http://togogenome.org/gene/1969:CP983_RS22485 ^@ http://purl.uniprot.org/uniprot/A0A7H8TAH5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1969:CP983_RS12715 ^@ http://purl.uniprot.org/uniprot/A0A7H8T4Q5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1969:CP983_RS26535 ^@ http://purl.uniprot.org/uniprot/A0A7H8TCE1 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1969:CP983_RS32755 ^@ http://purl.uniprot.org/uniprot/A0A7H8TFS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/1969:CP983_RS27370 ^@ http://purl.uniprot.org/uniprot/A0A7H8TCZ2 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1969:CP983_RS21695 ^@ http://purl.uniprot.org/uniprot/A0A7H8TB26 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/1969:CP983_RS35905 ^@ http://purl.uniprot.org/uniprot/A0A8E3QH64 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/1969:CP983_RS02390 ^@ http://purl.uniprot.org/uniprot/A0A7H8SZ64 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1969:CP983_RS31930 ^@ http://purl.uniprot.org/uniprot/A0A7H8TFM5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/1969:CP983_RS13965 ^@ http://purl.uniprot.org/uniprot/A0A7H8T6V9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/1969:CP983_RS15210 ^@ http://purl.uniprot.org/uniprot/A0A7H8T662 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1969:CP983_RS31340 ^@ http://purl.uniprot.org/uniprot/A0A8E3Q2B8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/1969:CP983_RS19795 ^@ http://purl.uniprot.org/uniprot/A0A8E3TJU2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1969:CP983_RS29000 ^@ http://purl.uniprot.org/uniprot/A0A8E3TN84 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/1969:CP983_RS32970 ^@ http://purl.uniprot.org/uniprot/A0A7H8TNZ0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Membrane http://togogenome.org/gene/1969:CP983_RS32860 ^@ http://purl.uniprot.org/uniprot/A0A7H8TFT8 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1969:CP983_RS17370 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7E8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1969:CP983_RS09215 ^@ http://purl.uniprot.org/uniprot/A0A8E3Q3N5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Membrane http://togogenome.org/gene/1969:CP983_RS11870 ^@ http://purl.uniprot.org/uniprot/A0A7H8T5C3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1969:CP983_RS37260 ^@ http://purl.uniprot.org/uniprot/A0A7H8TI39 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1969:CP983_RS12555 ^@ http://purl.uniprot.org/uniprot/A0A7H8T4N1 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1969:CP983_RS17400 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7H8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1969:CP983_RS17030 ^@ http://purl.uniprot.org/uniprot/A0A7H8T8T1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1969:CP983_RS17375 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7E9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1969:CP983_RS12505 ^@ http://purl.uniprot.org/uniprot/A0A7H8T4Z8 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1969:CP983_RS21540 ^@ http://purl.uniprot.org/uniprot/A0A7H8TN57 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/1969:CP983_RS25805 ^@ http://purl.uniprot.org/uniprot/A0A7H8TC63 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1969:CP983_RS17215 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7L6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/1969:CP983_RS04790 ^@ http://purl.uniprot.org/uniprot/A0A7H8T1M0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1969:CP983_RS34920 ^@ http://purl.uniprot.org/uniprot/A0A7H8THA7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1969:CP983_RS35860 ^@ http://purl.uniprot.org/uniprot/A0A7H8TLI3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1969:CP983_RS13900 ^@ http://purl.uniprot.org/uniprot/A0A7H8T6V2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/1969:CP983_RS32840 ^@ http://purl.uniprot.org/uniprot/A0A7H8TG25 ^@ Function|||Similarity ^@ Belongs to the RapZ-like family.|||Displays ATPase and GTPase activities. http://togogenome.org/gene/1969:CP983_RS08280 ^@ http://purl.uniprot.org/uniprot/A0A8E3Q3C5 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. http://togogenome.org/gene/1969:CP983_RS12790 ^@ http://purl.uniprot.org/uniprot/A0A8E3PHT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/1969:CP983_RS32160 ^@ http://purl.uniprot.org/uniprot/A0A7H8TFG8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/1969:CP983_RS36395 ^@ http://purl.uniprot.org/uniprot/A0A7H8THP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sbp family.|||Cell membrane http://togogenome.org/gene/1969:CP983_RS41970 ^@ http://purl.uniprot.org/uniprot/A0A7H8TLT9 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/1969:CP983_RS12905 ^@ http://purl.uniprot.org/uniprot/A0A7H8T4R5 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1969:CP983_RS06390 ^@ http://purl.uniprot.org/uniprot/A0A8E3QAF8 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1969:CP983_RS26255 ^@ http://purl.uniprot.org/uniprot/A0A7H8TGJ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/1969:CP983_RS26095 ^@ http://purl.uniprot.org/uniprot/A0A7H8TC58 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1969:CP983_RS21685 ^@ http://purl.uniprot.org/uniprot/A0A7H8TDQ1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/1969:CP983_RS29715 ^@ http://purl.uniprot.org/uniprot/A0A7H8TFF1 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1969:CP983_RS18805 ^@ http://purl.uniprot.org/uniprot/A0A7H8T8C1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1969:CP983_RS23995 ^@ http://purl.uniprot.org/uniprot/A0A7H8TB31 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DtxR/MntR family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1969:CP983_RS35850 ^@ http://purl.uniprot.org/uniprot/A0A7H8TIQ6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS13 family. http://togogenome.org/gene/1969:CP983_RS23555 ^@ http://purl.uniprot.org/uniprot/A0A7H8TAW3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1969:CP983_RS19160 ^@ http://purl.uniprot.org/uniprot/A0A8E3TIE1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1969:CP983_RS30965 ^@ http://purl.uniprot.org/uniprot/A0A7H8TER4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1969:CP983_RS14465 ^@ http://purl.uniprot.org/uniprot/A0A7H8TAA9 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).|||Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1969:CP983_RS35050 ^@ http://purl.uniprot.org/uniprot/A0A7H8THK1 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1969:CP983_RS31745 ^@ http://purl.uniprot.org/uniprot/A0A7H8TGH4 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Non-allosteric. http://togogenome.org/gene/1969:CP983_RS26675 ^@ http://purl.uniprot.org/uniprot/A0A7H8TDV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1969:CP983_RS32850 ^@ http://purl.uniprot.org/uniprot/A0A7H8TGB0 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/1969:CP983_RS30125 ^@ http://purl.uniprot.org/uniprot/A0A8E3Q1Z5 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/1969:CP983_RS08580 ^@ http://purl.uniprot.org/uniprot/A0A7H8T2L1 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/1969:CP983_RS35115 ^@ http://purl.uniprot.org/uniprot/A0A7H8THL1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1969:CP983_RS10395 ^@ http://purl.uniprot.org/uniprot/A0A7H8T3K8 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1969:CP983_RS36045 ^@ http://purl.uniprot.org/uniprot/A0A8E3QC69 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/1969:CP983_RS17365 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7U2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1969:CP983_RS26410 ^@ http://purl.uniprot.org/uniprot/A0A7H8TGM3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/1969:CP983_RS11910 ^@ http://purl.uniprot.org/uniprot/A0A7H8T8K3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1969:CP983_RS17220 ^@ http://purl.uniprot.org/uniprot/A0A7H8T8S7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1969:CP983_RS12760 ^@ http://purl.uniprot.org/uniprot/A0A7H8T612 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1969:CP983_RS17415 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7V0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/1969:CP983_RS17095 ^@ http://purl.uniprot.org/uniprot/A0A7H8T794 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1969:CP983_RS26745 ^@ http://purl.uniprot.org/uniprot/A0A7H8TCH5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/1969:CP983_RS19145 ^@ http://purl.uniprot.org/uniprot/A0A7H8T8B1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/1969:CP983_RS13380 ^@ http://purl.uniprot.org/uniprot/A0A7H8T583 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1969:CP983_RS28365 ^@ http://purl.uniprot.org/uniprot/A0A8E3Q9R5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1969:CP983_RS36300 ^@ http://purl.uniprot.org/uniprot/A0A7H8THV9 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1969:CP983_RS18785 ^@ http://purl.uniprot.org/uniprot/A0A7H8T8E1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the DisA family.|||Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.|||Homooctamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. http://togogenome.org/gene/1969:CP983_RS11415 ^@ http://purl.uniprot.org/uniprot/A0A7H8T4B4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1969:CP983_RS27850 ^@ http://purl.uniprot.org/uniprot/A0A8E3Q163 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VKOR family.|||Membrane http://togogenome.org/gene/1969:CP983_RS17325 ^@ http://purl.uniprot.org/uniprot/A0A7H8T8V1 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1969:CP983_RS23065 ^@ http://purl.uniprot.org/uniprot/A0A7H8TAJ5 ^@ Caution|||Similarity ^@ Belongs to the nitrobindin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Lacks the conserved His residue that binds heme iron in the nitrobindin family. http://togogenome.org/gene/1969:CP983_RS28955 ^@ http://purl.uniprot.org/uniprot/A0A7H8TE20 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1969:CP983_RS17390 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7H4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1969:CP983_RS17535 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7W9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/1969:CP983_RS25710 ^@ http://purl.uniprot.org/uniprot/A0A7H8TBV5 ^@ Similarity ^@ Belongs to the transglycosylase family. Rpf subfamily. http://togogenome.org/gene/1969:CP983_RS28710 ^@ http://purl.uniprot.org/uniprot/A0A7H8TDL3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1969:CP983_RS13180 ^@ http://purl.uniprot.org/uniprot/A0A7H8T6F2 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1969:CP983_RS12080 ^@ http://purl.uniprot.org/uniprot/A0A7H8T480 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/1969:CP983_RS40625 ^@ http://purl.uniprot.org/uniprot/A0A7H8TJB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1969:CP983_RS17405 ^@ http://purl.uniprot.org/uniprot/A0A7H8T901 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/1969:CP983_RS12085 ^@ http://purl.uniprot.org/uniprot/A0A7H8T8N3 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/1969:CP983_RS17275 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7C9 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1969:CP983_RS17280 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7M7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/1969:CP983_RS12595 ^@ http://purl.uniprot.org/uniprot/A0A7H8T4Q0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ A probable RNA-binding protein.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm http://togogenome.org/gene/1969:CP983_RS14440 ^@ http://purl.uniprot.org/uniprot/A0A7H8T5U7 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1969:CP983_RS25535 ^@ http://purl.uniprot.org/uniprot/A0A7H8TBS7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/1969:CP983_RS33455 ^@ http://purl.uniprot.org/uniprot/A0A7H8TG43 ^@ Function|||Similarity ^@ Belongs to the ectoine synthase family.|||Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant. http://togogenome.org/gene/1969:CP983_RS28790 ^@ http://purl.uniprot.org/uniprot/A0A7H8TE12 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/1969:CP983_RS29255 ^@ http://purl.uniprot.org/uniprot/A0A7H8TDV0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1969:CP983_RS21700 ^@ http://purl.uniprot.org/uniprot/A0A7H8T9J8 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/1969:CP983_RS19800 ^@ http://purl.uniprot.org/uniprot/A0A7H8T8T0 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine. http://togogenome.org/gene/1969:CP983_RS36050 ^@ http://purl.uniprot.org/uniprot/A0A7H8TI81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/1969:CP983_RS35725 ^@ http://purl.uniprot.org/uniprot/A0A7H8THJ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1969:CP983_RS17520 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7K0 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1969:CP983_RS26845 ^@ http://purl.uniprot.org/uniprot/A0A7H8TCJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1969:CP983_RS17470 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7W0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1969:CP983_RS17805 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7Z4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/1969:CP983_RS11545 ^@ http://purl.uniprot.org/uniprot/A0A7H8T3Y7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/1969:CP983_RS17455 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7I8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1969:CP983_RS35655 ^@ http://purl.uniprot.org/uniprot/A0A7H8TIM2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/1969:CP983_RS29560 ^@ http://purl.uniprot.org/uniprot/A0A8E3QHG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1969:CP983_RS25715 ^@ http://purl.uniprot.org/uniprot/A0A8E3TQY3 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1969:CP983_RS38475 ^@ http://purl.uniprot.org/uniprot/A0A7H8TQS2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ETF alpha-subunit/FixB family.|||Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/1969:CP983_RS31570 ^@ http://purl.uniprot.org/uniprot/A0A7H8TGF5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with subunits I, II and III to form cytochrome c oxidase.|||Belongs to the cytochrome c oxidase bacterial subunit CtaF family.|||Cell membrane|||Membrane|||Part of cytochrome c oxidase, its function is unknown. http://togogenome.org/gene/1969:CP983_RS34825 ^@ http://purl.uniprot.org/uniprot/A0A7H8TI65 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.|||Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.|||Homotetramer composed of a dimer of dimers. http://togogenome.org/gene/1969:CP983_RS12925 ^@ http://purl.uniprot.org/uniprot/A0A7H8T4S4 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1969:CP983_RS13750 ^@ http://purl.uniprot.org/uniprot/A0A7H8T6S3 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1969:CP983_RS29105 ^@ http://purl.uniprot.org/uniprot/A0A7H8TF76 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/1969:CP983_RS08685 ^@ http://purl.uniprot.org/uniprot/A0A7H8T2P2 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1969:CP983_RS41345 ^@ http://purl.uniprot.org/uniprot/A0A7H8TK03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1969:CP983_RS35320 ^@ http://purl.uniprot.org/uniprot/A0A7H8TIE0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1969:CP983_RS07560 ^@ http://purl.uniprot.org/uniprot/A0A8E3TGF6 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1969:CP983_RS17395 ^@ http://purl.uniprot.org/uniprot/A0A7H8TBU7 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1969:CP983_RS13815 ^@ http://purl.uniprot.org/uniprot/A0A7H8T5F5 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1969:CP983_RS14660 ^@ http://purl.uniprot.org/uniprot/A0A7H8T5Y2 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1969:CP983_RS36680 ^@ http://purl.uniprot.org/uniprot/A0A7H8TI78 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/1969:CP983_RS17500 ^@ http://purl.uniprot.org/uniprot/A0A7H8T8X8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1969:CP983_RS35520 ^@ http://purl.uniprot.org/uniprot/A0A7H8THR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SsgA family.|||Cell septum http://togogenome.org/gene/1969:CP983_RS35750 ^@ http://purl.uniprot.org/uniprot/A0A7H8TNR7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/1969:CP983_RS19855 ^@ http://purl.uniprot.org/uniprot/A0A8E3Q1M8 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/1969:CP983_RS30005 ^@ http://purl.uniprot.org/uniprot/A0A8E3PUW6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1969:CP983_RS19860 ^@ http://purl.uniprot.org/uniprot/A0A7H8T8U3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/1969:CP983_RS13805 ^@ http://purl.uniprot.org/uniprot/A0A7H8T5G6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NucS endonuclease family.|||Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.|||Cytoplasm http://togogenome.org/gene/1969:CP983_RS17350 ^@ http://purl.uniprot.org/uniprot/A0A7H8TRP2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1969:CP983_RS05195 ^@ http://purl.uniprot.org/uniprot/A0A7H8T591 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1969:CP983_RS19045 ^@ http://purl.uniprot.org/uniprot/A0A7H8TMX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/1969:CP983_RS08070 ^@ http://purl.uniprot.org/uniprot/A0A7H8T281 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gas vesicle protein type A family.|||Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.|||gas vesicle membrane http://togogenome.org/gene/1969:CP983_RS21675 ^@ http://purl.uniprot.org/uniprot/A0A8E3PKH1 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/1969:CP983_RS33075 ^@ http://purl.uniprot.org/uniprot/A0A8E3Q8X2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1969:CP983_RS17465 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7J9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1969:CP983_RS26340 ^@ http://purl.uniprot.org/uniprot/A0A7H8TCL0 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/1969:CP983_RS31765 ^@ http://purl.uniprot.org/uniprot/A0A8E3TM52 ^@ Similarity ^@ Belongs to the class-II DAHP synthase family. http://togogenome.org/gene/1969:CP983_RS32875 ^@ http://purl.uniprot.org/uniprot/A0A7H8TNN6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1969:CP983_RS43245 ^@ http://purl.uniprot.org/uniprot/A0A7H8TKK3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1969:CP983_RS26395 ^@ http://purl.uniprot.org/uniprot/A0A7H8TCL8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF2.|||Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. http://togogenome.org/gene/1969:CP983_RS36380 ^@ http://purl.uniprot.org/uniprot/A0A7H8THM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/1969:CP983_RS27355 ^@ http://purl.uniprot.org/uniprot/A0A8E3Q3W7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-to-5' exoribonuclease specific for small oligoribonucleotides.|||Belongs to the oligoribonuclease family.|||Cytoplasm http://togogenome.org/gene/1969:CP983_RS18915 ^@ http://purl.uniprot.org/uniprot/A0A7H8T869 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1969:CP983_RS13895 ^@ http://purl.uniprot.org/uniprot/A0A7H8T5I1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1969:CP983_RS15070 ^@ http://purl.uniprot.org/uniprot/A0A7H8T690 ^@ Cofactor|||Function ^@ Binds 1 [3Fe-4S] cluster.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1969:CP983_RS36160 ^@ http://purl.uniprot.org/uniprot/A0A7H8TIV6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase-binding protein RbpA family.|||Bind 1 Zn(2+) per subunit.|||Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.|||Forms a complex with the RNAP catalytic core and with free principal sigma factors. http://togogenome.org/gene/1969:CP983_RS34185 ^@ http://purl.uniprot.org/uniprot/A0A7H8THW6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/1969:CP983_RS17295 ^@ http://purl.uniprot.org/uniprot/A0A7H8TBS1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1969:CP983_RS21555 ^@ http://purl.uniprot.org/uniprot/A0A7H8T9S5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/1969:CP983_RS23250 ^@ http://purl.uniprot.org/uniprot/A0A7H8TAM5 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/1969:CP983_RS28550 ^@ http://purl.uniprot.org/uniprot/A0A7H8TDW3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/1969:CP983_RS31775 ^@ http://purl.uniprot.org/uniprot/A0A7H8TF88 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterioferritin family.|||Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/1969:CP983_RS05500 ^@ http://purl.uniprot.org/uniprot/A0A7H8T0R5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1969:CP983_RS31975 ^@ http://purl.uniprot.org/uniprot/A0A7H8TFC5 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/1969:CP983_RS27380 ^@ http://purl.uniprot.org/uniprot/A0A8E3TNJ6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1969:CP983_RS17285 ^@ http://purl.uniprot.org/uniprot/A0A7H8T8U1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1969:CP983_RS12580 ^@ http://purl.uniprot.org/uniprot/A0A7H8T631 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/1969:CP983_RS16115 ^@ http://purl.uniprot.org/uniprot/A0A7H8T723 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family.|||Homotrimer.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine. http://togogenome.org/gene/1969:CP983_RS18055 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7S2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1969:CP983_RS18135 ^@ http://purl.uniprot.org/uniprot/A0A8E3Q6M4 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnA subfamily.|||Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/1969:CP983_RS13945 ^@ http://purl.uniprot.org/uniprot/A0A7H8T5G1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1969:CP983_RS34010 ^@ http://purl.uniprot.org/uniprot/A0A7H8THR6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AlaDH/PNT family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reductive amination of pyruvate to L-alanine. http://togogenome.org/gene/1969:CP983_RS30130 ^@ http://purl.uniprot.org/uniprot/A0A7H8TEB8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1969:CP983_RS17825 ^@ http://purl.uniprot.org/uniprot/A0A7H8T904 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1969:CP983_RS21445 ^@ http://purl.uniprot.org/uniprot/A0A7H8T9Q6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrgA family.|||Cell membrane|||Involved in cell division. http://togogenome.org/gene/1969:CP983_RS12500 ^@ http://purl.uniprot.org/uniprot/A0A7H8T4M1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1969:CP983_RS22835 ^@ http://purl.uniprot.org/uniprot/A0A7H8TBX5 ^@ Similarity ^@ Belongs to the PhoU family.|||Belongs to the UPF0111 family. http://togogenome.org/gene/1969:CP983_RS04770 ^@ http://purl.uniprot.org/uniprot/A0A7H8T1S6 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1969:CP983_RS18140 ^@ http://purl.uniprot.org/uniprot/A0A7H8T976 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1969:CP983_RS21795 ^@ http://purl.uniprot.org/uniprot/A0A7H8TB43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SsgA family.|||Cell septum http://togogenome.org/gene/1969:CP983_RS17270 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7C3 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1969:CP983_RS17340 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7G6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1969:CP983_RS17385 ^@ http://purl.uniprot.org/uniprot/A0A7H8T8W2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1969:CP983_RS17120 ^@ http://purl.uniprot.org/uniprot/A0A8E3PJ16 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/1969:CP983_RS35640 ^@ http://purl.uniprot.org/uniprot/A0A7H8THB1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/1969:CP983_RS37800 ^@ http://purl.uniprot.org/uniprot/A0A7H8TJ19 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1969:CP983_RS28525 ^@ http://purl.uniprot.org/uniprot/A0A7H8TEY5 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1969:CP983_RS33775 ^@ http://purl.uniprot.org/uniprot/A0A7H8TGA2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/1969:CP983_RS17420 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7G2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1969:CP983_RS17070 ^@ http://purl.uniprot.org/uniprot/A0A7H8TBM9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1969:CP983_RS12460 ^@ http://purl.uniprot.org/uniprot/A0A7H8T4H7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1969:CP983_RS34885 ^@ http://purl.uniprot.org/uniprot/A0A7H8THH2 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.|||Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.|||The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group. http://togogenome.org/gene/1969:CP983_RS35120 ^@ http://purl.uniprot.org/uniprot/A0A7H8TIB6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1969:CP983_RS20180 ^@ http://purl.uniprot.org/uniprot/A0A7H8T8R2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/1969:CP983_RS19065 ^@ http://purl.uniprot.org/uniprot/A0A7H8T9N5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/1969:CP983_RS18050 ^@ http://purl.uniprot.org/uniprot/A0A7H8TC45 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1969:CP983_RS18615 ^@ http://purl.uniprot.org/uniprot/A0A7H8T9E0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/1969:CP983_RS17290 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7F5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/1969:CP983_RS25205 ^@ http://purl.uniprot.org/uniprot/A0A7H8TCX5 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/1969:CP983_RS34865 ^@ http://purl.uniprot.org/uniprot/A0A7H8TGU8 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.|||The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/1969:CP983_RS17330 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7G4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1969:CP983_RS28705 ^@ http://purl.uniprot.org/uniprot/A0A7H8THX7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/1969:CP983_RS23080 ^@ http://purl.uniprot.org/uniprot/A0A7H8TC16 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1969:CP983_RS11540 ^@ http://purl.uniprot.org/uniprot/A0A7H8T3X6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/1969:CP983_RS13755 ^@ http://purl.uniprot.org/uniprot/A0A7H8T5F7 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/1969:CP983_RS06325 ^@ http://purl.uniprot.org/uniprot/A0A7H8T134 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1969:CP983_RS30430 ^@ http://purl.uniprot.org/uniprot/A0A7H8TFU4 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1969:CP983_RS17785 ^@ http://purl.uniprot.org/uniprot/A0A8E3TJI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1969:CP983_RS15380 ^@ http://purl.uniprot.org/uniprot/A0A7H8T6J7 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/1969:CP983_RS31800 ^@ http://purl.uniprot.org/uniprot/A0A8E3QAT0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/1969:CP983_RS15795 ^@ http://purl.uniprot.org/uniprot/A0A8E3QB00 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/1969:CP983_RS26295 ^@ http://purl.uniprot.org/uniprot/A0A8E3TKU6 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/1969:CP983_RS38470 ^@ http://purl.uniprot.org/uniprot/A0A7H8TLV8 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/1969:CP983_RS34835 ^@ http://purl.uniprot.org/uniprot/A0A7H8TL02 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1969:CP983_RS15275 ^@ http://purl.uniprot.org/uniprot/A0A8E3Q5N6 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1969:CP983_RS37230 ^@ http://purl.uniprot.org/uniprot/A0A7H8TIW6 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1969:CP983_RS28515 ^@ http://purl.uniprot.org/uniprot/A0A7H8TS85 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1969:CP983_RS04855 ^@ http://purl.uniprot.org/uniprot/A0A7H8T0V7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1969:CP983_RS12150 ^@ http://purl.uniprot.org/uniprot/A0A7H8T8P2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/1969:CP983_RS11465 ^@ http://purl.uniprot.org/uniprot/A0A7H8T3W6 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1969:CP983_RS17595 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7J8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1969:CP983_RS26545 ^@ http://purl.uniprot.org/uniprot/A0A7H8TCD4 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/1969:CP983_RS28275 ^@ http://purl.uniprot.org/uniprot/A0A8E3Q7A3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1969:CP983_RS05205 ^@ http://purl.uniprot.org/uniprot/A0A8E3Q0C9 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1969:CP983_RS34855 ^@ http://purl.uniprot.org/uniprot/A0A7H8TI72 ^@ Caution|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic ubiquitin-like protein family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.|||Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.|||The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome. http://togogenome.org/gene/1969:CP983_RS13095 ^@ http://purl.uniprot.org/uniprot/A0A7H8T661 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1969:CP983_RS34895 ^@ http://purl.uniprot.org/uniprot/A0A7H8TGW2 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1969:CP983_RS02545 ^@ http://purl.uniprot.org/uniprot/A0A8E3TJ72 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1969:CP983_RS17380 ^@ http://purl.uniprot.org/uniprot/A0A7H8T7Q0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1969:CP983_RS16350 ^@ http://purl.uniprot.org/uniprot/A0A7H8TBA7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1969:CP983_RS19295 ^@ http://purl.uniprot.org/uniprot/A0A7H8T9U4 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1969:CP983_RS17045 ^@ http://purl.uniprot.org/uniprot/A0A7H8T778 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1969:CP983_RS14770 ^@ http://purl.uniprot.org/uniprot/A0A7H8T600 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||Nucleus|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1969:CP983_RS21245 ^@ http://purl.uniprot.org/uniprot/A0A7H8T9A7 ^@ Similarity|||Subunit ^@ Belongs to the Bpa family.|||Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings. http://togogenome.org/gene/1969:CP983_RS37070 ^@ http://purl.uniprot.org/uniprot/A0A7H8TI10 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1969:CP983_RS24040 ^@ http://purl.uniprot.org/uniprot/A0A7H8TFH4 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).