http://togogenome.org/gene/1839801:Dform_RS03755 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6J8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1839801:Dform_RS06375 ^@ http://purl.uniprot.org/uniprot/A0A1P8F806 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/1839801:Dform_RS05390 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7F0 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/1839801:Dform_RS01005 ^@ http://purl.uniprot.org/uniprot/A0A1P8F500 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/1839801:Dform_RS00975 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4Z9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1839801:Dform_RS01045 ^@ http://purl.uniprot.org/uniprot/A0A1P8F556 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1839801:Dform_RS04200 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6Y0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS01095 ^@ http://purl.uniprot.org/uniprot/A0A1P8F566 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS07065 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8G3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/1839801:Dform_RS02180 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5P2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/1839801:Dform_RS01510 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5A8 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1839801:Dform_RS03905 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6N8 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/1839801:Dform_RS07435 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8L6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/1839801:Dform_RS03500 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6E3 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/1839801:Dform_RS05240 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7D5 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1839801:Dform_RS04970 ^@ http://purl.uniprot.org/uniprot/A0A1P8F785 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS02945 ^@ http://purl.uniprot.org/uniprot/A0A1P8F680 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1839801:Dform_RS05985 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7W2 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1839801:Dform_RS07335 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8J6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS10300 ^@ http://purl.uniprot.org/uniprot/A0A1P8FA96 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1839801:Dform_RS04190 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6U1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/1839801:Dform_RS06700 ^@ http://purl.uniprot.org/uniprot/A0A1P8F869 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/1839801:Dform_RS09290 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9S8 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1839801:Dform_RS00490 ^@ http://purl.uniprot.org/uniprot/A0A1P8F535 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/1839801:Dform_RS02655 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6C2 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/1839801:Dform_RS04610 ^@ http://purl.uniprot.org/uniprot/A0A1P8F705 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1839801:Dform_RS10325 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAB6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/1839801:Dform_RS10080 ^@ http://purl.uniprot.org/uniprot/A0A1P8FA85 ^@ Similarity ^@ Belongs to the arsA ATPase family. http://togogenome.org/gene/1839801:Dform_RS09065 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9M6 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/1839801:Dform_RS10275 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAA7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/1839801:Dform_RS03450 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6H7 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1839801:Dform_RS01080 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5F7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1839801:Dform_RS04375 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6W0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1839801:Dform_RS06005 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7T9 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/1839801:Dform_RS03710 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6M3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/1839801:Dform_RS03370 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6Q7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic Ku family.|||Homodimer. Interacts with LigD.|||With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. http://togogenome.org/gene/1839801:Dform_RS03825 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6R0 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/1839801:Dform_RS02170 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5P4 ^@ Function ^@ Involved in the transposition of the insertion sequence. http://togogenome.org/gene/1839801:Dform_RS02965 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6I1 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/1839801:Dform_RS07810 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8U7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS00985 ^@ http://purl.uniprot.org/uniprot/A0A1P8F521 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1839801:Dform_RS06155 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7Z3 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1839801:Dform_RS01070 ^@ http://purl.uniprot.org/uniprot/A0A1P8F571 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1839801:Dform_RS02955 ^@ http://purl.uniprot.org/uniprot/A0A1P8F685 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS05495 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7H2 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/1839801:Dform_RS10485 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAD5 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/1839801:Dform_RS04405 ^@ http://purl.uniprot.org/uniprot/A0A1P8F715 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/1839801:Dform_RS00625 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4T9 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/1839801:Dform_RS03750 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6J9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1839801:Dform_RS01015 ^@ http://purl.uniprot.org/uniprot/A0A1P8F515 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1839801:Dform_RS07315 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8Q5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS05480 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7H9 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/1839801:Dform_RS09250 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9S1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS04585 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7B5 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1839801:Dform_RS00420 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4P7 ^@ Cofactor ^@ Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/1839801:Dform_RS02080 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5M4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/1839801:Dform_RS03120 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6L2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/1839801:Dform_RS00335 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4Z8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/1839801:Dform_RS04780 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7G1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/1839801:Dform_RS02760 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6E2 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/1839801:Dform_RS05270 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7I2 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/1839801:Dform_RS05715 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7P9 ^@ Similarity ^@ In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/1839801:Dform_RS10940 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1839801:Dform_RS05430 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7G9 ^@ Cofactor ^@ Binds 1 copper ion per subunit, denoted as copper B.|||Binds 2 heme groups per subunit, denoted as high- and low-spin. http://togogenome.org/gene/1839801:Dform_RS04330 ^@ http://purl.uniprot.org/uniprot/A0A1P8F784 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endonuclease V family.|||Cytoplasm|||DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. http://togogenome.org/gene/1839801:Dform_RS05745 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7M4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS08250 ^@ http://purl.uniprot.org/uniprot/A0A1P8F962 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS01840 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5I6 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/1839801:Dform_RS03510 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6F2 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/1839801:Dform_RS06670 ^@ http://purl.uniprot.org/uniprot/A0A1P8F888 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/1839801:Dform_RS10425 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAD7 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/1839801:Dform_RS02730 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5Z5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/1839801:Dform_RS01085 ^@ http://purl.uniprot.org/uniprot/A0A1P8F542 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1839801:Dform_RS03345 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6B3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/1839801:Dform_RS02140 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5T1 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/1839801:Dform_RS08395 ^@ http://purl.uniprot.org/uniprot/A0A1P8F982 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS09310 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9Q5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/1839801:Dform_RS02135 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5N3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1839801:Dform_RS05380 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7F9 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/1839801:Dform_RS01000 ^@ http://purl.uniprot.org/uniprot/A0A1P8F508 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1839801:Dform_RS03695 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6N5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/1839801:Dform_RS06345 ^@ http://purl.uniprot.org/uniprot/A0A1P8F844 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1839801:Dform_RS02915 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6H2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1839801:Dform_RS03455 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6E1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/1839801:Dform_RS08865 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9G3 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/1839801:Dform_RS00925 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4Z0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1839801:Dform_RS02060 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5L3 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MobA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.