http://togogenome.org/gene/1775880:D3791_RS06205 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHI6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1775880:D3791_RS15365 ^@ http://purl.uniprot.org/uniprot/A0A6H0SM21 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1775880:D3791_RS00865 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIH3 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS00495 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGR1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/1775880:D3791_RS01235 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIQ2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1775880:D3791_RS05630 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKZ1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1775880:D3791_RS03365 ^@ http://purl.uniprot.org/uniprot/A0A6H0SG13 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/1775880:D3791_RS01095 ^@ http://purl.uniprot.org/uniprot/A0A6H0SH24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane http://togogenome.org/gene/1775880:D3791_RS13055 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1775880:D3791_RS15615 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLT3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/1775880:D3791_RS03120 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFA9 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1775880:D3791_RS09590 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJJ3 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1775880:D3791_RS15695 ^@ http://purl.uniprot.org/uniprot/A0A6H0SPR5 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1775880:D3791_RS13705 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLM4 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/1775880:D3791_RS09295 ^@ http://purl.uniprot.org/uniprot/A0A6H0SN42 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1775880:D3791_RS00505 ^@ http://purl.uniprot.org/uniprot/A0A6H0SDY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VKOR family.|||Membrane http://togogenome.org/gene/1775880:D3791_RS16195 ^@ http://purl.uniprot.org/uniprot/A0A6H0SM33 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.|||Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.|||The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group. http://togogenome.org/gene/1775880:D3791_RS02845 ^@ http://purl.uniprot.org/uniprot/A0A6H0SG55 ^@ Subcellular Location Annotation|||Subunit ^@ Cell inner membrane|||Homodimer.|||Membrane http://togogenome.org/gene/1775880:D3791_RS08260 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLA1 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1775880:D3791_RS02560 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJD4 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/1775880:D3791_RS08130 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKK6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/1775880:D3791_RS08595 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/1775880:D3791_RS02930 ^@ http://purl.uniprot.org/uniprot/A0A6H0SG96 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1775880:D3791_RS14135 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLX9 ^@ Similarity ^@ Belongs to the class-II DAHP synthase family. http://togogenome.org/gene/1775880:D3791_RS04195 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJ72 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/1775880:D3791_RS01855 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1775880:D3791_RS16190 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLB3 ^@ Caution|||Domain|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic ubiquitin-like protein family.|||Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.|||Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.|||The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome. http://togogenome.org/gene/1775880:D3791_RS05835 ^@ http://purl.uniprot.org/uniprot/A0A6H0SK21 ^@ Function|||Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.|||Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate. http://togogenome.org/gene/1775880:D3791_RS02915 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFT4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1775880:D3791_RS01695 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIY2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS13395 ^@ http://purl.uniprot.org/uniprot/A0A6H0SL09 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS01355 ^@ http://purl.uniprot.org/uniprot/A0A6H0SH62 ^@ Function|||Subcellular Location Annotation ^@ Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.|||Membrane http://togogenome.org/gene/1775880:D3791_RS16245 ^@ http://purl.uniprot.org/uniprot/A0A6H0SM47 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase-binding protein RbpA family.|||Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.|||Forms a complex with the RNAP catalytic core and with free principal sigma factors.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS05685 ^@ http://purl.uniprot.org/uniprot/A0A6H0SL01 ^@ Similarity ^@ Belongs to the DSD1 family. http://togogenome.org/gene/1775880:D3791_RS10805 ^@ http://purl.uniprot.org/uniprot/A0A6H0SK62 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/1775880:D3791_RS05450 ^@ http://purl.uniprot.org/uniprot/A0A6H0SG43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1775880:D3791_RS11310 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJI0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/1775880:D3791_RS15530 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMN2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/1775880:D3791_RS13645 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNN9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/1775880:D3791_RS05475 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKW1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/1775880:D3791_RS16630 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/1775880:D3791_RS14380 ^@ http://purl.uniprot.org/uniprot/A0A6H0SP21 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/1775880:D3791_RS05300 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJS7 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1775880:D3791_RS04165 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIY5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1775880:D3791_RS08310 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLB0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/1775880:D3791_RS08865 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLC6 ^@ Similarity|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Homohexamer. The oligomerization is ATP-dependent. http://togogenome.org/gene/1775880:D3791_RS13100 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJS8 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1775880:D3791_RS02040 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHV1 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/1775880:D3791_RS14630 ^@ http://purl.uniprot.org/uniprot/A0A6H0SPF9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS02130 ^@ http://purl.uniprot.org/uniprot/A0A6H0SES9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/1775880:D3791_RS12075 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNN1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.|||Belongs to the MshB deacetylase family. Mca subfamily.|||Binds 1 zinc ion per subunit.|||Monomer. http://togogenome.org/gene/1775880:D3791_RS00445 ^@ http://purl.uniprot.org/uniprot/A0A6H0SDX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/1775880:D3791_RS12810 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKB0 ^@ Caution|||Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS05325 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1775880:D3791_RS16325 ^@ http://purl.uniprot.org/uniprot/A0A6H0SN21 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rieske iron-sulfur protein family.|||Cell membrane|||Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.|||Membrane http://togogenome.org/gene/1775880:D3791_RS01930 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHG8 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/1775880:D3791_RS07375 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1775880:D3791_RS00655 ^@ http://purl.uniprot.org/uniprot/A0A6H0SDP3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1775880:D3791_RS03975 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJ38 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/1775880:D3791_RS04820 ^@ http://purl.uniprot.org/uniprot/A0A6H0SH65 ^@ Similarity ^@ Belongs to the HIBADH-related family. http://togogenome.org/gene/1775880:D3791_RS12540 ^@ http://purl.uniprot.org/uniprot/A0A6H0SK57 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1775880:D3791_RS13300 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNH5 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1775880:D3791_RS15765 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLZ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS01690 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFM7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1775880:D3791_RS00525 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIB4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/1775880:D3791_RS15790 ^@ http://purl.uniprot.org/uniprot/A0A6H0SL50 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS00925 ^@ http://purl.uniprot.org/uniprot/A0A6H0SH94 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1775880:D3791_RS03115 ^@ http://purl.uniprot.org/uniprot/A0A6H0SEY6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1775880:D3791_RS10540 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNL0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1775880:D3791_RS01595 ^@ http://purl.uniprot.org/uniprot/A0A6H0SEW0 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1775880:D3791_RS05270 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNC4 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/1775880:D3791_RS13260 ^@ http://purl.uniprot.org/uniprot/A0A6H0SN17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1775880:D3791_RS11495 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNV7 ^@ Similarity ^@ Belongs to the transglycosylase family. Rpf subfamily. http://togogenome.org/gene/1775880:D3791_RS14905 ^@ http://purl.uniprot.org/uniprot/A0A6H0SQM6 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/1775880:D3791_RS01925 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFQ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ETF alpha-subunit/FixB family.|||Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/1775880:D3791_RS01580 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHV9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/1775880:D3791_RS05480 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGW5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1775880:D3791_RS07800 ^@ http://purl.uniprot.org/uniprot/A0A6H0SH97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/1775880:D3791_RS12015 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMV2 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1775880:D3791_RS00275 ^@ http://purl.uniprot.org/uniprot/A0A6H0SH79 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/1775880:D3791_RS05540 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHJ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS15600 ^@ http://purl.uniprot.org/uniprot/A0A6H0SML1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/1775880:D3791_RS02160 ^@ http://purl.uniprot.org/uniprot/A0A6H0SF59 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/1775880:D3791_RS00810 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIG3 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/1775880:D3791_RS03325 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFR9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. http://togogenome.org/gene/1775880:D3791_RS13810 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNB4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.|||Homotetramer.|||Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP. http://togogenome.org/gene/1775880:D3791_RS00830 ^@ http://purl.uniprot.org/uniprot/A0A6H0SF66 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS15900 ^@ http://purl.uniprot.org/uniprot/A0A6H0SL69 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1775880:D3791_RS14565 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLM6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/1775880:D3791_RS09335 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMT2 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/1775880:D3791_RS03170 ^@ http://purl.uniprot.org/uniprot/A0A6H0SEZ6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS11905 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKP8 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/1775880:D3791_RS06300 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJQ5 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/1775880:D3791_RS00390 ^@ http://purl.uniprot.org/uniprot/A0A6H0SH98 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1775880:D3791_RS03870 ^@ http://purl.uniprot.org/uniprot/A0A6H0SG24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/1775880:D3791_RS03405 ^@ http://purl.uniprot.org/uniprot/A0A6H0SF34 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1775880:D3791_RS15310 ^@ http://purl.uniprot.org/uniprot/A0A6H0SPS7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1775880:D3791_RS01635 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFL5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/1775880:D3791_RS03070 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFW6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1775880:D3791_RS07665 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLZ7 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/1775880:D3791_RS00285 ^@ http://purl.uniprot.org/uniprot/A0A6H0SI73 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Electron transport system for the ribonucleotide reductase system NrdEF. http://togogenome.org/gene/1775880:D3791_RS05535 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJP9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS12290 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKW9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS08930 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJ85 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1775880:D3791_RS09640 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJK3 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/1775880:D3791_RS15190 ^@ http://purl.uniprot.org/uniprot/A0A6H0SQS6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1775880:D3791_RS16500 ^@ http://purl.uniprot.org/uniprot/A0A6H0SQ57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/1775880:D3791_RS01300 ^@ http://purl.uniprot.org/uniprot/A0A6H0SE01 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/1775880:D3791_RS12840 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKI1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS03360 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFE7 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/1775880:D3791_RS09510 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1775880:D3791_RS12005 ^@ http://purl.uniprot.org/uniprot/A0A6H0SP45 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/1775880:D3791_RS12955 ^@ http://purl.uniprot.org/uniprot/A0A6H0SPL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1775880:D3791_RS09575 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMX6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1775880:D3791_RS03055 ^@ http://purl.uniprot.org/uniprot/A0A6H0SI24 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1775880:D3791_RS12705 ^@ http://purl.uniprot.org/uniprot/A0A6H0SQS1 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1775880:D3791_RS15620 ^@ http://purl.uniprot.org/uniprot/A0A6H0SM71 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/1775880:D3791_RS04025 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGE1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS04475 ^@ http://purl.uniprot.org/uniprot/A0A6H0SH28 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS13930 ^@ http://purl.uniprot.org/uniprot/A0A6H0SL22 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS08745 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHQ7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS05080 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHE1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS01680 ^@ http://purl.uniprot.org/uniprot/A0A6H0SF63 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/1775880:D3791_RS02625 ^@ http://purl.uniprot.org/uniprot/A0A6H0SI58 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/1775880:D3791_RS12670 ^@ http://purl.uniprot.org/uniprot/A0A6H0SN67 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1775880:D3791_RS01620 ^@ http://purl.uniprot.org/uniprot/A0A6H0SEJ6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/1775880:D3791_RS12135 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKU0 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/1775880:D3791_RS15250 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLJ8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1775880:D3791_RS00690 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHE5 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/1775880:D3791_RS13380 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJX9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 68 family. http://togogenome.org/gene/1775880:D3791_RS03785 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFA4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/1775880:D3791_RS15175 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLZ2 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1775880:D3791_RS04060 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIJ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Catalyzes the reversible hydration of fumarate to (S)-malate.|||Homodimer. http://togogenome.org/gene/1775880:D3791_RS08280 ^@ http://purl.uniprot.org/uniprot/A0A6H0SL27 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/1775880:D3791_RS07915 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1775880:D3791_RS02910 ^@ http://purl.uniprot.org/uniprot/A0A6H0SF71 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/1775880:D3791_RS01650 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHN0 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1775880:D3791_RS00490 ^@ http://purl.uniprot.org/uniprot/A0A6H0SF05 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1775880:D3791_RS04185 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1775880:D3791_RS03045 ^@ http://purl.uniprot.org/uniprot/A0A6H0SID8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1775880:D3791_RS10530 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNE7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/1775880:D3791_RS13435 ^@ http://purl.uniprot.org/uniprot/A0A6H0SN48 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/1775880:D3791_RS04145 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJ64 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1775880:D3791_RS13450 ^@ http://purl.uniprot.org/uniprot/A0A6H0SL16 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Binds 1 Fe cation per subunit.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/1775880:D3791_RS15780 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMN9 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/1775880:D3791_RS03535 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFV8 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/1775880:D3791_RS03615 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFJ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS00780 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/1775880:D3791_RS04385 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGC1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS02705 ^@ http://purl.uniprot.org/uniprot/A0A6H0SG59 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/1775880:D3791_RS05505 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGI0 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/1775880:D3791_RS15470 ^@ http://purl.uniprot.org/uniprot/A0A6H0SPV5 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/1775880:D3791_RS02880 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJJ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1775880:D3791_RS02975 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIL3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/1775880:D3791_RS15775 ^@ http://purl.uniprot.org/uniprot/A0A6H0SPS4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1775880:D3791_RS13115 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNN7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/1775880:D3791_RS02190 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFF2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.|||Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.|||Cytoplasm|||Homotrimer. http://togogenome.org/gene/1775880:D3791_RS09260 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMS1 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/1775880:D3791_RS03420 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1775880:D3791_RS09935 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIU4 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine. http://togogenome.org/gene/1775880:D3791_RS14665 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1775880:D3791_RS12915 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMV6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS00930 ^@ http://purl.uniprot.org/uniprot/A0A6H0SF84 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/1775880:D3791_RS06210 ^@ http://purl.uniprot.org/uniprot/A0A6H0SK91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1775880:D3791_RS07005 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKL7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1775880:D3791_RS02210 ^@ http://purl.uniprot.org/uniprot/A0A6H0SQJ0 ^@ Cofactor|||Function ^@ Binds 1 [3Fe-4S] cluster.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1775880:D3791_RS05660 ^@ http://purl.uniprot.org/uniprot/A0A6H0SG83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1775880:D3791_RS07090 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKH4 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1775880:D3791_RS11970 ^@ http://purl.uniprot.org/uniprot/A0A6H0SME1 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/1775880:D3791_RS08710 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJ91 ^@ Similarity ^@ Belongs to the peptidase C15 family. http://togogenome.org/gene/1775880:D3791_RS05460 ^@ http://purl.uniprot.org/uniprot/A0A6H0SH51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1775880:D3791_RS16015 ^@ http://purl.uniprot.org/uniprot/A0A6H0SPE3 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1775880:D3791_RS04190 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1775880:D3791_RS07975 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIC2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1775880:D3791_RS12330 ^@ http://purl.uniprot.org/uniprot/A0A6H0SPA7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. http://togogenome.org/gene/1775880:D3791_RS02970 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFU5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1775880:D3791_RS02950 ^@ http://purl.uniprot.org/uniprot/A0A6H0SG75 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1775880:D3791_RS08610 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIF9 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS03180 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFY4 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity ^@ Belongs to the nitrobindin family.|||Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.|||Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.|||Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS11255 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJX8 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. http://togogenome.org/gene/1775880:D3791_RS00165 ^@ http://purl.uniprot.org/uniprot/A0A6H0SDS7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/1775880:D3791_RS04430 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1775880:D3791_RS00645 ^@ http://purl.uniprot.org/uniprot/A0A6H0SF39 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1775880:D3791_RS16615 ^@ http://purl.uniprot.org/uniprot/A0A6H0SPP9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/1775880:D3791_RS10800 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMA9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/1775880:D3791_RS03565 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFI7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/1775880:D3791_RS12000 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1775880:D3791_RS04445 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGZ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS03075 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIN4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1775880:D3791_RS01365 ^@ http://purl.uniprot.org/uniprot/A0A6H0SEE9 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 2 subfamily.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS00030 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/1775880:D3791_RS03080 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGC5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1775880:D3791_RS14405 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLI9 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/1775880:D3791_RS11195 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJW9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ThrE exporter (TC 2.A.79) family.|||Membrane http://togogenome.org/gene/1775880:D3791_RS12940 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNL1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1775880:D3791_RS13320 ^@ http://purl.uniprot.org/uniprot/A0A6H0SQB0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS01630 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHW9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1775880:D3791_RS07525 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKV5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS02985 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJL5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1775880:D3791_RS03010 ^@ http://purl.uniprot.org/uniprot/A0A6H0SEW5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1775880:D3791_RS01750 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIZ3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/1775880:D3791_RS07595 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKW5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1775880:D3791_RS12155 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKD8 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/1775880:D3791_RS14160 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNH3 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1775880:D3791_RS03125 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFX6 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/1775880:D3791_RS12110 ^@ http://purl.uniprot.org/uniprot/A0A6H0SN55 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1775880:D3791_RS13750 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNR1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1775880:D3791_RS07245 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKK3 ^@ Similarity ^@ Belongs to the PrpF family. http://togogenome.org/gene/1775880:D3791_RS03650 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIP2 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/1775880:D3791_RS13680 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNY2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/1775880:D3791_RS09660 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJ60 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1775880:D3791_RS02980 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGA6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1775880:D3791_RS04080 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGF1 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1775880:D3791_RS01160 ^@ http://purl.uniprot.org/uniprot/A0A6H0SDX8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1775880:D3791_RS01675 ^@ http://purl.uniprot.org/uniprot/A0A6H0SEK3 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/1775880:D3791_RS09040 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIM9 ^@ Similarity ^@ Belongs to the CsoR family. http://togogenome.org/gene/1775880:D3791_RS03090 ^@ http://purl.uniprot.org/uniprot/A0A6H0SRM4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1775880:D3791_RS03725 ^@ http://purl.uniprot.org/uniprot/A0A6H0SND2 ^@ Function|||Similarity ^@ Belongs to the TrhO family.|||Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs. http://togogenome.org/gene/1775880:D3791_RS01875 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFP8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS03065 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFA0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1775880:D3791_RS09755 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJM4 ^@ Similarity ^@ Belongs to the DszC flavin monooxygenase family. http://togogenome.org/gene/1775880:D3791_RS13245 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKQ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1775880:D3791_RS16605 ^@ http://purl.uniprot.org/uniprot/A0A6H0SQ76 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS03415 ^@ http://purl.uniprot.org/uniprot/A0A6H0SG31 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1775880:D3791_RS03165 ^@ http://purl.uniprot.org/uniprot/A0A6H0SI43 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS01505 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1775880:D3791_RS04360 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJA5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1775880:D3791_RS08530 ^@ http://purl.uniprot.org/uniprot/A0A6H0SI47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1775880:D3791_RS03690 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIY8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1775880:D3791_RS10200 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLK5 ^@ Function ^@ Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. http://togogenome.org/gene/1775880:D3791_RS08500 ^@ http://purl.uniprot.org/uniprot/A0A6H0SME4 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1775880:D3791_RS07940 ^@ http://purl.uniprot.org/uniprot/A0A6H0SM45 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.|||Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).|||Homotetramer. http://togogenome.org/gene/1775880:D3791_RS13720 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKS7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/1775880:D3791_RS02945 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIB5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1775880:D3791_RS16150 ^@ http://purl.uniprot.org/uniprot/A0A6H0SQ73 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/1775880:D3791_RS16370 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMK5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/1775880:D3791_RS15245 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/1775880:D3791_RS10465 ^@ http://purl.uniprot.org/uniprot/A0A6H0SND8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/1775880:D3791_RS04045 ^@ http://purl.uniprot.org/uniprot/A0A6H0SG54 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS14460 ^@ http://purl.uniprot.org/uniprot/A0A6H0SPC9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1775880:D3791_RS13880 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKV7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1775880:D3791_RS09250 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/1775880:D3791_RS02900 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHY9 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1775880:D3791_RS06325 ^@ http://purl.uniprot.org/uniprot/A0A6H0SI19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.|||Membrane http://togogenome.org/gene/1775880:D3791_RS01130 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFC6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/1775880:D3791_RS00940 ^@ http://purl.uniprot.org/uniprot/A0A6H0SDT9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/1775880:D3791_RS02025 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1775880:D3791_RS14385 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLZ0 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/1775880:D3791_RS06980 ^@ http://purl.uniprot.org/uniprot/A0A6H0SK12 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1775880:D3791_RS01190 ^@ http://purl.uniprot.org/uniprot/A0A6H0SEN8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/1775880:D3791_RS12855 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMU7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.|||Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1775880:D3791_RS00455 ^@ http://purl.uniprot.org/uniprot/A0A6H0SEJ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/1775880:D3791_RS06405 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJS5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS12430 ^@ http://purl.uniprot.org/uniprot/A0A6H0SK38 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1775880:D3791_RS09855 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLU1 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1775880:D3791_RS08315 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJ22 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/1775880:D3791_RS03595 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIN1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MenA family. Type 1 subfamily.|||Cell membrane|||Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).|||Membrane http://togogenome.org/gene/1775880:D3791_RS11285 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMH6 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1775880:D3791_RS16315 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1775880:D3791_RS14455 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLJ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/1775880:D3791_RS05405 ^@ http://purl.uniprot.org/uniprot/A0A6H0SH43 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/1775880:D3791_RS15655 ^@ http://purl.uniprot.org/uniprot/A0A6H0SP84 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/1775880:D3791_RS05175 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFZ7 ^@ Function ^@ TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. http://togogenome.org/gene/1775880:D3791_RS01985 ^@ http://purl.uniprot.org/uniprot/A0A6H0SF32 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1775880:D3791_RS12860 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJP4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/1775880:D3791_RS16560 ^@ http://purl.uniprot.org/uniprot/A0A6H0SN34 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/1775880:D3791_RS02600 ^@ http://purl.uniprot.org/uniprot/A0A6H0SID6 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1775880:D3791_RS00385 ^@ http://purl.uniprot.org/uniprot/A0A6H0SEI8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease beta subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1775880:D3791_RS16575 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMB3 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/1775880:D3791_RS08490 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLE0 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1775880:D3791_RS16320 ^@ http://purl.uniprot.org/uniprot/A0A6H0SQA5 ^@ Caution|||PTM|||Subcellular Location Annotation|||Subunit ^@ Binds 2 heme c groups covalently per subunit.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit. http://togogenome.org/gene/1775880:D3791_RS08135 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHF6 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS02200 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFW3 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1775880:D3791_RS16005 ^@ http://purl.uniprot.org/uniprot/A0A6H0SPW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1775880:D3791_RS12760 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNI1 ^@ Similarity ^@ Belongs to the dGTPase family. Type 2 subfamily. http://togogenome.org/gene/1775880:D3791_RS01615 ^@ http://purl.uniprot.org/uniprot/A0A6H0SE62 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1775880:D3791_RS14985 ^@ http://purl.uniprot.org/uniprot/A0A6H0SQN7 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1775880:D3791_RS13190 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNF5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/1775880:D3791_RS11260 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMQ7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DtxR/MntR family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1775880:D3791_RS00715 ^@ http://purl.uniprot.org/uniprot/A0A6H0SF48 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/1775880:D3791_RS12390 ^@ http://purl.uniprot.org/uniprot/A0A6H0SPB6 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1775880:D3791_RS15315 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNT7 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1775880:D3791_RS00485 ^@ http://purl.uniprot.org/uniprot/A0A6H0SH18 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1775880:D3791_RS16250 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMI5 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/1775880:D3791_RS12230 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKV9 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1775880:D3791_RS16205 ^@ http://purl.uniprot.org/uniprot/A0A6H0SQ84 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1775880:D3791_RS01575 ^@ http://purl.uniprot.org/uniprot/A0A6H0SF42 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/1775880:D3791_RS04150 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGW6 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1775880:D3791_RS02695 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFP0 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/1775880:D3791_RS08720 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIH8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/1775880:D3791_RS04700 ^@ http://purl.uniprot.org/uniprot/A0A6H0SH69 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/1775880:D3791_RS12435 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKI7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS08380 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLB9 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1775880:D3791_RS03035 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJM1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1775880:D3791_RS09595 ^@ http://purl.uniprot.org/uniprot/A0A6H0SL96 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/1775880:D3791_RS13775 ^@ http://purl.uniprot.org/uniprot/A0A6H0SL81 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1775880:D3791_RS16395 ^@ http://purl.uniprot.org/uniprot/A0A6H0SQ40 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/1775880:D3791_RS03050 ^@ http://purl.uniprot.org/uniprot/A0A6H0SG95 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/1775880:D3791_RS12950 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLC1 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS12295 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMK0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/1775880:D3791_RS11270 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKG4 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1775880:D3791_RS00280 ^@ http://purl.uniprot.org/uniprot/A0A6H0SEY0 ^@ Function|||Similarity ^@ Belongs to the NrdI family.|||Probably involved in ribonucleotide reductase function. http://togogenome.org/gene/1775880:D3791_RS13995 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNE3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1775880:D3791_RS14845 ^@ http://purl.uniprot.org/uniprot/A0A6H0SPJ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS01305 ^@ http://purl.uniprot.org/uniprot/A0A6H0SED9 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/1775880:D3791_RS12060 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKW0 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/1775880:D3791_RS02035 ^@ http://purl.uniprot.org/uniprot/A0A6H0SF40 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1775880:D3791_RS02960 ^@ http://purl.uniprot.org/uniprot/A0A6H0SEV5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1775880:D3791_RS14230 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLF3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrcB (TC 9.B.71) family.|||Cell membrane|||Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane http://togogenome.org/gene/1775880:D3791_RS05205 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGR6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1775880:D3791_RS10215 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJF5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/1775880:D3791_RS14195 ^@ http://purl.uniprot.org/uniprot/A0A6H0SL74 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/1775880:D3791_RS09860 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJP0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1775880:D3791_RS09850 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJ16 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1775880:D3791_RS06330 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLC5 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/1775880:D3791_RS02180 ^@ http://purl.uniprot.org/uniprot/A0A6H0SEG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1775880:D3791_RS16580 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMP1 ^@ Function|||Similarity ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. http://togogenome.org/gene/1775880:D3791_RS03935 ^@ http://purl.uniprot.org/uniprot/A0A6H0SK37 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/1775880:D3791_RS12335 ^@ http://purl.uniprot.org/uniprot/A0A6H0SK94 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/1775880:D3791_RS11025 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKD4 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/1775880:D3791_RS05305 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHI3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1775880:D3791_RS04635 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJF7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS14145 ^@ http://purl.uniprot.org/uniprot/A0A6H0SL63 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1775880:D3791_RS03015 ^@ http://purl.uniprot.org/uniprot/A0A6H0SF90 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1775880:D3791_RS04170 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGU3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1775880:D3791_RS01740 ^@ http://purl.uniprot.org/uniprot/A0A6H0SRK3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/1775880:D3791_RS07220 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1775880:D3791_RS00570 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHC7 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/1775880:D3791_RS01670 ^@ http://purl.uniprot.org/uniprot/A0A6H0SE72 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/1775880:D3791_RS10535 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJD2 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/1775880:D3791_RS05285 ^@ http://purl.uniprot.org/uniprot/A0A6H0SG16 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1775880:D3791_RS00575 ^@ http://purl.uniprot.org/uniprot/A0A6H0SF27 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1775880:D3791_RS02175 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1775880:D3791_RS09995 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIB7 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/1775880:D3791_RS09750 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NlpA lipoprotein family.|||Membrane http://togogenome.org/gene/1775880:D3791_RS13060 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1775880:D3791_RS03585 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJX2 ^@ Caution|||Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.|||Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS07755 ^@ http://purl.uniprot.org/uniprot/A0A6H0SI78 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS04935 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJE1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS04365 ^@ http://purl.uniprot.org/uniprot/A0A6H0SH07 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1775880:D3791_RS02925 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNB6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1775880:D3791_RS03085 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJN1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1775880:D3791_RS07070 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLP9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1775880:D3791_RS15850 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMB4 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1775880:D3791_RS14335 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNK4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS03665 ^@ http://purl.uniprot.org/uniprot/A0A6H0SF83 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/1775880:D3791_RS06305 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGK5 ^@ Similarity ^@ Belongs to the CsoR family. http://togogenome.org/gene/1775880:D3791_RS00270 ^@ http://purl.uniprot.org/uniprot/A0A6H0SEG8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1775880:D3791_RS02905 ^@ http://purl.uniprot.org/uniprot/A0A6H0SEU4 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1775880:D3791_RS14400 ^@ http://purl.uniprot.org/uniprot/A0A6H0SL43 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/1775880:D3791_RS14255 ^@ http://purl.uniprot.org/uniprot/A0A6H0SR27 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1775880:D3791_RS12395 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKA5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS15745 ^@ http://purl.uniprot.org/uniprot/A0A6H0SQ04 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/1775880:D3791_RS14190 ^@ http://purl.uniprot.org/uniprot/A0A6H0SQ95 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF2.|||Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. http://togogenome.org/gene/1775880:D3791_RS14475 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLC2 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/1775880:D3791_RS12130 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMX0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/1775880:D3791_RS03640 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJY3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/1775880:D3791_RS11225 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMG7 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/1775880:D3791_RS03245 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGF5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS11145 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKE4 ^@ Function|||Similarity ^@ Belongs to the trehalose phosphatase family.|||Removes the phosphate from trehalose 6-phosphate to produce free trehalose. http://togogenome.org/gene/1775880:D3791_RS02935 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJK5 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1775880:D3791_RS13710 ^@ http://purl.uniprot.org/uniprot/A0A6H0SN95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/1775880:D3791_RS12870 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKS2 ^@ Function|||Similarity ^@ Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.|||Belongs to the IucA/IucC family. http://togogenome.org/gene/1775880:D3791_RS01665 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHC3 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/1775880:D3791_RS07445 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHJ7 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/1775880:D3791_RS02965 ^@ http://purl.uniprot.org/uniprot/A0A6H0SF81 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1775880:D3791_RS13575 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLM8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1775880:D3791_RS02170 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFU6 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1775880:D3791_RS00935 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGZ2 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/1775880:D3791_RS09910 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLV2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS04645 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKH0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS03200 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFP9 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/1775880:D3791_RS09000 ^@ http://purl.uniprot.org/uniprot/A0A6H0SL08 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1775880:D3791_RS00050 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMF6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1775880:D3791_RS05050 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJ24 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS02920 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIK3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/1775880:D3791_RS02230 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHL9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1775880:D3791_RS14435 ^@ http://purl.uniprot.org/uniprot/A0A6H0SM01 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1775880:D3791_RS09430 ^@ http://purl.uniprot.org/uniprot/A0A6H0SI20 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/1775880:D3791_RS14045 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/1775880:D3791_RS04650 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGG9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1775880:D3791_RS13490 ^@ http://purl.uniprot.org/uniprot/A0A6H0SN56 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1775880:D3791_RS16595 ^@ http://purl.uniprot.org/uniprot/A0A6H0SRH4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/1775880:D3791_RS12145 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJB7 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/1775880:D3791_RS16650 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMF6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1775880:D3791_RS02580 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHT0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1775880:D3791_RS01710 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFL9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/1775880:D3791_RS13175 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLG7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/1775880:D3791_RS07710 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIQ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS16540 ^@ http://purl.uniprot.org/uniprot/A0A6H0SN59 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/1775880:D3791_RS13695 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKY3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/1775880:D3791_RS15805 ^@ http://purl.uniprot.org/uniprot/A0A6H0SQ13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/1775880:D3791_RS03005 ^@ http://purl.uniprot.org/uniprot/A0A6H0SI08 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1775880:D3791_RS09540 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJI1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1775880:D3791_RS10255 ^@ http://purl.uniprot.org/uniprot/A0A6H0SM13 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1775880:D3791_RS00430 ^@ http://purl.uniprot.org/uniprot/A0A6H0SDK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.|||Membrane http://togogenome.org/gene/1775880:D3791_RS16555 ^@ http://purl.uniprot.org/uniprot/A0A6H0SQ67 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS00080 ^@ http://purl.uniprot.org/uniprot/A0A6H0SET8 ^@ Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Homodimer. http://togogenome.org/gene/1775880:D3791_RS08995 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJ95 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). http://togogenome.org/gene/1775880:D3791_RS15710 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNE0 ^@ Function ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/1775880:D3791_RS05335 ^@ http://purl.uniprot.org/uniprot/A0A6H0SG25 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1775880:D3791_RS02710 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJG4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1775880:D3791_RS14450 ^@ http://purl.uniprot.org/uniprot/A0A6H0SL54 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1775880:D3791_RS15550 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMJ8 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/1775880:D3791_RS15035 ^@ http://purl.uniprot.org/uniprot/A0A6H0SQP7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1775880:D3791_RS11925 ^@ http://purl.uniprot.org/uniprot/A0A6H0SK93 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/1775880:D3791_RS00915 ^@ http://purl.uniprot.org/uniprot/A0A6H0SII5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/1775880:D3791_RS00945 ^@ http://purl.uniprot.org/uniprot/A0A6H0SE70 ^@ Function|||Similarity ^@ Belongs to the RapZ-like family.|||Displays ATPase and GTPase activities. http://togogenome.org/gene/1775880:D3791_RS03795 ^@ http://purl.uniprot.org/uniprot/A0A6H0SG99 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/1775880:D3791_RS01025 ^@ http://purl.uniprot.org/uniprot/A0A6H0SEL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/1775880:D3791_RS12945 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMY1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/1775880:D3791_RS09085 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMP3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS14545 ^@ http://purl.uniprot.org/uniprot/A0A6H0SM20 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/1775880:D3791_RS16610 ^@ http://purl.uniprot.org/uniprot/A0A6H0SN44 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1775880:D3791_RS07420 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHV4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS03020 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFV6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1775880:D3791_RS03030 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGB6 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1775880:D3791_RS01510 ^@ http://purl.uniprot.org/uniprot/A0A6H0SH92 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/1775880:D3791_RS14200 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNY8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/1775880:D3791_RS04015 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/1775880:D3791_RS08715 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMI3 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/1775880:D3791_RS12845 ^@ http://purl.uniprot.org/uniprot/A0A6H0SN97 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1775880:D3791_RS14440 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNM3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/1775880:D3791_RS16460 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLG1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1775880:D3791_RS08290 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/1775880:D3791_RS13085 ^@ http://purl.uniprot.org/uniprot/A0A6H0SND5 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1775880:D3791_RS06040 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1775880:D3791_RS08295 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHI5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/1775880:D3791_RS03580 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGM0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1775880:D3791_RS00910 ^@ http://purl.uniprot.org/uniprot/A0A6H0SF86 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Membrane http://togogenome.org/gene/1775880:D3791_RS03110 ^@ http://purl.uniprot.org/uniprot/A0A6H0SI33 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1775880:D3791_RS15235 ^@ http://purl.uniprot.org/uniprot/A0A6H0SP11 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1775880:D3791_RS04175 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIL2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1775880:D3791_RS15000 ^@ http://purl.uniprot.org/uniprot/A0A6H0SM97 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS03195 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJP8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the acetyltransferase family. MshD subfamily.|||Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1775880:D3791_RS01415 ^@ http://purl.uniprot.org/uniprot/A0A6H0SEF8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/1775880:D3791_RS08140 ^@ http://purl.uniprot.org/uniprot/A0A6H0SHX3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/1775880:D3791_RS03130 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIP4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/1775880:D3791_RS01185 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIP3 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Feedback inhibited by histidine. http://togogenome.org/gene/1775880:D3791_RS14540 ^@ http://purl.uniprot.org/uniprot/A0A6H0SP51 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/1775880:D3791_RS16345 ^@ http://purl.uniprot.org/uniprot/A0A6H0SMY9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/1775880:D3791_RS16220 ^@ http://purl.uniprot.org/uniprot/A0A6H0SM77 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1775880:D3791_RS03105 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGA5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/1775880:D3791_RS12485 ^@ http://purl.uniprot.org/uniprot/A0A6H0SK49 ^@ Similarity ^@ Belongs to the adenylyl cyclase class-3 family. http://togogenome.org/gene/1775880:D3791_RS00120 ^@ http://purl.uniprot.org/uniprot/A0A6H0SED8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/1775880:D3791_RS14050 ^@ http://purl.uniprot.org/uniprot/A0A6H0SK97 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/1775880:D3791_RS03840 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFN4 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/1775880:D3791_RS04630 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGP7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/1775880:D3791_RS16340 ^@ http://purl.uniprot.org/uniprot/A0A6H0SQ30 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with subunits I, II and III to form cytochrome c oxidase.|||Belongs to the cytochrome c oxidase bacterial subunit CtaF family.|||Cell membrane|||Membrane|||Part of cytochrome c oxidase, its function is unknown. http://togogenome.org/gene/1775880:D3791_RS02030 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJ39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NlpA lipoprotein family.|||Membrane http://togogenome.org/gene/1775880:D3791_RS15605 ^@ http://purl.uniprot.org/uniprot/A0A6H0SP76 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ A probable RNA-binding protein.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm http://togogenome.org/gene/1775880:D3791_RS15845 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLX4 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1775880:D3791_RS08265 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJ10 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1775880:D3791_RS09695 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLB6 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1775880:D3791_RS11335 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJQ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS13150 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJT8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1775880:D3791_RS15855 ^@ http://purl.uniprot.org/uniprot/A0A6H0SN52 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/1775880:D3791_RS00295 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGZ0 ^@ Activity Regulation|||Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.|||Belongs to the TPP enzyme family.|||Binds 1 FAD per subunit.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Cell membrane|||Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus. http://togogenome.org/gene/1775880:D3791_RS11215 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNQ6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cell surface|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.|||capsule|||cell wall http://togogenome.org/gene/1775880:D3791_RS12660 ^@ http://purl.uniprot.org/uniprot/A0A6H0SPG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1775880:D3791_RS13170 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNP7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/1775880:D3791_RS00580 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1775880:D3791_RS08125 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIT6 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/1775880:D3791_RS11510 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKH8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the tryptophan 2,3-dioxygenase family.|||Binds 1 heme group per subunit.|||Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.|||Homotetramer. http://togogenome.org/gene/1775880:D3791_RS00755 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIF3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS13035 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1775880:D3791_RS00850 ^@ http://purl.uniprot.org/uniprot/A0A6H0SER1 ^@ Similarity|||Subunit ^@ Belongs to the transketolase family.|||Homodimer. http://togogenome.org/gene/1775880:D3791_RS03255 ^@ http://purl.uniprot.org/uniprot/A0A6H0SFQ9 ^@ Similarity ^@ Belongs to the UPF0336 family. http://togogenome.org/gene/1775880:D3791_RS14555 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKI0 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/1775880:D3791_RS13475 ^@ http://purl.uniprot.org/uniprot/A0A6H0SKU5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/1775880:D3791_RS04030 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJ46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS00125 ^@ http://purl.uniprot.org/uniprot/A0A6H0SH49 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/1775880:D3791_RS14275 ^@ http://purl.uniprot.org/uniprot/A0A6H0SNJ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1775880:D3791_RS07920 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIB0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1775880:D3791_RS03025 ^@ http://purl.uniprot.org/uniprot/A0A6H0SIM2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1775880:D3791_RS00250 ^@ http://purl.uniprot.org/uniprot/A0A6H0SEW4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1775880:D3791_RS14040 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLT4 ^@ Similarity ^@ Belongs to the prephenate/arogenate dehydrogenase family. http://togogenome.org/gene/1775880:D3791_RS03940 ^@ http://purl.uniprot.org/uniprot/A0A6H0SG34 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1775880:D3791_RS05815 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJG2 ^@ Function|||Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||May catalyze the transamination reaction in phenylalanine biosynthesis. http://togogenome.org/gene/1775880:D3791_RS09375 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJ15 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.|||Homodimer. http://togogenome.org/gene/1775880:D3791_RS02830 ^@ http://purl.uniprot.org/uniprot/A0A6H0SJI5 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1775880:D3791_RS13755 ^@ http://purl.uniprot.org/uniprot/A0A6H0SLN4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1775880:D3791_RS13665 ^@ http://purl.uniprot.org/uniprot/A0A6H0SK26 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1775880:D3791_RS04600 ^@ http://purl.uniprot.org/uniprot/A0A6H0SGF9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/1775880:D3791_RS13975 ^@ http://purl.uniprot.org/uniprot/A0A6H0SQ50 ^@ Function|||Similarity ^@ Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.|||Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. http://togogenome.org/gene/1775880:D3791_RS16590 ^@ http://purl.uniprot.org/uniprot/A0A6H0SN70 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.