http://togogenome.org/gene/1604335:DXZ79_RS03300 ^@ http://purl.uniprot.org/uniprot/A0A386HBD2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS14595 ^@ http://purl.uniprot.org/uniprot/A0A386HG49 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/1604335:DXZ79_RS20075 ^@ http://purl.uniprot.org/uniprot/A0A386HJG3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/1604335:DXZ79_RS09495 ^@ http://purl.uniprot.org/uniprot/A0A386HDL3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS06795 ^@ http://purl.uniprot.org/uniprot/A0A386HCU5 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/1604335:DXZ79_RS07840 ^@ http://purl.uniprot.org/uniprot/A0A386HDG0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial microcompartment|||Belongs to the PduL family.|||Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. http://togogenome.org/gene/1604335:DXZ79_RS01190 ^@ http://purl.uniprot.org/uniprot/A0A386HA69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM86 family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS06740 ^@ http://purl.uniprot.org/uniprot/A0A386HCZ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Cell inner membrane|||Membrane|||Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth. http://togogenome.org/gene/1604335:DXZ79_RS05765 ^@ http://purl.uniprot.org/uniprot/A0A386HC20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0370 family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS15760 ^@ http://purl.uniprot.org/uniprot/A0A386HHG1 ^@ Function|||Similarity ^@ Belongs to the peptidase M16 family.|||Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin. http://togogenome.org/gene/1604335:DXZ79_RS12670 ^@ http://purl.uniprot.org/uniprot/A0A386HFT6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS16420 ^@ http://purl.uniprot.org/uniprot/A0A386HH11 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS15545 ^@ http://purl.uniprot.org/uniprot/A0A386HHI1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS19010 ^@ http://purl.uniprot.org/uniprot/A0A386HIQ2 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1604335:DXZ79_RS17970 ^@ http://purl.uniprot.org/uniprot/A0A386HHQ2 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/1604335:DXZ79_RS03915 ^@ http://purl.uniprot.org/uniprot/A0A386HB85 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS16130 ^@ http://purl.uniprot.org/uniprot/A0A386HHJ6 ^@ Similarity ^@ Belongs to the SdhE FAD assembly factor family. http://togogenome.org/gene/1604335:DXZ79_RS10430 ^@ http://purl.uniprot.org/uniprot/A0A386HEQ5 ^@ Similarity ^@ Belongs to the UPF0482 family. http://togogenome.org/gene/1604335:DXZ79_RS07025 ^@ http://purl.uniprot.org/uniprot/A0A386HCE0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS18525 ^@ http://purl.uniprot.org/uniprot/A0A386HJ02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS19500 ^@ http://purl.uniprot.org/uniprot/A0A386HJC1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/1604335:DXZ79_RS09035 ^@ http://purl.uniprot.org/uniprot/A0A8D4SS21 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS01600 ^@ http://purl.uniprot.org/uniprot/A0A386H9S4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YscJ lipoprotein family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS07905 ^@ http://purl.uniprot.org/uniprot/A0A386HDN6 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/1604335:DXZ79_RS08550 ^@ http://purl.uniprot.org/uniprot/A0A386HD98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS03735 ^@ http://purl.uniprot.org/uniprot/A0A386HBB2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/1604335:DXZ79_RS07960 ^@ http://purl.uniprot.org/uniprot/A0A386HD02 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1604335:DXZ79_RS05400 ^@ http://purl.uniprot.org/uniprot/A0A386HC50 ^@ Function|||Similarity ^@ Belongs to the IscX family.|||May function as iron donor in the assembly of iron-sulfur clusters. http://togogenome.org/gene/1604335:DXZ79_RS18910 ^@ http://purl.uniprot.org/uniprot/A0A386HIN3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1604335:DXZ79_RS01180 ^@ http://purl.uniprot.org/uniprot/A0A386HA76 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sulfur carrier protein TusA family.|||Cytoplasm|||Interacts with IscS.|||Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin. http://togogenome.org/gene/1604335:DXZ79_RS18715 ^@ http://purl.uniprot.org/uniprot/A0A386HIT2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/1604335:DXZ79_RS00950 ^@ http://purl.uniprot.org/uniprot/A0A386HA93 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/1604335:DXZ79_RS12590 ^@ http://purl.uniprot.org/uniprot/A0A386HF72 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS09550 ^@ http://purl.uniprot.org/uniprot/A0A386HDM5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.|||Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)-lipid A.|||Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS09770 ^@ http://purl.uniprot.org/uniprot/A0A386HDR4 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/1604335:DXZ79_RS10955 ^@ http://purl.uniprot.org/uniprot/A0A386HEE8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS11725 ^@ http://purl.uniprot.org/uniprot/A0A386HFB2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/1604335:DXZ79_RS19300 ^@ http://purl.uniprot.org/uniprot/A0A386HJ41 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS18135 ^@ http://purl.uniprot.org/uniprot/A0A386HHS7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1604335:DXZ79_RS18365 ^@ http://purl.uniprot.org/uniprot/A0A8D4ST91 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS19225 ^@ http://purl.uniprot.org/uniprot/A0A386HIX1 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1604335:DXZ79_RS17350 ^@ http://purl.uniprot.org/uniprot/A0A386HHG2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiK family.|||Cytoplasm|||Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both. http://togogenome.org/gene/1604335:DXZ79_RS17015 ^@ http://purl.uniprot.org/uniprot/A0A386HHA5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliN/MopA/SpaO family.|||Cell membrane|||FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS11485 ^@ http://purl.uniprot.org/uniprot/A0A386HFT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS02360 ^@ http://purl.uniprot.org/uniprot/A0A386HA39 ^@ Cofactor|||Function ^@ Binds 1 [2Fe-2S] cluster per subunit.|||Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity. http://togogenome.org/gene/1604335:DXZ79_RS10620 ^@ http://purl.uniprot.org/uniprot/A0A386HE40 ^@ Similarity ^@ Belongs to the alkaline phosphatase family. http://togogenome.org/gene/1604335:DXZ79_RS08825 ^@ http://purl.uniprot.org/uniprot/A0A386HDF5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Catalyzes the sodium-dependent uptake of extracellular L-proline.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS19425 ^@ http://purl.uniprot.org/uniprot/A0A386HJ62 ^@ Function|||Similarity ^@ Belongs to the FeoC family.|||May function as a transcriptional regulator that controls feoABC expression. http://togogenome.org/gene/1604335:DXZ79_RS20210 ^@ http://purl.uniprot.org/uniprot/A0A386HJN4 ^@ Subcellular Location Annotation|||Subunit ^@ Cell inner membrane|||Homodimer.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS15800 ^@ http://purl.uniprot.org/uniprot/A0A8D4N1F6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS17910 ^@ http://purl.uniprot.org/uniprot/A0A386HHP5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS18975 ^@ http://purl.uniprot.org/uniprot/A0A386HI62 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1604335:DXZ79_RS19025 ^@ http://purl.uniprot.org/uniprot/A0A386HI73 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1604335:DXZ79_RS07660 ^@ http://purl.uniprot.org/uniprot/A0A386HCP8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/1604335:DXZ79_RS07335 ^@ http://purl.uniprot.org/uniprot/A0A386HD76 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1604335:DXZ79_RS03320 ^@ http://purl.uniprot.org/uniprot/A0A386HAJ6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein S18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS07795 ^@ http://purl.uniprot.org/uniprot/A0A386HDM0 ^@ Similarity ^@ Belongs to the EutP/PduV family. http://togogenome.org/gene/1604335:DXZ79_RS09310 ^@ http://purl.uniprot.org/uniprot/A0A386HEG9 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/1604335:DXZ79_RS02500 ^@ http://purl.uniprot.org/uniprot/A0A386HAQ6 ^@ Function|||Similarity ^@ Belongs to the MurCDEF family. Mpl subfamily.|||Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate. http://togogenome.org/gene/1604335:DXZ79_RS19555 ^@ http://purl.uniprot.org/uniprot/A0A386HJH5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS15155 ^@ http://purl.uniprot.org/uniprot/A0A386HGF0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.|||Cell membrane|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine. http://togogenome.org/gene/1604335:DXZ79_RS18835 ^@ http://purl.uniprot.org/uniprot/A0A386HIQ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). http://togogenome.org/gene/1604335:DXZ79_RS04345 ^@ http://purl.uniprot.org/uniprot/A0A386HBS8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoS subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. http://togogenome.org/gene/1604335:DXZ79_RS02300 ^@ http://purl.uniprot.org/uniprot/A0A8D4N1G4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueG family.|||Binds 2 [4Fe-4S] clusters per monomer.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS19050 ^@ http://purl.uniprot.org/uniprot/A0A386HIR5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1604335:DXZ79_RS02270 ^@ http://purl.uniprot.org/uniprot/A0A386HAY4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/1604335:DXZ79_RS19260 ^@ http://purl.uniprot.org/uniprot/A0A386HIB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS00365 ^@ http://purl.uniprot.org/uniprot/A0A386H9I9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1604335:DXZ79_RS04625 ^@ http://purl.uniprot.org/uniprot/A0A386HBX7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/1604335:DXZ79_RS16260 ^@ http://purl.uniprot.org/uniprot/A0A386HHP2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family.|||Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS16305 ^@ http://purl.uniprot.org/uniprot/A0A386HGZ1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SprT family.|||Binds 1 zinc ion.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS01460 ^@ http://purl.uniprot.org/uniprot/A0A386H9N4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HemG family.|||Belongs to the flavodoxin family.|||Binds 1 FMN non-covalently per subunit.|||Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS12450 ^@ http://purl.uniprot.org/uniprot/A0A386HF36 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/1604335:DXZ79_RS16410 ^@ http://purl.uniprot.org/uniprot/A0A386HHI2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Fe(2+)-trafficking protein family.|||Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS19415 ^@ http://purl.uniprot.org/uniprot/A0A386HJS5 ^@ Similarity ^@ Belongs to the FeoA family. http://togogenome.org/gene/1604335:DXZ79_RS04880 ^@ http://purl.uniprot.org/uniprot/A0A386HBC6 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/1604335:DXZ79_RS13535 ^@ http://purl.uniprot.org/uniprot/A0A386HGI4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4 family.|||Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS03870 ^@ http://purl.uniprot.org/uniprot/A0A386HAW0 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.|||Repressed under conditions of excess protein secretion capacity and derepressed when protein secretion becomes limiting. This is regulated by SecM. http://togogenome.org/gene/1604335:DXZ79_RS16810 ^@ http://purl.uniprot.org/uniprot/A0A386HH70 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/1604335:DXZ79_RS07800 ^@ http://purl.uniprot.org/uniprot/A0A386HCX2 ^@ Subcellular Location Annotation ^@ Bacterial microcompartment http://togogenome.org/gene/1604335:DXZ79_RS05270 ^@ http://purl.uniprot.org/uniprot/A0A8E4BMJ5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS15565 ^@ http://purl.uniprot.org/uniprot/A0A386HHV8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxA subfamily.|||Cytoplasm|||Homotrimer.|||Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/1604335:DXZ79_RS00875 ^@ http://purl.uniprot.org/uniprot/A0A386H9E4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fimbrial export usher family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS12720 ^@ http://purl.uniprot.org/uniprot/A0A386HFU3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS05855 ^@ http://purl.uniprot.org/uniprot/A0A386HCJ9 ^@ Similarity ^@ Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/1604335:DXZ79_RS20430 ^@ http://purl.uniprot.org/uniprot/A0A386HJX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS07750 ^@ http://purl.uniprot.org/uniprot/A0A386HDL9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/1604335:DXZ79_RS01720 ^@ http://purl.uniprot.org/uniprot/A0A8D4N1T8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/1604335:DXZ79_RS15470 ^@ http://purl.uniprot.org/uniprot/A0A386HH71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS10300 ^@ http://purl.uniprot.org/uniprot/A0A386HER6 ^@ Similarity ^@ Belongs to the ribulokinase family. http://togogenome.org/gene/1604335:DXZ79_RS17170 ^@ http://purl.uniprot.org/uniprot/A0A8E4DFH6 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/1604335:DXZ79_RS17925 ^@ http://purl.uniprot.org/uniprot/A0A386HII7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptC family.|||Cell inner membrane|||Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.|||Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.|||Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. http://togogenome.org/gene/1604335:DXZ79_RS08595 ^@ http://purl.uniprot.org/uniprot/A0A386HDY5 ^@ Function|||Similarity ^@ Belongs to the FlgN family.|||Required for the efficient initiation of filament assembly. http://togogenome.org/gene/1604335:DXZ79_RS04195 ^@ http://purl.uniprot.org/uniprot/A0A386HBD0 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1604335:DXZ79_RS00440 ^@ http://purl.uniprot.org/uniprot/A0A386HA17 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. http://togogenome.org/gene/1604335:DXZ79_RS05065 ^@ http://purl.uniprot.org/uniprot/A0A386HBP4 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/1604335:DXZ79_RS06605 ^@ http://purl.uniprot.org/uniprot/A0A386HCZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS03935 ^@ http://purl.uniprot.org/uniprot/A0A8D4SM40 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS05705 ^@ http://purl.uniprot.org/uniprot/A0A386HC77 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/1604335:DXZ79_RS17280 ^@ http://purl.uniprot.org/uniprot/A0A386HHX7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.|||Cell membrane|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/1604335:DXZ79_RS19295 ^@ http://purl.uniprot.org/uniprot/A0A386HIU8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS09855 ^@ http://purl.uniprot.org/uniprot/A0A386HEI5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone-like protein H-NS family.|||nucleoid http://togogenome.org/gene/1604335:DXZ79_RS13245 ^@ http://purl.uniprot.org/uniprot/A0A8D4N455 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YejK family.|||nucleoid http://togogenome.org/gene/1604335:DXZ79_RS06200 ^@ http://purl.uniprot.org/uniprot/A0A386HCH3 ^@ Similarity ^@ Belongs to the Rht family. http://togogenome.org/gene/1604335:DXZ79_RS04995 ^@ http://purl.uniprot.org/uniprot/A0A386HC43 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.|||Binds 2 nickel ions per subunit.|||Carbamylation allows a single lysine to coordinate two nickel ions.|||Carboxylation allows a single lysine to coordinate two nickel ions.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1604335:DXZ79_RS12585 ^@ http://purl.uniprot.org/uniprot/A0A386HG05 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZapC family.|||Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.|||Cytoplasm|||Interacts directly with FtsZ. http://togogenome.org/gene/1604335:DXZ79_RS16950 ^@ http://purl.uniprot.org/uniprot/A0A8D4SPA4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1604335:DXZ79_RS18670 ^@ http://purl.uniprot.org/uniprot/A0A386HIX4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Rsd/AlgQ family.|||Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.|||Cytoplasm|||Interacts with RpoD. http://togogenome.org/gene/1604335:DXZ79_RS09455 ^@ http://purl.uniprot.org/uniprot/A0A386HE64 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS15830 ^@ http://purl.uniprot.org/uniprot/A0A386HI07 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.|||Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS11735 ^@ http://purl.uniprot.org/uniprot/A0A386HER7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S33 family.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS03430 ^@ http://purl.uniprot.org/uniprot/A0A386HAL6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TrpR family.|||Cytoplasm|||Homodimer.|||This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. http://togogenome.org/gene/1604335:DXZ79_RS09475 ^@ http://purl.uniprot.org/uniprot/A0A8D4MZD7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.|||Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS11560 ^@ http://purl.uniprot.org/uniprot/A0A386HEJ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ProQ family.|||Cytoplasm|||RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. http://togogenome.org/gene/1604335:DXZ79_RS01610 ^@ http://purl.uniprot.org/uniprot/A0A386HAB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SctL stator family.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS09850 ^@ http://purl.uniprot.org/uniprot/A0A386HEE1 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1604335:DXZ79_RS05075 ^@ http://purl.uniprot.org/uniprot/A0A386HC72 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/1604335:DXZ79_RS10740 ^@ http://purl.uniprot.org/uniprot/A0A386HF06 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.|||Belongs to the azoreductase type 1 family.|||Binds 1 FMN per subunit.|||Homodimer.|||Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones. http://togogenome.org/gene/1604335:DXZ79_RS05275 ^@ http://purl.uniprot.org/uniprot/A0A386HBN1 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase Slt family.|||Cell outer membrane|||In the C-terminal section; belongs to the transglycosylase Slt family.|||In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.|||The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain. http://togogenome.org/gene/1604335:DXZ79_RS04835 ^@ http://purl.uniprot.org/uniprot/A0A386HBV6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.|||Binds 2 Zn(2+) ions per subunit.|||Monomer.|||Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. http://togogenome.org/gene/1604335:DXZ79_RS16275 ^@ http://purl.uniprot.org/uniprot/A0A386HHF3 ^@ Function|||Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.|||Catalyzes the biosynthesis of agmatine from arginine. http://togogenome.org/gene/1604335:DXZ79_RS16265 ^@ http://purl.uniprot.org/uniprot/A0A386HHV5 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1604335:DXZ79_RS15475 ^@ http://purl.uniprot.org/uniprot/A0A386HGJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS15460 ^@ http://purl.uniprot.org/uniprot/A0A386HHT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gmhB family.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS09350 ^@ http://purl.uniprot.org/uniprot/A0A386HE99 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/1604335:DXZ79_RS19360 ^@ http://purl.uniprot.org/uniprot/A0A386HJR6 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HSP33 family.|||Cytoplasm|||Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.|||Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive. http://togogenome.org/gene/1604335:DXZ79_RS04810 ^@ http://purl.uniprot.org/uniprot/A0A386HBU1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS00410 ^@ http://purl.uniprot.org/uniprot/A0A386H9S5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS17340 ^@ http://purl.uniprot.org/uniprot/A0A8D4N6W1 ^@ Similarity ^@ Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family. http://togogenome.org/gene/1604335:DXZ79_RS17565 ^@ http://purl.uniprot.org/uniprot/A0A386HHJ2 ^@ Similarity|||Subunit ^@ Belongs to the glutaminase family.|||Homotetramer. http://togogenome.org/gene/1604335:DXZ79_RS08600 ^@ http://purl.uniprot.org/uniprot/A0A386HDA8 ^@ Function|||Similarity ^@ Belongs to the FlgM family.|||Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA. http://togogenome.org/gene/1604335:DXZ79_RS12955 ^@ http://purl.uniprot.org/uniprot/A0A386HFS9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein PotD/PotF family.|||Periplasm|||Required for the activity of the bacterial periplasmic transport system of putrescine. http://togogenome.org/gene/1604335:DXZ79_RS14015 ^@ http://purl.uniprot.org/uniprot/A0A386HFT9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. Thiolase family.|||Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.|||Cytoplasm|||Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI). http://togogenome.org/gene/1604335:DXZ79_RS15235 ^@ http://purl.uniprot.org/uniprot/A0A386HGE6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/1604335:DXZ79_RS00820 ^@ http://purl.uniprot.org/uniprot/A0A386H9G0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS18325 ^@ http://purl.uniprot.org/uniprot/A0A8D4N780 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS04735 ^@ http://purl.uniprot.org/uniprot/A0A8D4MZX4 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS07310 ^@ http://purl.uniprot.org/uniprot/A0A386HDC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS00960 ^@ http://purl.uniprot.org/uniprot/A0A386HA36 ^@ Function|||Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family.|||Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate. http://togogenome.org/gene/1604335:DXZ79_RS12280 ^@ http://purl.uniprot.org/uniprot/A0A386HF12 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS00170 ^@ http://purl.uniprot.org/uniprot/A0A386H9R8 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. http://togogenome.org/gene/1604335:DXZ79_RS05830 ^@ http://purl.uniprot.org/uniprot/A0A386HC74 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NapF family.|||Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.|||Cytoplasm|||Interacts with the cytoplasmic NapA precursor. http://togogenome.org/gene/1604335:DXZ79_RS18205 ^@ http://purl.uniprot.org/uniprot/A0A386HI68 ^@ Function|||Similarity ^@ Belongs to the Dus family. DusB subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/1604335:DXZ79_RS15105 ^@ http://purl.uniprot.org/uniprot/A0A386HGE0 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/1604335:DXZ79_RS15695 ^@ http://purl.uniprot.org/uniprot/A0A386HHF1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS01400 ^@ http://purl.uniprot.org/uniprot/A0A386HA51 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatB family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1604335:DXZ79_RS01225 ^@ http://purl.uniprot.org/uniprot/A0A386HA56 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell inner membrane|||Forms a membrane-associated complex with FtsE.|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/1604335:DXZ79_RS15310 ^@ http://purl.uniprot.org/uniprot/A0A8D4N5R4 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/1604335:DXZ79_RS18945 ^@ http://purl.uniprot.org/uniprot/A0A386HIS1 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1604335:DXZ79_RS13720 ^@ http://purl.uniprot.org/uniprot/A0A386HG45 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS15620 ^@ http://purl.uniprot.org/uniprot/A0A386HH49 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS00895 ^@ http://purl.uniprot.org/uniprot/A0A386H9Z6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. UvrD subfamily.|||Homodimer.|||Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. http://togogenome.org/gene/1604335:DXZ79_RS19760 ^@ http://purl.uniprot.org/uniprot/A0A386HJY3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmJ family.|||Cytoplasm|||Specifically methylates the guanosine in position 1516 of 16S rRNA. http://togogenome.org/gene/1604335:DXZ79_RS18380 ^@ http://purl.uniprot.org/uniprot/A0A8D4N5S9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell inner membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/1604335:DXZ79_RS08635 ^@ http://purl.uniprot.org/uniprot/A0A386HDV0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1604335:DXZ79_RS06110 ^@ http://purl.uniprot.org/uniprot/A0A386HCP2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS02705 ^@ http://purl.uniprot.org/uniprot/A0A386HB20 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-I family. http://togogenome.org/gene/1604335:DXZ79_RS06545 ^@ http://purl.uniprot.org/uniprot/A0A8D4N200 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/1604335:DXZ79_RS12795 ^@ http://purl.uniprot.org/uniprot/A0A386HGI3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS06765 ^@ http://purl.uniprot.org/uniprot/A0A386HD24 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/1604335:DXZ79_RS05970 ^@ http://purl.uniprot.org/uniprot/A0A8D4SR80 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS12495 ^@ http://purl.uniprot.org/uniprot/A0A386HFE5 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS04725 ^@ http://purl.uniprot.org/uniprot/A0A8D4SQ07 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/1604335:DXZ79_RS07030 ^@ http://purl.uniprot.org/uniprot/A0A386HCD3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS03885 ^@ http://purl.uniprot.org/uniprot/A0A386HBJ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZapD family.|||Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.|||Cytoplasm|||Interacts with FtsZ. http://togogenome.org/gene/1604335:DXZ79_RS03185 ^@ http://purl.uniprot.org/uniprot/A0A386HAH1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS03950 ^@ http://purl.uniprot.org/uniprot/A0A386HB40 ^@ Function|||Subunit ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).|||Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/1604335:DXZ79_RS12235 ^@ http://purl.uniprot.org/uniprot/A0A386HFK9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/1604335:DXZ79_RS07170 ^@ http://purl.uniprot.org/uniprot/A0A386HCV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS09450 ^@ http://purl.uniprot.org/uniprot/A0A386HDK5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell inner membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS01670 ^@ http://purl.uniprot.org/uniprot/A0A8D4SP18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0394 family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS08560 ^@ http://purl.uniprot.org/uniprot/A0A386HE22 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/1604335:DXZ79_RS12645 ^@ http://purl.uniprot.org/uniprot/A0A386HGE7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MukE family.|||Interacts, and probably forms a ternary complex, with MukF and MukB. The complex formation is stimulated by calcium or magnesium.|||Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.|||nucleoid http://togogenome.org/gene/1604335:DXZ79_RS17395 ^@ http://purl.uniprot.org/uniprot/A0A386HHZ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.|||Homooctamer. http://togogenome.org/gene/1604335:DXZ79_RS08850 ^@ http://purl.uniprot.org/uniprot/A0A386HDB1 ^@ Cofactor|||Similarity ^@ Belongs to the WrbA family.|||Binds 1 FMN per monomer. http://togogenome.org/gene/1604335:DXZ79_RS17955 ^@ http://purl.uniprot.org/uniprot/A0A386HI99 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RapZ-like family. RapZ subfamily.|||Homotrimer.|||Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS. http://togogenome.org/gene/1604335:DXZ79_RS08605 ^@ http://purl.uniprot.org/uniprot/A0A386HDJ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FlgA family.|||Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS02700 ^@ http://purl.uniprot.org/uniprot/A0A386HA99 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.|||Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS04765 ^@ http://purl.uniprot.org/uniprot/A0A386HBT3 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/1604335:DXZ79_RS07785 ^@ http://purl.uniprot.org/uniprot/A0A386HDF0 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1604335:DXZ79_RS10545 ^@ http://purl.uniprot.org/uniprot/A0A386HEE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS13375 ^@ http://purl.uniprot.org/uniprot/A0A8D4N6D0 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Autophosphorylated. Activation probably requires a transfer of a phosphate group from a His in the transmitter domain to an Asp in the receiver domain.|||Belongs to the RcsC family.|||Cell inner membrane|||Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane-associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.|||Interacts with RcsD. http://togogenome.org/gene/1604335:DXZ79_RS11145 ^@ http://purl.uniprot.org/uniprot/A0A386HF18 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/1604335:DXZ79_RS11855 ^@ http://purl.uniprot.org/uniprot/A0A386HFL6 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/1604335:DXZ79_RS15225 ^@ http://purl.uniprot.org/uniprot/A0A386HGX7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS18920 ^@ http://purl.uniprot.org/uniprot/A0A386HI64 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1604335:DXZ79_RS07050 ^@ http://purl.uniprot.org/uniprot/A0A386HJZ2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/1604335:DXZ79_RS17935 ^@ http://purl.uniprot.org/uniprot/A0A386HI14 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system. http://togogenome.org/gene/1604335:DXZ79_RS11585 ^@ http://purl.uniprot.org/uniprot/A0A386HER2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS19075 ^@ http://purl.uniprot.org/uniprot/A0A386HI96 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DsrH/TusB family.|||Cytoplasm|||Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.|||Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. http://togogenome.org/gene/1604335:DXZ79_RS11055 ^@ http://purl.uniprot.org/uniprot/A0A386HEN1 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family. Monothiol subfamily.|||Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. http://togogenome.org/gene/1604335:DXZ79_RS01380 ^@ http://purl.uniprot.org/uniprot/A0A8D4MX13 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). http://togogenome.org/gene/1604335:DXZ79_RS18570 ^@ http://purl.uniprot.org/uniprot/A0A386HIQ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the AceK family.|||Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS08290 ^@ http://purl.uniprot.org/uniprot/A0A386HD09 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CitD family.|||Covalent carrier of the coenzyme of citrate lyase.|||Cytoplasm|||Oligomer with a subunit composition of (alpha,beta,gamma)6. http://togogenome.org/gene/1604335:DXZ79_RS08260 ^@ http://purl.uniprot.org/uniprot/A0A386HD46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS16680 ^@ http://purl.uniprot.org/uniprot/A0A386HHT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS09940 ^@ http://purl.uniprot.org/uniprot/A0A386HDU2 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1604335:DXZ79_RS12310 ^@ http://purl.uniprot.org/uniprot/A0A386HG78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS15140 ^@ http://purl.uniprot.org/uniprot/A0A386HH01 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS06940 ^@ http://purl.uniprot.org/uniprot/A0A386HCV5 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/1604335:DXZ79_RS06955 ^@ http://purl.uniprot.org/uniprot/A0A386HCR5 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/1604335:DXZ79_RS02695 ^@ http://purl.uniprot.org/uniprot/A0A8E4BMD1 ^@ Similarity ^@ Belongs to the UPF0213 family. http://togogenome.org/gene/1604335:DXZ79_RS12135 ^@ http://purl.uniprot.org/uniprot/A0A386HFL9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LpoB family.|||Interacts with PBP1b.|||Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). http://togogenome.org/gene/1604335:DXZ79_RS11135 ^@ http://purl.uniprot.org/uniprot/A0A386HEC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YkuD family.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS04495 ^@ http://purl.uniprot.org/uniprot/A0A386HBN4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS05475 ^@ http://purl.uniprot.org/uniprot/A0A386HC45 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/1604335:DXZ79_RS03325 ^@ http://purl.uniprot.org/uniprot/A0A8E4BM91 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/1604335:DXZ79_RS00630 ^@ http://purl.uniprot.org/uniprot/A0A8D4MWU3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PEPCase type 1 family.|||Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.|||Homotetramer. http://togogenome.org/gene/1604335:DXZ79_RS15110 ^@ http://purl.uniprot.org/uniprot/A0A386HGU3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS12755 ^@ http://purl.uniprot.org/uniprot/A0A386HFS5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS15625 ^@ http://purl.uniprot.org/uniprot/A0A386HH97 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1604335:DXZ79_RS08640 ^@ http://purl.uniprot.org/uniprot/A0A386HDR6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgH family.|||Cell outer membrane|||Membrane|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/1604335:DXZ79_RS00975 ^@ http://purl.uniprot.org/uniprot/A0A8D4SQE1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WzyE family.|||Cell inner membrane|||Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.|||Probably part of a complex composed of WzxE, WzyE and WzzE. http://togogenome.org/gene/1604335:DXZ79_RS07690 ^@ http://purl.uniprot.org/uniprot/A0A386HDK6 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.|||Feedback inhibited by histidine. http://togogenome.org/gene/1604335:DXZ79_RS08520 ^@ http://purl.uniprot.org/uniprot/A0A8D4N3X5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FlhC family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.|||Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers. http://togogenome.org/gene/1604335:DXZ79_RS04055 ^@ http://purl.uniprot.org/uniprot/A0A386HBG3 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/1604335:DXZ79_RS18335 ^@ http://purl.uniprot.org/uniprot/A0A386HHW8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS09625 ^@ http://purl.uniprot.org/uniprot/A0A386HEE6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily.|||Interacts with MinC and FtsZ.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS12125 ^@ http://purl.uniprot.org/uniprot/A0A386HEY1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.|||Cytoplasm|||Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. http://togogenome.org/gene/1604335:DXZ79_RS19015 ^@ http://purl.uniprot.org/uniprot/A0A386HIZ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1604335:DXZ79_RS18960 ^@ http://purl.uniprot.org/uniprot/A0A386HIP3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1604335:DXZ79_RS17725 ^@ http://purl.uniprot.org/uniprot/A0A386HID1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1604335:DXZ79_RS03555 ^@ http://purl.uniprot.org/uniprot/A0A8D4SQU4 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS09160 ^@ http://purl.uniprot.org/uniprot/A0A8D4SMY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS12595 ^@ http://purl.uniprot.org/uniprot/A0A386HFL2 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/1604335:DXZ79_RS11275 ^@ http://purl.uniprot.org/uniprot/A0A386HEL1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family.|||Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS10365 ^@ http://purl.uniprot.org/uniprot/A0A386HEJ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS13445 ^@ http://purl.uniprot.org/uniprot/A0A386HFZ5 ^@ Function|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.|||Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB). http://togogenome.org/gene/1604335:DXZ79_RS11205 ^@ http://purl.uniprot.org/uniprot/A0A386HEJ3 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/1604335:DXZ79_RS04805 ^@ http://purl.uniprot.org/uniprot/A0A386HBN5 ^@ Subunit ^@ Monomer. http://togogenome.org/gene/1604335:DXZ79_RS01490 ^@ http://purl.uniprot.org/uniprot/A0A386H9Q6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Cell inner membrane|||Membrane|||Transports acetate. http://togogenome.org/gene/1604335:DXZ79_RS10635 ^@ http://purl.uniprot.org/uniprot/A0A386HEV1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA gyrase inhibitor family.