|||Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. http://togogenome.org/gene/1839801:Dform_RS01150 ^@ http://purl.uniprot.org/uniprot/A0A1P8F533 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Homohexamer. Dimer of a homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS00885 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5B8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/1839801:Dform_RS06070 ^@ http://purl.uniprot.org/uniprot/A0A1P8F829 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/1839801:Dform_RS01415 ^@ http://purl.uniprot.org/uniprot/A0A1P8F588 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1839801:Dform_RS07150 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8G5 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/1839801:Dform_RS08330 ^@ http://purl.uniprot.org/uniprot/A0A1P8F951 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/1839801:Dform_RS00015 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4H9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS03620 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6H1 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1839801:Dform_RS02795 ^@ http://purl.uniprot.org/uniprot/A0A1P8F609 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/1839801:Dform_RS02305 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5W6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1839801:Dform_RS08025 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8Z5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1839801:Dform_RS04900 ^@ http://purl.uniprot.org/uniprot/A0A1P8F775 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS00065 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4I6 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/1839801:Dform_RS05530 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7J1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1839801:Dform_RS08855 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9G5 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1839801:Dform_RS05310 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7G4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS00855 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4Y0 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1839801:Dform_RS05170 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7B0 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS04955 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7A5 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. http://togogenome.org/gene/1839801:Dform_RS03165 ^@ http://purl.uniprot.org/uniprot/A0A1P8F687 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/1839801:Dform_RS09135 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9L5 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/1839801:Dform_RS00040 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4H7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1839801:Dform_RS05875 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7V7 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1839801:Dform_RS01200 ^@ http://purl.uniprot.org/uniprot/A0A1P8F546 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1839801:Dform_RS04485 ^@ http://purl.uniprot.org/uniprot/A0A1P8F734 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Membrane http://togogenome.org/gene/1839801:Dform_RS01010 ^@ http://purl.uniprot.org/uniprot/A0A1P8F562 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1839801:Dform_RS04815 ^@ http://purl.uniprot.org/uniprot/A0A1P8F772 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1839801:Dform_RS04770 ^@ http://purl.uniprot.org/uniprot/A0A1P8F770 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/1839801:Dform_RS03110 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6B4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS03530 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6H0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS02825 ^@ http://purl.uniprot.org/uniprot/A0A1P8F668 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1839801:Dform_RS10590 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1839801:Dform_RS05805 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7S1 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/1839801:Dform_RS04370 ^@ http://purl.uniprot.org/uniprot/A0A1P8F709 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1839801:Dform_RS10310 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAC0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/1839801:Dform_RS10510 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAF9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1839801:Dform_RS10885 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAM5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS00685 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4U9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS06595 ^@ http://purl.uniprot.org/uniprot/A0A1P8F885 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/1839801:Dform_RS04360 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6Z1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/1839801:Dform_RS10340 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAB2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1839801:Dform_RS00960 ^@ http://purl.uniprot.org/uniprot/A0A1P8F552 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1839801:Dform_RS06015 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7U9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/1839801:Dform_RS01910 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5I1 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1839801:Dform_RS00535 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4S1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1839801:Dform_RS09425 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9S3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/1839801:Dform_RS00110 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4J3 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1839801:Dform_RS03815 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6P5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/1839801:Dform_RS09435 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9V2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Monomer. http://togogenome.org/gene/1839801:Dform_RS05375 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7K4 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/1839801:Dform_RS07095 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8F4 ^@ Caution|||Function|||Similarity ^@ Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.|||Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS07820 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8V5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/1839801:Dform_RS00920 ^@ http://purl.uniprot.org/uniprot/A0A1P8F545 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/1839801:Dform_RS05220 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7H3 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1839801:Dform_RS10670 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1839801:Dform_RS08595 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9A0 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1839801:Dform_RS07720 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8V9 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1839801:Dform_RS10395 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAE9 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS07050 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8L2 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1839801:Dform_RS09365 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9R5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/1839801:Dform_RS03285 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6G0 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/1839801:Dform_RS04470 ^@ http://purl.uniprot.org/uniprot/A0A1P8F756 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/1839801:Dform_RS05810 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7P6 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/1839801:Dform_RS03295 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6A2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS10795 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAK0 ^@ Function ^@ Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP. http://togogenome.org/gene/1839801:Dform_RS03575 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6U7 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/1839801:Dform_RS06050 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7X2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/1839801:Dform_RS00890 ^@ http://purl.uniprot.org/uniprot/A0A1P8F506 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1839801:Dform_RS08030 ^@ http://purl.uniprot.org/uniprot/A0A1P8F909 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1839801:Dform_RS01040 ^@ http://purl.uniprot.org/uniprot/A0A1P8F518 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1839801:Dform_RS01130 ^@ http://purl.uniprot.org/uniprot/A0A1P8F550 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/1839801:Dform_RS10130 ^@ http://purl.uniprot.org/uniprot/A0A1P8FA68 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS06010 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7W1 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/1839801:Dform_RS07825 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8V1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/1839801:Dform_RS10505 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAF8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/1839801:Dform_RS01745 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5J4 ^@ Similarity ^@ Belongs to the 6-phosphogluconate dehydrogenase family. http://togogenome.org/gene/1839801:Dform_RS00105 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4L8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably interacts with PlsX. http://togogenome.org/gene/1839801:Dform_RS06300 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7Z2 ^@ Similarity ^@ Belongs to the MEMO1 family. http://togogenome.org/gene/1839801:Dform_RS10835 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAL6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/1839801:Dform_RS03330 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6B7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/1839801:Dform_RS06245 ^@ http://purl.uniprot.org/uniprot/A0A1P8F859 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 3 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/1839801:Dform_RS02635 ^@ http://purl.uniprot.org/uniprot/A0A1P8F623 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/1839801:Dform_RS03000 ^@ http://purl.uniprot.org/uniprot/A0A1P8F642 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/1839801:Dform_RS06950 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8J2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1839801:Dform_RS01090 ^@ http://purl.uniprot.org/uniprot/A0A1P8F529 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1839801:Dform_RS04660 ^@ http://purl.uniprot.org/uniprot/A0A1P8F745 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/1839801:Dform_RS04760 ^@ http://purl.uniprot.org/uniprot/A0A1P8F765 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1839801:Dform_RS03170 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6M1 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/1839801:Dform_RS00840 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4Z5 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1839801:Dform_RS02920 ^@ http://purl.uniprot.org/uniprot/A0A1P8F647 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1839801:Dform_RS00790 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4Y6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate.|||Cytoplasm http://togogenome.org/gene/1839801:Dform_RS09165 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9M4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS04345 ^@ http://purl.uniprot.org/uniprot/A0A1P8F714 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1839801:Dform_RS06265 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7X9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1839801:Dform_RS04165 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6S5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1839801:Dform_RS08340 ^@ http://purl.uniprot.org/uniprot/A0A1P8F970 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/1839801:Dform_RS10490 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAE3 ^@ Similarity ^@ Belongs to the carbamoyltransferase HypF family. http://togogenome.org/gene/1839801:Dform_RS03245 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6D6 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/1839801:Dform_RS06405 ^@ http://purl.uniprot.org/uniprot/A0A1P8F840 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Membrane http://togogenome.org/gene/1839801:Dform_RS00570 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4X3 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/1839801:Dform_RS08725 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9D4 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1839801:Dform_RS00315 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4Q6 ^@ Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family. http://togogenome.org/gene/1839801:Dform_RS07255 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8K0 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/1839801:Dform_RS03375 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6E0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/1839801:Dform_RS02810 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6F0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/1839801:Dform_RS00340 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4P6 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/1839801:Dform_RS03995 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6S6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/1839801:Dform_RS09200 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9Q9 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/1839801:Dform_RS04750 ^@ http://purl.uniprot.org/uniprot/A0A1P8F735 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/1839801:Dform_RS09480 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9W0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS04480 ^@ http://purl.uniprot.org/uniprot/A0A1P8F705 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1839801:Dform_RS00965 ^@ http://purl.uniprot.org/uniprot/A0A1P8F505 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1839801:Dform_RS05550 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7L8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/1839801:Dform_RS07475 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8M3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1839801:Dform_RS03580 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6I0 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/1839801:Dform_RS10750 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAI2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS07530 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8R1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell inner membrane|||Cell membrane|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/1839801:Dform_RS01055 ^@ http://purl.uniprot.org/uniprot/A0A1P8F510 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1839801:Dform_RS07905 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8Z8 ^@ Function|||Similarity ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. http://togogenome.org/gene/1839801:Dform_RS05245 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7F4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1839801:Dform_RS07075 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8F1 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS05505 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7K8 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/1839801:Dform_RS05100 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7L4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS10820 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAM4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Forms a complex with TatA.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. http://togogenome.org/gene/1839801:Dform_RS06625 ^@ http://purl.uniprot.org/uniprot/A0A1P8F854 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/1839801:Dform_RS05835 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7T3 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1839801:Dform_RS04995 ^@ http://purl.uniprot.org/uniprot/A0A1P8F782 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/1839801:Dform_RS10355 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAC8 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/1839801:Dform_RS00395 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4P0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS03585 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6G4 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/1839801:Dform_RS05535 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7M7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS06060 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7X0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1839801:Dform_RS05910 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7U2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1839801:Dform_RS03105 ^@ http://purl.uniprot.org/uniprot/A0A1P8F672 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS07350 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8J3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS08010 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8Z4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/1839801:Dform_RS04655 ^@ http://purl.uniprot.org/uniprot/A0A1P8F716 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/1839801:Dform_RS00025 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4G1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS04350 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6V0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/1839801:Dform_RS05000 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7A0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/1839801:Dform_RS00130 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4V7 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1839801:Dform_RS03625 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6V7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1839801:Dform_RS06425 ^@ http://purl.uniprot.org/uniprot/A0A1P8F816 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS01035 ^@ http://purl.uniprot.org/uniprot/A0A1P8F531 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1839801:Dform_RS02475 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5U9 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/1839801:Dform_RS05730 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7S2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS01660 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5D6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS01775 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5G8 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1839801:Dform_RS07060 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8E1 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/1839801:Dform_RS10950 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAN2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1839801:Dform_RS10480 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAD4 ^@ Similarity ^@ Belongs to the HypD family. http://togogenome.org/gene/1839801:Dform_RS02930 ^@ http://purl.uniprot.org/uniprot/A0A1P8F691 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/1839801:Dform_RS05315 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7F1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS07115 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8H8 ^@ Similarity ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. http://togogenome.org/gene/1839801:Dform_RS04105 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6R3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1839801:Dform_RS09510 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9U8 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/1839801:Dform_RS09385 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9U1 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/1839801:Dform_RS08755 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9E3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS03760 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6N4 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1839801:Dform_RS04990 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7E0 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/1839801:Dform_RS02970 ^@ http://purl.uniprot.org/uniprot/A0A1P8F658 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/1839801:Dform_RS04895 ^@ http://purl.uniprot.org/uniprot/A0A1P8F759 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/1839801:Dform_RS03630 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6J0 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS03655 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6L8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS05935 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7V2 ^@ Caution|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the FBP aldolase/phosphatase family.|||Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).|||Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.|||Homooctamer; dimer of tetramers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS08015 ^@ http://purl.uniprot.org/uniprot/A0A1P8F913 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/1839801:Dform_RS05955 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7S8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/1839801:Dform_RS07890 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8Z7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS02050 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5L7 ^@ Function|||Similarity ^@ Belongs to the MoaB/Mog family.|||May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/1839801:Dform_RS07705 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8V6 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/1839801:Dform_RS07370 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8P0 ^@ Similarity ^@ Belongs to the flavin oxidoreductase frp family. http://togogenome.org/gene/1839801:Dform_RS07505 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8S1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1839801:Dform_RS10705 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAH3 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/1839801:Dform_RS04795 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7A7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS09380 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9R3 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/1839801:Dform_RS00325 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4S3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/1839801:Dform_RS00160 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4J8 ^@ Function|||Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/1839801:Dform_RS05705 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7P7 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/1839801:Dform_RS05885 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7U5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS05990 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7S7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1839801:Dform_RS07845 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8V2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/1839801:Dform_RS07045 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8E9 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/1839801:Dform_RS03340 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6B8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1839801:Dform_RS03610 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6H3 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/1839801:Dform_RS04355 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6V3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1839801:Dform_RS07400 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8K2 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/1839801:Dform_RS05125 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7B7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1839801:Dform_RS01125 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5G6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/1839801:Dform_RS04755 ^@ http://purl.uniprot.org/uniprot/A0A1P8F742 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1839801:Dform_RS04860 ^@ http://purl.uniprot.org/uniprot/A0A1P8F763 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/1839801:Dform_RS05825 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7U6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/1839801:Dform_RS09935 ^@ http://purl.uniprot.org/uniprot/A0A1P8FA52 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/1839801:Dform_RS07420 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8Q6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS04365 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6W4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/1839801:Dform_RS02775 ^@ http://purl.uniprot.org/uniprot/A0A1P8F659 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrcB (TC 9.B.71) family.|||Cell membrane|||Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane http://togogenome.org/gene/1839801:Dform_RS04115 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6R4 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/1839801:Dform_RS00145 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4L6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS06675 ^@ http://purl.uniprot.org/uniprot/A0A1P8F862 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/1839801:Dform_RS07490 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8N6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/1839801:Dform_RS06615 ^@ http://purl.uniprot.org/uniprot/A0A1P8F848 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1839801:Dform_RS06475 ^@ http://purl.uniprot.org/uniprot/A0A1P8F827 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS03650 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6H5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1839801:Dform_RS00590 ^@ http://purl.uniprot.org/uniprot/A0A1P8F557 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1839801:Dform_RS09195 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9M2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1839801:Dform_RS05095 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7B1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS06395 ^@ http://purl.uniprot.org/uniprot/A0A1P8F853 ^@ Similarity ^@ Belongs to the IMPDH/GMPR family. http://togogenome.org/gene/1839801:Dform_RS00980 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5D8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1839801:Dform_RS10470 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAE4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS10460 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAF1 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1839801:Dform_RS04185 ^@ http://purl.uniprot.org/uniprot/A0A1P8F752 ^@ Function|||Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/1839801:Dform_RS06435 ^@ http://purl.uniprot.org/uniprot/A0A1P8F821 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1839801:Dform_RS00760 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4V3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/1839801:Dform_RS10875 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAM9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase Y family.|||Cell membrane|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/1839801:Dform_RS08850 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9I2 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/1839801:Dform_RS07770 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8W0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS06165 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7V8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/1839801:Dform_RS10100 ^@ http://purl.uniprot.org/uniprot/A0A1P8FA74 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/1839801:Dform_RS03175 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6A1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/1839801:Dform_RS02290 ^@ http://purl.uniprot.org/uniprot/A0A1P8F650 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. http://togogenome.org/gene/1839801:Dform_RS10125 ^@ http://purl.uniprot.org/uniprot/A0A1P8FA78 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1839801:Dform_RS03180 ^@ http://purl.uniprot.org/uniprot/A0A1P8F686 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/1839801:Dform_RS02040 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5Z8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/1839801:Dform_RS04695 ^@ http://purl.uniprot.org/uniprot/A0A1P8F783 ^@ Cofactor|||Similarity ^@ Belongs to the ELP3 family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1839801:Dform_RS03640 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6M7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/1839801:Dform_RS10260 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAA5 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1839801:Dform_RS05130 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7D7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/1839801:Dform_RS01640 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5E9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/1839801:Dform_RS10345 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAE0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS04390 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6W9 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/1839801:Dform_RS07025 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8E2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/1839801:Dform_RS05890 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7Q1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1839801:Dform_RS06465 ^@ http://purl.uniprot.org/uniprot/A0A1P8F841 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell membrane|||Membrane http://togogenome.org/gene/1839801:Dform_RS05905 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7S0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS00175 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4P2 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/1839801:Dform_RS00935 ^@ http://purl.uniprot.org/uniprot/A0A1P8F516 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1839801:Dform_RS08095 ^@ http://purl.uniprot.org/uniprot/A0A1P8F937 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1839801:Dform_RS08335 ^@ http://purl.uniprot.org/uniprot/A0A1P8F957 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/1839801:Dform_RS02780 ^@ http://purl.uniprot.org/uniprot/A0A1P8F605 ^@ Similarity ^@ Belongs to the UPF0166 family. http://togogenome.org/gene/1839801:Dform_RS07175 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8G7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1839801:Dform_RS00905 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4Y9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type-I 3-dehydroquinase family.|||Homodimer.|||Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS07560 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8V4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1839801:Dform_RS03260 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6A5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/1839801:Dform_RS04785 ^@ http://purl.uniprot.org/uniprot/A0A1P8F777 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/1839801:Dform_RS08545 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9B4 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1839801:Dform_RS06500 ^@ http://purl.uniprot.org/uniprot/A0A1P8F830 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1839801:Dform_RS02145 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5N6 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/1839801:Dform_RS00220 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4Q3 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/1839801:Dform_RS00910 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4Y4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS03470 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6S8 ^@ Cofactor|||Similarity ^@ Belongs to the UPF0313 family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1839801:Dform_RS08840 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9F7 ^@ Function|||Similarity ^@ Belongs to the CbiD family.|||Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. http://togogenome.org/gene/1839801:Dform_RS09020 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9J7 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1839801:Dform_RS10245 ^@ http://purl.uniprot.org/uniprot/A0A1P8FA92 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/1839801:Dform_RS06305 ^@ http://purl.uniprot.org/uniprot/A0A1P8F823 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1839801:Dform_RS00140 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4J1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1839801:Dform_RS07515 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8U5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1839801:Dform_RS01050 ^@ http://purl.uniprot.org/uniprot/A0A1P8F513 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1839801:Dform_RS04475 ^@ http://purl.uniprot.org/uniprot/A0A1P8F703 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/1839801:Dform_RS07635 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8R7 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/1839801:Dform_RS06590 ^@ http://purl.uniprot.org/uniprot/A0A1P8F846 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/1839801:Dform_RS04195 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6S9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1839801:Dform_RS06330 ^@ http://purl.uniprot.org/uniprot/A0A1P8F828 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1839801:Dform_RS06680 ^@ http://purl.uniprot.org/uniprot/A0A1P8F881 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/1839801:Dform_RS05055 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7E2 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. http://togogenome.org/gene/1839801:Dform_RS03975 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6N9 ^@ Similarity ^@ Belongs to the transketolase family. http://togogenome.org/gene/1839801:Dform_RS06220 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7Y1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/1839801:Dform_RS04335 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6X4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/1839801:Dform_RS02650 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5Y5 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1839801:Dform_RS08885 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9J9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Part of an ABC transporter complex. Responsible for energy coupling to the transport system. http://togogenome.org/gene/1839801:Dform_RS03810 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6L0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/1839801:Dform_RS06085 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7Y4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1839801:Dform_RS03135 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6C9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS06140 ^@ http://purl.uniprot.org/uniprot/A0A1P8F802 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1839801:Dform_RS04980 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7D4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/1839801:Dform_RS09035 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9J4 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1839801:Dform_RS00545 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4T6 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/1839801:Dform_RS05365 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7G0 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/1839801:Dform_RS00815 ^@ http://purl.uniprot.org/uniprot/A0A1P8F523 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/1839801:Dform_RS04540 ^@ http://purl.uniprot.org/uniprot/A0A1P8F715 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/1839801:Dform_RS03635 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6H4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/1839801:Dform_RS06075 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7Z6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/1839801:Dform_RS05255 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7F6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1839801:Dform_RS09375 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9R4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/1839801:Dform_RS05735 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7N5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1839801:Dform_RS10145 ^@ http://purl.uniprot.org/uniprot/A0A1P8FA95 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1839801:Dform_RS06340 ^@ http://purl.uniprot.org/uniprot/A0A1P8F876 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS03660 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6I3 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/1839801:Dform_RS02150 ^@ http://purl.uniprot.org/uniprot/A0A1P8F616 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS00610 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4S8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/1839801:Dform_RS07520 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8S0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1839801:Dform_RS01995 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5K1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the thymidylate synthase ThyX family.|||Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.|||Homotetramer. http://togogenome.org/gene/1839801:Dform_RS04180 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6S4 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1839801:Dform_RS06695 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8A7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1839801:Dform_RS05740 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7R8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/1839801:Dform_RS10675 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAI8 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1839801:Dform_RS03990 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6N3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1839801:Dform_RS03910 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6M9 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/1839801:Dform_RS03150 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6B6 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/1839801:Dform_RS04825 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7H0 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/1839801:Dform_RS10365 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAB7 ^@ Function|||Similarity ^@ Belongs to the PemK/MazF family.|||Toxic component of a type II toxin-antitoxin (TA) system. http://togogenome.org/gene/1839801:Dform_RS08715 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9F4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/1839801:Dform_RS06065 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7V4 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1839801:Dform_RS06915 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8B3 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1839801:Dform_RS10500 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAE5 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/1839801:Dform_RS03550 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6F5 ^@ Function ^@ Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. http://togogenome.org/gene/1839801:Dform_RS04730 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7F2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/1839801:Dform_RS04380 ^@ http://purl.uniprot.org/uniprot/A0A1P8F797 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/1839801:Dform_RS10915 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAL8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/1839801:Dform_RS07925 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8W9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1839801:Dform_RS01765 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5G3 ^@ Similarity ^@ Belongs to the 6-phosphogluconate dehydrogenase family. http://togogenome.org/gene/1839801:Dform_RS05235 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7B8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS05110 ^@ http://purl.uniprot.org/uniprot/A0A1P8F795 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/1839801:Dform_RS00125 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4J5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1839801:Dform_RS00945 ^@ http://purl.uniprot.org/uniprot/A0A1P8F537 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/1839801:Dform_RS06640 ^@ http://purl.uniprot.org/uniprot/A0A1P8F856 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/1839801:Dform_RS04940 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7D0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/1839801:Dform_RS09090 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9N8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS07465 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8T5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1839801:Dform_RS04910 ^@ http://purl.uniprot.org/uniprot/A0A1P8F776 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/1839801:Dform_RS05230 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7H4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/1839801:Dform_RS06970 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8C1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1839801:Dform_RS10495 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAH2 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/1839801:Dform_RS00950 ^@ http://purl.uniprot.org/uniprot/A0A1P8F501 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1839801:Dform_RS04810 ^@ http://purl.uniprot.org/uniprot/A0A1P8F751 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1839801:Dform_RS04725 ^@ http://purl.uniprot.org/uniprot/A0A1P8F737 ^@ Function|||Similarity ^@ Belongs to the QueH family.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). http://togogenome.org/gene/1839801:Dform_RS06030 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7U3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/1839801:Dform_RS06470 ^@ http://purl.uniprot.org/uniprot/A0A1P8F855 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1839801:Dform_RS06210 ^@ http://purl.uniprot.org/uniprot/A0A1P8F805 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1839801:Dform_RS05140 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7D9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/1839801:Dform_RS03830 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6L1 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/1839801:Dform_RS10860 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAK9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/1839801:Dform_RS04010 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6P2 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1839801:Dform_RS04205 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6S2 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1839801:Dform_RS00730 ^@ http://purl.uniprot.org/uniprot/A0A1P8F503 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS07745 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8U6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/1839801:Dform_RS00995 ^@ http://purl.uniprot.org/uniprot/A0A1P8F548 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1839801:Dform_RS02160 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5N7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/1839801:Dform_RS09745 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9Y9 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1839801:Dform_RS03195 ^@ http://purl.uniprot.org/uniprot/A0A1P8F683 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/1839801:Dform_RS09180 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9Q0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/1839801:Dform_RS08860 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9I0 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/1839801:Dform_RS05195 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7E6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1839801:Dform_RS04830 ^@ http://purl.uniprot.org/uniprot/A0A1P8F791 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1839801:Dform_RS04590 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6X1 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/1839801:Dform_RS01100 ^@ http://purl.uniprot.org/uniprot/A0A1P8F520 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1839801:Dform_RS06235 ^@ http://purl.uniprot.org/uniprot/A0A1P8F807 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/1839801:Dform_RS10450 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAD1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/1839801:Dform_RS00880 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4Y1 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/1839801:Dform_RS09025 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9J1 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1839801:Dform_RS09275 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9P2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS06020 ^@ http://purl.uniprot.org/uniprot/A0A1P8F819 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/1839801:Dform_RS06790 ^@ http://purl.uniprot.org/uniprot/A0A1P8F887 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS07070 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8F0 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/1839801:Dform_RS10535 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAE1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/1839801:Dform_RS04605 ^@ http://purl.uniprot.org/uniprot/A0A1P8F703 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/1839801:Dform_RS09535 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9X3 ^@ Similarity|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.|||Heterodimer of a large and a small subunit. http://togogenome.org/gene/1839801:Dform_RS01935 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5J7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ferredoxin thioredoxin reductase beta subunit family.|||Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.|||Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin. http://togogenome.org/gene/1839801:Dform_RS03735 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6K9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/1839801:Dform_RS06180 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7W5 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/1839801:Dform_RS10405 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAD6 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/1839801:Dform_RS06955 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8G9 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1839801:Dform_RS00765 ^@ http://purl.uniprot.org/uniprot/A0A1P8F511 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS06270 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7Z8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1839801:Dform_RS00370 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4N7 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1839801:Dform_RS08185 ^@ http://purl.uniprot.org/uniprot/A0A1P8F940 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/1839801:Dform_RS01105 ^@ http://purl.uniprot.org/uniprot/A0A1P8F525 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/1839801:Dform_RS03445 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6D3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/1839801:Dform_RS00955 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4Z1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/1839801:Dform_RS06530 ^@ http://purl.uniprot.org/uniprot/A0A1P8F872 ^@ Similarity ^@ Belongs to the iron/manganese superoxide dismutase family. http://togogenome.org/gene/1839801:Dform_RS03465 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6E4 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/1839801:Dform_RS06175 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7Z5 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/1839801:Dform_RS03725 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6J2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1839801:Dform_RS07430 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8P1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/1839801:Dform_RS00240 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4L0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS01120 ^@ http://purl.uniprot.org/uniprot/A0A1P8F528 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1839801:Dform_RS07860 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8W2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 39 family.|||Membrane http://togogenome.org/gene/1839801:Dform_RS05720 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7M8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/1839801:Dform_RS05400 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7I5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/1839801:Dform_RS01115 ^@ http://purl.uniprot.org/uniprot/A0A1P8F580 ^@ Similarity ^@ Belongs to the PGI/PMI family. http://togogenome.org/gene/1839801:Dform_RS04460 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6X1 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/1839801:Dform_RS08825 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9H1 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1839801:Dform_RS08125 ^@ http://purl.uniprot.org/uniprot/A0A1P8F917 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1839801:Dform_RS09300 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9T0 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/1839801:Dform_RS08445 ^@ http://purl.uniprot.org/uniprot/A0A1P8F974 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1839801:Dform_RS08090 ^@ http://purl.uniprot.org/uniprot/A0A1P8F901 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/1839801:Dform_RS07090 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8I6 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS10700 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAH0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1839801:Dform_RS00845 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4X7 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/1839801:Dform_RS10615 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAI6 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/1839801:Dform_RS08210 ^@ http://purl.uniprot.org/uniprot/A0A1P8F969 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS01075 ^@ http://purl.uniprot.org/uniprot/A0A1P8F517 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/1839801:Dform_RS05895 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7S3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/1839801:Dform_RS07815 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8X3 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/1839801:Dform_RS09835 ^@ http://purl.uniprot.org/uniprot/A0A1P8FA34 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Membrane http://togogenome.org/gene/1839801:Dform_RS03140 ^@ http://purl.uniprot.org/uniprot/A0A1P8F674 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1839801:Dform_RS06035 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7X1 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/1839801:Dform_RS06055 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7V0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1839801:Dform_RS07440 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8M7 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1839801:Dform_RS07785 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8V7 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS06575 ^@ http://purl.uniprot.org/uniprot/A0A1P8F874 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS04525 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6W9 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/1839801:Dform_RS00820 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4X6 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/1839801:Dform_RS05040 ^@ http://purl.uniprot.org/uniprot/A0A1P8F793 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/1839801:Dform_RS07850 ^@ http://purl.uniprot.org/uniprot/A0A1P8F908 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS10650 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAG1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS02360 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5S8 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1839801:Dform_RS00090 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4K2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1839801:Dform_RS05785 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7P5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS04340 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6V9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/1839801:Dform_RS02185 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5U0 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/1839801:Dform_RS01895 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5J3 ^@ Similarity ^@ Belongs to the desulfoferrodoxin family. http://togogenome.org/gene/1839801:Dform_RS02950 ^@ http://purl.uniprot.org/uniprot/A0A1P8F641 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/1839801:Dform_RS10935 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAN8 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1839801:Dform_RS04615 ^@ http://purl.uniprot.org/uniprot/A0A1P8F734 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Membrane http://togogenome.org/gene/1839801:Dform_RS10855 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAK5 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1839801:Dform_RS05560 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7M1 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/1839801:Dform_RS07715 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8X6 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/1839801:Dform_RS02855 ^@ http://purl.uniprot.org/uniprot/A0A1P8F631 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-C family. DnaE2 subfamily.|||Cytoplasm http://togogenome.org/gene/1839801:Dform_RS03030 ^@ http://purl.uniprot.org/uniprot/A0A1P8F656 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/1839801:Dform_RS10790 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAK3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SelA family.|||Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.|||Cytoplasm http://togogenome.org/gene/1839801:Dform_RS05185 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7A8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/1839801:Dform_RS08065 ^@ http://purl.uniprot.org/uniprot/A0A1P8F925 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/1839801:Dform_RS04600 ^@ http://purl.uniprot.org/uniprot/A0A1P8F756 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/1839801:Dform_RS02505 ^@ http://purl.uniprot.org/uniprot/A0A1P8F601 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/1839801:Dform_RS00470 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4V2 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/1839801:Dform_RS01060 ^@ http://purl.uniprot.org/uniprot/A0A1P8F569 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1839801:Dform_RS04885 ^@ http://purl.uniprot.org/uniprot/A0A1P8F769 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/1839801:Dform_RS10335 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAA4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1839801:Dform_RS06080 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7V3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1839801:Dform_RS05210 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7D3 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS03565 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6K4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/1839801:Dform_RS05565 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7K5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 57 family. http://togogenome.org/gene/1839801:Dform_RS00940 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4Z6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1839801:Dform_RS02130 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5S7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/1839801:Dform_RS11370 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7C6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1839801:Dform_RS09440 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9S7 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1839801:Dform_RS03505 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6I7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS04905 ^@ http://purl.uniprot.org/uniprot/A0A1P8F796 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/1839801:Dform_RS07005 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8H7 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/1839801:Dform_RS06525 ^@ http://purl.uniprot.org/uniprot/A0A1P8F836 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1839801:Dform_RS07385 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8K5 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/1839801:Dform_RS05290 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7E4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/1839801:Dform_RS09530 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9U6 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/1839801:Dform_RS08830 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9F9 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1839801:Dform_RS08360 ^@ http://purl.uniprot.org/uniprot/A0A1P8F953 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1839801:Dform_RS05405 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7G5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/1839801:Dform_RS08845 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9J0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1839801:Dform_RS01065 ^@ http://purl.uniprot.org/uniprot/A0A1P8F524 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/1839801:Dform_RS01915 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5I0 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1839801:Dform_RS00900 ^@ http://purl.uniprot.org/uniprot/A0A1P8F527 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS10060 ^@ http://purl.uniprot.org/uniprot/A0A1P8FA59 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/1839801:Dform_RS05555 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7J5 ^@ Function|||Similarity ^@ Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/1839801:Dform_RS00390 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4Q7 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/1839801:Dform_RS08175 ^@ http://purl.uniprot.org/uniprot/A0A1P8F922 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/1839801:Dform_RS05300 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7E8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell membrane|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/1839801:Dform_RS04975 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7J7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/1839801:Dform_RS08000 ^@ http://purl.uniprot.org/uniprot/A0A1P8F932 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS08110 ^@ http://purl.uniprot.org/uniprot/A0A1P8F936 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1839801:Dform_RS03615 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6L4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS04765 ^@ http://purl.uniprot.org/uniprot/A0A1P8F747 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/1839801:Dform_RS00750 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4Z3 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1839801:Dform_RS07055 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8I9 ^@ Function|||Similarity ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. http://togogenome.org/gene/1839801:Dform_RS05610 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7N4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1839801:Dform_RS10685 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAI4 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/1839801:Dform_RS03085 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6C0 ^@ Cofactor|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit. http://togogenome.org/gene/1839801:Dform_RS08115 ^@ http://purl.uniprot.org/uniprot/A0A1P8F916 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1839801:Dform_RS09845 ^@ http://purl.uniprot.org/uniprot/A0A1P8FA24 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/1839801:Dform_RS10390 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAC2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1839801:Dform_RS00650 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4V5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/1839801:Dform_RS07675 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8T7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS01020 ^@ http://purl.uniprot.org/uniprot/A0A1P8F563 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1839801:Dform_RS00405 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4P5 ^@ Similarity ^@ Belongs to the RemA family. http://togogenome.org/gene/1839801:Dform_RS06685 ^@ http://purl.uniprot.org/uniprot/A0A1P8F892 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1839801:Dform_RS07645 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8Q9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS10430 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAC3 ^@ Similarity ^@ Belongs to the NadC/ModD family. http://togogenome.org/gene/1839801:Dform_RS03555 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6J6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/1839801:Dform_RS04880 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7B2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. http://togogenome.org/gene/1839801:Dform_RS03645 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6H8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1839801:Dform_RS09505 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9W5 ^@ Similarity|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.|||Heterodimer of a large and a small subunit. http://togogenome.org/gene/1839801:Dform_RS10305 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAB5 ^@ Similarity ^@ Belongs to the SAM hydrolase / SAM-dependent halogenase family. http://togogenome.org/gene/1839801:Dform_RS05250 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7D8 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1839801:Dform_RS06240 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7Y0 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/1839801:Dform_RS00990 ^@ http://purl.uniprot.org/uniprot/A0A1P8F507 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1839801:Dform_RS02665 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5Z4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/1839801:Dform_RS00930 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5C8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1839801:Dform_RS10540 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAF0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS07830 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8X0 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1839801:Dform_RS04740 ^@ http://purl.uniprot.org/uniprot/A0A1P8F743 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1839801:Dform_RS08035 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8Z1 ^@ Similarity ^@ Belongs to the PstS family. http://togogenome.org/gene/1839801:Dform_RS08055 ^@ http://purl.uniprot.org/uniprot/A0A1P8F924 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS03325 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6D0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/1839801:Dform_RS00385 ^@ http://purl.uniprot.org/uniprot/A0A1P8F512 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS00275 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4M4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1839801:Dform_RS03805 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6K8 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/1839801:Dform_RS06135 ^@ http://purl.uniprot.org/uniprot/A0A1P8F838 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1839801:Dform_RS03740 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6J3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1839801:Dform_RS05275 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7D6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/1839801:Dform_RS04745 ^@ http://purl.uniprot.org/uniprot/A0A1P8F799 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1839801:Dform_RS04175 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6X0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/1839801:Dform_RS05455 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7H7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/1839801:Dform_RS03290 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6A6 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1839801:Dform_RS02510 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5V5 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/1839801:Dform_RS09515 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9W1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/1839801:Dform_RS06200 ^@ http://purl.uniprot.org/uniprot/A0A1P8F813 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS04160 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6V6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1839801:Dform_RS04295 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6U5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/1839801:Dform_RS07455 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8R0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS03440 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6D7 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/1839801:Dform_RS08260 ^@ http://purl.uniprot.org/uniprot/A0A1P8F978 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1839801:Dform_RS07680 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8R5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1839801:Dform_RS07920 ^@ http://purl.uniprot.org/uniprot/A0A1P8F8X5 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/1839801:Dform_RS09245 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9N4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1839801:Dform_RS00030 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4T5 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1839801:Dform_RS00825 ^@ http://purl.uniprot.org/uniprot/A0A1P8F526 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1839801:Dform_RS10475 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAE7 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/1839801:Dform_RS03385 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6H9 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1839801:Dform_RS03545 ^@ http://purl.uniprot.org/uniprot/A0A1P8F6F8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.|||This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one. http://togogenome.org/gene/1839801:Dform_RS10140 ^@ http://purl.uniprot.org/uniprot/A0A1P8FA72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/1839801:Dform_RS06510 ^@ http://purl.uniprot.org/uniprot/A0A1P8F835 ^@ Cofactor|||Function|||Subunit ^@ Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.|||Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.|||Heterodimer of the IorA and IorB subunits. http://togogenome.org/gene/1839801:Dform_RS01205 ^@ http://purl.uniprot.org/uniprot/A0A1P8F5A4 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1839801:Dform_RS10845 ^@ http://purl.uniprot.org/uniprot/A0A1P8FAL1 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1839801:Dform_RS08180 ^@ http://purl.uniprot.org/uniprot/A0A1P8F923 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/1839801:Dform_RS00500 ^@ http://purl.uniprot.org/uniprot/A0A1P8F4Q8 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. http://togogenome.org/gene/1839801:Dform_RS05165 ^@ http://purl.uniprot.org/uniprot/A0A1P8F7G3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/1839801:Dform_RS09445 ^@ http://purl.uniprot.org/uniprot/A0A1P8F9V4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family.