http://togogenome.org/gene/1827580:DC008_RS21060 ^@ http://purl.uniprot.org/uniprot/A0A2S1IH30 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD. http://togogenome.org/gene/1827580:DC008_RS17410 ^@ http://purl.uniprot.org/uniprot/A0A2S1IFF0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/1827580:DC008_RS22610 ^@ http://purl.uniprot.org/uniprot/A0A2S1IHW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1827580:DC008_RS12750 ^@ http://purl.uniprot.org/uniprot/A0A2S1ICY6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GroES chaperonin family.|||Heptamer of 7 subunits arranged in a ring.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1827580:DC008_RS25595 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJF5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/1827580:DC008_RS24255 ^@ http://purl.uniprot.org/uniprot/A0A2S1IIQ7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1827580:DC008_RS19745 ^@ http://purl.uniprot.org/uniprot/A0A2S1IQA3 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/1827580:DC008_RS19865 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0060 family.|||Cell membrane http://togogenome.org/gene/1827580:DC008_RS23945 ^@ http://purl.uniprot.org/uniprot/A0A2S1III4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/1827580:DC008_RS13010 ^@ http://purl.uniprot.org/uniprot/A0A2S1ID33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1827580:DC008_RS23980 ^@ http://purl.uniprot.org/uniprot/A0A2S1IIK5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/1827580:DC008_RS11280 ^@ http://purl.uniprot.org/uniprot/A0A2S1IC93 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/1827580:DC008_RS28090 ^@ http://purl.uniprot.org/uniprot/A0A2S1IKN5 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1827580:DC008_RS21180 ^@ http://purl.uniprot.org/uniprot/A0A2S1IH48 ^@ Similarity ^@ Belongs to the IMPDH/GMPR family. http://togogenome.org/gene/1827580:DC008_RS05530 ^@ http://purl.uniprot.org/uniprot/A0A2S1I9K4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1827580:DC008_RS19400 ^@ http://purl.uniprot.org/uniprot/A0A2S1IG56 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/1827580:DC008_RS31640 ^@ http://purl.uniprot.org/uniprot/A0A2S1IME4 ^@ Similarity ^@ Belongs to the CsoR family. http://togogenome.org/gene/1827580:DC008_RS10185 ^@ http://purl.uniprot.org/uniprot/A0A2S1IBP7 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/1827580:DC008_RS26190 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJQ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/1827580:DC008_RS29460 ^@ http://purl.uniprot.org/uniprot/A0A2S1ILD2 ^@ Similarity ^@ Belongs to the DDAH family. http://togogenome.org/gene/1827580:DC008_RS10575 ^@ http://purl.uniprot.org/uniprot/A0A2S1IBX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1827580:DC008_RS25280 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJD7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1827580:DC008_RS11420 ^@ http://purl.uniprot.org/uniprot/A0A2S1ICA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/1827580:DC008_RS20860 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGY4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/1827580:DC008_RS22730 ^@ http://purl.uniprot.org/uniprot/A0A2S1IIF8 ^@ Cofactor|||Function ^@ Binds 1 [3Fe-4S] cluster.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1827580:DC008_RS11305 ^@ http://purl.uniprot.org/uniprot/A0A2S1ICV1 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1827580:DC008_RS05040 ^@ http://purl.uniprot.org/uniprot/A0A2S1I944 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1827580:DC008_RS07830 ^@ http://purl.uniprot.org/uniprot/A0A2S1IAH6 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/1827580:DC008_RS09030 ^@ http://purl.uniprot.org/uniprot/A0A2S1IBC0 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1827580:DC008_RS11395 ^@ http://purl.uniprot.org/uniprot/A0A2S1ICB9 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/1827580:DC008_RS29040 ^@ http://purl.uniprot.org/uniprot/A0A2S1IL52 ^@ Similarity ^@ Belongs to the PTPS family. QueD subfamily. http://togogenome.org/gene/1827580:DC008_RS23940 ^@ http://purl.uniprot.org/uniprot/A0A2S1IIJ1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1827580:DC008_RS08795 ^@ http://purl.uniprot.org/uniprot/A0A2S1IBL8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1827580:DC008_RS18565 ^@ http://purl.uniprot.org/uniprot/A0A2S1IFS0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1827580:DC008_RS27020 ^@ http://purl.uniprot.org/uniprot/A0A2S1IK48 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1827580:DC008_RS15765 ^@ http://purl.uniprot.org/uniprot/A0A2S1IEH4 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/1827580:DC008_RS18730 ^@ http://purl.uniprot.org/uniprot/A0A2S1IFZ9 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/1827580:DC008_RS06470 ^@ http://purl.uniprot.org/uniprot/A0A2S1I9S8 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/1827580:DC008_RS25130 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJ83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/1827580:DC008_RS34635 ^@ http://purl.uniprot.org/uniprot/A0A2S1INU9 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1827580:DC008_RS06030 ^@ http://purl.uniprot.org/uniprot/A0A2S1I9J4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1827580:DC008_RS20755 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGW1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1827580:DC008_RS20015 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGI8 ^@ Similarity ^@ Belongs to the UbiD family. http://togogenome.org/gene/1827580:DC008_RS25655 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJG5 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/1827580:DC008_RS01860 ^@ http://purl.uniprot.org/uniprot/A0A2S1I7D5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1827580:DC008_RS11275 ^@ http://purl.uniprot.org/uniprot/A0A2S1ICF4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/1827580:DC008_RS21105 ^@ http://purl.uniprot.org/uniprot/A0A2S1IH39 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1827580:DC008_RS10205 ^@ http://purl.uniprot.org/uniprot/A0A2S1IBV1 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/1827580:DC008_RS05355 ^@ http://purl.uniprot.org/uniprot/A0A2S1I9B2 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/1827580:DC008_RS06240 ^@ http://purl.uniprot.org/uniprot/A0A2S1I9N6 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.|||Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.|||The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group. http://togogenome.org/gene/1827580:DC008_RS15100 ^@ http://purl.uniprot.org/uniprot/A0A2S1IE52 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DtxR/MntR family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1827580:DC008_RS08965 ^@ http://purl.uniprot.org/uniprot/A0A2S1IBB0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterioferritin family.|||Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/1827580:DC008_RS20705 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGW2 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1827580:DC008_RS11590 ^@ http://purl.uniprot.org/uniprot/A0A2S1ICD5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1827580:DC008_RS06870 ^@ http://purl.uniprot.org/uniprot/A0A2S1IA87 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/1827580:DC008_RS19355 ^@ http://purl.uniprot.org/uniprot/A0A2S1IG75 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/1827580:DC008_RS20735 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGX2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1827580:DC008_RS20195 ^@ http://purl.uniprot.org/uniprot/A0A2S1IH94 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1827580:DC008_RS07560 ^@ http://purl.uniprot.org/uniprot/A0A2S1IAH3 ^@ Function|||Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.|||Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate. http://togogenome.org/gene/1827580:DC008_RS05400 ^@ http://purl.uniprot.org/uniprot/A0A2S1I9D8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1827580:DC008_RS27820 ^@ http://purl.uniprot.org/uniprot/A0A2S1IKU4 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1827580:DC008_RS16480 ^@ http://purl.uniprot.org/uniprot/A0A2S1IF02 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1827580:DC008_RS07175 ^@ http://purl.uniprot.org/uniprot/A0A2S1IAE0 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/1827580:DC008_RS22455 ^@ http://purl.uniprot.org/uniprot/A0A2S1IHT5 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/1827580:DC008_RS17455 ^@ http://purl.uniprot.org/uniprot/A0A2S1IFD7 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/1827580:DC008_RS17940 ^@ http://purl.uniprot.org/uniprot/A0A2S1IFN6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1827580:DC008_RS31760 ^@ http://purl.uniprot.org/uniprot/A0A2S1IMG6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/1827580:DC008_RS04365 ^@ http://purl.uniprot.org/uniprot/A0A2S1IPB6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1827580:DC008_RS11205 ^@ http://purl.uniprot.org/uniprot/A0A2S1IC79 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/1827580:DC008_RS20865 ^@ http://purl.uniprot.org/uniprot/A0A2S1IQ56 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1827580:DC008_RS05635 ^@ http://purl.uniprot.org/uniprot/A0A2S1I9C5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.|||Cell membrane|||Contains a di-nuclear catalytic Mg(2+) center.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1827580:DC008_RS15935 ^@ http://purl.uniprot.org/uniprot/A0A2S1IEQ1 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1827580:DC008_RS05730 ^@ http://purl.uniprot.org/uniprot/A0A2S1I9E8 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1827580:DC008_RS31205 ^@ http://purl.uniprot.org/uniprot/A0A2S1IM78 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1827580:DC008_RS34570 ^@ http://purl.uniprot.org/uniprot/A0A2S1INT9 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/1827580:DC008_RS08005 ^@ http://purl.uniprot.org/uniprot/A0A2S1IAK3 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/1827580:DC008_RS18740 ^@ http://purl.uniprot.org/uniprot/A0A2S1IG23 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine. http://togogenome.org/gene/1827580:DC008_RS20895 ^@ http://purl.uniprot.org/uniprot/A0A2S1IHK6 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1827580:DC008_RS29595 ^@ http://purl.uniprot.org/uniprot/A0A2S1ILG0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IPP isomerase type 1 family.|||Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).|||Cytoplasm http://togogenome.org/gene/1827580:DC008_RS20850 ^@ http://purl.uniprot.org/uniprot/A0A2S1IH24 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1827580:DC008_RS30740 ^@ http://purl.uniprot.org/uniprot/A0A2S1ILY3 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/1827580:DC008_RS19660 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGC8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1827580:DC008_RS20760 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGX4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1827580:DC008_RS05705 ^@ http://purl.uniprot.org/uniprot/A0A2S1I9E1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SsgA family.|||Cell septum http://togogenome.org/gene/1827580:DC008_RS10035 ^@ http://purl.uniprot.org/uniprot/A0A2S1IBS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1827580:DC008_RS21170 ^@ http://purl.uniprot.org/uniprot/A0A2S1IH54 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1827580:DC008_RS06035 ^@ http://purl.uniprot.org/uniprot/A0A2S1IA34 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1827580:DC008_RS33535 ^@ http://purl.uniprot.org/uniprot/A0A2S1INE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1827580:DC008_RS20200 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGP1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1827580:DC008_RS23120 ^@ http://purl.uniprot.org/uniprot/A0A2S1II53 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1827580:DC008_RS25520 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJH4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/1827580:DC008_RS00045 ^@ http://purl.uniprot.org/uniprot/A0A2S1INU9 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1827580:DC008_RS05465 ^@ http://purl.uniprot.org/uniprot/A0A2S1I9D0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/1827580:DC008_RS17660 ^@ http://purl.uniprot.org/uniprot/A0A2S1IFB6 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1827580:DC008_RS10880 ^@ http://purl.uniprot.org/uniprot/A0A2S1IC16 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/1827580:DC008_RS26945 ^@ http://purl.uniprot.org/uniprot/A0A2S1IK19 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1827580:DC008_RS12890 ^@ http://purl.uniprot.org/uniprot/A0A2S1ID93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SsgA family.|||Cell septum http://togogenome.org/gene/1827580:DC008_RS20205 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGR3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1827580:DC008_RS05155 ^@ http://purl.uniprot.org/uniprot/A0A2S1I930 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase-binding protein RbpA family.|||Bind 1 Zn(2+) per subunit.|||Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.|||Forms a complex with the RNAP catalytic core and with free principal sigma factors. http://togogenome.org/gene/1827580:DC008_RS06290 ^@ http://purl.uniprot.org/uniprot/A0A2S1I9P7 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1827580:DC008_RS10725 ^@ http://purl.uniprot.org/uniprot/A0A2S1IC17 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/1827580:DC008_RS05510 ^@ http://purl.uniprot.org/uniprot/A0A2S1IPC8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/1827580:DC008_RS17575 ^@ http://purl.uniprot.org/uniprot/A0A2S1IFH9 ^@ Similarity ^@ Belongs to the 6-phosphogluconate dehydrogenase family. http://togogenome.org/gene/1827580:DC008_RS20825 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGW9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1827580:DC008_RS07680 ^@ http://purl.uniprot.org/uniprot/A0A2S1IAF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1827580:DC008_RS32720 ^@ http://purl.uniprot.org/uniprot/A0A2S1IQL5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1827580:DC008_RS24015 ^@ http://purl.uniprot.org/uniprot/A0A2S1IIL7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1827580:DC008_RS20040 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGL5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnE family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. http://togogenome.org/gene/1827580:DC008_RS22270 ^@ http://purl.uniprot.org/uniprot/A0A2S1IHQ7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1827580:DC008_RS05605 ^@ http://purl.uniprot.org/uniprot/A0A2S1I9B5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1827580:DC008_RS21175 ^@ http://purl.uniprot.org/uniprot/A0A2S1IH28 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/1827580:DC008_RS06715 ^@ http://purl.uniprot.org/uniprot/A0A2S1I9Y1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1827580:DC008_RS07790 ^@ http://purl.uniprot.org/uniprot/A0A2S1IAH9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.|||Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.|||Cytoplasm|||Homotrimer. http://togogenome.org/gene/1827580:DC008_RS20845 ^@ http://purl.uniprot.org/uniprot/A0A2S1IH18 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1827580:DC008_RS28350 ^@ http://purl.uniprot.org/uniprot/A0A2S1IL33 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. http://togogenome.org/gene/1827580:DC008_RS15200 ^@ http://purl.uniprot.org/uniprot/A0A2S1IE63 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1827580:DC008_RS13835 ^@ http://purl.uniprot.org/uniprot/A0A2S1IDJ8 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1827580:DC008_RS11200 ^@ http://purl.uniprot.org/uniprot/A0A2S1ICT2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1827580:DC008_RS01855 ^@ http://purl.uniprot.org/uniprot/A0A2S1I7I0 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1827580:DC008_RS04960 ^@ http://purl.uniprot.org/uniprot/A0A2S1I954 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1827580:DC008_RS13045 ^@ http://purl.uniprot.org/uniprot/A0A2S1ID80 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/1827580:DC008_RS22055 ^@ http://purl.uniprot.org/uniprot/A0A2S1IHM8 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1827580:DC008_RS13345 ^@ http://purl.uniprot.org/uniprot/A0A2S1IDA1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF2.|||Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. http://togogenome.org/gene/1827580:DC008_RS25215 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJ69 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/1827580:DC008_RS09555 ^@ http://purl.uniprot.org/uniprot/A0A2S1IPJ9 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1827580:DC008_RS15795 ^@ http://purl.uniprot.org/uniprot/A0A2S1IEL4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyltransferase group 1 family. MshA subfamily.|||Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.|||Homodimer. http://togogenome.org/gene/1827580:DC008_RS19170 ^@ http://purl.uniprot.org/uniprot/A0A2S1IG12 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1827580:DC008_RS29505 ^@ http://purl.uniprot.org/uniprot/A0A2S1ILG1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1827580:DC008_RS24205 ^@ http://purl.uniprot.org/uniprot/A0A2S1IIP7 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1827580:DC008_RS28705 ^@ http://purl.uniprot.org/uniprot/A0A2S1IL12 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/1827580:DC008_RS15350 ^@ http://purl.uniprot.org/uniprot/A0A2S1IEE5 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/1827580:DC008_RS03130 ^@ http://purl.uniprot.org/uniprot/A0A2S1I8C4 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/1827580:DC008_RS24070 ^@ http://purl.uniprot.org/uniprot/A0A2S1IIM0 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1827580:DC008_RS07925 ^@ http://purl.uniprot.org/uniprot/A0A2S1IAK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1827580:DC008_RS12070 ^@ http://purl.uniprot.org/uniprot/A0A2S1ICL6 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1827580:DC008_RS10970 ^@ http://purl.uniprot.org/uniprot/A0A2S1IPL5 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/1827580:DC008_RS29455 ^@ http://purl.uniprot.org/uniprot/A0A2S1ILB6 ^@ Cofactor|||Similarity ^@ Belongs to the fatty acid desaturase type 2 family.|||Binds 2 iron ions per subunit. http://togogenome.org/gene/1827580:DC008_RS20930 ^@ http://purl.uniprot.org/uniprot/A0A2S1IH04 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1827580:DC008_RS20920 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGZ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1827580:DC008_RS25065 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJ85 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1827580:DC008_RS09130 ^@ http://purl.uniprot.org/uniprot/A0A2S1IB79 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1827580:DC008_RS20630 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGY8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1827580:DC008_RS07270 ^@ http://purl.uniprot.org/uniprot/A0A2S1IA78 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/1827580:DC008_RS05260 ^@ http://purl.uniprot.org/uniprot/A0A2S1I967 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/1827580:DC008_RS20805 ^@ http://purl.uniprot.org/uniprot/A0A2S1IH05 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1827580:DC008_RS04965 ^@ http://purl.uniprot.org/uniprot/A0A2S1I915 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/1827580:DC008_RS22845 ^@ http://purl.uniprot.org/uniprot/A0A2S1II08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/1827580:DC008_RS04360 ^@ http://purl.uniprot.org/uniprot/A0A2S1I8S9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease beta subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1827580:DC008_RS03990 ^@ http://purl.uniprot.org/uniprot/A0A2S1I8G9 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1827580:DC008_RS14460 ^@ http://purl.uniprot.org/uniprot/A0A2S1IE11 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/1827580:DC008_RS15940 ^@ http://purl.uniprot.org/uniprot/A0A2S1IEJ7 ^@ Caution|||Similarity ^@ Belongs to the nitrobindin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Lacks the conserved His residue that binds heme iron in the nitrobindin family. http://togogenome.org/gene/1827580:DC008_RS24485 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJ88 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1827580:DC008_RS05255 ^@ http://purl.uniprot.org/uniprot/A0A2S1I952 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/1827580:DC008_RS14730 ^@ http://purl.uniprot.org/uniprot/A0A2S1IDX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1827580:DC008_RS28790 ^@ http://purl.uniprot.org/uniprot/A0A2S1IL07 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1827580:DC008_RS04800 ^@ http://purl.uniprot.org/uniprot/A0A2S1I8Y7 ^@ Function|||Subcellular Location Annotation ^@ Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.|||Membrane http://togogenome.org/gene/1827580:DC008_RS25840 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJI3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1827580:DC008_RS12850 ^@ http://purl.uniprot.org/uniprot/A0A2S1ID04 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/1827580:DC008_RS17555 ^@ http://purl.uniprot.org/uniprot/A0A2S1IFB0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/1827580:DC008_RS13330 ^@ http://purl.uniprot.org/uniprot/A0A2S1IDD1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/1827580:DC008_RS05815 ^@ http://purl.uniprot.org/uniprot/A0A2S1I9Q2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1827580:DC008_RS20945 ^@ http://purl.uniprot.org/uniprot/A0A2S1IHL5 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1827580:DC008_RS20995 ^@ http://purl.uniprot.org/uniprot/A0A2S1IH00 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1827580:DC008_RS23950 ^@ http://purl.uniprot.org/uniprot/A0A2S1III9 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/1827580:DC008_RS24010 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJ03 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/1827580:DC008_RS02245 ^@ http://purl.uniprot.org/uniprot/A0A2S1I7R3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1827580:DC008_RS21810 ^@ http://purl.uniprot.org/uniprot/A0A2S1IHE2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1827580:DC008_RS20795 ^@ http://purl.uniprot.org/uniprot/A0A2S1IH08 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1827580:DC008_RS20710 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGW7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1827580:DC008_RS20815 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGY3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1827580:DC008_RS10200 ^@ http://purl.uniprot.org/uniprot/A0A2S1IBS5 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1827580:DC008_RS13400 ^@ http://purl.uniprot.org/uniprot/A0A2S1IDI9 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/1827580:DC008_RS33005 ^@ http://purl.uniprot.org/uniprot/A0A2S1IN49 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1827580:DC008_RS19575 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGB9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1827580:DC008_RS07555 ^@ http://purl.uniprot.org/uniprot/A0A2S1IAC9 ^@ Function|||Similarity ^@ Belongs to the acetyltransferase family. EctA subfamily.|||Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A. http://togogenome.org/gene/1827580:DC008_RS19590 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGF2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DisA family.|||Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.|||Homooctamer.|||Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. http://togogenome.org/gene/1827580:DC008_RS10720 ^@ http://purl.uniprot.org/uniprot/A0A2S1IC01 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/1827580:DC008_RS20890 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGZ9 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1827580:DC008_RS13655 ^@ http://purl.uniprot.org/uniprot/A0A2S1IDE5 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1827580:DC008_RS17545 ^@ http://purl.uniprot.org/uniprot/A0A2S1IFB3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/1827580:DC008_RS20145 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGN3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1827580:DC008_RS24550 ^@ http://purl.uniprot.org/uniprot/A0A2S1IIZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1827580:DC008_RS20875 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGZ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1827580:DC008_RS20385 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGR5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/1827580:DC008_RS21375 ^@ http://purl.uniprot.org/uniprot/A0A2S1IH79 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/1827580:DC008_RS18440 ^@ http://purl.uniprot.org/uniprot/A0A2S1IFX8 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1827580:DC008_RS08760 ^@ http://purl.uniprot.org/uniprot/A0A2S1IB69 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/1827580:DC008_RS18430 ^@ http://purl.uniprot.org/uniprot/A0A2S1IFU8 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1827580:DC008_RS25195 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJ63 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/1827580:DC008_RS05410 ^@ http://purl.uniprot.org/uniprot/A0A2S1I9C2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS13 family. http://togogenome.org/gene/1827580:DC008_RS13315 ^@ http://purl.uniprot.org/uniprot/A0A2S1IDX5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1827580:DC008_RS24640 ^@ http://purl.uniprot.org/uniprot/A0A2S1IIV8 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1827580:DC008_RS18270 ^@ http://purl.uniprot.org/uniprot/A0A2S1IFL8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1827580:DC008_RS20855 ^@ http://purl.uniprot.org/uniprot/A0A2S1IH14 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1827580:DC008_RS21000 ^@ http://purl.uniprot.org/uniprot/A0A2S1IH19 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/1827580:DC008_RS04270 ^@ http://purl.uniprot.org/uniprot/A0A2S1I8M3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CobB/CobQ family. GatD subfamily.|||Forms a heterodimer with MurT.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT. http://togogenome.org/gene/1827580:DC008_RS20700 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGV2 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/1827580:DC008_RS23990 ^@ http://purl.uniprot.org/uniprot/A0A2S1IIJ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1827580:DC008_RS09155 ^@ http://purl.uniprot.org/uniprot/A0A2S1IB76 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Membrane|||Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). http://togogenome.org/gene/1827580:DC008_RS20900 ^@ http://purl.uniprot.org/uniprot/A0A2S1IH10 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1827580:DC008_RS34430 ^@ http://purl.uniprot.org/uniprot/A0A2S1INU1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1827580:DC008_RS07235 ^@ http://purl.uniprot.org/uniprot/A0A2S1IA71 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/1827580:DC008_RS14170 ^@ http://purl.uniprot.org/uniprot/A0A2S1IDQ2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/1827580:DC008_RS23525 ^@ http://purl.uniprot.org/uniprot/A0A2S1IIT2 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1827580:DC008_RS16450 ^@ http://purl.uniprot.org/uniprot/A0A2S1IES7 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/1827580:DC008_RS15445 ^@ http://purl.uniprot.org/uniprot/A0A2S1IEB3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1827580:DC008_RS17510 ^@ http://purl.uniprot.org/uniprot/A0A2S1IFE4 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1827580:DC008_RS04950 ^@ http://purl.uniprot.org/uniprot/A0A2S1I8Z4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sbp family.|||Cell membrane http://togogenome.org/gene/1827580:DC008_RS20750 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGZ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1827580:DC008_RS20685 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGZ7 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1827580:DC008_RS02630 ^@ http://purl.uniprot.org/uniprot/A0A2S1I7R0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1827580:DC008_RS02515 ^@ http://purl.uniprot.org/uniprot/A0A2S1I7P7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1827580:DC008_RS24000 ^@ http://purl.uniprot.org/uniprot/A0A2S1IIK1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/1827580:DC008_RS20810 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGX5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/1827580:DC008_RS13040 ^@ http://purl.uniprot.org/uniprot/A0A2S1ID75 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1827580:DC008_RS20250 ^@ http://purl.uniprot.org/uniprot/A0A2S1IHA4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1827580:DC008_RS33560 ^@ http://purl.uniprot.org/uniprot/A0A2S1ING6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1827580:DC008_RS20885 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGX8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1827580:DC008_RS19770 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGH9 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1827580:DC008_RS19375 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/1827580:DC008_RS23290 ^@ http://purl.uniprot.org/uniprot/A0A2S1II73 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1827580:DC008_RS07845 ^@ http://purl.uniprot.org/uniprot/A0A2S1IAI0 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/1827580:DC008_RS16485 ^@ http://purl.uniprot.org/uniprot/A0A2S1IPU5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1827580:DC008_RS05390 ^@ http://purl.uniprot.org/uniprot/A0A2S1I978 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/1827580:DC008_RS19125 ^@ http://purl.uniprot.org/uniprot/A0A2S1IG40 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/1827580:DC008_RS11015 ^@ http://purl.uniprot.org/uniprot/A0A2S1IC51 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1827580:DC008_RS09725 ^@ http://purl.uniprot.org/uniprot/A0A2S1IBH1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1827580:DC008_RS17215 ^@ http://purl.uniprot.org/uniprot/A0A2S1IF50 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1827580:DC008_RS28505 ^@ http://purl.uniprot.org/uniprot/A0A2S1IKV0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gas vesicle protein type A family.|||Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.|||gas vesicle membrane http://togogenome.org/gene/1827580:DC008_RS24720 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJ08 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1827580:DC008_RS20820 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGY6 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1827580:DC008_RS08605 ^@ http://purl.uniprot.org/uniprot/A0A2S1IAW3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/1827580:DC008_RS21935 ^@ http://purl.uniprot.org/uniprot/A0A2S1IHH5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family.|||Homotrimer.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine. http://togogenome.org/gene/1827580:DC008_RS10715 ^@ http://purl.uniprot.org/uniprot/A0A2S1ICK8 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1827580:DC008_RS13475 ^@ http://purl.uniprot.org/uniprot/A0A2S1IDB6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/1827580:DC008_RS20925 ^@ http://purl.uniprot.org/uniprot/A0A2S1IH02 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/1827580:DC008_RS14335 ^@ http://purl.uniprot.org/uniprot/A0A2S1IDT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SsgA family.|||Cell septum http://togogenome.org/gene/1827580:DC008_RS07085 ^@ http://purl.uniprot.org/uniprot/A0A2S1IA80 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1827580:DC008_RS30620 ^@ http://purl.uniprot.org/uniprot/A0A2S1IM14 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1827580:DC008_RS25660 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJF2 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/1827580:DC008_RS21130 ^@ http://purl.uniprot.org/uniprot/A0A2S1IHP2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1827580:DC008_RS32375 ^@ http://purl.uniprot.org/uniprot/A0A2S1IMU6 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1827580:DC008_RS06350 ^@ http://purl.uniprot.org/uniprot/A0A2S1I9R9 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1827580:DC008_RS24870 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJ56 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1827580:DC008_RS23985 ^@ http://purl.uniprot.org/uniprot/A0A2S1IIJ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/1827580:DC008_RS20880 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGZ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1827580:DC008_RS31925 ^@ http://purl.uniprot.org/uniprot/A0A2S1IMI0 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1827580:DC008_RS21895 ^@ http://purl.uniprot.org/uniprot/A0A2S1IHJ7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1827580:DC008_RS07995 ^@ http://purl.uniprot.org/uniprot/A0A2S1IAT0 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1827580:DC008_RS08510 ^@ http://purl.uniprot.org/uniprot/A0A2S1IAV0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1827580:DC008_RS24990 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJ21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/1827580:DC008_RS25200 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJ62 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ A probable RNA-binding protein.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm http://togogenome.org/gene/1827580:DC008_RS13035 ^@ http://purl.uniprot.org/uniprot/A0A2S1ID50 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1827580:DC008_RS16120 ^@ http://purl.uniprot.org/uniprot/A0A2S1IEM0 ^@ Similarity ^@ Belongs to the PhoU family.|||Belongs to the UPF0111 family. http://togogenome.org/gene/1827580:DC008_RS20940 ^@ http://purl.uniprot.org/uniprot/A0A2S1IH11 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1827580:DC008_RS05570 ^@ http://purl.uniprot.org/uniprot/A0A2S1I9B6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1827580:DC008_RS28545 ^@ http://purl.uniprot.org/uniprot/A0A2S1IKV4 ^@ Function|||Subcellular Location Annotation ^@ May play a structural or regulatory role in gas vesicle synthesis.|||Vesicle|||gas vesicle http://togogenome.org/gene/1827580:DC008_RS19340 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGA5 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/1827580:DC008_RS25070 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJ76 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/1827580:DC008_RS23160 ^@ http://purl.uniprot.org/uniprot/A0A2S1II80 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1827580:DC008_RS21415 ^@ http://purl.uniprot.org/uniprot/A0A2S1IHB9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/1827580:DC008_RS08765 ^@ http://purl.uniprot.org/uniprot/A0A2S1IAZ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/1827580:DC008_RS21710 ^@ http://purl.uniprot.org/uniprot/A0A2S1IHE1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1827580:DC008_RS25375 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJA2 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1827580:DC008_RS20800 ^@ http://purl.uniprot.org/uniprot/A0A2S1IH15 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/1827580:DC008_RS12125 ^@ http://purl.uniprot.org/uniprot/A0A2S1ID96 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbsD / FucU family. RbsD subfamily.|||Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.|||Cytoplasm|||Homodecamer. http://togogenome.org/gene/1827580:DC008_RS21720 ^@ http://purl.uniprot.org/uniprot/A0A2S1IHH7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1827580:DC008_RS08615 ^@ http://purl.uniprot.org/uniprot/A0A2S1IAX4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Involved in both the histidine and tryptophan biosynthetic pathways. http://togogenome.org/gene/1827580:DC008_RS05565 ^@ http://purl.uniprot.org/uniprot/A0A2S1I9H1 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/1827580:DC008_RS12310 ^@ http://purl.uniprot.org/uniprot/A0A2S1ICU9 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1827580:DC008_RS08625 ^@ http://purl.uniprot.org/uniprot/A0A2S1IAW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/1827580:DC008_RS20175 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGM0 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). http://togogenome.org/gene/1827580:DC008_RS20830 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGY5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1827580:DC008_RS22470 ^@ http://purl.uniprot.org/uniprot/A0A2S1IQ41 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1827580:DC008_RS20835 ^@ http://purl.uniprot.org/uniprot/A0A2S1IHJ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1827580:DC008_RS25290 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJB7 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1827580:DC008_RS24850 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJF6 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1827580:DC008_RS19595 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGG0 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/1827580:DC008_RS21160 ^@ http://purl.uniprot.org/uniprot/A0A2S1IH35 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1827580:DC008_RS12305 ^@ http://purl.uniprot.org/uniprot/A0A2S1ICU8 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1827580:DC008_RS04265 ^@ http://purl.uniprot.org/uniprot/A0A2S1I8X1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MurCDEF family. MurT subfamily.|||Forms a heterodimer with GatD.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue. http://togogenome.org/gene/1827580:DC008_RS25020 ^@ http://purl.uniprot.org/uniprot/A0A2S1IJ67 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1827580:DC008_RS07005 ^@ http://purl.uniprot.org/uniprot/A0A2S1IA38 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1827580:DC008_RS29790 ^@ http://purl.uniprot.org/uniprot/A0A2S1ILI8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the zinc-containing alcohol dehydrogenase family.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1827580:DC008_RS08790 ^@ http://purl.uniprot.org/uniprot/A0A2S1IAY9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1827580:DC008_RS17935 ^@ http://purl.uniprot.org/uniprot/A0A2S1IFK7 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/1827580:DC008_RS20720 ^@ http://purl.uniprot.org/uniprot/A0A2S1IGW8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1827580:DC008_RS14345 ^@ http://purl.uniprot.org/uniprot/A0A2S1IDX4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1827580:DC008_RS05460 ^@ http://purl.uniprot.org/uniprot/A0A2S1I9A1 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/1827580:DC008_RS23025 ^@ http://purl.uniprot.org/uniprot/A0A2S1II52 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||Nucleus|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1827580:DC008_RS14660 ^@ http://purl.uniprot.org/uniprot/A0A2S1IDX7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1827580:DC008_RS09165 ^@ http://purl.uniprot.org/uniprot/A0A2S1IB65 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/1827580:DC008_RS25295 ^@ http://purl.uniprot.org/uniprot/A0A2S1IQ85 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.