|||Cytoplasm|||Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.|||Interacts with DNA gyrase. http://togogenome.org/gene/1604335:DXZ79_RS00205 ^@ http://purl.uniprot.org/uniprot/A0A386H9X9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS05630 ^@ http://purl.uniprot.org/uniprot/A0A386HC91 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS09585 ^@ http://purl.uniprot.org/uniprot/A0A386HDY8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.|||Catalyzes the excretion of spermidine.|||Cell inner membrane|||Cell membrane|||Forms a complex with MdtJ.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS15560 ^@ http://purl.uniprot.org/uniprot/A0A386HH18 ^@ Function|||Similarity ^@ Belongs to the LpxB family.|||Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/1604335:DXZ79_RS10835 ^@ http://purl.uniprot.org/uniprot/A0A386HE76 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1604335:DXZ79_RS06225 ^@ http://purl.uniprot.org/uniprot/A0A386HCW4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS14065 ^@ http://purl.uniprot.org/uniprot/A0A386HFV0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmC/CycZ/HelC family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/1604335:DXZ79_RS13255 ^@ http://purl.uniprot.org/uniprot/A0A386HGR1 ^@ Similarity ^@ To H.influenzae HI_0842. http://togogenome.org/gene/1604335:DXZ79_RS17930 ^@ http://purl.uniprot.org/uniprot/A0A386HIP2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptA family.|||Component of the lipopolysaccharide transport and assembly complex.|||Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS10160 ^@ http://purl.uniprot.org/uniprot/A0A386HE73 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/1604335:DXZ79_RS15580 ^@ http://purl.uniprot.org/uniprot/A0A386HGL0 ^@ Similarity ^@ Belongs to the skp family. http://togogenome.org/gene/1604335:DXZ79_RS09525 ^@ http://purl.uniprot.org/uniprot/A0A386HE55 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpB subfamily.|||Cell inner membrane|||Membrane|||Proton-dependent permease that transports di- and tripeptides. http://togogenome.org/gene/1604335:DXZ79_RS03475 ^@ http://purl.uniprot.org/uniprot/A0A386HB04 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/1604335:DXZ79_RS00490 ^@ http://purl.uniprot.org/uniprot/A0A386H9C7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.|||Cell inner membrane|||Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+). May be involved in zinc and iron detoxification by efflux.|||Homodimer.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS15525 ^@ http://purl.uniprot.org/uniprot/A0A8D4N4U7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/1604335:DXZ79_RS00845 ^@ http://purl.uniprot.org/uniprot/A0A386HA14 ^@ Similarity ^@ Belongs to the colicins ColE2/ColE8/ColE9 and pyocins S1/S2 family. http://togogenome.org/gene/1604335:DXZ79_RS13545 ^@ http://purl.uniprot.org/uniprot/A0A386HG15 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1604335:DXZ79_RS19355 ^@ http://purl.uniprot.org/uniprot/A0A386HIV6 ^@ Similarity ^@ Belongs to the HSP15 family. http://togogenome.org/gene/1604335:DXZ79_RS18795 ^@ http://purl.uniprot.org/uniprot/A0A386HIU3 ^@ Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.|||Belongs to the biotin--protein ligase family. http://togogenome.org/gene/1604335:DXZ79_RS09700 ^@ http://purl.uniprot.org/uniprot/A0A8E3ZIA7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Belongs to the major facilitator superfamily. TCR/Tet family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter. http://togogenome.org/gene/1604335:DXZ79_RS06460 ^@ http://purl.uniprot.org/uniprot/A0A386HD06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS07725 ^@ http://purl.uniprot.org/uniprot/A0A386HD99 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS12915 ^@ http://purl.uniprot.org/uniprot/A0A386HFW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS18515 ^@ http://purl.uniprot.org/uniprot/A0A386HIP8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 1 family.|||Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.|||Periplasm|||The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).|||sn-glycerol-3-phosphate and glycerophosphoryl diester-binding protein interacts with the binding protein-dependent transport system UgpACE. http://togogenome.org/gene/1604335:DXZ79_RS08215 ^@ http://purl.uniprot.org/uniprot/A0A8D4SRX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS07540 ^@ http://purl.uniprot.org/uniprot/A0A386HD61 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/1604335:DXZ79_RS03635 ^@ http://purl.uniprot.org/uniprot/A0A386HJT8 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PdxA family.|||Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).|||Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).|||Cytoplasm|||Homodimer.|||The active site is located at the dimer interface. http://togogenome.org/gene/1604335:DXZ79_RS16710 ^@ http://purl.uniprot.org/uniprot/A0A386HI27 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS16100 ^@ http://purl.uniprot.org/uniprot/A0A386HHL2 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.|||FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges the bottom DNA strands. http://togogenome.org/gene/1604335:DXZ79_RS16350 ^@ http://purl.uniprot.org/uniprot/A0A8D4N457 ^@ Function|||Similarity|||Subunit ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Monomer.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/1604335:DXZ79_RS14850 ^@ http://purl.uniprot.org/uniprot/A0A386HG83 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS10285 ^@ http://purl.uniprot.org/uniprot/A0A386HE46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS02495 ^@ http://purl.uniprot.org/uniprot/A0A386HAC6 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FBPase class 1 family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS19520 ^@ http://purl.uniprot.org/uniprot/A0A386HJU5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS03510 ^@ http://purl.uniprot.org/uniprot/A0A386HBD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS16230 ^@ http://purl.uniprot.org/uniprot/A0A386HI82 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LysE/ArgO transporter (TC 2.A.75) family.|||Cell membrane|||Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS09840 ^@ http://purl.uniprot.org/uniprot/A0A386HDS4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS07190 ^@ http://purl.uniprot.org/uniprot/A0A386HCZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS09355 ^@ http://purl.uniprot.org/uniprot/A0A386HDN8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/1604335:DXZ79_RS14585 ^@ http://purl.uniprot.org/uniprot/A0A386HGW0 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/1604335:DXZ79_RS11675 ^@ http://purl.uniprot.org/uniprot/A0A386HEQ7 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1604335:DXZ79_RS14640 ^@ http://purl.uniprot.org/uniprot/A0A386HH24 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS17320 ^@ http://purl.uniprot.org/uniprot/A0A386HHY3 ^@ Function|||Similarity|||Subunit ^@ Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.|||Belongs to the Nudix hydrolase family. NudF subfamily.|||Belongs to the Nudix hydrolase family. NudK subfamily.|||Homodimer.|||Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate. http://togogenome.org/gene/1604335:DXZ79_RS19085 ^@ http://purl.uniprot.org/uniprot/A0A386HIY6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DsrE/TusD family.|||Cytoplasm|||Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.|||Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. http://togogenome.org/gene/1604335:DXZ79_RS18165 ^@ http://purl.uniprot.org/uniprot/A0A386HJ69 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the MsrP family.|||Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.|||Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).|||Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide. http://togogenome.org/gene/1604335:DXZ79_RS05175 ^@ http://purl.uniprot.org/uniprot/A0A386HBH5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.|||Belongs to the RseA family.|||Cell inner membrane|||Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB. http://togogenome.org/gene/1604335:DXZ79_RS10380 ^@ http://purl.uniprot.org/uniprot/A0A386HEP5 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/1604335:DXZ79_RS19950 ^@ http://purl.uniprot.org/uniprot/A0A386HJ55 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/1604335:DXZ79_RS02675 ^@ http://purl.uniprot.org/uniprot/A0A386HB46 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase U32 family. UbiV subfamily.|||Forms an heterodimer with UbiU.|||Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway. http://togogenome.org/gene/1604335:DXZ79_RS10770 ^@ http://purl.uniprot.org/uniprot/A0A386HEW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS02160 ^@ http://purl.uniprot.org/uniprot/A0A386HAK7 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/1604335:DXZ79_RS06380 ^@ http://purl.uniprot.org/uniprot/A0A386HCF5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS10975 ^@ http://purl.uniprot.org/uniprot/A0A386HEF4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS08500 ^@ http://purl.uniprot.org/uniprot/A0A386HD89 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.|||Cell inner membrane|||Mediates magnesium influx to the cytosol. http://togogenome.org/gene/1604335:DXZ79_RS06395 ^@ http://purl.uniprot.org/uniprot/A0A386HC28 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/1604335:DXZ79_RS02465 ^@ http://purl.uniprot.org/uniprot/A0A8E4MBN3 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/1604335:DXZ79_RS05015 ^@ http://purl.uniprot.org/uniprot/A0A386HBX2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreD family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/1604335:DXZ79_RS12820 ^@ http://purl.uniprot.org/uniprot/A0A386HFW3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/1604335:DXZ79_RS19080 ^@ http://purl.uniprot.org/uniprot/A0A386HI81 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DsrF/TusC family.|||Cytoplasm|||Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.|||Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. http://togogenome.org/gene/1604335:DXZ79_RS05280 ^@ http://purl.uniprot.org/uniprot/A0A386HBJ4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||In the N-terminal section; belongs to the FGAMS family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. http://togogenome.org/gene/1604335:DXZ79_RS02180 ^@ http://purl.uniprot.org/uniprot/A0A386H9Y9 ^@ Similarity ^@ Belongs to the class-II fumarase/aspartase family. Aspartase subfamily. http://togogenome.org/gene/1604335:DXZ79_RS03140 ^@ http://purl.uniprot.org/uniprot/A0A386HB08 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DeoC/FbaB aldolase family.|||Cytoplasm|||Homodecamer.|||Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA. http://togogenome.org/gene/1604335:DXZ79_RS01410 ^@ http://purl.uniprot.org/uniprot/A0A8D4MYW5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair.|||Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS07385 ^@ http://purl.uniprot.org/uniprot/A0A386HCK3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS11235 ^@ http://purl.uniprot.org/uniprot/A0A386HFH4 ^@ Function|||Similarity ^@ Belongs to the SELO family.|||Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). http://togogenome.org/gene/1604335:DXZ79_RS15960 ^@ http://purl.uniprot.org/uniprot/A0A386HGS9 ^@ Similarity ^@ Belongs to the beta-class carbonic anhydrase family. http://togogenome.org/gene/1604335:DXZ79_RS09870 ^@ http://purl.uniprot.org/uniprot/A0A386HEB2 ^@ Similarity ^@ In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.|||In the N-terminal section; belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1604335:DXZ79_RS01170 ^@ http://purl.uniprot.org/uniprot/A0A386HAD1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DcrB family.|||Cell membrane|||Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. Essential for lipoprotein maturation under conditions where membrane fluidity may be altered. http://togogenome.org/gene/1604335:DXZ79_RS16215 ^@ http://purl.uniprot.org/uniprot/A0A386HHU2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS11165 ^@ http://purl.uniprot.org/uniprot/A0A386HEX7 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/1604335:DXZ79_RS07270 ^@ http://purl.uniprot.org/uniprot/A0A8D4SRF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS07425 ^@ http://purl.uniprot.org/uniprot/A0A386HCX5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS11450 ^@ http://purl.uniprot.org/uniprot/A0A386HEM5 ^@ Similarity ^@ Belongs to the fructosamine kinase family. http://togogenome.org/gene/1604335:DXZ79_RS16315 ^@ http://purl.uniprot.org/uniprot/A0A386HHQ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/1604335:DXZ79_RS14905 ^@ http://purl.uniprot.org/uniprot/A0A386HG93 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS05070 ^@ http://purl.uniprot.org/uniprot/A0A386HBX9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1604335:DXZ79_RS17710 ^@ http://purl.uniprot.org/uniprot/A0A386HI52 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS08735 ^@ http://purl.uniprot.org/uniprot/A0A8D4SS05 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/1604335:DXZ79_RS06455 ^@ http://purl.uniprot.org/uniprot/A0A386HCN3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS08040 ^@ http://purl.uniprot.org/uniprot/A0A386HDT3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 2 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1604335:DXZ79_RS09945 ^@ http://purl.uniprot.org/uniprot/A0A386HDU1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TonB family.|||Cell inner membrane|||Homodimer. Forms a complex with the accessory proteins ExbB and ExbD.|||Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. http://togogenome.org/gene/1604335:DXZ79_RS02535 ^@ http://purl.uniprot.org/uniprot/A0A386HAR2 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1604335:DXZ79_RS18985 ^@ http://purl.uniprot.org/uniprot/A0A386HJ30 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1604335:DXZ79_RS16790 ^@ http://purl.uniprot.org/uniprot/A0A8D4N1Q8 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/1604335:DXZ79_RS14835 ^@ http://purl.uniprot.org/uniprot/A0A386HGQ3 ^@ Similarity ^@ Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family. http://togogenome.org/gene/1604335:DXZ79_RS11925 ^@ http://purl.uniprot.org/uniprot/A0A386HFA3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS15510 ^@ http://purl.uniprot.org/uniprot/A0A386HHV0 ^@ Similarity ^@ Belongs to the UPF0253 family. http://togogenome.org/gene/1604335:DXZ79_RS04225 ^@ http://purl.uniprot.org/uniprot/A0A386HBS1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family.|||Binds 1 copper ion per subunit.|||Binds 1 zinc ion per subunit.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/1604335:DXZ79_RS18585 ^@ http://purl.uniprot.org/uniprot/A0A386HIL8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. http://togogenome.org/gene/1604335:DXZ79_RS14020 ^@ http://purl.uniprot.org/uniprot/A0A386HGF7 ^@ Similarity ^@ Belongs to the UPF0381 family. http://togogenome.org/gene/1604335:DXZ79_RS07575 ^@ http://purl.uniprot.org/uniprot/A0A8D4MYU5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS14725 ^@ http://purl.uniprot.org/uniprot/A0A386HGN5 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/1604335:DXZ79_RS00905 ^@ http://purl.uniprot.org/uniprot/A0A386H9L3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DEAD box helicase family. RhlB subfamily.|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA. http://togogenome.org/gene/1604335:DXZ79_RS07145 ^@ http://purl.uniprot.org/uniprot/A0A8D4MYP8 ^@ Similarity ^@ Belongs to the peptidase S11 family. http://togogenome.org/gene/1604335:DXZ79_RS09555 ^@ http://purl.uniprot.org/uniprot/A0A386HE87 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1604335:DXZ79_RS19175 ^@ http://purl.uniprot.org/uniprot/A0A386HIW2 ^@ Similarity ^@ Belongs to the UPF0270 family. http://togogenome.org/gene/1604335:DXZ79_RS03180 ^@ http://purl.uniprot.org/uniprot/A0A386HAZ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS10170 ^@ http://purl.uniprot.org/uniprot/A0A386HDX6 ^@ Similarity ^@ Belongs to the aldolase class II family. AraD/FucA subfamily. http://togogenome.org/gene/1604335:DXZ79_RS16255 ^@ http://purl.uniprot.org/uniprot/A0A386HHL0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.|||Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS07610 ^@ http://purl.uniprot.org/uniprot/A0A386HD73 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS09070 ^@ http://purl.uniprot.org/uniprot/A0A386HDD9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS05390 ^@ http://purl.uniprot.org/uniprot/A0A386HBL6 ^@ Function|||Similarity ^@ Belongs to the heat shock protein 70 family.|||Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. http://togogenome.org/gene/1604335:DXZ79_RS04230 ^@ http://purl.uniprot.org/uniprot/A0A386HBJ7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS04125 ^@ http://purl.uniprot.org/uniprot/A0A8D4MZQ7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS05395 ^@ http://purl.uniprot.org/uniprot/A0A386HCB7 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/1604335:DXZ79_RS11650 ^@ http://purl.uniprot.org/uniprot/A0A386HF58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS16925 ^@ http://purl.uniprot.org/uniprot/A0A8D4N322 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgH family.|||Cell outer membrane|||Membrane|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/1604335:DXZ79_RS12295 ^@ http://purl.uniprot.org/uniprot/A0A386HFV7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the MSOX/MTOX family. MTOX subfamily.|||Binds 1 FAD per subunit.|||Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS05440 ^@ http://purl.uniprot.org/uniprot/A0A386HC54 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. http://togogenome.org/gene/1604335:DXZ79_RS05365 ^@ http://purl.uniprot.org/uniprot/A0A8D4SR44 ^@ Cofactor|||Function ^@ Binds 1 [2Fe-2S] cluster.|||Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. http://togogenome.org/gene/1604335:DXZ79_RS19040 ^@ http://purl.uniprot.org/uniprot/A0A386HJ84 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/1604335:DXZ79_RS07845 ^@ http://purl.uniprot.org/uniprot/A0A386HDC2 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial microcompartment|||Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/1604335:DXZ79_RS00415 ^@ http://purl.uniprot.org/uniprot/A0A8E4DF90 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the zinc-containing alcohol dehydrogenase family.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1604335:DXZ79_RS17405 ^@ http://purl.uniprot.org/uniprot/A0A386HHG3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/1604335:DXZ79_RS01230 ^@ http://purl.uniprot.org/uniprot/A0A386HA85 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoH subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. http://togogenome.org/gene/1604335:DXZ79_RS02540 ^@ http://purl.uniprot.org/uniprot/A0A386HAW8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/1604335:DXZ79_RS06505 ^@ http://purl.uniprot.org/uniprot/A0A386HCP4 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/1604335:DXZ79_RS07515 ^@ http://purl.uniprot.org/uniprot/A0A386HDG9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS14070 ^@ http://purl.uniprot.org/uniprot/A0A386HGG6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmB/CycW/HelB family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/1604335:DXZ79_RS12675 ^@ http://purl.uniprot.org/uniprot/A0A386HFX6 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/1604335:DXZ79_RS16295 ^@ http://purl.uniprot.org/uniprot/A0A386HGY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0394 family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS11085 ^@ http://purl.uniprot.org/uniprot/A0A8D4SQY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS18575 ^@ http://purl.uniprot.org/uniprot/A0A386HIW0 ^@ Cofactor ^@ Can also use Mn(2+) ion. http://togogenome.org/gene/1604335:DXZ79_RS16335 ^@ http://purl.uniprot.org/uniprot/A0A386HIA6 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. http://togogenome.org/gene/1604335:DXZ79_RS07745 ^@ http://purl.uniprot.org/uniprot/A0A386HD64 ^@ Similarity ^@ Belongs to the UPF0265 family. http://togogenome.org/gene/1604335:DXZ79_RS05690 ^@ http://purl.uniprot.org/uniprot/A0A386HC99 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/1604335:DXZ79_RS04985 ^@ http://purl.uniprot.org/uniprot/A0A386HBI2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1604335:DXZ79_RS14145 ^@ http://purl.uniprot.org/uniprot/A0A8D4SNU1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS13695 ^@ http://purl.uniprot.org/uniprot/A0A386HFM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS16340 ^@ http://purl.uniprot.org/uniprot/A0A386HHG9 ^@ Similarity ^@ Belongs to the agmatine deiminase family. http://togogenome.org/gene/1604335:DXZ79_RS09800 ^@ http://purl.uniprot.org/uniprot/A0A386HER8 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1604335:DXZ79_RS19470 ^@ http://purl.uniprot.org/uniprot/A0A386HIY3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S54 family.|||Cell membrane|||Membrane|||Rhomboid-type serine protease that catalyzes intramembrane proteolysis. http://togogenome.org/gene/1604335:DXZ79_RS17325 ^@ http://purl.uniprot.org/uniprot/A0A8D4N371 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1604335:DXZ79_RS09780 ^@ http://purl.uniprot.org/uniprot/A0A386HED0 ^@ Cofactor|||Similarity ^@ Belongs to the nitroreductase family.|||Binds 1 FMN per subunit. http://togogenome.org/gene/1604335:DXZ79_RS16600 ^@ http://purl.uniprot.org/uniprot/A0A386HH66 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/1604335:DXZ79_RS03785 ^@ http://purl.uniprot.org/uniprot/A0A386HBC2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/1604335:DXZ79_RS07450 ^@ http://purl.uniprot.org/uniprot/A0A386HD44 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 2 family.|||Periplasm|||The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB). http://togogenome.org/gene/1604335:DXZ79_RS13200 ^@ http://purl.uniprot.org/uniprot/A0A386HFV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS17040 ^@ http://purl.uniprot.org/uniprot/A0A8D4SRW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS10070 ^@ http://purl.uniprot.org/uniprot/A0A386HE13 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1604335:DXZ79_RS16725 ^@ http://purl.uniprot.org/uniprot/A0A386HIG5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS19230 ^@ http://purl.uniprot.org/uniprot/A0A386HIT9 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/1604335:DXZ79_RS18095 ^@ http://purl.uniprot.org/uniprot/A0A386HIL3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.|||Cell membrane|||Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS07060 ^@ http://purl.uniprot.org/uniprot/A0A386HCK2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/1604335:DXZ79_RS12040 ^@ http://purl.uniprot.org/uniprot/A0A386HEY2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs.|||Cytoplasm|||Interacts with TusE. http://togogenome.org/gene/1604335:DXZ79_RS09915 ^@ http://purl.uniprot.org/uniprot/A0A386HDX7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.|||Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS10550 ^@ http://purl.uniprot.org/uniprot/A0A386HES4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS17275 ^@ http://purl.uniprot.org/uniprot/A0A386HIR2 ^@ Domain|||Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/1604335:DXZ79_RS10405 ^@ http://purl.uniprot.org/uniprot/A0A386HEU0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS13805 ^@ http://purl.uniprot.org/uniprot/A0A386HFP8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion system.|||Belongs to the flk family.|||Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS05500 ^@ http://purl.uniprot.org/uniprot/A0A386HBN6 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS14220 ^@ http://purl.uniprot.org/uniprot/A0A386HGD1 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/1604335:DXZ79_RS02435 ^@ http://purl.uniprot.org/uniprot/A0A386HAB5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS15120 ^@ http://purl.uniprot.org/uniprot/A0A386HGV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS20440 ^@ http://purl.uniprot.org/uniprot/A0A386HJE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS03755 ^@ http://purl.uniprot.org/uniprot/A0A386HAT7 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1604335:DXZ79_RS01245 ^@ http://purl.uniprot.org/uniprot/A0A386H9T2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PanZ/PanM family.|||Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion.|||Interacts with PanD in the presence of CoA. http://togogenome.org/gene/1604335:DXZ79_RS18680 ^@ http://purl.uniprot.org/uniprot/A0A386HIN1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/1604335:DXZ79_RS15050 ^@ http://purl.uniprot.org/uniprot/A0A386HGD5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RdgC family.|||May be involved in recombination.|||nucleoid http://togogenome.org/gene/1604335:DXZ79_RS12945 ^@ http://purl.uniprot.org/uniprot/A0A8E4BJQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS11775 ^@ http://purl.uniprot.org/uniprot/A0A386HFC3 ^@ Similarity ^@ Belongs to the UPF0181 family. http://togogenome.org/gene/1604335:DXZ79_RS12515 ^@ http://purl.uniprot.org/uniprot/A0A386HFQ1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.|||Cell outer membrane|||Membrane|||Monomer and homodimer.|||The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins.|||With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. http://togogenome.org/gene/1604335:DXZ79_RS20510 ^@ http://purl.uniprot.org/uniprot/A0A386HIY9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1604335:DXZ79_RS10525 ^@ http://purl.uniprot.org/uniprot/A0A386HEW3 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/1604335:DXZ79_RS12900 ^@ http://purl.uniprot.org/uniprot/A0A8E4BML1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS07685 ^@ http://purl.uniprot.org/uniprot/A0A386HD47 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS10910 ^@ http://purl.uniprot.org/uniprot/A0A386HF04 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS11080 ^@ http://purl.uniprot.org/uniprot/A0A386HF38 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS01440 ^@ http://purl.uniprot.org/uniprot/A0A8D4N3A8 ^@ Function|||Similarity|||Subunit ^@ Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).|||In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.|||In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.|||Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. http://togogenome.org/gene/1604335:DXZ79_RS04520 ^@ http://purl.uniprot.org/uniprot/A0A386HBV7 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS18060 ^@ http://purl.uniprot.org/uniprot/A0A386HKD2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Rnk family.|||Interacts with the RNA polymerase.|||May act as an anti-Gre factor. http://togogenome.org/gene/1604335:DXZ79_RS00575 ^@ http://purl.uniprot.org/uniprot/A0A386H9Y2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS10345 ^@ http://purl.uniprot.org/uniprot/A0A8D4SRY5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS18185 ^@ http://purl.uniprot.org/uniprot/A0A386HHT8 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1604335:DXZ79_RS00060 ^@ http://purl.uniprot.org/uniprot/A0A386H926 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/1604335:DXZ79_RS13405 ^@ http://purl.uniprot.org/uniprot/A0A386HG37 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the protease inhibitor I11 (ecotin) family.|||General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.|||Homodimer.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS03520 ^@ http://purl.uniprot.org/uniprot/A0A386HB74 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1604335:DXZ79_RS19265 ^@ http://purl.uniprot.org/uniprot/A0A386HJ18 ^@ Function|||Similarity ^@ Belongs to the precorrin methyltransferase family.|||In the C-terminal section; belongs to the precorrin methyltransferase family.|||In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.|||Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. http://togogenome.org/gene/1604335:DXZ79_RS05110 ^@ http://purl.uniprot.org/uniprot/A0A8D4N009 ^@ Similarity ^@ Belongs to the UPF0125 (RnfH) family. http://togogenome.org/gene/1604335:DXZ79_RS16980 ^@ http://purl.uniprot.org/uniprot/A0A386HI24 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS18930 ^@ http://purl.uniprot.org/uniprot/A0A386HIV7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1604335:DXZ79_RS05680 ^@ http://purl.uniprot.org/uniprot/A0A386HCG4 ^@ Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. http://togogenome.org/gene/1604335:DXZ79_RS08615 ^@ http://purl.uniprot.org/uniprot/A0A386HDH3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1604335:DXZ79_RS05715 ^@ http://purl.uniprot.org/uniprot/A0A386HCJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS07995 ^@ http://purl.uniprot.org/uniprot/A0A8D4N4J7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS02590 ^@ http://purl.uniprot.org/uniprot/A0A8D4N251 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS18070 ^@ http://purl.uniprot.org/uniprot/A0A386HII8 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1604335:DXZ79_RS12215 ^@ http://purl.uniprot.org/uniprot/A0A386HF93 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/1604335:DXZ79_RS09090 ^@ http://purl.uniprot.org/uniprot/A0A386HE50 ^@ Similarity ^@ Belongs to the UPF0423 family. http://togogenome.org/gene/1604335:DXZ79_RS18075 ^@ http://purl.uniprot.org/uniprot/A0A386HHS5 ^@ Similarity ^@ Belongs to the UPF0307 family. http://togogenome.org/gene/1604335:DXZ79_RS00525 ^@ http://purl.uniprot.org/uniprot/A0A386H9L8 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/1604335:DXZ79_RS00785 ^@ http://purl.uniprot.org/uniprot/A0A8D4MYQ7 ^@ Similarity ^@ Belongs to the UPF0438 family. http://togogenome.org/gene/1604335:DXZ79_RS11065 ^@ http://purl.uniprot.org/uniprot/A0A386HEB6 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems.|||Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/1604335:DXZ79_RS01250 ^@ http://purl.uniprot.org/uniprot/A0A386HA78 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/1604335:DXZ79_RS05695 ^@ http://purl.uniprot.org/uniprot/A0A386HCN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS09615 ^@ http://purl.uniprot.org/uniprot/A0A386HEA0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase D family.|||Cytoplasm|||Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides. http://togogenome.org/gene/1604335:DXZ79_RS15570 ^@ http://purl.uniprot.org/uniprot/A0A386HH36 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/1604335:DXZ79_RS13150 ^@ http://purl.uniprot.org/uniprot/A0A386HFZ8 ^@ Function|||Similarity ^@ Belongs to the mannonate dehydratase family.|||Catalyzes the dehydration of D-mannonate. http://togogenome.org/gene/1604335:DXZ79_RS17870 ^@ http://purl.uniprot.org/uniprot/A0A8E4BMK2 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/1604335:DXZ79_RS13115 ^@ http://purl.uniprot.org/uniprot/A0A386HG50 ^@ Function|||Similarity ^@ Belongs to the carbohydrate kinase PfkB family.|||Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate. http://togogenome.org/gene/1604335:DXZ79_RS14195 ^@ http://purl.uniprot.org/uniprot/A0A386HFW6 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/1604335:DXZ79_RS03745 ^@ http://purl.uniprot.org/uniprot/A0A386HB54 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS10260 ^@ http://purl.uniprot.org/uniprot/A0A386HEH3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1604335:DXZ79_RS16880 ^@ http://purl.uniprot.org/uniprot/A0A386HI03 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/1604335:DXZ79_RS12510 ^@ http://purl.uniprot.org/uniprot/A0A386HF45 ^@ Function|||Induction|||PTM|||Similarity|||Subunit ^@ Belongs to the SulA family.|||By DNA damage, as part of the SOS response.|||Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.|||Interacts with FtsZ.|||Is rapidly cleaved and degraded by the Lon protease once DNA damage is repaired. http://togogenome.org/gene/1604335:DXZ79_RS19815 ^@ http://purl.uniprot.org/uniprot/A0A386HJZ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Cell membrane|||Membrane|||Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. http://togogenome.org/gene/1604335:DXZ79_RS04060 ^@ http://purl.uniprot.org/uniprot/A0A386HBM8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/1604335:DXZ79_RS09510 ^@ http://purl.uniprot.org/uniprot/A0A386HE72 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/1604335:DXZ79_RS07320 ^@ http://purl.uniprot.org/uniprot/A0A386HD16 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Dps family.|||Cytoplasm|||During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.|||Homododecamer. The 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited. http://togogenome.org/gene/1604335:DXZ79_RS18935 ^@ http://purl.uniprot.org/uniprot/A0A386HJ16 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1604335:DXZ79_RS18090 ^@ http://purl.uniprot.org/uniprot/A0A386HIH6 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1604335:DXZ79_RS16360 ^@ http://purl.uniprot.org/uniprot/A0A386HH00 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/1604335:DXZ79_RS04500 ^@ http://purl.uniprot.org/uniprot/A0A386HB89 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS05305 ^@ http://purl.uniprot.org/uniprot/A0A386HBT5 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1604335:DXZ79_RS08705 ^@ http://purl.uniprot.org/uniprot/A0A386HDS5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Flagellar protein that affects chemotactic events.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS05220 ^@ http://purl.uniprot.org/uniprot/A0A386HBM0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers. http://togogenome.org/gene/1604335:DXZ79_RS02640 ^@ http://purl.uniprot.org/uniprot/A0A8D4MZA4 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/1604335:DXZ79_RS01445 ^@ http://purl.uniprot.org/uniprot/A0A386HAI5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.|||Binds 2 manganese ions per subunit.|||Splits dipeptides with a prolyl residue in the C-terminal position. http://togogenome.org/gene/1604335:DXZ79_RS01115 ^@ http://purl.uniprot.org/uniprot/A0A386H9K2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phospholipase A1 family.|||Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.|||Cell outer membrane|||Homodimer; dimerization is reversible, and the dimeric form is the active one.|||Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS14845 ^@ http://purl.uniprot.org/uniprot/A0A386HG80 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heme-copper respiratory oxidase family.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS07520 ^@ http://purl.uniprot.org/uniprot/A0A386HCT1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS19160 ^@ http://purl.uniprot.org/uniprot/A0A386HJ64 ^@ Similarity ^@ Belongs to the PhzF family. http://togogenome.org/gene/1604335:DXZ79_RS01585 ^@ http://purl.uniprot.org/uniprot/A0A386HA33 ^@ Similarity ^@ Belongs to the MxiH/PrgI/YscF family. http://togogenome.org/gene/1604335:DXZ79_RS15185 ^@ http://purl.uniprot.org/uniprot/A0A386HGD6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS13750 ^@ http://purl.uniprot.org/uniprot/A0A386HFN6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS04355 ^@ http://purl.uniprot.org/uniprot/A0A8D4MXX8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS04595 ^@ http://purl.uniprot.org/uniprot/A0A386HBK5 ^@ Function|||Similarity ^@ Belongs to the TorD/DmsD family. DmsD subfamily.|||Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding-maturation pathway for the substrate protein. http://togogenome.org/gene/1604335:DXZ79_RS00375 ^@ http://purl.uniprot.org/uniprot/A0A386H973 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS02595 ^@ http://purl.uniprot.org/uniprot/A0A386HAX8 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/1604335:DXZ79_RS09210 ^@ http://purl.uniprot.org/uniprot/A0A386HEE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS04865 ^@ http://purl.uniprot.org/uniprot/A0A8D4SRF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS10140 ^@ http://purl.uniprot.org/uniprot/A0A386HEN8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LapB family.|||Cell inner membrane|||Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane. http://togogenome.org/gene/1604335:DXZ79_RS03890 ^@ http://purl.uniprot.org/uniprot/A0A386HB28 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS03575 ^@ http://purl.uniprot.org/uniprot/A0A386HB84 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/1604335:DXZ79_RS03640 ^@ http://purl.uniprot.org/uniprot/A0A386HB36 ^@ Domain|||Function|||Subcellular Location Annotation ^@ Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.|||Periplasm|||The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition. http://togogenome.org/gene/1604335:DXZ79_RS19845 ^@ http://purl.uniprot.org/uniprot/A0A386HIK9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 8 (cellulase D) family. http://togogenome.org/gene/1604335:DXZ79_RS14960 ^@ http://purl.uniprot.org/uniprot/A0A386HGA3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/1604335:DXZ79_RS17940 ^@ http://purl.uniprot.org/uniprot/A0A386HI90 ^@ Function|||Similarity ^@ Belongs to the sigma-54 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1604335:DXZ79_RS08675 ^@ http://purl.uniprot.org/uniprot/A0A386HDI6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/1604335:DXZ79_RS04295 ^@ http://purl.uniprot.org/uniprot/A0A386HBR8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS14745 ^@ http://purl.uniprot.org/uniprot/A0A386HG60 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS08545 ^@ http://purl.uniprot.org/uniprot/A0A386HDP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS17240 ^@ http://purl.uniprot.org/uniprot/A0A386HHD9 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1604335:DXZ79_RS10185 ^@ http://purl.uniprot.org/uniprot/A0A386HEL0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS00650 ^@ http://purl.uniprot.org/uniprot/A0A8D4N0X2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm|||In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily. http://togogenome.org/gene/1604335:DXZ79_RS04255 ^@ http://purl.uniprot.org/uniprot/A0A386HBT2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS08710 ^@ http://purl.uniprot.org/uniprot/A0A386HK21 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS10505 ^@ http://purl.uniprot.org/uniprot/A0A386HEQ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS11875 ^@ http://purl.uniprot.org/uniprot/A0A386HF29 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS00710 ^@ http://purl.uniprot.org/uniprot/A0A386H9V1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS11105 ^@ http://purl.uniprot.org/uniprot/A0A386HFE7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.|||Cell inner membrane|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Multidrug efflux pump that functions probably as a Na(+)/drug antiporter. http://togogenome.org/gene/1604335:DXZ79_RS15680 ^@ http://purl.uniprot.org/uniprot/A0A386HGM9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Xni family.|||Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.|||Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.|||Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. http://togogenome.org/gene/1604335:DXZ79_RS09845 ^@ http://purl.uniprot.org/uniprot/A0A386HEE4 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the RssB family.|||Binds to RpoS.|||Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.|||Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. http://togogenome.org/gene/1604335:DXZ79_RS09570 ^@ http://purl.uniprot.org/uniprot/A0A386HDS6 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS06450 ^@ http://purl.uniprot.org/uniprot/A0A386HCU7 ^@ Function|||Similarity ^@ Belongs to the IUNH family. RihA subfamily.|||Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively. http://togogenome.org/gene/1604335:DXZ79_RS20100 ^@ http://purl.uniprot.org/uniprot/A0A386HJR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the periplasmic pilus chaperone family.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS14165 ^@ http://purl.uniprot.org/uniprot/A0A386HGC3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS08300 ^@ http://purl.uniprot.org/uniprot/A0A8D4SRY0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS06925 ^@ http://purl.uniprot.org/uniprot/A0A386HCC0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS09230 ^@ http://purl.uniprot.org/uniprot/A0A386HDG1 ^@ Function|||Similarity ^@ Belongs to the aldehyde dehydrogenase family. AstD subfamily.|||Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate. http://togogenome.org/gene/1604335:DXZ79_RS13670 ^@ http://purl.uniprot.org/uniprot/A0A386HGY2 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1604335:DXZ79_RS04715 ^@ http://purl.uniprot.org/uniprot/A0A386HC11 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.|||Cell inner membrane|||Membrane|||Responsible for the transport of C4-dicarboxylates. http://togogenome.org/gene/1604335:DXZ79_RS17715 ^@ http://purl.uniprot.org/uniprot/A0A386HIY8 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/1604335:DXZ79_RS13315 ^@ http://purl.uniprot.org/uniprot/A0A386HFX3 ^@ Similarity ^@ Belongs to the sodium:galactoside symporter (TC 2.A.2) family. http://togogenome.org/gene/1604335:DXZ79_RS01210 ^@ http://purl.uniprot.org/uniprot/A0A386H9J2 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. RsmD family.|||Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle. http://togogenome.org/gene/1604335:DXZ79_RS03310 ^@ http://purl.uniprot.org/uniprot/A0A8D4MZU3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methyltransferase superfamily. RsmC family.|||Cytoplasm|||Monomer.|||Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle. http://togogenome.org/gene/1604335:DXZ79_RS17150 ^@ http://purl.uniprot.org/uniprot/A0A386HIB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS04515 ^@ http://purl.uniprot.org/uniprot/A0A386HBP9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1604335:DXZ79_RS14135 ^@ http://purl.uniprot.org/uniprot/A0A386HFV8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS12200 ^@ http://purl.uniprot.org/uniprot/A0A386HF07 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/1604335:DXZ79_RS07065 ^@ http://purl.uniprot.org/uniprot/A0A8D4MYN9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/1604335:DXZ79_RS13560 ^@ http://purl.uniprot.org/uniprot/A0A386HG66 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/1604335:DXZ79_RS18730 ^@ http://purl.uniprot.org/uniprot/A0A386HIP1 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1604335:DXZ79_RS03410 ^@ http://purl.uniprot.org/uniprot/A0A386HBE7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS03435 ^@ http://purl.uniprot.org/uniprot/A0A386HBC9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the YjjX NTPase family.|||Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).|||Homodimer.|||Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/1604335:DXZ79_RS09470 ^@ http://purl.uniprot.org/uniprot/A0A8D4N512 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.|||Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS06690 ^@ http://purl.uniprot.org/uniprot/A0A8D4SRB7 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/1604335:DXZ79_RS11795 ^@ http://purl.uniprot.org/uniprot/A0A386HFD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heat-stable enterotoxin family.|||Secreted http://togogenome.org/gene/1604335:DXZ79_RS12665 ^@ http://purl.uniprot.org/uniprot/A0A386HF67 ^@ Similarity ^@ Belongs to the fructosamine kinase family. http://togogenome.org/gene/1604335:DXZ79_RS05020 ^@ http://purl.uniprot.org/uniprot/A0A386HC61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the urea transporter family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS05750 ^@ http://purl.uniprot.org/uniprot/A0A386HCB2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0756 family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS19775 ^@ http://purl.uniprot.org/uniprot/A0A8D4N8G1 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1604335:DXZ79_RS02195 ^@ http://purl.uniprot.org/uniprot/A0A386HAK4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/1604335:DXZ79_RS08020 ^@ http://purl.uniprot.org/uniprot/A0A386HD12 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/1604335:DXZ79_RS18065 ^@ http://purl.uniprot.org/uniprot/A0A386HIB7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the cytochrome b562 family.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per molecule.|||Electron-transport protein of unknown function. http://togogenome.org/gene/1604335:DXZ79_RS03875 ^@ http://purl.uniprot.org/uniprot/A0A386HBL0 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1604335:DXZ79_RS11820 ^@ http://purl.uniprot.org/uniprot/A0A386HFY1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0266 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS10605 ^@ http://purl.uniprot.org/uniprot/A0A386HF53 ^@ Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Dimer of large and small chains. http://togogenome.org/gene/1604335:DXZ79_RS11425 ^@ http://purl.uniprot.org/uniprot/A0A386HFS8 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/1604335:DXZ79_RS08130 ^@ http://purl.uniprot.org/uniprot/A0A8D4SRK8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS12375 ^@ http://purl.uniprot.org/uniprot/A0A8D4SNJ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acyltransferase 3 family. OpgC subfamily.|||Cell membrane|||Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane. http://togogenome.org/gene/1604335:DXZ79_RS08200 ^@ http://purl.uniprot.org/uniprot/A0A8D4N0X3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/1604335:DXZ79_RS20170 ^@ http://purl.uniprot.org/uniprot/A0A386HK51 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems.|||Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/1604335:DXZ79_RS07545 ^@ http://purl.uniprot.org/uniprot/A0A386HCM8 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/1604335:DXZ79_RS09545 ^@ http://purl.uniprot.org/uniprot/A0A386HDM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M23B family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS05935 ^@ http://purl.uniprot.org/uniprot/A0A386HCN8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.|||Catalyzes the proton-dependent transport of sialic acid.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS11010 ^@ http://purl.uniprot.org/uniprot/A0A8D4N1T7 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1604335:DXZ79_RS00495 ^@ http://purl.uniprot.org/uniprot/A0A386HA26 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1604335:DXZ79_RS15645 ^@ http://purl.uniprot.org/uniprot/A0A386HHE2 ^@ Similarity ^@ Belongs to the UPF0325 family. http://togogenome.org/gene/1604335:DXZ79_RS12520 ^@ http://purl.uniprot.org/uniprot/A0A386HFV2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MatP family.|||Cytoplasm|||Homodimer.|||Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain. http://togogenome.org/gene/1604335:DXZ79_RS02570 ^@ http://purl.uniprot.org/uniprot/A0A386HAQ4 ^@ Similarity ^@ Belongs to the peptidase S13 family. http://togogenome.org/gene/1604335:DXZ79_RS16970 ^@ http://purl.uniprot.org/uniprot/A0A386HHA2 ^@ Function|||Similarity ^@ Belongs to the FlgN family.|||Required for the efficient initiation of filament assembly. http://togogenome.org/gene/1604335:DXZ79_RS10970 ^@ http://purl.uniprot.org/uniprot/A0A386HF47 ^@ Function|||Similarity|||Subunit ^@ Belongs to the pyridoxine kinase family. PdxY subfamily.|||Homodimer.|||Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. http://togogenome.org/gene/1604335:DXZ79_RS16815 ^@ http://purl.uniprot.org/uniprot/A0A386HH64 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.|||Cell membrane|||Heterodimer of a large and a small subunit. http://togogenome.org/gene/1604335:DXZ79_RS19445 ^@ http://purl.uniprot.org/uniprot/A0A386HJB1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NfuA family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.|||Homodimer.|||Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. http://togogenome.org/gene/1604335:DXZ79_RS07120 ^@ http://purl.uniprot.org/uniprot/A0A386HCU6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. RhlE subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA. http://togogenome.org/gene/1604335:DXZ79_RS11790 ^@ http://purl.uniprot.org/uniprot/A0A386HES7 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/1604335:DXZ79_RS12405 ^@ http://purl.uniprot.org/uniprot/A0A386HFR8 ^@ Function|||Similarity ^@ Belongs to the CcmH/CycL/Ccl2/NrfF family.|||Possible subunit of a heme lyase. http://togogenome.org/gene/1604335:DXZ79_RS00540 ^@ http://purl.uniprot.org/uniprot/A0A386H9A3 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Activity of this regulatory enzyme is affected by several metabolites. Allosterically and non-competitively inhibited by fructose 1,6-bisphosphate (FBP) and unphosphorylated phosphocarrier protein EIIA-Glc (III-Glc), an integral component of the bacterial phosphotransferase (PTS) system.|||Belongs to the FGGY kinase family.|||Homotetramer and homodimer (in equilibrium). Heterodimer with EIIA-Glc. Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/1604335:DXZ79_RS13665 ^@ http://purl.uniprot.org/uniprot/A0A386HG34 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS12075 ^@ http://purl.uniprot.org/uniprot/A0A386HFH7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20B family.|||Binds 2 Zn(2+) ions per subunit.|||Cleaves the N-terminal amino acid of tripeptides.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS15285 ^@ http://purl.uniprot.org/uniprot/A0A386HGF6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/1604335:DXZ79_RS16245 ^@ http://purl.uniprot.org/uniprot/A0A386HGX2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/1604335:DXZ79_RS04290 ^@ http://purl.uniprot.org/uniprot/A0A386HBK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS02355 ^@ http://purl.uniprot.org/uniprot/A0A386HA20 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1604335:DXZ79_RS09060 ^@ http://purl.uniprot.org/uniprot/A0A386HDP6 ^@ Similarity ^@ Belongs to the hyi family. http://togogenome.org/gene/1604335:DXZ79_RS00165 ^@ http://purl.uniprot.org/uniprot/A0A386H9A8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS03145 ^@ http://purl.uniprot.org/uniprot/A0A386HB77 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 2 family.|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases.|||Periplasm|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/1604335:DXZ79_RS02130 ^@ http://purl.uniprot.org/uniprot/A0A386H9Y0 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/1604335:DXZ79_RS17650 ^@ http://purl.uniprot.org/uniprot/A0A386HI42 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. http://togogenome.org/gene/1604335:DXZ79_RS00835 ^@ http://purl.uniprot.org/uniprot/A0A386HA11 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS17095 ^@ http://purl.uniprot.org/uniprot/A0A386HI44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS15125 ^@ http://purl.uniprot.org/uniprot/A0A386HGZ9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pseudouridine-5'-phosphate glycosidase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.|||Homotrimer. http://togogenome.org/gene/1604335:DXZ79_RS06985 ^@ http://purl.uniprot.org/uniprot/A0A386HD22 ^@ Similarity ^@ Belongs to the ModE family. http://togogenome.org/gene/1604335:DXZ79_RS03155 ^@ http://purl.uniprot.org/uniprot/A0A8D4MXJ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/1604335:DXZ79_RS07790 ^@ http://purl.uniprot.org/uniprot/A0A386HDA9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetokinase family. PduW subfamily.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS06360 ^@ http://purl.uniprot.org/uniprot/A0A386HCY6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS15630 ^@ http://purl.uniprot.org/uniprot/A0A386HGL9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1604335:DXZ79_RS03650 ^@ http://purl.uniprot.org/uniprot/A0A386HAR5 ^@ Domain|||Function|||Subcellular Location Annotation|||Subunit ^@ Cell inner membrane|||Homodimer.|||Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.|||The transmembrane domain is a dimerization domain. http://togogenome.org/gene/1604335:DXZ79_RS14895 ^@ http://purl.uniprot.org/uniprot/A0A386HGU8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1604335:DXZ79_RS16985 ^@ http://purl.uniprot.org/uniprot/A0A386HI84 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliH family.|||Cytoplasm|||Needed for flagellar regrowth and assembly. http://togogenome.org/gene/1604335:DXZ79_RS18385 ^@ http://purl.uniprot.org/uniprot/A0A386HHX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS20445 ^@ http://purl.uniprot.org/uniprot/A0A386HKA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS04560 ^@ http://purl.uniprot.org/uniprot/A0A386HBX8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/1604335:DXZ79_RS16115 ^@ http://purl.uniprot.org/uniprot/A0A8D4N850 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS07980 ^@ http://purl.uniprot.org/uniprot/A0A8D4N3S1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Part of an ABC transporter complex. Responsible for energy coupling to the transport system. http://togogenome.org/gene/1604335:DXZ79_RS03830 ^@ http://purl.uniprot.org/uniprot/A0A8E3ZHN8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS18840 ^@ http://purl.uniprot.org/uniprot/A0A8E3ZHZ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family. TsaC subfamily.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. http://togogenome.org/gene/1604335:DXZ79_RS17775 ^@ http://purl.uniprot.org/uniprot/A0A386HIZ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS05100 ^@ http://purl.uniprot.org/uniprot/A0A386HJN7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1604335:DXZ79_RS08575 ^@ http://purl.uniprot.org/uniprot/A0A386HD68 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1604335:DXZ79_RS13380 ^@ http://purl.uniprot.org/uniprot/A0A386HFY2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1604335:DXZ79_RS12770 ^@ http://purl.uniprot.org/uniprot/A0A386HFV4 ^@ Function|||Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.|||DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes. http://togogenome.org/gene/1604335:DXZ79_RS07455 ^@ http://purl.uniprot.org/uniprot/A0A386HDF9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.|||Cell inner membrane|||Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.|||The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB). http://togogenome.org/gene/1604335:DXZ79_RS14525 ^@ http://purl.uniprot.org/uniprot/A0A386HG22 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS12980 ^@ http://purl.uniprot.org/uniprot/A0A386HF98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS05685 ^@ http://purl.uniprot.org/uniprot/A0A386HKL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS04900 ^@ http://purl.uniprot.org/uniprot/A0A386HBL3 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1604335:DXZ79_RS11220 ^@ http://purl.uniprot.org/uniprot/A0A386HFA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/1604335:DXZ79_RS08145 ^@ http://purl.uniprot.org/uniprot/A0A8D4N2H4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the P-Pant transferase superfamily. EntD family.|||EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.|||Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively. http://togogenome.org/gene/1604335:DXZ79_RS06930 ^@ http://purl.uniprot.org/uniprot/A0A386HCA8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane|||Required for nicotinamide riboside transport across the inner membrane. http://togogenome.org/gene/1604335:DXZ79_RS14840 ^@ http://purl.uniprot.org/uniprot/A0A386HGT8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Cell membrane|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS07415 ^@ http://purl.uniprot.org/uniprot/A0A386HDF1 ^@ Function|||Similarity ^@ Belongs to the esterase D family.|||Serine hydrolase involved in the detoxification of formaldehyde. http://togogenome.org/gene/1604335:DXZ79_RS07090 ^@ http://purl.uniprot.org/uniprot/A0A386HCF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS08070 ^@ http://purl.uniprot.org/uniprot/A0A386HDG2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS10650 ^@ http://purl.uniprot.org/uniprot/A0A386HE98 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/1604335:DXZ79_RS03535 ^@ http://purl.uniprot.org/uniprot/A0A386HB55 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1604335:DXZ79_RS04035 ^@ http://purl.uniprot.org/uniprot/A0A386HBE8 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/1604335:DXZ79_RS08210 ^@ http://purl.uniprot.org/uniprot/A0A8D4SRL2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS12345 ^@ http://purl.uniprot.org/uniprot/A0A386HJX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS18465 ^@ http://purl.uniprot.org/uniprot/A0A386HIB2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/1604335:DXZ79_RS11340 ^@ http://purl.uniprot.org/uniprot/A0A386HF11 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS03825 ^@ http://purl.uniprot.org/uniprot/A0A386HBC5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II). http://togogenome.org/gene/1604335:DXZ79_RS01255 ^@ http://purl.uniprot.org/uniprot/A0A386HAF3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/1604335:DXZ79_RS13050 ^@ http://purl.uniprot.org/uniprot/A0A386HFZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS15600 ^@ http://purl.uniprot.org/uniprot/A0A386HHI8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS06800 ^@ http://purl.uniprot.org/uniprot/A0A386HD65 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbB/TolQ family.|||Cell inner membrane|||Membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/1604335:DXZ79_RS05355 ^@ http://purl.uniprot.org/uniprot/A0A386HBU5 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/1604335:DXZ79_RS04310 ^@ http://purl.uniprot.org/uniprot/A0A386HBU0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsB family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/1604335:DXZ79_RS04070 ^@ http://purl.uniprot.org/uniprot/A0A386HBH6 ^@ Function|||Similarity ^@ Belongs to the HPPK family.|||Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway. http://togogenome.org/gene/1604335:DXZ79_RS06780 ^@ http://purl.uniprot.org/uniprot/A0A386HCB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS03580 ^@ http://purl.uniprot.org/uniprot/A0A386HBH3 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/1604335:DXZ79_RS00865 ^@ http://purl.uniprot.org/uniprot/A0A386H9S0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the periplasmic pilus chaperone family.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS09235 ^@ http://purl.uniprot.org/uniprot/A0A386HE27 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinylarginine dihydrolase family.|||Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS13385 ^@ http://purl.uniprot.org/uniprot/A0A386HKV1 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. UbiG/COQ3 family.|||O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. http://togogenome.org/gene/1604335:DXZ79_RS12485 ^@ http://purl.uniprot.org/uniprot/A0A386HFJ4 ^@ Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. http://togogenome.org/gene/1604335:DXZ79_RS17390 ^@ http://purl.uniprot.org/uniprot/A0A386HIT4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS00565 ^@ http://purl.uniprot.org/uniprot/A0A386H9X3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RraA family.|||Cytoplasm|||Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.|||Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB. http://togogenome.org/gene/1604335:DXZ79_RS00145 ^@ http://purl.uniprot.org/uniprot/A0A386H9X2 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/1604335:DXZ79_RS03720 ^@ http://purl.uniprot.org/uniprot/A0A386HBA5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1604335:DXZ79_RS07880 ^@ http://purl.uniprot.org/uniprot/A0A386HCU3 ^@ Subcellular Location Annotation ^@ Bacterial microcompartment http://togogenome.org/gene/1604335:DXZ79_RS00050 ^@ http://purl.uniprot.org/uniprot/A0A386H9F1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbsD / FucU family. RbsD subfamily.|||Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.|||Cytoplasm|||Homodecamer. http://togogenome.org/gene/1604335:DXZ79_RS05625 ^@ http://purl.uniprot.org/uniprot/A0A386HCF6 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1604335:DXZ79_RS13700 ^@ http://purl.uniprot.org/uniprot/A0A386HGA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS08315 ^@ http://purl.uniprot.org/uniprot/A0A386HD58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS17560 ^@ http://purl.uniprot.org/uniprot/A0A8D4N4L1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS15550 ^@ http://purl.uniprot.org/uniprot/A0A8E4GYB3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS15335 ^@ http://purl.uniprot.org/uniprot/A0A386HGG7 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/1604335:DXZ79_RS03790 ^@ http://purl.uniprot.org/uniprot/A0A386HBK9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsL family.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.|||Membrane|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/1604335:DXZ79_RS17125 ^@ http://purl.uniprot.org/uniprot/A0A8D4SRW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/1604335:DXZ79_RS15320 ^@ http://purl.uniprot.org/uniprot/A0A386HHR7 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||Homotetramer.|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/1604335:DXZ79_RS14060 ^@ http://purl.uniprot.org/uniprot/A0A386HFU6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmD/CycX/HelD family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/1604335:DXZ79_RS18105 ^@ http://purl.uniprot.org/uniprot/A0A386HI51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AaeX family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS00185 ^@ http://purl.uniprot.org/uniprot/A0A386H9G6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons. http://togogenome.org/gene/1604335:DXZ79_RS08320 ^@ http://purl.uniprot.org/uniprot/A0A386HDE9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1604335:DXZ79_RS05540 ^@ http://purl.uniprot.org/uniprot/A0A386HC19 ^@ Similarity|||Subunit ^@ Belongs to the SIS family. GutQ/KpsF subfamily.|||Homotetramer. http://togogenome.org/gene/1604335:DXZ79_RS18455 ^@ http://purl.uniprot.org/uniprot/A0A386HKR8 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1604335:DXZ79_RS16485 ^@ http://purl.uniprot.org/uniprot/A0A8D4N6L5 ^@ Similarity ^@ Belongs to the transposase 8 family. http://togogenome.org/gene/1604335:DXZ79_RS17805 ^@ http://purl.uniprot.org/uniprot/A0A386HHM6 ^@ Function|||Similarity ^@ Belongs to the peptidase C56 family.|||Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate. http://togogenome.org/gene/1604335:DXZ79_RS17355 ^@ http://purl.uniprot.org/uniprot/A0A386HI47 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS11860 ^@ http://purl.uniprot.org/uniprot/A0A386HEV2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS20225 ^@ http://purl.uniprot.org/uniprot/A0A386HJA5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1604335:DXZ79_RS12995 ^@ http://purl.uniprot.org/uniprot/A0A386HFY8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS08620 ^@ http://purl.uniprot.org/uniprot/A0A386HDS1 ^@ Function|||Similarity ^@ Belongs to the FlgD family.|||Required for flagellar hook formation. May act as a scaffolding protein. http://togogenome.org/gene/1604335:DXZ79_RS05465 ^@ http://purl.uniprot.org/uniprot/A0A386HCJ4 ^@ Similarity ^@ Belongs to the YfgM family. http://togogenome.org/gene/1604335:DXZ79_RS13570 ^@ http://purl.uniprot.org/uniprot/A0A8D4N548 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/1604335:DXZ79_RS05600 ^@ http://purl.uniprot.org/uniprot/A0A386HC78 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtC forms a heteromultimer with MdtB. http://togogenome.org/gene/1604335:DXZ79_RS06595 ^@ http://purl.uniprot.org/uniprot/A0A386HCD6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS11570 ^@ http://purl.uniprot.org/uniprot/A0A386HF90 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PqiA family.|||Component of a transport pathway that contributes to membrane integrity.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS02220 ^@ http://purl.uniprot.org/uniprot/A0A386HAX4 ^@ Similarity ^@ Belongs to the EcnA/EcnB lipoprotein family. http://togogenome.org/gene/1604335:DXZ79_RS01060 ^@ http://purl.uniprot.org/uniprot/A0A386H9G7 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.|||FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the top DNA strands. http://togogenome.org/gene/1604335:DXZ79_RS08655 ^@ http://purl.uniprot.org/uniprot/A0A8D4N2P1 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/1604335:DXZ79_RS13710 ^@ http://purl.uniprot.org/uniprot/A0A386HGL3 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS02585 ^@ http://purl.uniprot.org/uniprot/A0A386HB01 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/1604335:DXZ79_RS11160 ^@ http://purl.uniprot.org/uniprot/A0A386HEI8 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/1604335:DXZ79_RS05555 ^@ http://purl.uniprot.org/uniprot/A0A8D4N4L2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1604335:DXZ79_RS07935 ^@ http://purl.uniprot.org/uniprot/A0A8D4N384 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1604335:DXZ79_RS12050 ^@ http://purl.uniprot.org/uniprot/A0A386HG24 ^@ Function|||Similarity|||Subunit ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.|||Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.|||Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site. http://togogenome.org/gene/1604335:DXZ79_RS17065 ^@ http://purl.uniprot.org/uniprot/A0A386HHU0 ^@ Cofactor ^@ Binds 1 phosphopantetheine covalently. http://togogenome.org/gene/1604335:DXZ79_RS06730 ^@ http://purl.uniprot.org/uniprot/A0A386HCA4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome b560 family.|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/1604335:DXZ79_RS13990 ^@ http://purl.uniprot.org/uniprot/A0A386HH37 ^@ Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.|||Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue. http://togogenome.org/gene/1604335:DXZ79_RS07570 ^@ http://purl.uniprot.org/uniprot/A0A386HCU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0299 family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS13415 ^@ http://purl.uniprot.org/uniprot/A0A386HFI5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.|||Cell inner membrane|||Involved in transporting aromatic amino acids across the cytoplasmic membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS08645 ^@ http://purl.uniprot.org/uniprot/A0A8D4N1K2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgI family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/1604335:DXZ79_RS04700 ^@ http://purl.uniprot.org/uniprot/A0A386HBY5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/1604335:DXZ79_RS03365 ^@ http://purl.uniprot.org/uniprot/A0A386HAY6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphopentomutase family.|||Binds 1 or 2 manganese ions.|||Cytoplasm|||Phosphotransfer between the C1 and C5 carbon atoms of pentose. http://togogenome.org/gene/1604335:DXZ79_RS12765 ^@ http://purl.uniprot.org/uniprot/A0A386HF87 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS04935 ^@ http://purl.uniprot.org/uniprot/A0A8D4MZZ3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS14830 ^@ http://purl.uniprot.org/uniprot/A0A386HHI0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS12605 ^@ http://purl.uniprot.org/uniprot/A0A386HFG3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS02140 ^@ http://purl.uniprot.org/uniprot/A0A386HAS7 ^@ Function|||Similarity ^@ Belongs to the UxaA family.|||Catalyzes the dehydration of galactarate to form 5-dehydro-4-deoxy-D-glucarate (5-KDG). http://togogenome.org/gene/1604335:DXZ79_RS11890 ^@ http://purl.uniprot.org/uniprot/A0A386HEQ1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS02175 ^@ http://purl.uniprot.org/uniprot/A0A386HAI9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.|||Cell inner membrane|||Membrane|||Responsible for the transport of C4-dicarboxylates. http://togogenome.org/gene/1604335:DXZ79_RS13830 ^@ http://purl.uniprot.org/uniprot/A0A386HG64 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/1604335:DXZ79_RS00475 ^@ http://purl.uniprot.org/uniprot/A0A386H9K8 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS02765 ^@ http://purl.uniprot.org/uniprot/A0A386HAV1 ^@ Caution|||Function|||Similarity ^@ Belongs to the ribose 1,5-bisphosphokinase family.|||Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS15840 ^@ http://purl.uniprot.org/uniprot/A0A8D4N3Z8 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/1604335:DXZ79_RS13530 ^@ http://purl.uniprot.org/uniprot/A0A386HGC4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1604335:DXZ79_RS13835 ^@ http://purl.uniprot.org/uniprot/A0A386HH13 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1604335:DXZ79_RS20530 ^@ http://purl.uniprot.org/uniprot/A0A386HJZ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS16370 ^@ http://purl.uniprot.org/uniprot/A0A386HHR4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/1604335:DXZ79_RS17420 ^@ http://purl.uniprot.org/uniprot/A0A386HIA2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/1604335:DXZ79_RS18695 ^@ http://purl.uniprot.org/uniprot/A0A386HIK6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/1604335:DXZ79_RS07805 ^@ http://purl.uniprot.org/uniprot/A0A386HD71 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial microcompartment|||Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/1604335:DXZ79_RS03810 ^@ http://purl.uniprot.org/uniprot/A0A386HAV2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS17230 ^@ http://purl.uniprot.org/uniprot/A0A386HHW6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbD/TolR family.|||Cell inner membrane|||Cell membrane|||Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.|||Membrane|||The accessory proteins ExbB and ExbD seem to form a complex with TonB. http://togogenome.org/gene/1604335:DXZ79_RS04005 ^@ http://purl.uniprot.org/uniprot/A0A386HBL8 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/1604335:DXZ79_RS10825 ^@ http://purl.uniprot.org/uniprot/A0A386HEJ2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M14 family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Involved in muropeptide degradation. Catalyzes the hydrolysis of the gamma-D-glutamyl-diaminopimelic acid (gamma-D-Glu-Dap) amide bond in the murein tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelic acid, leading to the formation of L-Ala-gamma-D-Glu and Dap. http://togogenome.org/gene/1604335:DXZ79_RS10560 ^@ http://purl.uniprot.org/uniprot/A0A386HE31 ^@ Similarity ^@ Belongs to the DDAH family. http://togogenome.org/gene/1604335:DXZ79_RS14915 ^@ http://purl.uniprot.org/uniprot/A0A386HGW1 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/1604335:DXZ79_RS12335 ^@ http://purl.uniprot.org/uniprot/A0A386HF19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS12655 ^@ http://purl.uniprot.org/uniprot/A0A386HFR3 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.|||Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs. http://togogenome.org/gene/1604335:DXZ79_RS04890 ^@ http://purl.uniprot.org/uniprot/A0A386HBW6 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Electron transport system for the ribonucleotide reductase system NrdEF. http://togogenome.org/gene/1604335:DXZ79_RS09865 ^@ http://purl.uniprot.org/uniprot/A0A386HDW9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidine kinase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1604335:DXZ79_RS17810 ^@ http://purl.uniprot.org/uniprot/A0A386HIC6 ^@ PTM|||Subcellular Location Annotation ^@ Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.|||Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS02880 ^@ http://purl.uniprot.org/uniprot/A0A386HB35 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/1604335:DXZ79_RS02835 ^@ http://purl.uniprot.org/uniprot/A0A386HAW5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS12790 ^@ http://purl.uniprot.org/uniprot/A0A386HFP6 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS17270 ^@ http://purl.uniprot.org/uniprot/A0A386HHX3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsP family.|||Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS14575 ^@ http://purl.uniprot.org/uniprot/A0A386HG33 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS19095 ^@ http://purl.uniprot.org/uniprot/A0A386HJ96 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1604335:DXZ79_RS15170 ^@ http://purl.uniprot.org/uniprot/A0A386HGW7 ^@ Similarity ^@ Belongs to the CDP-glycerol glycerophosphotransferase family. http://togogenome.org/gene/1604335:DXZ79_RS12385 ^@ http://purl.uniprot.org/uniprot/A0A386HFN1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.|||Cell membrane|||K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels. http://togogenome.org/gene/1604335:DXZ79_RS07180 ^@ http://purl.uniprot.org/uniprot/A0A386HCT9 ^@ Similarity ^@ Belongs to the phosphate/phosphite/phosphonate binding protein family. http://togogenome.org/gene/1604335:DXZ79_RS12750 ^@ http://purl.uniprot.org/uniprot/A0A386HFJ2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS04130 ^@ http://purl.uniprot.org/uniprot/A0A386HBR4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS17410 ^@ http://purl.uniprot.org/uniprot/A0A386HHH1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/1604335:DXZ79_RS16930 ^@ http://purl.uniprot.org/uniprot/A0A386HI13 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1604335:DXZ79_RS12910 ^@ http://purl.uniprot.org/uniprot/A0A386HFM2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS13510 ^@ http://purl.uniprot.org/uniprot/A0A386HG56 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/1604335:DXZ79_RS13250 ^@ http://purl.uniprot.org/uniprot/A0A386HFW4 ^@ Similarity ^@ Belongs to the UPF0352 family. http://togogenome.org/gene/1604335:DXZ79_RS00130 ^@ http://purl.uniprot.org/uniprot/A0A386H9K6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.|||Belongs to the SrkA/RdoA protein kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS19100 ^@ http://purl.uniprot.org/uniprot/A0A386HIV2 ^@ Similarity ^@ Belongs to the SlyX family. http://togogenome.org/gene/1604335:DXZ79_RS03980 ^@ http://purl.uniprot.org/uniprot/A0A386HAY5 ^@ Cofactor|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Binds 1 [4Fe-4S] cluster per subunit. http://togogenome.org/gene/1604335:DXZ79_RS01355 ^@ http://purl.uniprot.org/uniprot/A0A386HA72 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS04580 ^@ http://purl.uniprot.org/uniprot/A0A386HBG2 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/1604335:DXZ79_RS20495 ^@ http://purl.uniprot.org/uniprot/A0A8E4BMA9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family. http://togogenome.org/gene/1604335:DXZ79_RS07085 ^@ http://purl.uniprot.org/uniprot/A0A386HK50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS15720 ^@ http://purl.uniprot.org/uniprot/A0A386HH65 ^@ Function ^@ Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. http://togogenome.org/gene/1604335:DXZ79_RS05370 ^@ http://purl.uniprot.org/uniprot/A0A8E4BCX5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Cytoplasm|||Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.|||Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. http://togogenome.org/gene/1604335:DXZ79_RS02520 ^@ http://purl.uniprot.org/uniprot/A0A386HA50 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LDH/MDH superfamily. MDH type 1 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS13455 ^@ http://purl.uniprot.org/uniprot/A0A386HG11 ^@ Function|||Similarity|||Subunit ^@ Belongs to the AB hydrolase superfamily. MenH family.|||Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS09100 ^@ http://purl.uniprot.org/uniprot/A0A386HDR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS13335 ^@ http://purl.uniprot.org/uniprot/A0A386HFZ0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Gram-negative porin family.|||Cell outer membrane|||Homotrimer.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS19060 ^@ http://purl.uniprot.org/uniprot/A0A386HJM1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS00200 ^@ http://purl.uniprot.org/uniprot/A0A8D4MWN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0761 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS18420 ^@ http://purl.uniprot.org/uniprot/A0A386HJB6 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS07875 ^@ http://purl.uniprot.org/uniprot/A0A386HDD5 ^@ Similarity ^@ Belongs to the diol/glycerol dehydratase large subunit family. http://togogenome.org/gene/1604335:DXZ79_RS05225 ^@ http://purl.uniprot.org/uniprot/A0A386HBI4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/1604335:DXZ79_RS13600 ^@ http://purl.uniprot.org/uniprot/A0A386HFQ2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS16685 ^@ http://purl.uniprot.org/uniprot/A0A386HH50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS03370 ^@ http://purl.uniprot.org/uniprot/A0A386HB24 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.|||Homohexamer; trimer of homodimers. http://togogenome.org/gene/1604335:DXZ79_RS11440 ^@ http://purl.uniprot.org/uniprot/A0A386HF69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS13025 ^@ http://purl.uniprot.org/uniprot/A0A386HGM7 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1604335:DXZ79_RS10980 ^@ http://purl.uniprot.org/uniprot/A0A8E4DEG0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS00330 ^@ http://purl.uniprot.org/uniprot/A0A386H9Z8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/1604335:DXZ79_RS14760 ^@ http://purl.uniprot.org/uniprot/A0A386HH42 ^@ Function|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily. Cof family.|||Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P). http://togogenome.org/gene/1604335:DXZ79_RS15685 ^@ http://purl.uniprot.org/uniprot/A0A386HGN6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.|||Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS18925 ^@ http://purl.uniprot.org/uniprot/A0A386HI53 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/1604335:DXZ79_RS10800 ^@ http://purl.uniprot.org/uniprot/A0A386HEY3 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TtcA family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.|||Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.|||Cytoplasm|||Homodimer.|||The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster. http://togogenome.org/gene/1604335:DXZ79_RS11155 ^@ http://purl.uniprot.org/uniprot/A0A386HF91 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/1604335:DXZ79_RS18410 ^@ http://purl.uniprot.org/uniprot/A0A386HIA3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/1604335:DXZ79_RS06375 ^@ http://purl.uniprot.org/uniprot/A0A386HCW1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TatA/E family. TatE subfamily.|||Cell inner membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA. http://togogenome.org/gene/1604335:DXZ79_RS19035 ^@ http://purl.uniprot.org/uniprot/A0A386HJ43 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1604335:DXZ79_RS06090 ^@ http://purl.uniprot.org/uniprot/A0A386HCB0 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/1604335:DXZ79_RS08570 ^@ http://purl.uniprot.org/uniprot/A0A386HDR2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CheZ family.|||Cytoplasm|||Homodimer.|||Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). http://togogenome.org/gene/1604335:DXZ79_RS02305 ^@ http://purl.uniprot.org/uniprot/A0A8D4MZ63 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family. http://togogenome.org/gene/1604335:DXZ79_RS19895 ^@ http://purl.uniprot.org/uniprot/A0A386HIM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS04270 ^@ http://purl.uniprot.org/uniprot/A0A386HB39 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PAPS reductase family. CysD subfamily.|||Heterodimer composed of CysD, the smaller subunit, and CysN.|||With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD. http://togogenome.org/gene/1604335:DXZ79_RS00245 ^@ http://purl.uniprot.org/uniprot/A0A386H9M5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.|||Catalyzes the sodium-dependent transport of glutamate.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS17570 ^@ http://purl.uniprot.org/uniprot/A0A386HHJ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS08335 ^@ http://purl.uniprot.org/uniprot/A0A386HDL6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the P-Pant transferase superfamily. EntD family.|||EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.|||Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively. http://togogenome.org/gene/1604335:DXZ79_RS00985 ^@ http://purl.uniprot.org/uniprot/A0A386H9Z2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS03315 ^@ http://purl.uniprot.org/uniprot/A0A386HAJ3 ^@ Function ^@ DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. http://togogenome.org/gene/1604335:DXZ79_RS08725 ^@ http://purl.uniprot.org/uniprot/A0A8D4N133 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively. http://togogenome.org/gene/1604335:DXZ79_RS03350 ^@ http://purl.uniprot.org/uniprot/A0A386HB41 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS06625 ^@ http://purl.uniprot.org/uniprot/A0A8E4BME9 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1604335:DXZ79_RS20340 ^@ http://purl.uniprot.org/uniprot/A0A386HJC8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/1604335:DXZ79_RS17555 ^@ http://purl.uniprot.org/uniprot/A0A386HI31 ^@ Function|||Induction|||Miscellaneous|||Similarity|||Subunit ^@ A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.|||Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.|||Homodimer.|||Induced by MurNAc 6-phosphate that releases the repressor MurR from the DNA. Repressed by MurR in the absence of MurNAc 6-phosphate.|||Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. http://togogenome.org/gene/1604335:DXZ79_RS04465 ^@ http://purl.uniprot.org/uniprot/A0A386HBN9 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1604335:DXZ79_RS12270 ^@ http://purl.uniprot.org/uniprot/A0A386HFA4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase E/G family. RNase E subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per homotetramer.|||Cell inner membrane|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.|||Cytoplasm|||Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. http://togogenome.org/gene/1604335:DXZ79_RS03500 ^@ http://purl.uniprot.org/uniprot/A0A8D4MZ19 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS15215 ^@ http://purl.uniprot.org/uniprot/A0A386HGV8 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/1604335:DXZ79_RS05420 ^@ http://purl.uniprot.org/uniprot/A0A8D4MY78 ^@ Function|||Similarity ^@ Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.|||Protects the bacterial cell from host peptidases. http://togogenome.org/gene/1604335:DXZ79_RS03710 ^@ http://purl.uniprot.org/uniprot/A0A386HAT2 ^@ Similarity|||Subunit ^@ Belongs to the beta-eliminating lyase family.|||Homotetramer. http://togogenome.org/gene/1604335:DXZ79_RS11720 ^@ http://purl.uniprot.org/uniprot/A0A386HEZ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CopC family.|||Involved in copper resistance. Appears to be involved in copper uptake.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS03110 ^@ http://purl.uniprot.org/uniprot/A0A8D4SR67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS06210 ^@ http://purl.uniprot.org/uniprot/A0A386HC02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS18965 ^@ http://purl.uniprot.org/uniprot/A0A386HIY5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1604335:DXZ79_RS18980 ^@ http://purl.uniprot.org/uniprot/A0A386HIW7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1604335:DXZ79_RS05880 ^@ http://purl.uniprot.org/uniprot/A0A386HCN0 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/1604335:DXZ79_RS02485 ^@ http://purl.uniprot.org/uniprot/A0A386HAP7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/1604335:DXZ79_RS16945 ^@ http://purl.uniprot.org/uniprot/A0A386HHR9 ^@ Function|||Similarity ^@ Belongs to the FlgD family.|||Required for flagellar hook formation. May act as a scaffolding protein. http://togogenome.org/gene/1604335:DXZ79_RS12115 ^@ http://purl.uniprot.org/uniprot/A0A386HFJ0 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/1604335:DXZ79_RS06760 ^@ http://purl.uniprot.org/uniprot/A0A386HCP7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/1604335:DXZ79_RS03705 ^@ http://purl.uniprot.org/uniprot/A0A386HAS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Set transporter family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS20360 ^@ http://purl.uniprot.org/uniprot/A0A386HIV5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/1604335:DXZ79_RS02410 ^@ http://purl.uniprot.org/uniprot/A0A386HA31 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/1604335:DXZ79_RS17800 ^@ http://purl.uniprot.org/uniprot/A0A386HHM8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 51 family.|||Cell inner membrane|||Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. http://togogenome.org/gene/1604335:DXZ79_RS10225 ^@ http://purl.uniprot.org/uniprot/A0A386HDY7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/1604335:DXZ79_RS18665 ^@ http://purl.uniprot.org/uniprot/A0A386HIR9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the Nudix hydrolase family. NudC subfamily.|||Binds 1 zinc ion per subunit.|||Divalent metal cations. Mg(2+) or Mn(2+).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates. http://togogenome.org/gene/1604335:DXZ79_RS04430 ^@ http://purl.uniprot.org/uniprot/A0A386HBH8 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1604335:DXZ79_RS13450 ^@ http://purl.uniprot.org/uniprot/A0A386HGU1 ^@ Caution|||Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.|||Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS16425 ^@ http://purl.uniprot.org/uniprot/A0A386HH10 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-I family. http://togogenome.org/gene/1604335:DXZ79_RS11815 ^@ http://purl.uniprot.org/uniprot/A0A386HF85 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS11210 ^@ http://purl.uniprot.org/uniprot/A0A8D4SS34 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/1604335:DXZ79_RS17900 ^@ http://purl.uniprot.org/uniprot/A0A386HI87 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD). http://togogenome.org/gene/1604335:DXZ79_RS19370 ^@ http://purl.uniprot.org/uniprot/A0A386HJ50 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS16975 ^@ http://purl.uniprot.org/uniprot/A0A386HHY1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS19270 ^@ http://purl.uniprot.org/uniprot/A0A386HJ82 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS08765 ^@ http://purl.uniprot.org/uniprot/A0A386HDT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/1604335:DXZ79_RS14170 ^@ http://purl.uniprot.org/uniprot/A0A386HH68 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS17415 ^@ http://purl.uniprot.org/uniprot/A0A386HI56 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/1604335:DXZ79_RS07680 ^@ http://purl.uniprot.org/uniprot/A0A386HCV4 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS03135 ^@ http://purl.uniprot.org/uniprot/A0A8D4MYY9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LsrG family.|||Cytoplasm|||Homodimer.|||Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5-phosphonooxypentane-2,4-dione (P-HPD). http://togogenome.org/gene/1604335:DXZ79_RS06075 ^@ http://purl.uniprot.org/uniprot/A0A386HC55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS05180 ^@ http://purl.uniprot.org/uniprot/A0A386HC73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RseB family.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS14950 ^@ http://purl.uniprot.org/uniprot/A0A8D4N649 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1604335:DXZ79_RS07670 ^@ http://purl.uniprot.org/uniprot/A0A386HD83 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/1604335:DXZ79_RS05205 ^@ http://purl.uniprot.org/uniprot/A0A8D4SR33 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS00215 ^@ http://purl.uniprot.org/uniprot/A0A386HIZ5 ^@ Similarity ^@ Belongs to the ner transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS06240 ^@ http://purl.uniprot.org/uniprot/A0A386HJQ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS04885 ^@ http://purl.uniprot.org/uniprot/A0A386HC23 ^@ Function|||Similarity ^@ Belongs to the NrdI family.|||Probably involved in ribonucleotide reductase function. http://togogenome.org/gene/1604335:DXZ79_RS16105 ^@ http://purl.uniprot.org/uniprot/A0A386HHS1 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/1604335:DXZ79_RS11550 ^@ http://purl.uniprot.org/uniprot/A0A386HEW5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS04165 ^@ http://purl.uniprot.org/uniprot/A0A386HBI5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS09755 ^@ http://purl.uniprot.org/uniprot/A0A386HE05 ^@ Cofactor|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein. http://togogenome.org/gene/1604335:DXZ79_RS12220 ^@ http://purl.uniprot.org/uniprot/A0A386HFK7 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS14500 ^@ http://purl.uniprot.org/uniprot/A0A386HHC6 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/1604335:DXZ79_RS14810 ^@ http://purl.uniprot.org/uniprot/A0A386HH52 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/1604335:DXZ79_RS10555 ^@ http://purl.uniprot.org/uniprot/A0A8E3ZHT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS02240 ^@ http://purl.uniprot.org/uniprot/A0A386HA22 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FrdC family.|||Cell membrane|||Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).|||Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones. http://togogenome.org/gene/1604335:DXZ79_RS00910 ^@ http://purl.uniprot.org/uniprot/A0A386HA23 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1604335:DXZ79_RS08425 ^@ http://purl.uniprot.org/uniprot/A0A386HDM3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/1604335:DXZ79_RS20220 ^@ http://purl.uniprot.org/uniprot/A0A386HJD6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1604335:DXZ79_RS12055 ^@ http://purl.uniprot.org/uniprot/A0A386HF63 ^@ Subcellular Location Annotation ^@ Cell outer membrane http://togogenome.org/gene/1604335:DXZ79_RS08840 ^@ http://purl.uniprot.org/uniprot/A0A8D4N411 ^@ Function|||Similarity ^@ Belongs to the EfeM/EfeO family.|||Involved in Fe(2+) uptake. Could be an iron-binding and/or electron-transfer component. http://togogenome.org/gene/1604335:DXZ79_RS01650 ^@ http://purl.uniprot.org/uniprot/A0A386HA90 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS13555 ^@ http://purl.uniprot.org/uniprot/A0A386HG30 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1604335:DXZ79_RS02620 ^@ http://purl.uniprot.org/uniprot/A0A386HB37 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/1604335:DXZ79_RS01675 ^@ http://purl.uniprot.org/uniprot/A0A386HAF1 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/1604335:DXZ79_RS03355 ^@ http://purl.uniprot.org/uniprot/A0A386HBD8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS15205 ^@ http://purl.uniprot.org/uniprot/A0A386HHC4 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/1604335:DXZ79_RS04245 ^@ http://purl.uniprot.org/uniprot/A0A386HBA0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.|||Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family.|||Binds 1 FAD per subunit.|||Binds 1 FMN per subunit.|||Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.|||In the N-terminal section; belongs to the flavodoxin family. http://togogenome.org/gene/1604335:DXZ79_RS08925 ^@ http://purl.uniprot.org/uniprot/A0A8D4N5P6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gtrA family.|||Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS18865 ^@ http://purl.uniprot.org/uniprot/A0A386HKE9 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/1604335:DXZ79_RS19600 ^@ http://purl.uniprot.org/uniprot/A0A386HJ75 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Gfo/Idh/MocA family.|||Homotetramer.|||Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose). http://togogenome.org/gene/1604335:DXZ79_RS14985 ^@ http://purl.uniprot.org/uniprot/A0A386HKX1 ^@ Function|||Similarity ^@ Belongs to the AcpH family.|||Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP. http://togogenome.org/gene/1604335:DXZ79_RS15025 ^@ http://purl.uniprot.org/uniprot/A0A386HGB4 ^@ Function ^@ Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals. http://togogenome.org/gene/1604335:DXZ79_RS13540 ^@ http://purl.uniprot.org/uniprot/A0A386HFP2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS01070 ^@ http://purl.uniprot.org/uniprot/A0A8D4SQE7 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1604335:DXZ79_RS04685 ^@ http://purl.uniprot.org/uniprot/A0A8D4N4B8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/1604335:DXZ79_RS18520 ^@ http://purl.uniprot.org/uniprot/A0A8D4SRS9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.|||Cell inner membrane|||Cell membrane|||Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (MalK), two transmembrane proteins (MalG and MalF) and a solute-binding protein (MalE). http://togogenome.org/gene/1604335:DXZ79_RS10200 ^@ http://purl.uniprot.org/uniprot/A0A386HEG5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNR ribonuclease family. RNase II subfamily.|||Cytoplasm|||Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction. http://togogenome.org/gene/1604335:DXZ79_RS09375 ^@ http://purl.uniprot.org/uniprot/A0A386HE58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS10410 ^@ http://purl.uniprot.org/uniprot/A0A386HE60 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1604335:DXZ79_RS16995 ^@ http://purl.uniprot.org/uniprot/A0A386HHS8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively. http://togogenome.org/gene/1604335:DXZ79_RS00335 ^@ http://purl.uniprot.org/uniprot/A0A386H9Q4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS15255 ^@ http://purl.uniprot.org/uniprot/A0A386HHD4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS08480 ^@ http://purl.uniprot.org/uniprot/A0A386HDR7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS20140 ^@ http://purl.uniprot.org/uniprot/A0A386HIQ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SelA family.|||Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.|||Cytoplasm|||Homodecamer; pentamer of dimers. Binds only one seryl-tRNA(Sec) per dimer. http://togogenome.org/gene/1604335:DXZ79_RS15670 ^@ http://purl.uniprot.org/uniprot/A0A386HH56 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS06185 ^@ http://purl.uniprot.org/uniprot/A0A386HCF2 ^@ Function ^@ Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. http://togogenome.org/gene/1604335:DXZ79_RS11185 ^@ http://purl.uniprot.org/uniprot/A0A386HF35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS05865 ^@ http://purl.uniprot.org/uniprot/A0A386HCQ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Nudix hydrolase family. NudK subfamily.|||Homodimer.|||Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate. http://togogenome.org/gene/1604335:DXZ79_RS03550 ^@ http://purl.uniprot.org/uniprot/A0A386HAP9 ^@ Function|||Similarity ^@ Belongs to the ribF family.|||Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. http://togogenome.org/gene/1604335:DXZ79_RS10235 ^@ http://purl.uniprot.org/uniprot/A0A386HEK6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RnfG family.|||Cell inner membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1604335:DXZ79_RS00270 ^@ http://purl.uniprot.org/uniprot/A0A386H9S3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/1604335:DXZ79_RS02630 ^@ http://purl.uniprot.org/uniprot/A0A386HAQ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/1604335:DXZ79_RS12185 ^@ http://purl.uniprot.org/uniprot/A0A386HFK0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS10435 ^@ http://purl.uniprot.org/uniprot/A0A386HE18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0060 family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS18990 ^@ http://purl.uniprot.org/uniprot/A0A386HJ72 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1604335:DXZ79_RS07105 ^@ http://purl.uniprot.org/uniprot/A0A386HCY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0194 family.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS19000 ^@ http://purl.uniprot.org/uniprot/A0A386HIP7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1604335:DXZ79_RS04085 ^@ http://purl.uniprot.org/uniprot/A0A386HBF8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DksA family.|||Cytoplasm|||Interacts directly with the RNA polymerase.|||Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. http://togogenome.org/gene/1604335:DXZ79_RS03820 ^@ http://purl.uniprot.org/uniprot/A0A386HBK0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. FtsW subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell division. http://togogenome.org/gene/1604335:DXZ79_RS06960 ^@ http://purl.uniprot.org/uniprot/A0A386HD48 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. GalK subfamily.|||Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS01660 ^@ http://purl.uniprot.org/uniprot/A0A386H9T3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS09680 ^@ http://purl.uniprot.org/uniprot/A0A386HEF7 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homodimer.|||Multifunctional regulator of fatty acid metabolism. http://togogenome.org/gene/1604335:DXZ79_RS05130 ^@ http://purl.uniprot.org/uniprot/A0A386HCC5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/1604335:DXZ79_RS09465 ^@ http://purl.uniprot.org/uniprot/A0A386HEB8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CutC family.|||Cytoplasm|||Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case. http://togogenome.org/gene/1604335:DXZ79_RS11950 ^@ http://purl.uniprot.org/uniprot/A0A386HER1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HdeB family.|||Periplasm|||Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins. http://togogenome.org/gene/1604335:DXZ79_RS07595 ^@ http://purl.uniprot.org/uniprot/A0A386HCP0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. http://togogenome.org/gene/1604335:DXZ79_RS07655 ^@ http://purl.uniprot.org/uniprot/A0A386HCQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the PRA-PH family.|||In the N-terminal section; belongs to the PRA-CH family. http://togogenome.org/gene/1604335:DXZ79_RS11240 ^@ http://purl.uniprot.org/uniprot/A0A386HES0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LplA family.|||Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.|||Cytoplasm|||In the transfer reaction, the free carboxyl group of lipoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS13630 ^@ http://purl.uniprot.org/uniprot/A0A386HG76 ^@ Similarity ^@ Belongs to the UPF0304 family. http://togogenome.org/gene/1604335:DXZ79_RS10565 ^@ http://purl.uniprot.org/uniprot/A0A386HE94 ^@ Function|||Similarity ^@ Belongs to the AMP nucleosidase family.|||Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. http://togogenome.org/gene/1604335:DXZ79_RS08865 ^@ http://purl.uniprot.org/uniprot/A0A386HDV6 ^@ Similarity ^@ Belongs to the ner transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS06805 ^@ http://purl.uniprot.org/uniprot/A0A386HCH4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbD/TolR family.|||Cell inner membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/1604335:DXZ79_RS08715 ^@ http://purl.uniprot.org/uniprot/A0A386HE00 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliH family.|||Cytoplasm|||Needed for flagellar regrowth and assembly. http://togogenome.org/gene/1604335:DXZ79_RS03840 ^@ http://purl.uniprot.org/uniprot/A0A386HB15 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsQ/DivIB family. FtsQ subfamily.|||Cell inner membrane|||Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.|||Part of a complex composed of FtsB, FtsL and FtsQ. http://togogenome.org/gene/1604335:DXZ79_RS07830 ^@ http://purl.uniprot.org/uniprot/A0A386HCT2 ^@ Similarity ^@ Belongs to the CcmL/EutN family. http://togogenome.org/gene/1604335:DXZ79_RS06040 ^@ http://purl.uniprot.org/uniprot/A0A386HCT5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS07675 ^@ http://purl.uniprot.org/uniprot/A0A386HDJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.|||In the N-terminal section; belongs to the histidinol-phosphatase family. http://togogenome.org/gene/1604335:DXZ79_RS14030 ^@ http://purl.uniprot.org/uniprot/A0A386HGS2 ^@ Similarity ^@ Belongs to the MlaA family. http://togogenome.org/gene/1604335:DXZ79_RS07955 ^@ http://purl.uniprot.org/uniprot/A0A386HDP4 ^@ Function|||Similarity ^@ Belongs to the CbiK family.|||Catalyzes the insertion of Co(2+) into sirohydrochlorin. http://togogenome.org/gene/1604335:DXZ79_RS01120 ^@ http://purl.uniprot.org/uniprot/A0A386HAC0 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/1604335:DXZ79_RS07555 ^@ http://purl.uniprot.org/uniprot/A0A386HDB0 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese.|||Homotetramer. http://togogenome.org/gene/1604335:DXZ79_RS14705 ^@ http://purl.uniprot.org/uniprot/A0A386HGM2 ^@ Similarity ^@ Belongs to the Hha/YmoA/Cnu family. http://togogenome.org/gene/1604335:DXZ79_RS07375 ^@ http://purl.uniprot.org/uniprot/A0A386HD27 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1604335:DXZ79_RS05000 ^@ http://purl.uniprot.org/uniprot/A0A386HBY7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UreE family.|||Cytoplasm|||Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. http://togogenome.org/gene/1604335:DXZ79_RS12815 ^@ http://purl.uniprot.org/uniprot/A0A386HF97 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/1604335:DXZ79_RS12095 ^@ http://purl.uniprot.org/uniprot/A0A8D4N3T5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.|||Cell inner membrane|||Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.|||The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE). http://togogenome.org/gene/1604335:DXZ79_RS04905 ^@ http://purl.uniprot.org/uniprot/A0A386HBV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ElaB/YgaM/YqjD family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS05725 ^@ http://purl.uniprot.org/uniprot/A0A386HCA2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS07780 ^@ http://purl.uniprot.org/uniprot/A0A386HCR9 ^@ Function ^@ Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin. http://togogenome.org/gene/1604335:DXZ79_RS12700 ^@ http://purl.uniprot.org/uniprot/A0A8D4SQU6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS17600 ^@ http://purl.uniprot.org/uniprot/A0A386HIW9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RlmG family.|||Cytoplasm|||Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. http://togogenome.org/gene/1604335:DXZ79_RS02460 ^@ http://purl.uniprot.org/uniprot/A0A386HA40 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS11265 ^@ http://purl.uniprot.org/uniprot/A0A8D4SQL7 ^@ Function|||Similarity ^@ Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.|||Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. http://togogenome.org/gene/1604335:DXZ79_RS18915 ^@ http://purl.uniprot.org/uniprot/A0A386HIX2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/1604335:DXZ79_RS10530 ^@ http://purl.uniprot.org/uniprot/A0A386HE77 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase family. http://togogenome.org/gene/1604335:DXZ79_RS08935 ^@ http://purl.uniprot.org/uniprot/A0A386HDY6 ^@ Similarity ^@ Belongs to the DinB family. http://togogenome.org/gene/1604335:DXZ79_RS16250 ^@ http://purl.uniprot.org/uniprot/A0A386HGY3 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS07000 ^@ http://purl.uniprot.org/uniprot/A0A8D4N2X6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1604335:DXZ79_RS00705 ^@ http://purl.uniprot.org/uniprot/A0A386H9P7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS02325 ^@ http://purl.uniprot.org/uniprot/A0A386HAS4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS03480 ^@ http://purl.uniprot.org/uniprot/A0A386HB44 ^@ Similarity ^@ Belongs to the UPF0246 family. http://togogenome.org/gene/1604335:DXZ79_RS07990 ^@ http://purl.uniprot.org/uniprot/A0A386HDF6 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/1604335:DXZ79_RS04320 ^@ http://purl.uniprot.org/uniprot/A0A386HBJ9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). http://togogenome.org/gene/1604335:DXZ79_RS14200 ^@ http://purl.uniprot.org/uniprot/A0A386HGI6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS11295 ^@ http://purl.uniprot.org/uniprot/A0A386HJW8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF). http://togogenome.org/gene/1604335:DXZ79_RS14805 ^@ http://purl.uniprot.org/uniprot/A0A386HGZ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1604335:DXZ79_RS08340 ^@ http://purl.uniprot.org/uniprot/A0A386HD30 ^@ Subcellular Location Annotation ^@ Cell outer membrane http://togogenome.org/gene/1604335:DXZ79_RS07885 ^@ http://purl.uniprot.org/uniprot/A0A386HCU0 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial microcompartment|||Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/1604335:DXZ79_RS19115 ^@ http://purl.uniprot.org/uniprot/A0A386HJM8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.|||Cell inner membrane|||Interacts with the regulatory subunit KefG.|||Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. http://togogenome.org/gene/1604335:DXZ79_RS08670 ^@ http://purl.uniprot.org/uniprot/A0A386HE45 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1604335:DXZ79_RS07315 ^@ http://purl.uniprot.org/uniprot/A0A386HCV8 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1604335:DXZ79_RS13725 ^@ http://purl.uniprot.org/uniprot/A0A386HGZ3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DedD family.|||Cell inner membrane|||Non-essential cell division protein that could be required for efficient cell constriction.|||The SPOR domain binds septal peptidoglycans and is required to target DedD to the septal ring. http://togogenome.org/gene/1604335:DXZ79_RS18720 ^@ http://purl.uniprot.org/uniprot/A0A386HIY2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1604335:DXZ79_RS11060 ^@ http://purl.uniprot.org/uniprot/A0A8D4N4V4 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1604335:DXZ79_RS18710 ^@ http://purl.uniprot.org/uniprot/A0A386HI18 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1604335:DXZ79_RS07985 ^@ http://purl.uniprot.org/uniprot/A0A8E4BME3 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. http://togogenome.org/gene/1604335:DXZ79_RS12230 ^@ http://purl.uniprot.org/uniprot/A0A8D4N269 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/1604335:DXZ79_RS16415 ^@ http://purl.uniprot.org/uniprot/A0A8D4SRS7 ^@ Function|||Similarity ^@ Belongs to the transglycosylase Slt family.|||Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. http://togogenome.org/gene/1604335:DXZ79_RS15555 ^@ http://purl.uniprot.org/uniprot/A0A386HGM3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/1604335:DXZ79_RS14935 ^@ http://purl.uniprot.org/uniprot/A0A386HGR4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/1604335:DXZ79_RS10420 ^@ http://purl.uniprot.org/uniprot/A0A8D4SRZ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response. http://togogenome.org/gene/1604335:DXZ79_RS05490 ^@ http://purl.uniprot.org/uniprot/A0A8D4N366 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1604335:DXZ79_RS09130 ^@ http://purl.uniprot.org/uniprot/A0A8D4N5S0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS19515 ^@ http://purl.uniprot.org/uniprot/A0A386HIY7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS06945 ^@ http://purl.uniprot.org/uniprot/A0A386HD75 ^@ Function|||Similarity|||Subunit ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS02655 ^@ http://purl.uniprot.org/uniprot/A0A386HAY9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cell membrane|||Homodimer.|||May be involved in cell division. http://togogenome.org/gene/1604335:DXZ79_RS02405 ^@ http://purl.uniprot.org/uniprot/A0A386HAM8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PriB family.|||Binds single-stranded DNA at the primosome assembly site (PAS).|||Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome. http://togogenome.org/gene/1604335:DXZ79_RS15295 ^@ http://purl.uniprot.org/uniprot/A0A386HH35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrB/RnfD family.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/1604335:DXZ79_RS20540 ^@ http://purl.uniprot.org/uniprot/A0A386HJG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS14600 ^@ http://purl.uniprot.org/uniprot/A0A386HGK1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS03440 ^@ http://purl.uniprot.org/uniprot/A0A386HB53 ^@ Caution|||Similarity ^@ Belongs to the phosphoglycerate mutase family. GpmB subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS19065 ^@ http://purl.uniprot.org/uniprot/A0A386HIR0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1604335:DXZ79_RS13860 ^@ http://purl.uniprot.org/uniprot/A0A8D4N237 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1604335:DXZ79_RS20380 ^@ http://purl.uniprot.org/uniprot/A0A386HJG8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits. http://togogenome.org/gene/1604335:DXZ79_RS13110 ^@ http://purl.uniprot.org/uniprot/A0A386HG07 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS00190 ^@ http://purl.uniprot.org/uniprot/A0A386H9L5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS00815 ^@ http://purl.uniprot.org/uniprot/A0A8D4N0B5 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1604335:DXZ79_RS05495 ^@ http://purl.uniprot.org/uniprot/A0A386HBS2 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/1604335:DXZ79_RS03680 ^@ http://purl.uniprot.org/uniprot/A0A386HBA2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane|||Membrane|||The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB). http://togogenome.org/gene/1604335:DXZ79_RS14570 ^@ http://purl.uniprot.org/uniprot/A0A8D4N5G5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS07920 ^@ http://purl.uniprot.org/uniprot/A0A386HDQ5 ^@ Function|||Similarity ^@ Belongs to the CbiD family.|||Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. http://togogenome.org/gene/1604335:DXZ79_RS09340 ^@ http://purl.uniprot.org/uniprot/A0A386HE44 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS06725 ^@ http://purl.uniprot.org/uniprot/A0A386HCR4 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1604335:DXZ79_RS11310 ^@ http://purl.uniprot.org/uniprot/A0A386HEK8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/1604335:DXZ79_RS12760 ^@ http://purl.uniprot.org/uniprot/A0A386HF60 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.|||Cell inner membrane|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS19905 ^@ http://purl.uniprot.org/uniprot/A0A386HJC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 5 family.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS08250 ^@ http://purl.uniprot.org/uniprot/A0A386HDJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS00620 ^@ http://purl.uniprot.org/uniprot/A0A386H9Y4 ^@ Similarity|||Subunit ^@ Homotetramer.|||In the C-terminal section; belongs to the homoserine dehydrogenase family.|||In the N-terminal section; belongs to the aspartokinase family. http://togogenome.org/gene/1604335:DXZ79_RS09530 ^@ http://purl.uniprot.org/uniprot/A0A386HEL7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS19455 ^@ http://purl.uniprot.org/uniprot/A0A386HJ08 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/1604335:DXZ79_RS05145 ^@ http://purl.uniprot.org/uniprot/A0A386HC82 ^@ Function ^@ Acts as a radical domain for damaged PFL and possibly other radical proteins. http://togogenome.org/gene/1604335:DXZ79_RS14160 ^@ http://purl.uniprot.org/uniprot/A0A386HFW9 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/1604335:DXZ79_RS05780 ^@ http://purl.uniprot.org/uniprot/A0A386HC66 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/1604335:DXZ79_RS17790 ^@ http://purl.uniprot.org/uniprot/A0A386HK43 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SIS family. DiaA subfamily.|||Homotetramer; dimer of dimers.|||Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. http://togogenome.org/gene/1604335:DXZ79_RS03050 ^@ http://purl.uniprot.org/uniprot/A0A8D4MXI8 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1604335:DXZ79_RS02415 ^@ http://purl.uniprot.org/uniprot/A0A386HA49 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/1604335:DXZ79_RS04095 ^@ http://purl.uniprot.org/uniprot/A0A386HAZ9 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/1604335:DXZ79_RS01435 ^@ http://purl.uniprot.org/uniprot/A0A386H9V8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. Thiolase family.|||Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.|||Cytoplasm|||Heterotetramer of two alpha chains (FadB) and two beta chains (FadA). http://togogenome.org/gene/1604335:DXZ79_RS09830 ^@ http://purl.uniprot.org/uniprot/A0A386HDS3 ^@ Similarity ^@ Belongs to the UPF0225 family. http://togogenome.org/gene/1604335:DXZ79_RS08855 ^@ http://purl.uniprot.org/uniprot/A0A386HDA7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS11130 ^@ http://purl.uniprot.org/uniprot/A0A386HF24 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.|||Belongs to the Lpp family.|||Cell outer membrane|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||cell wall http://togogenome.org/gene/1604335:DXZ79_RS01505 ^@ http://purl.uniprot.org/uniprot/A0A386HAC1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.|||Catalyzes the proton-dependent transport of glutamate and aspartate.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS20370 ^@ http://purl.uniprot.org/uniprot/A0A386HJR7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/1604335:DXZ79_RS01425 ^@ http://purl.uniprot.org/uniprot/A0A8E4BMF5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UbiD family.|||Binds 1 prenylated FMN (prenyl-FMN) per subunit.|||Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.|||Cell membrane|||Homohexamer. http://togogenome.org/gene/1604335:DXZ79_RS13485 ^@ http://purl.uniprot.org/uniprot/A0A386HGH3 ^@ Similarity ^@ Belongs to the UPF0303 family. http://togogenome.org/gene/1604335:DXZ79_RS12825 ^@ http://purl.uniprot.org/uniprot/A0A8D4N5A6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS15790 ^@ http://purl.uniprot.org/uniprot/A0A8D4N6E4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS15300 ^@ http://purl.uniprot.org/uniprot/A0A386HH80 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NqrA family.|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/1604335:DXZ79_RS15995 ^@ http://purl.uniprot.org/uniprot/A0A8D4SSV9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/1604335:DXZ79_RS04960 ^@ http://purl.uniprot.org/uniprot/A0A386HBM3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS15610 ^@ http://purl.uniprot.org/uniprot/A0A386HH31 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1604335:DXZ79_RS11970 ^@ http://purl.uniprot.org/uniprot/A0A386HFF7 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1604335:DXZ79_RS07645 ^@ http://purl.uniprot.org/uniprot/A0A386HD13 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/1604335:DXZ79_RS17630 ^@ http://purl.uniprot.org/uniprot/A0A8D4ST49 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Cell membrane|||Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS00965 ^@ http://purl.uniprot.org/uniprot/A0A386H9M3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.|||Cell inner membrane|||Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA).|||Membrane|||Probably part of a complex composed of WzxE, WzyE and WzzE. http://togogenome.org/gene/1604335:DXZ79_RS16400 ^@ http://purl.uniprot.org/uniprot/A0A386HIB5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS01310 ^@ http://purl.uniprot.org/uniprot/A0A8D4N140 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS19750 ^@ http://purl.uniprot.org/uniprot/A0A386HJ26 ^@ Function|||Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family.|||Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. http://togogenome.org/gene/1604335:DXZ79_RS13490 ^@ http://purl.uniprot.org/uniprot/A0A386HFN3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS15615 ^@ http://purl.uniprot.org/uniprot/A0A386HHW9 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS13615 ^@ http://purl.uniprot.org/uniprot/A0A8E4FZW6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS13460 ^@ http://purl.uniprot.org/uniprot/A0A386HG47 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the TPP enzyme family. MenD subfamily.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS01665 ^@ http://purl.uniprot.org/uniprot/A0A386HAL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS01500 ^@ http://purl.uniprot.org/uniprot/A0A8D4SP07 ^@ Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.|||Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis. http://togogenome.org/gene/1604335:DXZ79_RS00080 ^@ http://purl.uniprot.org/uniprot/A0A386H9P5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS18000 ^@ http://purl.uniprot.org/uniprot/A0A386HI97 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.|||Cell inner membrane|||Mediates magnesium influx to the cytosol. http://togogenome.org/gene/1604335:DXZ79_RS05025 ^@ http://purl.uniprot.org/uniprot/A0A386HBS6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.|||Cell membrane|||Efflux system for nickel and cobalt.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS03955 ^@ http://purl.uniprot.org/uniprot/A0A386HBF4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 2 lipoyl cofactors covalently.|||Forms a 24-polypeptide structural core with octahedral symmetry.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/1604335:DXZ79_RS12950 ^@ http://purl.uniprot.org/uniprot/A0A386HFE0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/1604335:DXZ79_RS05085 ^@ http://purl.uniprot.org/uniprot/A0A386HBZ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YdjC deacetylase family. ChbG subfamily.|||Cytoplasm|||Homodimer.|||Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF. http://togogenome.org/gene/1604335:DXZ79_RS00725 ^@ http://purl.uniprot.org/uniprot/A0A386HA63 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.|||Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). http://togogenome.org/gene/1604335:DXZ79_RS03805 ^@ http://purl.uniprot.org/uniprot/A0A8D4N012 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/1604335:DXZ79_RS08625 ^@ http://purl.uniprot.org/uniprot/A0A386HD77 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1604335:DXZ79_RS00855 ^@ http://purl.uniprot.org/uniprot/A0A386HA87 ^@ Similarity ^@ Belongs to the phage antitermination Q type 1 family. http://togogenome.org/gene/1604335:DXZ79_RS06745 ^@ http://purl.uniprot.org/uniprot/A0A386HCT4 ^@ Cofactor|||Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/1604335:DXZ79_RS04570 ^@ http://purl.uniprot.org/uniprot/A0A386HBW7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Catalyzes the reversible hydration of fumarate to (S)-malate.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS07975 ^@ http://purl.uniprot.org/uniprot/A0A386HDS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CbiQ family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS16800 ^@ http://purl.uniprot.org/uniprot/A0A386HHN9 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/1604335:DXZ79_RS15325 ^@ http://purl.uniprot.org/uniprot/A0A386HH02 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1604335:DXZ79_RS08400 ^@ http://purl.uniprot.org/uniprot/A0A386HD40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS18430 ^@ http://purl.uniprot.org/uniprot/A0A386HIQ4 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. http://togogenome.org/gene/1604335:DXZ79_RS13580 ^@ http://purl.uniprot.org/uniprot/A0A386HFK8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Cell membrane|||In the C-terminal section; belongs to the complex I 49 kDa subunit family.|||In the N-terminal section; belongs to the complex I 30 kDa subunit family.|||NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1604335:DXZ79_RS11140 ^@ http://purl.uniprot.org/uniprot/A0A386HEH8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SufE family.|||Cytoplasm|||Homodimer. Interacts with SufS.|||Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process. http://togogenome.org/gene/1604335:DXZ79_RS15240 ^@ http://purl.uniprot.org/uniprot/A0A386HGF1 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1604335:DXZ79_RS02490 ^@ http://purl.uniprot.org/uniprot/A0A386HAV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS05200 ^@ http://purl.uniprot.org/uniprot/A0A386HBZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS06570 ^@ http://purl.uniprot.org/uniprot/A0A386HC80 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS04505 ^@ http://purl.uniprot.org/uniprot/A0A386HB69 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS06645 ^@ http://purl.uniprot.org/uniprot/A0A386HD34 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS19435 ^@ http://purl.uniprot.org/uniprot/A0A386HIE6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.|||Cytoplasm|||Monomer.|||The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. http://togogenome.org/gene/1604335:DXZ79_RS13810 ^@ http://purl.uniprot.org/uniprot/A0A8D4SNS3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS17985 ^@ http://purl.uniprot.org/uniprot/A0A8D4STF1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1604335:DXZ79_RS12690 ^@ http://purl.uniprot.org/uniprot/A0A386HFM8 ^@ Function|||Similarity ^@ Belongs to the LpxK family.|||Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). http://togogenome.org/gene/1604335:DXZ79_RS15350 ^@ http://purl.uniprot.org/uniprot/A0A386HH89 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the aldolase class II family. MtnB subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). http://togogenome.org/gene/1604335:DXZ79_RS15605 ^@ http://purl.uniprot.org/uniprot/A0A386HGN4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS09540 ^@ http://purl.uniprot.org/uniprot/A0A8D4N4E9 ^@ Function|||Similarity ^@ Belongs to the bacterial solute-binding protein 9 family.|||Involved in the high-affinity zinc uptake transport system. http://togogenome.org/gene/1604335:DXZ79_RS04830 ^@ http://purl.uniprot.org/uniprot/A0A8D4SM88 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/1604335:DXZ79_RS19745 ^@ http://purl.uniprot.org/uniprot/A0A386HJ60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS07605 ^@ http://purl.uniprot.org/uniprot/A0A386HDB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS19240 ^@ http://purl.uniprot.org/uniprot/A0A386HIU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TsgA family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS15500 ^@ http://purl.uniprot.org/uniprot/A0A8D4N5T7 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/1604335:DXZ79_RS19735 ^@ http://purl.uniprot.org/uniprot/A0A8E3ZHZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS12410 ^@ http://purl.uniprot.org/uniprot/A0A8D4N2U3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbE subfamily.|||Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS00605 ^@ http://purl.uniprot.org/uniprot/A0A386H9E2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1604335:DXZ79_RS11830 ^@ http://purl.uniprot.org/uniprot/A0A386HFD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/1604335:DXZ79_RS00455 ^@ http://purl.uniprot.org/uniprot/A0A386H9F2 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1604335:DXZ79_RS18705 ^@ http://purl.uniprot.org/uniprot/A0A386HI35 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1604335:DXZ79_RS06465 ^@ http://purl.uniprot.org/uniprot/A0A386HCC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS05385 ^@ http://purl.uniprot.org/uniprot/A0A386HBQ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HscB family.|||Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.|||Interacts with HscA and stimulates its ATPase activity. Interacts with IscU. http://togogenome.org/gene/1604335:DXZ79_RS15575 ^@ http://purl.uniprot.org/uniprot/A0A386HH87 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/1604335:DXZ79_RS17345 ^@ http://purl.uniprot.org/uniprot/A0A386HHF6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS14775 ^@ http://purl.uniprot.org/uniprot/A0A386HHH3 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/1604335:DXZ79_RS00445 ^@ http://purl.uniprot.org/uniprot/A0A386H9T0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecB family.|||Cytoplasm|||Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.|||One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. http://togogenome.org/gene/1604335:DXZ79_RS12330 ^@ http://purl.uniprot.org/uniprot/A0A386HEY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS09335 ^@ http://purl.uniprot.org/uniprot/A0A386HDI5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/1604335:DXZ79_RS07525 ^@ http://purl.uniprot.org/uniprot/A0A386HD17 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS11320 ^@ http://purl.uniprot.org/uniprot/A0A386HF88 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1604335:DXZ79_RS04160 ^@ http://purl.uniprot.org/uniprot/A0A8D4MZ97 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dGTPase family. Type 1 subfamily.|||Homotetramer.|||dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs. http://togogenome.org/gene/1604335:DXZ79_RS20145 ^@ http://purl.uniprot.org/uniprot/A0A386HJG6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhE family.|||Cytoplasm|||Necessary for formate dehydrogenase activity. http://togogenome.org/gene/1604335:DXZ79_RS12530 ^@ http://purl.uniprot.org/uniprot/A0A386HF57 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thioester dehydratase family. FabA subfamily.|||Cytoplasm|||Homodimer.|||Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. http://togogenome.org/gene/1604335:DXZ79_RS11430 ^@ http://purl.uniprot.org/uniprot/A0A8E3ZHT3 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/1604335:DXZ79_RS06420 ^@ http://purl.uniprot.org/uniprot/A0A386HCI7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/1604335:DXZ79_RS01160 ^@ http://purl.uniprot.org/uniprot/A0A386H9I3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anaerobic G-3-P dehydrogenase subunit B family.|||Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.|||Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor. http://togogenome.org/gene/1604335:DXZ79_RS07265 ^@ http://purl.uniprot.org/uniprot/A0A8D4N0L7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.|||Binds 1 [4Fe-4S] cluster.|||DNA-dependent ATPase and 5'-3' DNA helicase. http://togogenome.org/gene/1604335:DXZ79_RS00430 ^@ http://purl.uniprot.org/uniprot/A0A386H982 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS13705 ^@ http://purl.uniprot.org/uniprot/A0A386HGE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS06295 ^@ http://purl.uniprot.org/uniprot/A0A386HCX4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1604335:DXZ79_RS02560 ^@ http://purl.uniprot.org/uniprot/A0A8E4BMB5 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS09875 ^@ http://purl.uniprot.org/uniprot/A0A386HES5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS19590 ^@ http://purl.uniprot.org/uniprot/A0A386HIH9 ^@ Function|||Similarity ^@ Belongs to the IolE/MocC family.|||Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol). http://togogenome.org/gene/1604335:DXZ79_RS00240 ^@ http://purl.uniprot.org/uniprot/A0A8D4SQQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS17845 ^@ http://purl.uniprot.org/uniprot/A0A386HIF1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/1604335:DXZ79_RS06770 ^@ http://purl.uniprot.org/uniprot/A0A386HCN1 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/1604335:DXZ79_RS02680 ^@ http://purl.uniprot.org/uniprot/A0A386HAN6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase U32 family. UbiU subfamily.|||Forms an heterodimer with UbiV.|||Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway. http://togogenome.org/gene/1604335:DXZ79_RS16080 ^@ http://purl.uniprot.org/uniprot/A0A386HHI7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS10415 ^@ http://purl.uniprot.org/uniprot/A0A386HEK4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS10375 ^@ http://purl.uniprot.org/uniprot/A0A386HEB0 ^@ Cofactor|||Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1604335:DXZ79_RS02665 ^@ http://purl.uniprot.org/uniprot/A0A386HAT5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. http://togogenome.org/gene/1604335:DXZ79_RS20520 ^@ http://purl.uniprot.org/uniprot/A0A386HJN9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/1604335:DXZ79_RS15055 ^@ http://purl.uniprot.org/uniprot/A0A386HGT3 ^@ Function|||Similarity ^@ Belongs to the nucleoside phosphorylase PpnP family.|||Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. http://togogenome.org/gene/1604335:DXZ79_RS04555 ^@ http://purl.uniprot.org/uniprot/A0A386HB79 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/1604335:DXZ79_RS13610 ^@ http://purl.uniprot.org/uniprot/A0A386HGX3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 5DNU family.|||Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS03200 ^@ http://purl.uniprot.org/uniprot/A0A386HB16 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1604335:DXZ79_RS12575 ^@ http://purl.uniprot.org/uniprot/A0A386HFQ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RlmKL family.|||Cytoplasm|||Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. http://togogenome.org/gene/1604335:DXZ79_RS16320 ^@ http://purl.uniprot.org/uniprot/A0A386HHW7 ^@ Similarity ^@ Belongs to the prokaryotic GSH synthase family. http://togogenome.org/gene/1604335:DXZ79_RS05045 ^@ http://purl.uniprot.org/uniprot/A0A386HBF5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrcB (TC 9.B.71) family.|||Cell membrane|||Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS13005 ^@ http://purl.uniprot.org/uniprot/A0A386HG89 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS08760 ^@ http://purl.uniprot.org/uniprot/A0A386HDW5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FliT family.|||Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.|||Homodimer. Interacts with FliD and FlhC.|||cytosol http://togogenome.org/gene/1604335:DXZ79_RS09950 ^@ http://purl.uniprot.org/uniprot/A0A8E4BMF3 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/1604335:DXZ79_RS13475 ^@ http://purl.uniprot.org/uniprot/A0A8D4SNQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ElaB/YgaM/YqjD family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS02190 ^@ http://purl.uniprot.org/uniprot/A0A386HAU1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1604335:DXZ79_RS15150 ^@ http://purl.uniprot.org/uniprot/A0A8D4SRK3 ^@ Function|||Similarity ^@ Belongs to the FrsA family.|||Catalyzes the hydrolysis of esters. http://togogenome.org/gene/1604335:DXZ79_RS02170 ^@ http://purl.uniprot.org/uniprot/A0A386HAD5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CutA family.|||Binds 1 copper ion per subunit.|||Cytoplasm|||Homotrimer.|||Involved in resistance toward heavy metals. http://togogenome.org/gene/1604335:DXZ79_RS17575 ^@ http://purl.uniprot.org/uniprot/A0A386HI88 ^@ Function|||Similarity ^@ Belongs to the group II decarboxylase family.|||Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria. http://togogenome.org/gene/1604335:DXZ79_RS06755 ^@ http://purl.uniprot.org/uniprot/A0A386HCG6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/1604335:DXZ79_RS11940 ^@ http://purl.uniprot.org/uniprot/A0A386HFF4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/1604335:DXZ79_RS05645 ^@ http://purl.uniprot.org/uniprot/A0A386HBZ7 ^@ Similarity ^@ Belongs to the GppA/Ppx family. http://togogenome.org/gene/1604335:DXZ79_RS12730 ^@ http://purl.uniprot.org/uniprot/A0A8D4N2Y4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS17675 ^@ http://purl.uniprot.org/uniprot/A0A386HHK8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MzrA family.|||Cell inner membrane|||Interacts with EnvZ.|||Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR. http://togogenome.org/gene/1604335:DXZ79_RS16310 ^@ http://purl.uniprot.org/uniprot/A0A386HHL8 ^@ Similarity ^@ Belongs to the EndA/NucM nuclease family. http://togogenome.org/gene/1604335:DXZ79_RS17865 ^@ http://purl.uniprot.org/uniprot/A0A386HIH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS17035 ^@ http://purl.uniprot.org/uniprot/A0A386HI34 ^@ Similarity ^@ Belongs to the type III secretion exporter family. http://togogenome.org/gene/1604335:DXZ79_RS12550 ^@ http://purl.uniprot.org/uniprot/A0A386HFF5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ribosome modulation factor family.|||Cytoplasm|||During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes). http://togogenome.org/gene/1604335:DXZ79_RS12565 ^@ http://purl.uniprot.org/uniprot/A0A8D4N4T1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PqiA family.|||Component of a transport pathway that contributes to membrane integrity.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS08105 ^@ http://purl.uniprot.org/uniprot/A0A386HD87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fimbrial export usher family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS02575 ^@ http://purl.uniprot.org/uniprot/A0A386HA61 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/1604335:DXZ79_RS16165 ^@ http://purl.uniprot.org/uniprot/A0A386HHD0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1604335:DXZ79_RS04335 ^@ http://purl.uniprot.org/uniprot/A0A386HBT9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.|||Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS12710 ^@ http://purl.uniprot.org/uniprot/A0A386HF49 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family.|||Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. http://togogenome.org/gene/1604335:DXZ79_RS11715 ^@ http://purl.uniprot.org/uniprot/A0A386HFW2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CopD family.|||Cell inner membrane|||Involved in copper resistance. Appears to be involved in copper uptake.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS11870 ^@ http://purl.uniprot.org/uniprot/A0A386HFZ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the lipid A palmitoyltransferase family.|||Cell outer membrane|||Homodimer.|||Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors. http://togogenome.org/gene/1604335:DXZ79_RS14540 ^@ http://purl.uniprot.org/uniprot/A0A386HH04 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS03795 ^@ http://purl.uniprot.org/uniprot/A0A386HB62 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. FtsI subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.|||Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS19170 ^@ http://purl.uniprot.org/uniprot/A0A8E4DEB8 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. http://togogenome.org/gene/1604335:DXZ79_RS18210 ^@ http://purl.uniprot.org/uniprot/A0A386HID4 ^@ Function|||Similarity|||Subunit ^@ Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.|||Belongs to the transcriptional regulatory Fis family.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS01025 ^@ http://purl.uniprot.org/uniprot/A0A386HA19 ^@ Function|||Similarity ^@ Belongs to the uroporphyrinogen-III synthase family.|||Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. http://togogenome.org/gene/1604335:DXZ79_RS09655 ^@ http://purl.uniprot.org/uniprot/A0A386HEA7 ^@ Similarity ^@ Belongs to the UPF0260 family. http://togogenome.org/gene/1604335:DXZ79_RS17595 ^@ http://purl.uniprot.org/uniprot/A0A8D4N7S0 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/1604335:DXZ79_RS14770 ^@ http://purl.uniprot.org/uniprot/A0A386HGN1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/1604335:DXZ79_RS20150 ^@ http://purl.uniprot.org/uniprot/A0A386HJM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the formate dehydrogenase gamma subunit family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS13865 ^@ http://purl.uniprot.org/uniprot/A0A8D4N5L9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.|||Cytoplasm|||In the C-terminal section; belongs to the DAO family.|||In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family. http://togogenome.org/gene/1604335:DXZ79_RS13745 ^@ http://purl.uniprot.org/uniprot/A0A386HFN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS15805 ^@ http://purl.uniprot.org/uniprot/A0A386HHD5 ^@ Function|||Similarity ^@ Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.|||Belongs to the Nudix hydrolase family. RppH subfamily. http://togogenome.org/gene/1604335:DXZ79_RS13465 ^@ http://purl.uniprot.org/uniprot/A0A386HFH3 ^@ Function|||Similarity ^@ Belongs to the isochorismate synthase family.|||Catalyzes the conversion of chorismate to isochorismate. http://togogenome.org/gene/1604335:DXZ79_RS03630 ^@ http://purl.uniprot.org/uniprot/A0A386HBI3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/1604335:DXZ79_RS12705 ^@ http://purl.uniprot.org/uniprot/A0A386HFR9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/1604335:DXZ79_RS14880 ^@ http://purl.uniprot.org/uniprot/A0A8D4N149 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/1604335:DXZ79_RS09190 ^@ http://purl.uniprot.org/uniprot/A0A386HE04 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS09675 ^@ http://purl.uniprot.org/uniprot/A0A386HEA3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.|||Cell membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/1604335:DXZ79_RS06105 ^@ http://purl.uniprot.org/uniprot/A0A386HBY3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial glucokinase family.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS07325 ^@ http://purl.uniprot.org/uniprot/A0A386HCI6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. Tam family.|||Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS16670 ^@ http://purl.uniprot.org/uniprot/A0A386HIF5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1604335:DXZ79_RS19365 ^@ http://purl.uniprot.org/uniprot/A0A386HIV9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.|||Binds 1 Mn(2+) ion per subunit.|||Cytoplasm|||Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS11765 ^@ http://purl.uniprot.org/uniprot/A0A386HFX2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. DbpA subfamily.|||Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.|||Cytoplasm|||DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. http://togogenome.org/gene/1604335:DXZ79_RS05995 ^@ http://purl.uniprot.org/uniprot/A0A386HCP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CysZ family.|||Cell inner membrane|||High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway. http://togogenome.org/gene/1604335:DXZ79_RS04250 ^@ http://purl.uniprot.org/uniprot/A0A386HBK4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.|||Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Binds 1 siroheme per subunit.|||Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. http://togogenome.org/gene/1604335:DXZ79_RS08985 ^@ http://purl.uniprot.org/uniprot/A0A386HDY1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Cell inner membrane|||Membrane|||This protein catalyzes the committed step to the synthesis of the acidic phospholipids. http://togogenome.org/gene/1604335:DXZ79_RS20295 ^@ http://purl.uniprot.org/uniprot/A0A386HJJ2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.|||Belongs to the small heat shock protein (HSP20) family.|||Cytoplasm|||Homodimer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to oligomers at high temperatures or high ionic concentrations. The decrease in size of the multimers is accompanied by an increase in chaperone activity.|||The N- and C-terminal flexible termini are involved in oligomerization and in the binding of non-native substrate proteins, and are essential for chaperone activity. http://togogenome.org/gene/1604335:DXZ79_RS15590 ^@ http://purl.uniprot.org/uniprot/A0A386HH95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS14680 ^@ http://purl.uniprot.org/uniprot/A0A386HG52 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/1604335:DXZ79_RS06410 ^@ http://purl.uniprot.org/uniprot/A0A386HCZ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transpeptidase family. MrdA subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall.|||Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS04120 ^@ http://purl.uniprot.org/uniprot/A0A8D4N230 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS17145 ^@ http://purl.uniprot.org/uniprot/A0A386HI57 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1604335:DXZ79_RS11045 ^@ http://purl.uniprot.org/uniprot/A0A386HFD7 ^@ Similarity ^@ Belongs to the glyoxalase I family. http://togogenome.org/gene/1604335:DXZ79_RS17385 ^@ http://purl.uniprot.org/uniprot/A0A8D4N3S5 ^@ Cofactor|||Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ A single active site specifically recognizes both ATP and CTP and is responsible for their addition.|||Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.|||Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.|||Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.|||Magnesium is required for nucleotidyltransferase activity.|||Monomer. Can also form homodimers and oligomers.|||Nickel for phosphatase activity. http://togogenome.org/gene/1604335:DXZ79_RS17980 ^@ http://purl.uniprot.org/uniprot/A0A386HIF4 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1604335:DXZ79_RS02855 ^@ http://purl.uniprot.org/uniprot/A0A386HAU8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RraB family.|||Cytoplasm|||Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.|||Interacts with the C-terminal region of Rne. http://togogenome.org/gene/1604335:DXZ79_RS01455 ^@ http://purl.uniprot.org/uniprot/A0A386HA62 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TrkH potassium transport family.|||Cell inner membrane|||Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS16990 ^@ http://purl.uniprot.org/uniprot/A0A386HHE1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Cell inner membrane|||FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS09690 ^@ http://purl.uniprot.org/uniprot/A0A386HE84 ^@ Function|||Similarity ^@ Belongs to the DadA oxidoreductase family.|||Oxidative deamination of D-amino acids. http://togogenome.org/gene/1604335:DXZ79_RS16155 ^@ http://purl.uniprot.org/uniprot/A0A386HHT2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1604335:DXZ79_RS11805 ^@ http://purl.uniprot.org/uniprot/A0A8D4SR22 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homodimer.|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport. http://togogenome.org/gene/1604335:DXZ79_RS12085 ^@ http://purl.uniprot.org/uniprot/A0A8D4N2Q2 ^@ Function|||Similarity ^@ Belongs to the ROK (NagC/XylR) family. NagK subfamily.|||Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. http://togogenome.org/gene/1604335:DXZ79_RS00155 ^@ http://purl.uniprot.org/uniprot/A0A386H9Q5 ^@ Function|||Similarity|||Subunit ^@ A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.|||Belongs to the YihI family.|||Interacts with Der. http://togogenome.org/gene/1604335:DXZ79_RS13390 ^@ http://purl.uniprot.org/uniprot/A0A386HGT1 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/1604335:DXZ79_RS19930 ^@ http://purl.uniprot.org/uniprot/A0A8E3ZHZ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS18790 ^@ http://purl.uniprot.org/uniprot/A0A386HI32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic pantothenate kinase family.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS15640 ^@ http://purl.uniprot.org/uniprot/A0A386HHA8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family.|||Cytoplasm|||Homotrimer. http://togogenome.org/gene/1604335:DXZ79_RS01405 ^@ http://purl.uniprot.org/uniprot/A0A8D4N153 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1604335:DXZ79_RS16325 ^@ http://purl.uniprot.org/uniprot/A0A386HH27 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/1604335:DXZ79_RS14870 ^@ http://purl.uniprot.org/uniprot/A0A386HH62 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/1604335:DXZ79_RS12120 ^@ http://purl.uniprot.org/uniprot/A0A386HEU2 ^@ Similarity ^@ Belongs to the UPF0227 family. http://togogenome.org/gene/1604335:DXZ79_RS04090 ^@ http://purl.uniprot.org/uniprot/A0A8D4N3G3 ^@ Similarity ^@ Belongs to the SfsA family. http://togogenome.org/gene/1604335:DXZ79_RS20095 ^@ http://purl.uniprot.org/uniprot/A0A386HJL9 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate. http://togogenome.org/gene/1604335:DXZ79_RS16355 ^@ http://purl.uniprot.org/uniprot/A0A386HGZ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS15060 ^@ http://purl.uniprot.org/uniprot/A0A386HHL4 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family. AroL subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer.|||The LID domain closes over the active site upon ATP binding. http://togogenome.org/gene/1604335:DXZ79_RS04850 ^@ http://purl.uniprot.org/uniprot/A0A386HBU2 ^@ Function|||Subunit ^@ DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.|||The DNA polymerase holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential subassemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core (subunits alpha,epsilon and theta) contains the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. This complex contains delta, delta', psi and chi, and copies of either or both of two different DnaX proteins, gamma and tau. http://togogenome.org/gene/1604335:DXZ79_RS13635 ^@ http://purl.uniprot.org/uniprot/A0A386HFL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0208 family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS09345 ^@ http://purl.uniprot.org/uniprot/A0A386HE42 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LolB family.|||Cell outer membrane|||Membrane|||Monomer.|||Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. http://togogenome.org/gene/1604335:DXZ79_RS04875 ^@ http://purl.uniprot.org/uniprot/A0A386HBG0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1604335:DXZ79_RS17300 ^@ http://purl.uniprot.org/uniprot/A0A386HI36 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family. ParE type 1 subfamily.|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/1604335:DXZ79_RS18660 ^@ http://purl.uniprot.org/uniprot/A0A386HL23 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS10100 ^@ http://purl.uniprot.org/uniprot/A0A386HEW9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/1604335:DXZ79_RS01150 ^@ http://purl.uniprot.org/uniprot/A0A386H9X1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS11290 ^@ http://purl.uniprot.org/uniprot/A0A386HET0 ^@ Function|||Similarity ^@ Belongs to the glutathione peroxidase family. BtuE subfamily.|||Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent. http://togogenome.org/gene/1604335:DXZ79_RS10905 ^@ http://purl.uniprot.org/uniprot/A0A8D4SNA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 5 family.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS10775 ^@ http://purl.uniprot.org/uniprot/A0A386HE68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS10870 ^@ http://purl.uniprot.org/uniprot/A0A8E4BJQ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS13080 ^@ http://purl.uniprot.org/uniprot/A0A386HFU4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS04670 ^@ http://purl.uniprot.org/uniprot/A0A386HBL4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the LuxS family.|||Binds 1 Fe cation per subunit.|||Homodimer.|||Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). http://togogenome.org/gene/1604335:DXZ79_RS18855 ^@ http://purl.uniprot.org/uniprot/A0A8D4SRU5 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/1604335:DXZ79_RS01260 ^@ http://purl.uniprot.org/uniprot/A0A386H9Z0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/1604335:DXZ79_RS05805 ^@ http://purl.uniprot.org/uniprot/A0A386HCC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS00560 ^@ http://purl.uniprot.org/uniprot/A0A386H9U8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ZapB family.|||Cytoplasm|||Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.|||Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. http://togogenome.org/gene/1604335:DXZ79_RS16235 ^@ http://purl.uniprot.org/uniprot/A0A386HHE9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscS (TC 1.A.23) family.|||Cell inner membrane|||Homoheptamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS10630 ^@ http://purl.uniprot.org/uniprot/A0A386HES3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS15785 ^@ http://purl.uniprot.org/uniprot/A0A386HH74 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS13265 ^@ http://purl.uniprot.org/uniprot/A0A386HFT1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1604335:DXZ79_RS07565 ^@ http://purl.uniprot.org/uniprot/A0A386HDH9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS18940 ^@ http://purl.uniprot.org/uniprot/A0A386HJ61 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1604335:DXZ79_RS20365 ^@ http://purl.uniprot.org/uniprot/A0A386HJK6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/1604335:DXZ79_RS00545 ^@ http://purl.uniprot.org/uniprot/A0A386H9D6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS16220 ^@ http://purl.uniprot.org/uniprot/A0A386HH08 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LysR transcriptional regulatory family.|||Controls the transcription of genes involved in arginine and lysine metabolism.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS03490 ^@ http://purl.uniprot.org/uniprot/A0A386HAM5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 1 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/1604335:DXZ79_RS18080 ^@ http://purl.uniprot.org/uniprot/A0A386HHS0 ^@ Similarity ^@ Belongs to the barstar family. http://togogenome.org/gene/1604335:DXZ79_RS07600 ^@ http://purl.uniprot.org/uniprot/A0A8D4N0Q3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS05135 ^@ http://purl.uniprot.org/uniprot/A0A386HBQ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/1604335:DXZ79_RS15865 ^@ http://purl.uniprot.org/uniprot/A0A386HHN3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS16195 ^@ http://purl.uniprot.org/uniprot/A0A386HGX6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.|||Belongs to the ZapA family. Type 1 subfamily.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/1604335:DXZ79_RS11810 ^@ http://purl.uniprot.org/uniprot/A0A386HEU3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS04435 ^@ http://purl.uniprot.org/uniprot/A0A386HBM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS16775 ^@ http://purl.uniprot.org/uniprot/A0A8D4N6K6 ^@ Function|||Similarity ^@ Belongs to the carbamoyltransferase HypF family.|||Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. http://togogenome.org/gene/1604335:DXZ79_RS19485 ^@ http://purl.uniprot.org/uniprot/A0A386HIG1 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/1604335:DXZ79_RS04990 ^@ http://purl.uniprot.org/uniprot/A0A386HBE5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease beta subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1604335:DXZ79_RS02600 ^@ http://purl.uniprot.org/uniprot/A0A386HAE9 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/1604335:DXZ79_RS19020 ^@ http://purl.uniprot.org/uniprot/A0A386HI85 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/1604335:DXZ79_RS14590 ^@ http://purl.uniprot.org/uniprot/A0A386HH14 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/1604335:DXZ79_RS16955 ^@ http://purl.uniprot.org/uniprot/A0A386HHR8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/1604335:DXZ79_RS01175 ^@ http://purl.uniprot.org/uniprot/A0A386HA46 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell inner membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/1604335:DXZ79_RS13985 ^@ http://purl.uniprot.org/uniprot/A0A386HG92 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/1604335:DXZ79_RS18950 ^@ http://purl.uniprot.org/uniprot/A0A386HIN7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1604335:DXZ79_RS01040 ^@ http://purl.uniprot.org/uniprot/A0A386HA42 ^@ Function|||Similarity ^@ Belongs to the frataxin family.|||Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. http://togogenome.org/gene/1604335:DXZ79_RS02545 ^@ http://purl.uniprot.org/uniprot/A0A386HAD8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1604335:DXZ79_RS02225 ^@ http://purl.uniprot.org/uniprot/A0A386HAE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS20505 ^@ http://purl.uniprot.org/uniprot/A0A386HJN3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/1604335:DXZ79_RS18880 ^@ http://purl.uniprot.org/uniprot/A0A386HIV0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell inner membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS12975 ^@ http://purl.uniprot.org/uniprot/A0A386HFX0 ^@ Subunit ^@ Monomer. http://togogenome.org/gene/1604335:DXZ79_RS19765 ^@ http://purl.uniprot.org/uniprot/A0A386HJ24 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/1604335:DXZ79_RS05605 ^@ http://purl.uniprot.org/uniprot/A0A386HBU4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.|||Cell inner membrane|||Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtB forms a heteromultimer with MdtC. http://togogenome.org/gene/1604335:DXZ79_RS04705 ^@ http://purl.uniprot.org/uniprot/A0A386HBI1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/1604335:DXZ79_RS10965 ^@ http://purl.uniprot.org/uniprot/A0A8D4N4P7 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/1604335:DXZ79_RS03695 ^@ http://purl.uniprot.org/uniprot/A0A8D4SPC9 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/1604335:DXZ79_RS20115 ^@ http://purl.uniprot.org/uniprot/A0A386HK38 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acyltransferase 3 family.|||Cell inner membrane|||Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units. http://togogenome.org/gene/1604335:DXZ79_RS03525 ^@ http://purl.uniprot.org/uniprot/A0A386HBG5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell inner membrane|||Cell membrane|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/1604335:DXZ79_RS13340 ^@ http://purl.uniprot.org/uniprot/A0A386HG27 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1604335:DXZ79_RS07625 ^@ http://purl.uniprot.org/uniprot/A0A386HD36 ^@ Similarity ^@ Belongs to the UPF0053 family. http://togogenome.org/gene/1604335:DXZ79_RS14685 ^@ http://purl.uniprot.org/uniprot/A0A386HGS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS18545 ^@ http://purl.uniprot.org/uniprot/A0A386HIJ2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS03190 ^@ http://purl.uniprot.org/uniprot/A0A8D4MZF3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arginine deiminase family.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS16840 ^@ http://purl.uniprot.org/uniprot/A0A386HHA7 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/1604335:DXZ79_RS07075 ^@ http://purl.uniprot.org/uniprot/A0A386HCS0 ^@ Similarity ^@ Belongs to the MoaD family. http://togogenome.org/gene/1604335:DXZ79_RS16190 ^@ http://purl.uniprot.org/uniprot/A0A386HGW4 ^@ Similarity ^@ Belongs to the UPF0149 family. http://togogenome.org/gene/1604335:DXZ79_RS12635 ^@ http://purl.uniprot.org/uniprot/A0A386HF83 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/1604335:DXZ79_RS05850 ^@ http://purl.uniprot.org/uniprot/A0A386HBU7 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NapC/NirT/NrfH family.|||Binds 4 heme groups per subunit.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS08780 ^@ http://purl.uniprot.org/uniprot/A0A386HDM1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sigma-70 factor family. FliA subfamily.|||Cytoplasm|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes. http://togogenome.org/gene/1604335:DXZ79_RS17400 ^@ http://purl.uniprot.org/uniprot/A0A386HI66 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/1604335:DXZ79_RS08720 ^@ http://purl.uniprot.org/uniprot/A0A386HDD4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Cell inner membrane|||FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS11985 ^@ http://purl.uniprot.org/uniprot/A0A386HEW7 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1604335:DXZ79_RS05585 ^@ http://purl.uniprot.org/uniprot/A0A386HC59 ^@ Similarity ^@ Belongs to the UPF0339 family. Duplicated subfamily. http://togogenome.org/gene/1604335:DXZ79_RS18645 ^@ http://purl.uniprot.org/uniprot/A0A386HIT5 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1604335:DXZ79_RS20300 ^@ http://purl.uniprot.org/uniprot/A0A8E3ZHJ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.|||Belongs to the small heat shock protein (HSP20) family.|||Cytoplasm|||Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations. http://togogenome.org/gene/1604335:DXZ79_RS03985 ^@ http://purl.uniprot.org/uniprot/A0A386HAY0 ^@ Similarity ^@ Belongs to the UPF0231 family. http://togogenome.org/gene/1604335:DXZ79_RS20190 ^@ http://purl.uniprot.org/uniprot/A0A386HIS9 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1604335:DXZ79_RS01215 ^@ http://purl.uniprot.org/uniprot/A0A386H9M1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/1604335:DXZ79_RS13995 ^@ http://purl.uniprot.org/uniprot/A0A8D4SSU8 ^@ Similarity ^@ Belongs to the UPF0115 family. http://togogenome.org/gene/1604335:DXZ79_RS09965 ^@ http://purl.uniprot.org/uniprot/A0A386HEK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0259 family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS04080 ^@ http://purl.uniprot.org/uniprot/A0A8D4N2K6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon. http://togogenome.org/gene/1604335:DXZ79_RS00780 ^@ http://purl.uniprot.org/uniprot/A0A8D4N0Y2 ^@ Function|||Similarity ^@ Belongs to the LysR transcriptional regulatory family.|||Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon. http://togogenome.org/gene/1604335:DXZ79_RS11345 ^@ http://purl.uniprot.org/uniprot/A0A386HFR6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS05380 ^@ http://purl.uniprot.org/uniprot/A0A386HC42 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HesB/IscA family.|||Binds 2 iron ions per dimer. The dimer may bind additional iron ions.|||Homodimer; may form tetramers and higher multimers.|||Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB. http://togogenome.org/gene/1604335:DXZ79_RS02890 ^@ http://purl.uniprot.org/uniprot/A0A386HAX3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptF/LptG family.|||Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).|||Membrane|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. http://togogenome.org/gene/1604335:DXZ79_RS19505 ^@ http://purl.uniprot.org/uniprot/A0A8D4N7L1 ^@ Function|||Similarity ^@ Belongs to the glycosyl hydrolase 13 family.|||Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin. http://togogenome.org/gene/1604335:DXZ79_RS05890 ^@ http://purl.uniprot.org/uniprot/A0A386HCC7 ^@ Similarity ^@ Belongs to the acetyltransferase family. YpeA subfamily. http://togogenome.org/gene/1604335:DXZ79_RS02605 ^@ http://purl.uniprot.org/uniprot/A0A386HAS6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS03760 ^@ http://purl.uniprot.org/uniprot/A0A386HAT9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1604335:DXZ79_RS17360 ^@ http://purl.uniprot.org/uniprot/A0A386HI91 ^@ Function|||Similarity|||Subunit ^@ Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.|||Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.|||Homodimer.|||In the C-terminal section; belongs to the cytidylyltransferase family.|||In the N-terminal section; belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/1604335:DXZ79_RS19935 ^@ http://purl.uniprot.org/uniprot/A0A386HJ54 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS14210 ^@ http://purl.uniprot.org/uniprot/A0A386HGV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS00280 ^@ http://purl.uniprot.org/uniprot/A0A386H9T7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS00135 ^@ http://purl.uniprot.org/uniprot/A0A386H938 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbA subfamily.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS03725 ^@ http://purl.uniprot.org/uniprot/A0A386HBH1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1604335:DXZ79_RS06820 ^@ http://purl.uniprot.org/uniprot/A0A386HCP1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Pal lipoprotein family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/1604335:DXZ79_RS03905 ^@ http://purl.uniprot.org/uniprot/A0A386HBM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS03335 ^@ http://purl.uniprot.org/uniprot/A0A386HB34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0391 family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS14740 ^@ http://purl.uniprot.org/uniprot/A0A386HG63 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS10760 ^@ http://purl.uniprot.org/uniprot/A0A386HF84 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1604335:DXZ79_RS09295 ^@ http://purl.uniprot.org/uniprot/A0A386HE90 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/1604335:DXZ79_RS05040 ^@ http://purl.uniprot.org/uniprot/A0A386HJS2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrcB (TC 9.B.71) family.|||Cell membrane|||Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS07970 ^@ http://purl.uniprot.org/uniprot/A0A386HD95 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CbiN family.|||Cell membrane|||Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. http://togogenome.org/gene/1604335:DXZ79_RS06080 ^@ http://purl.uniprot.org/uniprot/A0A8D4N0A1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NRAMP family.|||Cell membrane|||H(+)-stimulated, divalent metal cation uptake system. http://togogenome.org/gene/1604335:DXZ79_RS13270 ^@ http://purl.uniprot.org/uniprot/A0A386HG19 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS07530 ^@ http://purl.uniprot.org/uniprot/A0A8D4SRG7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS17780 ^@ http://purl.uniprot.org/uniprot/A0A386HL09 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LpoA family.|||Interacts with PBP1a.|||Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). http://togogenome.org/gene/1604335:DXZ79_RS04845 ^@ http://purl.uniprot.org/uniprot/A0A386HBK2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS05520 ^@ http://purl.uniprot.org/uniprot/A0A386HBY0 ^@ Cofactor ^@ Binds 3 heme c groups covalently per subunit. http://togogenome.org/gene/1604335:DXZ79_RS14920 ^@ http://purl.uniprot.org/uniprot/A0A386HH15 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/1604335:DXZ79_RS02685 ^@ http://purl.uniprot.org/uniprot/A0A386HAR7 ^@ Function|||Similarity ^@ Belongs to the UbiT family.|||Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor. http://togogenome.org/gene/1604335:DXZ79_RS14890 ^@ http://purl.uniprot.org/uniprot/A0A386HGR3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS03565 ^@ http://purl.uniprot.org/uniprot/A0A386HBE4 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1604335:DXZ79_RS19290 ^@ http://purl.uniprot.org/uniprot/A0A386HJQ7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DamX family.|||Cell inner membrane|||Non-essential cell division protein.|||The SPOR domain binds septal peptidoglycans and is required to target DamX to the septal ring. http://togogenome.org/gene/1604335:DXZ79_RS20175 ^@ http://purl.uniprot.org/uniprot/A0A8E4DED3 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1604335:DXZ79_RS20375 ^@ http://purl.uniprot.org/uniprot/A0A386HJW7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/1604335:DXZ79_RS09430 ^@ http://purl.uniprot.org/uniprot/A0A386HEI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS00940 ^@ http://purl.uniprot.org/uniprot/A0A386H9H6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.|||Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS05650 ^@ http://purl.uniprot.org/uniprot/A0A386HC67 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/1604335:DXZ79_RS05375 ^@ http://purl.uniprot.org/uniprot/A0A386HBY6 ^@ Function|||Similarity ^@ A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.|||Belongs to the NifU family. http://togogenome.org/gene/1604335:DXZ79_RS17140 ^@ http://purl.uniprot.org/uniprot/A0A386HI09 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1604335:DXZ79_RS18140 ^@ http://purl.uniprot.org/uniprot/A0A386HII4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Cell inner membrane|||Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS15990 ^@ http://purl.uniprot.org/uniprot/A0A386HHA0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS02635 ^@ http://purl.uniprot.org/uniprot/A0A386HA75 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/1604335:DXZ79_RS13715 ^@ http://purl.uniprot.org/uniprot/A0A386HFR2 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS13845 ^@ http://purl.uniprot.org/uniprot/A0A386HGB3 ^@ Similarity ^@ Belongs to the porin LamB (TC 1.B.3) family. http://togogenome.org/gene/1604335:DXZ79_RS16135 ^@ http://purl.uniprot.org/uniprot/A0A386HGV3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA-modifying YgfZ family.|||Cytoplasm|||Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication. http://togogenome.org/gene/1604335:DXZ79_RS08005 ^@ http://purl.uniprot.org/uniprot/A0A8D4SMR9 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/1604335:DXZ79_RS19490 ^@ http://purl.uniprot.org/uniprot/A0A386HIF6 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/1604335:DXZ79_RS17920 ^@ http://purl.uniprot.org/uniprot/A0A386HIE5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the KdsC family.|||Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.|||Homotetramer. http://togogenome.org/gene/1604335:DXZ79_RS06385 ^@ http://purl.uniprot.org/uniprot/A0A8D4N3H4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/1604335:DXZ79_RS17195 ^@ http://purl.uniprot.org/uniprot/A0A386HI20 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1604335:DXZ79_RS18900 ^@ http://purl.uniprot.org/uniprot/A0A386HIM9 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1604335:DXZ79_RS04180 ^@ http://purl.uniprot.org/uniprot/A0A386HB86 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/1604335:DXZ79_RS02310 ^@ http://purl.uniprot.org/uniprot/A0A386HAV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS12540 ^@ http://purl.uniprot.org/uniprot/A0A386HGB8 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/1604335:DXZ79_RS01390 ^@ http://purl.uniprot.org/uniprot/A0A8D4SLP4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC1 family. UbiB subfamily.|||Cell membrane|||Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS18735 ^@ http://purl.uniprot.org/uniprot/A0A386HIL1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NusG family.|||Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.|||Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination. http://togogenome.org/gene/1604335:DXZ79_RS18725 ^@ http://purl.uniprot.org/uniprot/A0A386HJ33 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1604335:DXZ79_RS17075 ^@ http://purl.uniprot.org/uniprot/A0A8E4DFB4 ^@ Similarity ^@ Belongs to the isochorismate synthase family. http://togogenome.org/gene/1604335:DXZ79_RS19385 ^@ http://purl.uniprot.org/uniprot/A0A386HJ36 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family. GreB subfamily.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length. http://togogenome.org/gene/1604335:DXZ79_RS00980 ^@ http://purl.uniprot.org/uniprot/A0A386H9T9 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 26 family.|||Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis. http://togogenome.org/gene/1604335:DXZ79_RS07360 ^@ http://purl.uniprot.org/uniprot/A0A386HDE0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS00465 ^@ http://purl.uniprot.org/uniprot/A0A8D4SLJ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Cytoplasm|||Homodimer.|||Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. http://togogenome.org/gene/1604335:DXZ79_RS08580 ^@ http://purl.uniprot.org/uniprot/A0A386HD59 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/1604335:DXZ79_RS05480 ^@ http://purl.uniprot.org/uniprot/A0A386HCF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS13010 ^@ http://purl.uniprot.org/uniprot/A0A386HFF1 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/1604335:DXZ79_RS03160 ^@ http://purl.uniprot.org/uniprot/A0A386HJT9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. AI-2 autoinducer porter (TC 3.A.1.2.8) family.|||Cell inner membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/1604335:DXZ79_RS02215 ^@ http://purl.uniprot.org/uniprot/A0A386HAL2 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.|||May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA. http://togogenome.org/gene/1604335:DXZ79_RS09630 ^@ http://purl.uniprot.org/uniprot/A0A386HDT7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/1604335:DXZ79_RS10090 ^@ http://purl.uniprot.org/uniprot/A0A386HE02 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/1604335:DXZ79_RS11690 ^@ http://purl.uniprot.org/uniprot/A0A386HFF3 ^@ Similarity ^@ Belongs to the RelB/DinJ antitoxin family. http://togogenome.org/gene/1604335:DXZ79_RS13675 ^@ http://purl.uniprot.org/uniprot/A0A386HG51 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1604335:DXZ79_RS15745 ^@ http://purl.uniprot.org/uniprot/A0A386HGN9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetyltransferase family. ArgA subfamily.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/1604335:DXZ79_RS03855 ^@ http://purl.uniprot.org/uniprot/A0A386HB73 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/1604335:DXZ79_RS14505 ^@ http://purl.uniprot.org/uniprot/A0A386HGJ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS17685 ^@ http://purl.uniprot.org/uniprot/A0A386HHL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ElaB/YgaM/YqjD family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS00730 ^@ http://purl.uniprot.org/uniprot/A0A386H9X8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.|||Cell outer membrane|||Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS17850 ^@ http://purl.uniprot.org/uniprot/A0A386HHN4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1604335:DXZ79_RS18470 ^@ http://purl.uniprot.org/uniprot/A0A386HIH7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS18375 ^@ http://purl.uniprot.org/uniprot/A0A386HIP5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS08265 ^@ http://purl.uniprot.org/uniprot/A0A386HDD8 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS06620 ^@ http://purl.uniprot.org/uniprot/A0A386HC88 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SeqA family.|||Cytoplasm|||Homodimer. Polymerizes to form helical filaments.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. http://togogenome.org/gene/1604335:DXZ79_RS07705 ^@ http://purl.uniprot.org/uniprot/A0A386HDA0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/1604335:DXZ79_RS08805 ^@ http://purl.uniprot.org/uniprot/A0A386HD96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS09240 ^@ http://purl.uniprot.org/uniprot/A0A386HE12 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.|||Binds 1 zinc ion per subunit.|||Transforms N(2)-succinylglutamate into succinate and glutamate. http://togogenome.org/gene/1604335:DXZ79_RS19460 ^@ http://purl.uniprot.org/uniprot/A0A386HIX7 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Activated by ATP and maltotriose, which are both required for DNA binding.|||Belongs to the MalT family.|||Monomer in solution. Oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.|||Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box. http://togogenome.org/gene/1604335:DXZ79_RS15030 ^@ http://purl.uniprot.org/uniprot/A0A386HK08 ^@ Function ^@ This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited. http://togogenome.org/gene/1604335:DXZ79_RS20490 ^@ http://purl.uniprot.org/uniprot/A0A8E4BM75 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS08800 ^@ http://purl.uniprot.org/uniprot/A0A386HDA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS02735 ^@ http://purl.uniprot.org/uniprot/A0A386HAP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS18970 ^@ http://purl.uniprot.org/uniprot/A0A386HI75 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/1604335:DXZ79_RS00805 ^@ http://purl.uniprot.org/uniprot/A0A386H9W4 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1604335:DXZ79_RS06005 ^@ http://purl.uniprot.org/uniprot/A0A386HCE6 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS10685 ^@ http://purl.uniprot.org/uniprot/A0A386HEW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS13410 ^@ http://purl.uniprot.org/uniprot/A0A386HFG4 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/1604335:DXZ79_RS15370 ^@ http://purl.uniprot.org/uniprot/A0A386HGZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS01185 ^@ http://purl.uniprot.org/uniprot/A0A386H9S2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS06775 ^@ http://purl.uniprot.org/uniprot/A0A386HCS4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS13565 ^@ http://purl.uniprot.org/uniprot/A0A386HK80 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the complex I 75 kDa subunit family.|||Binds 1 [2Fe-2S] cluster per subunit.|||Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1604335:DXZ79_RS09805 ^@ http://purl.uniprot.org/uniprot/A0A8E4BMT4 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/1604335:DXZ79_RS19465 ^@ http://purl.uniprot.org/uniprot/A0A386HJT5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GlpE family.|||Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS01630 ^@ http://purl.uniprot.org/uniprot/A0A386HAD0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS09180 ^@ http://purl.uniprot.org/uniprot/A0A386HDF4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS13020 ^@ http://purl.uniprot.org/uniprot/A0A386HFT5 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1604335:DXZ79_RS14520 ^@ http://purl.uniprot.org/uniprot/A0A386HG17 ^@ Function|||Similarity ^@ Belongs to the carbohydrate kinase PfkB family.|||Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively. http://togogenome.org/gene/1604335:DXZ79_RS10850 ^@ http://purl.uniprot.org/uniprot/A0A386HEZ3 ^@ Similarity ^@ Belongs to the MbcT/ParT/Res family. http://togogenome.org/gene/1604335:DXZ79_RS12260 ^@ http://purl.uniprot.org/uniprot/A0A386HG67 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1604335:DXZ79_RS12695 ^@ http://purl.uniprot.org/uniprot/A0A386HGF8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS18870 ^@ http://purl.uniprot.org/uniprot/A0A386HI54 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Cytoplasm|||Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. http://togogenome.org/gene/1604335:DXZ79_RS17700 ^@ http://purl.uniprot.org/uniprot/A0A386HIK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS20460 ^@ http://purl.uniprot.org/uniprot/A0A386HIX9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. http://togogenome.org/gene/1604335:DXZ79_RS00380 ^@ http://purl.uniprot.org/uniprot/A0A386H9B1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1604335:DXZ79_RS12205 ^@ http://purl.uniprot.org/uniprot/A0A386HFF2 ^@ Function|||Similarity ^@ Belongs to the transglycosylase MltG family.|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/1604335:DXZ79_RS05125 ^@ http://purl.uniprot.org/uniprot/A0A386HC05 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS13105 ^@ http://purl.uniprot.org/uniprot/A0A386HFE1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/1604335:DXZ79_RS10670 ^@ http://purl.uniprot.org/uniprot/A0A386HE51 ^@ Function|||Similarity ^@ Belongs to the AlaDH/PNT family.|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/1604335:DXZ79_RS06120 ^@ http://purl.uniprot.org/uniprot/A0A386HCU4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS18460 ^@ http://purl.uniprot.org/uniprot/A0A386HIZ0 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/1604335:DXZ79_RS02080 ^@ http://purl.uniprot.org/uniprot/A0A8D4N1X9 ^@ Similarity ^@ Belongs to the transposase 8 family. http://togogenome.org/gene/1604335:DXZ79_RS08695 ^@ http://purl.uniprot.org/uniprot/A0A386HDV8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell inner membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS05910 ^@ http://purl.uniprot.org/uniprot/A0A8D4N346 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/1604335:DXZ79_RS11555 ^@ http://purl.uniprot.org/uniprot/A0A386HF86 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/1604335:DXZ79_RS15835 ^@ http://purl.uniprot.org/uniprot/A0A386HH83 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Cell membrane|||In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.|||In the N-terminal section; belongs to the 2-acyl-GPE acetyltransferase family.|||Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1. http://togogenome.org/gene/1604335:DXZ79_RS06965 ^@ http://purl.uniprot.org/uniprot/A0A386HCQ1 ^@ Cofactor|||Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.|||Binds 1 Fe cation per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1604335:DXZ79_RS00140 ^@ http://purl.uniprot.org/uniprot/A0A386H976 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.|||Single-chain monomer with multiple functions. http://togogenome.org/gene/1604335:DXZ79_RS03585 ^@ http://purl.uniprot.org/uniprot/A0A386HB26 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/1604335:DXZ79_RS17785 ^@ http://purl.uniprot.org/uniprot/A0A386HI69 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/1604335:DXZ79_RS03815 ^@ http://purl.uniprot.org/uniprot/A0A386HAV0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS00370 ^@ http://purl.uniprot.org/uniprot/A0A386H9P0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1604335:DXZ79_RS20545 ^@ http://purl.uniprot.org/uniprot/A0A386HKD1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. http://togogenome.org/gene/1604335:DXZ79_RS07510 ^@ http://purl.uniprot.org/uniprot/A0A386HD54 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS11255 ^@ http://purl.uniprot.org/uniprot/A0A386HEK0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArnE family.|||Cell inner membrane|||Heterodimer of ArnE and ArnF.|||Membrane|||Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane. http://togogenome.org/gene/1604335:DXZ79_RS08630 ^@ http://purl.uniprot.org/uniprot/A0A386HD72 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1604335:DXZ79_RS03845 ^@ http://purl.uniprot.org/uniprot/A0A386HBD4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/1604335:DXZ79_RS02275 ^@ http://purl.uniprot.org/uniprot/A0A386HAF5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-to-5' exoribonuclease specific for small oligoribonucleotides.|||Belongs to the oligoribonuclease family.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS12210 ^@ http://purl.uniprot.org/uniprot/A0A8D4SNI0 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1604335:DXZ79_RS02120 ^@ http://purl.uniprot.org/uniprot/A0A8D4SP43 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.|||Homohexamer; trimer of dimers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS09825 ^@ http://purl.uniprot.org/uniprot/A0A386HED8 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/1604335:DXZ79_RS00580 ^@ http://purl.uniprot.org/uniprot/A0A386HA41 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/1604335:DXZ79_RS17875 ^@ http://purl.uniprot.org/uniprot/A0A386HIN2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS02245 ^@ http://purl.uniprot.org/uniprot/A0A386HAU5 ^@ Cofactor|||Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/1604335:DXZ79_RS20535 ^@ http://purl.uniprot.org/uniprot/A0A386HJJ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS07125 ^@ http://purl.uniprot.org/uniprot/A0A386HD91 ^@ Function|||Similarity ^@ Belongs to the Dus family. DusC subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. http://togogenome.org/gene/1604335:DXZ79_RS17260 ^@ http://purl.uniprot.org/uniprot/A0A386HIC9 ^@ Subunit ^@ Monomer. http://togogenome.org/gene/1604335:DXZ79_RS17915 ^@ http://purl.uniprot.org/uniprot/A0A386HHP1 ^@ Similarity|||Subunit ^@ Belongs to the SIS family. GutQ/KpsF subfamily.|||Homotetramer. http://togogenome.org/gene/1604335:DXZ79_RS09370 ^@ http://purl.uniprot.org/uniprot/A0A386HDV7 ^@ Similarity ^@ Belongs to the UPF0162 family. http://togogenome.org/gene/1604335:DXZ79_RS06365 ^@ http://purl.uniprot.org/uniprot/A0A386HCA0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrcB (TC 9.B.71) family.|||Cell membrane|||Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS12065 ^@ http://purl.uniprot.org/uniprot/A0A8D4N4M0 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS04190 ^@ http://purl.uniprot.org/uniprot/A0A386HBS3 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS05635 ^@ http://purl.uniprot.org/uniprot/A0A386HCM4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS07665 ^@ http://purl.uniprot.org/uniprot/A0A386HDD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS11825 ^@ http://purl.uniprot.org/uniprot/A0A386HF20 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell membrane|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/1604335:DXZ79_RS15100 ^@ http://purl.uniprot.org/uniprot/A0A386HHA1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.|||Bacterial flagellum basal body|||Belongs to the YcgR family.|||Monomer. Interacts with the flagellar basal bodies. http://togogenome.org/gene/1604335:DXZ79_RS20350 ^@ http://purl.uniprot.org/uniprot/A0A386HIW1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/1604335:DXZ79_RS06590 ^@ http://purl.uniprot.org/uniprot/A0A386HD26 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/1604335:DXZ79_RS15275 ^@ http://purl.uniprot.org/uniprot/A0A386HGY7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrF family.|||Binds 1 [2Fe-2S] cluster.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway. http://togogenome.org/gene/1604335:DXZ79_RS17205 ^@ http://purl.uniprot.org/uniprot/A0A386HI65 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS10805 ^@ http://purl.uniprot.org/uniprot/A0A386HF16 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Cell inner membrane|||Membrane|||Zinc transporter. Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake. http://togogenome.org/gene/1604335:DXZ79_RS18200 ^@ http://purl.uniprot.org/uniprot/A0A8D4SS29 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/1604335:DXZ79_RS15345 ^@ http://purl.uniprot.org/uniprot/A0A386HH44 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.|||Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).|||Binds 1 Mg(2+) ion per subunit.|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS18995 ^@ http://purl.uniprot.org/uniprot/A0A386HIT3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1604335:DXZ79_RS13740 ^@ http://purl.uniprot.org/uniprot/A0A386HG95 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS10280 ^@ http://purl.uniprot.org/uniprot/A0A386HDZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS11000 ^@ http://purl.uniprot.org/uniprot/A0A386HF03 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SlyA family.|||Homodimer.|||Transcription regulator that can specifically activate or repress expression of target genes. http://togogenome.org/gene/1604335:DXZ79_RS06575 ^@ http://purl.uniprot.org/uniprot/A0A386HC56 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS08980 ^@ http://purl.uniprot.org/uniprot/A0A8D4SQ81 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/1604335:DXZ79_RS05320 ^@ http://purl.uniprot.org/uniprot/A0A8D4N2X8 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity ^@ Belongs to the globin family. Two-domain flavohemoproteins subfamily.|||Binds 1 FAD per subunit.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.|||Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS06565 ^@ http://purl.uniprot.org/uniprot/A0A386HCN2 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).|||Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS00585 ^@ http://purl.uniprot.org/uniprot/A0A8D4SQS5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsN family.|||Cell inner membrane|||Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.|||Interacts with FtsA via its N-terminal cytoplasmic domain. http://togogenome.org/gene/1604335:DXZ79_RS06580 ^@ http://purl.uniprot.org/uniprot/A0A386HCW6 ^@ Similarity ^@ Belongs to the outer membrane porin (Opr) (TC 1.B.25) family. http://togogenome.org/gene/1604335:DXZ79_RS05335 ^@ http://purl.uniprot.org/uniprot/A0A8D4MY64 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS07390 ^@ http://purl.uniprot.org/uniprot/A0A8D4N048 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/1604335:DXZ79_RS05405 ^@ http://purl.uniprot.org/uniprot/A0A386HCI3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Homohexamer.|||Probably plays an important role in intracellular peptide degradation. http://togogenome.org/gene/1604335:DXZ79_RS16940 ^@ http://purl.uniprot.org/uniprot/A0A386HHD2 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1604335:DXZ79_RS18120 ^@ http://purl.uniprot.org/uniprot/A0A386HIC7 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/1604335:DXZ79_RS01100 ^@ http://purl.uniprot.org/uniprot/A0A386H9W3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS14795 ^@ http://purl.uniprot.org/uniprot/A0A386HG69 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/1604335:DXZ79_RS18180 ^@ http://purl.uniprot.org/uniprot/A0A386HHU3 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1604335:DXZ79_RS08175 ^@ http://purl.uniprot.org/uniprot/A0A8D4MZ04 ^@ Similarity ^@ Belongs to the thioesterase family. http://togogenome.org/gene/1604335:DXZ79_RS02145 ^@ http://purl.uniprot.org/uniprot/A0A386HAJ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS01415 ^@ http://purl.uniprot.org/uniprot/A0A386HAH4 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/1604335:DXZ79_RS18355 ^@ http://purl.uniprot.org/uniprot/A0A386HI95 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily.|||Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(palmitoleoyl)-lipid IV(A).|||Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS09255 ^@ http://purl.uniprot.org/uniprot/A0A386HDU5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family.|||Binds 1 zinc or iron ion per subunit.|||Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS02430 ^@ http://purl.uniprot.org/uniprot/A0A386HAU4 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1604335:DXZ79_RS14900 ^@ http://purl.uniprot.org/uniprot/A0A386HG90 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1604335:DXZ79_RS16330 ^@ http://purl.uniprot.org/uniprot/A0A386HHG6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS08510 ^@ http://purl.uniprot.org/uniprot/A0A386HDH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS10855 ^@ http://purl.uniprot.org/uniprot/A0A386HF26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0283 family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS11680 ^@ http://purl.uniprot.org/uniprot/A0A8D4N1F7 ^@ Function|||Similarity ^@ Belongs to the class-C beta-lactamase family.|||This protein is a serine beta-lactamase with a substrate specificity for cephalosporins. http://togogenome.org/gene/1604335:DXZ79_RS03880 ^@ http://purl.uniprot.org/uniprot/A0A386HBD5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DNA gyrase inhibitor YacG family.|||Binds 1 zinc ion.|||Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.|||Interacts with GyrB. http://togogenome.org/gene/1604335:DXZ79_RS04145 ^@ http://purl.uniprot.org/uniprot/A0A386HB18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS01220 ^@ http://purl.uniprot.org/uniprot/A0A386HAE2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring. http://togogenome.org/gene/1604335:DXZ79_RS17975 ^@ http://purl.uniprot.org/uniprot/A0A386HHQ0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the PyrI family.|||Binds 1 zinc ion per subunit.|||Contains catalytic and regulatory chains.|||Involved in allosteric regulation of aspartate carbamoyltransferase. http://togogenome.org/gene/1604335:DXZ79_RS01015 ^@ http://purl.uniprot.org/uniprot/A0A386H9I4 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Involved in a late step of protoheme IX synthesis.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS14955 ^@ http://purl.uniprot.org/uniprot/A0A386HGA0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane|||Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).|||The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. http://togogenome.org/gene/1604335:DXZ79_RS13840 ^@ http://purl.uniprot.org/uniprot/A0A386HG86 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/1604335:DXZ79_RS17245 ^@ http://purl.uniprot.org/uniprot/A0A386HHE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS00640 ^@ http://purl.uniprot.org/uniprot/A0A386H9N7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS12030 ^@ http://purl.uniprot.org/uniprot/A0A386HFK4 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1604335:DXZ79_RS12420 ^@ http://purl.uniprot.org/uniprot/A0A386HFI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS17670 ^@ http://purl.uniprot.org/uniprot/A0A386HIC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS00915 ^@ http://purl.uniprot.org/uniprot/A0A386HA98 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure. http://togogenome.org/gene/1604335:DXZ79_RS19285 ^@ http://purl.uniprot.org/uniprot/A0A386HIU6 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1604335:DXZ79_RS13145 ^@ http://purl.uniprot.org/uniprot/A0A386HFQ8 ^@ Similarity ^@ Belongs to the elongation factor P family. http://togogenome.org/gene/1604335:DXZ79_RS19900 ^@ http://purl.uniprot.org/uniprot/A0A386HIL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS11280 ^@ http://purl.uniprot.org/uniprot/A0A386HF00 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.|||Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS04965 ^@ http://purl.uniprot.org/uniprot/A0A386HBW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS17380 ^@ http://purl.uniprot.org/uniprot/A0A386HHT1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS04330 ^@ http://purl.uniprot.org/uniprot/A0A386HB43 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs. http://togogenome.org/gene/1604335:DXZ79_RS08325 ^@ http://purl.uniprot.org/uniprot/A0A386HDY2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1604335:DXZ79_RS04445 ^@ http://purl.uniprot.org/uniprot/A0A386HB78 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1604335:DXZ79_RS11195 ^@ http://purl.uniprot.org/uniprot/A0A8D4N4A6 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/1604335:DXZ79_RS05885 ^@ http://purl.uniprot.org/uniprot/A0A386HC83 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the aerobic coproporphyrinogen-III oxidase family.|||Cytoplasm|||Homodimer.|||Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. http://togogenome.org/gene/1604335:DXZ79_RS02255 ^@ http://purl.uniprot.org/uniprot/A0A386HAR0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.|||Homodimer.|||With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P. http://togogenome.org/gene/1604335:DXZ79_RS18475 ^@ http://purl.uniprot.org/uniprot/A0A386HJC7 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPAT/DAPAT family.|||Cell membrane|||The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. http://togogenome.org/gene/1604335:DXZ79_RS07150 ^@ http://purl.uniprot.org/uniprot/A0A386HD49 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinone-dependent D-lactate dehydrogenase family.|||Catalyzes the oxidation of D-lactate to pyruvate.|||Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS10830 ^@ http://purl.uniprot.org/uniprot/A0A386HEX6 ^@ Cofactor|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/1604335:DXZ79_RS06335 ^@ http://purl.uniprot.org/uniprot/A0A386HC44 ^@ Function|||Similarity ^@ Belongs to the GlgS family.|||Major determinant of cell surface composition. Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides. http://togogenome.org/gene/1604335:DXZ79_RS01155 ^@ http://purl.uniprot.org/uniprot/A0A8D4MZ35 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.|||Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS11330 ^@ http://purl.uniprot.org/uniprot/A0A386HFD2 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1604335:DXZ79_RS06405 ^@ http://purl.uniprot.org/uniprot/A0A386HCM3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/1604335:DXZ79_RS19030 ^@ http://purl.uniprot.org/uniprot/A0A386HIX6 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||Methylated by PrmB.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/1604335:DXZ79_RS20385 ^@ http://purl.uniprot.org/uniprot/A0A386HJD4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TER reductase family.|||Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS16280 ^@ http://purl.uniprot.org/uniprot/A0A386HI94 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/1604335:DXZ79_RS13895 ^@ http://purl.uniprot.org/uniprot/A0A8D4SRD4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 24 family. http://togogenome.org/gene/1604335:DXZ79_RS10155 ^@ http://purl.uniprot.org/uniprot/A0A386HEX8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS20550 ^@ http://purl.uniprot.org/uniprot/A0A386HJG2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/1604335:DXZ79_RS01395 ^@ http://purl.uniprot.org/uniprot/A0A386HA07 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1604335:DXZ79_RS18340 ^@ http://purl.uniprot.org/uniprot/A0A8D4SPK0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS13100 ^@ http://purl.uniprot.org/uniprot/A0A8D4N6A3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS01705 ^@ http://purl.uniprot.org/uniprot/A0A386H9R9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS11125 ^@ http://purl.uniprot.org/uniprot/A0A386HEP1 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1604335:DXZ79_RS05870 ^@ http://purl.uniprot.org/uniprot/A0A386HC34 ^@ Similarity ^@ In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the malic enzymes family. http://togogenome.org/gene/1604335:DXZ79_RS17645 ^@ http://purl.uniprot.org/uniprot/A0A386HHX6 ^@ Similarity ^@ Belongs to the mannitol dehydrogenase family. UxaB subfamily. http://togogenome.org/gene/1604335:DXZ79_RS06990 ^@ http://purl.uniprot.org/uniprot/A0A386HCW3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.|||Belongs to the AcrZ family.|||Cell membrane|||Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB. http://togogenome.org/gene/1604335:DXZ79_RS06280 ^@ http://purl.uniprot.org/uniprot/A0A386HC08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0312 family. Type 1 subfamily.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS03250 ^@ http://purl.uniprot.org/uniprot/A0A386HBA1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS09205 ^@ http://purl.uniprot.org/uniprot/A0A386HDT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS20290 ^@ http://purl.uniprot.org/uniprot/A0A386HJB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS02885 ^@ http://purl.uniprot.org/uniprot/A0A386HAK5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptF/LptG family.|||Cell inner membrane|||Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).|||Membrane|||Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. http://togogenome.org/gene/1604335:DXZ79_RS17310 ^@ http://purl.uniprot.org/uniprot/A0A386HID6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase class-III family.|||Binds 2 Fe(2+) ions per subunit.|||Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. http://togogenome.org/gene/1604335:DXZ79_RS12615 ^@ http://purl.uniprot.org/uniprot/A0A386HF30 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS09380 ^@ http://purl.uniprot.org/uniprot/A0A8D4N501 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS12775 ^@ http://purl.uniprot.org/uniprot/A0A386HFZ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LolA family.|||Monomer.|||Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS18955 ^@ http://purl.uniprot.org/uniprot/A0A386HJK1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1604335:DXZ79_RS03620 ^@ http://purl.uniprot.org/uniprot/A0A386HAW7 ^@ Function|||Similarity ^@ Belongs to the Ap4A hydrolase family.|||Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP. http://togogenome.org/gene/1604335:DXZ79_RS04600 ^@ http://purl.uniprot.org/uniprot/A0A386HBR0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS14800 ^@ http://purl.uniprot.org/uniprot/A0A386HGU5 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1604335:DXZ79_RS16845 ^@ http://purl.uniprot.org/uniprot/A0A386HHP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS00535 ^@ http://purl.uniprot.org/uniprot/A0A386H9S1 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/1604335:DXZ79_RS02515 ^@ http://purl.uniprot.org/uniprot/A0A386HAN9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/1604335:DXZ79_RS13240 ^@ http://purl.uniprot.org/uniprot/A0A386HGC9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/1604335:DXZ79_RS14675 ^@ http://purl.uniprot.org/uniprot/A0A386HG53 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/1604335:DXZ79_RS00355 ^@ http://purl.uniprot.org/uniprot/A0A386H9R4 ^@ Similarity ^@ Belongs to the UPF0758 family. YicR subfamily. http://togogenome.org/gene/1604335:DXZ79_RS09415 ^@ http://purl.uniprot.org/uniprot/A0A386HEA8 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the PHP family.|||Binds 3 Zn(2+) ions per subunit.|||Homotrimer. http://togogenome.org/gene/1604335:DXZ79_RS04610 ^@ http://purl.uniprot.org/uniprot/A0A386HB87 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS06415 ^@ http://purl.uniprot.org/uniprot/A0A386HCB1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/1604335:DXZ79_RS03850 ^@ http://purl.uniprot.org/uniprot/A0A386HBL9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/1604335:DXZ79_RS09960 ^@ http://purl.uniprot.org/uniprot/A0A386HEG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS02625 ^@ http://purl.uniprot.org/uniprot/A0A386HAM4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/1604335:DXZ79_RS11540 ^@ http://purl.uniprot.org/uniprot/A0A386HFT7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS03380 ^@ http://purl.uniprot.org/uniprot/A0A8D4MZH3 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/1604335:DXZ79_RS02525 ^@ http://purl.uniprot.org/uniprot/A0A386HA68 ^@ Similarity ^@ Belongs to the ner transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS09030 ^@ http://purl.uniprot.org/uniprot/A0A8D4SRR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:citrate (SCF) symporter family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS09575 ^@ http://purl.uniprot.org/uniprot/A0A386HE65 ^@ Similarity|||Subunit ^@ Belongs to the KHG/KDPG aldolase family.|||Homotrimer. http://togogenome.org/gene/1604335:DXZ79_RS05455 ^@ http://purl.uniprot.org/uniprot/A0A386HCC6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/1604335:DXZ79_RS09440 ^@ http://purl.uniprot.org/uniprot/A0A386HE71 ^@ Similarity ^@ Belongs to the UPF0502 family. http://togogenome.org/gene/1604335:DXZ79_RS05945 ^@ http://purl.uniprot.org/uniprot/A0A386HCD7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/1604335:DXZ79_RS05155 ^@ http://purl.uniprot.org/uniprot/A0A386HBU6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DEAD box helicase family. SrmB subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.|||Interacts with the 50S ribosomal subunit. http://togogenome.org/gene/1604335:DXZ79_RS16795 ^@ http://purl.uniprot.org/uniprot/A0A386HIH5 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/1604335:DXZ79_RS08555 ^@ http://purl.uniprot.org/uniprot/A0A386HDI3 ^@ Function ^@ Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. http://togogenome.org/gene/1604335:DXZ79_RS03570 ^@ http://purl.uniprot.org/uniprot/A0A386HAV4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS09785 ^@ http://purl.uniprot.org/uniprot/A0A386HEH7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the selenophosphate synthase 1 family. Class I subfamily.|||Binds 1 Mg(2+) ion per monomer.|||Homodimer.|||Synthesizes selenophosphate from selenide and ATP. http://togogenome.org/gene/1604335:DXZ79_RS11285 ^@ http://purl.uniprot.org/uniprot/A0A386HFI3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.|||Cell membrane|||Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF). http://togogenome.org/gene/1604335:DXZ79_RS19105 ^@ http://purl.uniprot.org/uniprot/A0A386HIS5 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1604335:DXZ79_RS09505 ^@ http://purl.uniprot.org/uniprot/A0A386HE78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS00830 ^@ http://purl.uniprot.org/uniprot/A0A386H9Y7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS11270 ^@ http://purl.uniprot.org/uniprot/A0A386HFB8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.|||Homohexamer, formed by a dimer of trimers.|||In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.|||In the N-terminal section; belongs to the Fmt family. UDP-L-Ara4N formyltransferase subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS13550 ^@ http://purl.uniprot.org/uniprot/A0A386HGW3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1604335:DXZ79_RS08845 ^@ http://purl.uniprot.org/uniprot/A0A386HDW0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DyP-type peroxidase family. EfeB subfamily.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.|||Homodimer. Part of a ferrous iron transporter composed of EfeU, EfeO and EfeB.|||Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS19005 ^@ http://purl.uniprot.org/uniprot/A0A386HJK9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1604335:DXZ79_RS14150 ^@ http://purl.uniprot.org/uniprot/A0A386HGN0 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1604335:DXZ79_RS03415 ^@ http://purl.uniprot.org/uniprot/A0A386HAZ6 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/1604335:DXZ79_RS02370 ^@ http://purl.uniprot.org/uniprot/A0A386HAN5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.|||Cytoplasm|||Homodimer.|||Specifically methylates the ribose of guanosine 2251 in 23S rRNA. http://togogenome.org/gene/1604335:DXZ79_RS10275 ^@ http://purl.uniprot.org/uniprot/A0A8D4N244 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS15690 ^@ http://purl.uniprot.org/uniprot/A0A386HHB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0382 family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS00390 ^@ http://purl.uniprot.org/uniprot/A0A8D4SNU7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Cell inner membrane|||Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. http://togogenome.org/gene/1604335:DXZ79_RS08835 ^@ http://purl.uniprot.org/uniprot/A0A386HE81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS05210 ^@ http://purl.uniprot.org/uniprot/A0A386HBV3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS04135 ^@ http://purl.uniprot.org/uniprot/A0A386HBC3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HesB/IscA family.|||Binds 1 iron-sulfur cluster per subunit.|||Homodimer.|||Required for insertion of 4Fe-4S clusters for at least IspG. http://togogenome.org/gene/1604335:DXZ79_RS02785 ^@ http://purl.uniprot.org/uniprot/A0A386HAV7 ^@ Function|||Similarity ^@ Belongs to the PhnJ family.|||Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. http://togogenome.org/gene/1604335:DXZ79_RS06425 ^@ http://purl.uniprot.org/uniprot/A0A386HCX0 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/1604335:DXZ79_RS20500 ^@ http://purl.uniprot.org/uniprot/A0A386HJF2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1604335:DXZ79_RS11420 ^@ http://purl.uniprot.org/uniprot/A0A386HF22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS07640 ^@ http://purl.uniprot.org/uniprot/A0A386HDJ6 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/1604335:DXZ79_RS00615 ^@ http://purl.uniprot.org/uniprot/A0A386H9V9 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1604335:DXZ79_RS02555 ^@ http://purl.uniprot.org/uniprot/A0A386HB29 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS02400 ^@ http://purl.uniprot.org/uniprot/A0A386HAH9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/1604335:DXZ79_RS13180 ^@ http://purl.uniprot.org/uniprot/A0A386HG61 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1604335:DXZ79_RS18195 ^@ http://purl.uniprot.org/uniprot/A0A8D4SRQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS06750 ^@ http://purl.uniprot.org/uniprot/A0A386HD55 ^@ Function|||Similarity ^@ Belongs to the alpha-ketoglutarate dehydrogenase family.|||E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/1604335:DXZ79_RS05030 ^@ http://purl.uniprot.org/uniprot/A0A386HBY1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HdeB family.|||Periplasm|||Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins. http://togogenome.org/gene/1604335:DXZ79_RS11755 ^@ http://purl.uniprot.org/uniprot/A0A8D4N3Q2 ^@ Function|||Similarity ^@ Belongs to the N(4)-acetylcytidine amidohydrolase family.|||Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C). http://togogenome.org/gene/1604335:DXZ79_RS14670 ^@ http://purl.uniprot.org/uniprot/A0A386HGQ8 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1604335:DXZ79_RS00340 ^@ http://purl.uniprot.org/uniprot/A0A386H9T4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the nucleoid occlusion factor SlmA family.|||Homodimer. Interacts with FtsZ.|||Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.|||nucleoid http://togogenome.org/gene/1604335:DXZ79_RS01270 ^@ http://purl.uniprot.org/uniprot/A0A386H9K0 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1604335:DXZ79_RS11050 ^@ http://purl.uniprot.org/uniprot/A0A8E4BMU2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase T family.|||Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.|||Homodimer.|||Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. http://togogenome.org/gene/1604335:DXZ79_RS06600 ^@ http://purl.uniprot.org/uniprot/A0A386HCL5 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/1604335:DXZ79_RS17090 ^@ http://purl.uniprot.org/uniprot/A0A386HI02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS07020 ^@ http://purl.uniprot.org/uniprot/A0A386HCV7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.|||Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS00020 ^@ http://purl.uniprot.org/uniprot/A0A386H9K7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS12715 ^@ http://purl.uniprot.org/uniprot/A0A386HF75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS05980 ^@ http://purl.uniprot.org/uniprot/A0A386HCS6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/1604335:DXZ79_RS16365 ^@ http://purl.uniprot.org/uniprot/A0A8D4N2W8 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/1604335:DXZ79_RS09670 ^@ http://purl.uniprot.org/uniprot/A0A386HEB3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DsbB family.|||Cell inner membrane|||Cell membrane|||Membrane|||Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein. http://togogenome.org/gene/1604335:DXZ79_RS13065 ^@ http://purl.uniprot.org/uniprot/A0A386HG99 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/1604335:DXZ79_RS13780 ^@ http://purl.uniprot.org/uniprot/A0A386HH03 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1604335:DXZ79_RS05735 ^@ http://purl.uniprot.org/uniprot/A0A386HBW3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamC family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/1604335:DXZ79_RS11935 ^@ http://purl.uniprot.org/uniprot/A0A386HF39 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS20450 ^@ http://purl.uniprot.org/uniprot/A0A386HJE6 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1604335:DXZ79_RS10080 ^@ http://purl.uniprot.org/uniprot/A0A8D4SQE8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Cob(I)alamin adenosyltransferase family.|||Cytoplasm|||Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. http://togogenome.org/gene/1604335:DXZ79_RS00250 ^@ http://purl.uniprot.org/uniprot/A0A386H955 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/1604335:DXZ79_RS05435 ^@ http://purl.uniprot.org/uniprot/A0A386HBZ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/1604335:DXZ79_RS02330 ^@ http://purl.uniprot.org/uniprot/A0A386HA94 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/1604335:DXZ79_RS02340 ^@ http://purl.uniprot.org/uniprot/A0A386HAZ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the band 7/mec-2 family. HflK subfamily.|||HflC and HflK could encode or regulate a protease.|||HflC and HflK may interact to form a multimeric complex.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS11770 ^@ http://purl.uniprot.org/uniprot/A0A8D4N4Y3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Homodimer.|||Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. http://togogenome.org/gene/1604335:DXZ79_RS03645 ^@ http://purl.uniprot.org/uniprot/A0A8D4MZY7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptD family.|||Cell outer membrane|||Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. http://togogenome.org/gene/1604335:DXZ79_RS17330 ^@ http://purl.uniprot.org/uniprot/A0A8E4BMJ1 ^@ Similarity ^@ Belongs to the UPF0441 family. http://togogenome.org/gene/1604335:DXZ79_RS15010 ^@ http://purl.uniprot.org/uniprot/A0A386HGT9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS09360 ^@ http://purl.uniprot.org/uniprot/A0A386HE25 ^@ Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/1604335:DXZ79_RS11490 ^@ http://purl.uniprot.org/uniprot/A0A386HEV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS01515 ^@ http://purl.uniprot.org/uniprot/A0A386HAB4 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS06735 ^@ http://purl.uniprot.org/uniprot/A0A386HC87 ^@ Cofactor|||Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/1604335:DXZ79_RS10475 ^@ http://purl.uniprot.org/uniprot/A0A386HF33 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS03835 ^@ http://purl.uniprot.org/uniprot/A0A8D4N2N9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS12780 ^@ http://purl.uniprot.org/uniprot/A0A386HG48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS00970 ^@ http://purl.uniprot.org/uniprot/A0A386HA29 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 56 family.|||Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.|||Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS19275 ^@ http://purl.uniprot.org/uniprot/A0A386HJC2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.|||Monomer.|||Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. http://togogenome.org/gene/1604335:DXZ79_RS19655 ^@ http://purl.uniprot.org/uniprot/A0A386HII1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the periplasmic pilus chaperone family.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS09285 ^@ http://purl.uniprot.org/uniprot/A0A386HE36 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/1604335:DXZ79_RS03920 ^@ http://purl.uniprot.org/uniprot/A0A386HBC8 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/1604335:DXZ79_RS02125 ^@ http://purl.uniprot.org/uniprot/A0A386HAH8 ^@ Function|||Similarity ^@ Belongs to the HIBADH-related family. 2-hydroxy-3-oxopropionate reductase subfamily.|||Catalyzes the reduction of tatronate semialdehyde to D-glycerate. http://togogenome.org/gene/1604335:DXZ79_RS12650 ^@ http://purl.uniprot.org/uniprot/A0A386HFH2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MukF family.|||Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.|||Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.|||nucleoid http://togogenome.org/gene/1604335:DXZ79_RS19070 ^@ http://purl.uniprot.org/uniprot/A0A386HJ03 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1604335:DXZ79_RS18350 ^@ http://purl.uniprot.org/uniprot/A0A386HIX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS03605 ^@ http://purl.uniprot.org/uniprot/A0A386HBF9 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/1604335:DXZ79_RS03670 ^@ http://purl.uniprot.org/uniprot/A0A386HBG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS04045 ^@ http://purl.uniprot.org/uniprot/A0A386HAZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS00255 ^@ http://purl.uniprot.org/uniprot/A0A8D4N2W9 ^@ Caution|||Function|||Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS18800 ^@ http://purl.uniprot.org/uniprot/A0A386HIZ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS10135 ^@ http://purl.uniprot.org/uniprot/A0A386HEK5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LapA family.|||Cell inner membrane|||Involved in the assembly of lipopolysaccharide (LPS).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS05730 ^@ http://purl.uniprot.org/uniprot/A0A8E4DFG1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1604335:DXZ79_RS19205 ^@ http://purl.uniprot.org/uniprot/A0A386HIA5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||Involved in both the arginine and lysine biosynthetic pathways.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS09515 ^@ http://purl.uniprot.org/uniprot/A0A386HEC9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/1604335:DXZ79_RS04620 ^@ http://purl.uniprot.org/uniprot/A0A386HBR9 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1604335:DXZ79_RS11095 ^@ http://purl.uniprot.org/uniprot/A0A386HEW8 ^@ Function ^@ Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil. http://togogenome.org/gene/1604335:DXZ79_RS00935 ^@ http://purl.uniprot.org/uniprot/A0A386H9F0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family.|||Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS18860 ^@ http://purl.uniprot.org/uniprot/A0A386HIW3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1604335:DXZ79_RS11315 ^@ http://purl.uniprot.org/uniprot/A0A386HF52 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1604335:DXZ79_RS10395 ^@ http://purl.uniprot.org/uniprot/A0A386HEN2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS03385 ^@ http://purl.uniprot.org/uniprot/A0A386HBB9 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/1604335:DXZ79_RS01655 ^@ http://purl.uniprot.org/uniprot/A0A386H9R0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS05835 ^@ http://purl.uniprot.org/uniprot/A0A386HCC1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NapD family.|||Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.|||Cytoplasm|||Interacts with the cytoplasmic NapA precursor. http://togogenome.org/gene/1604335:DXZ79_RS07305 ^@ http://purl.uniprot.org/uniprot/A0A386HCX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS08530 ^@ http://purl.uniprot.org/uniprot/A0A386HD57 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/1604335:DXZ79_RS06970 ^@ http://purl.uniprot.org/uniprot/A0A386HCU2 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS18630 ^@ http://purl.uniprot.org/uniprot/A0A386HIJ4 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/1604335:DXZ79_RS04910 ^@ http://purl.uniprot.org/uniprot/A0A386HC40 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Asr family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Periplasm|||Proteolytic processing gives rise to the active protein.|||Required for growth and/or survival at acidic conditions. http://togogenome.org/gene/1604335:DXZ79_RS12925 ^@ http://purl.uniprot.org/uniprot/A0A386HFB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 3 family.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS04870 ^@ http://purl.uniprot.org/uniprot/A0A386HBV0 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1604335:DXZ79_RS08610 ^@ http://purl.uniprot.org/uniprot/A0A386HE35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/1604335:DXZ79_RS01030 ^@ http://purl.uniprot.org/uniprot/A0A386HA47 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/1604335:DXZ79_RS04760 ^@ http://purl.uniprot.org/uniprot/A0A386HBJ2 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1604335:DXZ79_RS20345 ^@ http://purl.uniprot.org/uniprot/A0A386HJK7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/1604335:DXZ79_RS04730 ^@ http://purl.uniprot.org/uniprot/A0A8D4N298 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS18480 ^@ http://purl.uniprot.org/uniprot/A0A386HKA9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family.|||Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.|||Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS18850 ^@ http://purl.uniprot.org/uniprot/A0A386HJH7 ^@ Similarity ^@ Belongs to the Smg family. http://togogenome.org/gene/1604335:DXZ79_RS10125 ^@ http://purl.uniprot.org/uniprot/A0A8E4BMC7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase II family.|||Binds 1 zinc ion per subunit.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS10455 ^@ http://purl.uniprot.org/uniprot/A0A386HER4 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/1604335:DXZ79_RS05575 ^@ http://purl.uniprot.org/uniprot/A0A8E4BJN6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.|||Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.|||Cytoplasm|||Probably phosphorylates lipids; the in vivo substrate is unknown. http://togogenome.org/gene/1604335:DXZ79_RS03780 ^@ http://purl.uniprot.org/uniprot/A0A386HB05 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.|||nucleoid http://togogenome.org/gene/1604335:DXZ79_RS05005 ^@ http://purl.uniprot.org/uniprot/A0A386HCA3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreF family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/1604335:DXZ79_RS20280 ^@ http://purl.uniprot.org/uniprot/A0A386HJB5 ^@ Cofactor ^@ Binds 1 Ca(2+) ion per subunit. http://togogenome.org/gene/1604335:DXZ79_RS18110 ^@ http://purl.uniprot.org/uniprot/A0A386HIB6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS18750 ^@ http://purl.uniprot.org/uniprot/A0A386HIL4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1604335:DXZ79_RS09320 ^@ http://purl.uniprot.org/uniprot/A0A386HE48 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/1604335:DXZ79_RS00485 ^@ http://purl.uniprot.org/uniprot/A0A386H992 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpxP/Spy family.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS05990 ^@ http://purl.uniprot.org/uniprot/A0A386HCC4 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1604335:DXZ79_RS02730 ^@ http://purl.uniprot.org/uniprot/A0A386HB52 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS15485 ^@ http://purl.uniprot.org/uniprot/A0A386HH73 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/1604335:DXZ79_RS17000 ^@ http://purl.uniprot.org/uniprot/A0A8D4N333 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/1604335:DXZ79_RS15270 ^@ http://purl.uniprot.org/uniprot/A0A386HHQ6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ApbE family.|||Cell inner membrane|||Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.|||Magnesium. Can also use manganese. http://togogenome.org/gene/1604335:DXZ79_RS08685 ^@ http://purl.uniprot.org/uniprot/A0A386HD86 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliN/MopA/SpaO family.|||Cell membrane|||FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS11445 ^@ http://purl.uniprot.org/uniprot/A0A386HEH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS08690 ^@ http://purl.uniprot.org/uniprot/A0A386HD81 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Cell inner membrane|||FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS09065 ^@ http://purl.uniprot.org/uniprot/A0A386HDY9 ^@ Caution|||Similarity|||Subunit ^@ Belongs to the glutaminase family.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS02470 ^@ http://purl.uniprot.org/uniprot/A0A386HA60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TamA family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS04690 ^@ http://purl.uniprot.org/uniprot/A0A386HC00 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/1604335:DXZ79_RS18740 ^@ http://purl.uniprot.org/uniprot/A0A386HJH1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS12810 ^@ http://purl.uniprot.org/uniprot/A0A386HF70 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1604335:DXZ79_RS05195 ^@ http://purl.uniprot.org/uniprot/A0A386HBR3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/1604335:DXZ79_RS03530 ^@ http://purl.uniprot.org/uniprot/A0A386HB17 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS18150 ^@ http://purl.uniprot.org/uniprot/A0A386HIS8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/1604335:DXZ79_RS16210 ^@ http://purl.uniprot.org/uniprot/A0A386HHN0 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/1604335:DXZ79_RS11850 ^@ http://purl.uniprot.org/uniprot/A0A386HFH6 ^@ Function|||Similarity ^@ Belongs to the transpeptidase family. FtsI subfamily.|||Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. http://togogenome.org/gene/1604335:DXZ79_RS06390 ^@ http://purl.uniprot.org/uniprot/A0A386HC53 ^@ Similarity ^@ Belongs to the UPF0250 family. http://togogenome.org/gene/1604335:DXZ79_RS18535 ^@ http://purl.uniprot.org/uniprot/A0A386HII5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS10335 ^@ http://purl.uniprot.org/uniprot/A0A386HDZ9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. http://togogenome.org/gene/1604335:DXZ79_RS08660 ^@ http://purl.uniprot.org/uniprot/A0A8E4BMB4 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Secreted http://togogenome.org/gene/1604335:DXZ79_RS19180 ^@ http://purl.uniprot.org/uniprot/A0A386HIT0 ^@ Similarity ^@ Belongs to the phosphoribulokinase family. http://togogenome.org/gene/1604335:DXZ79_RS15145 ^@ http://purl.uniprot.org/uniprot/A0A386HH53 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Crl family.|||Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS01105 ^@ http://purl.uniprot.org/uniprot/A0A386HA10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EamA transporter family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS14510 ^@ http://purl.uniprot.org/uniprot/A0A386HGM8 ^@ Similarity ^@ Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. http://togogenome.org/gene/1604335:DXZ79_RS13495 ^@ http://purl.uniprot.org/uniprot/A0A386HG06 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1604335:DXZ79_RS10460 ^@ http://purl.uniprot.org/uniprot/A0A386HEV0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArsB family.|||Cell membrane|||Involved in arsenical resistance. Thought to form the channel of an arsenite pump.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS14055 ^@ http://purl.uniprot.org/uniprot/A0A386HGF4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmE/CycJ family.|||Cell membrane|||Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. http://togogenome.org/gene/1604335:DXZ79_RS20090 ^@ http://purl.uniprot.org/uniprot/A0A386HJF7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1604335:DXZ79_RS10880 ^@ http://purl.uniprot.org/uniprot/A0A386HEJ9 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/1604335:DXZ79_RS18450 ^@ http://purl.uniprot.org/uniprot/A0A386HIT7 ^@ Function|||Similarity ^@ Belongs to the Dus family. DusA subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs. http://togogenome.org/gene/1604335:DXZ79_RS15035 ^@ http://purl.uniprot.org/uniprot/A0A8D4N2H0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/1604335:DXZ79_RS06720 ^@ http://purl.uniprot.org/uniprot/A0A386HCM0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase C15 family.|||Cytoplasm|||Homotetramer.|||Removes 5-oxoproline from various penultimate amino acid residues except L-proline. http://togogenome.org/gene/1604335:DXZ79_RS13190 ^@ http://purl.uniprot.org/uniprot/A0A8D4N5J8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS02265 ^@ http://purl.uniprot.org/uniprot/A0A386HAM1 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase. http://togogenome.org/gene/1604335:DXZ79_RS13085 ^@ http://purl.uniprot.org/uniprot/A0A8D4N1V9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS05010 ^@ http://purl.uniprot.org/uniprot/A0A386HBN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.|||Cytoplasm|||Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.|||Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/1604335:DXZ79_RS06500 ^@ http://purl.uniprot.org/uniprot/A0A386HCV6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS05170 ^@ http://purl.uniprot.org/uniprot/A0A386HBL1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1604335:DXZ79_RS15280 ^@ http://purl.uniprot.org/uniprot/A0A386HH33 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||Membrane|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/1604335:DXZ79_RS05250 ^@ http://purl.uniprot.org/uniprot/A0A8D4MY54 ^@ Similarity ^@ Belongs to the ner transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS17265 ^@ http://purl.uniprot.org/uniprot/A0A386HHR6 ^@ Cofactor|||Similarity ^@ Belongs to the UPF0313 family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1604335:DXZ79_RS03900 ^@ http://purl.uniprot.org/uniprot/A0A386HBE3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.|||Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.|||Homotetramer. http://togogenome.org/gene/1604335:DXZ79_RS04170 ^@ http://purl.uniprot.org/uniprot/A0A386HBQ0 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS08080 ^@ http://purl.uniprot.org/uniprot/A0A8D4N4K7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS09590 ^@ http://purl.uniprot.org/uniprot/A0A386HE97 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1604335:DXZ79_RS15290 ^@ http://purl.uniprot.org/uniprot/A0A386HGG0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrC family.|||Cell membrane|||Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. http://togogenome.org/gene/1604335:DXZ79_RS11245 ^@ http://purl.uniprot.org/uniprot/A0A386HF46 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1604335:DXZ79_RS13040 ^@ http://purl.uniprot.org/uniprot/A0A386HFA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS16830 ^@ http://purl.uniprot.org/uniprot/A0A8D4ST93 ^@ Similarity|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.|||Heterodimer of a large and a small subunit. http://togogenome.org/gene/1604335:DXZ79_RS20470 ^@ http://purl.uniprot.org/uniprot/A0A386HJN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS04695 ^@ http://purl.uniprot.org/uniprot/A0A386HBS9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/1604335:DXZ79_RS12225 ^@ http://purl.uniprot.org/uniprot/A0A386HEW1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/1604335:DXZ79_RS13505 ^@ http://purl.uniprot.org/uniprot/A0A8D4SSS3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1604335:DXZ79_RS00405 ^@ http://purl.uniprot.org/uniprot/A0A386H9V7 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.|||Binds 1 NADP(+) per subunit.|||Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.|||Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.|||Homopentamer. http://togogenome.org/gene/1604335:DXZ79_RS13140 ^@ http://purl.uniprot.org/uniprot/A0A386HGP7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.|||Cell inner membrane|||Involved in transporting aromatic amino acids across the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS05470 ^@ http://purl.uniprot.org/uniprot/A0A386HBX0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamB family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/1604335:DXZ79_RS02650 ^@ http://purl.uniprot.org/uniprot/A0A386HAS8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/1604335:DXZ79_RS05460 ^@ http://purl.uniprot.org/uniprot/A0A386HC58 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS03080 ^@ http://purl.uniprot.org/uniprot/A0A386HB68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TPS (TC 1.B.20) family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS10665 ^@ http://purl.uniprot.org/uniprot/A0A386HEG2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Heterodimer of an alpha and a beta chain.|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/1604335:DXZ79_RS12725 ^@ http://purl.uniprot.org/uniprot/A0A386HFY5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS03165 ^@ http://purl.uniprot.org/uniprot/A0A8D4SM00 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS00530 ^@ http://purl.uniprot.org/uniprot/A0A8E4DFF2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS15855 ^@ http://purl.uniprot.org/uniprot/A0A8D4N2R0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS07070 ^@ http://purl.uniprot.org/uniprot/A0A386HD74 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/1604335:DXZ79_RS04770 ^@ http://purl.uniprot.org/uniprot/A0A386HC21 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/1604335:DXZ79_RS13585 ^@ http://purl.uniprot.org/uniprot/A0A386HG82 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1604335:DXZ79_RS05740 ^@ http://purl.uniprot.org/uniprot/A0A386HBS7 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/1604335:DXZ79_RS17840 ^@ http://purl.uniprot.org/uniprot/A0A386HI79 ^@ Similarity ^@ Belongs to the GST superfamily. HSP26 family. http://togogenome.org/gene/1604335:DXZ79_RS20155 ^@ http://purl.uniprot.org/uniprot/A0A386HJS8 ^@ Cofactor|||Function ^@ Binds 4 [4Fe-4S] clusters per subunit.|||The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. http://togogenome.org/gene/1604335:DXZ79_RS02235 ^@ http://purl.uniprot.org/uniprot/A0A386HA02 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FrdD family.|||Cell membrane|||Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).|||Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones. http://togogenome.org/gene/1604335:DXZ79_RS13370 ^@ http://purl.uniprot.org/uniprot/A0A386HGF2 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the RcsB family.|||Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.|||Interacts with RcsD.|||Phosphorylated and activated by RcsD. http://togogenome.org/gene/1604335:DXZ79_RS03465 ^@ http://purl.uniprot.org/uniprot/A0A386HBF7 ^@ Similarity|||Subunit ^@ Homotetramer.|||In the C-terminal section; belongs to the homoserine dehydrogenase family.|||In the N-terminal section; belongs to the aspartokinase family. http://togogenome.org/gene/1604335:DXZ79_RS12100 ^@ http://purl.uniprot.org/uniprot/A0A8D4N6S2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS09225 ^@ http://purl.uniprot.org/uniprot/A0A386HDG5 ^@ Function|||Similarity ^@ Belongs to the arginine N-succinyltransferase family.|||Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine. http://togogenome.org/gene/1604335:DXZ79_RS05920 ^@ http://purl.uniprot.org/uniprot/A0A386HCR7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ROK (NagC/XylR) family. NanK subfamily.|||Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS04815 ^@ http://purl.uniprot.org/uniprot/A0A8D4N3P5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS09885 ^@ http://purl.uniprot.org/uniprot/A0A386HEF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 5 family.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS15390 ^@ http://purl.uniprot.org/uniprot/A0A386HH61 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1604335:DXZ79_RS12745 ^@ http://purl.uniprot.org/uniprot/A0A386HGH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS05050 ^@ http://purl.uniprot.org/uniprot/A0A8D4MZI4 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/1604335:DXZ79_RS18405 ^@ http://purl.uniprot.org/uniprot/A0A386HIX8 ^@ Function|||Subunit ^@ Homotetramer.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/1604335:DXZ79_RS12250 ^@ http://purl.uniprot.org/uniprot/A0A386HF15 ^@ Function|||Similarity ^@ Belongs to the DUF177 domain family.|||Plays a role in synthesis, processing and/or stability of 23S rRNA. http://togogenome.org/gene/1604335:DXZ79_RS05775 ^@ http://purl.uniprot.org/uniprot/A0A8D4SME0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M20A family. DapE subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS14910 ^@ http://purl.uniprot.org/uniprot/A0A8E4GYB2 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). http://togogenome.org/gene/1604335:DXZ79_RS09620 ^@ http://purl.uniprot.org/uniprot/A0A386HE93 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/1604335:DXZ79_RS04240 ^@ http://purl.uniprot.org/uniprot/A0A8D4N052 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1604335:DXZ79_RS00925 ^@ http://purl.uniprot.org/uniprot/A0A386H9Y3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. WecA subfamily.|||Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS02365 ^@ http://purl.uniprot.org/uniprot/A0A386HAW3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS02135 ^@ http://purl.uniprot.org/uniprot/A0A386HA04 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/1604335:DXZ79_RS12570 ^@ http://purl.uniprot.org/uniprot/A0A386HF56 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.|||Cytoplasm|||Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity. http://togogenome.org/gene/1604335:DXZ79_RS08790 ^@ http://purl.uniprot.org/uniprot/A0A386HDK8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family.|||Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS16180 ^@ http://purl.uniprot.org/uniprot/A0A8D4ST59 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/1604335:DXZ79_RS07435 ^@ http://purl.uniprot.org/uniprot/A0A386HCK7 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer.|||Toroid-shaped homodecamer, composed of two pentamers of five dimers. http://togogenome.org/gene/1604335:DXZ79_RS17055 ^@ http://purl.uniprot.org/uniprot/A0A386HIM3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS12035 ^@ http://purl.uniprot.org/uniprot/A0A386HFP4 ^@ Similarity|||Subunit ^@ Belongs to the Nudix hydrolase family. NudJ subfamily.|||Monomer. http://togogenome.org/gene/1604335:DXZ79_RS04585 ^@ http://purl.uniprot.org/uniprot/A0A386HBQ6 ^@ Function ^@ Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. http://togogenome.org/gene/1604335:DXZ79_RS09955 ^@ http://purl.uniprot.org/uniprot/A0A386HEG6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YciB family.|||Cell inner membrane|||Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. http://togogenome.org/gene/1604335:DXZ79_RS08795 ^@ http://purl.uniprot.org/uniprot/A0A386HDV2 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1604335:DXZ79_RS10105 ^@ http://purl.uniprot.org/uniprot/A0A386HE63 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1604335:DXZ79_RS07730 ^@ http://purl.uniprot.org/uniprot/A0A386HDK9 ^@ Cofactor ^@ Binds 2 Mg(2+) ions per monomer. http://togogenome.org/gene/1604335:DXZ79_RS03560 ^@ http://purl.uniprot.org/uniprot/A0A386HB72 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/1604335:DXZ79_RS06815 ^@ http://purl.uniprot.org/uniprot/A0A386HD38 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TolB family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.|||Periplasm|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/1604335:DXZ79_RS05360 ^@ http://purl.uniprot.org/uniprot/A0A386HC22 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS18115 ^@ http://purl.uniprot.org/uniprot/A0A386HJ58 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1604335:DXZ79_RS16140 ^@ http://purl.uniprot.org/uniprot/A0A386HGW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS00625 ^@ http://purl.uniprot.org/uniprot/A0A386H9H7 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/1604335:DXZ79_RS05745 ^@ http://purl.uniprot.org/uniprot/A0A386HCH7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS08110 ^@ http://purl.uniprot.org/uniprot/A0A386HDH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the periplasmic pilus chaperone family.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS03665 ^@ http://purl.uniprot.org/uniprot/A0A386HB94 ^@ Similarity ^@ Belongs to the DNA polymerase type-B family. http://togogenome.org/gene/1604335:DXZ79_RS15665 ^@ http://purl.uniprot.org/uniprot/A0A8D4SST8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Syd family.|||Cell inner membrane|||Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. http://togogenome.org/gene/1604335:DXZ79_RS00265 ^@ http://purl.uniprot.org/uniprot/A0A386H9P2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1604335:DXZ79_RS11250 ^@ http://purl.uniprot.org/uniprot/A0A386HEF3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArnF family.|||Cell inner membrane|||Heterodimer of ArnE and ArnF.|||Membrane|||Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane. http://togogenome.org/gene/1604335:DXZ79_RS00825 ^@ http://purl.uniprot.org/uniprot/A0A386HA73 ^@ Function|||Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.|||Homotetramer. http://togogenome.org/gene/1604335:DXZ79_RS11075 ^@ http://purl.uniprot.org/uniprot/A0A386HF10 ^@ Domain|||Function|||Subunit ^@ Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.|||Homodimer.|||Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. http://togogenome.org/gene/1604335:DXZ79_RS05950 ^@ http://purl.uniprot.org/uniprot/A0A386HC03 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Membrane|||Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). http://togogenome.org/gene/1604335:DXZ79_RS08490 ^@ http://purl.uniprot.org/uniprot/A0A386HDN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS02345 ^@ http://purl.uniprot.org/uniprot/A0A386HAG7 ^@ Function|||Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily.|||HflC and HflK could regulate a protease. http://togogenome.org/gene/1604335:DXZ79_RS14605 ^@ http://purl.uniprot.org/uniprot/A0A8D4N2C2 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1604335:DXZ79_RS01050 ^@ http://purl.uniprot.org/uniprot/A0A386H9V2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS20480 ^@ http://purl.uniprot.org/uniprot/A0A386HJY7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PstS family.|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/1604335:DXZ79_RS12465 ^@ http://purl.uniprot.org/uniprot/A0A386HFY6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HspQ family.|||Cytoplasm|||Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress. http://togogenome.org/gene/1604335:DXZ79_RS06480 ^@ http://purl.uniprot.org/uniprot/A0A386HCH6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS19420 ^@ http://purl.uniprot.org/uniprot/A0A386HIX3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell inner membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/1604335:DXZ79_RS01420 ^@ http://purl.uniprot.org/uniprot/A0A386HA83 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RfaH family.|||Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.|||Interacts with both the nontemplate DNA and the RNA polymerase (RNAP). http://togogenome.org/gene/1604335:DXZ79_RS02440 ^@ http://purl.uniprot.org/uniprot/A0A8D4MXC3 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/1604335:DXZ79_RS11470 ^@ http://purl.uniprot.org/uniprot/A0A386HEP2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the KduI family.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. http://togogenome.org/gene/1604335:DXZ79_RS14925 ^@ http://purl.uniprot.org/uniprot/A0A386HH69 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.|||Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers. http://togogenome.org/gene/1604335:DXZ79_RS05115 ^@ http://purl.uniprot.org/uniprot/A0A386HC64 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamE family.|||Cell outer membrane|||Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/1604335:DXZ79_RS06680 ^@ http://purl.uniprot.org/uniprot/A0A386HC76 ^@ Similarity ^@ Belongs to the DNA photolyase class-1 family.|||Belongs to the DNA photolyase family. http://togogenome.org/gene/1604335:DXZ79_RS12445 ^@ http://purl.uniprot.org/uniprot/A0A386HEZ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dsrC/tusE family.|||Cytoplasm|||Interacts with the TusBCD complex. Interacts with MnmA.|||Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD. http://togogenome.org/gene/1604335:DXZ79_RS18540 ^@ http://purl.uniprot.org/uniprot/A0A386HJD8 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/1604335:DXZ79_RS04155 ^@ http://purl.uniprot.org/uniprot/A0A386HB09 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.|||Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS18550 ^@ http://purl.uniprot.org/uniprot/A0A8D4N4Y8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TPS (TC 1.B.20) family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS07915 ^@ http://purl.uniprot.org/uniprot/A0A386HD84 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/1604335:DXZ79_RS01340 ^@ http://purl.uniprot.org/uniprot/A0A386H9N8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LysR transcriptional regulatory family.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS19580 ^@ http://purl.uniprot.org/uniprot/A0A386HJ01 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/1604335:DXZ79_RS12315 ^@ http://purl.uniprot.org/uniprot/A0A386HFB4 ^@ Function|||Similarity ^@ Belongs to the TrhO family.|||Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs. http://togogenome.org/gene/1604335:DXZ79_RS03210 ^@ http://purl.uniprot.org/uniprot/A0A386HAN7 ^@ Cofactor|||Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1604335:DXZ79_RS02230 ^@ http://purl.uniprot.org/uniprot/A0A8D4MZF7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the calycin superfamily. Lipocalin family.|||Cell outer membrane|||Homodimer.|||Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids. http://togogenome.org/gene/1604335:DXZ79_RS12245 ^@ http://purl.uniprot.org/uniprot/A0A386HFU8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1604335:DXZ79_RS00850 ^@ http://purl.uniprot.org/uniprot/A0A8E4BM84 ^@ Similarity ^@ Belongs to the colicins ColE2/ColE8/ColE9 and pyocins S1/S2 family. http://togogenome.org/gene/1604335:DXZ79_RS15015 ^@ http://purl.uniprot.org/uniprot/A0A386HGX0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the branched chain amino acid transporter family.|||Cell inner membrane|||Component of the transport system for branched-chain amino acids.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS09890 ^@ http://purl.uniprot.org/uniprot/A0A386HDT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS17820 ^@ http://purl.uniprot.org/uniprot/A0A386HIM1 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/1604335:DXZ79_RS03375 ^@ http://purl.uniprot.org/uniprot/A0A386HAK2 ^@ Similarity ^@ Belongs to the Smp family. http://togogenome.org/gene/1604335:DXZ79_RS14790 ^@ http://purl.uniprot.org/uniprot/A0A386HG71 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1604335:DXZ79_RS09050 ^@ http://purl.uniprot.org/uniprot/A0A386HDQ9 ^@ Similarity ^@ Belongs to the four-carbon acid sugar kinase family. http://togogenome.org/gene/1604335:DXZ79_RS08680 ^@ http://purl.uniprot.org/uniprot/A0A8D4N458 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliO/MopB family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS07220 ^@ http://purl.uniprot.org/uniprot/A0A386HCM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1604335:DXZ79_RS17990 ^@ http://purl.uniprot.org/uniprot/A0A386HIQ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS02165 ^@ http://purl.uniprot.org/uniprot/A0A386HAW4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbD subfamily.|||Cell inner membrane|||Membrane|||Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. http://togogenome.org/gene/1604335:DXZ79_RS01035 ^@ http://purl.uniprot.org/uniprot/A0A386H9P1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adenylyl cyclase class-1 family.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS12045 ^@ http://purl.uniprot.org/uniprot/A0A386HFC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HflD family.|||Cell membrane|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS13640 ^@ http://purl.uniprot.org/uniprot/A0A386HFL8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/1604335:DXZ79_RS00955 ^@ http://purl.uniprot.org/uniprot/A0A386HA05 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the WecD family.|||Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1604335:DXZ79_RS06440 ^@ http://purl.uniprot.org/uniprot/A0A386HC60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS03405 ^@ http://purl.uniprot.org/uniprot/A0A386HB56 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. http://togogenome.org/gene/1604335:DXZ79_RS04315 ^@ http://purl.uniprot.org/uniprot/A0A386HBF2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS09520 ^@ http://purl.uniprot.org/uniprot/A0A386HDR5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/1604335:DXZ79_RS10915 ^@ http://purl.uniprot.org/uniprot/A0A386HF37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS00500 ^@ http://purl.uniprot.org/uniprot/A0A386H9U0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic sulfate-binding protein family.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS03470 ^@ http://purl.uniprot.org/uniprot/A0A386HJL3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS04010 ^@ http://purl.uniprot.org/uniprot/A0A8D4N3F2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer. http://togogenome.org/gene/1604335:DXZ79_RS05450 ^@ http://purl.uniprot.org/uniprot/A0A386HBM6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RodZ family.|||Cell inner membrane|||Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.|||The helix-turn-helix (HTH) motif in the cytoplasmic domain of the N-terminus is involved in the formation of spirals to maintain the rigid rod shape. As this protein is anchored in the cytoplasmic membrane, the HTH motif may contribute to protein-protein interactions to form the RodZ helix, which is localized beneath the cytoplasmic membrane. The C-terminal domain may be critical for determination of the rod shape by probably interacting with enzymes required for synthesis of the peptidoglycan layer, including PBPs in the periplasm. http://togogenome.org/gene/1604335:DXZ79_RS04510 ^@ http://purl.uniprot.org/uniprot/A0A386HBW8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS19770 ^@ http://purl.uniprot.org/uniprot/A0A386HJC0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RlmJ family.|||Monomer.|||Specifically methylates the adenine in position 2030 of 23S rRNA. http://togogenome.org/gene/1604335:DXZ79_RS10255 ^@ http://purl.uniprot.org/uniprot/A0A386HE28 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.|||Binds 3 [4Fe-4S] clusters.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1604335:DXZ79_RS07460 ^@ http://purl.uniprot.org/uniprot/A0A386HCS1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.|||Cell inner membrane|||Membrane|||Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB). http://togogenome.org/gene/1604335:DXZ79_RS04615 ^@ http://purl.uniprot.org/uniprot/A0A386HBY8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/1604335:DXZ79_RS19740 ^@ http://purl.uniprot.org/uniprot/A0A386HKN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein B family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS01315 ^@ http://purl.uniprot.org/uniprot/A0A386HA88 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family. UgpAE subfamily.|||Cell inner membrane|||Cell membrane|||Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB). http://togogenome.org/gene/1604335:DXZ79_RS05610 ^@ http://purl.uniprot.org/uniprot/A0A386HBQ5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||Cell inner membrane|||Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. http://togogenome.org/gene/1604335:DXZ79_RS14855 ^@ http://purl.uniprot.org/uniprot/A0A386HGV5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase bacterial subunit 4 family.|||Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.|||Heterooctamer of two A chains, two B chains, two C chains and two D chains.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS11335 ^@ http://purl.uniprot.org/uniprot/A0A386HEM3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1604335:DXZ79_RS03515 ^@ http://purl.uniprot.org/uniprot/A0A386HAU3 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1604335:DXZ79_RS17030 ^@ http://purl.uniprot.org/uniprot/A0A386HHZ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1604335:DXZ79_RS02210 ^@ http://purl.uniprot.org/uniprot/A0A8D4N1F2 ^@ Similarity ^@ Belongs to the radical SAM superfamily. KamA family. http://togogenome.org/gene/1604335:DXZ79_RS10270 ^@ http://purl.uniprot.org/uniprot/A0A386HE92 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/1604335:DXZ79_RS14050 ^@ http://purl.uniprot.org/uniprot/A0A386HGC6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS13230 ^@ http://purl.uniprot.org/uniprot/A0A8D4SSF2 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1604335:DXZ79_RS08585 ^@ http://purl.uniprot.org/uniprot/A0A386HDT8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell inner membrane|||Cell membrane|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/1604335:DXZ79_RS18370 ^@ http://purl.uniprot.org/uniprot/A0A386HIG7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS19565 ^@ http://purl.uniprot.org/uniprot/A0A386HJ29 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/1604335:DXZ79_RS02645 ^@ http://purl.uniprot.org/uniprot/A0A8D4SQP1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1604335:DXZ79_RS00610 ^@ http://purl.uniprot.org/uniprot/A0A386HA44 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MetJ family.|||Cytoplasm|||Does not bind DNA by a helix-turn-helix motif.|||Homodimer.|||This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. http://togogenome.org/gene/1604335:DXZ79_RS18905 ^@ http://purl.uniprot.org/uniprot/A0A386HJI8 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1604335:DXZ79_RS04265 ^@ http://purl.uniprot.org/uniprot/A0A386HBI8 ^@ Function|||Similarity ^@ Belongs to the precorrin methyltransferase family.|||In the C-terminal section; belongs to the precorrin methyltransferase family.|||In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.|||Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. http://togogenome.org/gene/1604335:DXZ79_RS09410 ^@ http://purl.uniprot.org/uniprot/A0A386HE52 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily.|||Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.|||Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS14635 ^@ http://purl.uniprot.org/uniprot/A0A386HGW8 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1604335:DXZ79_RS05940 ^@ http://purl.uniprot.org/uniprot/A0A386HC92 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic sulfate-binding protein family.|||Periplasm http://togogenome.org/gene/1604335:DXZ79_RS16095 ^@ http://purl.uniprot.org/uniprot/A0A386HHH9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioredoxin family. DsbC subfamily.|||Periplasm|||Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. http://togogenome.org/gene/1604335:DXZ79_RS09175 ^@ http://purl.uniprot.org/uniprot/A0A386HDF7 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/1604335:DXZ79_RS02375 ^@ http://purl.uniprot.org/uniprot/A0A8D4SPM7 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1604335:DXZ79_RS07910 ^@ http://purl.uniprot.org/uniprot/A0A386HCZ1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS12190 ^@ http://purl.uniprot.org/uniprot/A0A8D4N526 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/1604335:DXZ79_RS05255 ^@ http://purl.uniprot.org/uniprot/A0A386HCA7 ^@ Function|||Induction|||Miscellaneous|||Similarity|||Subunit ^@ A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.|||Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.|||Homodimer.|||Induced by MurNAc 6-phosphate that releases the repressor MurR from the DNA. Repressed by MurR in the absence of MurNAc 6-phosphate.|||Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. http://togogenome.org/gene/1604335:DXZ79_RS06400 ^@ http://purl.uniprot.org/uniprot/A0A386HCT7 ^@ Function|||Similarity ^@ Belongs to the RlpA family.|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/1604335:DXZ79_RS00570 ^@ http://purl.uniprot.org/uniprot/A0A8D4N0W1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MenA family. Type 1 subfamily.|||Cell membrane|||Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS16910 ^@ http://purl.uniprot.org/uniprot/A0A386HHX9 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/1604335:DXZ79_RS07895 ^@ http://purl.uniprot.org/uniprot/A0A386HDH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS16160 ^@ http://purl.uniprot.org/uniprot/A0A386HGZ5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1604335:DXZ79_RS20335 ^@ http://purl.uniprot.org/uniprot/A0A386HK87 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1604335:DXZ79_RS03360 ^@ http://purl.uniprot.org/uniprot/A0A8E4BMI5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer.|||The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. http://togogenome.org/gene/1604335:DXZ79_RS20525 ^@ http://purl.uniprot.org/uniprot/A0A386HJU7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS14735 ^@ http://purl.uniprot.org/uniprot/A0A386HGR8 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1604335:DXZ79_RS05840 ^@ http://purl.uniprot.org/uniprot/A0A8D4N3Z5 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.|||Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.|||Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.|||Periplasm|||Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven. http://togogenome.org/gene/1604335:DXZ79_RS05985 ^@ http://purl.uniprot.org/uniprot/A0A386HC46 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1604335:DXZ79_RS01450 ^@ http://purl.uniprot.org/uniprot/A0A8D4N1Q7 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/1604335:DXZ79_RS01625 ^@ http://purl.uniprot.org/uniprot/A0A386H9Y5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS11800 ^@ http://purl.uniprot.org/uniprot/A0A386HFG8 ^@ Similarity ^@ Belongs to the UPF0053 family. http://togogenome.org/gene/1604335:DXZ79_RS06935 ^@ http://purl.uniprot.org/uniprot/A0A386HD10 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1604335:DXZ79_RS18425 ^@ http://purl.uniprot.org/uniprot/A0A386HIH2 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/1604335:DXZ79_RS18175 ^@ http://purl.uniprot.org/uniprot/A0A386HIK7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/1604335:DXZ79_RS13070 ^@ http://purl.uniprot.org/uniprot/A0A386HFG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/1604335:DXZ79_RS19800 ^@ http://purl.uniprot.org/uniprot/A0A386HJL5 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/1604335:DXZ79_RS17640 ^@ http://purl.uniprot.org/uniprot/A0A386HIJ3 ^@ Similarity ^@ Belongs to the UxaA family. http://togogenome.org/gene/1604335:DXZ79_RS13395 ^@ http://purl.uniprot.org/uniprot/A0A386HFZ9 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. http://togogenome.org/gene/1604335:DXZ79_RS08525 ^@ http://purl.uniprot.org/uniprot/A0A386HDQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/1604335:DXZ79_RS05960 ^@ http://purl.uniprot.org/uniprot/A0A8E3ZHQ8 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1604335:DXZ79_RS17180 ^@ http://purl.uniprot.org/uniprot/A0A386HI30 ^@ Similarity ^@ Belongs to the bacterial secretin family. http://togogenome.org/gene/1604335:DXZ79_RS00510 ^@ http://purl.uniprot.org/uniprot/A0A386H9G1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/1604335:DXZ79_RS05325 ^@ http://purl.uniprot.org/uniprot/A0A8D4N343 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1604335:DXZ79_RS15405 ^@ http://purl.uniprot.org/uniprot/A0A386HH63 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1604335:DXZ79_RS07850 ^@ http://purl.uniprot.org/uniprot/A0A386HDM6 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial microcompartment|||Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/1604335:DXZ79_RS00070 ^@ http://purl.uniprot.org/uniprot/A0A386H9W2 ^@ Activity Regulation|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/1604335:DXZ79_RS18145 ^@ http://purl.uniprot.org/uniprot/A0A386HIM4 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape.