http://togogenome.org/gene/1796616:A4V09_RS19420 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDD7 ^@ Similarity ^@ Belongs to the CvfB family. http://togogenome.org/gene/1796616:A4V09_RS05095 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8K1 ^@ Similarity ^@ Belongs to the UPF0237 family. http://togogenome.org/gene/1796616:A4V09_RS10200 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB74 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1796616:A4V09_RS03350 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS02710 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHJ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS15790 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFV5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1796616:A4V09_RS11915 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9M5 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/1796616:A4V09_RS04735 ^@ http://purl.uniprot.org/uniprot/A0A1C7I849 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS14825 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEJ5 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/1796616:A4V09_RS03965 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8W0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/1796616:A4V09_RS15995 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDJ8 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/1796616:A4V09_RS17640 ^@ http://purl.uniprot.org/uniprot/A0A1C7IET3 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS19505 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDB8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS15495 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBH6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS15725 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF06 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1796616:A4V09_RS16225 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS17380 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICD8 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/1796616:A4V09_RS03985 ^@ http://purl.uniprot.org/uniprot/A0A1C7I818 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1796616:A4V09_RS22135 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEP9 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1796616:A4V09_RS24020 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS18030 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGZ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS05030 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFW0 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine. http://togogenome.org/gene/1796616:A4V09_RS03890 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5V8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS23265 ^@ http://purl.uniprot.org/uniprot/A0A1C7IL13 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the KduI family.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. http://togogenome.org/gene/1796616:A4V09_RS02255 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4V3 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS21275 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIP7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS21770 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEH8 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/1796616:A4V09_RS00190 ^@ http://purl.uniprot.org/uniprot/A0A1C7IK37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS18095 ^@ http://purl.uniprot.org/uniprot/A0A1C7IH01 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1796616:A4V09_RS06475 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6W0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/1796616:A4V09_RS09915 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBY4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS21585 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEF4 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. http://togogenome.org/gene/1796616:A4V09_RS01475 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4K8 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS02680 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5A9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/1796616:A4V09_RS02715 ^@ http://purl.uniprot.org/uniprot/A0A1C7I527 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS08565 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB97 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/1796616:A4V09_RS12295 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9U8 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine. http://togogenome.org/gene/1796616:A4V09_RS23055 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFE7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1796616:A4V09_RS20000 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDP8 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/1796616:A4V09_RS11255 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB60 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/1796616:A4V09_RS10285 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8V7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS04070 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5S3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS07025 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7B9 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/1796616:A4V09_RS19410 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGV4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-C family. DnaE subfamily.|||Cytoplasm|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase. http://togogenome.org/gene/1796616:A4V09_RS08275 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7Y2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS06300 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6Z0 ^@ Similarity ^@ Belongs to the EutP/PduV family. http://togogenome.org/gene/1796616:A4V09_RS21620 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGL7 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS05690 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8W3 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/1796616:A4V09_RS02720 ^@ http://purl.uniprot.org/uniprot/A0A1C7IJF7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS22355 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGK5 ^@ Function ^@ Catalyzes the synthesis of GMP from XMP. http://togogenome.org/gene/1796616:A4V09_RS14795 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS17270 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGC3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1796616:A4V09_RS10815 ^@ http://purl.uniprot.org/uniprot/A0A1C7I999 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1796616:A4V09_RS01975 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4M4 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/1796616:A4V09_RS12020 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS17440 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICE8 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/1796616:A4V09_RS09350 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICJ1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1796616:A4V09_RS03805 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5S0 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/1796616:A4V09_RS15485 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEW1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS17560 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICG9 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1796616:A4V09_RS10500 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICA5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family.|||Binds 1 zinc or iron ion per subunit.|||Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS18685 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1796616:A4V09_RS21460 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEL9 ^@ Function|||Similarity ^@ Belongs to the PduL family.|||Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. http://togogenome.org/gene/1796616:A4V09_RS11810 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9K8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1796616:A4V09_RS05500 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6J8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS10670 ^@ http://purl.uniprot.org/uniprot/A0A1C7I968 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS21945 ^@ http://purl.uniprot.org/uniprot/A0A1C7IJ14 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS00030 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5V3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS13550 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAH3 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/1796616:A4V09_RS03485 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5L3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS08290 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7X6 ^@ Similarity ^@ Belongs to the type A lantibiotic family. http://togogenome.org/gene/1796616:A4V09_RS16965 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC72 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by fructose 1,6-bisphosphate (FBP).|||Belongs to the LDH/MDH superfamily. LDH family.|||Catalyzes the conversion of lactate to pyruvate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS10675 ^@ http://purl.uniprot.org/uniprot/A0A1C7IJR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS12785 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA49 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS07835 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7M1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS08985 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8C8 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1796616:A4V09_RS04550 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8B1 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1796616:A4V09_RS14175 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB01 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1796616:A4V09_RS04075 ^@ http://purl.uniprot.org/uniprot/A0A1C7IKA4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS19735 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDI4 ^@ Similarity ^@ Belongs to the CpsD/CapB family. http://togogenome.org/gene/1796616:A4V09_RS03475 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7J2 ^@ Function ^@ Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function. http://togogenome.org/gene/1796616:A4V09_RS00270 ^@ http://purl.uniprot.org/uniprot/A0A1C7I450 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/1796616:A4V09_RS15800 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDP6 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1796616:A4V09_RS19495 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDL9 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1796616:A4V09_RS12455 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC20 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/1796616:A4V09_RS14955 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFF8 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1796616:A4V09_RS19150 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID91 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/1796616:A4V09_RS02355 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4U1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS04805 ^@ http://purl.uniprot.org/uniprot/A0A1C7I607 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).|||Belongs to the FGGY kinase family.|||Homotetramer and homodimer (in equilibrium).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/1796616:A4V09_RS20780 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE04 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS10505 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8Z4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS14535 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAY2 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/1796616:A4V09_RS08815 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS15750 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDN7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1796616:A4V09_RS07950 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9J1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS02020 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4Y4 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS08530 ^@ http://purl.uniprot.org/uniprot/A0A1C7I848 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the spermidine/spermine synthase family.|||Cell membrane http://togogenome.org/gene/1796616:A4V09_RS04270 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5S2 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/1796616:A4V09_RS17910 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG33 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/1796616:A4V09_RS06915 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7A5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS20810 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDY9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS05170 ^@ http://purl.uniprot.org/uniprot/A0A1C7I660 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/1796616:A4V09_RS15205 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID60 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/1796616:A4V09_RS23760 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFG0 ^@ Function|||Similarity ^@ Belongs to the IolE/MocC family.|||Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol). http://togogenome.org/gene/1796616:A4V09_RS04140 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9V0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/1796616:A4V09_RS10600 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS14140 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICM5 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/1796616:A4V09_RS13840 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICS2 ^@ Function|||Similarity ^@ Belongs to the ROK (NagC/XylR) family.|||Transcriptional repressor of xylose-utilizing enzymes. http://togogenome.org/gene/1796616:A4V09_RS05405 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9K4 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/1796616:A4V09_RS19740 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFC1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS12490 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9X8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS21310 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG30 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/1796616:A4V09_RS15840 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFW6 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/1796616:A4V09_RS05770 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6H0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/1796616:A4V09_RS03285 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5I1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS12255 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9T7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS09970 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBZ4 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/1796616:A4V09_RS02215 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHI3 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1796616:A4V09_RS19950 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDN8 ^@ Function|||Similarity ^@ Belongs to the ROK (NagC/XylR) family.|||Transcriptional repressor of xylose-utilizing enzymes. http://togogenome.org/gene/1796616:A4V09_RS15360 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBD9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/1796616:A4V09_RS21910 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEH1 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1796616:A4V09_RS08970 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICC2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS02630 ^@ http://purl.uniprot.org/uniprot/A0A1C7I598 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1796616:A4V09_RS02785 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7F5 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/1796616:A4V09_RS01985 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7T5 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/1796616:A4V09_RS06710 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS02295 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4T1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/1796616:A4V09_RS05940 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8I3 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/1796616:A4V09_RS06840 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9K5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS12720 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC74 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/1796616:A4V09_RS07820 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9S1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Homohexamer. Forms a ring that surrounds DNA.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS00415 ^@ http://purl.uniprot.org/uniprot/A0A1C7I721 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/1796616:A4V09_RS20490 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS20590 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIM5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS07960 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7Q9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/1796616:A4V09_RS17295 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEE6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS06995 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7D3 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/1796616:A4V09_RS15905 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDZ1 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/1796616:A4V09_RS03220 ^@ http://purl.uniprot.org/uniprot/A0A1C7I779 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/1796616:A4V09_RS11815 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG47 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1796616:A4V09_RS15460 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDK0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS10265 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8V4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS01385 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4M7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS04700 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5Y7 ^@ Similarity ^@ Belongs to the UPF0246 family. http://togogenome.org/gene/1796616:A4V09_RS03810 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9P2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1796616:A4V09_RS10660 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICD2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS22340 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF22 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS04750 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5Z7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1796616:A4V09_RS00400 ^@ http://purl.uniprot.org/uniprot/A0A1C7I3V6 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily. http://togogenome.org/gene/1796616:A4V09_RS11675 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9J0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS05465 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6G0 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/1796616:A4V09_RS21175 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGE5 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/1796616:A4V09_RS21750 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGI6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS03605 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5N3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/1796616:A4V09_RS13110 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEH4 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/1796616:A4V09_RS20360 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDR3 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS11680 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9L3 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. http://togogenome.org/gene/1796616:A4V09_RS18120 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICP1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/1796616:A4V09_RS12200 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID61 ^@ Similarity ^@ Belongs to the UPF0597 family. http://togogenome.org/gene/1796616:A4V09_RS16375 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBV3 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/1796616:A4V09_RS16865 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC52 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS15820 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDH9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/1796616:A4V09_RS06275 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS04065 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8Y0 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1796616:A4V09_RS03570 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8P5 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/1796616:A4V09_RS00520 ^@ http://purl.uniprot.org/uniprot/A0A1C7I742 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS17120 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC67 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS12805 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1796616:A4V09_RS16950 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE96 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/1796616:A4V09_RS16130 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE34 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/1796616:A4V09_RS14005 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEY8 ^@ Similarity ^@ Belongs to the hyi family. http://togogenome.org/gene/1796616:A4V09_RS23630 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFG2 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1796616:A4V09_RS22555 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEZ5 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1796616:A4V09_RS11745 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBF3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS19840 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS17915 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICJ8 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/1796616:A4V09_RS00450 ^@ http://purl.uniprot.org/uniprot/A0A1C7I439 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS12190 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9V2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS16100 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBS1 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1796616:A4V09_RS04215 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5Z5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS17095 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC97 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/1796616:A4V09_RS21600 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS22275 ^@ http://purl.uniprot.org/uniprot/A0A1C7IJ76 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. http://togogenome.org/gene/1796616:A4V09_RS21170 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGI7 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/1796616:A4V09_RS12710 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE98 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1796616:A4V09_RS03235 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5H4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/1796616:A4V09_RS22895 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ribonuclease N1/T1 family.|||Secreted http://togogenome.org/gene/1796616:A4V09_RS09145 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBK2 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/1796616:A4V09_RS15685 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFT6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1796616:A4V09_RS06985 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG58 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/1796616:A4V09_RS17940 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEQ8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/1796616:A4V09_RS16915 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDZ3 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/1796616:A4V09_RS17105 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEJ3 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/1796616:A4V09_RS16550 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBX8 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/1796616:A4V09_RS16435 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBW3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS17205 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE33 ^@ Function|||Similarity ^@ Belongs to the SpoVG family.|||Could be involved in septation. http://togogenome.org/gene/1796616:A4V09_RS20460 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG63 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS15560 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBF8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. http://togogenome.org/gene/1796616:A4V09_RS03955 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFW4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS16425 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE09 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/1796616:A4V09_RS10190 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8Y7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS14910 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBC9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1796616:A4V09_RS07410 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9A3 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1796616:A4V09_RS05265 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8E1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS16040 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBQ9 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS03845 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8U4 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/1796616:A4V09_RS01765 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6X2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS21825 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEL1 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1796616:A4V09_RS11235 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBF6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the energy-coupling factor EcfT family.|||Cell membrane|||Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).|||Membrane|||Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. http://togogenome.org/gene/1796616:A4V09_RS02490 ^@ http://purl.uniprot.org/uniprot/A0A1C7I547 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS02285 ^@ http://purl.uniprot.org/uniprot/A0A1C7I533 ^@ Function|||PTM|||Similarity|||Subunit ^@ Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.|||Belongs to the peptidase A25 family.|||Homotetramer.|||Initiates the rapid degradation of small, acid-soluble proteins during spore germination. http://togogenome.org/gene/1796616:A4V09_RS10965 ^@ http://purl.uniprot.org/uniprot/A0A1C7I974 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1796616:A4V09_RS12185 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9S9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS13495 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAG8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/1796616:A4V09_RS05710 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6G3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiN family.|||Cell membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/1796616:A4V09_RS24035 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHV4 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/1796616:A4V09_RS19930 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS09430 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAB3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS13240 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICG6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the selenophosphate synthase 1 family. Class I subfamily.|||Binds 1 Mg(2+) ion per monomer.|||Homodimer.|||Synthesizes selenophosphate from selenide and ATP. http://togogenome.org/gene/1796616:A4V09_RS10810 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB79 ^@ Similarity ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family. http://togogenome.org/gene/1796616:A4V09_RS16415 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE86 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS06015 ^@ http://purl.uniprot.org/uniprot/A0A1C7I929 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS16930 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC45 ^@ Cofactor ^@ Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/1796616:A4V09_RS21555 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS10275 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAQ2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/1796616:A4V09_RS03555 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5M0 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS02135 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6M3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/1796616:A4V09_RS00940 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4D4 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/1796616:A4V09_RS00220 ^@ http://purl.uniprot.org/uniprot/A0A1C7I3S5 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. http://togogenome.org/gene/1796616:A4V09_RS22370 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEW2 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS13565 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDV7 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/1796616:A4V09_RS12730 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS22950 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS20945 ^@ http://purl.uniprot.org/uniprot/A0A1C7III6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS08015 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7S1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS06910 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7C8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/1796616:A4V09_RS02065 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6T5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/1796616:A4V09_RS23135 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIX2 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/1796616:A4V09_RS09175 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAF6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1796616:A4V09_RS18070 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEI5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1796616:A4V09_RS15200 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBB5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CodY family.|||Cytoplasm|||DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor. http://togogenome.org/gene/1796616:A4V09_RS14855 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Nucleus http://togogenome.org/gene/1796616:A4V09_RS05130 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9G6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/1796616:A4V09_RS12100 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS10235 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8U7 ^@ Function|||Subunit ^@ Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1796616:A4V09_RS06595 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6Y1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/1796616:A4V09_RS02660 ^@ http://purl.uniprot.org/uniprot/A0A1C7I576 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/1796616:A4V09_RS15180 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDM2 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/1796616:A4V09_RS13965 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAW2 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS23920 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGI5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS11215 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9B0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS03370 ^@ http://purl.uniprot.org/uniprot/A0A1C7IJG8 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1796616:A4V09_RS00145 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7W1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS21730 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGS8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS05440 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6I9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.|||Cytoplasm|||Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. http://togogenome.org/gene/1796616:A4V09_RS19925 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDL0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS19270 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFF3 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1796616:A4V09_RS10075 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC15 ^@ Subcellular Location Annotation|||Subunit ^@ Homodimer.|||Secreted http://togogenome.org/gene/1796616:A4V09_RS02990 ^@ http://purl.uniprot.org/uniprot/A0A1C7I730 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS04010 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7L2 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1796616:A4V09_RS23520 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFM7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/1796616:A4V09_RS06215 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6Z4 ^@ Cofactor|||Similarity ^@ Belongs to the UPF0313 family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1796616:A4V09_RS23405 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHG7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Cell membrane|||Membrane|||O-acyltransferase that catalyzes D-alanylation of both teichoic acid and lipoteichoic acid (LTA). D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Catalyzes D-alanylation from DltC carrier protein. http://togogenome.org/gene/1796616:A4V09_RS11840 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9T6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/1796616:A4V09_RS13235 ^@ http://purl.uniprot.org/uniprot/A0A1C7IKM2 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1796616:A4V09_RS16045 ^@ http://purl.uniprot.org/uniprot/A0A1C7II19 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS06570 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB22 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1796616:A4V09_RS03240 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9F7 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 1 family. http://togogenome.org/gene/1796616:A4V09_RS07015 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFT5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1796616:A4V09_RS05895 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6P2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS08700 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAH2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1796616:A4V09_RS23355 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHG4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.|||Cell membrane|||Membrane|||Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. http://togogenome.org/gene/1796616:A4V09_RS11515 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9H3 ^@ Similarity ^@ Belongs to the thioesterase PaaI family. http://togogenome.org/gene/1796616:A4V09_RS11350 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9E2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/1796616:A4V09_RS08555 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9V8 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/1796616:A4V09_RS07655 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7Q4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 130 family. http://togogenome.org/gene/1796616:A4V09_RS15525 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDK2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aldolase class II family. RhaD subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS07875 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9T2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/1796616:A4V09_RS15650 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBR6 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1796616:A4V09_RS08220 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7X2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS02175 ^@ http://purl.uniprot.org/uniprot/A0A1C7I513 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/1796616:A4V09_RS04375 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG25 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS14670 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID67 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/1796616:A4V09_RS05420 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAG4 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/1796616:A4V09_RS12505 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICB4 ^@ Caution|||Function ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS22830 ^@ http://purl.uniprot.org/uniprot/A0A1C7IJH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS10225 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAP3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS16220 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS22265 ^@ http://purl.uniprot.org/uniprot/A0A1C7IER1 ^@ Similarity ^@ Belongs to the V-ATPase V0D/AC39 subunit family. http://togogenome.org/gene/1796616:A4V09_RS10260 ^@ http://purl.uniprot.org/uniprot/A0A1C7I900 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/1796616:A4V09_RS04725 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA45 ^@ Similarity ^@ Belongs to the CarB family. http://togogenome.org/gene/1796616:A4V09_RS02685 ^@ http://purl.uniprot.org/uniprot/A0A1C7I572 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/1796616:A4V09_RS18845 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID43 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS07975 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBT8 ^@ Function|||Similarity|||Subunit ^@ Associates with stalled 50S ribosomal subunits.|||Belongs to the NEMF family.|||Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. http://togogenome.org/gene/1796616:A4V09_RS11825 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDT6 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/1796616:A4V09_RS06950 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9M1 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/1796616:A4V09_RS06020 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8U6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1796616:A4V09_RS22235 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS13535 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICU8 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1796616:A4V09_RS16320 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBU5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/1796616:A4V09_RS12365 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID88 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS15890 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBL9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the arabinose isomerase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of L-arabinose to L-ribulose. http://togogenome.org/gene/1796616:A4V09_RS15635 ^@ http://purl.uniprot.org/uniprot/A0A1C7IKR5 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/1796616:A4V09_RS22290 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF11 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/1796616:A4V09_RS18165 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEU9 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1796616:A4V09_RS14980 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB59 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/1796616:A4V09_RS04130 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5T1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS04760 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9A7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS12525 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA04 ^@ Similarity ^@ Belongs to the cycloisomerase 2 family. http://togogenome.org/gene/1796616:A4V09_RS23400 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHK2 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.|||Belongs to the DltC family.|||Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS04535 ^@ http://purl.uniprot.org/uniprot/A0A1C7I603 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/1796616:A4V09_RS21815 ^@ http://purl.uniprot.org/uniprot/A0A1C7II61 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/1796616:A4V09_RS10030 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8Q7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1796616:A4V09_RS14070 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICV9 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/1796616:A4V09_RS23420 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFD5 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/1796616:A4V09_RS22735 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS12660 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICE3 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1796616:A4V09_RS04955 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6C5 ^@ Function|||Similarity ^@ Belongs to the PyrI family.|||Involved in allosteric regulation of aspartate carbamoyltransferase. http://togogenome.org/gene/1796616:A4V09_RS08945 ^@ http://purl.uniprot.org/uniprot/A0A1C7I882 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1796616:A4V09_RS13660 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICX3 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/1796616:A4V09_RS02165 ^@ http://purl.uniprot.org/uniprot/A0A1C7I746 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/1796616:A4V09_RS01345 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7H6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS12830 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC94 ^@ Similarity ^@ Belongs to the UPF0751 family. http://togogenome.org/gene/1796616:A4V09_RS11880 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC07 ^@ Similarity ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. http://togogenome.org/gene/1796616:A4V09_RS17565 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE93 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/1796616:A4V09_RS13575 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG23 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/1796616:A4V09_RS03185 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9E7 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/1796616:A4V09_RS16300 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS20295 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS15745 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDW1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1796616:A4V09_RS12680 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA33 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS21435 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS03465 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9J4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1796616:A4V09_RS04545 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA15 ^@ Similarity ^@ In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/1796616:A4V09_RS12035 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDX6 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/1796616:A4V09_RS08995 ^@ http://purl.uniprot.org/uniprot/A0A1C7I890 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS07900 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAX8 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/1796616:A4V09_RS19400 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDD2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS00905 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4F9 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS04440 ^@ http://purl.uniprot.org/uniprot/A0A1C7I664 ^@ Function|||Similarity ^@ Belongs to the QueH family.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). http://togogenome.org/gene/1796616:A4V09_RS13245 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAJ8 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/1796616:A4V09_RS04435 ^@ http://purl.uniprot.org/uniprot/A0A1C7I804 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1796616:A4V09_RS05715 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8E8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiM family.|||Cell membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Membrane|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/1796616:A4V09_RS23890 ^@ http://purl.uniprot.org/uniprot/A0A1C7IKA2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/1796616:A4V09_RS14675 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS15210 ^@ http://purl.uniprot.org/uniprot/A0A1C7IER7 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/1796616:A4V09_RS12770 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC85 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1796616:A4V09_RS03245 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7P3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS07615 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9D1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1796616:A4V09_RS21075 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS23425 ^@ http://purl.uniprot.org/uniprot/A0A1C7IH39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS08650 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA62 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1796616:A4V09_RS00405 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5T5 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/1796616:A4V09_RS04015 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8X5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS13015 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC40 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS00355 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHS8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1796616:A4V09_RS03575 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5I6 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1796616:A4V09_RS08110 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9P0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS00505 ^@ http://purl.uniprot.org/uniprot/A0A1C7I447 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1796616:A4V09_RS17580 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICH2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/1796616:A4V09_RS13155 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS10485 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8Z1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS03495 ^@ http://purl.uniprot.org/uniprot/A0A1C7II14 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1796616:A4V09_RS20530 ^@ http://purl.uniprot.org/uniprot/A0A1C7IKY2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/1796616:A4V09_RS11650 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9M8 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS05655 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6M5 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/1796616:A4V09_RS00160 ^@ http://purl.uniprot.org/uniprot/A0A1C7I431 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1796616:A4V09_RS10145 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICX7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1796616:A4V09_RS08950 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA40 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/1796616:A4V09_RS16245 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDX9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/1796616:A4V09_RS20445 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDU8 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1796616:A4V09_RS19820 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIL5 ^@ Function|||Similarity ^@ Belongs to the ROK (NagC/XylR) family.|||Transcriptional repressor of xylose-utilizing enzymes. http://togogenome.org/gene/1796616:A4V09_RS15675 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBH8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1796616:A4V09_RS01770 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6N6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS22785 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS03635 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5Q0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/1796616:A4V09_RS04145 ^@ http://purl.uniprot.org/uniprot/A0A1C7I845 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS07860 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7S8 ^@ Function|||Similarity ^@ Belongs to the PemK/MazF family.