 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/2024526:LXD69_RS15845 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8B3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS08300 ^@ http://purl.uniprot.org/uniprot/A0A8T9UE85 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/2024526:LXD69_RS00870 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9D9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/2024526:LXD69_RS05275 ^@ http://purl.uniprot.org/uniprot/A0A8T9UF79 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/2024526:LXD69_RS06205 ^@ http://purl.uniprot.org/uniprot/A0A8T9UG59 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/2024526:LXD69_RS07795 ^@ http://purl.uniprot.org/uniprot/A0A8T9UE17 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS12305 ^@ http://purl.uniprot.org/uniprot/A0A8T9U5F2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/2024526:LXD69_RS01400 ^@ http://purl.uniprot.org/uniprot/A0A8T9UEF2 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/2024526:LXD69_RS11000 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8N1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/2024526:LXD69_RS16815 ^@ http://purl.uniprot.org/uniprot/A0A8T9UD16 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/2024526:LXD69_RS05900 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAE7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/2024526:LXD69_RS03045 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDJ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS08385 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCQ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS11965 ^@ http://purl.uniprot.org/uniprot/A0A8T9U604 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS16820 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBW3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/2024526:LXD69_RS07005 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCV8 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the ferredoxin--NADP reductase type 2 family.|||Binds 1 FAD per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS06780 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAW8 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/2024526:LXD69_RS09275 ^@ http://purl.uniprot.org/uniprot/A0A8T9U2S1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/2024526:LXD69_RS14625 ^@ http://purl.uniprot.org/uniprot/A0A8T9U6Y1 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/2024526:LXD69_RS00925 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCV5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/2024526:LXD69_RS00420 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCB4 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/2024526:LXD69_RS02015 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDQ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS15265 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAW5 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/2024526:LXD69_RS02070 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8E0 ^@ Similarity ^@ Belongs to the DNase I family. http://togogenome.org/gene/2024526:LXD69_RS14600 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAK0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxC family.|||Belongs to the thioester dehydratase family. FabZ subfamily.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/2024526:LXD69_RS03655 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCX0 ^@ Similarity ^@ Belongs to the PAPS reductase family. CysD subfamily. http://togogenome.org/gene/2024526:LXD69_RS05780 ^@ http://purl.uniprot.org/uniprot/A0A8T9UDY1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/2024526:LXD69_RS15360 ^@ http://purl.uniprot.org/uniprot/A0A8T9U5Y8 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/2024526:LXD69_RS07825 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCF6 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/2024526:LXD69_RS08015 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBI3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/2024526:LXD69_RS08690 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCV4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/2024526:LXD69_RS03830 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/2024526:LXD69_RS07560 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCB3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/2024526:LXD69_RS16275 ^@ http://purl.uniprot.org/uniprot/A0A8T9U795 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/2024526:LXD69_RS02470 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAB9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrF family.|||Binds 1 [2Fe-2S] cluster.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway. http://togogenome.org/gene/2024526:LXD69_RS04890 ^@ http://purl.uniprot.org/uniprot/A0A8T9UBP6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 3-HAO family.|||Binds 2 Fe(2+) ions per subunit.|||Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. http://togogenome.org/gene/2024526:LXD69_RS03540 ^@ http://purl.uniprot.org/uniprot/A0A8T9UA38 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/2024526:LXD69_RS16710 ^@ http://purl.uniprot.org/uniprot/A0A8T9UD48 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/2024526:LXD69_RS14840 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8V3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/2024526:LXD69_RS17215 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAG3 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/2024526:LXD69_RS04255 ^@ http://purl.uniprot.org/uniprot/A0A8T9UC32 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/2024526:LXD69_RS02890 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8T3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/2024526:LXD69_RS00905 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCJ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/2024526:LXD69_RS00895 ^@ http://purl.uniprot.org/uniprot/A0A8T9UD33 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/2024526:LXD69_RS03255 ^@ http://purl.uniprot.org/uniprot/A0A8T9UCC8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/2024526:LXD69_RS14865 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7S6 ^@ Similarity|||Subunit ^@ Belongs to the KdsC family.|||Homotetramer. http://togogenome.org/gene/2024526:LXD69_RS14995 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/2024526:LXD69_RS00915 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8Q4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/2024526:LXD69_RS10310 ^@ http://purl.uniprot.org/uniprot/A0A8T9U3A7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/2024526:LXD69_RS15270 ^@ http://purl.uniprot.org/uniprot/A0A8T9U9F1 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/2024526:LXD69_RS09290 ^@ http://purl.uniprot.org/uniprot/A0A8T9U3C4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/2024526:LXD69_RS10935 ^@ http://purl.uniprot.org/uniprot/A0A8T9U8C7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/2024526:LXD69_RS12925 ^@ http://purl.uniprot.org/uniprot/A0A8T9U5E6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/2024526:LXD69_RS11865 ^@ http://purl.uniprot.org/uniprot/A0A8T9U7A7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/2024526:LXD69_RS12170 ^@ http://purl.uniprot.org/uniprot/A0A8T9UAU1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/2024526:LXD69_RS03515 ^@ http://purl.uniprot.org/uniprot/A0A8T9UF94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/2024526:LXD69_RS14450 ^@ http://purl.uniprot.org/uniprot/A0A8T9U5J3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane