http://togogenome.org/gene/1935379:Leucomu_RS04720 ^@ http://purl.uniprot.org/uniprot/A0A410H8T8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/1935379:Leucomu_RS04165 ^@ http://purl.uniprot.org/uniprot/A0A410H8Q1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1935379:Leucomu_RS06155 ^@ http://purl.uniprot.org/uniprot/A0A410H9C0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS00470 ^@ http://purl.uniprot.org/uniprot/A0A410H6R0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS04140 ^@ http://purl.uniprot.org/uniprot/A0A410H8E0 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1935379:Leucomu_RS08095 ^@ http://purl.uniprot.org/uniprot/A0A410HAD6 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/1935379:Leucomu_RS14915 ^@ http://purl.uniprot.org/uniprot/A0A410HDP5 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/1935379:Leucomu_RS08800 ^@ http://purl.uniprot.org/uniprot/A0A410HAL1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1935379:Leucomu_RS03760 ^@ http://purl.uniprot.org/uniprot/A0A410H871 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS12935 ^@ http://purl.uniprot.org/uniprot/A0A410HCJ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS04385 ^@ http://purl.uniprot.org/uniprot/A0A410H8G3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS06435 ^@ http://purl.uniprot.org/uniprot/A0A410H9I4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1935379:Leucomu_RS06505 ^@ http://purl.uniprot.org/uniprot/A0A410H9L6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/1935379:Leucomu_RS14440 ^@ http://purl.uniprot.org/uniprot/A0A410HDI5 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/1935379:Leucomu_RS11955 ^@ http://purl.uniprot.org/uniprot/A0A410HC26 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the CobB/CobQ family.|||Involved in acetate metabolism.|||The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site. http://togogenome.org/gene/1935379:Leucomu_RS11585 ^@ http://purl.uniprot.org/uniprot/A0A410HC29 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/1935379:Leucomu_RS10555 ^@ http://purl.uniprot.org/uniprot/A0A410HEC6 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/1935379:Leucomu_RS00640 ^@ http://purl.uniprot.org/uniprot/A0A410H6R9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS10510 ^@ http://purl.uniprot.org/uniprot/A0A410HC96 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1935379:Leucomu_RS10530 ^@ http://purl.uniprot.org/uniprot/A0A410HBH1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS07900 ^@ http://purl.uniprot.org/uniprot/A0A410HAE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1935379:Leucomu_RS12805 ^@ http://purl.uniprot.org/uniprot/A0A410HCR3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS06685 ^@ http://purl.uniprot.org/uniprot/A0A410H9L4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS11735 ^@ http://purl.uniprot.org/uniprot/A0A410HC95 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1935379:Leucomu_RS03260 ^@ http://purl.uniprot.org/uniprot/A0A410H7X0 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Catalyzes the reversible hydration of carbon dioxide to form bicarbonate. http://togogenome.org/gene/1935379:Leucomu_RS12620 ^@ http://purl.uniprot.org/uniprot/A0A410HCG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS09300 ^@ http://purl.uniprot.org/uniprot/A0A410HB13 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1935379:Leucomu_RS13780 ^@ http://purl.uniprot.org/uniprot/A0A410HD61 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/1935379:Leucomu_RS02185 ^@ http://purl.uniprot.org/uniprot/A0A410H7E1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1935379:Leucomu_RS07925 ^@ http://purl.uniprot.org/uniprot/A0A410HB36 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/1935379:Leucomu_RS13775 ^@ http://purl.uniprot.org/uniprot/A0A410HD55 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS05045 ^@ http://purl.uniprot.org/uniprot/A0A410H8S3 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1935379:Leucomu_RS04715 ^@ http://purl.uniprot.org/uniprot/A0A410H8M0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/1935379:Leucomu_RS13645 ^@ http://purl.uniprot.org/uniprot/A0A410HD29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1935379:Leucomu_RS07285 ^@ http://purl.uniprot.org/uniprot/A0A410H9W7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/1935379:Leucomu_RS05085 ^@ http://purl.uniprot.org/uniprot/A0A410H8T7 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1935379:Leucomu_RS14875 ^@ http://purl.uniprot.org/uniprot/A0A410HDP8 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/1935379:Leucomu_RS06825 ^@ http://purl.uniprot.org/uniprot/A0A410H9P2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1935379:Leucomu_RS06365 ^@ http://purl.uniprot.org/uniprot/A0A410H9H4 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/1935379:Leucomu_RS09185 ^@ http://purl.uniprot.org/uniprot/A0A410HAV2 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/1935379:Leucomu_RS05360 ^@ http://purl.uniprot.org/uniprot/A0A410H8Y1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/1935379:Leucomu_RS14960 ^@ http://purl.uniprot.org/uniprot/A0A410HDQ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/1935379:Leucomu_RS13365 ^@ http://purl.uniprot.org/uniprot/A0A410HCY0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. AI-2 autoinducer porter (TC 3.A.1.2.8) family.|||Cell inner membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/1935379:Leucomu_RS02665 ^@ http://purl.uniprot.org/uniprot/A0A410H7Q2 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/1935379:Leucomu_RS04955 ^@ http://purl.uniprot.org/uniprot/A0A410H8S0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/1935379:Leucomu_RS08785 ^@ http://purl.uniprot.org/uniprot/A0A410HAK5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/1935379:Leucomu_RS05560 ^@ http://purl.uniprot.org/uniprot/A0A410H917 ^@ Cofactor|||Function ^@ Binds 1 [3Fe-4S] cluster.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1935379:Leucomu_RS12215 ^@ http://purl.uniprot.org/uniprot/A0A410HC66 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/1935379:Leucomu_RS09265 ^@ http://purl.uniprot.org/uniprot/A0A410HAW2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1935379:Leucomu_RS06905 ^@ http://purl.uniprot.org/uniprot/A0A410H9Q3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1935379:Leucomu_RS10975 ^@ http://purl.uniprot.org/uniprot/A0A410HBN0 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1935379:Leucomu_RS02300 ^@ http://purl.uniprot.org/uniprot/A0A410H7H7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class II aldolase/RraA-like family.|||Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.|||Homotrimer. http://togogenome.org/gene/1935379:Leucomu_RS08365 ^@ http://purl.uniprot.org/uniprot/A0A410HAH9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rieske iron-sulfur protein family.|||Cell membrane|||Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS08355 ^@ http://purl.uniprot.org/uniprot/A0A410HAD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS08085 ^@ http://purl.uniprot.org/uniprot/A0A410HA88 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/1935379:Leucomu_RS03990 ^@ http://purl.uniprot.org/uniprot/A0A410H899 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1935379:Leucomu_RS00350 ^@ http://purl.uniprot.org/uniprot/A0A410H6P2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1935379:Leucomu_RS09935 ^@ http://purl.uniprot.org/uniprot/A0A410HB58 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS08915 ^@ http://purl.uniprot.org/uniprot/A0A410HAQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/1935379:Leucomu_RS12000 ^@ http://purl.uniprot.org/uniprot/A0A410HC83 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/1935379:Leucomu_RS11065 ^@ http://purl.uniprot.org/uniprot/A0A410HBS0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1935379:Leucomu_RS06720 ^@ http://purl.uniprot.org/uniprot/A0A410H9L8 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/1935379:Leucomu_RS08305 ^@ http://purl.uniprot.org/uniprot/A0A410HAL7 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1935379:Leucomu_RS01015 ^@ http://purl.uniprot.org/uniprot/A0A410H7R1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1935379:Leucomu_RS07715 ^@ http://purl.uniprot.org/uniprot/A0A410HB10 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/1935379:Leucomu_RS04205 ^@ http://purl.uniprot.org/uniprot/A0A410H8E9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1935379:Leucomu_RS04055 ^@ http://purl.uniprot.org/uniprot/A0A410H8C0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/1935379:Leucomu_RS04660 ^@ http://purl.uniprot.org/uniprot/A0A410H8L1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/1935379:Leucomu_RS07355 ^@ http://purl.uniprot.org/uniprot/A0A410H9V7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/1935379:Leucomu_RS11800 ^@ http://purl.uniprot.org/uniprot/A0A410HC60 ^@ Function|||Similarity ^@ Belongs to the HMBS family.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. http://togogenome.org/gene/1935379:Leucomu_RS11470 ^@ http://purl.uniprot.org/uniprot/A0A410HBZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS04020 ^@ http://purl.uniprot.org/uniprot/A0A410H898 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1935379:Leucomu_RS09025 ^@ http://purl.uniprot.org/uniprot/A0A410HAS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DivIVA family.|||Cytoplasm http://togogenome.org/gene/1935379:Leucomu_RS07570 ^@ http://purl.uniprot.org/uniprot/A0A410HA05 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/1935379:Leucomu_RS08685 ^@ http://purl.uniprot.org/uniprot/A0A410HAJ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS00410 ^@ http://purl.uniprot.org/uniprot/A0A410H6R1 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1935379:Leucomu_RS14800 ^@ http://purl.uniprot.org/uniprot/A0A410HDM8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Gfo/Idh/MocA family.|||Homotetramer.|||Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose). http://togogenome.org/gene/1935379:Leucomu_RS05090 ^@ http://purl.uniprot.org/uniprot/A0A410H938 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1935379:Leucomu_RS14525 ^@ http://purl.uniprot.org/uniprot/A0A410HDH7 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1935379:Leucomu_RS09500 ^@ http://purl.uniprot.org/uniprot/A0A410HB02 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1935379:Leucomu_RS09340 ^@ http://purl.uniprot.org/uniprot/A0A410HAV7 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/1935379:Leucomu_RS07685 ^@ http://purl.uniprot.org/uniprot/A0A410HA20 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS08820 ^@ http://purl.uniprot.org/uniprot/A0A410HAL4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/1935379:Leucomu_RS13950 ^@ http://purl.uniprot.org/uniprot/A0A410HD88 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1935379:Leucomu_RS04430 ^@ http://purl.uniprot.org/uniprot/A0A410H8N5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/1935379:Leucomu_RS00230 ^@ http://purl.uniprot.org/uniprot/A0A410H6M1 ^@ Similarity|||Subunit ^@ Belongs to the muconolactone Delta-isomerase family.|||Homodecamer. http://togogenome.org/gene/1935379:Leucomu_RS10535 ^@ http://purl.uniprot.org/uniprot/A0A410HBF3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS15040 ^@ http://purl.uniprot.org/uniprot/A0A410HDU0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/1935379:Leucomu_RS02000 ^@ http://purl.uniprot.org/uniprot/A0A410H7F0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1935379:Leucomu_RS03370 ^@ http://purl.uniprot.org/uniprot/A0A410H809 ^@ Similarity ^@ Belongs to the YjdM family. http://togogenome.org/gene/1935379:Leucomu_RS07670 ^@ http://purl.uniprot.org/uniprot/A0A410HA27 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1935379:Leucomu_RS04790 ^@ http://purl.uniprot.org/uniprot/A0A410H9K8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS02555 ^@ http://purl.uniprot.org/uniprot/A0A410H8J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1935379:Leucomu_RS08775 ^@ http://purl.uniprot.org/uniprot/A0A410HEA0 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/1935379:Leucomu_RS09895 ^@ http://purl.uniprot.org/uniprot/A0A410HC06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1935379:Leucomu_RS12205 ^@ http://purl.uniprot.org/uniprot/A0A410HCC9 ^@ Similarity ^@ Belongs to the CsoR family. http://togogenome.org/gene/1935379:Leucomu_RS14890 ^@ http://purl.uniprot.org/uniprot/A0A410HDR3 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1935379:Leucomu_RS02640 ^@ http://purl.uniprot.org/uniprot/A0A410H7P7 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/1935379:Leucomu_RS14955 ^@ http://purl.uniprot.org/uniprot/A0A410HDN9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/1935379:Leucomu_RS13955 ^@ http://purl.uniprot.org/uniprot/A0A410HD85 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS04015 ^@ http://purl.uniprot.org/uniprot/A0A410H8E2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1935379:Leucomu_RS12200 ^@ http://purl.uniprot.org/uniprot/A0A410HC92 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EamA transporter family.|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS06665 ^@ http://purl.uniprot.org/uniprot/A0A410H9L0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS10245 ^@ http://purl.uniprot.org/uniprot/A0A410HBJ2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1935379:Leucomu_RS04130 ^@ http://purl.uniprot.org/uniprot/A0A410H8I3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1935379:Leucomu_RS12320 ^@ http://purl.uniprot.org/uniprot/A0A410HCB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS12310 ^@ http://purl.uniprot.org/uniprot/A0A410HCI5 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1935379:Leucomu_RS05225 ^@ http://purl.uniprot.org/uniprot/A0A410HE06 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/1935379:Leucomu_RS00495 ^@ http://purl.uniprot.org/uniprot/A0A410H6Z6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NucS endonuclease family.|||Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.|||Cytoplasm http://togogenome.org/gene/1935379:Leucomu_RS12580 ^@ http://purl.uniprot.org/uniprot/A0A410HCC7 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/1935379:Leucomu_RS10870 ^@ http://purl.uniprot.org/uniprot/A0A410HBJ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/1935379:Leucomu_RS06395 ^@ http://purl.uniprot.org/uniprot/A0A410H9L5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DivIVA family.|||Cytoplasm http://togogenome.org/gene/1935379:Leucomu_RS12005 ^@ http://purl.uniprot.org/uniprot/A0A410HC56 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1935379:Leucomu_RS06385 ^@ http://purl.uniprot.org/uniprot/A0A410H9J7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1935379:Leucomu_RS03300 ^@ http://purl.uniprot.org/uniprot/A0A410H7Y3 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/1935379:Leucomu_RS04050 ^@ http://purl.uniprot.org/uniprot/A0A410H8C4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1935379:Leucomu_RS07780 ^@ http://purl.uniprot.org/uniprot/A0A410HE55 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/1935379:Leucomu_RS08795 ^@ http://purl.uniprot.org/uniprot/A0A410HBI8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1935379:Leucomu_RS12740 ^@ http://purl.uniprot.org/uniprot/A0A410HCR2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1935379:Leucomu_RS10515 ^@ http://purl.uniprot.org/uniprot/A0A410HBD6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/1935379:Leucomu_RS05405 ^@ http://purl.uniprot.org/uniprot/A0A410H9U5 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/1935379:Leucomu_RS11115 ^@ http://purl.uniprot.org/uniprot/A0A410HBN7 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1935379:Leucomu_RS07565 ^@ http://purl.uniprot.org/uniprot/A0A410HA31 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1935379:Leucomu_RS10600 ^@ http://purl.uniprot.org/uniprot/A0A410HBQ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/1935379:Leucomu_RS04110 ^@ http://purl.uniprot.org/uniprot/A0A410H8C3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1935379:Leucomu_RS14655 ^@ http://purl.uniprot.org/uniprot/A0A410HDM7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS07230 ^@ http://purl.uniprot.org/uniprot/A0A410H9V8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1935379:Leucomu_RS13730 ^@ http://purl.uniprot.org/uniprot/A0A410HD48 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/1935379:Leucomu_RS00905 ^@ http://purl.uniprot.org/uniprot/A0A410H6V4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1935379:Leucomu_RS14210 ^@ http://purl.uniprot.org/uniprot/A0A410HDD8 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Electron transport system for the ribonucleotide reductase system NrdEF. http://togogenome.org/gene/1935379:Leucomu_RS06380 ^@ http://purl.uniprot.org/uniprot/A0A410H9P8 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1935379:Leucomu_RS05945 ^@ http://purl.uniprot.org/uniprot/A0A410H987 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/1935379:Leucomu_RS11375 ^@ http://purl.uniprot.org/uniprot/A0A410HBW9 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1935379:Leucomu_RS04950 ^@ http://purl.uniprot.org/uniprot/A0A410H8T9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/1935379:Leucomu_RS01595 ^@ http://purl.uniprot.org/uniprot/A0A410H782 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/1935379:Leucomu_RS05430 ^@ http://purl.uniprot.org/uniprot/A0A410H900 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1935379:Leucomu_RS10265 ^@ http://purl.uniprot.org/uniprot/A0A410HBF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS04075 ^@ http://purl.uniprot.org/uniprot/A0A410H8A8 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1935379:Leucomu_RS14920 ^@ http://purl.uniprot.org/uniprot/A0A410HDQ2 ^@ Function|||Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.|||Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate. http://togogenome.org/gene/1935379:Leucomu_RS06275 ^@ http://purl.uniprot.org/uniprot/A0A410H9D9 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/1935379:Leucomu_RS14535 ^@ http://purl.uniprot.org/uniprot/A0A410HDI2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1935379:Leucomu_RS08860 ^@ http://purl.uniprot.org/uniprot/A0A410HAN7 ^@ Similarity|||Subunit ^@ Belongs to the pyruvate kinase family.|||Homotetramer. http://togogenome.org/gene/1935379:Leucomu_RS06805 ^@ http://purl.uniprot.org/uniprot/A0A410H9T5 ^@ Cofactor ^@ Can also use Mn(2+) ion. http://togogenome.org/gene/1935379:Leucomu_RS12175 ^@ http://purl.uniprot.org/uniprot/A0A410HC76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1935379:Leucomu_RS04155 ^@ http://purl.uniprot.org/uniprot/A0A410H8D9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1935379:Leucomu_RS07180 ^@ http://purl.uniprot.org/uniprot/A0A410H9T6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/1935379:Leucomu_RS10565 ^@ http://purl.uniprot.org/uniprot/A0A410HBL0 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1935379:Leucomu_RS04170 ^@ http://purl.uniprot.org/uniprot/A0A410H8H5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/1935379:Leucomu_RS15005 ^@ http://purl.uniprot.org/uniprot/A0A410HDQ1 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/1935379:Leucomu_RS04565 ^@ http://purl.uniprot.org/uniprot/A0A410H8K4 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1935379:Leucomu_RS06480 ^@ http://purl.uniprot.org/uniprot/A0A410H9H6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS13685 ^@ http://purl.uniprot.org/uniprot/A0A410HD32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1935379:Leucomu_RS06350 ^@ http://purl.uniprot.org/uniprot/A0A410H9F5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/1935379:Leucomu_RS10890 ^@ http://purl.uniprot.org/uniprot/A0A410HBK1 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1935379:Leucomu_RS06170 ^@ http://purl.uniprot.org/uniprot/A0A410H9C8 ^@ Similarity ^@ Belongs to the UPF0225 family. http://togogenome.org/gene/1935379:Leucomu_RS01725 ^@ http://purl.uniprot.org/uniprot/A0A410H780 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1935379:Leucomu_RS13805 ^@ http://purl.uniprot.org/uniprot/A0A410HD57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1935379:Leucomu_RS01460 ^@ http://purl.uniprot.org/uniprot/A0A410H731 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1935379:Leucomu_RS07375 ^@ http://purl.uniprot.org/uniprot/A0A410H9Y3 ^@ Function|||Similarity ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. http://togogenome.org/gene/1935379:Leucomu_RS06295 ^@ http://purl.uniprot.org/uniprot/A0A410H9F0 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1935379:Leucomu_RS08390 ^@ http://purl.uniprot.org/uniprot/A0A410HAE9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with subunits I, II and III to form cytochrome c oxidase.|||Belongs to the cytochrome c oxidase bacterial subunit CtaF family.|||Cell membrane|||Membrane|||Part of cytochrome c oxidase, its function is unknown. http://togogenome.org/gene/1935379:Leucomu_RS03445 ^@ http://purl.uniprot.org/uniprot/A0A410H8C7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1935379:Leucomu_RS03190 ^@ http://purl.uniprot.org/uniprot/A0A410H7W2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1935379:Leucomu_RS00135 ^@ http://purl.uniprot.org/uniprot/A0A410H6I9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS01675 ^@ http://purl.uniprot.org/uniprot/A0A410H769 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1935379:Leucomu_RS04190 ^@ http://purl.uniprot.org/uniprot/A0A410H8E8 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1935379:Leucomu_RS00610 ^@ http://purl.uniprot.org/uniprot/A0A410H726 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1935379:Leucomu_RS14950 ^@ http://purl.uniprot.org/uniprot/A0A410HDS4 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/1935379:Leucomu_RS10370 ^@ http://purl.uniprot.org/uniprot/A0A410HBD4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1935379:Leucomu_RS12635 ^@ http://purl.uniprot.org/uniprot/A0A410HCR0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/1935379:Leucomu_RS00105 ^@ http://purl.uniprot.org/uniprot/A0A410H786 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrgA family.|||Cell membrane|||Involved in cell division. http://togogenome.org/gene/1935379:Leucomu_RS08035 ^@ http://purl.uniprot.org/uniprot/A0A410HAG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1935379:Leucomu_RS06710 ^@ http://purl.uniprot.org/uniprot/A0A410H9M0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS11810 ^@ http://purl.uniprot.org/uniprot/A0A410HC69 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1935379:Leucomu_RS07190 ^@ http://purl.uniprot.org/uniprot/A0A410HAS7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/1935379:Leucomu_RS04125 ^@ http://purl.uniprot.org/uniprot/A0A410H8B8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1935379:Leucomu_RS10610 ^@ http://purl.uniprot.org/uniprot/A0A410HBL7 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1935379:Leucomu_RS05335 ^@ http://purl.uniprot.org/uniprot/A0A410H8X7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/1935379:Leucomu_RS08790 ^@ http://purl.uniprot.org/uniprot/A0A410HAS2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1935379:Leucomu_RS11920 ^@ http://purl.uniprot.org/uniprot/A0A410HC54 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1935379:Leucomu_RS14580 ^@ http://purl.uniprot.org/uniprot/A0A410HDI9 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1935379:Leucomu_RS00280 ^@ http://purl.uniprot.org/uniprot/A0A410H6P3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS07250 ^@ http://purl.uniprot.org/uniprot/A0A410HE44 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/1935379:Leucomu_RS04120 ^@ http://purl.uniprot.org/uniprot/A0A410H8G5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1935379:Leucomu_RS07980 ^@ http://purl.uniprot.org/uniprot/A0A410HA64 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1935379:Leucomu_RS04235 ^@ http://purl.uniprot.org/uniprot/A0A410HDY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic pantothenate kinase family.|||Cytoplasm http://togogenome.org/gene/1935379:Leucomu_RS06725 ^@ http://purl.uniprot.org/uniprot/A0A410H9L9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/1935379:Leucomu_RS08995 ^@ http://purl.uniprot.org/uniprot/A0A410HAT3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.|||Homodimer. http://togogenome.org/gene/1935379:Leucomu_RS09030 ^@ http://purl.uniprot.org/uniprot/A0A410HAS0 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/1935379:Leucomu_RS04090 ^@ http://purl.uniprot.org/uniprot/A0A410H8D0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1935379:Leucomu_RS09215 ^@ http://purl.uniprot.org/uniprot/A0A410HAT5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS11645 ^@ http://purl.uniprot.org/uniprot/A0A410HCP2 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/1935379:Leucomu_RS04960 ^@ http://purl.uniprot.org/uniprot/A0A410H8R6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1935379:Leucomu_RS07660 ^@ http://purl.uniprot.org/uniprot/A0A410HA92 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1935379:Leucomu_RS04060 ^@ http://purl.uniprot.org/uniprot/A0A410H8B2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1935379:Leucomu_RS08160 ^@ http://purl.uniprot.org/uniprot/A0A410HAG4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/1935379:Leucomu_RS14540 ^@ http://purl.uniprot.org/uniprot/A0A410HDI0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1935379:Leucomu_RS09200 ^@ http://purl.uniprot.org/uniprot/A0A410HAT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS07905 ^@ http://purl.uniprot.org/uniprot/A0A410HAA3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/1935379:Leucomu_RS07630 ^@ http://purl.uniprot.org/uniprot/A0A410HA12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NlpA lipoprotein family.|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS04295 ^@ http://purl.uniprot.org/uniprot/A0A410H8S1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1935379:Leucomu_RS14965 ^@ http://purl.uniprot.org/uniprot/A0A410HDQ3 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1935379:Leucomu_RS05425 ^@ http://purl.uniprot.org/uniprot/A0A410H918 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1935379:Leucomu_RS12385 ^@ http://purl.uniprot.org/uniprot/A0A410HCF6 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/1935379:Leucomu_RS05370 ^@ http://purl.uniprot.org/uniprot/A0A410H8Y9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/1935379:Leucomu_RS04770 ^@ http://purl.uniprot.org/uniprot/A0A410H8Z3 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/1935379:Leucomu_RS07360 ^@ http://purl.uniprot.org/uniprot/A0A410HA46 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/1935379:Leucomu_RS07700 ^@ http://purl.uniprot.org/uniprot/A0A410HA70 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/1935379:Leucomu_RS05135 ^@ http://purl.uniprot.org/uniprot/A0A410H8W9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/1935379:Leucomu_RS05570 ^@ http://purl.uniprot.org/uniprot/A0A410H9B5 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1935379:Leucomu_RS03840 ^@ http://purl.uniprot.org/uniprot/A0A410H8A9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/1935379:Leucomu_RS04010 ^@ http://purl.uniprot.org/uniprot/A0A410H8M2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1935379:Leucomu_RS05330 ^@ http://purl.uniprot.org/uniprot/A0A410H914 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/1935379:Leucomu_RS12585 ^@ http://purl.uniprot.org/uniprot/A0A410HCH0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the acireductone dioxygenase (ARD) family.|||Binds 1 Fe(2+) cation per monomer.|||Binds 1 nickel ion per monomer.|||Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.|||Monomer. http://togogenome.org/gene/1935379:Leucomu_RS02135 ^@ http://purl.uniprot.org/uniprot/A0A410H7K8 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/1935379:Leucomu_RS06370 ^@ http://purl.uniprot.org/uniprot/A0A410H9G0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1935379:Leucomu_RS04885 ^@ http://purl.uniprot.org/uniprot/A0A410H8P7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS08905 ^@ http://purl.uniprot.org/uniprot/A0A410HAN1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/1935379:Leucomu_RS09035 ^@ http://purl.uniprot.org/uniprot/A0A410HAQ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/1935379:Leucomu_RS12250 ^@ http://purl.uniprot.org/uniprot/A0A410HCH7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS00545 ^@ http://purl.uniprot.org/uniprot/A0A410H6P7 ^@ Function|||Similarity ^@ Belongs to the TrhO family.|||Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs. http://togogenome.org/gene/1935379:Leucomu_RS04410 ^@ http://purl.uniprot.org/uniprot/A0A410H8U0 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1935379:Leucomu_RS11610 ^@ http://purl.uniprot.org/uniprot/A0A410HC14 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/1935379:Leucomu_RS08875 ^@ http://purl.uniprot.org/uniprot/A0A410HAM7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1935379:Leucomu_RS07380 ^@ http://purl.uniprot.org/uniprot/A0A410HA01 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/1935379:Leucomu_RS10500 ^@ http://purl.uniprot.org/uniprot/A0A410HBF5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1935379:Leucomu_RS14030 ^@ http://purl.uniprot.org/uniprot/A0A410HD93 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/1935379:Leucomu_RS04435 ^@ http://purl.uniprot.org/uniprot/A0A410H9E9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/1935379:Leucomu_RS12125 ^@ http://purl.uniprot.org/uniprot/A0A410HCB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS03770 ^@ http://purl.uniprot.org/uniprot/A0A410H8I5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the selenophosphate synthase 1 family. Class I subfamily.|||Binds 1 Mg(2+) ion per monomer.|||Homodimer.|||Synthesizes selenophosphate from selenide and ATP. http://togogenome.org/gene/1935379:Leucomu_RS05165 ^@ http://purl.uniprot.org/uniprot/A0A410H8U5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1935379:Leucomu_RS07410 ^@ http://purl.uniprot.org/uniprot/A0A410H9W8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/1935379:Leucomu_RS11775 ^@ http://purl.uniprot.org/uniprot/A0A410HC37 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1935379:Leucomu_RS04210 ^@ http://purl.uniprot.org/uniprot/A0A410H8E1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/1935379:Leucomu_RS10525 ^@ http://purl.uniprot.org/uniprot/A0A410HBH3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS04265 ^@ http://purl.uniprot.org/uniprot/A0A410HE10 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein S18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/1935379:Leucomu_RS10015 ^@ http://purl.uniprot.org/uniprot/A0A410HC27 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS04070 ^@ http://purl.uniprot.org/uniprot/A0A410H8F2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1935379:Leucomu_RS01830 ^@ http://purl.uniprot.org/uniprot/A0A410H7B5 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/1935379:Leucomu_RS07645 ^@ http://purl.uniprot.org/uniprot/A0A410HA60 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/1935379:Leucomu_RS00485 ^@ http://purl.uniprot.org/uniprot/A0A410H6N7 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/1935379:Leucomu_RS04080 ^@ http://purl.uniprot.org/uniprot/A0A410H8H4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1935379:Leucomu_RS10020 ^@ http://purl.uniprot.org/uniprot/A0A410HB63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS04100 ^@ http://purl.uniprot.org/uniprot/A0A410H8D6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1935379:Leucomu_RS11525 ^@ http://purl.uniprot.org/uniprot/A0A410HCN9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/1935379:Leucomu_RS04025 ^@ http://purl.uniprot.org/uniprot/A0A410H8G2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1935379:Leucomu_RS01440 ^@ http://purl.uniprot.org/uniprot/A0A410H787 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/1935379:Leucomu_RS04145 ^@ http://purl.uniprot.org/uniprot/A0A410H8C6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1935379:Leucomu_RS04785 ^@ http://purl.uniprot.org/uniprot/A0A410H8V0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1935379:Leucomu_RS03235 ^@ http://purl.uniprot.org/uniprot/A0A410H7Y7 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/1935379:Leucomu_RS10270 ^@ http://purl.uniprot.org/uniprot/A0A410HC62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS13310 ^@ http://purl.uniprot.org/uniprot/A0A410HCX1 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1935379:Leucomu_RS02570 ^@ http://purl.uniprot.org/uniprot/A0A410H7N5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS08400 ^@ http://purl.uniprot.org/uniprot/A0A410HAE0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Membrane|||Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). http://togogenome.org/gene/1935379:Leucomu_RS06830 ^@ http://purl.uniprot.org/uniprot/A0A410HE09 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1935379:Leucomu_RS07625 ^@ http://purl.uniprot.org/uniprot/A0A410HA41 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1935379:Leucomu_RS07580 ^@ http://purl.uniprot.org/uniprot/A0A410HA98 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/1935379:Leucomu_RS13975 ^@ http://purl.uniprot.org/uniprot/A0A410HD99 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS04650 ^@ http://purl.uniprot.org/uniprot/A0A410H8Q9 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1935379:Leucomu_RS04175 ^@ http://purl.uniprot.org/uniprot/A0A410H8C8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1935379:Leucomu_RS11790 ^@ http://purl.uniprot.org/uniprot/A0A410HC11 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/1935379:Leucomu_RS09115 ^@ http://purl.uniprot.org/uniprot/A0A410HAY3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/1935379:Leucomu_RS07735 ^@ http://purl.uniprot.org/uniprot/A0A410HA29 ^@ Similarity ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. http://togogenome.org/gene/1935379:Leucomu_RS07990 ^@ http://purl.uniprot.org/uniprot/A0A410HB43 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1935379:Leucomu_RS03270 ^@ http://purl.uniprot.org/uniprot/A0A410H7Z8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1935379:Leucomu_RS08965 ^@ http://purl.uniprot.org/uniprot/A0A410HAP2 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/1935379:Leucomu_RS07775 ^@ http://purl.uniprot.org/uniprot/A0A410HB19 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/1935379:Leucomu_RS11815 ^@ http://purl.uniprot.org/uniprot/A0A410HCP7 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/1935379:Leucomu_RS09385 ^@ http://purl.uniprot.org/uniprot/A0A410HAX8 ^@ Similarity ^@ Belongs to the calycin superfamily. Lipocalin family. http://togogenome.org/gene/1935379:Leucomu_RS04830 ^@ http://purl.uniprot.org/uniprot/A0A410H8P6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS09900 ^@ http://purl.uniprot.org/uniprot/A0A410HB42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1935379:Leucomu_RS08865 ^@ http://purl.uniprot.org/uniprot/A0A410HAP4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/1935379:Leucomu_RS04095 ^@ http://purl.uniprot.org/uniprot/A0A410H8B5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1935379:Leucomu_RS01730 ^@ http://purl.uniprot.org/uniprot/A0A410H7B8 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1935379:Leucomu_RS10305 ^@ http://purl.uniprot.org/uniprot/A0A410HBG8 ^@ Similarity ^@ Belongs to the extradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/1935379:Leucomu_RS06030 ^@ http://purl.uniprot.org/uniprot/A0A410HA66 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1935379:Leucomu_RS04065 ^@ http://purl.uniprot.org/uniprot/A0A410H8N4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/1935379:Leucomu_RS01310 ^@ http://purl.uniprot.org/uniprot/A0A410H719 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS02020 ^@ http://purl.uniprot.org/uniprot/A0A410H7E4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Binds 1 Fe cation per subunit.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/1935379:Leucomu_RS04105 ^@ http://purl.uniprot.org/uniprot/A0A410H8D1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1935379:Leucomu_RS08460 ^@ http://purl.uniprot.org/uniprot/A0A410HAP3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase-binding protein RbpA family.|||Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.|||Forms a complex with the RNAP catalytic core and with free principal sigma factors.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1935379:Leucomu_RS00500 ^@ http://purl.uniprot.org/uniprot/A0A410H6S8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS10560 ^@ http://purl.uniprot.org/uniprot/A0A410HBG6 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1935379:Leucomu_RS01465 ^@ http://purl.uniprot.org/uniprot/A0A410H772 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1935379:Leucomu_RS08805 ^@ http://purl.uniprot.org/uniprot/A0A410HAM6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/1935379:Leucomu_RS01560 ^@ http://purl.uniprot.org/uniprot/A0A410H750 ^@ Similarity ^@ Belongs to the phosphate/phosphite/phosphonate binding protein family. http://togogenome.org/gene/1935379:Leucomu_RS14300 ^@ http://purl.uniprot.org/uniprot/A0A410HDD7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS05575 ^@ http://purl.uniprot.org/uniprot/A0A410H960 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.|||Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.|||Cytoplasm|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1935379:Leucomu_RS04610 ^@ http://purl.uniprot.org/uniprot/A0A410H8K2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS05305 ^@ http://purl.uniprot.org/uniprot/A0A410H8Z7 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/1935379:Leucomu_RS08140 ^@ http://purl.uniprot.org/uniprot/A0A410HA97 ^@ Function|||Similarity ^@ Belongs to the RapZ-like family.|||Displays ATPase and GTPase activities. http://togogenome.org/gene/1935379:Leucomu_RS07255 ^@ http://purl.uniprot.org/uniprot/A0A410HA25 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1935379:Leucomu_RS06300 ^@ http://purl.uniprot.org/uniprot/A0A410H9F1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS06330 ^@ http://purl.uniprot.org/uniprot/A0A410H9K4 ^@ Function|||Similarity ^@ Belongs to the DNA polymerase type-Y family.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/1935379:Leucomu_RS04900 ^@ http://purl.uniprot.org/uniprot/A0A410H8Q6 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1935379:Leucomu_RS05380 ^@ http://purl.uniprot.org/uniprot/A0A410H986 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1935379:Leucomu_RS13725 ^@ http://purl.uniprot.org/uniprot/A0A410HD49 ^@ Cofactor|||Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/1935379:Leucomu_RS00010 ^@ http://purl.uniprot.org/uniprot/A0A410H6I0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/1935379:Leucomu_RS13680 ^@ http://purl.uniprot.org/uniprot/A0A410HD40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1935379:Leucomu_RS11025 ^@ http://purl.uniprot.org/uniprot/A0A410HBP0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1935379:Leucomu_RS05980 ^@ http://purl.uniprot.org/uniprot/A0A410HA56 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1935379:Leucomu_RS02515 ^@ http://purl.uniprot.org/uniprot/A0A410H7M6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS06085 ^@ http://purl.uniprot.org/uniprot/A0A410H9G3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS04890 ^@ http://purl.uniprot.org/uniprot/A0A410H8S6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1935379:Leucomu_RS01930 ^@ http://purl.uniprot.org/uniprot/A0A410H7H8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1935379:Leucomu_RS13810 ^@ http://purl.uniprot.org/uniprot/A0A410HD58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1935379:Leucomu_RS09470 ^@ http://purl.uniprot.org/uniprot/A0A410HB64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gmhB family.|||Cytoplasm http://togogenome.org/gene/1935379:Leucomu_RS08765 ^@ http://purl.uniprot.org/uniprot/A0A410HAK4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/1935379:Leucomu_RS11455 ^@ http://purl.uniprot.org/uniprot/A0A410HCN6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cell surface|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.|||capsule|||cell wall http://togogenome.org/gene/1935379:Leucomu_RS11890 ^@ http://purl.uniprot.org/uniprot/A0A410HCP8 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1935379:Leucomu_RS07680 ^@ http://purl.uniprot.org/uniprot/A0A410HA52 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1935379:Leucomu_RS14490 ^@ http://purl.uniprot.org/uniprot/A0A410HDI6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/1935379:Leucomu_RS06690 ^@ http://purl.uniprot.org/uniprot/A0A410H9R3 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/1935379:Leucomu_RS14370 ^@ http://purl.uniprot.org/uniprot/A0A410HDF2 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/1935379:Leucomu_RS14970 ^@ http://purl.uniprot.org/uniprot/A0A410HDR2 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/1935379:Leucomu_RS11380 ^@ http://purl.uniprot.org/uniprot/A0A410HBT2 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/1935379:Leucomu_RS09960 ^@ http://purl.uniprot.org/uniprot/A0A410HB52 ^@ Similarity ^@ Belongs to the PheA/TfdB FAD monooxygenase family. http://togogenome.org/gene/1935379:Leucomu_RS10580 ^@ http://purl.uniprot.org/uniprot/A0A410HBI3 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/1935379:Leucomu_RS04215 ^@ http://purl.uniprot.org/uniprot/A0A410H8R1 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.