|||Toxic component of a type II toxin-antitoxin (TA) system. http://togogenome.org/gene/1796616:A4V09_RS11800 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG02 ^@ Function|||Similarity ^@ Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/1796616:A4V09_RS21790 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGQ0 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1796616:A4V09_RS20815 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE13 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/1796616:A4V09_RS06340 ^@ http://purl.uniprot.org/uniprot/A0A1C7I906 ^@ Function|||Similarity ^@ Belongs to the PduL family.|||Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. http://togogenome.org/gene/1796616:A4V09_RS10440 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8Y2 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/1796616:A4V09_RS20285 ^@ http://purl.uniprot.org/uniprot/A0A1C7II54 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 1 family. http://togogenome.org/gene/1796616:A4V09_RS04910 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6E7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/1796616:A4V09_RS15290 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDG9 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. http://togogenome.org/gene/1796616:A4V09_RS05650 ^@ http://purl.uniprot.org/uniprot/A0A1C7II47 ^@ Similarity ^@ Belongs to the CobT family. http://togogenome.org/gene/1796616:A4V09_RS14750 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS15300 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBC1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/1796616:A4V09_RS16410 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG65 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/1796616:A4V09_RS15690 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDV1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/1796616:A4V09_RS04110 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5P1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS18160 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF24 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1796616:A4V09_RS00980 ^@ http://purl.uniprot.org/uniprot/A0A1C7I632 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/1796616:A4V09_RS23305 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS14930 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEL5 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/1796616:A4V09_RS08285 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7X6 ^@ Similarity ^@ Belongs to the type A lantibiotic family. http://togogenome.org/gene/1796616:A4V09_RS12425 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDA1 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/1796616:A4V09_RS11580 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIC3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS02320 ^@ http://purl.uniprot.org/uniprot/A0A1C7I517 ^@ Function|||Similarity ^@ Belongs to the RecD family. RecD-like subfamily.|||DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity. http://togogenome.org/gene/1796616:A4V09_RS11275 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDJ0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/1796616:A4V09_RS10165 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8T4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1796616:A4V09_RS07995 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7T2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS06565 ^@ http://purl.uniprot.org/uniprot/A0A1C7I750 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1796616:A4V09_RS22730 ^@ http://purl.uniprot.org/uniprot/A0A1C7IJF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS08695 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC63 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/1796616:A4V09_RS15040 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID33 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS23935 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHB8 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/1796616:A4V09_RS06150 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8L7 ^@ Function|||Similarity ^@ Belongs to the alpha/beta-type SASP family.|||SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. http://togogenome.org/gene/1796616:A4V09_RS22410 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGL4 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/1796616:A4V09_RS04290 ^@ http://purl.uniprot.org/uniprot/A0A1C7I619 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/1796616:A4V09_RS12460 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA50 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/1796616:A4V09_RS07940 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7S3 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/1796616:A4V09_RS18895 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDB1 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/1796616:A4V09_RS22965 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIT9 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS11705 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDR8 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/1796616:A4V09_RS03945 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5U1 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/1796616:A4V09_RS15780 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBK0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1796616:A4V09_RS21885 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEM1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1796616:A4V09_RS01275 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4B9 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/1796616:A4V09_RS01375 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFJ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS10460 ^@ http://purl.uniprot.org/uniprot/A0A1C7I928 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the methylaspartate mutase GlmE subunit family.|||Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).|||Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS06200 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8M8 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/1796616:A4V09_RS09250 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8G6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS05620 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6J2 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1796616:A4V09_RS17420 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEP1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/1796616:A4V09_RS22795 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFA4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS14965 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDB4 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/1796616:A4V09_RS08635 ^@ http://purl.uniprot.org/uniprot/A0A1C7I862 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1796616:A4V09_RS16265 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBT7 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HSP33 family.|||Cytoplasm|||Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.|||Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive. http://togogenome.org/gene/1796616:A4V09_RS01995 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFQ6 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/1796616:A4V09_RS22200 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGI0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS04000 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5V5 ^@ Cofactor|||Similarity ^@ Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1796616:A4V09_RS05720 ^@ http://purl.uniprot.org/uniprot/A0A1C7II13 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/1796616:A4V09_RS06240 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6Y0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecU family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation. http://togogenome.org/gene/1796616:A4V09_RS23285 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHG2 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/1796616:A4V09_RS00210 ^@ http://purl.uniprot.org/uniprot/A0A1C7I440 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1796616:A4V09_RS19580 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDE0 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit.|||Homotetramer. http://togogenome.org/gene/1796616:A4V09_RS03980 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9S2 ^@ Similarity ^@ Belongs to the PHP hydrolase family. HisK subfamily. http://togogenome.org/gene/1796616:A4V09_RS10300 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS16545 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC77 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS16345 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBY3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS04990 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6F7 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1796616:A4V09_RS15015 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDJ7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS06000 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6R2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/1796616:A4V09_RS05070 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9F5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS16215 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFA1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 25 family. http://togogenome.org/gene/1796616:A4V09_RS01035 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4E2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS19055 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID54 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS17140 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFQ1 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/1796616:A4V09_RS17555 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICD1 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/1796616:A4V09_RS06155 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA19 ^@ Caution|||Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS02170 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6V7 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS24045 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFV3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/1796616:A4V09_RS10890 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGB4 ^@ Similarity ^@ Belongs to the diacylglycerol/lipid kinase family. http://togogenome.org/gene/1796616:A4V09_RS14960 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDI7 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.|||In the N-terminal section; belongs to the DHNA family. http://togogenome.org/gene/1796616:A4V09_RS19500 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIK7 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS01990 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4P8 ^@ Similarity ^@ Belongs to the urocanase family. http://togogenome.org/gene/1796616:A4V09_RS03825 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5U8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS01120 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4I5 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/1796616:A4V09_RS06025 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6Y3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrB/RnfD family.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1796616:A4V09_RS15030 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB77 ^@ Caution|||Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.|||Belongs to the biotin--protein ligase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS05165 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6E0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/1796616:A4V09_RS23275 ^@ http://purl.uniprot.org/uniprot/A0A1C7IJQ3 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/1796616:A4V09_RS09000 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA46 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/1796616:A4V09_RS05415 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6K0 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/1796616:A4V09_RS23455 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHH9 ^@ Function|||Similarity ^@ Belongs to the ROK (NagC/XylR) family.|||Transcriptional repressor of xylose-utilizing enzymes. http://togogenome.org/gene/1796616:A4V09_RS12095 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS02945 ^@ http://purl.uniprot.org/uniprot/A0A1C7I566 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/1796616:A4V09_RS21190 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE81 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/1796616:A4V09_RS20135 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDL2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/1796616:A4V09_RS05100 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8A7 ^@ Similarity|||Subunit ^@ Belongs to the UPF0210 family.|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS23905 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHP7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS19440 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFI3 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS05615 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9Q3 ^@ Function|||Similarity ^@ Belongs to the CbiD family.|||Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. http://togogenome.org/gene/1796616:A4V09_RS19550 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFK2 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/1796616:A4V09_RS18065 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICQ2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS07660 ^@ http://purl.uniprot.org/uniprot/A0A1C7II75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS17655 ^@ http://purl.uniprot.org/uniprot/A0A1C7IKU1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/1796616:A4V09_RS12760 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEB3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MrnC RNase family.|||Cytoplasm|||Homodimer.|||Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors. http://togogenome.org/gene/1796616:A4V09_RS21735 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGP1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS12435 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9X0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS13685 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAJ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/1796616:A4V09_RS12205 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9S7 ^@ Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family. http://togogenome.org/gene/1796616:A4V09_RS03590 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7U9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.|||Belongs to the AccA family.|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm|||In the C-terminal section; belongs to the AccA family.|||In the N-terminal section; belongs to the AccD/PCCB family. http://togogenome.org/gene/1796616:A4V09_RS02005 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8S4 ^@ PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS18360 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEN6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS12685 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBX4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS16135 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDV0 ^@ Function|||Similarity ^@ Belongs to the alpha/beta-type SASP family.|||SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. http://togogenome.org/gene/1796616:A4V09_RS17660 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICF4 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS15530 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBQ1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the rhamnose isomerase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the interconversion of L-rhamnose and L-rhamnulose.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS05160 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6I0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS03215 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5A2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/1796616:A4V09_RS15870 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBM6 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 1 family. http://togogenome.org/gene/1796616:A4V09_RS01685 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4Q1 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/1796616:A4V09_RS10240 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8Z5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/1796616:A4V09_RS09210 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8C1 ^@ Similarity ^@ Belongs to the ThiD family. http://togogenome.org/gene/1796616:A4V09_RS11780 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9S6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TER reductase family.|||Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA).|||Monomer. http://togogenome.org/gene/1796616:A4V09_RS10380 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8X3 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/1796616:A4V09_RS22590 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGP0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/1796616:A4V09_RS20345 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG45 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1796616:A4V09_RS23370 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFC5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS02895 ^@ http://purl.uniprot.org/uniprot/A0A1C7I557 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/1796616:A4V09_RS23875 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFI1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/1796616:A4V09_RS21335 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS10515 ^@ http://purl.uniprot.org/uniprot/A0A1C7I938 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS19835 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDH8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1796616:A4V09_RS11805 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICZ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/1796616:A4V09_RS05835 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9U5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS23205 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFB2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/1796616:A4V09_RS20010 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFY7 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/1796616:A4V09_RS19540 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGN7 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/1796616:A4V09_RS15875 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDI5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS10740 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBH4 ^@ Function ^@ Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase. http://togogenome.org/gene/1796616:A4V09_RS00960 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6A5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein S18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS04225 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7Q5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS09820 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBW6 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/1796616:A4V09_RS23005 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGF2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/1796616:A4V09_RS14530 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEE0 ^@ Function|||Similarity ^@ Belongs to the vsr family.|||May nick specific sequences that contain T:G mispairs resulting from m5C-deamination. http://togogenome.org/gene/1796616:A4V09_RS11230 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBP6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS21060 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGC8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/1796616:A4V09_RS02595 ^@ http://purl.uniprot.org/uniprot/A0A1C7I852 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/1796616:A4V09_RS08875 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAB2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS02580 ^@ http://purl.uniprot.org/uniprot/A0A1C7I549 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/1796616:A4V09_RS08515 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA37 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1796616:A4V09_RS05380 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8G7 ^@ Similarity ^@ Belongs to the CpsD/CapB family. http://togogenome.org/gene/1796616:A4V09_RS09015 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8E4 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/1796616:A4V09_RS05240 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6C0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/1796616:A4V09_RS17145 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC75 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS14485 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB10 ^@ Similarity ^@ Belongs to the DNA polymerase type-A family. http://togogenome.org/gene/1796616:A4V09_RS09245 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAG7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS04160 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5Y4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS04265 ^@ http://purl.uniprot.org/uniprot/A0A1C7I604 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/1796616:A4V09_RS02390 ^@ http://purl.uniprot.org/uniprot/A0A1C7I786 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/1796616:A4V09_RS12655 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE88 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/1796616:A4V09_RS20585 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG38 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/1796616:A4V09_RS16630 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDU6 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/1796616:A4V09_RS02625 ^@ http://purl.uniprot.org/uniprot/A0A1C7I736 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/1796616:A4V09_RS15555 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG87 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/1796616:A4V09_RS02995 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS20250 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDZ7 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/1796616:A4V09_RS11295 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9D2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS10400 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC80 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/1796616:A4V09_RS22220 ^@ http://purl.uniprot.org/uniprot/A0A1C7IJ65 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/1796616:A4V09_RS02315 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFP2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS14035 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS00150 ^@ http://purl.uniprot.org/uniprot/A0A1C7I656 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS14655 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB33 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS07840 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9H4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0053 family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS02535 ^@ http://purl.uniprot.org/uniprot/A0A1C7I839 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS15575 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFR4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS08940 ^@ http://purl.uniprot.org/uniprot/A0A1C7I894 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/1796616:A4V09_RS17500 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICF9 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/1796616:A4V09_RS14885 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB41 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS07795 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAV7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/1796616:A4V09_RS08500 ^@ http://purl.uniprot.org/uniprot/A0A1C7IKG3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/1796616:A4V09_RS03565 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7D7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/1796616:A4V09_RS15190 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBI5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/1796616:A4V09_RS15010 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFG7 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/1796616:A4V09_RS02735 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7E4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/1796616:A4V09_RS02635 ^@ http://purl.uniprot.org/uniprot/A0A1C7I560 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/1796616:A4V09_RS20575 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIB1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAD-like hydrolase superfamily. PhnX family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Involved in phosphonate degradation. http://togogenome.org/gene/1796616:A4V09_RS02120 ^@ http://purl.uniprot.org/uniprot/A0A1C7I502 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/1796616:A4V09_RS10920 ^@ http://purl.uniprot.org/uniprot/A0A1C7I960 ^@ Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family. http://togogenome.org/gene/1796616:A4V09_RS21405 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE94 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS15270 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBB0 ^@ Similarity ^@ Belongs to the UPF0297 family. http://togogenome.org/gene/1796616:A4V09_RS23465 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS00085 ^@ http://purl.uniprot.org/uniprot/A0A1C7I646 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS07235 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7J1 ^@ Similarity ^@ Belongs to the membrane-bound acyltransferase family. http://togogenome.org/gene/1796616:A4V09_RS06470 ^@ http://purl.uniprot.org/uniprot/A0A1C7I725 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS00240 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6Z1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS13280 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEK8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the diaminopimelate dehydrogenase family.|||Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS01520 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4G5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS03975 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5U9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS01710 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6M8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS17285 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS05485 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8I6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS16330 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDQ3 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS22165 ^@ http://purl.uniprot.org/uniprot/A0A1C7IH05 ^@ Similarity ^@ Belongs to the xanthine dehydrogenase family. http://togogenome.org/gene/1796616:A4V09_RS20145 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFI4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/1796616:A4V09_RS09940 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS12920 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS14545 ^@ http://purl.uniprot.org/uniprot/A0A1C7IKP3 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1796616:A4V09_RS06070 ^@ http://purl.uniprot.org/uniprot/A0A1C7I939 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/1796616:A4V09_RS22745 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF94 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 32 family.|||Cytoplasm|||Enables the bacterium to metabolize sucrose as a sole carbon source. http://togogenome.org/gene/1796616:A4V09_RS15005 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB90 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1796616:A4V09_RS15615 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEY2 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1796616:A4V09_RS00245 ^@ http://purl.uniprot.org/uniprot/A0A1C7I3V2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS12975 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAB1 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/1796616:A4V09_RS03935 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7R2 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/1796616:A4V09_RS14000 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAS8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS09885 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB17 ^@ Similarity ^@ Belongs to the FBPase class 3 family. http://togogenome.org/gene/1796616:A4V09_RS15990 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBP4 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit.|||Homotetramer. http://togogenome.org/gene/1796616:A4V09_RS21400 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEK9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/1796616:A4V09_RS04905 ^@ http://purl.uniprot.org/uniprot/A0A1C7I878 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/1796616:A4V09_RS02195 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7X5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/1796616:A4V09_RS03280 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5D1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS21605 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS05955 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6U8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/1796616:A4V09_RS03860 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5T0 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/1796616:A4V09_RS03225 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8H9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of glycine to tRNA(Gly).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS00020 ^@ http://purl.uniprot.org/uniprot/A0A1C7I637 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/1796616:A4V09_RS10455 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8Y5 ^@ Similarity|||Subunit ^@ Belongs to the methylaspartate ammonia-lyase family.|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS17115 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICF3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/1796616:A4V09_RS12340 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS19405 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF57 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS17505 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE82 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS13810 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAK0 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1796616:A4V09_RS21040 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE52 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS03715 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5P3 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/1796616:A4V09_RS05140 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6F5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1796616:A4V09_RS16530 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG80 ^@ Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 51 family.|||Homohexamer; trimer of dimers. http://togogenome.org/gene/1796616:A4V09_RS07955 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAY7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1796616:A4V09_RS06745 ^@ http://purl.uniprot.org/uniprot/A0A1C7I777 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/1796616:A4V09_RS15375 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEU1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS13845 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAU2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS16585 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS20290 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG27 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS15715 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBJ6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1796616:A4V09_RS05685 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAL3 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. http://togogenome.org/gene/1796616:A4V09_RS11030 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICK0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS23330 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFD2 ^@ Similarity ^@ Belongs to the YoeB family. http://togogenome.org/gene/1796616:A4V09_RS18465 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGD8 ^@ Function|||Similarity ^@ Belongs to the RecD family. RecD-like subfamily.|||DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity. http://togogenome.org/gene/1796616:A4V09_RS17680 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFZ1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS03820 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7P4 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1796616:A4V09_RS04540 ^@ http://purl.uniprot.org/uniprot/A0A1C7I657 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/1796616:A4V09_RS23810 ^@ http://purl.uniprot.org/uniprot/A0A1C7IJ73 ^@ PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS21560 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIU9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1796616:A4V09_RS23915 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFF6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS06135 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6W3 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/1796616:A4V09_RS16455 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFD8 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/1796616:A4V09_RS00490 ^@ http://purl.uniprot.org/uniprot/A0A1C7I623 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS06120 ^@ http://purl.uniprot.org/uniprot/A0A1C7I953 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1796616:A4V09_RS06930 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAG2 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/1796616:A4V09_RS22800 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEX9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/1796616:A4V09_RS04340 ^@ http://purl.uniprot.org/uniprot/A0A1C7I933 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS09900 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8M9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1796616:A4V09_RS11150 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9A5 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/1796616:A4V09_RS13540 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICM1 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1796616:A4V09_RS23815 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFH2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS23080 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIW1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/1796616:A4V09_RS05950 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6Q2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1796616:A4V09_RS01955 ^@ http://purl.uniprot.org/uniprot/A0A1C7I706 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1796616:A4V09_RS05675 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6K2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS04590 ^@ http://purl.uniprot.org/uniprot/A0A1C7I977 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/1796616:A4V09_RS03870 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9Q1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS11060 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBC3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS23095 ^@ http://purl.uniprot.org/uniprot/A0A1C7IJM4 ^@ Similarity ^@ Belongs to the UPF0735 family. http://togogenome.org/gene/1796616:A4V09_RS23070 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF79 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/1796616:A4V09_RS01655 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4S8 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/1796616:A4V09_RS03995 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5X9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/1796616:A4V09_RS06320 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6W9 ^@ Subcellular Location Annotation ^@ Bacterial microcompartment http://togogenome.org/gene/1796616:A4V09_RS22955 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS15680 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBK7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/1796616:A4V09_RS18370 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICT1 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/1796616:A4V09_RS00455 ^@ http://purl.uniprot.org/uniprot/A0A1C7I3W5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS10410 ^@ http://purl.uniprot.org/uniprot/A0A1C7I920 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/1796616:A4V09_RS12515 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA60 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS21725 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS15140 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB93 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/1796616:A4V09_RS05080 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6E6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.|||Single-chain monomer with multiple functions. http://togogenome.org/gene/1796616:A4V09_RS04920 ^@ http://purl.uniprot.org/uniprot/A0A1C7II37 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/1796616:A4V09_RS09385 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8E9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1796616:A4V09_RS23440 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFF0 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1796616:A4V09_RS02270 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8X6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS18040 ^@ http://purl.uniprot.org/uniprot/A0A1C7IES8 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS11265 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9B8 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1796616:A4V09_RS17035 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC54 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1796616:A4V09_RS08935 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8B8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1796616:A4V09_RS01305 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6F4 ^@ Similarity ^@ Belongs to the class-D beta-lactamase family. http://togogenome.org/gene/1796616:A4V09_RS05820 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6Q6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ScpA family.|||Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.|||Cytoplasm|||Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. http://togogenome.org/gene/1796616:A4V09_RS06045 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9Z3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.|||Binds 3 [4Fe-4S] clusters.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1796616:A4V09_RS10625 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS15785 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBM4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1796616:A4V09_RS01045 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6K6 ^@ Similarity ^@ Belongs to the polypeptide deformylase family. http://togogenome.org/gene/1796616:A4V09_RS12650 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA48 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. http://togogenome.org/gene/1796616:A4V09_RS05020 ^@ http://purl.uniprot.org/uniprot/A0A1C7I678 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1796616:A4V09_RS17750 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS12010 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9S5 ^@ Similarity ^@ Belongs to the arylamine N-acetyltransferase family. http://togogenome.org/gene/1796616:A4V09_RS12885 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICA1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS21235 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEH9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/1796616:A4V09_RS20475 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDT3 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1796616:A4V09_RS15380 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBD0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/1796616:A4V09_RS12175 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBY1 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1796616:A4V09_RS09240 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAS0 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/1796616:A4V09_RS21025 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE51 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit.|||Homotetramer. http://togogenome.org/gene/1796616:A4V09_RS20340 ^@ http://purl.uniprot.org/uniprot/A0A1C7II71 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/1796616:A4V09_RS22780 ^@ http://purl.uniprot.org/uniprot/A0A1C7IJG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS18230 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICQ6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1796616:A4V09_RS21395 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS06040 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8K2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1796616:A4V09_RS08915 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICB8 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/1796616:A4V09_RS20965 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE17 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 42 family. http://togogenome.org/gene/1796616:A4V09_RS23365 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS15265 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIE3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS06580 ^@ http://purl.uniprot.org/uniprot/A0A1C7I943 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/1796616:A4V09_RS16365 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDZ8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/1796616:A4V09_RS17720 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICQ3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/1796616:A4V09_RS15230 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDN5 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1796616:A4V09_RS01535 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6T6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS21540 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGE2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS21625 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEP7 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1796616:A4V09_RS02415 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6S5 ^@ Similarity ^@ Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family. http://togogenome.org/gene/1796616:A4V09_RS23310 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS15260 ^@ http://purl.uniprot.org/uniprot/A0A1C7IES3 ^@ Similarity ^@ Belongs to the UPF0473 family. http://togogenome.org/gene/1796616:A4V09_RS15315 ^@ http://purl.uniprot.org/uniprot/A0A1C7IET6 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/1796616:A4V09_RS02200 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4U2 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/1796616:A4V09_RS06515 ^@ http://purl.uniprot.org/uniprot/A0A1C7I931 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/1796616:A4V09_RS11260 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICN4 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/1796616:A4V09_RS06590 ^@ http://purl.uniprot.org/uniprot/A0A1C7I744 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/1796616:A4V09_RS02300 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6Q3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1796616:A4V09_RS03125 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5F5 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/1796616:A4V09_RS04455 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5U7 ^@ Similarity ^@ Belongs to the type IA topoisomerase family. http://togogenome.org/gene/1796616:A4V09_RS09985 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8U8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS12615 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG12 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/1796616:A4V09_RS12270 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC73 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. http://togogenome.org/gene/1796616:A4V09_RS10445 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAT1 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/1796616:A4V09_RS08550 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7Z7 ^@ Similarity ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. http://togogenome.org/gene/1796616:A4V09_RS18085 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICM7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1796616:A4V09_RS23145 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFA3 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/1796616:A4V09_RS18020 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICL5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS19000 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID38 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS12740 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBY7 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS01360 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8G3 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS14660 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFB3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1796616:A4V09_RS08045 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7U1 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/1796616:A4V09_RS12715 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0053 family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS10135 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8S7 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/1796616:A4V09_RS22825 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS05395 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6A1 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/1796616:A4V09_RS16285 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBU1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS20185 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFV9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/1796616:A4V09_RS05660 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6F2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS10690 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBG5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1796616:A4V09_RS10195 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICY7 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/1796616:A4V09_RS03785 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7H8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/1796616:A4V09_RS19960 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFX8 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/1796616:A4V09_RS08645 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAF7 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS08125 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7U3 ^@ Similarity ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family. http://togogenome.org/gene/1796616:A4V09_RS00930 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7B1 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1796616:A4V09_RS02640 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4Z3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Cytoplasm|||Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. http://togogenome.org/gene/1796616:A4V09_RS10605 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICC6 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/1796616:A4V09_RS18750 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHC8 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/1796616:A4V09_RS17575 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICE0 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/1796616:A4V09_RS24050 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFH6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CutC family.|||Cytoplasm|||Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case. http://togogenome.org/gene/1796616:A4V09_RS05125 ^@ http://purl.uniprot.org/uniprot/A0A1C7I847 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TmcAL family.|||Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS19775 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFU8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS01615 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6D9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS23645 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFD9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/1796616:A4V09_RS01920 ^@ http://purl.uniprot.org/uniprot/A0A1V0QEZ4 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/1796616:A4V09_RS15500 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG93 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS04170 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7P5 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/1796616:A4V09_RS18735 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICZ8 ^@ Caution|||Function ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS17425 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEG3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the CRISPR-associated exonuclease Cas4 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).|||Mg(2+) or Mn(2+) required for ssDNA cleavage activity. http://togogenome.org/gene/1796616:A4V09_RS01610 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4G3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS13135 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAH0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1796616:A4V09_RS15765 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBK6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1796616:A4V09_RS23035 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF83 ^@ Similarity ^@ In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.|||In the N-terminal section; belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1796616:A4V09_RS19605 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDN6 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit.|||Homotetramer. http://togogenome.org/gene/1796616:A4V09_RS14200 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAS3 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/1796616:A4V09_RS03450 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8M4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/1796616:A4V09_RS04025 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5W6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/1796616:A4V09_RS06755 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8X9 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/1796616:A4V09_RS06065 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAT5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/1796616:A4V09_RS07945 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7P1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane|||This protein catalyzes the committed step to the synthesis of the acidic phospholipids. http://togogenome.org/gene/1796616:A4V09_RS05000 ^@ http://purl.uniprot.org/uniprot/A0A1C7I634 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/1796616:A4V09_RS10230 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC50 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS13555 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAH7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS20130 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDX3 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1796616:A4V09_RS20380 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHC5 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/1796616:A4V09_RS02520 ^@ http://purl.uniprot.org/uniprot/A0A1C7I541 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS11245 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9C2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS03905 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7J7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS00090 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5W4 ^@ Function ^@ Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. http://togogenome.org/gene/1796616:A4V09_RS03880 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7Q3 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Requires K(+) for maximal activity.|||Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. http://togogenome.org/gene/1796616:A4V09_RS21315 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHX7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/1796616:A4V09_RS05780 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFR9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS14995 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEM7 ^@ Similarity ^@ Belongs to the TelA family. http://togogenome.org/gene/1796616:A4V09_RS21000 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIJ7 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS21250 ^@ http://purl.uniprot.org/uniprot/A0A1C7IKZ3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. http://togogenome.org/gene/1796616:A4V09_RS21470 ^@ http://purl.uniprot.org/uniprot/A0A1C7IED1 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. LacC subfamily.|||Belongs to the carbohydrate kinase pfkB family. http://togogenome.org/gene/1796616:A4V09_RS15795 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDX1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1796616:A4V09_RS05190 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6A8 ^@ Function|||Similarity ^@ Belongs to the LarC family.|||Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. http://togogenome.org/gene/1796616:A4V09_RS11040 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9C1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MurCDEF family. MurT subfamily.|||Forms a heterodimer with GatD.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue. http://togogenome.org/gene/1796616:A4V09_RS16390 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS04685 ^@ http://purl.uniprot.org/uniprot/A0A1C7I842 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/1796616:A4V09_RS06770 ^@ http://purl.uniprot.org/uniprot/A0A1C7I792 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/1796616:A4V09_RS11520 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBB3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS04515 ^@ http://purl.uniprot.org/uniprot/A0A1C7I641 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS07645 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9Y4 ^@ Function|||Similarity ^@ Belongs to the glycosyl hydrolase 130 family.|||Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose. http://togogenome.org/gene/1796616:A4V09_RS03855 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5N4 ^@ Cofactor|||Function|||Subcellular Location Annotation ^@ Binds 1 Ca(2+) ion per subunit.|||Cytoplasm|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS22255 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS09200 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA74 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS16295 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS08000 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7Q7 ^@ Function|||Similarity ^@ Belongs to the CheD family.|||Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis. http://togogenome.org/gene/1796616:A4V09_RS07915 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBS9 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1796616:A4V09_RS02810 ^@ http://purl.uniprot.org/uniprot/A0A1C7I526 ^@ Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 51 family.|||Homohexamer; trimer of dimers. http://togogenome.org/gene/1796616:A4V09_RS22175 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGW6 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/1796616:A4V09_RS18235 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS13180 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICF6 ^@ Similarity ^@ Belongs to the helicase family. RAD3/XPD subfamily. http://togogenome.org/gene/1796616:A4V09_RS01540 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS20485 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGJ0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/1796616:A4V09_RS11385 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDL3 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1796616:A4V09_RS15740 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFU7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1796616:A4V09_RS23705 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFF2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS15355 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBD5 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1796616:A4V09_RS07040 ^@ http://purl.uniprot.org/uniprot/A0A1C7I930 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS16975 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFM5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS05230 ^@ http://purl.uniprot.org/uniprot/A0A1C7I864 ^@ Function|||Similarity ^@ Belongs to the UPF0122 family.|||Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. http://togogenome.org/gene/1796616:A4V09_RS14040 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS12725 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS11135 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBD6 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/1796616:A4V09_RS07710 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7R7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS21890 ^@ http://purl.uniprot.org/uniprot/A0A1C7IJ07 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS23735 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS14130 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAR9 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/1796616:A4V09_RS10980 ^@ http://purl.uniprot.org/uniprot/A0A1C7I969 ^@ Similarity ^@ Belongs to the SfsA family. http://togogenome.org/gene/1796616:A4V09_RS21475 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG60 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS07965 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7U8 ^@ Similarity ^@ Belongs to the RemA family. http://togogenome.org/gene/1796616:A4V09_RS13150 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC59 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/1796616:A4V09_RS16120 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBU0 ^@ Similarity ^@ Belongs to the folylpolyglutamate synthase family. http://togogenome.org/gene/1796616:A4V09_RS14445 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAW8 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1796616:A4V09_RS18280 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS22260 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIE2 ^@ Function|||Similarity ^@ Belongs to the V-ATPase E subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1796616:A4V09_RS23015 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS00295 ^@ http://purl.uniprot.org/uniprot/A0A1C7I700 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpC family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/1796616:A4V09_RS10345 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8W7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS04670 ^@ http://purl.uniprot.org/uniprot/A0A1C7I677 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS12420 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBS6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 42 family. http://togogenome.org/gene/1796616:A4V09_RS21375 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEA7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/1796616:A4V09_RS04220 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5Q7 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1796616:A4V09_RS01585 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6U6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane|||This protein catalyzes the committed step to the synthesis of the acidic phospholipids. http://togogenome.org/gene/1796616:A4V09_RS05965 ^@ http://purl.uniprot.org/uniprot/A0A1C7I923 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the OadG family.|||Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.|||Cell membrane http://togogenome.org/gene/1796616:A4V09_RS02240 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4S3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS06425 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA70 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1796616:A4V09_RS07810 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBQ7 ^@ Cofactor ^@ Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/1796616:A4V09_RS16870 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDY2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS04085 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9U1 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/1796616:A4V09_RS13255 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAC5 ^@ Cofactor|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/1796616:A4V09_RS11885 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBS8 ^@ Similarity ^@ Belongs to the type II topoisomerase GyrB family. http://togogenome.org/gene/1796616:A4V09_RS07865 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBR7 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/1796616:A4V09_RS09755 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8K0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS17475 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEH5 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1796616:A4V09_RS05750 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8X1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/1796616:A4V09_RS13785 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAT4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS08405 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9T9 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1796616:A4V09_RS13335 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICR7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1796616:A4V09_RS03380 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFR3 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1796616:A4V09_RS15915 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBW7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS06095 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8K9 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1796616:A4V09_RS23725 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHL9 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS01095 ^@ http://purl.uniprot.org/uniprot/A0A1C7I491 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/1796616:A4V09_RS08930 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAC0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/1796616:A4V09_RS15255 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID70 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/1796616:A4V09_RS02620 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7C6 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS14990 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID24 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/1796616:A4V09_RS05590 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8K7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS01575 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4N2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS16255 ^@ http://purl.uniprot.org/uniprot/A0A1C7IKS1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1796616:A4V09_RS13800 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS00935 ^@ http://purl.uniprot.org/uniprot/A0A1C7I474 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Cell membrane|||Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS00975 ^@ http://purl.uniprot.org/uniprot/A0A1C7I457 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/1796616:A4V09_RS02870 ^@ http://purl.uniprot.org/uniprot/A0A1C7I595 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS01560 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6C8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS03290 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9G7 ^@ Caution|||Function ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS02765 ^@ http://purl.uniprot.org/uniprot/A0A1C7I884 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type-I 3-dehydroquinase family.|||Homodimer.|||Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS16515 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS03830 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5R0 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/1796616:A4V09_RS01735 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFS7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0053 family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS18210 ^@ http://purl.uniprot.org/uniprot/A0A1C7IH21 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1796616:A4V09_RS12860 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA43 ^@ Similarity ^@ Belongs to the ribulokinase family. http://togogenome.org/gene/1796616:A4V09_RS13455 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS09220 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICG8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/1796616:A4V09_RS10560 ^@ http://purl.uniprot.org/uniprot/A0A1C7I902 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/1796616:A4V09_RS10010 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8Q1 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/1796616:A4V09_RS02815 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6Z7 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS13795 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAL6 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/1796616:A4V09_RS06030 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6U5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RnfG family.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1796616:A4V09_RS23850 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIB8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS22850 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEY9 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/1796616:A4V09_RS00140 ^@ http://purl.uniprot.org/uniprot/A0A1C7I400 ^@ Similarity ^@ Belongs to the cycloisomerase 2 family. http://togogenome.org/gene/1796616:A4V09_RS05430 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8H6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/1796616:A4V09_RS21365 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG39 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS16010 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS07920 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA34 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1796616:A4V09_RS05995 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9Y3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS04765 ^@ http://purl.uniprot.org/uniprot/A0A1C7I640 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS15700 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDM5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1796616:A4V09_RS13275 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAF8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS18125 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICR1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1796616:A4V09_RS12450 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICA6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS02985 ^@ http://purl.uniprot.org/uniprot/A0A1C7I562 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1796616:A4V09_RS21045 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE79 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS08595 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA53 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS16505 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDS7 ^@ Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 51 family.|||Homohexamer; trimer of dimers. http://togogenome.org/gene/1796616:A4V09_RS22845 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFA8 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1796616:A4V09_RS19920 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDI9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 65 family. http://togogenome.org/gene/1796616:A4V09_RS00550 ^@ http://purl.uniprot.org/uniprot/A0A1C7I499 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS05705 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6N4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS16450 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDR6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 39 family. http://togogenome.org/gene/1796616:A4V09_RS22765 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIP6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS02190 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6N3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GdpP/PdeA phosphodiesterase family.|||Cell membrane|||For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.|||Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP). http://togogenome.org/gene/1796616:A4V09_RS20685 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS23560 ^@ http://purl.uniprot.org/uniprot/A0A1C7IJV6 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1796616:A4V09_RS06035 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6N1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1796616:A4V09_RS15150 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS20470 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE46 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1796616:A4V09_RS05475 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAH4 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/1796616:A4V09_RS16605 ^@ http://purl.uniprot.org/uniprot/A0A1C7IK00 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/1796616:A4V09_RS11140 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9F0 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS04635 ^@ http://purl.uniprot.org/uniprot/A0A1C7I691 ^@ Similarity ^@ Belongs to the peptidase S51 family. http://togogenome.org/gene/1796616:A4V09_RS09420 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG94 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1796616:A4V09_RS11195 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9B3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/1796616:A4V09_RS02465 ^@ http://purl.uniprot.org/uniprot/A0A1C7I531 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1796616:A4V09_RS00300 ^@ http://purl.uniprot.org/uniprot/A0A1C7I3W1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS25280 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBF4 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS10340 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS23040 ^@ http://purl.uniprot.org/uniprot/A0A1C7IJL2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1796616:A4V09_RS17355 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEN2 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/1796616:A4V09_RS16495 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS07210 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7C1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS23020 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS15815 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBL7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1796616:A4V09_RS12000 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9X4 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/1796616:A4V09_RS23105 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHD0 ^@ Function|||Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/1796616:A4V09_RS15855 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS16910 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC62 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/1796616:A4V09_RS11860 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID03 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/1796616:A4V09_RS15630 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFS4 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1796616:A4V09_RS15665 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDE1 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1796616:A4V09_RS18865 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID45 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS09165 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICF8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS20545 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIP1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/1796616:A4V09_RS14935 ^@ http://purl.uniprot.org/uniprot/A0A1C7IJX0 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/1796616:A4V09_RS15960 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS14245 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICP8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS01715 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4T6 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/1796616:A4V09_RS02115 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6U7 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1796616:A4V09_RS01210 ^@ http://purl.uniprot.org/uniprot/A0A1C7I665 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS05975 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6X1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS22285 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGY6 ^@ Function|||Similarity ^@ Belongs to the V-ATPase D subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1796616:A4V09_RS06330 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAY6 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/1796616:A4V09_RS04165 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5Q2 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/1796616:A4V09_RS05665 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8D7 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/1796616:A4V09_RS19015 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFH1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS22505 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEY3 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1796616:A4V09_RS20005 ^@ http://purl.uniprot.org/uniprot/A0A1C7II15 ^@ Function|||Similarity ^@ Belongs to the NanE family.|||Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P). http://togogenome.org/gene/1796616:A4V09_RS14745 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB24 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/1796616:A4V09_RS12520 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9Z0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS05915 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8R9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS07665 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7M9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS11975 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9N6 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.|||May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/1796616:A4V09_RS01440 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6R5 ^@ Function|||Similarity ^@ Belongs to the IolE/MocC family.|||Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol). http://togogenome.org/gene/1796616:A4V09_RS10015 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8P7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS05385 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6L4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS23180 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS13670 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICN9 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS01705 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6W2 ^@ Cofactor|||Similarity ^@ Belongs to the AlaDH/PNT family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/1796616:A4V09_RS08480 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9U7 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS06975 ^@ http://purl.uniprot.org/uniprot/A0A1C7I924 ^@ Similarity ^@ Belongs to the transpeptidase family. http://togogenome.org/gene/1796616:A4V09_RS11690 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICW5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS01395 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHG8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 2 family.|||Periplasm|||The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB). http://togogenome.org/gene/1796616:A4V09_RS02280 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6X7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1796616:A4V09_RS12115 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9Z2 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1796616:A4V09_RS02820 ^@ http://purl.uniprot.org/uniprot/A0A1C7I893 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS14665 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDE5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1796616:A4V09_RS07360 ^@ http://purl.uniprot.org/uniprot/A0A1C7I977 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/1796616:A4V09_RS20400 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS14975 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBD8 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/1796616:A4V09_RS08150 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7Z3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS14265 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAX9 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/1796616:A4V09_RS22900 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEZ9 ^@ Similarity ^@ Belongs to the barstar family. http://togogenome.org/gene/1796616:A4V09_RS18090 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICR5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/1796616:A4V09_RS12510 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC33 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1796616:A4V09_RS15295 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBK5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/1796616:A4V09_RS07870 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA25 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family. http://togogenome.org/gene/1796616:A4V09_RS13020 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDL1 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/1796616:A4V09_RS03835 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5K8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS02745 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5C0 ^@ Function ^@ May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/1796616:A4V09_RS17865 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICM2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS19995 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS19975 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDJ3 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1796616:A4V09_RS11200 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9B1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS07120 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9E6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS23545 ^@ http://purl.uniprot.org/uniprot/A0A1C7IJ34 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1796616:A4V09_RS20115 ^@ http://purl.uniprot.org/uniprot/A0A1C7II22 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/1796616:A4V09_RS03250 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7F3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS15350 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBL5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1796616:A4V09_RS09875 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8S8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1796616:A4V09_RS04400 ^@ http://purl.uniprot.org/uniprot/A0A1C7I944 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/1796616:A4V09_RS04210 ^@ http://purl.uniprot.org/uniprot/A0A1C7I626 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS11115 ^@ http://purl.uniprot.org/uniprot/A0A1C7I989 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/1796616:A4V09_RS05625 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6N7 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1796616:A4V09_RS21525 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEB0 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS15810 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBK9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/1796616:A4V09_RS16675 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC22 ^@ Function|||Similarity ^@ Belongs to the mannonate dehydratase family.|||Catalyzes the dehydration of D-mannonate. http://togogenome.org/gene/1796616:A4V09_RS15730 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBJ0 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1796616:A4V09_RS07760 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA02 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/1796616:A4V09_RS19825 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFC8 ^@ Function|||Similarity ^@ Belongs to the ROK (NagC/XylR) family.|||Transcriptional repressor of xylose-utilizing enzymes. http://togogenome.org/gene/1796616:A4V09_RS02605 ^@ http://purl.uniprot.org/uniprot/A0A1C7I569 ^@ Similarity ^@ Belongs to the ThrE exporter (TC 2.A.79) family. http://togogenome.org/gene/1796616:A4V09_RS07020 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7E8 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/1796616:A4V09_RS17235 ^@ http://purl.uniprot.org/uniprot/A0A1C7IED4 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/1796616:A4V09_RS21440 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEE7 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit.|||Homotetramer. http://togogenome.org/gene/1796616:A4V09_RS02455 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHZ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS04755 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7Y9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS10205 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAY1 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1796616:A4V09_RS18675 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1796616:A4V09_RS05480 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8S0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/1796616:A4V09_RS20500 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDV6 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/1796616:A4V09_RS07530 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7N2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/1796616:A4V09_RS15020 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDC3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS21485 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEC6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/1796616:A4V09_RS20595 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE66 ^@ Function|||Similarity ^@ Belongs to the ROK (NagC/XylR) family.|||Transcriptional repressor of xylose-utilizing enzymes. http://togogenome.org/gene/1796616:A4V09_RS15710 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBI9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1796616:A4V09_RS11625 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9K7 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1796616:A4V09_RS10055 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8W1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0053 family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS15455 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG50 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS09260 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8C6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS19515 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF76 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/1796616:A4V09_RS16835 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGD1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/1796616:A4V09_RS00260 ^@ http://purl.uniprot.org/uniprot/A0A1C7I676 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS04965 ^@ http://purl.uniprot.org/uniprot/A0A1C7II03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/1796616:A4V09_RS15545 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDC1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS04295 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9X5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS06235 ^@ http://purl.uniprot.org/uniprot/A0A1C7I719 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS15670 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEZ3 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1796616:A4V09_RS15985 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBN4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/1796616:A4V09_RS22190 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEM2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS05450 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8A3 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/1796616:A4V09_RS20465 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG19 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1796616:A4V09_RS18275 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF45 ^@ Similarity ^@ Belongs to the peptidase M20A family. http://togogenome.org/gene/1796616:A4V09_RS09495 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8G0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS23825 ^@ http://purl.uniprot.org/uniprot/A0A1C7IJZ3 ^@ Cofactor|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit. http://togogenome.org/gene/1796616:A4V09_RS17825 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEW3 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS00285 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHW5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpA family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/1796616:A4V09_RS11725 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9R6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/1796616:A4V09_RS04230 ^@ http://purl.uniprot.org/uniprot/A0A1C7I910 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/1796616:A4V09_RS08630 ^@ http://purl.uniprot.org/uniprot/A0A1C7I822 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1796616:A4V09_RS23555 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFH5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/1796616:A4V09_RS17310 ^@ http://purl.uniprot.org/uniprot/A0A1C7II39 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/1796616:A4V09_RS12080 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBL3 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/1796616:A4V09_RS16340 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS13745 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAK3 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/1796616:A4V09_RS16065 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBT0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/1796616:A4V09_RS05075 ^@ http://purl.uniprot.org/uniprot/A0A1C7I688 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/1796616:A4V09_RS00945 ^@ http://purl.uniprot.org/uniprot/A0A1C7I899 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1796616:A4V09_RS02725 ^@ http://purl.uniprot.org/uniprot/A0A1C7I585 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS22365 ^@ http://purl.uniprot.org/uniprot/A0A1C7IES9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS04325 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7S5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic Ku family.|||Homodimer. Interacts with LigD.|||With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. http://togogenome.org/gene/1796616:A4V09_RS05085 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHM7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS02540 ^@ http://purl.uniprot.org/uniprot/A0A1C7I500 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1796616:A4V09_RS16260 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC29 ^@ Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family. http://togogenome.org/gene/1796616:A4V09_RS16840 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEF0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 42 family. http://togogenome.org/gene/1796616:A4V09_RS10845 ^@ http://purl.uniprot.org/uniprot/A0A1C7I949 ^@ Similarity ^@ Belongs to the UPF0597 family. http://togogenome.org/gene/1796616:A4V09_RS08010 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAZ8 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1796616:A4V09_RS08715 ^@ http://purl.uniprot.org/uniprot/A0A1C7I846 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS06315 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA51 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial microcompartment|||Belongs to the EutC family.|||Binds between the large and small subunits.|||Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.|||The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards. http://togogenome.org/gene/1796616:A4V09_RS17990 ^@ http://purl.uniprot.org/uniprot/A0A1C7IER8 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1796616:A4V09_RS22110 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGW0 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/1796616:A4V09_RS03685 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5K6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS22835 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHC3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/1796616:A4V09_RS17045 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS09085 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8F4 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS05435 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6M7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS12765 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICG3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1796616:A4V09_RS13950 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEX4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L-fucose isomerase family.|||Converts the aldose L-fucose into the corresponding ketose L-fuculose.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS02665 ^@ http://purl.uniprot.org/uniprot/A0A1C7I947 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/1796616:A4V09_RS20950 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS14080 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAQ9 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/1796616:A4V09_RS17935 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS01550 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4L8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 42 family. http://togogenome.org/gene/1796616:A4V09_RS15735 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBL6 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1796616:A4V09_RS16560 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDT4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS12015 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBK4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS18100 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF17 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1796616:A4V09_RS07035 ^@ http://purl.uniprot.org/uniprot/A0A1C7I771 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0291 family.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS06630 ^@ http://purl.uniprot.org/uniprot/A0A1C7I951 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS05115 ^@ http://purl.uniprot.org/uniprot/A0A1C7I650 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/1796616:A4V09_RS21595 ^@ http://purl.uniprot.org/uniprot/A0A1C7II27 ^@ Similarity ^@ Belongs to the V-ATPase F subunit family. http://togogenome.org/gene/1796616:A4V09_RS13205 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC69 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.|||Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS21095 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE59 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/1796616:A4V09_RS04680 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8D4 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS13665 ^@ http://purl.uniprot.org/uniprot/A0A1C7IJV0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS04445 ^@ http://purl.uniprot.org/uniprot/A0A1C7I630 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS07055 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7E1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/1796616:A4V09_RS10805 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBI2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS00215 ^@ http://purl.uniprot.org/uniprot/A0A1C7I401 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS12400 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC12 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1796616:A4V09_RS03815 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7Z1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1796616:A4V09_RS16105 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDL8 ^@ Function|||Similarity ^@ Belongs to the anti-sigma-factor family.|||Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. http://togogenome.org/gene/1796616:A4V09_RS15845 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDY1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/1796616:A4V09_RS20150 ^@ http://purl.uniprot.org/uniprot/A0A1C7IH81 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/1796616:A4V09_RS06805 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8Y9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1796616:A4V09_RS22995 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFE2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS12750 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA23 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival. http://togogenome.org/gene/1796616:A4V09_RS08660 ^@ http://purl.uniprot.org/uniprot/A0A1C7I837 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS04745 ^@ http://purl.uniprot.org/uniprot/A0A1C7I680 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS21255 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG20 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/1796616:A4V09_RS02645 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6W6 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/1796616:A4V09_RS05445 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6B3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/1796616:A4V09_RS14605 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF97 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate. http://togogenome.org/gene/1796616:A4V09_RS18180 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICS1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1796616:A4V09_RS14650 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB05 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS23685 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFH0 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1796616:A4V09_RS17335 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFT2 ^@ Similarity ^@ Belongs to the transpeptidase family. http://togogenome.org/gene/1796616:A4V09_RS04815 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7Z8 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS23835 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHS2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1796616:A4V09_RS00925 ^@ http://purl.uniprot.org/uniprot/A0A1C7I622 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HPrK/P family.|||Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.|||Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.|||Homohexamer.|||The Walker A ATP-binding motif also binds Pi and PPi. http://togogenome.org/gene/1796616:A4V09_RS01380 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFP7 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS20125 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFV0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1796616:A4V09_RS09700 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBU9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/1796616:A4V09_RS05250 ^@ http://purl.uniprot.org/uniprot/A0A1C7IJJ2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/1796616:A4V09_RS23775 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHR4 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/1796616:A4V09_RS02425 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4Y1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS12445 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE47 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS14830 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB35 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/1796616:A4V09_RS15195 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBA2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1796616:A4V09_RS11750 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICX6 ^@ Similarity ^@ Belongs to the UPF0473 family. http://togogenome.org/gene/1796616:A4V09_RS15720 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDF1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1796616:A4V09_RS00920 ^@ http://purl.uniprot.org/uniprot/A0A1C7I448 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/1796616:A4V09_RS11620 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9I8 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1796616:A4V09_RS07030 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFY9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1796616:A4V09_RS16480 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/1796616:A4V09_RS07535 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7L0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS12590 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9Z5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Binds 1 Fe cation per subunit.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/1796616:A4V09_RS05765 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6P5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS19320 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHP1 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/1796616:A4V09_RS10280 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS11270 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9F9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1796616:A4V09_RS05775 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8F7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS06810 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAE0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS00485 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6B1 ^@ Similarity ^@ Belongs to the manganese catalase family. http://togogenome.org/gene/1796616:A4V09_RS09635 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8I1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS17340 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICA0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS03950 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5M8 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1796616:A4V09_RS15760 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBJ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/1796616:A4V09_RS20395 ^@ http://purl.uniprot.org/uniprot/A0A1C7II84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS01875 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4N0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS03625 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS06880 ^@ http://purl.uniprot.org/uniprot/A0A1C7I762 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS13760 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAJ0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1796616:A4V09_RS15660 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBI8 ^@ Similarity ^@ Belongs to the diacylglycerol/lipid kinase family. http://togogenome.org/gene/1796616:A4V09_RS16640 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBZ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/1796616:A4V09_RS13930 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE19 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/1796616:A4V09_RS08640 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC53 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1796616:A4V09_RS24015 ^@ http://purl.uniprot.org/uniprot/A0A1C7IL23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS08510 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAD5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1796616:A4V09_RS00425 ^@ http://purl.uniprot.org/uniprot/A0A1C7I449 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS12820 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICH4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS07825 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7T4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS05825 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6I5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ScpB family.|||Cytoplasm|||Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.|||Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. http://togogenome.org/gene/1796616:A4V09_RS12625 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA05 ^@ Similarity ^@ Belongs to the xanthine dehydrogenase family. http://togogenome.org/gene/1796616:A4V09_RS18695 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/1796616:A4V09_RS22250 ^@ http://purl.uniprot.org/uniprot/A0A1C7IES6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS03325 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5E4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS17545 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEI6 ^@ Similarity ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family. http://togogenome.org/gene/1796616:A4V09_RS01410 ^@ http://purl.uniprot.org/uniprot/A0A1C7I696 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS21380 ^@ http://purl.uniprot.org/uniprot/A0A1C7IED9 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS15570 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGC4 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/1796616:A4V09_RS03490 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5F1 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS05255 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAD4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/1796616:A4V09_RS18285 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS04155 ^@ http://purl.uniprot.org/uniprot/A0A1C7I617 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS20745 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGB9 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS15825 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF23 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1796616:A4V09_RS13750 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICG1 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/1796616:A4V09_RS02825 ^@ http://purl.uniprot.org/uniprot/A0A1C7I545 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1796616:A4V09_RS05790 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6M2 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/1796616:A4V09_RS13655 ^@ http://purl.uniprot.org/uniprot/A0A1C7IES7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS20335 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the P(II) protein family.|||Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS00065 ^@ http://purl.uniprot.org/uniprot/A0A1C7I3S6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS04555 ^@ http://purl.uniprot.org/uniprot/A0A1C7I821 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MobA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.|||Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. http://togogenome.org/gene/1796616:A4V09_RS14210 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/1796616:A4V09_RS13395 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICJ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1796616:A4V09_RS13285 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICQ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS00950 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS05945 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9W9 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/1796616:A4V09_RS09305 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8H7 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/1796616:A4V09_RS20155 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDP5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/1796616:A4V09_RS01580 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8K5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS11185 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBE6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the PyrK family.|||Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit.|||Heterotetramer of 2 PyrK and 2 PyrD type B subunits.|||Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). http://togogenome.org/gene/1796616:A4V09_RS08035 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9W1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS06050 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6R9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ApbE family.|||Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.|||Magnesium. Can also use manganese. http://togogenome.org/gene/1796616:A4V09_RS17730 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICJ5 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/1796616:A4V09_RS02040 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7U2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 32 family. http://togogenome.org/gene/1796616:A4V09_RS03910 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8V0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/1796616:A4V09_RS08310 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC03 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS17585 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGR4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS02850 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7G3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/1796616:A4V09_RS16405 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIG8 ^@ Cofactor|||Function|||Subunit ^@ Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.|||Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.|||Heterodimer of the IorA and IorB subunits. http://togogenome.org/gene/1796616:A4V09_RS12260 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9X7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS21575 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEN8 ^@ Function|||Similarity ^@ Belongs to the V-ATPase D subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1796616:A4V09_RS08055 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9M4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1796616:A4V09_RS09205 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBL4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS12545 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA27 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1796616:A4V09_RS16540 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE27 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/1796616:A4V09_RS08910 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8B7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/1796616:A4V09_RS08300 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7X6 ^@ Similarity ^@ Belongs to the type A lantibiotic family. http://togogenome.org/gene/1796616:A4V09_RS09295 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAT0 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/1796616:A4V09_RS19365 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS12280 ^@ http://purl.uniprot.org/uniprot/A0A1C7IKL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS03915 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5P8 ^@ Function|||Similarity ^@ Belongs to the RNase Y family.|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/1796616:A4V09_RS12530 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBU4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/1796616:A4V09_RS10975 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICI7 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs.|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/1796616:A4V09_RS09935 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB27 ^@ Activity Regulation|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. LacC subfamily.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/1796616:A4V09_RS03330 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5J1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LPG synthase family.|||Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS02705 ^@ http://purl.uniprot.org/uniprot/A0A1C7I869 ^@ Similarity ^@ Belongs to the transpeptidase family. http://togogenome.org/gene/1796616:A4V09_RS13175 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICP0 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1796616:A4V09_RS07090 ^@ http://purl.uniprot.org/uniprot/A0A1C7I942 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/1796616:A4V09_RS05245 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6H2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/1796616:A4V09_RS11985 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS09945 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8U0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS10695 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8Z4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS14685 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB26 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS17110 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEB5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/1796616:A4V09_RS10715 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAX4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS21800 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEF2 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/1796616:A4V09_RS15565 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBI7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/1796616:A4V09_RS02760 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6Y6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS20820 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFU5 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/1796616:A4V09_RS12800 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA32 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS18170 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICX8 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/1796616:A4V09_RS04150 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7V6 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/1796616:A4V09_RS04940 ^@ http://purl.uniprot.org/uniprot/A0A1C7I817 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS14925 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID15 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS07885 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7R3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS14110 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF04 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/1796616:A4V09_RS13375 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAD0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer and homodimer. http://togogenome.org/gene/1796616:A4V09_RS15755 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBT9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1796616:A4V09_RS23495 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFG5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/1796616:A4V09_RS03840 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7I8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/1796616:A4V09_RS19355 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGU4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS01950 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8R2 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1796616:A4V09_RS01545 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4R0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/1796616:A4V09_RS21590 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG77 ^@ Similarity ^@ Belongs to the V-ATPase E subunit family. http://togogenome.org/gene/1796616:A4V09_RS04960 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA85 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/1796616:A4V09_RS06555 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA90 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/1796616:A4V09_RS03930 ^@ http://purl.uniprot.org/uniprot/A0A1C7I809 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/1796616:A4V09_RS04790 ^@ http://purl.uniprot.org/uniprot/A0A1C7I860 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HAK/KUP transporter (TC 2.A.72) family.|||Cell membrane|||Membrane|||Transport of potassium into the cell. http://togogenome.org/gene/1796616:A4V09_RS20895 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIH8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS16050 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDK7 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS19315 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDB7 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/1796616:A4V09_RS02935 ^@ http://purl.uniprot.org/uniprot/A0A1C7I717 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1796616:A4V09_RS21325 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE97 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1796616:A4V09_RS13500 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS13915 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAM9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS09870 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8N0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS13225 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEJ7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/1796616:A4V09_RS07425 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7G2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1796616:A4V09_RS07630 ^@ http://purl.uniprot.org/uniprot/A0A1C7IKF0 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1796616:A4V09_RS10035 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8V8 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/1796616:A4V09_RS23010 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF69 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell membrane|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/1796616:A4V09_RS08535 ^@ http://purl.uniprot.org/uniprot/A0A1C7I819 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/1796616:A4V09_RS02585 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4Y5 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS22500 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEU8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS23315 ^@ http://purl.uniprot.org/uniprot/A0A1C7IH19 ^@ Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 67 family.|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS02080 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4P3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS06665 ^@ http://purl.uniprot.org/uniprot/A0A1C7I770 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS08240 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB49 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS23470 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS08965 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8D3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS20365 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDU0 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/1796616:A4V09_RS08955 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBH3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/1796616:A4V09_RS08130 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7X8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Cytoplasm|||Homodimer.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1796616:A4V09_RS23100 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHG1 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/1796616:A4V09_RS15285 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDP4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS19325 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFM2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS08520 ^@ http://purl.uniprot.org/uniprot/A0A1C7II83 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS06085 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6V4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS05150 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8L3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/1796616:A4V09_RS10305 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB96 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/1796616:A4V09_RS13305 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAD8 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1796616:A4V09_RS12620 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA77 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/1796616:A4V09_RS02750 ^@ http://purl.uniprot.org/uniprot/A0A1C7I578 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1796616:A4V09_RS11820 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9P8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS06165 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6Y8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1796616:A4V09_RS16280 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFB1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/1796616:A4V09_RS02395 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6Z2 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1796616:A4V09_RS20570 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDZ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.|||Homodimer.|||Involved in phosphonate degradation. http://togogenome.org/gene/1796616:A4V09_RS01565 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7L6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS11125 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDF3 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/1796616:A4V09_RS19870 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDI3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase. http://togogenome.org/gene/1796616:A4V09_RS01270 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7G5 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/1796616:A4V09_RS11685 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBE1 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS17850 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEE8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS02925 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5A5 ^@ Caution|||Function|||Similarity ^@ Belongs to the type IA topoisomerase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/1796616:A4V09_RS17685 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS06310 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8Q5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial microcompartment|||Belongs to the EutB family.|||Binds between the large and small subunits.|||Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.|||The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards. http://togogenome.org/gene/1796616:A4V09_RS16460 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBW8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS00265 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5Z0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1796616:A4V09_RS10520 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID49 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1796616:A4V09_RS15965 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS11865 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9L8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/1796616:A4V09_RS19425 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acyl-ACP thioesterase family.|||chloroplast http://togogenome.org/gene/1796616:A4V09_RS14580 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICV6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS09575 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8M5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1796616:A4V09_RS07505 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBK3 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS15850 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS18005 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICP3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS04945 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9D6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS08295 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7X6 ^@ Similarity ^@ Belongs to the type A lantibiotic family. http://togogenome.org/gene/1796616:A4V09_RS23060 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIA8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/1796616:A4V09_RS06925 ^@ http://purl.uniprot.org/uniprot/A0A1C7I911 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/1796616:A4V09_RS18935 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID27 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/1796616:A4V09_RS10405 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8X7 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1796616:A4V09_RS02860 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5E0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/1796616:A4V09_RS07450 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9V1 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/1796616:A4V09_RS02590 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6V5 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS06990 ^@ http://purl.uniprot.org/uniprot/A0A1C7I785 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsA/MreB family.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS17510 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFW2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS03260 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5H3 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Non-allosteric. http://togogenome.org/gene/1796616:A4V09_RS16580 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC23 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/1796616:A4V09_RS19240 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VirD4/TraG family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS05155 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8C3 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS11955 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9N5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1796616:A4V09_RS07680 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAT6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase. http://togogenome.org/gene/1796616:A4V09_RS05235 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9I6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/1796616:A4V09_RS14525 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICU6 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/1796616:A4V09_RS20955 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGA2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS13060 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS20160 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDR9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/1796616:A4V09_RS01905 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFY3 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/1796616:A4V09_RS16385 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDR2 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1796616:A4V09_RS17175 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS13055 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS14420 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID99 ^@ Similarity ^@ Belongs to the peptidase S14 family. http://togogenome.org/gene/1796616:A4V09_RS12390 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE37 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/1796616:A4V09_RS03795 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5M1 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/1796616:A4V09_RS04730 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8E5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YejK family.|||nucleoid http://togogenome.org/gene/1796616:A4V09_RS07650 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9P1 ^@ Function|||Similarity ^@ Belongs to the N-acylglucosamine 2-epimerase family.|||Belongs to the cellobiose 2-epimerase family.|||Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man). http://togogenome.org/gene/1796616:A4V09_RS03560 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5F9 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/1796616:A4V09_RS11190 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9G0 ^@ Similarity ^@ Belongs to the OMP decarboxylase family. Type 2 subfamily. http://togogenome.org/gene/1796616:A4V09_RS13130 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICE7 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/1796616:A4V09_RS22985 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHE5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS13885 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEW5 ^@ Function|||Similarity ^@ Belongs to the ROK (NagC/XylR) family.|||Transcriptional repressor of xylose-utilizing enzymes. http://togogenome.org/gene/1796616:A4V09_RS01435 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8H5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS15910 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDR5 ^@ Function|||Similarity ^@ Belongs to the RapZ-like family.|||Displays ATPase and GTPase activities. http://togogenome.org/gene/1796616:A4V09_RS15035 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB87 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS05840 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6N2 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/1796616:A4V09_RS10780 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICF7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS23380 ^@ http://purl.uniprot.org/uniprot/A0A1C7IJ06 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS02615 ^@ http://purl.uniprot.org/uniprot/A0A1C7I937 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/1796616:A4V09_RS20725 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHL0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/1796616:A4V09_RS06885 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7B4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS20560 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS15310 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID78 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS20680 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS05005 ^@ http://purl.uniprot.org/uniprot/A0A1C7I830 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1796616:A4V09_RS22280 ^@ http://purl.uniprot.org/uniprot/A0A1C7IH25 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. http://togogenome.org/gene/1796616:A4V09_RS15240 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBJ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.|||Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS16650 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS01780 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4Q8 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/1796616:A4V09_RS14985 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB78 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-C family. PolC subfamily.|||Cytoplasm|||Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/1796616:A4V09_RS15805 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBU7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1796616:A4V09_RS03385 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8L4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/1796616:A4V09_RS03130 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFN2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/1796616:A4V09_RS02690 ^@ http://purl.uniprot.org/uniprot/A0A1C7I506 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/1796616:A4V09_RS13835 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID01 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1796616:A4V09_RS20640 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG99 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1796616:A4V09_RS19780 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS03000 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8C4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/1796616:A4V09_RS04950 ^@ http://purl.uniprot.org/uniprot/A0A1C7I669 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/1796616:A4V09_RS02675 ^@ http://purl.uniprot.org/uniprot/A0A1C7I745 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/1796616:A4V09_RS04895 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA75 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/1796616:A4V09_RS16655 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEC5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1796616:A4V09_RS11830 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC00 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/1796616:A4V09_RS13650 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAL5 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/1796616:A4V09_RS19910 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFR7 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1796616:A4V09_RS00350 ^@ http://purl.uniprot.org/uniprot/A0A1C7I3X3 ^@ Function|||Similarity ^@ Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/1796616:A4V09_RS03165 ^@ http://purl.uniprot.org/uniprot/A0A1C7I769 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1796616:A4V09_RS01060 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4E0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS00125 ^@ http://purl.uniprot.org/uniprot/A0A1C7I977 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/1796616:A4V09_RS21390 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGM6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/1796616:A4V09_RS06905 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9A8 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1796616:A4V09_RS02030 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4N4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS20715 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDZ5 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/1796616:A4V09_RS04785 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8F5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1796616:A4V09_RS17405 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICE5 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/1796616:A4V09_RS20845 ^@ http://purl.uniprot.org/uniprot/A0A1C7IGD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS19915 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDU5 ^@ Cofactor ^@ Binds 2 magnesium ions per subunit. http://togogenome.org/gene/1796616:A4V09_RS12250 ^@ http://purl.uniprot.org/uniprot/A0A1C7ID71 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/1796616:A4V09_RS00970 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4D0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase Z family.|||Binds 2 Zn(2+) ions.|||Homodimer.|||Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. http://togogenome.org/gene/1796616:A4V09_RS20535 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDU3 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/1796616:A4V09_RS23510 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS16380 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBX3 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1796616:A4V09_RS21545 ^@ http://purl.uniprot.org/uniprot/A0A1C7II16 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/1796616:A4V09_RS13390 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICT0 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1796616:A4V09_RS06960 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7D8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS05040 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8J3 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/1796616:A4V09_RS05930 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6L0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/1796616:A4V09_RS08960 ^@ http://purl.uniprot.org/uniprot/A0A1C7I880 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS17260 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE39 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS04345 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5W8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS18385 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF64 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1796616:A4V09_RS03585 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9K3 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1796616:A4V09_RS10510 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFY1 ^@ Similarity|||Subunit ^@ Belongs to the glutaminase family.|||Homotetramer. http://togogenome.org/gene/1796616:A4V09_RS09410 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8K4 ^@ Similarity ^@ Belongs to the class I fructose-bisphosphate aldolase family. http://togogenome.org/gene/1796616:A4V09_RS01910 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4S9 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1796616:A4V09_RS10885 ^@ http://purl.uniprot.org/uniprot/A0A1C7I964 ^@ Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. http://togogenome.org/gene/1796616:A4V09_RS17830 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEN4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS14810 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB42 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS11225 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDH4 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/1796616:A4V09_RS21755 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS02740 ^@ http://purl.uniprot.org/uniprot/A0A1C7I754 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/1796616:A4V09_RS02340 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6Y7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the adenylate cyclase family. DacA/CdaA subfamily.|||Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably a homodimer. http://togogenome.org/gene/1796616:A4V09_RS08145 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9Y1 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/1796616:A4V09_RS23900 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHT2 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/1796616:A4V09_RS10025 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC05 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/1796616:A4V09_RS19525 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDC9 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1796616:A4V09_RS03700 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7X0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/1796616:A4V09_RS03740 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8S2 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/1796616:A4V09_RS09830 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8R8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.|||Cell membrane|||Membrane|||Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. http://togogenome.org/gene/1796616:A4V09_RS01495 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4P9 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/1796616:A4V09_RS23385 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF95 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS10470 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBC5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the methylaspartate mutase GlmS subunit family.|||Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).|||Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer. http://togogenome.org/gene/1796616:A4V09_RS04720 ^@ http://purl.uniprot.org/uniprot/A0A1C7I687 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/1796616:A4V09_RS14555 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDC5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS13765 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAN7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS12560 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC44 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS11240 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9G9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.|||Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.|||Cell membrane|||Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).|||Membrane http://togogenome.org/gene/1796616:A4V09_RS20455 ^@ http://purl.uniprot.org/uniprot/A0A1C7II94 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.|||Homodimer.|||Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate. http://togogenome.org/gene/1796616:A4V09_RS09185 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8C7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS22920 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF21 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1796616:A4V09_RS03400 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9I4 ^@ Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family. http://togogenome.org/gene/1796616:A4V09_RS15605 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBH9 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS05175 ^@ http://purl.uniprot.org/uniprot/A0A1C7I854 ^@ Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers). http://togogenome.org/gene/1796616:A4V09_RS23325 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF86 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/1796616:A4V09_RS15130 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDE3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/1796616:A4V09_RS16145 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBR3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS23475 ^@ http://purl.uniprot.org/uniprot/A0A1C7IH51 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/1796616:A4V09_RS17210 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFR1 ^@ Similarity ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. http://togogenome.org/gene/1796616:A4V09_RS22270 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEU2 ^@ Similarity ^@ Belongs to the V-ATPase F subunit family. http://togogenome.org/gene/1796616:A4V09_RS12090 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9Q5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS19070 ^@ http://purl.uniprot.org/uniprot/A0A1C7IFI2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS06125 ^@ http://purl.uniprot.org/uniprot/A0A1C7I8W5 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/1796616:A4V09_RS04080 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5X6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1796616:A4V09_RS02310 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4W4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/1796616:A4V09_RS22875 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF54 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS20920 ^@ http://purl.uniprot.org/uniprot/A0A1C7IE31 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/1796616:A4V09_RS11175 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDG5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS06955 ^@ http://purl.uniprot.org/uniprot/A0A1C7I9B6 ^@ Caution|||Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS15770 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDG0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1796616:A4V09_RS19345 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF48 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/1796616:A4V09_RS00290 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5R6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/1796616:A4V09_RS17370 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICJ9 ^@ Similarity ^@ Belongs to the GerABKA family. http://togogenome.org/gene/1796616:A4V09_RS02460 ^@ http://purl.uniprot.org/uniprot/A0A1C7I570 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS13725 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICY3 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/1796616:A4V09_RS03530 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHY1 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/1796616:A4V09_RS17845 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICL6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1796616:A4V09_RS07140 ^@ http://purl.uniprot.org/uniprot/A0A1C7I793 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1796616:A4V09_RS05065 ^@ http://purl.uniprot.org/uniprot/A0A1C7I840 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. GalK subfamily.|||Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS09375 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAA3 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/1796616:A4V09_RS20645 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG49 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS04390 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5T7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1796616:A4V09_RS19020 ^@ http://purl.uniprot.org/uniprot/A0A1C7I977 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/1796616:A4V09_RS01785 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4J3 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS19770 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHX3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase. http://togogenome.org/gene/1796616:A4V09_RS21280 ^@ http://purl.uniprot.org/uniprot/A0A1C7IIQ2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS17220 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICB7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1796616:A4V09_RS01370 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6G2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.|||Cell membrane|||Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.|||The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB). http://togogenome.org/gene/1796616:A4V09_RS21580 ^@ http://purl.uniprot.org/uniprot/A0A1C7IEC0 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. http://togogenome.org/gene/1796616:A4V09_RS19375 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHQ3 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS13160 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS01500 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4L2 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/1796616:A4V09_RS13605 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICW2 ^@ Similarity ^@ Belongs to the MecA family. http://togogenome.org/gene/1796616:A4V09_RS05530 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAI3 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/1796616:A4V09_RS03615 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7E7 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS16000 ^@ http://purl.uniprot.org/uniprot/A0A1C7IF56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS23230 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHF7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 27 family. http://togogenome.org/gene/1796616:A4V09_RS09990 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICU7 ^@ Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS12535 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS18240 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS20040 ^@ http://purl.uniprot.org/uniprot/A0A1C7IH66 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1796616:A4V09_RS02155 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4Y7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class U subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. http://togogenome.org/gene/1796616:A4V09_RS10255 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAZ0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphopentomutase family.|||Binds 1 or 2 manganese ions.|||Cytoplasm|||Phosphotransfer between the C1 and C5 carbon atoms of pentose. http://togogenome.org/gene/1796616:A4V09_RS11655 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDR0 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/1796616:A4V09_RS14920 ^@ http://purl.uniprot.org/uniprot/A0A1C7IB63 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1796616:A4V09_RS03310 ^@ http://purl.uniprot.org/uniprot/A0A1C7I5B9 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/1796616:A4V09_RS06970 ^@ http://purl.uniprot.org/uniprot/A0A1C7I763 ^@ Function|||Similarity ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily. http://togogenome.org/gene/1796616:A4V09_RS00435 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6A3 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/1796616:A4V09_RS13190 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAA4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS19800 ^@ http://purl.uniprot.org/uniprot/A0A1C7IDG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1796616:A4V09_RS20180 ^@ http://purl.uniprot.org/uniprot/A0A1C7IG07 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1796616:A4V09_RS12925 ^@ http://purl.uniprot.org/uniprot/A0A1C7IA99 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1796616:A4V09_RS02180 ^@ http://purl.uniprot.org/uniprot/A0A1C7I4X8 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1796616:A4V09_RS09035 ^@ http://purl.uniprot.org/uniprot/A0A1C7IAP0 ^@ Similarity ^@ Belongs to the plasmid replication initiation factor family. http://togogenome.org/gene/1796616:A4V09_RS03990 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7S2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1796616:A4V09_RS12790 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBZ7 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/1796616:A4V09_RS15980 ^@ http://purl.uniprot.org/uniprot/A0A1C7IBX9 ^@ Similarity ^@ Belongs to the peptidase M17 family. http://togogenome.org/gene/1796616:A4V09_RS17215 ^@ http://purl.uniprot.org/uniprot/A0A1C7IC83 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/1796616:A4V09_RS11925 ^@ http://purl.uniprot.org/uniprot/A0A1C7IHW0 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/1796616:A4V09_RS03705 ^@ http://purl.uniprot.org/uniprot/A0A1C7I7M6 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1796616:A4V09_RS05740 ^@ http://purl.uniprot.org/uniprot/A0A1C7I6R1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1796616:A4V09_RS17455 ^@ http://purl.uniprot.org/uniprot/A0A1C7ICC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane