http://togogenome.org/gene/1821621:A8C75_RS01925 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU84 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS04975 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVX9 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1821621:A8C75_RS04155 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV82 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively. http://togogenome.org/gene/1821621:A8C75_RS13205 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0R2 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/1821621:A8C75_RS18750 ^@ http://purl.uniprot.org/uniprot/A0A1A9F373 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS09180 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXJ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS21510 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4M2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS19510 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2X1 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1821621:A8C75_RS02045 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET78 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/1821621:A8C75_RS02790 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUP2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS13755 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0M7 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS18190 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2W7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS20285 ^@ http://purl.uniprot.org/uniprot/A0A1A9F493 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the nucleoid occlusion factor SlmA family.|||Homodimer. Interacts with FtsZ.|||Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.|||nucleoid http://togogenome.org/gene/1821621:A8C75_RS00010 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET06 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/1821621:A8C75_RS17985 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1Y9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS16930 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1E5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS20265 ^@ http://purl.uniprot.org/uniprot/A0A1A9F332 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/1821621:A8C75_RS01515 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUD5 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS14795 ^@ http://purl.uniprot.org/uniprot/A0A1A9F092 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS05960 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS20485 ^@ http://purl.uniprot.org/uniprot/A0A1A9F365 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone-like protein H-NS family.|||nucleoid http://togogenome.org/gene/1821621:A8C75_RS17015 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1M4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS18610 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3G8 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1821621:A8C75_RS13945 ^@ http://purl.uniprot.org/uniprot/A0A1A9F046 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/1821621:A8C75_RS21375 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3M2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1821621:A8C75_RS02560 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUP8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family. ParE type 1 subfamily.|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/1821621:A8C75_RS03720 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUU0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS16705 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1A2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1821621:A8C75_RS00705 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU70 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/1821621:A8C75_RS22005 ^@ http://purl.uniprot.org/uniprot/A0A1A9F556 ^@ Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS09560 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX34 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS02325 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUT5 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/1821621:A8C75_RS21120 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4B2 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1821621:A8C75_RS20365 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4F7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1821621:A8C75_RS05685 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWA9 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/1821621:A8C75_RS14850 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0G3 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1821621:A8C75_RS15230 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0N5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS05205 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVW0 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/1821621:A8C75_RS19530 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2K5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS18865 ^@ http://purl.uniprot.org/uniprot/A0A1A9F395 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1821621:A8C75_RS09325 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXW9 ^@ Function|||Similarity ^@ Belongs to the DUF177 domain family.|||Plays a role in synthesis, processing and/or stability of 23S rRNA. http://togogenome.org/gene/1821621:A8C75_RS19675 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3P1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS19555 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3M1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS20200 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3A3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1821621:A8C75_RS00325 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU02 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS06175 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWS3 ^@ Function|||Similarity ^@ A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.|||Belongs to the NifU family. http://togogenome.org/gene/1821621:A8C75_RS17250 ^@ http://purl.uniprot.org/uniprot/A0A1A9F121 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/1821621:A8C75_RS22765 ^@ http://purl.uniprot.org/uniprot/A0A1A9F589 ^@ Function|||Similarity ^@ Belongs to the ParB family.|||Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication. http://togogenome.org/gene/1821621:A8C75_RS20110 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2V6 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/1821621:A8C75_RS16390 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1Z1 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/1821621:A8C75_RS01340 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETM5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/1821621:A8C75_RS05025 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWJ1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family.|||Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. http://togogenome.org/gene/1821621:A8C75_RS14025 ^@ http://purl.uniprot.org/uniprot/A0A1A9F003 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS05165 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVM4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/1821621:A8C75_RS06455 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXA9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/1821621:A8C75_RS14610 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZT7 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/1821621:A8C75_RS17440 ^@ http://purl.uniprot.org/uniprot/A0A1A9F160 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS17750 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2P4 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/1821621:A8C75_RS02020 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUX0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS13220 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5A8 ^@ Similarity ^@ Belongs to the SufE family.|||Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily. http://togogenome.org/gene/1821621:A8C75_RS00830 ^@ http://purl.uniprot.org/uniprot/A0A1A9F494 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS07585 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXX1 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1821621:A8C75_RS10855 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXR5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS05495 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS14930 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0W6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS04060 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW02 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/1821621:A8C75_RS21125 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4P7 ^@ Function|||Similarity ^@ Belongs to the MoaB/Mog family.|||May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/1821621:A8C75_RS21495 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4I2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1821621:A8C75_RS20740 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4M5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS04920 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4F3 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/1821621:A8C75_RS06450 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS11770 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial glucokinase family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS02295 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUF8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the arginase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide. http://togogenome.org/gene/1821621:A8C75_RS20645 ^@ http://purl.uniprot.org/uniprot/A0A1A9F394 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S33 family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS11575 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZI8 ^@ Similarity ^@ Belongs to the MbcT/ParT/Res family. http://togogenome.org/gene/1821621:A8C75_RS22515 ^@ http://purl.uniprot.org/uniprot/A0A1A9F518 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS07480 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWU1 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 3 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/1821621:A8C75_RS19740 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3Q2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.|||Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS12470 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ34 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1821621:A8C75_RS04210 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV93 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1821621:A8C75_RS04580 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVA8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS05770 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW29 ^@ Function|||Similarity ^@ Belongs to the RapZ-like family.|||Displays ATPase and GTPase activities. http://togogenome.org/gene/1821621:A8C75_RS22595 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4T4 ^@ Similarity ^@ Belongs to the IucA/IucC family. http://togogenome.org/gene/1821621:A8C75_RS04260 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVA7 ^@ Similarity ^@ Belongs to the type III secretion exporter family. http://togogenome.org/gene/1821621:A8C75_RS20255 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4D5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1821621:A8C75_RS22355 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3Z6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatB family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1821621:A8C75_RS19340 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2T7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS09705 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYX0 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/1821621:A8C75_RS22160 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5A6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DksA family.|||Cytoplasm|||Interacts directly with the RNA polymerase.|||Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. http://togogenome.org/gene/1821621:A8C75_RS10495 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYZ7 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS04495 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVW5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GlpE family.|||Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS15580 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0Y7 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS11105 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYG6 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/1821621:A8C75_RS05565 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVZ0 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS10925 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS07935 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWA2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.|||Binds 2 Zn(2+) ions per subunit.|||Monomer.|||Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. http://togogenome.org/gene/1821621:A8C75_RS01490 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUP9 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS19365 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2J5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS07990 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS22750 ^@ http://purl.uniprot.org/uniprot/A0A1A9F552 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS14445 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0E2 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/1821621:A8C75_RS18195 ^@ http://purl.uniprot.org/uniprot/A0A1A9F286 ^@ Similarity ^@ Belongs to the class-II fumarase/aspartase family. Aspartase subfamily. http://togogenome.org/gene/1821621:A8C75_RS18985 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2M8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS20635 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4K6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS19115 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5K4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/1821621:A8C75_RS16015 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1F6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/1821621:A8C75_RS19265 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2H6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1821621:A8C75_RS05100 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUT3 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/1821621:A8C75_RS23480 ^@ http://purl.uniprot.org/uniprot/A0A1A9F572 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane|||Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. http://togogenome.org/gene/1821621:A8C75_RS06560 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWZ4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS00680 ^@ http://purl.uniprot.org/uniprot/A0A1A9ESG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS05225 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVN3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/1821621:A8C75_RS21780 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3P4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS14270 ^@ http://purl.uniprot.org/uniprot/A0A1A9F183 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/1821621:A8C75_RS04150 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV11 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/1821621:A8C75_RS19060 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2E8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS09255 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY31 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/1821621:A8C75_RS06620 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXE0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS19910 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3Q1 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/1821621:A8C75_RS14010 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS02915 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS18520 ^@ http://purl.uniprot.org/uniprot/A0A1A9F254 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/1821621:A8C75_RS12770 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZC3 ^@ Similarity ^@ Belongs to the MEMO1 family. http://togogenome.org/gene/1821621:A8C75_RS00730 ^@ http://purl.uniprot.org/uniprot/A0A1A9ESH2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/1821621:A8C75_RS20470 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3F8 ^@ Function|||Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family.|||Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. http://togogenome.org/gene/1821621:A8C75_RS18710 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3I8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1821621:A8C75_RS04390 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVY0 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1821621:A8C75_RS08305 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5L1 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1821621:A8C75_RS03640 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS09440 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS21420 ^@ http://purl.uniprot.org/uniprot/A0A1A9F396 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1821621:A8C75_RS01900 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU03 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). http://togogenome.org/gene/1821621:A8C75_RS02635 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVB3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS13250 ^@ http://purl.uniprot.org/uniprot/A0A1A9F016 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS20705 ^@ http://purl.uniprot.org/uniprot/A0A1A9F356 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS19875 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3S4 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS14170 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0T4 ^@ Cofactor ^@ Binds 2 iron ions per subunit. http://togogenome.org/gene/1821621:A8C75_RS11400 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZR6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/1821621:A8C75_RS18280 ^@ http://purl.uniprot.org/uniprot/A0A1A9F225 ^@ Similarity ^@ Belongs to the peptidase S13 family. http://togogenome.org/gene/1821621:A8C75_RS11875 ^@ http://purl.uniprot.org/uniprot/A0A1A9F002 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS21065 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3D2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS19630 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2Y7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1821621:A8C75_RS15260 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1D8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.|||Cytoplasm|||Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). http://togogenome.org/gene/1821621:A8C75_RS12245 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ38 ^@ Similarity ^@ Belongs to the allantoicase family. http://togogenome.org/gene/1821621:A8C75_RS16900 ^@ http://purl.uniprot.org/uniprot/A0A1A9F285 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1821621:A8C75_RS01525 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU56 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.|||One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/1821621:A8C75_RS02290 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUU8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family.|||Binds 1 zinc or iron ion per subunit.|||Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS12365 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ13 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family.|||Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/1821621:A8C75_RS07865 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX69 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS04245 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS12950 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0I7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS12985 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZF9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/1821621:A8C75_RS02075 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUF4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.|||Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers. http://togogenome.org/gene/1821621:A8C75_RS01465 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUL0 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/1821621:A8C75_RS16775 ^@ http://purl.uniprot.org/uniprot/A0A1A9F251 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.|||Cytoplasm|||Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.|||Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/1821621:A8C75_RS05585 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWK0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmJ family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the guanosine in position 1516 of 16S rRNA. http://togogenome.org/gene/1821621:A8C75_RS18095 ^@ http://purl.uniprot.org/uniprot/A0A1A9F209 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/1821621:A8C75_RS01135 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETL3 ^@ Function|||Similarity ^@ Belongs to the ectoine synthase family.|||Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant. http://togogenome.org/gene/1821621:A8C75_RS09320 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYF2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YceF subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1821621:A8C75_RS12515 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ85 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/1821621:A8C75_RS03435 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV56 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS17505 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1P2 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/1821621:A8C75_RS18920 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3A6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS17550 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1K3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase. http://togogenome.org/gene/1821621:A8C75_RS16380 ^@ http://purl.uniprot.org/uniprot/A0A1A9F108 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1821621:A8C75_RS05730 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWX4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Cell inner membrane|||Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS02910 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUF9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS21380 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3H1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1821621:A8C75_RS09250 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYP4 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/1821621:A8C75_RS01685 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUQ7 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/1821621:A8C75_RS14290 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1B8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS18005 ^@ http://purl.uniprot.org/uniprot/A0A1A9F329 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS20490 ^@ http://purl.uniprot.org/uniprot/A0A1A9F320 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. http://togogenome.org/gene/1821621:A8C75_RS11220 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 1 family.|||Periplasm http://togogenome.org/gene/1821621:A8C75_RS00755 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3Z1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS04970 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone-like protein H-NS family.|||nucleoid http://togogenome.org/gene/1821621:A8C75_RS03830 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV14 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1821621:A8C75_RS04725 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS04475 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV88 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/1821621:A8C75_RS21155 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3I1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. http://togogenome.org/gene/1821621:A8C75_RS07625 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YejK family.|||nucleoid http://togogenome.org/gene/1821621:A8C75_RS05660 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVW3 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MobA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.|||Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. http://togogenome.org/gene/1821621:A8C75_RS01650 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU32 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1821621:A8C75_RS22265 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5C6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/1821621:A8C75_RS17270 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1K1 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/1821621:A8C75_RS16795 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1I8 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.|||Binds 2 nickel ions per subunit.|||Carbamylation allows a single lysine to coordinate two nickel ions.|||Carboxylation allows a single lysine to coordinate two nickel ions.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1821621:A8C75_RS19460 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2V7 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/1821621:A8C75_RS22290 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3Y6 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/1821621:A8C75_RS12370 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ72 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS04880 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWH4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the tryptophan 2,3-dioxygenase family.|||Binds 1 heme group per subunit.|||Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.|||Homotetramer. http://togogenome.org/gene/1821621:A8C75_RS11215 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS09550 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYZ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS12080 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYV9 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system. http://togogenome.org/gene/1821621:A8C75_RS06380 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVF5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.|||Binds 3 [4Fe-4S] clusters.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1821621:A8C75_RS00130 ^@ http://purl.uniprot.org/uniprot/A0A1A9ESZ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the aerobic coproporphyrinogen-III oxidase family.|||Cytoplasm|||Homodimer.|||Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. http://togogenome.org/gene/1821621:A8C75_RS05270 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWP2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II). http://togogenome.org/gene/1821621:A8C75_RS01755 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUV0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS22400 ^@ http://purl.uniprot.org/uniprot/A0A1A9F448 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.|||Single-chain monomer with multiple functions. http://togogenome.org/gene/1821621:A8C75_RS16980 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1F2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Periplasm http://togogenome.org/gene/1821621:A8C75_RS04955 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVG8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YciB family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. http://togogenome.org/gene/1821621:A8C75_RS01390 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETN4 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/1821621:A8C75_RS11780 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ23 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS04280 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVV7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmC/CycZ/HelC family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/1821621:A8C75_RS15155 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1T3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the vitamin-B12 independent methionine synthase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation. http://togogenome.org/gene/1821621:A8C75_RS21330 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3G1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1821621:A8C75_RS06130 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWV5 ^@ Similarity ^@ Belongs to the glutaredoxin family. Monothiol subfamily. http://togogenome.org/gene/1821621:A8C75_RS01555 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETP1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS02030 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUP3 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1821621:A8C75_RS21255 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3U6 ^@ Function ^@ Repressor involved in choline regulation of the bet genes.|||Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine. http://togogenome.org/gene/1821621:A8C75_RS21845 ^@ http://purl.uniprot.org/uniprot/A0A1A9F530 ^@ Similarity ^@ Belongs to the Rsd/AlgQ family. http://togogenome.org/gene/1821621:A8C75_RS22120 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3Z9 ^@ Function|||Similarity ^@ Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family. http://togogenome.org/gene/1821621:A8C75_RS00370 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETS7 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1821621:A8C75_RS06930 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX87 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS21810 ^@ http://purl.uniprot.org/uniprot/A0A1A9F455 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS01450 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETL9 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/1821621:A8C75_RS09340 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWZ7 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/1821621:A8C75_RS19780 ^@ http://purl.uniprot.org/uniprot/A0A1A9F403 ^@ Function ^@ Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. http://togogenome.org/gene/1821621:A8C75_RS05060 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVJ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS03335 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVE1 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/1821621:A8C75_RS15585 ^@ http://purl.uniprot.org/uniprot/A0A1A9F208 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS04365 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV66 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Binds 1 Mg(2+) ion per monomer.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/1821621:A8C75_RS09345 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXQ0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/1821621:A8C75_RS08120 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS20185 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3L6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS20750 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3B2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS19005 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2A5 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/1821621:A8C75_RS00550 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETM7 ^@ Function|||Similarity ^@ Belongs to the aldehyde dehydrogenase family. AstD subfamily.|||Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate. http://togogenome.org/gene/1821621:A8C75_RS17500 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1J3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS15395 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0R4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS00420 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET77 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/1821621:A8C75_RS08700 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXB5 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. http://togogenome.org/gene/1821621:A8C75_RS13185 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0M1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS02060 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU33 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/1821621:A8C75_RS04010 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVQ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FlgA family.|||Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.|||Periplasm http://togogenome.org/gene/1821621:A8C75_RS18155 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1I9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS22015 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4I3 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/1821621:A8C75_RS03240 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUK9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/1821621:A8C75_RS16460 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1Z3 ^@ Similarity ^@ Belongs to the outer membrane porin (Opr) (TC 1.B.25) family. http://togogenome.org/gene/1821621:A8C75_RS03715 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU47 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/1821621:A8C75_RS02965 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUG1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS00225 ^@ http://purl.uniprot.org/uniprot/A0A1A9ES78 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1821621:A8C75_RS11795 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY67 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/1821621:A8C75_RS20725 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3V8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS02340 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS05340 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP E family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS06215 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||Cell inner membrane http://togogenome.org/gene/1821621:A8C75_RS10780 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ37 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.|||Homodimer.|||Involved in phosphonate degradation. http://togogenome.org/gene/1821621:A8C75_RS17390 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2S0 ^@ Similarity ^@ Belongs to the SdhE FAD assembly factor family. http://togogenome.org/gene/1821621:A8C75_RS18550 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2E5 ^@ Similarity ^@ Belongs to the CvfB family. http://togogenome.org/gene/1821621:A8C75_RS12630 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0F8 ^@ Similarity ^@ Belongs to the bacterial PQQ dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS05290 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVM6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/1821621:A8C75_RS08340 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWH2 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS02010 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU24 ^@ Function|||Similarity ^@ In the C-terminal section; belongs to the aldehyde dehydrogenase family.|||In the N-terminal section; belongs to the proline dehydrogenase family.|||Oxidizes proline to glutamate for use as a carbon and nitrogen source. http://togogenome.org/gene/1821621:A8C75_RS08135 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXS0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS14555 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZS7 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS06415 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWZ9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS16175 ^@ http://purl.uniprot.org/uniprot/A0A1A9F272 ^@ Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS13160 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYY7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS01635 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUP6 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/1821621:A8C75_RS02925 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV47 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamA family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/1821621:A8C75_RS17485 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2X2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the band 7/mec-2 family. HflK subfamily.|||HflC and HflK could encode or regulate a protease.|||HflC and HflK may interact to form a multimeric complex.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS03695 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV78 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1821621:A8C75_RS13620 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZY5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS08355 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXB2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS21885 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3R5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/1821621:A8C75_RS00365 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET66 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1821621:A8C75_RS04455 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVH3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/1821621:A8C75_RS17515 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2U0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS03940 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVY2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS07500 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS15970 ^@ http://purl.uniprot.org/uniprot/A0A1A9F153 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS17955 ^@ http://purl.uniprot.org/uniprot/A0A1A9F318 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/1821621:A8C75_RS00245 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET09 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS17875 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1D9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS18715 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1U1 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1821621:A8C75_RS19580 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2L1 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS22675 ^@ http://purl.uniprot.org/uniprot/A0A1A9F497 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS20680 ^@ http://purl.uniprot.org/uniprot/A0A1A9F478 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS20040 ^@ http://purl.uniprot.org/uniprot/A0A1A9F490 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS12960 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZW9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.|||Binds 1 [4Fe-4S] cluster.|||DNA-dependent ATPase and 5'-3' DNA helicase. http://togogenome.org/gene/1821621:A8C75_RS15015 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0D1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS02625 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUL2 ^@ Similarity ^@ Belongs to the UPF0250 family. http://togogenome.org/gene/1821621:A8C75_RS20685 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3J5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS09420 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY63 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dsrC/tusE family.|||Cytoplasm|||Part of a sulfur-relay system. http://togogenome.org/gene/1821621:A8C75_RS22260 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4D0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/1821621:A8C75_RS19655 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2P3 ^@ Function|||Similarity ^@ Belongs to the cyanase family.|||Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. http://togogenome.org/gene/1821621:A8C75_RS17300 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2U4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PEPCase type 1 family.|||Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.|||Homotetramer. http://togogenome.org/gene/1821621:A8C75_RS22205 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4B9 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1821621:A8C75_RS11340 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXZ3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS13520 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZP8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS05305 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWP6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/1821621:A8C75_RS09280 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWY7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS22805 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5J2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/1821621:A8C75_RS05555 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVU3 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FBPase class 1 family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS04020 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW22 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1821621:A8C75_RS19190 ^@ http://purl.uniprot.org/uniprot/A0A1A9F238 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/1821621:A8C75_RS08760 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXC5 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. http://togogenome.org/gene/1821621:A8C75_RS19815 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2V0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS06360 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWZ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1821621:A8C75_RS13415 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0G2 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1821621:A8C75_RS19870 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5L9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the AceK family.|||Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS09230 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXM8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.|||Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.|||Homotetramer; dimer of dimers.|||Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate. http://togogenome.org/gene/1821621:A8C75_RS03025 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUN1 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/1821621:A8C75_RS02375 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU42 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1821621:A8C75_RS14325 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0K9 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1821621:A8C75_RS14070 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS07690 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX40 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/1821621:A8C75_RS03445 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV05 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/1821621:A8C75_RS19160 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3B6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS01665 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETT3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS16275 ^@ http://purl.uniprot.org/uniprot/A0A1A9F142 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1821621:A8C75_RS04520 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWB0 ^@ Domain|||Function|||Subcellular Location Annotation ^@ Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.|||Periplasm|||The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition. http://togogenome.org/gene/1821621:A8C75_RS15700 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0A3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP K family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS18760 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3J9 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/1821621:A8C75_RS17940 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1R4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS22100 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4X3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS22760 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4W6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS21370 ^@ http://purl.uniprot.org/uniprot/A0A1A9F384 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1821621:A8C75_RS07205 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX28 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/1821621:A8C75_RS21460 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4L2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS11405 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ59 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1821621:A8C75_RS16445 ^@ http://purl.uniprot.org/uniprot/A0A1A9F202 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS09890 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ01 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1821621:A8C75_RS14800 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0F1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS19720 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2Q0 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1821621:A8C75_RS04845 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVL4 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS03810 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVY3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS19215 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3C5 ^@ Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family. http://togogenome.org/gene/1821621:A8C75_RS21940 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3T2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-BBH/TMLD family.|||Catalyzes the formation of L-carnitine from gamma-butyrobetaine.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS13980 ^@ http://purl.uniprot.org/uniprot/A0A1A9F123 ^@ Function|||Similarity ^@ Belongs to the esterase D family.|||Serine hydrolase involved in the detoxification of formaldehyde. http://togogenome.org/gene/1821621:A8C75_RS20465 ^@ http://purl.uniprot.org/uniprot/A0A1A9F435 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS19525 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2P9 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/1821621:A8C75_RS09785 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY47 ^@ Function|||Similarity ^@ Belongs to the 3-oxoacid CoA-transferase family.|||CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. http://togogenome.org/gene/1821621:A8C75_RS07100 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS08145 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXJ2 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1821621:A8C75_RS01990 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUY9 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/1821621:A8C75_RS06420 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWH1 ^@ Function|||Similarity ^@ Belongs to the precorrin methyltransferase family.|||In the C-terminal section; belongs to the precorrin methyltransferase family.|||In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.|||Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. http://togogenome.org/gene/1821621:A8C75_RS07615 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWY6 ^@ Function|||Similarity ^@ Belongs to the TrhO family.|||Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs. http://togogenome.org/gene/1821621:A8C75_RS18800 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2V5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS01655 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUT1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1821621:A8C75_RS13565 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0X4 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/1821621:A8C75_RS21300 ^@ http://purl.uniprot.org/uniprot/A0A1A9F454 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS13555 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZX6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS22435 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4G1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS14275 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0J9 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1821621:A8C75_RS15625 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1K0 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/1821621:A8C75_RS05560 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVS1 ^@ Function|||Similarity ^@ Belongs to the MurCDEF family. Mpl subfamily.|||Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate. http://togogenome.org/gene/1821621:A8C75_RS09430 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXY8 ^@ Similarity ^@ Belongs to the DsrF/TusC family. http://togogenome.org/gene/1821621:A8C75_RS15170 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0F9 ^@ Similarity|||Subunit ^@ Belongs to the methylthioribose kinase family.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS12900 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0H6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS01795 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS07820 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW82 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48 family. BepA subfamily.|||Binds 1 zinc ion per subunit.|||Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.|||Periplasm http://togogenome.org/gene/1821621:A8C75_RS12315 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ62 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS00635 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET79 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS04115 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW11 ^@ Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. http://togogenome.org/gene/1821621:A8C75_RS12810 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0I1 ^@ Function|||Similarity ^@ Belongs to the folylpolyglutamate synthase family.|||Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. http://togogenome.org/gene/1821621:A8C75_RS01840 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETU8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS02975 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUM3 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS09115 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXI4 ^@ Similarity ^@ Belongs to the nitroreductase family. http://togogenome.org/gene/1821621:A8C75_RS00425 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETT6 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS14530 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1D4 ^@ PTM ^@ The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/1821621:A8C75_RS16915 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0W0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS21610 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3L3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1821621:A8C75_RS02465 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETG6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/1821621:A8C75_RS05265 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVW7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. FtsW subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell division. http://togogenome.org/gene/1821621:A8C75_RS03775 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUU2 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/1821621:A8C75_RS03705 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV45 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/1821621:A8C75_RS18705 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2H3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. Thiolase family.|||Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.|||Cytoplasm|||Heterotetramer of two alpha chains (FadB) and two beta chains (FadA). http://togogenome.org/gene/1821621:A8C75_RS06155 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVB5 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/1821621:A8C75_RS04275 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVJ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmB/CycW/HelB family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/1821621:A8C75_RS09615 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYZ9 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/1821621:A8C75_RS22410 ^@ http://purl.uniprot.org/uniprot/A0A1A9F407 ^@ Similarity ^@ Belongs to the pseudomonas-type ThrB family. http://togogenome.org/gene/1821621:A8C75_RS01580 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU67 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/1821621:A8C75_RS04300 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbE subfamily.|||Cell inner membrane http://togogenome.org/gene/1821621:A8C75_RS13615 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0H7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS03995 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVM3 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS19045 ^@ http://purl.uniprot.org/uniprot/A0A1A9F205 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/1821621:A8C75_RS06445 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS16740 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1H8 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1821621:A8C75_RS01405 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUB5 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1821621:A8C75_RS05550 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV19 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/1821621:A8C75_RS16030 ^@ http://purl.uniprot.org/uniprot/A0A1A9F267 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1821621:A8C75_RS21710 ^@ http://purl.uniprot.org/uniprot/A0A1A9F434 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure. http://togogenome.org/gene/1821621:A8C75_RS20595 ^@ http://purl.uniprot.org/uniprot/A0A1A9F339 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons. http://togogenome.org/gene/1821621:A8C75_RS10520 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYG3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1821621:A8C75_RS05375 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS16655 ^@ http://purl.uniprot.org/uniprot/A0A1A9F231 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/1821621:A8C75_RS02320 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU85 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1821621:A8C75_RS18200 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3A0 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/1821621:A8C75_RS19380 ^@ http://purl.uniprot.org/uniprot/A0A1A9F370 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. YhhS family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS17170 ^@ http://purl.uniprot.org/uniprot/A0A1A9F216 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1821621:A8C75_RS01745 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUJ0 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system. http://togogenome.org/gene/1821621:A8C75_RS01000 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETR5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inositol monophosphatase superfamily. CysQ family.|||Cell inner membrane|||Converts adenosine-3',5'-bisphosphate (PAP) to AMP. http://togogenome.org/gene/1821621:A8C75_RS04830 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUN7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS03485 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUP5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS02610 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUQ8 ^@ Function|||Similarity ^@ Belongs to the RlpA family.|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/1821621:A8C75_RS09935 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY08 ^@ Similarity ^@ Belongs to the nitroreductase family. http://togogenome.org/gene/1821621:A8C75_RS03155 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS05330 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUX5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Cell inner membrane|||Cell membrane|||Membrane|||Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine. http://togogenome.org/gene/1821621:A8C75_RS17860 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2R2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS08620 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYH0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS02410 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS02485 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUW6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/1821621:A8C75_RS14595 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0H1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/1821621:A8C75_RS05855 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV68 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/1821621:A8C75_RS22700 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5H2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS12095 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZS3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS00125 ^@ http://purl.uniprot.org/uniprot/A0A1A9ESZ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family. TsaC subfamily.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. http://togogenome.org/gene/1821621:A8C75_RS14075 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5M9 ^@ Similarity ^@ Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family. http://togogenome.org/gene/1821621:A8C75_RS08465 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXD4 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS01660 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET03 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1821621:A8C75_RS09855 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ40 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS17945 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1W6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptF/LptG family.|||Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).|||Membrane|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. http://togogenome.org/gene/1821621:A8C75_RS04745 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVI9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS02035 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUA4 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/1821621:A8C75_RS16145 ^@ http://purl.uniprot.org/uniprot/A0A1A9F293 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscS (TC 1.A.23) family.|||Cell inner membrane|||Homoheptamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS02805 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUD6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell outer membrane http://togogenome.org/gene/1821621:A8C75_RS07120 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWN0 ^@ Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.|||Belongs to the RecC family.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. http://togogenome.org/gene/1821621:A8C75_RS07230 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWQ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS19570 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2B0 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1821621:A8C75_RS17480 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1V8 ^@ Function|||Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily.|||HflC and HflK could regulate a protease. http://togogenome.org/gene/1821621:A8C75_RS21785 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3Q7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.|||Homotetramer. http://togogenome.org/gene/1821621:A8C75_RS16585 ^@ http://purl.uniprot.org/uniprot/A0A1A9F184 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M81 family.|||Binds 1 zinc ion per subunit.|||Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC). http://togogenome.org/gene/1821621:A8C75_RS20275 ^@ http://purl.uniprot.org/uniprot/A0A1A9F307 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/1821621:A8C75_RS18515 ^@ http://purl.uniprot.org/uniprot/A0A1A9F210 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/1821621:A8C75_RS04080 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/1821621:A8C75_RS20080 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3W7 ^@ Similarity ^@ Belongs to the bacterial secretin family. http://togogenome.org/gene/1821621:A8C75_RS05930 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVY8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS13880 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0M6 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/1821621:A8C75_RS21400 ^@ http://purl.uniprot.org/uniprot/A0A1A9F474 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1821621:A8C75_RS05080 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVZ6 ^@ Function|||Subunit ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).|||Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/1821621:A8C75_RS01670 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETR8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS00990 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETV6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PAPS reductase family. CysD subfamily.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/1821621:A8C75_RS01930 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUX7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/1821621:A8C75_RS03195 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV92 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS11855 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYX5 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/1821621:A8C75_RS04490 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4V5 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/1821621:A8C75_RS19635 ^@ http://purl.uniprot.org/uniprot/A0A1A9F413 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1821621:A8C75_RS12835 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZF4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS07200 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXP2 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS01215 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETU9 ^@ Function|||Similarity ^@ Belongs to the GlnE family.|||Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell. http://togogenome.org/gene/1821621:A8C75_RS06065 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX32 ^@ Similarity ^@ Belongs to the flavin oxidoreductase frp family. http://togogenome.org/gene/1821621:A8C75_RS17140 ^@ http://purl.uniprot.org/uniprot/A0A1A9F100 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/1821621:A8C75_RS21500 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4W9 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1821621:A8C75_RS03305 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUL9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS21480 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3P3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1821621:A8C75_RS00655 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETP6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS03325 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVM8 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/1821621:A8C75_RS02135 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS03455 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU08 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/1821621:A8C75_RS14035 ^@ http://purl.uniprot.org/uniprot/A0A1A9F139 ^@ Cofactor|||Similarity ^@ Belongs to the RimK family.|||Binds 2 magnesium or manganese ions per subunit. http://togogenome.org/gene/1821621:A8C75_RS20715 ^@ http://purl.uniprot.org/uniprot/A0A1A9F442 ^@ Similarity ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family. http://togogenome.org/gene/1821621:A8C75_RS15065 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0D9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inositol monophosphatase superfamily. CysQ family.|||Cell inner membrane|||Converts adenosine-3',5'-bisphosphate (PAP) to AMP. http://togogenome.org/gene/1821621:A8C75_RS18365 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2B9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS05850 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX01 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/1821621:A8C75_RS17195 ^@ http://purl.uniprot.org/uniprot/A0A1A9F111 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/1821621:A8C75_RS21670 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3R8 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/1821621:A8C75_RS04375 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVV0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS00100 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETD9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Cytoplasm|||Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. http://togogenome.org/gene/1821621:A8C75_RS11765 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZY1 ^@ Similarity ^@ Belongs to the glucose-6-phosphate 1-epimerase family. http://togogenome.org/gene/1821621:A8C75_RS06265 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW81 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. http://togogenome.org/gene/1821621:A8C75_RS03755 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV50 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1821621:A8C75_RS11110 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYL7 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS16075 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1G6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS21405 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4K2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1821621:A8C75_RS00760 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU79 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS09455 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXP0 ^@ Function|||Similarity ^@ Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.|||Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. http://togogenome.org/gene/1821621:A8C75_RS22465 ^@ http://purl.uniprot.org/uniprot/A0A1A9F506 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family.|||Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.|||Cell inner membrane http://togogenome.org/gene/1821621:A8C75_RS04570 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWC1 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/1821621:A8C75_RS10035 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXY6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS16875 ^@ http://purl.uniprot.org/uniprot/A0A1A9F187 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS21995 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3U2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/1821621:A8C75_RS05390 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVR5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1821621:A8C75_RS15930 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0T1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS04420 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV71 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1821621:A8C75_RS11665 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZY6 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1821621:A8C75_RS07605 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4I8 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/1821621:A8C75_RS04555 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVP1 ^@ Function|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.|||Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. http://togogenome.org/gene/1821621:A8C75_RS21205 ^@ http://purl.uniprot.org/uniprot/A0A1A9F351 ^@ Similarity ^@ Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family. http://togogenome.org/gene/1821621:A8C75_RS05480 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW68 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS03955 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV91 ^@ Cofactor ^@ Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/1821621:A8C75_RS11310 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZE7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxH family.|||Belongs to the metallophosphoesterase superfamily. YfcE family.|||Binds 2 Mn(2+) ions per subunit in a binuclear metal center.|||Cell inner membrane|||Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS04995 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWJ5 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1821621:A8C75_RS20290 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3N6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS10085 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY23 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS05020 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS05515 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS01540 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0J2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS21520 ^@ http://purl.uniprot.org/uniprot/A0A1A9F485 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1821621:A8C75_RS00410 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0382 family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS13810 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0N7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS07320 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS18160 ^@ http://purl.uniprot.org/uniprot/A0A1A9F219 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/1821621:A8C75_RS21240 ^@ http://purl.uniprot.org/uniprot/A0A1A9F696 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1821621:A8C75_RS11320 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ50 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS02505 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUZ1 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS14890 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1N3 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1821621:A8C75_RS07740 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXB9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS04940 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWI6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||In the N-terminal section; belongs to the FGAMS family.|||Monomer.|||Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. http://togogenome.org/gene/1821621:A8C75_RS01715 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETU6 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS10940 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ76 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS13030 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4U8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS22155 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4A9 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1821621:A8C75_RS15635 ^@ http://purl.uniprot.org/uniprot/A0A1A9F211 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS02025 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUE2 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/1821621:A8C75_RS15315 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0U3 ^@ Similarity ^@ Belongs to the DNA photolyase class-1 family.|||Belongs to the DNA photolyase family. http://togogenome.org/gene/1821621:A8C75_RS08160 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY73 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/1821621:A8C75_RS22135 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4U3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS13410 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZQ1 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1821621:A8C75_RS15030 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1N2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/1821621:A8C75_RS17025 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0Y1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS03505 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV61 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS17455 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1M5 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. http://togogenome.org/gene/1821621:A8C75_RS18580 ^@ http://purl.uniprot.org/uniprot/A0A1A9F264 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1821621:A8C75_RS21685 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4L4 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Involved in a late step of protoheme IX synthesis.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS18150 ^@ http://purl.uniprot.org/uniprot/A0A1A9F390 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS20550 ^@ http://purl.uniprot.org/uniprot/A0A1A9F414 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS09700 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYJ5 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.|||In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/1821621:A8C75_RS22460 ^@ http://purl.uniprot.org/uniprot/A0A1A9F419 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiC family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway. http://togogenome.org/gene/1821621:A8C75_RS05590 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW28 ^@ Similarity ^@ Belongs to the GPAT/DAPAT family. http://togogenome.org/gene/1821621:A8C75_RS21560 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3K0 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/1821621:A8C75_RS01395 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETK9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS22795 ^@ http://purl.uniprot.org/uniprot/A0A1A9F477 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS03600 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUS0 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/1821621:A8C75_RS15200 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1C5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.|||Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).|||Binds 1 Mg(2+) ion per subunit.|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS01730 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUH2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS01590 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU22 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS04030 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1821621:A8C75_RS16820 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1D1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreD family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/1821621:A8C75_RS07700 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW60 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TER reductase family.|||Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS16355 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1X7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/1821621:A8C75_RS18815 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2J8 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Belongs to the peroxiredoxin family. Prx6 subfamily. http://togogenome.org/gene/1821621:A8C75_RS06315 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVE4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1821621:A8C75_RS15345 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0Q4 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/1821621:A8C75_RS17930 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1F0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the glyoxalase I family.|||Binds 1 nickel ion per subunit.|||Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. http://togogenome.org/gene/1821621:A8C75_RS12595 ^@ http://purl.uniprot.org/uniprot/A0A1A9F013 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS02130 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUG3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1821621:A8C75_RS05250 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWN4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/1821621:A8C75_RS02050 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU04 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS01115 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUH7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M15D family.|||Binds 1 zinc ion per subunit.|||Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. http://togogenome.org/gene/1821621:A8C75_RS11045 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXU4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/1821621:A8C75_RS00630 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET86 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-I family. http://togogenome.org/gene/1821621:A8C75_RS05040 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVS9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS14420 ^@ http://purl.uniprot.org/uniprot/A0A1A9F112 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS22165 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3L5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon. http://togogenome.org/gene/1821621:A8C75_RS12670 ^@ http://purl.uniprot.org/uniprot/A0A1A9F023 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PqqD family.|||Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.|||Monomer. Interacts with PqqE. http://togogenome.org/gene/1821621:A8C75_RS02500 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUN4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbC subfamily.|||Periplasm|||Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. http://togogenome.org/gene/1821621:A8C75_RS07890 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX38 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NfuA family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.|||Homodimer.|||Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. http://togogenome.org/gene/1821621:A8C75_RS04065 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVE6 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Secreted http://togogenome.org/gene/1821621:A8C75_RS10175 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZA1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS21550 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3B3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS06660 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWF0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS20865 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3D1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS16725 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2F8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS17175 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2E4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/1821621:A8C75_RS07595 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW40 ^@ Similarity ^@ Belongs to the PhzF family. http://togogenome.org/gene/1821621:A8C75_RS13540 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0U4 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1821621:A8C75_RS16995 ^@ http://purl.uniprot.org/uniprot/A0A1A9F288 ^@ PTM ^@ Binds 1 heme group per subunit. http://togogenome.org/gene/1821621:A8C75_RS04410 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUG2 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/1821621:A8C75_RS03540 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUW4 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/1821621:A8C75_RS04485 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVE2 ^@ Function|||Similarity ^@ Belongs to the HPPK family.|||Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway. http://togogenome.org/gene/1821621:A8C75_RS10600 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYC8 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/1821621:A8C75_RS19165 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3N9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS20145 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4B1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS14295 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZM7 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. DsdA subfamily. http://togogenome.org/gene/1821621:A8C75_RS19080 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3D4 ^@ Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/1821621:A8C75_RS04135 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS07470 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXU9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RlmKL family.|||Cytoplasm|||Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. http://togogenome.org/gene/1821621:A8C75_RS20960 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3Z5 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the MsrP family.|||Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.|||Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).|||Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.|||Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven. http://togogenome.org/gene/1821621:A8C75_RS04025 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUA1 ^@ Function|||Similarity ^@ Belongs to the FlgD family.|||Required for flagellar hook formation. May act as a scaffolding protein. http://togogenome.org/gene/1821621:A8C75_RS21040 ^@ http://purl.uniprot.org/uniprot/A0A1A9F6K5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/1821621:A8C75_RS22535 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4S2 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/1821621:A8C75_RS14310 ^@ http://purl.uniprot.org/uniprot/A0A1A9F061 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/1821621:A8C75_RS20830 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4J1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS06180 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX57 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/1821621:A8C75_RS07805 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX60 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/1821621:A8C75_RS12210 ^@ http://purl.uniprot.org/uniprot/A0A1A9F059 ^@ Function|||Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.|||Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate. http://togogenome.org/gene/1821621:A8C75_RS09390 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX04 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 1 family.|||Belongs to the LDH/MDH superfamily. MDH type 2 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/1821621:A8C75_RS18215 ^@ http://purl.uniprot.org/uniprot/A0A1A9F223 ^@ Function ^@ Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site. http://togogenome.org/gene/1821621:A8C75_RS00575 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET75 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1821621:A8C75_RS17530 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1W8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-to-5' exoribonuclease specific for small oligoribonucleotides.|||Belongs to the oligoribonuclease family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS07770 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWV3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/1821621:A8C75_RS12865 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0J8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1821621:A8C75_RS18860 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2W5 ^@ Similarity ^@ Belongs to the PrpF family. http://togogenome.org/gene/1821621:A8C75_RS06385 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW99 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1821621:A8C75_RS04285 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5C4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmD/CycX/HelD family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/1821621:A8C75_RS15905 ^@ http://purl.uniprot.org/uniprot/A0A1A9F145 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/1821621:A8C75_RS07405 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX55 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS17465 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2T1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1821621:A8C75_RS07015 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWH6 ^@ Similarity ^@ Belongs to the transposase 8 family. http://togogenome.org/gene/1821621:A8C75_RS10570 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYZ8 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/1821621:A8C75_RS12205 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HflD family.|||Cell membrane|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS21770 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3F1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS12215 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZJ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS00475 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET87 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS01890 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETV8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HemJ family.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS12870 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYT6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS12790 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0F6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the trans-sulfuration enzymes family. MetZ subfamily.|||Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.|||Homotetramer. http://togogenome.org/gene/1821621:A8C75_RS12125 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYD1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrcB (TC 9.B.71) family.|||Cell membrane|||Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS16770 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1C0 ^@ Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. http://togogenome.org/gene/1821621:A8C75_RS06230 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWT4 ^@ Similarity ^@ Belongs to the HMG-CoA reductase family. http://togogenome.org/gene/1821621:A8C75_RS11430 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4R6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS00320 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETR6 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Member of a two-component regulatory system. http://togogenome.org/gene/1821621:A8C75_RS17340 ^@ http://purl.uniprot.org/uniprot/A0A1A9F243 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS19310 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2G0 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family. http://togogenome.org/gene/1821621:A8C75_RS17165 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2N0 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1821621:A8C75_RS12795 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZT8 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS10490 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYA6 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS16635 ^@ http://purl.uniprot.org/uniprot/A0A1A9F194 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS07530 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWV0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/1821621:A8C75_RS19755 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2E3 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1821621:A8C75_RS04185 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW53 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell inner membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS08645 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXG1 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/1821621:A8C75_RS13355 ^@ http://purl.uniprot.org/uniprot/A0A1A9F035 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 51 family.|||Cell inner membrane|||Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. http://togogenome.org/gene/1821621:A8C75_RS14340 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1C6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS04670 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWE1 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/1821621:A8C75_RS01940 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETY3 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/1821621:A8C75_RS10950 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZJ0 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/1821621:A8C75_RS12610 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZR2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS21250 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4G9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS21980 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3X8 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/1821621:A8C75_RS16530 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5R6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. METTL16/RlmF family.|||Cytoplasm|||Specifically methylates the adenine in position 1618 of 23S rRNA. http://togogenome.org/gene/1821621:A8C75_RS11235 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZD6 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1821621:A8C75_RS18780 ^@ http://purl.uniprot.org/uniprot/A0A1A9F268 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1821621:A8C75_RS19350 ^@ http://purl.uniprot.org/uniprot/A0A1A9F271 ^@ Similarity ^@ Belongs to the extradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/1821621:A8C75_RS05650 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWW7 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS00570 ^@ http://purl.uniprot.org/uniprot/A0A1A9ESD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS04220 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW33 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/1821621:A8C75_RS01105 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU71 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Homodimer.|||Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. http://togogenome.org/gene/1821621:A8C75_RS05065 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVP9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS05155 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWM6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AFG1 ATPase family. ZapE subfamily.|||Cytoplasm|||Interacts with FtsZ.|||Reduces the stability of FtsZ polymers in the presence of ATP. http://togogenome.org/gene/1821621:A8C75_RS06355 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWM4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/1821621:A8C75_RS01850 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUJ7 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/1821621:A8C75_RS07955 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXN7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.|||Cell membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/1821621:A8C75_RS16835 ^@ http://purl.uniprot.org/uniprot/A0A1A9F513 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS05230 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/1821621:A8C75_RS19100 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3R2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LolB family.|||Cell outer membrane|||Membrane|||Monomer.|||Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. http://togogenome.org/gene/1821621:A8C75_RS21665 ^@ http://purl.uniprot.org/uniprot/A0A1A9F584 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm|||In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily. http://togogenome.org/gene/1821621:A8C75_RS01410 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUK0 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1821621:A8C75_RS05810 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVZ7 ^@ Similarity ^@ Belongs to the SIS family. GutQ/KpsF subfamily. http://togogenome.org/gene/1821621:A8C75_RS22545 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4H9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS21265 ^@ http://purl.uniprot.org/uniprot/A0A1A9F363 ^@ Function|||Similarity ^@ Belongs to the GMC oxidoreductase family.|||Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. http://togogenome.org/gene/1821621:A8C75_RS21090 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3Q9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thioester dehydratase family. FabA subfamily.|||Cytoplasm|||Homodimer.|||Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. http://togogenome.org/gene/1821621:A8C75_RS10470 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXI7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS05865 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW07 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/1821621:A8C75_RS06390 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW66 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/1821621:A8C75_RS13050 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZD8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.|||Belongs to the azoreductase type 1 family.|||Binds 1 FMN per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones. http://togogenome.org/gene/1821621:A8C75_RS03500 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVQ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GcdB/MmdB/OadB family.|||Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.|||Cell membrane|||Heterotrimer of an alpha, a beta and a gamma subunit.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS17830 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1P7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS13990 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0P6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS10300 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS02830 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUV2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/1821621:A8C75_RS08725 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS19665 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3Y3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS04810 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVU4 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. http://togogenome.org/gene/1821621:A8C75_RS14885 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0M4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/1821621:A8C75_RS16645 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1A0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS04990 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4G6 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. UbiG/COQ3 family.|||O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. http://togogenome.org/gene/1821621:A8C75_RS19520 ^@ http://purl.uniprot.org/uniprot/A0A1A9F296 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS12185 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ28 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1821621:A8C75_RS19065 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3A7 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1821621:A8C75_RS08280 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX43 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/1821621:A8C75_RS01825 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET35 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the malate synthase family. GlcB subfamily.|||Cytoplasm|||Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS13150 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZQ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RdgC family.|||May be involved in recombination.|||nucleoid http://togogenome.org/gene/1821621:A8C75_RS13260 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZS6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS03460 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUQ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/1821621:A8C75_RS13965 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZT9 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family. Prx5 subfamily.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1821621:A8C75_RS11550 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS13720 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0J7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Cob(I)alamin adenosyltransferase family.|||Cytoplasm|||Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. http://togogenome.org/gene/1821621:A8C75_RS14970 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0I4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS07610 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWS4 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS19360 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2H0 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1821621:A8C75_RS04295 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS05985 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW62 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS04050 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4H8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgI family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/1821621:A8C75_RS03820 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUV9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS03945 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVC4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS08155 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXB8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/1821621:A8C75_RS22285 ^@ http://purl.uniprot.org/uniprot/A0A1A9F425 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/1821621:A8C75_RS14490 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0Z5 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS22195 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4L1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/1821621:A8C75_RS21640 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4P8 ^@ Function|||Similarity|||Subunit ^@ Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.|||Belongs to the ZapA family. Type 1 subfamily.|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/1821621:A8C75_RS07760 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS06120 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS21475 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3A4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1821621:A8C75_RS09435 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DsrE/TusD family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS15555 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1K2 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/1821621:A8C75_RS04585 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVA4 ^@ Similarity ^@ Belongs to the D-glutamate cyclase family. http://togogenome.org/gene/1821621:A8C75_RS08030 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXH3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||Membrane|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/1821621:A8C75_RS04040 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV64 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1821621:A8C75_RS09945 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ09 ^@ Function|||Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family.|||Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. http://togogenome.org/gene/1821621:A8C75_RS02810 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS01910 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUU5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS12675 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0D8 ^@ Function|||Similarity ^@ Belongs to the PqqC family.|||Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ. http://togogenome.org/gene/1821621:A8C75_RS12195 ^@ http://purl.uniprot.org/uniprot/A0A1A9F663 ^@ Similarity|||Subunit ^@ Belongs to the Nudix hydrolase family. NudJ subfamily.|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS20575 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3H6 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1821621:A8C75_RS07105 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWT9 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS09545 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY07 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS14925 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1K5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS09410 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYF0 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/1821621:A8C75_RS07225 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVW8 ^@ Caution|||Function|||Similarity ^@ Belongs to the Dus family. DusA subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS08860 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY79 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1821621:A8C75_RS03095 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV03 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/1821621:A8C75_RS17890 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4V3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/1821621:A8C75_RS06980 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWY8 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS10075 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ81 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1821621:A8C75_RS04360 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV52 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/1821621:A8C75_RS02540 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU77 ^@ Function|||Similarity ^@ Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.|||Belongs to the Nudix hydrolase family. NudF subfamily. http://togogenome.org/gene/1821621:A8C75_RS13165 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZI9 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/1821621:A8C75_RS07985 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX88 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.|||Cytoplasm|||Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. http://togogenome.org/gene/1821621:A8C75_RS00645 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETX5 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1821621:A8C75_RS12160 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZI2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1821621:A8C75_RS21620 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4K4 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/1821621:A8C75_RS17295 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1S9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS02945 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUS3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxA subfamily.|||Cytoplasm|||Homotrimer.|||Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/1821621:A8C75_RS19085 ^@ http://purl.uniprot.org/uniprot/A0A1A9F6I0 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/1821621:A8C75_RS01005 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUF6 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS02900 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVH8 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS06150 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX54 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1821621:A8C75_RS14900 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0F0 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1821621:A8C75_RS18950 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2A2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS18030 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1G9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EamA transporter family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS20905 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4K1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS16330 ^@ http://purl.uniprot.org/uniprot/A0A1A9F155 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS13645 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZU1 ^@ Similarity ^@ Belongs to the GST superfamily. Zeta family. http://togogenome.org/gene/1821621:A8C75_RS02620 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV10 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1821621:A8C75_RS00750 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETZ5 ^@ Function|||Similarity ^@ Belongs to the Fe(2+)-trafficking protein family.|||Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. http://togogenome.org/gene/1821621:A8C75_RS00020 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETV1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1821621:A8C75_RS05950 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWF8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/1821621:A8C75_RS17470 ^@ http://purl.uniprot.org/uniprot/A0A1A9F263 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.|||This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one. http://togogenome.org/gene/1821621:A8C75_RS05705 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV41 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1821621:A8C75_RS00390 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETF9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/1821621:A8C75_RS10530 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXJ7 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1821621:A8C75_RS02985 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVH5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsB family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/1821621:A8C75_RS04195 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV25 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliN/MopA/SpaO family.|||Cell membrane|||FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS01495 ^@ http://purl.uniprot.org/uniprot/A0A1A9ESX4 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS20585 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2V2 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. http://togogenome.org/gene/1821621:A8C75_RS00595 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETW5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. UvrD subfamily.|||Homodimer.|||Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. http://togogenome.org/gene/1821621:A8C75_RS09235 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXK1 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1821621:A8C75_RS05575 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWU4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS04680 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVC7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/1821621:A8C75_RS21590 ^@ http://purl.uniprot.org/uniprot/A0A1A9F405 ^@ Function|||Similarity ^@ Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.|||Belongs to the Nudix hydrolase family. RppH subfamily. http://togogenome.org/gene/1821621:A8C75_RS09055 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXK4 ^@ Similarity ^@ Belongs to the CbbQ/NirQ/NorQ/GpvN family. http://togogenome.org/gene/1821621:A8C75_RS21050 ^@ http://purl.uniprot.org/uniprot/A0A1A9F325 ^@ Function|||Similarity ^@ Belongs to the ribF family.|||Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. http://togogenome.org/gene/1821621:A8C75_RS08525 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYD8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS15370 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0V7 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1821621:A8C75_RS17010 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2B3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS00585 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETA7 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/1821621:A8C75_RS09970 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXA1 ^@ PTM ^@ The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/1821621:A8C75_RS13475 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZR0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS11605 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYZ3 ^@ Similarity ^@ Belongs to the DNA polymerase type-Y family. http://togogenome.org/gene/1821621:A8C75_RS19120 ^@ http://purl.uniprot.org/uniprot/A0A1A9F218 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/1821621:A8C75_RS06260 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVD3 ^@ Similarity ^@ Belongs to the DNA polymerase type-B family. http://togogenome.org/gene/1821621:A8C75_RS12750 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZI4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1821621:A8C75_RS11135 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYR8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS05540 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW13 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the zinc-containing alcohol dehydrogenase family.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1821621:A8C75_RS04125 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS17770 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1V1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS17200 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1J7 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/1821621:A8C75_RS15725 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1M7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS14320 ^@ http://purl.uniprot.org/uniprot/A0A1A9F193 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RlmJ family.|||Monomer.|||Specifically methylates the adenine in position 2030 of 23S rRNA. http://togogenome.org/gene/1821621:A8C75_RS17075 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2Q5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS20520 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3G6 ^@ Similarity ^@ Belongs to the phosphate/phosphite/phosphonate binding protein family. http://togogenome.org/gene/1821621:A8C75_RS05215 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUV3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS02070 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUX8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/1821621:A8C75_RS14210 ^@ http://purl.uniprot.org/uniprot/A0A1A9F171 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS21505 ^@ http://purl.uniprot.org/uniprot/A0A1A9F495 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/1821621:A8C75_RS00490 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETL7 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/1821621:A8C75_RS13230 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZG2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS21565 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3M0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS11865 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYY4 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).|||Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS19035 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2N8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS08035 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXT5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||Membrane|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/1821621:A8C75_RS03605 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUR4 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/1821621:A8C75_RS21660 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3D3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS21410 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3X4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1821621:A8C75_RS14065 ^@ http://purl.uniprot.org/uniprot/A0A1A9F168 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS05795 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW63 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptA family.|||Component of the lipopolysaccharide transport and assembly complex.|||Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.|||Periplasm http://togogenome.org/gene/1821621:A8C75_RS21225 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4D1 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1821621:A8C75_RS17350 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1T8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS17765 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1B7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS06615 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX06 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS21880 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3W0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1821621:A8C75_RS09265 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYE2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS15115 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0E9 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/1821621:A8C75_RS18915 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2X6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS12255 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ52 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/1821621:A8C75_RS05300 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWB4 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/1821621:A8C75_RS20870 ^@ http://purl.uniprot.org/uniprot/A0A1A9F382 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS12715 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS22000 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4S1 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/1821621:A8C75_RS18740 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3G4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS22040 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3Y9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS11610 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZX5 ^@ Similarity ^@ Belongs to the peptidase S24 family. http://togogenome.org/gene/1821621:A8C75_RS02845 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVG2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1821621:A8C75_RS06135 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWB8 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. http://togogenome.org/gene/1821621:A8C75_RS14220 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0U8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS00090 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TrkH potassium transport family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS01620 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETV0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1821621:A8C75_RS16790 ^@ http://purl.uniprot.org/uniprot/A0A1A9F265 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UreE family.|||Cytoplasm|||Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. http://togogenome.org/gene/1821621:A8C75_RS22390 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5E6 ^@ PTM ^@ Binds 2 heme c groups covalently per subunit. http://togogenome.org/gene/1821621:A8C75_RS11140 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS16660 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2F1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aldehyde dehydrogenase family.|||Binds 2 potassium ions per subunit.|||Dimer of dimers.|||Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS00565 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU69 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1821621:A8C75_RS01385 ^@ http://purl.uniprot.org/uniprot/A0A1A9ESV2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. http://togogenome.org/gene/1821621:A8C75_RS18770 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4W4 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS03365 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUT6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS06605 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWA5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/1821621:A8C75_RS17920 ^@ http://purl.uniprot.org/uniprot/A0A1A9F235 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/1821621:A8C75_RS02300 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV46 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS10330 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYX2 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/1821621:A8C75_RS05715 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVU7 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1821621:A8C75_RS12825 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4K9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1821621:A8C75_RS10795 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXQ4 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS17430 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1U8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamB family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/1821621:A8C75_RS04595 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVY4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS22315 ^@ http://purl.uniprot.org/uniprot/A0A1A9F514 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/1821621:A8C75_RS07745 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXN5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS01520 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUM2 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS01110 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETT4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/1821621:A8C75_RS17320 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1L1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/1821621:A8C75_RS22215 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3M5 ^@ Similarity ^@ Belongs to the PTPS family. QueD subfamily. http://togogenome.org/gene/1821621:A8C75_RS03610 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUX4 ^@ Function ^@ The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/1821621:A8C75_RS00870 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETG2 ^@ Function ^@ Repressor involved in choline regulation of the bet genes.|||Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine. http://togogenome.org/gene/1821621:A8C75_RS13110 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZH9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CcoP / FixP family.|||Binds 2 heme C groups per subunit.|||C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.|||Cell inner membrane|||Component of the cbb3-type cytochrome c oxidase. http://togogenome.org/gene/1821621:A8C75_RS17375 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1H2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1821621:A8C75_RS21135 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4F5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Binds 1 Mg(2+) ion per monomer.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/1821621:A8C75_RS04865 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW67 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS20335 ^@ http://purl.uniprot.org/uniprot/A0A1A9F317 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS04250 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV36 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/1821621:A8C75_RS07830 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS12740 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZS8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS18890 ^@ http://purl.uniprot.org/uniprot/A0A1A9F290 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS21210 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3J3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS20985 ^@ http://purl.uniprot.org/uniprot/A0A1A9F316 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/1821621:A8C75_RS04870 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVQ3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS07980 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXS3 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/1821621:A8C75_RS22615 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3U0 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1821621:A8C75_RS08840 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXI5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS18410 ^@ http://purl.uniprot.org/uniprot/A0A1A9F309 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/1821621:A8C75_RS13700 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0L7 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. http://togogenome.org/gene/1821621:A8C75_RS06285 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX79 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity ^@ Belongs to the globin family. Two-domain flavohemoproteins subfamily.|||Binds 1 FAD per subunit.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.|||Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS16695 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2H9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1821621:A8C75_RS21085 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4E6 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1821621:A8C75_RS08180 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX86 ^@ Similarity ^@ Belongs to the UPF0260 family. http://togogenome.org/gene/1821621:A8C75_RS00075 ^@ http://purl.uniprot.org/uniprot/A0A1A9ESX8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1821621:A8C75_RS01330 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUL8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Cell inner membrane|||Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. http://togogenome.org/gene/1821621:A8C75_RS12250 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYZ2 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/1821621:A8C75_RS03665 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUS2 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/1821621:A8C75_RS02255 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU45 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS13335 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZI7 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1821621:A8C75_RS00005 ^@ http://purl.uniprot.org/uniprot/A0A1A9ESW8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/1821621:A8C75_RS13390 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4X1 ^@ Function|||Similarity|||Subunit ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily.|||Interacts with MinC and FtsZ. http://togogenome.org/gene/1821621:A8C75_RS02125 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUZ3 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1821621:A8C75_RS13590 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZS9 ^@ Similarity ^@ Belongs to the N-acylglucosamine 2-epimerase family. http://togogenome.org/gene/1821621:A8C75_RS09645 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYW0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS00670 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETK6 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS07155 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS01700 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU43 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS08295 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXV2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS15755 ^@ http://purl.uniprot.org/uniprot/A0A1A9F227 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS13235 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZL9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS13145 ^@ http://purl.uniprot.org/uniprot/A0A1A9F095 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS02990 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUY0 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruD family.|||Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs. http://togogenome.org/gene/1821621:A8C75_RS12420 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ90 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS21105 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3H0 ^@ Similarity ^@ Belongs to the MoaD family. http://togogenome.org/gene/1821621:A8C75_RS20500 ^@ http://purl.uniprot.org/uniprot/A0A1A9F406 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS20560 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4E5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/1821621:A8C75_RS12175 ^@ http://purl.uniprot.org/uniprot/A0A1A9F076 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS12410 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ67 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the malate synthase family. GlcB subfamily.|||Cytoplasm|||Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS00765 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETR7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS21840 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4P3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell inner membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS05275 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUW5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS11000 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYE8 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS06975 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4J5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS19535 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2M3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS07790 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXY9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TolB family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||Periplasm|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/1821621:A8C75_RS00660 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETZ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS02085 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUB3 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/1821621:A8C75_RS19320 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3E6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1821621:A8C75_RS15440 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0P9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS00080 ^@ http://purl.uniprot.org/uniprot/A0A1A9ESX9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1821621:A8C75_RS17315 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1G2 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1821621:A8C75_RS09350 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXM1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS00110 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETA6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1821621:A8C75_RS22590 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5F1 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/1821621:A8C75_RS13735 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZA0 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1821621:A8C75_RS03645 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS10605 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ21 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS21260 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4W0 ^@ Function|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.|||Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids. http://togogenome.org/gene/1821621:A8C75_RS21470 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4Z9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1821621:A8C75_RS02380 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU95 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1821621:A8C75_RS19495 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3V4 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/1821621:A8C75_RS00720 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETL6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/1821621:A8C75_RS17635 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2M5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0394 family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS16155 ^@ http://purl.uniprot.org/uniprot/A0A1A9F109 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1821621:A8C75_RS12415 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ24 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1821621:A8C75_RS11815 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZM6 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1821621:A8C75_RS13195 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0A8 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/1821621:A8C75_RS20315 ^@ http://purl.uniprot.org/uniprot/A0A1A9F563 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinylarginine dihydrolase family.|||Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS06855 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWK7 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1821621:A8C75_RS05260 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWE0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS09295 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXQ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class II aldolase/RraA-like family.|||Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.|||Homotrimer. http://togogenome.org/gene/1821621:A8C75_RS16190 ^@ http://purl.uniprot.org/uniprot/A0A1A9F192 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1821621:A8C75_RS20720 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4H1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS13865 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0P7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS05915 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX11 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/1821621:A8C75_RS20945 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3B8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Binds a copper A center.|||Cell membrane|||Membrane|||Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). http://togogenome.org/gene/1821621:A8C75_RS03125 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUJ6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS05475 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWS2 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/1821621:A8C75_RS11265 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZB6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS22720 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5K8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1821621:A8C75_RS16420 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0N0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS08625 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4M6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS01070 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETH5 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS00215 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS02955 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETS1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/1821621:A8C75_RS18460 ^@ http://purl.uniprot.org/uniprot/A0A1A9F321 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1821621:A8C75_RS02475 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU66 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/1821621:A8C75_RS05325 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWQ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS06160 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW59 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS12580 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ94 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS16640 ^@ http://purl.uniprot.org/uniprot/A0A1A9F148 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS00120 ^@ http://purl.uniprot.org/uniprot/A0A1A9ES54 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/1821621:A8C75_RS00140 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETN8 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/1821621:A8C75_RS16810 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1C2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS00210 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETR0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS00900 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETP5 ^@ Cofactor|||Similarity ^@ Belongs to the monomeric-type IDH family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/1821621:A8C75_RS21045 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4S0 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS12920 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0K7 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/1821621:A8C75_RS16010 ^@ http://purl.uniprot.org/uniprot/A0A1A9F241 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1821621:A8C75_RS21455 ^@ http://purl.uniprot.org/uniprot/A0A1A9F485 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1821621:A8C75_RS12940 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZH5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS05355 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWC4 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/1821621:A8C75_RS02895 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUR5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS20735 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3K4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS00250 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell outer membrane http://togogenome.org/gene/1821621:A8C75_RS21730 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3N4 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HSP33 family.|||Cytoplasm|||Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.|||Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive. http://togogenome.org/gene/1821621:A8C75_RS17050 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2A3 ^@ Similarity ^@ Belongs to the cysteine dioxygenase family. http://togogenome.org/gene/1821621:A8C75_RS19180 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2Q7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane|||Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).|||The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. http://togogenome.org/gene/1821621:A8C75_RS05760 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVY7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS21315 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4W8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/1821621:A8C75_RS07270 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWW9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS20065 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3T5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS02600 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUZ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/1821621:A8C75_RS22560 ^@ http://purl.uniprot.org/uniprot/A0A1A9F476 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/1821621:A8C75_RS05535 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWI9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS18070 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2H1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS19765 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2N9 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1821621:A8C75_RS19670 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3C7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS24040 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3T7 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/1821621:A8C75_RS12495 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZY0 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1821621:A8C75_RS18830 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2D7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS11940 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0060 family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS22780 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3X0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/1821621:A8C75_RS22080 ^@ http://purl.uniprot.org/uniprot/A0A1A9F565 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HesB/IscA family.|||Binds 1 iron-sulfur cluster per subunit.|||Homodimer.|||Required for insertion of 4Fe-4S clusters for at least IspG. http://togogenome.org/gene/1821621:A8C75_RS19890 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2G3 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/1821621:A8C75_RS21450 ^@ http://purl.uniprot.org/uniprot/A0A1A9F507 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1821621:A8C75_RS12965 ^@ http://purl.uniprot.org/uniprot/A0A1A9F064 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/1821621:A8C75_RS05185 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5D3 ^@ Similarity ^@ Belongs to the GST superfamily. HSP26 family. http://togogenome.org/gene/1821621:A8C75_RS07450 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXT1 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/1821621:A8C75_RS22510 ^@ http://purl.uniprot.org/uniprot/A0A1A9F427 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS00015 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETL8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/1821621:A8C75_RS20505 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4D4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS15860 ^@ http://purl.uniprot.org/uniprot/A0A1A9F237 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Gfo/Idh/MocA family.|||Homotetramer.|||Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose). http://togogenome.org/gene/1821621:A8C75_RS12190 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYY0 ^@ Similarity|||Subunit ^@ Belongs to the MoaE family.|||Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis. http://togogenome.org/gene/1821621:A8C75_RS21110 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3C0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/1821621:A8C75_RS03795 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV95 ^@ Caution|||Function|||Similarity ^@ Belongs to the bacterial two-domain DSD family.|||Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS05735 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWB9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1821621:A8C75_RS13010 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZX9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.|||Cytoplasm|||Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity. http://togogenome.org/gene/1821621:A8C75_RS15820 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0V2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS17520 ^@ http://purl.uniprot.org/uniprot/A0A1A9F273 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS04085 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUB2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/1821621:A8C75_RS02950 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVJ1 ^@ Function|||Similarity ^@ Belongs to the LpxB family.|||Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/1821621:A8C75_RS21740 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4M7 ^@ Similarity ^@ Belongs to the HSP15 family. http://togogenome.org/gene/1821621:A8C75_RS10355 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZC8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS17905 ^@ http://purl.uniprot.org/uniprot/A0A1A9F308 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF2.|||Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. http://togogenome.org/gene/1821621:A8C75_RS02685 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUM1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LptE lipoprotein family.|||Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.|||Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. http://togogenome.org/gene/1821621:A8C75_RS06125 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWI8 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/1821621:A8C75_RS08200 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXW8 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/1821621:A8C75_RS10850 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZL2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS13650 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0K8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS06840 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVP2 ^@ Similarity ^@ Belongs to the pyrroline-5-carboxylate reductase family. http://togogenome.org/gene/1821621:A8C75_RS09490 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXZ4 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/1821621:A8C75_RS02430 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUA5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS07235 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWL3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS05320 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVX7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DNA gyrase inhibitor YacG family.|||Binds 1 zinc ion.|||Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.|||Interacts with GyrB. http://togogenome.org/gene/1821621:A8C75_RS08755 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXF6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS18145 ^@ http://purl.uniprot.org/uniprot/A0A1A9F549 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. http://togogenome.org/gene/1821621:A8C75_RS19405 ^@ http://purl.uniprot.org/uniprot/A0A1A9F577 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1821621:A8C75_RS18325 ^@ http://purl.uniprot.org/uniprot/A0A1A9F248 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS08020 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXP9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrB/RnfD family.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/1821621:A8C75_RS12030 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ10 ^@ Similarity ^@ Belongs to the YoeB family. http://togogenome.org/gene/1821621:A8C75_RS12490 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZP1 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1821621:A8C75_RS22730 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4A6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1821621:A8C75_RS02175 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV02 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS06335 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWB7 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. http://togogenome.org/gene/1821621:A8C75_RS20345 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4A2 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. http://togogenome.org/gene/1821621:A8C75_RS09290 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXK9 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/1821621:A8C75_RS02890 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV62 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1821621:A8C75_RS12020 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ05 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/1821621:A8C75_RS00695 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS02115 ^@ http://purl.uniprot.org/uniprot/A0A1A9F408 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the GTP cyclohydrolase II family.|||Binds 1 zinc ion per subunit.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. http://togogenome.org/gene/1821621:A8C75_RS06540 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVI7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS04935 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVQ8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase Slt family.|||Cell outer membrane|||In the C-terminal section; belongs to the transglycosylase Slt family.|||In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.|||Membrane|||Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.|||The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain. http://togogenome.org/gene/1821621:A8C75_RS06460 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWP0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein PotD/PotF family.|||Periplasm|||Required for the activity of the bacterial periplasmic transport system of putrescine. http://togogenome.org/gene/1821621:A8C75_RS02000 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETZ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Catalyzes the sodium-dependent uptake of extracellular L-proline.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS02730 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUS6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/1821621:A8C75_RS18100 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1U4 ^@ Similarity ^@ Belongs to the DinB family. http://togogenome.org/gene/1821621:A8C75_RS19605 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3X3 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/1821621:A8C75_RS17280 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2Q4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.|||Cytoplasm|||Specifically methylates the ribose of guanosine 2251 in 23S rRNA. http://togogenome.org/gene/1821621:A8C75_RS01130 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETG5 ^@ Function|||Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.|||Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate. http://togogenome.org/gene/1821621:A8C75_RS17825 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1V9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS15960 ^@ http://purl.uniprot.org/uniprot/A0A1A9F6D4 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/1821621:A8C75_RS15400 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1I0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS12680 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZR8 ^@ Function|||Similarity ^@ Belongs to the PqqB family.|||May be involved in the transport of PQQ or its precursor to the periplasm. http://togogenome.org/gene/1821621:A8C75_RS07725 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS18415 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2C5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.|||Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.|||Cytoplasm|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS20900 ^@ http://purl.uniprot.org/uniprot/A0A1A9F472 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS20230 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3W2 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1821621:A8C75_RS21195 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3T4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ureidoglycolate lyase family.|||Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS09120 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXM7 ^@ Function|||Subunit ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).|||Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/1821621:A8C75_RS18880 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1X4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TamA family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS21690 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4Z5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS01585 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS17420 ^@ http://purl.uniprot.org/uniprot/A0A1A9F253 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/1821621:A8C75_RS12860 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZK4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1821621:A8C75_RS05945 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX12 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1821621:A8C75_RS14030 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0T3 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/1821621:A8C75_RS20305 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4E7 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/1821621:A8C75_RS03875 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUW0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS11880 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS00505 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETH8 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/1821621:A8C75_RS22235 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4W5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/1821621:A8C75_RS05030 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVY5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/1821621:A8C75_RS20170 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4Y6 ^@ Function|||Similarity ^@ Belongs to the TenA family.|||Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. http://togogenome.org/gene/1821621:A8C75_RS04175 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS09515 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXU2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.|||Cytoplasm|||Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. http://togogenome.org/gene/1821621:A8C75_RS22540 ^@ http://purl.uniprot.org/uniprot/A0A1A9F553 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/1821621:A8C75_RS07800 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXP4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CpoB family.|||Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.|||Periplasm http://togogenome.org/gene/1821621:A8C75_RS05010 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVI0 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS03670 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS21080 ^@ http://purl.uniprot.org/uniprot/A0A1A9F415 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/1821621:A8C75_RS03085 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV76 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/1821621:A8C75_RS06170 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW88 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/1821621:A8C75_RS21835 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3R6 ^@ Similarity ^@ Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. http://togogenome.org/gene/1821621:A8C75_RS09475 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS23810 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXF1 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1821621:A8C75_RS08095 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS13510 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ60 ^@ Similarity|||Subunit ^@ Belongs to the muconolactone Delta-isomerase family.|||Homodecamer. http://togogenome.org/gene/1821621:A8C75_RS13820 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0B6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS14655 ^@ http://purl.uniprot.org/uniprot/A0A1A9F6B4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS07695 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXZ0 ^@ Similarity ^@ Belongs to the ModE family. http://togogenome.org/gene/1821621:A8C75_RS13095 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0N8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Binds 1 copper ion per subunit, denoted as copper B.|||Binds 2 heme groups per subunit, denoted as high- and low-spin.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS12155 ^@ http://purl.uniprot.org/uniprot/A0A1A9F049 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the R-transferase family. Bpt subfamily.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. http://togogenome.org/gene/1821621:A8C75_RS13675 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0Z6 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1821621:A8C75_RS21655 ^@ http://purl.uniprot.org/uniprot/A0A1A9F524 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS08955 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXK5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/1821621:A8C75_RS17605 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1S0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS03950 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVP5 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS10975 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZM8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS02920 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS12785 ^@ http://purl.uniprot.org/uniprot/A0A1A9F042 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/1821621:A8C75_RS02390 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV42 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/1821621:A8C75_RS07145 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXN2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS12320 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZW7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS02385 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUU6 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1821621:A8C75_RS08015 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX58 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NqrA family.|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/1821621:A8C75_RS22645 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4U4 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/1821621:A8C75_RS14355 ^@ http://purl.uniprot.org/uniprot/A0A1A9F017 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS16685 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4T3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/1821621:A8C75_RS03235 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUL5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). http://togogenome.org/gene/1821621:A8C75_RS00735 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS03615 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVF3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Heterodimer of an alpha and a beta chain.|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/1821621:A8C75_RS01205 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETZ6 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/1821621:A8C75_RS18335 ^@ http://purl.uniprot.org/uniprot/A0A1A9F230 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS08490 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXJ0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS12285 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZT6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS00380 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETJ6 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. RsmD family.|||Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle. http://togogenome.org/gene/1821621:A8C75_RS19425 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2I3 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1821621:A8C75_RS04740 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVD0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS13200 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0761 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS02650 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU97 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS16140 ^@ http://purl.uniprot.org/uniprot/A0A1A9F181 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the peroxidase family. Peroxidase/catalase subfamily.|||Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.|||Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS14525 ^@ http://purl.uniprot.org/uniprot/A0A1A9F127 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1821621:A8C75_RS16160 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0X0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS16625 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2H2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS21575 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4X8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS09200 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY22 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS20220 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2X4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS12380 ^@ http://purl.uniprot.org/uniprot/A0A1A9F085 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS09675 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX51 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS22035 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3J7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS06990 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWS1 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS04200 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV23 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliO/MopB family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS06375 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX95 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell inner membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1821621:A8C75_RS22745 ^@ http://purl.uniprot.org/uniprot/A0A1A9F465 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS11965 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYZ5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS01125 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETI5 ^@ Function|||Similarity ^@ Belongs to the acetyltransferase family. EctA subfamily.|||Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A. http://togogenome.org/gene/1821621:A8C75_RS01935 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET55 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1821621:A8C75_RS22710 ^@ http://purl.uniprot.org/uniprot/A0A1A9F579 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family. http://togogenome.org/gene/1821621:A8C75_RS04510 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW00 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/1821621:A8C75_RS12450 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0C5 ^@ Similarity ^@ Belongs to the RuBisCO large chain family. http://togogenome.org/gene/1821621:A8C75_RS03140 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS07390 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWU6 ^@ Similarity ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family. http://togogenome.org/gene/1821621:A8C75_RS14415 ^@ http://purl.uniprot.org/uniprot/A0A1A9F081 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/1821621:A8C75_RS11035 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYP7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS17865 ^@ http://purl.uniprot.org/uniprot/A0A1A9F222 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS17160 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2B8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/1821621:A8C75_RS14400 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZP7 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS01865 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS04730 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUL7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS09190 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYB2 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1821621:A8C75_RS05920 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV74 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/1821621:A8C75_RS16065 ^@ http://purl.uniprot.org/uniprot/A0A1A9F252 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1821621:A8C75_RS04015 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVA1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/1821621:A8C75_RS22255 ^@ http://purl.uniprot.org/uniprot/A0A1A9F504 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/1821621:A8C75_RS02735 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV31 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/1821621:A8C75_RS19625 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3N1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS02455 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUI2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS04350 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW80 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS15390 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0J3 ^@ Cofactor|||Similarity ^@ Belongs to the nitroreductase family.|||Binds 1 FMN per subunit. http://togogenome.org/gene/1821621:A8C75_RS17245 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4U2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS22550 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5H5 ^@ Cofactor|||Similarity ^@ Belongs to the 4HPPD family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/1821621:A8C75_RS17970 ^@ http://purl.uniprot.org/uniprot/A0A1A9F247 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1821621:A8C75_RS07765 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWZ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/1821621:A8C75_RS07685 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXM5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1821621:A8C75_RS14565 ^@ http://purl.uniprot.org/uniprot/A0A1A9F051 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 2 family.|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases.|||Periplasm|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/1821621:A8C75_RS17650 ^@ http://purl.uniprot.org/uniprot/A0A1A9F198 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 104 family.|||Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes. http://togogenome.org/gene/1821621:A8C75_RS02235 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS20630 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3I6 ^@ Similarity ^@ Belongs to the N-acylglucosamine 2-epimerase family. http://togogenome.org/gene/1821621:A8C75_RS14990 ^@ http://purl.uniprot.org/uniprot/A0A1A9F186 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.|||Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). http://togogenome.org/gene/1821621:A8C75_RS02365 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETE3 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/1821621:A8C75_RS02720 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV09 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS21175 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4Q2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.|||Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).|||Homotetramer. http://togogenome.org/gene/1821621:A8C75_RS14700 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1G3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 1 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/1821621:A8C75_RS07515 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX07 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/1821621:A8C75_RS13070 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0K3 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1821621:A8C75_RS03300 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUM5 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/1821621:A8C75_RS19820 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2Q1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/1821621:A8C75_RS15020 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0J0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS21875 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3G9 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/1821621:A8C75_RS09995 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS15730 ^@ http://purl.uniprot.org/uniprot/A0A1A9F207 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.|||Belongs to the GSP E family.|||Cell inner membrane http://togogenome.org/gene/1821621:A8C75_RS20610 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4F6 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/1821621:A8C75_RS16095 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0H2 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1821621:A8C75_RS11315 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZQ3 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1821621:A8C75_RS04930 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW77 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS01800 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUA6 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/1821621:A8C75_RS20380 ^@ http://purl.uniprot.org/uniprot/A0A1A9F349 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 7 family.|||Homodimer.|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||Periplasm http://togogenome.org/gene/1821621:A8C75_RS21060 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3B0 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1821621:A8C75_RS16780 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2G7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreF family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/1821621:A8C75_RS11065 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0E2 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/1821621:A8C75_RS12115 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ78 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/1821621:A8C75_RS11565 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYM2 ^@ Function|||Similarity ^@ Belongs to the gamma-glutamylcyclotransferase family.|||Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides. http://togogenome.org/gene/1821621:A8C75_RS06425 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXA7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS01155 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU82 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/1821621:A8C75_RS06190 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWW5 ^@ Function|||Similarity ^@ Belongs to the heat shock protein 70 family.|||Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. http://togogenome.org/gene/1821621:A8C75_RS16495 ^@ http://purl.uniprot.org/uniprot/A0A1A9F177 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS19255 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2E7 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1821621:A8C75_RS12340 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZB4 ^@ Cofactor|||Similarity ^@ Belongs to the 4HPPD family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/1821621:A8C75_RS02760 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUB7 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.|||May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA. http://togogenome.org/gene/1821621:A8C75_RS02590 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU87 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/1821621:A8C75_RS03210 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVC1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS17915 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2S1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS01345 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETK1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS17355 ^@ http://purl.uniprot.org/uniprot/A0A1A9F540 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/1821621:A8C75_RS09275 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYU4 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/1821621:A8C75_RS15195 ^@ http://purl.uniprot.org/uniprot/A0A1A9F115 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the acireductone dioxygenase (ARD) family.|||Binds 1 Fe(2+) cation per monomer.|||Binds 1 nickel ion per monomer.|||Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS05805 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV60 ^@ Function|||Similarity|||Subunit ^@ Belongs to the KdsC family.|||Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.|||Homotetramer. http://togogenome.org/gene/1821621:A8C75_RS03895 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVB6 ^@ Function|||Similarity ^@ Belongs to the AlaDH/PNT family.|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/1821621:A8C75_RS08045 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY52 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ApbE family.|||Cell inner membrane|||Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.|||Magnesium. Can also use manganese. http://togogenome.org/gene/1821621:A8C75_RS20135 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3Y1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M81 family.|||Binds 1 zinc ion per subunit.|||Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC). http://togogenome.org/gene/1821621:A8C75_RS15055 ^@ http://purl.uniprot.org/uniprot/A0A1A9F008 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS21755 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4R7 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/1821621:A8C75_RS12375 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZX4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS12730 ^@ http://purl.uniprot.org/uniprot/A0A1A9F032 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LPG synthase family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS18555 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3F9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. http://togogenome.org/gene/1821621:A8C75_RS02090 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV08 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). http://togogenome.org/gene/1821621:A8C75_RS15680 ^@ http://purl.uniprot.org/uniprot/A0A1A9F195 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial secretin family. GSP D subfamily.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS15010 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0H0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS22755 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5I2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS09680 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXV4 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/1821621:A8C75_RS04055 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVN4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.|||In the C-terminal section; belongs to the glycosyl hydrolase 73 family.|||In the N-terminal section; belongs to the FlgJ family.|||Periplasm http://togogenome.org/gene/1821621:A8C75_RS14720 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0J2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS08675 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY50 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/1821621:A8C75_RS07520 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXW2 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/1821621:A8C75_RS05160 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUU3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1821621:A8C75_RS08055 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX45 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS15605 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0T7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS03725 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUT2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS19170 ^@ http://purl.uniprot.org/uniprot/A0A1A9F326 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1821621:A8C75_RS12850 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZU8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS02995 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV81 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/1821621:A8C75_RS05015 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVN7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS01045 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETW7 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family. http://togogenome.org/gene/1821621:A8C75_RS22655 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4K0 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/1821621:A8C75_RS16100 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0Z8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS04305 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV48 ^@ Function|||Similarity ^@ Belongs to the CcmH/CycL/Ccl2/NrfF family.|||Possible subunit of a heme lyase. http://togogenome.org/gene/1821621:A8C75_RS04230 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVU6 ^@ Function|||Similarity ^@ Belongs to the GTP-binding SRP family.|||Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. http://togogenome.org/gene/1821621:A8C75_RS12390 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZV6 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters.|||Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. http://togogenome.org/gene/1821621:A8C75_RS06105 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW17 ^@ Similarity ^@ Belongs to the class-II DAHP synthase family. http://togogenome.org/gene/1821621:A8C75_RS17490 ^@ http://purl.uniprot.org/uniprot/A0A1A9F169 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/1821621:A8C75_RS19550 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3A2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS19240 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3T6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS21075 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4N6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1821621:A8C75_RS13005 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0J5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS05070 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW75 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 7 family.|||Homodimer.|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||Periplasm http://togogenome.org/gene/1821621:A8C75_RS03215 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5P4 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/1821621:A8C75_RS01915 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUC3 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/1821621:A8C75_RS09630 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXR8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Vgb family.|||Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid.|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS19750 ^@ http://purl.uniprot.org/uniprot/A0A1A9F431 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/1821621:A8C75_RS01860 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUB6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS19305 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2L4 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. http://togogenome.org/gene/1821621:A8C75_RS20910 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3Y5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS19435 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3G5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS02785 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV44 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein S18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS16405 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1Y3 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS04575 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUJ3 ^@ Cofactor|||Function ^@ Accepts electrons from ETF and reduces ubiquinone.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/1821621:A8C75_RS20955 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4L5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MsrQ family.|||Binds 1 FMN per subunit.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Cell membrane|||Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).|||Membrane|||Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain. http://togogenome.org/gene/1821621:A8C75_RS05765 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVV8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS00055 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4N0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS18575 ^@ http://purl.uniprot.org/uniprot/A0A1A9F220 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS20650 ^@ http://purl.uniprot.org/uniprot/A0A1A9F350 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS04470 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5G7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/1821621:A8C75_RS16975 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0X2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS04205 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4F0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/1821621:A8C75_RS11150 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYM0 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/1821621:A8C75_RS10095 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY37 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1821621:A8C75_RS12425 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZY7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS22380 ^@ http://purl.uniprot.org/uniprot/A0A1A9F525 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC1 family. UbiB subfamily.|||Cell membrane|||Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS16840 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1V0 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS24170 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV00 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/1821621:A8C75_RS02585 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUA2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/1821621:A8C75_RS17190 ^@ http://purl.uniprot.org/uniprot/A0A1A9F6H0 ^@ Similarity ^@ Belongs to the transcriptional regulatory Fis family. http://togogenome.org/gene/1821621:A8C75_RS05785 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWC8 ^@ Function|||Similarity ^@ Belongs to the sigma-54 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1821621:A8C75_RS05965 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS05335 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS03815 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU62 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/1821621:A8C75_RS01505 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETN1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/1821621:A8C75_RS07900 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY11 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1821621:A8C75_RS19760 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2U1 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/1821621:A8C75_RS08165 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWE3 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/1821621:A8C75_RS11670 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY45 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/1821621:A8C75_RS08185 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXT3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family.|||Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. http://togogenome.org/gene/1821621:A8C75_RS08205 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXD2 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1821621:A8C75_RS21485 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3I9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/1821621:A8C75_RS13730 ^@ http://purl.uniprot.org/uniprot/A0A1A9F107 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/1821621:A8C75_RS19770 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2R5 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1821621:A8C75_RS12705 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYQ3 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/1821621:A8C75_RS18400 ^@ http://purl.uniprot.org/uniprot/A0A1A9F399 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/1821621:A8C75_RS10345 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYW2 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1821621:A8C75_RS10645 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY92 ^@ Similarity ^@ Belongs to the EndA/NucM nuclease family. http://togogenome.org/gene/1821621:A8C75_RS01460 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUC5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS13385 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0U2 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/1821621:A8C75_RS20350 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3P6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecB family.|||Cytoplasm|||Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.|||One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. http://togogenome.org/gene/1821621:A8C75_RS02370 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU63 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/1821621:A8C75_RS17460 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2G9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/1821621:A8C75_RS12150 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZT4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/1821621:A8C75_RS12855 ^@ http://purl.uniprot.org/uniprot/A0A1A9F041 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS08990 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWT8 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1821621:A8C75_RS02580 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETI6 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/1821621:A8C75_RS22245 ^@ http://purl.uniprot.org/uniprot/A0A1A9F588 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/1821621:A8C75_RS04290 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVF1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmE/CycJ family.|||Cell membrane|||Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. http://togogenome.org/gene/1821621:A8C75_RS14345 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZN6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS14910 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0H3 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1821621:A8C75_RS10090 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXZ5 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1821621:A8C75_RS21320 ^@ http://purl.uniprot.org/uniprot/A0A1A9F372 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1821621:A8C75_RS04430 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVV9 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/1821621:A8C75_RS13505 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0W5 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/1821621:A8C75_RS17655 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1T0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS20270 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2Y4 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS02740 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUN2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS22305 ^@ http://purl.uniprot.org/uniprot/A0A1A9F599 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/1821621:A8C75_RS14765 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0T8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS18960 ^@ http://purl.uniprot.org/uniprot/A0A1A9F636 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS15060 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0I0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS02345 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUV8 ^@ Similarity ^@ Belongs to the ribosome association toxin RatA family. http://togogenome.org/gene/1821621:A8C75_RS14535 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0Q1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS06610 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWG4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 7 family.|||Homodimer.|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||Periplasm http://togogenome.org/gene/1821621:A8C75_RS02905 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETR1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1821621:A8C75_RS12545 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZP9 ^@ Similarity ^@ Belongs to the class I fructose-bisphosphate aldolase family. http://togogenome.org/gene/1821621:A8C75_RS11410 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZD5 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1821621:A8C75_RS08610 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY40 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/1821621:A8C75_RS04560 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW10 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/1821621:A8C75_RS21395 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4U7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1821621:A8C75_RS22725 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3W1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/1821621:A8C75_RS08735 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5Y7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS04005 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVD4 ^@ Function|||Similarity ^@ Belongs to the FlgM family.|||Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA. http://togogenome.org/gene/1821621:A8C75_RS11520 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYS4 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1821621:A8C75_RS11365 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZF3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS03290 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVQ1 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS00775 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS21390 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4G3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1821621:A8C75_RS10540 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY72 ^@ Function|||Similarity ^@ Belongs to the esterase D family.|||Serine hydrolase involved in the detoxification of formaldehyde. http://togogenome.org/gene/1821621:A8C75_RS12910 ^@ http://purl.uniprot.org/uniprot/A0A1A9F050 ^@ Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.|||Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue. http://togogenome.org/gene/1821621:A8C75_RS06400 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS00865 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETC2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aldehyde dehydrogenase family.|||Binds 2 potassium ions per subunit.|||Dimer of dimers.|||Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS03845 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVA6 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/1821621:A8C75_RS22350 ^@ http://purl.uniprot.org/uniprot/A0A1A9F438 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1821621:A8C75_RS11555 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY25 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/1821621:A8C75_RS02565 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUZ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.|||Cell membrane|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/1821621:A8C75_RS21350 ^@ http://purl.uniprot.org/uniprot/A0A1A9F464 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1821621:A8C75_RS04695 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW08 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/1821621:A8C75_RS05170 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVK6 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Rieske iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster per subunit.|||Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.|||Membrane|||The Rieske protein is a high potential 2Fe-2S protein.|||The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein. http://togogenome.org/gene/1821621:A8C75_RS12120 ^@ http://purl.uniprot.org/uniprot/A0A1A9F066 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS12280 ^@ http://purl.uniprot.org/uniprot/A0A1A9F591 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/1821621:A8C75_RS01325 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS06490 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWC0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS09795 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX71 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS17225 ^@ http://purl.uniprot.org/uniprot/A0A1A9F226 ^@ Similarity ^@ Belongs to the UPF0229 family. http://togogenome.org/gene/1821621:A8C75_RS05090 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVT6 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS00270 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETZ4 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/1821621:A8C75_RS18855 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3I5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS14365 ^@ http://purl.uniprot.org/uniprot/A0A1A9F102 ^@ Similarity ^@ Belongs to the agmatine deiminase family. http://togogenome.org/gene/1821621:A8C75_RS13805 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZX1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS06035 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX31 ^@ Subunit ^@ Homotetramer. http://togogenome.org/gene/1821621:A8C75_RS22480 ^@ http://purl.uniprot.org/uniprot/A0A1A9F546 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CysZ family.|||Cell inner membrane|||High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway. http://togogenome.org/gene/1821621:A8C75_RS02755 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUC4 ^@ Similarity ^@ Belongs to the radical SAM superfamily. KamA family. http://togogenome.org/gene/1821621:A8C75_RS21190 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5Y6 ^@ Similarity ^@ Belongs to the allantoicase family. http://togogenome.org/gene/1821621:A8C75_RS22395 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3Q5 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/1821621:A8C75_RS06245 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWX5 ^@ Similarity ^@ Belongs to the GHMP kinase family. Mevalonate kinase subfamily. http://togogenome.org/gene/1821621:A8C75_RS04345 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVF9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.|||Cytoplasm|||In the C-terminal section; belongs to the DAO family.|||In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family. http://togogenome.org/gene/1821621:A8C75_RS14370 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1A3 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1821621:A8C75_RS07675 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXX2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Maintains high levels of reduced glutathione. http://togogenome.org/gene/1821621:A8C75_RS18695 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2T6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0014 family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS21750 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4D6 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1821621:A8C75_RS00460 ^@ http://purl.uniprot.org/uniprot/A0A1A9ESB6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS09205 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYD2 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/1821621:A8C75_RS20805 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3C1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS06330 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW57 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/1821621:A8C75_RS05280 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVN9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS00845 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUD0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS01140 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU68 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PhyH family. EctD subfamily.|||Homodimer.|||Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine. http://togogenome.org/gene/1821621:A8C75_RS09245 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYC1 ^@ Similarity ^@ Belongs to the PrpF family. http://togogenome.org/gene/1821621:A8C75_RS22605 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4I9 ^@ Similarity ^@ Belongs to the IucA/IucC family. http://togogenome.org/gene/1821621:A8C75_RS15350 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1H1 ^@ Similarity ^@ Belongs to the sodium:galactoside symporter (TC 2.A.2) family. http://togogenome.org/gene/1821621:A8C75_RS01855 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUT8 ^@ Function|||Similarity ^@ Belongs to the nucleoside phosphorylase PpnP family.|||Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. http://togogenome.org/gene/1821621:A8C75_RS06270 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW44 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.|||Cell membrane|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine. http://togogenome.org/gene/1821621:A8C75_RS04515 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVI2 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PdxA family.|||Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).|||Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).|||Cytoplasm|||Homodimer.|||The active site is located at the dimer interface. http://togogenome.org/gene/1821621:A8C75_RS04835 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVF4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS16700 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0S2 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1821621:A8C75_RS14130 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZI5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS07945 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWY1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS04755 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWE2 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily.|||Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. http://togogenome.org/gene/1821621:A8C75_RS13750 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZW1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS08040 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX97 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrF family.|||Binds 1 [2Fe-2S] cluster.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway. http://togogenome.org/gene/1821621:A8C75_RS22095 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4J3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS06015 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS17730 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2L7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS10620 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ07 ^@ Similarity ^@ Belongs to the GST superfamily. Zeta family. http://togogenome.org/gene/1821621:A8C75_RS10555 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZC4 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS07160 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWU9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/1821621:A8C75_RS10560 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYR0 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1821621:A8C75_RS12170 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ87 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/1821621:A8C75_RS06600 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWD5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/1821621:A8C75_RS01480 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUE0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/1821621:A8C75_RS04665 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVL3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS12820 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZD1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/1821621:A8C75_RS17535 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2Y1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/1821621:A8C75_RS19110 ^@ http://purl.uniprot.org/uniprot/A0A1A9F665 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/1821621:A8C75_RS12260 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZV7 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS22190 ^@ http://purl.uniprot.org/uniprot/A0A1A9F580 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/1821621:A8C75_RS12200 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ39 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS04720 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVM5 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/1821621:A8C75_RS01370 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUC2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/1821621:A8C75_RS03070 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUI7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS22425 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4Q8 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/1821621:A8C75_RS10915 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS06655 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVL1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS04160 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVQ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Cell inner membrane|||FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS17885 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1Q4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS17950 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2Q6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptF/LptG family.|||Cell inner membrane|||Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).|||Membrane|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. http://togogenome.org/gene/1821621:A8C75_RS03905 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV80 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS12290 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZA5 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/1821621:A8C75_RS21415 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4Y7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1821621:A8C75_RS08855 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXW6 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system. http://togogenome.org/gene/1821621:A8C75_RS05710 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVX4 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1821621:A8C75_RS04885 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUP7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the Cyclase 1 superfamily. KynB family.|||Binds 2 zinc ions per subunit.|||Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS02450 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUY3 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/1821621:A8C75_RS10030 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY13 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS18935 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3M7 ^@ Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily. http://togogenome.org/gene/1821621:A8C75_RS03900 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVN2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Heterodimer of an alpha and a beta chain.|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/1821621:A8C75_RS21070 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4A3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS16260 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0K1 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/1821621:A8C75_RS18245 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2Y2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS13155 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0Q0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS21715 ^@ http://purl.uniprot.org/uniprot/A0A1A9F533 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1821621:A8C75_RS07525 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW26 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/1821621:A8C75_RS04890 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVG6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the kynureninase family.|||Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS18320 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1M3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS00190 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETP7 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/1821621:A8C75_RS21275 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3F0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS02880 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVF6 ^@ Activity Regulation|||Caution|||Domain|||Function|||Similarity ^@ Belongs to the GlnD family.|||Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.|||Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity. http://togogenome.org/gene/1821621:A8C75_RS13550 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0G7 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/1821621:A8C75_RS04320 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVT3 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/1821621:A8C75_RS12145 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ29 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS20370 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2R6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS14985 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0X7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS03450 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVT1 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS11280 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZT2 ^@ Function|||Subunit ^@ Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS03965 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU91 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane|||Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. http://togogenome.org/gene/1821621:A8C75_RS00725 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS03295 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETY0 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS03625 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV69 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the tryptophan 2,3-dioxygenase family.|||Binds 1 heme group per subunit.|||Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS00925 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETH3 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS02595 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUD4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. MrdA subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall.|||Cell inner membrane http://togogenome.org/gene/1821621:A8C75_RS03020 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUH0 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1821621:A8C75_RS03970 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS01475 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU46 ^@ Similarity ^@ Belongs to the prokaryotic GSH synthase family. http://togogenome.org/gene/1821621:A8C75_RS22320 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4E1 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS17910 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2E0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS07165 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXP1 ^@ Similarity ^@ Belongs to the MQO family. http://togogenome.org/gene/1821621:A8C75_RS14395 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1D6 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1821621:A8C75_RS16080 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1S6 ^@ Cofactor ^@ Can also use Mn(2+) ion. http://togogenome.org/gene/1821621:A8C75_RS09160 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS17360 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2V4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Periplasm http://togogenome.org/gene/1821621:A8C75_RS19185 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3S5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/1821621:A8C75_RS16855 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1J8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS21585 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4N5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS00995 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU51 ^@ Function|||Similarity|||Subunit ^@ APS kinase catalyzes the synthesis of activated sulfate.|||Belongs to the APS kinase family.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.|||Catalyzes the synthesis of activated sulfate.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||In the C-terminal section; belongs to the APS kinase family.|||In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.|||With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/1821621:A8C75_RS06050 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW06 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Catalyzes the reversible hydration of fumarate to (S)-malate.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS06780 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWH3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/1821621:A8C75_RS21310 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3V5 ^@ Function|||Similarity ^@ Belongs to the BCKDHA family.|||The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/1821621:A8C75_RS06235 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX68 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IPP isomerase type 2 family.|||Cytoplasm|||Homooctamer. Dimer of tetramers.|||Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS17800 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2C1 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/1821621:A8C75_RS15175 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0M5 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/1821621:A8C75_RS02935 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUX1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/1821621:A8C75_RS02510 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUJ1 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/1821621:A8C75_RS12005 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ54 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1821621:A8C75_RS09330 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYV4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1821621:A8C75_RS01220 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5B7 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1821621:A8C75_RS18010 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2G2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS07995 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWB1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS05490 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW04 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS12830 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ97 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/1821621:A8C75_RS22705 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4V6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS10630 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZH2 ^@ Similarity ^@ Belongs to the homogentisate dioxygenase family. http://togogenome.org/gene/1821621:A8C75_RS13705 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0X3 ^@ Function ^@ Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin. http://togogenome.org/gene/1821621:A8C75_RS00105 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETP0 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/1821621:A8C75_RS12475 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ99 ^@ Similarity ^@ Belongs to the hyi family. http://togogenome.org/gene/1821621:A8C75_RS03015 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUH8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoS subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. http://togogenome.org/gene/1821621:A8C75_RS14300 ^@ http://purl.uniprot.org/uniprot/A0A1A9F045 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS08170 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX62 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase D family.|||Cytoplasm|||Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides. http://togogenome.org/gene/1821621:A8C75_RS00700 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETY5 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/1821621:A8C75_RS14060 ^@ http://purl.uniprot.org/uniprot/A0A1A9F067 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1821621:A8C75_RS14265 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0Y3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. http://togogenome.org/gene/1821621:A8C75_RS14955 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0G0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS09175 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXL8 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/1821621:A8C75_RS05845 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW73 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS15375 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1X3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS18420 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3D9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M20A family. DapE subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS14410 ^@ http://purl.uniprot.org/uniprot/A0A1A9F024 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS21280 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3H2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS00855 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS01640 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU75 ^@ Similarity|||Subunit ^@ Belongs to the complex I 75 kDa subunit family.|||Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex. http://togogenome.org/gene/1821621:A8C75_RS17095 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1H3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS12345 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0A5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS03915 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU81 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS22695 ^@ http://purl.uniprot.org/uniprot/A0A1A9F543 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1821621:A8C75_RS00800 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETA9 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1821621:A8C75_RS13850 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZW2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS02775 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVC8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/1821621:A8C75_RS14670 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1I5 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1821621:A8C75_RS14690 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0D0 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate. http://togogenome.org/gene/1821621:A8C75_RS15150 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0R5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TmcA family.|||Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||nucleolus http://togogenome.org/gene/1821621:A8C75_RS21355 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4J4 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1821621:A8C75_RS02335 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV35 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1821621:A8C75_RS07485 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWQ3 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1821621:A8C75_RS06140 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5I9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase T family.|||Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.|||Homodimer.|||Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. http://togogenome.org/gene/1821621:A8C75_RS09535 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY81 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS07795 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXC8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Pal lipoprotein family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/1821621:A8C75_RS19235 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2R7 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1821621:A8C75_RS22170 ^@ http://purl.uniprot.org/uniprot/A0A1A9F412 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS20475 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4H7 ^@ Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family. http://togogenome.org/gene/1821621:A8C75_RS09385 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYW4 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/1821621:A8C75_RS07565 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXV1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/1821621:A8C75_RS11425 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4U9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/1821621:A8C75_RS01765 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET25 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/1821621:A8C75_RS13445 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0V5 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/1821621:A8C75_RS08110 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWD3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS05890 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX02 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/1821621:A8C75_RS03105 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVA3 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/1821621:A8C75_RS12000 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS19390 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2U6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS07395 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXD3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS09125 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYA3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS04370 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVC5 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/1821621:A8C75_RS13525 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZL3 ^@ Similarity|||Subunit ^@ Belongs to the glutaminase family.|||Homotetramer. http://togogenome.org/gene/1821621:A8C75_RS10695 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXN4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS22370 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5B0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS20245 ^@ http://purl.uniprot.org/uniprot/A0A1A9F401 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/1821621:A8C75_RS13255 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0B7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the type IA topoisomerase family.|||Binds two Mg(2+) per subunit.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/1821621:A8C75_RS17980 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS13490 ^@ http://purl.uniprot.org/uniprot/A0A1A9F058 ^@ PTM ^@ The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/1821621:A8C75_RS10905 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZM1 ^@ Similarity ^@ Belongs to the FrmR/RcnR family. http://togogenome.org/gene/1821621:A8C75_RS00675 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU92 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase family.|||Belongs to the rubredoxin family. http://togogenome.org/gene/1821621:A8C75_RS01320 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUB1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxL/LpxM/LpxP family.|||Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).|||Cell inner membrane http://togogenome.org/gene/1821621:A8C75_RS12815 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYS3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS00525 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS04760 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVT9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS04550 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWA0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/1821621:A8C75_RS00875 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU19 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/1821621:A8C75_RS17115 ^@ http://purl.uniprot.org/uniprot/A0A1A9F204 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/1821621:A8C75_RS04905 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW43 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1821621:A8C75_RS06910 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWL4 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1821621:A8C75_RS17425 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2I6 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/1821621:A8C75_RS22280 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3N5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS17330 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2R4 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/1821621:A8C75_RS05240 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVS8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. FtsI subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.|||Cell inner membrane http://togogenome.org/gene/1821621:A8C75_RS16485 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5Z5 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1821621:A8C75_RS01980 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUN0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS02260 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS05790 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWN8 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system. http://togogenome.org/gene/1821621:A8C75_RS05005 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVI6 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS07170 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVV4 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/1821621:A8C75_RS10820 ^@ http://purl.uniprot.org/uniprot/A0A1A9F628 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS22385 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4F1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbA subfamily.|||Periplasm http://togogenome.org/gene/1821621:A8C75_RS02120 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUP4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS05385 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUY4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/1821621:A8C75_RS04685 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVC0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/1821621:A8C75_RS18545 ^@ http://purl.uniprot.org/uniprot/A0A1A9F331 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Binds 1 Fe cation per subunit.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/1821621:A8C75_RS17380 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1L6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS09670 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ12 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/1821621:A8C75_RS21855 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4T5 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1821621:A8C75_RS13350 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0Q7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/1821621:A8C75_RS21465 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3Y4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1821621:A8C75_RS01510 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETT5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS14845 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0A2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS02630 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5D7 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/1821621:A8C75_RS07125 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWJ3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.|||Belongs to the helicase family. UvrD subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.|||The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.|||The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC. http://togogenome.org/gene/1821621:A8C75_RS10715 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ41 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS15145 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1B6 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1821621:A8C75_RS08210 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY87 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/1821621:A8C75_RS10445 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYP2 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/1821621:A8C75_RS09830 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYN2 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/1821621:A8C75_RS00345 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU25 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/1821621:A8C75_RS07750 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS04950 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVH7 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1821621:A8C75_RS09725 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY36 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS16805 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0T9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1821621:A8C75_RS00685 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS16115 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5F5 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/1821621:A8C75_RS20175 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3V3 ^@ Function|||Similarity ^@ Belongs to the TenA family.|||Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP). http://togogenome.org/gene/1821621:A8C75_RS07220 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXQ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 1 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/1821621:A8C75_RS13080 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZY9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfur carrier protein TusA family.|||Cytoplasm|||Sulfur carrier protein which probably makes part of a sulfur-relay system. http://togogenome.org/gene/1821621:A8C75_RS00770 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS03045 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUY8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS10335 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ82 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/1821621:A8C75_RS07505 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX74 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/1821621:A8C75_RS14330 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0W9 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/1821621:A8C75_RS14860 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1J4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/1821621:A8C75_RS21270 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3K3 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/1821621:A8C75_RS20130 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3K9 ^@ Similarity ^@ Belongs to the DSD1 family. http://togogenome.org/gene/1821621:A8C75_RS21325 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3L2 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1821621:A8C75_RS16265 ^@ http://purl.uniprot.org/uniprot/A0A1A9F136 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1821621:A8C75_RS16720 ^@ http://purl.uniprot.org/uniprot/A0A1A9F239 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS02360 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV59 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS12625 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZG5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscS (TC 1.A.23) family.|||Cell inner membrane|||Homoheptamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions. http://togogenome.org/gene/1821621:A8C75_RS05405 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4W3 ^@ Cofactor ^@ Binds 2 Mg(2+) ions per monomer. http://togogenome.org/gene/1821621:A8C75_RS05105 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVL0 ^@ Similarity ^@ Belongs to the elongation factor P family. http://togogenome.org/gene/1821621:A8C75_RS21425 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3N2 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1821621:A8C75_RS07670 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXI6 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/1821621:A8C75_RS19000 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2G6 ^@ Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily. http://togogenome.org/gene/1821621:A8C75_RS00405 ^@ http://purl.uniprot.org/uniprot/A0A1A9ESA4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoH subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. http://togogenome.org/gene/1821621:A8C75_RS18130 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2I0 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1821621:A8C75_RS17185 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2S3 ^@ Function|||Similarity ^@ Belongs to the Dus family. DusB subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/1821621:A8C75_RS03630 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS03690 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVT7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS18975 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2Y8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS05670 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW09 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS06935 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWR5 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1821621:A8C75_RS05415 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWR3 ^@ Function|||Similarity ^@ Belongs to the peptidase M16 family.|||Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin. http://togogenome.org/gene/1821621:A8C75_RS03745 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS09860 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX81 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1821621:A8C75_RS09710 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYA7 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/1821621:A8C75_RS20920 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3N3 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF1 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS21340 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4E9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1821621:A8C75_RS17310 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1L8 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/1821621:A8C75_RS07065 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWM2 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS21360 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3W4 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1821621:A8C75_RS22740 ^@ http://purl.uniprot.org/uniprot/A0A1A9F688 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/1821621:A8C75_RS11680 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS01100 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS15780 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1N4 ^@ Function|||Similarity ^@ Belongs to the PhnJ family.|||Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. http://togogenome.org/gene/1821621:A8C75_RS04925 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVW9 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS16050 ^@ http://purl.uniprot.org/uniprot/A0A1A9F104 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/1821621:A8C75_RS07920 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS04380 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW65 ^@ Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 2 family. http://togogenome.org/gene/1821621:A8C75_RS03835 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS20375 ^@ http://purl.uniprot.org/uniprot/A0A1A9F660 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS01615 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETQ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1821621:A8C75_RS07465 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWZ8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS20995 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3F2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamD family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/1821621:A8C75_RS08025 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY39 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrC family.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/1821621:A8C75_RS07475 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS21035 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3Q0 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1821621:A8C75_RS02575 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVA2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS15295 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1G1 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/1821621:A8C75_RS00690 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET88 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1821621:A8C75_RS22240 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5P7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1821621:A8C75_RS17135 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2R1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS19650 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2M1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS07850 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXE2 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS12590 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZB9 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1821621:A8C75_RS22300 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4X4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS05000 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUR8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS17495 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1P8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/1821621:A8C75_RS14465 ^@ http://purl.uniprot.org/uniprot/A0A1A9F033 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Gfo/Idh/MocA family.|||Homotetramer.|||Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose). http://togogenome.org/gene/1821621:A8C75_RS12325 ^@ http://purl.uniprot.org/uniprot/A0A1A9F077 ^@ Function|||Similarity ^@ Belongs to the mannonate dehydratase family.|||Catalyzes the dehydration of D-mannonate. http://togogenome.org/gene/1821621:A8C75_RS17120 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5H6 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1821621:A8C75_RS07240 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWS7 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/1821621:A8C75_RS03975 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS06195 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWD0 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/1821621:A8C75_RS07825 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX08 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/1821621:A8C75_RS09240 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXP6 ^@ Similarity ^@ Belongs to the aconitase/IPM isomerase family. http://togogenome.org/gene/1821621:A8C75_RS10825 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZH0 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1821621:A8C75_RS01810 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUJ9 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1821621:A8C75_RS09355 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXR6 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/1821621:A8C75_RS20070 ^@ http://purl.uniprot.org/uniprot/A0A1A9F453 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1821621:A8C75_RS12925 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYU7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS03515 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV15 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1821621:A8C75_RS08815 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS07840 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXL6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1821621:A8C75_RS22475 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4R1 ^@ Function ^@ Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals. http://togogenome.org/gene/1821621:A8C75_RS00400 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU34 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell inner membrane|||Forms a membrane-associated complex with FtsE.|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/1821621:A8C75_RS22810 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4X6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/1821621:A8C75_RS09930 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXW7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS03405 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUP1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS06370 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWF5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrB/RnfD family.|||Cell inner membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1821621:A8C75_RS01630 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUF1 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/1821621:A8C75_RS10550 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ08 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS08870 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYL9 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1821621:A8C75_RS02185 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUS9 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1821621:A8C75_RS01645 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUH1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/1821621:A8C75_RS19680 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2Z7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS06785 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWD6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/1821621:A8C75_RS17880 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1W9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS15715 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0V1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP H family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS17125 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2D4 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1821621:A8C75_RS11295 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYN6 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/1821621:A8C75_RS10590 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS16475 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2F0 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1821621:A8C75_RS07915 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5L0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS02885 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUW2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1821621:A8C75_RS00470 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET49 ^@ Similarity|||Subunit ^@ Belongs to the transketolase family.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS08475 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS06240 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWK5 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. HMG-CoA synthase family. http://togogenome.org/gene/1821621:A8C75_RS15000 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1Q3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. http://togogenome.org/gene/1821621:A8C75_RS21490 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3L1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1821621:A8C75_RS08805 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS01165 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUI6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS09300 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYD0 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the ferredoxin--NADP reductase type 2 family.|||Binds 1 FAD per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS21335 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3I2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/1821621:A8C75_RS14875 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0V6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS02350 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUG6 ^@ Similarity ^@ Belongs to the UPF0125 (RnfH) family. http://togogenome.org/gene/1821621:A8C75_RS09565 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4M3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS19090 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5V4 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/1821621:A8C75_RS05085 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWA6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 3 lipoyl cofactors covalently.|||Forms a 24-polypeptide structural core with octahedral symmetry.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/1821621:A8C75_RS05720 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW19 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/1821621:A8C75_RS01335 ^@ http://purl.uniprot.org/uniprot/A0A1A9EST9 ^@ Function|||Similarity ^@ Belongs to the frataxin family.|||Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. http://togogenome.org/gene/1821621:A8C75_RS04170 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS07150 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX20 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscS (TC 1.A.23) family.|||Cell inner membrane|||Homoheptamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS16090 ^@ http://purl.uniprot.org/uniprot/A0A1A9F281 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS15710 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0P1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP I family.|||Cell inner membrane http://togogenome.org/gene/1821621:A8C75_RS18480 ^@ http://purl.uniprot.org/uniprot/A0A1A9F277 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family. GreB subfamily.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length. http://togogenome.org/gene/1821621:A8C75_RS04035 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1821621:A8C75_RS17060 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1Z2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS01200 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS22375 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4P2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS19175 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3E7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1821621:A8C75_RS11800 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYW6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS22325 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5D6 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/1821621:A8C75_RS10070 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY90 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/1821621:A8C75_RS17995 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1X6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS07495 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXF3 ^@ Cofactor|||Function|||Subcellular Location Annotation|||Subunit ^@ Cell inner membrane|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/1821621:A8C75_RS12100 ^@ http://purl.uniprot.org/uniprot/A0A1A9F040 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/1821621:A8C75_RS21705 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4Q4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UbiD family.|||Binds 1 prenylated FMN (prenyl-FMN) per subunit.|||Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.|||Cell membrane|||Homohexamer. http://togogenome.org/gene/1821621:A8C75_RS13690 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZP2 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/1821621:A8C75_RS18355 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2M6 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1821621:A8C75_RS00640 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETB9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1821621:A8C75_RS04895 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS05255 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW27 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS11870 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZN0 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 1 family. http://togogenome.org/gene/1821621:A8C75_RS14230 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1A7 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/1821621:A8C75_RS22360 ^@ http://purl.uniprot.org/uniprot/A0A1A9F400 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1821621:A8C75_RS22415 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4Z4 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1821621:A8C75_RS12725 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5A0 ^@ Cofactor|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Binds 1 [4Fe-4S] cluster per subunit. http://togogenome.org/gene/1821621:A8C75_RS05910 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW83 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/1821621:A8C75_RS12305 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ47 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS05595 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWV7 ^@ Similarity ^@ Belongs to the SlyX family. http://togogenome.org/gene/1821621:A8C75_RS04440 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVM1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS04240 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW61 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sigma-70 factor family. FliA subfamily.|||Cytoplasm|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes. http://togogenome.org/gene/1821621:A8C75_RS10870 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYC9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS01770 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETV5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS06115 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LysR transcriptional regulatory family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS19575 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2Q9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS15995 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWH6 ^@ Similarity ^@ Belongs to the transposase 8 family. http://togogenome.org/gene/1821621:A8C75_RS22775 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5L3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. http://togogenome.org/gene/1821621:A8C75_RS15205 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0S5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the aldolase class II family. MtnB subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). http://togogenome.org/gene/1821621:A8C75_RS13395 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ36 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/1821621:A8C75_RS21385 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3J2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/1821621:A8C75_RS01400 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETR3 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/1821621:A8C75_RS04215 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVR4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1821621:A8C75_RS13295 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0E0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS05800 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWZ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptC family.|||Cell inner membrane|||Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.|||Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. http://togogenome.org/gene/1821621:A8C75_RS20990 ^@ http://purl.uniprot.org/uniprot/A0A1A9F585 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1821621:A8C75_RS16715 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1B0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS20565 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3S9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein PotD/PotF family.|||Periplasm|||Required for the activity of the bacterial periplasmic transport system of putrescine. http://togogenome.org/gene/1821621:A8C75_RS12165 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZR5 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/1821621:A8C75_RS17600 ^@ http://purl.uniprot.org/uniprot/A0A1A9F188 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS13455 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ51 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS04500 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW89 ^@ Function|||Similarity ^@ Belongs to the Ap4A hydrolase family.|||Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP. http://togogenome.org/gene/1821621:A8C75_RS14215 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0I9 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/1821621:A8C75_RS18370 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3C9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PqiA family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS05570 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWG7 ^@ Similarity ^@ Belongs to the KAE1 / TsaD family. TsaB subfamily. http://togogenome.org/gene/1821621:A8C75_RS04915 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWG9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1821621:A8C75_RS02980 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV57 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1821621:A8C75_RS21725 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3S8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.|||Binds 1 Mn(2+) ion per subunit.|||Cytoplasm|||Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS20710 ^@ http://purl.uniprot.org/uniprot/A0A1A9F380 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS04700 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWD2 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. http://togogenome.org/gene/1821621:A8C75_RS22470 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5D0 ^@ Function ^@ This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited. http://togogenome.org/gene/1821621:A8C75_RS09990 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS19370 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3F6 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/1821621:A8C75_RS22450 ^@ http://purl.uniprot.org/uniprot/A0A1A9F458 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/1821621:A8C75_RS11460 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYK3 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/1821621:A8C75_RS22430 ^@ http://purl.uniprot.org/uniprot/A0A1A9F537 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PstS family.|||Involved in the system for phosphate transport across the cytoplasmic membrane.|||Periplasm|||Secreted http://togogenome.org/gene/1821621:A8C75_RS01420 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU39 ^@ Function|||Similarity ^@ Belongs to the HPPK family.|||Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway. http://togogenome.org/gene/1821621:A8C75_RS16255 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2B4 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/1821621:A8C75_RS23895 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVB4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZipA family.|||Cell inner membrane|||Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.|||Interacts with FtsZ via their C-terminal domains. http://togogenome.org/gene/1821621:A8C75_RS18945 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2F6 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS06185 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWJ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HscB family.|||Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.|||Interacts with HscA and stimulates its ATPase activity. http://togogenome.org/gene/1821621:A8C75_RS05990 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWP1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.|||Binds 2 manganese ions per subunit.|||Splits dipeptides with a prolyl residue in the C-terminal position. http://togogenome.org/gene/1821621:A8C75_RS19125 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2I4 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/1821621:A8C75_RS01675 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETW2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1821621:A8C75_RS20940 ^@ http://purl.uniprot.org/uniprot/A0A1A9F392 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS14205 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0W4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1821621:A8C75_RS03865 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU72 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1821621:A8C75_RS08500 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWK9 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/1821621:A8C75_RS14620 ^@ http://purl.uniprot.org/uniprot/A0A1A9F063 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/1821621:A8C75_RS06775 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVN1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/1821621:A8C75_RS22220 ^@ http://purl.uniprot.org/uniprot/A0A1A9F416 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1821621:A8C75_RS13765 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0A6 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1821621:A8C75_RS09810 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS00520 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpxP/Spy family.|||Periplasm http://togogenome.org/gene/1821621:A8C75_RS10875 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYH5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS01040 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the etk/wzc family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS15050 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1R3 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1821621:A8C75_RS10115 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYS7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS12510 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYL2 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/1821621:A8C75_RS14630 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0C0 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1821621:A8C75_RS21930 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3X1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS05295 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVU1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/1821621:A8C75_RS14350 ^@ http://purl.uniprot.org/uniprot/A0A1A9F054 ^@ Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. http://togogenome.org/gene/1821621:A8C75_RS21570 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4J2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/1821621:A8C75_RS02480 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUB4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/1821621:A8C75_RS01365 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU29 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1821621:A8C75_RS22735 ^@ http://purl.uniprot.org/uniprot/A0A1A9F466 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/1821621:A8C75_RS20280 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3W9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS17900 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2P7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS21805 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4S5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS03490 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUV5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OadG family.|||Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.|||Cell membrane|||Heterotrimer of an alpha, a beta and a gamma subunit.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS22180 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3X2 ^@ Function|||Similarity ^@ Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.|||Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/1821621:A8C75_RS19010 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2E2 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/1821621:A8C75_RS14590 ^@ http://purl.uniprot.org/uniprot/A0A1A9F119 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1821621:A8C75_RS05310 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW36 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/1821621:A8C75_RS14200 ^@ http://purl.uniprot.org/uniprot/A0A1A9F039 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1821621:A8C75_RS06945 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVR1 ^@ Similarity ^@ Belongs to the HIBADH-related family. http://togogenome.org/gene/1821621:A8C75_RS12780 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZE6 ^@ Caution|||Function|||Similarity ^@ Belongs to the Dus family. DusC subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS05050 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS05530 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW79 ^@ Similarity ^@ Belongs to the UPF0502 family. http://togogenome.org/gene/1821621:A8C75_RS07085 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX85 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS18875 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3L9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS07950 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX42 ^@ Function|||Subunit ^@ DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease. http://togogenome.org/gene/1821621:A8C75_RS05820 ^@ http://purl.uniprot.org/uniprot/A0A1A9EW37 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD). http://togogenome.org/gene/1821621:A8C75_RS07490 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWW8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome b560 family.|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/1821621:A8C75_RS22250 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4M8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/1821621:A8C75_RS21445 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4V8 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||Methylated by PrmB.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/1821621:A8C75_RS12070 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYC2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS12130 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ18 ^@ Function|||Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.|||DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes. http://togogenome.org/gene/1821621:A8C75_RS09790 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ33 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1821621:A8C75_RS14080 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZZ9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/1821621:A8C75_RS02140 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUC8 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/1821621:A8C75_RS10655 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZ31 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1821621:A8C75_RS04480 ^@ http://purl.uniprot.org/uniprot/A0A1A9EV87 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/1821621:A8C75_RS21430 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3I0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1821621:A8C75_RS10545 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYB9 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. http://togogenome.org/gene/1821621:A8C75_RS01705 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUU1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS21365 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4X7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1821621:A8C75_RS10110 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYH6 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1821621:A8C75_RS12845 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0G6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS11655 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZH1 ^@ Similarity ^@ Belongs to the HsdR family. http://togogenome.org/gene/1821621:A8C75_RS10510 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYQ0 ^@ Similarity ^@ Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. http://togogenome.org/gene/1821621:A8C75_RS05840 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWP8 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/1821621:A8C75_RS15895 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1D5 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/1821621:A8C75_RS11820 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS12905 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZV9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/1821621:A8C75_RS00340 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETF1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS18175 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2U3 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/1821621:A8C75_RS20935 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3E2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the COX11/CtaG family.|||Cell inner membrane|||Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I. http://togogenome.org/gene/1821621:A8C75_RS00745 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETE0 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/1821621:A8C75_RS14695 ^@ http://purl.uniprot.org/uniprot/A0A1A9F151 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS20150 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2M0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1821621:A8C75_RS07755 ^@ http://purl.uniprot.org/uniprot/A0A1A9EY01 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/1821621:A8C75_RS21095 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4T0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1821621:A8C75_RS20600 ^@ http://purl.uniprot.org/uniprot/A0A1A9F361 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS17435 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2W3 ^@ Similarity ^@ Belongs to the YfgM family. http://togogenome.org/gene/1821621:A8C75_RS21435 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3K2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/1821621:A8C75_RS02470 ^@ http://purl.uniprot.org/uniprot/A0A1A9EU83 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/1821621:A8C75_RS22800 ^@ http://purl.uniprot.org/uniprot/A0A1A9F562 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS01355 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUA8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/1821621:A8C75_RS21230 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4R8 ^@ Similarity ^@ Belongs to the hyi family. http://togogenome.org/gene/1821621:A8C75_RS20030 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3V7 ^@ Similarity ^@ Belongs to the UPF0231 family. http://togogenome.org/gene/1821621:A8C75_RS03790 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVV6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS17990 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1S4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/1821621:A8C75_RS17820 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1C9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS22085 ^@ http://purl.uniprot.org/uniprot/A0A1A9F5Z6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS20440 ^@ http://purl.uniprot.org/uniprot/A0A1A9F336 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS02080 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUQ2 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/1821621:A8C75_RS10450 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYY2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS20260 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2P0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1821621:A8C75_RS00050 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETW9 ^@ PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS21555 ^@ http://purl.uniprot.org/uniprot/A0A1A9F3Q3 ^@ Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.|||Belongs to the biotin--protein ligase family. http://togogenome.org/gene/1821621:A8C75_RS03270 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVD1 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/1821621:A8C75_RS05175 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVR8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome b family.|||Binds 2 heme groups non-covalently.|||Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.|||Membrane|||The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein. http://togogenome.org/gene/1821621:A8C75_RS18765 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1U9 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS17660 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1L7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS11205 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYS8 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/1821621:A8C75_RS17525 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2K6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueG family.|||Binds 2 [4Fe-4S] clusters per monomer.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1821621:A8C75_RS21440 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4H4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1821621:A8C75_RS02930 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVG9 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/1821621:A8C75_RS00580 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET69 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiK family.|||Cytoplasm|||Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both. http://togogenome.org/gene/1821621:A8C75_RS07780 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX19 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbD/TolR family.|||Cell inner membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/1821621:A8C75_RS11560 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYS5 ^@ Function ^@ E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/1821621:A8C75_RS20930 ^@ http://purl.uniprot.org/uniprot/A0A1A9F306 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS05245 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWA4 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1821621:A8C75_RS13895 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZD9 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1821621:A8C75_RS16935 ^@ http://purl.uniprot.org/uniprot/A0A1A9F609 ^@ Similarity ^@ Belongs to the UPF0246 family. http://togogenome.org/gene/1821621:A8C75_RS21345 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4T7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1821621:A8C75_RS20455 ^@ http://purl.uniprot.org/uniprot/A0A1A9F6K1 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/1821621:A8C75_RS09640 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYI6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS14250 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZZ4 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/1821621:A8C75_RS20165 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2Y9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.|||Homodimer. http://togogenome.org/gene/1821621:A8C75_RS11785 ^@ http://purl.uniprot.org/uniprot/A0A1A9F006 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1821621:A8C75_RS11775 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZJ4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IlvD/Edd family.|||Binds 1 [4Fe-4S] cluster.|||Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate. http://togogenome.org/gene/1821621:A8C75_RS12455 ^@ http://purl.uniprot.org/uniprot/A0A1A9EYJ1 ^@ Similarity ^@ Belongs to the four-carbon acid sugar kinase family. http://togogenome.org/gene/1821621:A8C75_RS01710 ^@ http://purl.uniprot.org/uniprot/A0A1A9ET14 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1821621:A8C75_RS13440 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZW0 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS07420 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXT8 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/1821621:A8C75_RS13420 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0R9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SNF2/RAD54 helicase family. RapA subfamily.|||Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.|||Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair. http://togogenome.org/gene/1821621:A8C75_RS02690 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/1821621:A8C75_RS18845 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2B1 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS14775 ^@ http://purl.uniprot.org/uniprot/A0A1A9F0K2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1821621:A8C75_RS16800 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2K0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease beta subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1821621:A8C75_RS12800 ^@ http://purl.uniprot.org/uniprot/A0A1A9F031 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1821621:A8C75_RS09285 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXN8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS08010 ^@ http://purl.uniprot.org/uniprot/A0A1A9EWZ3 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1821621:A8C75_RS04565 ^@ http://purl.uniprot.org/uniprot/A0A1A9EVI8 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/1821621:A8C75_RS04190 ^@ http://purl.uniprot.org/uniprot/A0A1A9EUC9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Cell inner membrane|||FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS02055 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETY8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/1821621:A8C75_RS07895 ^@ http://purl.uniprot.org/uniprot/A0A1A9EXM9 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/1821621:A8C75_RS00605 ^@ http://purl.uniprot.org/uniprot/A0A1A9ETN7 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/1821621:A8C75_RS22150 ^@ http://purl.uniprot.org/uniprot/A0A1A9F4Y2 ^@ Similarity ^@ Belongs to the SfsA family. http://togogenome.org/gene/1821621:A8C75_RS10580 ^@ http://purl.uniprot.org/uniprot/A0A1A9EZG8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1821621:A8C75_RS16690 ^@ http://purl.uniprot.org/uniprot/A0A1A9F1G8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1821621:A8C75_RS18300 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2Z2 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/1821621:A8C75_RS08115 ^@ http://purl.uniprot.org/uniprot/A0A1A9EX59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1821621:A8C75_RS17275 ^@ http://purl.uniprot.org/uniprot/A0A1A9F2D6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mg(2+). Can also accept Mn(2+).