http://togogenome.org/gene/1580092:NADRNF5_RS04920 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2S7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS02125 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0M5 ^@ Similarity ^@ Belongs to the PDCD5 family. http://togogenome.org/gene/1580092:NADRNF5_RS05940 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2B3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS09025 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5A9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA polymerase beta chain family.|||Cytoplasm|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/1580092:NADRNF5_RS05375 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3B3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS04165 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2J8 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/1580092:NADRNF5_RS09345 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5J7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS01235 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZH8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. http://togogenome.org/gene/1580092:NADRNF5_RS00270 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZZ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrcB (TC 9.B.71) family.|||Cell membrane|||Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane http://togogenome.org/gene/1580092:NADRNF5_RS00915 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0N7 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. http://togogenome.org/gene/1580092:NADRNF5_RS04895 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1U5 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/1580092:NADRNF5_RS09175 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5H2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.|||Binds 1 zinc ion.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/1580092:NADRNF5_RS10570 ^@ http://purl.uniprot.org/uniprot/A0A0D5C502 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS6 family. http://togogenome.org/gene/1580092:NADRNF5_RS02425 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0E1 ^@ Caution|||Function|||Similarity ^@ Belongs to the eukaryotic RecA-like protein family.|||Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS02965 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1Q9 ^@ Similarity ^@ Belongs to the type IB topoisomerase family. http://togogenome.org/gene/1580092:NADRNF5_RS01470 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZW0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Membrane http://togogenome.org/gene/1580092:NADRNF5_RS03125 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1C6 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1580092:NADRNF5_RS01360 ^@ http://purl.uniprot.org/uniprot/A0A0D5C090 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/1580092:NADRNF5_RS00825 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZA3 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1580092:NADRNF5_RS08560 ^@ http://purl.uniprot.org/uniprot/A0A0D5C506 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1580092:NADRNF5_RS04325 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1B9 ^@ Caution|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the FBP aldolase/phosphatase family.|||Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).|||Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.|||Homooctamer; dimer of tetramers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS08465 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4J0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS5 family. http://togogenome.org/gene/1580092:NADRNF5_RS04880 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2R7 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/1580092:NADRNF5_RS08515 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4J8 ^@ Function ^@ Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. http://togogenome.org/gene/1580092:NADRNF5_RS09605 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5L9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS03940 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1S6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Archaeal flagellum|||Belongs to the archaeal flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella. http://togogenome.org/gene/1580092:NADRNF5_RS08235 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4U8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS07890 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4P2 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1580092:NADRNF5_RS03360 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1H2 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the MRE11/RAD32 family.|||Binds 2 manganese ions per subunit.|||Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nuclease activity is regulated by Rad50.|||Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. http://togogenome.org/gene/1580092:NADRNF5_RS01565 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZP0 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/1580092:NADRNF5_RS02350 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0C9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1580092:NADRNF5_RS04140 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2J3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1580092:NADRNF5_RS01135 ^@ http://purl.uniprot.org/uniprot/A0A0D5C052 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS10410 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4Y0 ^@ Similarity ^@ Belongs to the AAA ATPase family. CDC48 subfamily. http://togogenome.org/gene/1580092:NADRNF5_RS01305 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0N5 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/1580092:NADRNF5_RS00715 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZH6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycerol-1-phosphate dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS03475 ^@ http://purl.uniprot.org/uniprot/A0A0D5C128 ^@ Function|||Similarity ^@ Belongs to the EF-1-beta/EF-1-delta family.|||Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. http://togogenome.org/gene/1580092:NADRNF5_RS09510 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5N1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.|||Belongs to the histone-like Alba family.|||Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.|||Chromosome|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1580092:NADRNF5_RS01480 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZM6 ^@ Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Homodimer. http://togogenome.org/gene/1580092:NADRNF5_RS10205 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5K2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS03405 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1Y5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the archaeal Spt4 family.|||Heterodimer composed of Spt4 and Spt5.|||Stimulates transcription elongation. http://togogenome.org/gene/1580092:NADRNF5_RS06745 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3G6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1580092:NADRNF5_RS02145 ^@ http://purl.uniprot.org/uniprot/A0A0D5C145 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/1580092:NADRNF5_RS04810 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2Q2 ^@ Function|||Similarity ^@ Belongs to the TBP family.|||General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. http://togogenome.org/gene/1580092:NADRNF5_RS05945 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3L7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS00120 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZH3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1580092:NADRNF5_RS00940 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZM1 ^@ Similarity|||Subunit ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.|||Heterooligomer of catalytic and regulatory chains. http://togogenome.org/gene/1580092:NADRNF5_RS08830 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4Q0 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1580092:NADRNF5_RS10135 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4R8 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1580092:NADRNF5_RS06565 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3Z2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/1580092:NADRNF5_RS07905 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4S8 ^@ Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS8 family.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1580092:NADRNF5_RS01880 ^@ http://purl.uniprot.org/uniprot/A0A0D5C039 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1580092:NADRNF5_RS08580 ^@ http://purl.uniprot.org/uniprot/A0A0D5C509 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion. http://togogenome.org/gene/1580092:NADRNF5_RS04715 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2N2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1580092:NADRNF5_RS08470 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3T5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1580092:NADRNF5_RS07730 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4P8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1580092:NADRNF5_RS01770 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0F9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TYW1 family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).|||Cytoplasm|||Monomer. http://togogenome.org/gene/1580092:NADRNF5_RS08460 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4Y8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL30 family. http://togogenome.org/gene/1580092:NADRNF5_RS01225 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0M2 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/1580092:NADRNF5_RS00720 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0C7 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.|||The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/1580092:NADRNF5_RS07420 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4B8 ^@ Function|||Similarity ^@ Belongs to the TBP family.|||General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. http://togogenome.org/gene/1580092:NADRNF5_RS06885 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2V5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS03905 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1A4 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1580092:NADRNF5_RS09250 ^@ http://purl.uniprot.org/uniprot/A0A0D5C482 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/1580092:NADRNF5_RS06025 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2L4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29. http://togogenome.org/gene/1580092:NADRNF5_RS04305 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2M1 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/1580092:NADRNF5_RS00310 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0A4 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/1580092:NADRNF5_RS07175 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4B1 ^@ Similarity ^@ Belongs to the glutaredoxin family. http://togogenome.org/gene/1580092:NADRNF5_RS01645 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS00125 ^@ http://purl.uniprot.org/uniprot/A0A0D5BYU9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS03005 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1X5 ^@ Similarity ^@ Belongs to the peptidase T1A family. http://togogenome.org/gene/1580092:NADRNF5_RS06750 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2S5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1580092:NADRNF5_RS00345 ^@ http://purl.uniprot.org/uniprot/A0A0D5C019 ^@ Function|||Similarity ^@ Belongs to the CDC6/cdc18 family.|||Involved in regulation of DNA replication. http://togogenome.org/gene/1580092:NADRNF5_RS09140 ^@ http://purl.uniprot.org/uniprot/A0A0D5C463 ^@ Similarity ^@ Belongs to the UPF0284 family. http://togogenome.org/gene/1580092:NADRNF5_RS04740 ^@ http://purl.uniprot.org/uniprot/A0A0D5C272 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS02390 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0S7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/1580092:NADRNF5_RS02060 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZY1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/1580092:NADRNF5_RS00910 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZB8 ^@ Function|||Similarity ^@ Belongs to the V-ATPase E subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1580092:NADRNF5_RS00925 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0G2 ^@ Function|||Similarity ^@ Belongs to the V-ATPase D subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1580092:NADRNF5_RS07250 ^@ http://purl.uniprot.org/uniprot/A0A0D5C479 ^@ Caution|||Function|||Similarity ^@ Belongs to the TFIIB family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). http://togogenome.org/gene/1580092:NADRNF5_RS06030 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3H7 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1580092:NADRNF5_RS08520 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3U5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DtdA deacylase family.|||Binds 2 Zn(2+) ions per subunit.|||D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.|||Monomer. http://togogenome.org/gene/1580092:NADRNF5_RS00920 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZL6 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. http://togogenome.org/gene/1580092:NADRNF5_RS06005 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2K9 ^@ Similarity ^@ Belongs to the peptidase T1A family. http://togogenome.org/gene/1580092:NADRNF5_RS05800 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3D0 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/1580092:NADRNF5_RS01980 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0J4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic CoaD family.|||Cytoplasm|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1580092:NADRNF5_RS06945 ^@ http://purl.uniprot.org/uniprot/A0A0D5C342 ^@ Similarity ^@ Belongs to the malic enzymes family. http://togogenome.org/gene/1580092:NADRNF5_RS07965 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4Q3 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/1580092:NADRNF5_RS05925 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3L2 ^@ Similarity ^@ Belongs to the glutaredoxin family. http://togogenome.org/gene/1580092:NADRNF5_RS01735 ^@ http://purl.uniprot.org/uniprot/A0A0D5C010 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the archaeosine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS04310 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1I5 ^@ Function|||Similarity ^@ Belongs to the ATP-dependent DNA ligase family.|||DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. http://togogenome.org/gene/1580092:NADRNF5_RS05390 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2Q6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS01025 ^@ http://purl.uniprot.org/uniprot/A0A0D5C031 ^@ Subunit ^@ Homotrimer. http://togogenome.org/gene/1580092:NADRNF5_RS01740 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0W6 ^@ Caution|||Function|||Similarity ^@ Belongs to the adenylate kinase family. AK6 subfamily.|||Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS10530 ^@ http://purl.uniprot.org/uniprot/A0A0D5C589 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/1580092:NADRNF5_RS09205 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4H5 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1580092:NADRNF5_RS08530 ^@ http://purl.uniprot.org/uniprot/A0A0D5C441 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SPT5 family.|||Belongs to the archaeal Spt5 family.|||Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).|||Stimulates transcription elongation. http://togogenome.org/gene/1580092:NADRNF5_RS09870 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5A5 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1580092:NADRNF5_RS03200 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1E1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.|||Cytoplasm|||Involved in both the arginine and lysine biosynthetic pathways.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS08430 ^@ http://purl.uniprot.org/uniprot/A0A0D5C422 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.|||Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/1580092:NADRNF5_RS07725 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3E5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS00580 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZ59 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/1580092:NADRNF5_RS09070 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4F6 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. http://togogenome.org/gene/1580092:NADRNF5_RS08115 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4S7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS03410 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1I3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.|||Nucleus|||Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure. http://togogenome.org/gene/1580092:NADRNF5_RS09695 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5N7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NDK family.|||Cytoplasm|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/1580092:NADRNF5_RS05150 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2H2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Binds 2 Mg(2+) or Mn(2+) ions per subunit.|||Catalyzes the formation of archaetidylinositol phosphate (AIP) from CDP-archaeol (CDP-ArOH or CDP-2,3-bis-(O-phytanyl)-sn-glycerol) and 1L-myo-inositol 1-phosphate (IP or 1D-myo-inositol 3-phosphate). AIP is a precursor of archaetidyl-myo-inositol (AI), an ether-type inositol phospholipid ubiquitously distributed in archaea membranes and essential for glycolipid biosynthesis in archaea.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS00225 ^@ http://purl.uniprot.org/uniprot/A0A0D5BYW7 ^@ Function|||Similarity ^@ Belongs to the APS kinase family.|||Catalyzes the synthesis of activated sulfate. http://togogenome.org/gene/1580092:NADRNF5_RS10295 ^@ http://purl.uniprot.org/uniprot/A0A0D5C645 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS06205 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2G6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Forms a complex with TatA.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. http://togogenome.org/gene/1580092:NADRNF5_RS08285 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4V6 ^@ Similarity ^@ Belongs to the SDO1/SBDS family. http://togogenome.org/gene/1580092:NADRNF5_RS10210 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4T8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/1580092:NADRNF5_RS08260 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4V4 ^@ Similarity ^@ Belongs to the CTAG/PCC1 family. http://togogenome.org/gene/1580092:NADRNF5_RS02315 ^@ http://purl.uniprot.org/uniprot/A0A0D5C038 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TOP6A family.|||Homodimer. Heterotetramer of two Top6A and two Top6B chains.|||Relaxes both positive and negative superturns and exhibits a strong decatenase activity. http://togogenome.org/gene/1580092:NADRNF5_RS07720 ^@ http://purl.uniprot.org/uniprot/A0A0D5C450 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS08480 ^@ http://purl.uniprot.org/uniprot/A0A0D5C431 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/1580092:NADRNF5_RS02435 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0T7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL21 family. http://togogenome.org/gene/1580092:NADRNF5_RS10440 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4Y3 ^@ Function|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1580092:NADRNF5_RS09110 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4W4 ^@ Subunit ^@ Homotrimer. http://togogenome.org/gene/1580092:NADRNF5_RS00300 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZL4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1580092:NADRNF5_RS10150 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5Z3 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/1580092:NADRNF5_RS01610 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0U1 ^@ Similarity ^@ Belongs to the HMG-CoA reductase family. http://togogenome.org/gene/1580092:NADRNF5_RS02980 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1X0 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1580092:NADRNF5_RS08305 ^@ http://purl.uniprot.org/uniprot/A0A0D5C403 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/1580092:NADRNF5_RS10610 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5A3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/1580092:NADRNF5_RS09565 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5N9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. Hel308 subfamily.|||DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.|||Monomer. http://togogenome.org/gene/1580092:NADRNF5_RS08985 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5D7 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1580092:NADRNF5_RS07740 ^@ http://purl.uniprot.org/uniprot/A0A0D5C456 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/1580092:NADRNF5_RS03170 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1U7 ^@ Similarity ^@ Belongs to the RimK family. LysX subfamily. http://togogenome.org/gene/1580092:NADRNF5_RS10355 ^@ http://purl.uniprot.org/uniprot/A0A0D5C626 ^@ Similarity ^@ Belongs to the transcriptional regulator TrmB family. http://togogenome.org/gene/1580092:NADRNF5_RS07525 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4I1 ^@ Cofactor|||Similarity ^@ Belongs to the ELP3 family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1580092:NADRNF5_RS05915 ^@ http://purl.uniprot.org/uniprot/A0A0D5C309 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS04225 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2D6 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/1580092:NADRNF5_RS00465 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0F7 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ 2 residues (Tyr-64 and Arg-67) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.|||Belongs to the sirtuin family. Class III subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. http://togogenome.org/gene/1580092:NADRNF5_RS07085 ^@ http://purl.uniprot.org/uniprot/A0A0D5C442 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/1580092:NADRNF5_RS03945 ^@ http://purl.uniprot.org/uniprot/A0A0D5C143 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Archaeal flagellum|||Belongs to the archaeal flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella. http://togogenome.org/gene/1580092:NADRNF5_RS10375 ^@ http://purl.uniprot.org/uniprot/A0A0D5C629 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic release factor 1 family. Pelota subfamily.|||Cytoplasm|||May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.|||Monomer.|||The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity. http://togogenome.org/gene/1580092:NADRNF5_RS08725 ^@ http://purl.uniprot.org/uniprot/A0A0D5C478 ^@ Similarity ^@ Belongs to the PstS family. http://togogenome.org/gene/1580092:NADRNF5_RS02120 ^@ http://purl.uniprot.org/uniprot/A0A0D5C141 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit.|||Monomer. http://togogenome.org/gene/1580092:NADRNF5_RS10500 ^@ http://purl.uniprot.org/uniprot/A0A0D5C681 ^@ Similarity ^@ Belongs to the AdoMet synthase family. http://togogenome.org/gene/1580092:NADRNF5_RS09125 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4G3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1580092:NADRNF5_RS04510 ^@ http://purl.uniprot.org/uniprot/A0A0D5C232 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/1580092:NADRNF5_RS07715 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4L0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type-I 3-dehydroquinase family.|||Homodimer.|||Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS03965 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1T0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Archaeal flagellum|||Belongs to the archaeal flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella. http://togogenome.org/gene/1580092:NADRNF5_RS08490 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4J3 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/1580092:NADRNF5_RS00480 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZS1 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/1580092:NADRNF5_RS07870 ^@ http://purl.uniprot.org/uniprot/A0A0D5C481 ^@ Function|||Similarity ^@ Belongs to the eIF-1A family.|||Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. http://togogenome.org/gene/1580092:NADRNF5_RS01685 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0V6 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1580092:NADRNF5_RS03230 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0Q9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1580092:NADRNF5_RS09180 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4H2 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1580092:NADRNF5_RS03420 ^@ http://purl.uniprot.org/uniprot/A0A0D5C250 ^@ Function|||Similarity ^@ Belongs to the GTP-dependent DPCK family.|||Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). http://togogenome.org/gene/1580092:NADRNF5_RS04060 ^@ http://purl.uniprot.org/uniprot/A0A0D5C165 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1580092:NADRNF5_RS09705 ^@ http://purl.uniprot.org/uniprot/A0A0D5C571 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS28 family. http://togogenome.org/gene/1580092:NADRNF5_RS09055 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4V2 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. http://togogenome.org/gene/1580092:NADRNF5_RS05425 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3C1 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/1580092:NADRNF5_RS05220 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2Z5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS00385 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0C0 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/1580092:NADRNF5_RS02580 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1L7 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1580092:NADRNF5_RS03195 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1V1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. LysZ subfamily.|||Cytoplasm|||Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis). http://togogenome.org/gene/1580092:NADRNF5_RS06535 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2M8 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/1580092:NADRNF5_RS06065 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2D7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||Located at the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1580092:NADRNF5_RS02345 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1G5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Homohexamer. Dimer of a homotrimer. http://togogenome.org/gene/1580092:NADRNF5_RS05710 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2F5 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/1580092:NADRNF5_RS00890 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0N2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Membrane http://togogenome.org/gene/1580092:NADRNF5_RS03300 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0Z5 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1580092:NADRNF5_RS07285 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4D6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).|||Belongs to the TDD superfamily. TSR3 family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS06040 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2D3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1580092:NADRNF5_RS03150 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1D1 ^@ Function|||Similarity ^@ Belongs to the archaeal riboflavin kinase family.|||Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN). http://togogenome.org/gene/1580092:NADRNF5_RS06015 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2C7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e. http://togogenome.org/gene/1580092:NADRNF5_RS06020 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3N2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL4 family. http://togogenome.org/gene/1580092:NADRNF5_RS00095 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZG7 ^@ Function ^@ Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor. http://togogenome.org/gene/1580092:NADRNF5_RS01650 ^@ http://purl.uniprot.org/uniprot/A0A0D5C129 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/1580092:NADRNF5_RS04155 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1W3 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1580092:NADRNF5_RS07095 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2Z4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1580092:NADRNF5_RS00710 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0J9 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1580092:NADRNF5_RS08535 ^@ http://purl.uniprot.org/uniprot/A0A0D5C501 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1580092:NADRNF5_RS08905 ^@ http://purl.uniprot.org/uniprot/A0A0D5C419 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS08475 ^@ http://purl.uniprot.org/uniprot/A0A0D5C528 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS01865 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0H5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/1580092:NADRNF5_RS03145 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1U3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the archaeal DnaG primase family.|||Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. http://togogenome.org/gene/1580092:NADRNF5_RS00500 ^@ http://purl.uniprot.org/uniprot/A0A0D5C081 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS10115 ^@ http://purl.uniprot.org/uniprot/A0A0D5C607 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/1580092:NADRNF5_RS00025 ^@ http://purl.uniprot.org/uniprot/A0A0D5BYT1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/1580092:NADRNF5_RS00690 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZH1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS03190 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0X4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||Involved in both the arginine and lysine biosynthetic pathways.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS08435 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4Y2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 2 subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS05110 ^@ http://purl.uniprot.org/uniprot/A0A0D5C337 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS25 family. http://togogenome.org/gene/1580092:NADRNF5_RS05210 ^@ http://purl.uniprot.org/uniprot/A0A0D5C365 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1580092:NADRNF5_RS08320 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3Q4 ^@ Function ^@ Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate. http://togogenome.org/gene/1580092:NADRNF5_RS01355 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0P1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the aTrm56 family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs. http://togogenome.org/gene/1580092:NADRNF5_RS04170 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1F7 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/1580092:NADRNF5_RS07500 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3F0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS10445 ^@ http://purl.uniprot.org/uniprot/A0A0D5C673 ^@ Function|||Similarity ^@ Belongs to the GrpE family.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/1580092:NADRNF5_RS01925 ^@ http://purl.uniprot.org/uniprot/A0A0D5C047 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1580092:NADRNF5_RS05560 ^@ http://purl.uniprot.org/uniprot/A0A0D5C393 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic release factor 1 family.|||Cytoplasm|||Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.|||Heterodimer of two subunits, one of which binds GTP. http://togogenome.org/gene/1580092:NADRNF5_RS00455 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZR0 ^@ Similarity ^@ Belongs to the UPF0201 family. http://togogenome.org/gene/1580092:NADRNF5_RS09560 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4E0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS08505 ^@ http://purl.uniprot.org/uniprot/A0A0D5C435 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL32 family. http://togogenome.org/gene/1580092:NADRNF5_RS00055 ^@ http://purl.uniprot.org/uniprot/A0A0D5C058 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. Archaeal-type CbiT family.|||Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7. http://togogenome.org/gene/1580092:NADRNF5_RS03415 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0U5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/1580092:NADRNF5_RS07930 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4T6 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/1580092:NADRNF5_RS05635 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3A6 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1580092:NADRNF5_RS09575 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5L4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1580092:NADRNF5_RS06070 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3P1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS4 family. http://togogenome.org/gene/1580092:NADRNF5_RS09570 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4N0 ^@ Similarity ^@ Belongs to the MCM family. http://togogenome.org/gene/1580092:NADRNF5_RS09145 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5G9 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. http://togogenome.org/gene/1580092:NADRNF5_RS04330 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2M5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1580092:NADRNF5_RS08845 ^@ http://purl.uniprot.org/uniprot/A0A0D5C564 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS03950 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2F3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Archaeal flagellum|||Belongs to the archaeal flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella. http://togogenome.org/gene/1580092:NADRNF5_RS05930 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2J6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. HMG-CoA synthase family. http://togogenome.org/gene/1580092:NADRNF5_RS03205 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0Q5 ^@ Similarity ^@ Belongs to the RimK family. LysX subfamily. http://togogenome.org/gene/1580092:NADRNF5_RS02040 ^@ http://purl.uniprot.org/uniprot/A0A0D5C064 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/1580092:NADRNF5_RS10400 ^@ http://purl.uniprot.org/uniprot/A0A0D5C634 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/1580092:NADRNF5_RS10550 ^@ http://purl.uniprot.org/uniprot/A0A0D5C689 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STT3 family.|||Membrane http://togogenome.org/gene/1580092:NADRNF5_RS00395 ^@ http://purl.uniprot.org/uniprot/A0A0D5C034 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1580092:NADRNF5_RS10170 ^@ http://purl.uniprot.org/uniprot/A0A0D5C523 ^@ Similarity ^@ Belongs to the NAD synthetase family. http://togogenome.org/gene/1580092:NADRNF5_RS08315 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4G6 ^@ Function ^@ Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate. http://togogenome.org/gene/1580092:NADRNF5_RS03645 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0Y7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/1580092:NADRNF5_RS08860 ^@ http://purl.uniprot.org/uniprot/A0A0D5C569 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS01750 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZS0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. http://togogenome.org/gene/1580092:NADRNF5_RS00090 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZW1 ^@ Similarity ^@ Belongs to the sulfate adenylyltransferase family. http://togogenome.org/gene/1580092:NADRNF5_RS00955 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZC7 ^@ Function|||Similarity ^@ Belongs to the CDC6/cdc18 family.|||Involved in regulation of DNA replication. http://togogenome.org/gene/1580092:NADRNF5_RS05215 ^@ http://purl.uniprot.org/uniprot/A0A0D5C207 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/1580092:NADRNF5_RS03470 ^@ http://purl.uniprot.org/uniprot/A0A0D5C259 ^@ Similarity ^@ Belongs to the AAA ATPase family. CDC48 subfamily. http://togogenome.org/gene/1580092:NADRNF5_RS07695 ^@ http://purl.uniprot.org/uniprot/A0A0D5C444 ^@ Similarity ^@ Belongs to the UbiD family. http://togogenome.org/gene/1580092:NADRNF5_RS03690 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1M7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/1580092:NADRNF5_RS06575 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3T7 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. http://togogenome.org/gene/1580092:NADRNF5_RS01495 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0R8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1580092:NADRNF5_RS04765 ^@ http://purl.uniprot.org/uniprot/A0A0D5C278 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. http://togogenome.org/gene/1580092:NADRNF5_RS01655 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZZ4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1580092:NADRNF5_RS07700 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3E0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnC family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/1580092:NADRNF5_RS01245 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0V2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic/archaeal RNase P protein component 4 family.|||Binds 1 zinc ion per subunit.|||Consists of a catalytic RNA component and at least 4-5 protein subunits.|||Cytoplasm|||Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. http://togogenome.org/gene/1580092:NADRNF5_RS09390 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5H8 ^@ Similarity ^@ Belongs to the complex I 20 kDa subunit family. http://togogenome.org/gene/1580092:NADRNF5_RS09260 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4I3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/1580092:NADRNF5_RS04135 ^@ http://purl.uniprot.org/uniprot/A0A0D5C179 ^@ Similarity ^@ Belongs to the V-ATPase F subunit family. http://togogenome.org/gene/1580092:NADRNF5_RS03285 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1F6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the methylthiotransferase family. CDKAL1 subfamily.|||Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/1580092:NADRNF5_RS09320 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5H0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS08265 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4F7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.|||Binds 1 zinc ion per subunit.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1580092:NADRNF5_RS03955 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1B5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Archaeal flagellum|||Belongs to the archaeal flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella. http://togogenome.org/gene/1580092:NADRNF5_RS04645 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1I6 ^@ Similarity ^@ Belongs to the DNA photolyase family. http://togogenome.org/gene/1580092:NADRNF5_RS05610 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3A1 ^@ Function|||Similarity ^@ Belongs to the phosphohexose mutase family.|||Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. http://togogenome.org/gene/1580092:NADRNF5_RS05795 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2G9 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/1580092:NADRNF5_RS03365 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0T5 ^@ Similarity ^@ Belongs to the HerA family. http://togogenome.org/gene/1580092:NADRNF5_RS00520 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZD7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS08255 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3Z3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the prefoldin subunit beta family.|||Cytoplasm|||Heterohexamer of two alpha and four beta subunits.|||Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. http://togogenome.org/gene/1580092:NADRNF5_RS04220 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1G7 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/1580092:NADRNF5_RS09310 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5J1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS05235 ^@ http://purl.uniprot.org/uniprot/A0A0D5C392 ^@ Similarity ^@ Belongs to the anthranilate synthase component I family. http://togogenome.org/gene/1580092:NADRNF5_RS03400 ^@ http://purl.uniprot.org/uniprot/A0A0D5C113 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NadC/ModD family.|||Hexamer formed by 3 homodimers.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/1580092:NADRNF5_RS00770 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZY4 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. PoK subfamily.|||Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway. http://togogenome.org/gene/1580092:NADRNF5_RS00140 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZX2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS02655 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0I0 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/1580092:NADRNF5_RS06050 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2L8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic/archaeal RNase P protein component 1 family.|||Consists of a catalytic RNA component and at least 4-5 protein subunits.|||Cytoplasm|||Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. http://togogenome.org/gene/1580092:NADRNF5_RS09670 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4P7 ^@ Similarity ^@ Belongs to the archease family. http://togogenome.org/gene/1580092:NADRNF5_RS10540 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5R8 ^@ Similarity ^@ Belongs to the eIF-2-alpha family. http://togogenome.org/gene/1580092:NADRNF5_RS00080 ^@ http://purl.uniprot.org/uniprot/A0A0D5C063 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/1580092:NADRNF5_RS09190 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4X8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GHMP kinase family. Mevalonate kinase subfamily.|||Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS02000 ^@ http://purl.uniprot.org/uniprot/A0A0D5C114 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1580092:NADRNF5_RS04870 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2Z1 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1580092:NADRNF5_RS04910 ^@ http://purl.uniprot.org/uniprot/A0A0D5C302 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/1580092:NADRNF5_RS00370 ^@ http://purl.uniprot.org/uniprot/A0A0D5C027 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GGGP/HepGP synthase family. Group II subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. http://togogenome.org/gene/1580092:NADRNF5_RS07840 ^@ http://purl.uniprot.org/uniprot/A0A0D5C476 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19. http://togogenome.org/gene/1580092:NADRNF5_RS05640 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2W0 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1580092:NADRNF5_RS05060 ^@ http://purl.uniprot.org/uniprot/A0A0D5C328 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1580092:NADRNF5_RS10600 ^@ http://purl.uniprot.org/uniprot/A0A0D5C507 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic-type primase small subunit family.|||Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.|||Heterodimer of a small subunit (PriS) and a large subunit (PriL).|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/1580092:NADRNF5_RS07815 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4M7 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS31 family.|||Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1580092:NADRNF5_RS01375 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZU6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NAC-alpha family.|||Contacts the emerging nascent chain on the ribosome.|||Homodimer. Interacts with the ribosome. Binds ribosomal RNA. http://togogenome.org/gene/1580092:NADRNF5_RS08620 ^@ http://purl.uniprot.org/uniprot/A0A0D5C557 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1580092:NADRNF5_RS02380 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0D2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/1580092:NADRNF5_RS06825 ^@ http://purl.uniprot.org/uniprot/A0A0D5C320 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.|||Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.|||Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA. http://togogenome.org/gene/1580092:NADRNF5_RS03390 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0T9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS10510 ^@ http://purl.uniprot.org/uniprot/A0A0D5C653 ^@ Function|||Similarity ^@ Belongs to the CbiD family.|||Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. http://togogenome.org/gene/1580092:NADRNF5_RS00740 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZI1 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/1580092:NADRNF5_RS10330 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5N2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS07610 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4I7 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1580092:NADRNF5_RS02310 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0R2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the TOP6B family.|||Homodimer. Heterotetramer of two Top6A and two Top6B chains.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Relaxes both positive and negative superturns and exhibits a strong decatenase activity. http://togogenome.org/gene/1580092:NADRNF5_RS06190 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3R6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1580092:NADRNF5_RS01760 ^@ http://purl.uniprot.org/uniprot/A0A0D5C015 ^@ Similarity ^@ Belongs to the protein kinase superfamily. BUD32 family. http://togogenome.org/gene/1580092:NADRNF5_RS01695 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZR1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS08020 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4R1 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1580092:NADRNF5_RS00045 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZF4 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1580092:NADRNF5_RS02250 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1E2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1580092:NADRNF5_RS02290 ^@ http://purl.uniprot.org/uniprot/A0A0D5C033 ^@ Similarity ^@ Belongs to the eIF-2-beta/eIF-5 family. http://togogenome.org/gene/1580092:NADRNF5_RS06060 ^@ http://purl.uniprot.org/uniprot/A0A0D5C334 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges. http://togogenome.org/gene/1580092:NADRNF5_RS08820 ^@ http://purl.uniprot.org/uniprot/A0A0D5C559 ^@ Similarity ^@ Belongs to the TFIIB family. http://togogenome.org/gene/1580092:NADRNF5_RS09195 ^@ http://purl.uniprot.org/uniprot/A0A0D5C472 ^@ Similarity ^@ Belongs to the isopentenyl phosphate kinase family. http://togogenome.org/gene/1580092:NADRNF5_RS03795 ^@ http://purl.uniprot.org/uniprot/A0A0D5C117 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/1580092:NADRNF5_RS08380 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4X6 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1580092:NADRNF5_RS09020 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4E2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds at least 2 Zn(2+) per subunit.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/1580092:NADRNF5_RS08330 ^@ http://purl.uniprot.org/uniprot/A0A0D5C406 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1580092:NADRNF5_RS04850 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2Y6 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.|||Belongs to the histone-like Alba family.|||Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.|||Chromosome|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1580092:NADRNF5_RS01765 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0X1 ^@ Similarity ^@ Belongs to the HAM1 NTPase family. http://togogenome.org/gene/1580092:NADRNF5_RS04830 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2X9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal NMN adenylyltransferase family.|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS01265 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZI3 ^@ Similarity ^@ Belongs to the PDCD5 family. http://togogenome.org/gene/1580092:NADRNF5_RS01640 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0E0 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/1580092:NADRNF5_RS01580 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0T6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CSL4 family.|||Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.|||Cytoplasm|||Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. http://togogenome.org/gene/1580092:NADRNF5_RS08445 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3S9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal adenylate kinase family.|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS04190 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2K2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.|||Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.|||Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS00440 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0E8 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ A single active site specifically recognizes both ATP and CTP and is responsible for their addition.|||Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.|||Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS08455 ^@ http://purl.uniprot.org/uniprot/A0A0D5C427 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1580092:NADRNF5_RS08300 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4Z9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1580092:NADRNF5_RS00470 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZC6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase Z family.|||Binds 2 Zn(2+) ions.|||Homodimer.|||Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. http://togogenome.org/gene/1580092:NADRNF5_RS01130 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0K1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Membrane http://togogenome.org/gene/1580092:NADRNF5_RS05655 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2E4 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1580092:NADRNF5_RS05540 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2U1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS03725 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2A9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/1580092:NADRNF5_RS04160 ^@ http://purl.uniprot.org/uniprot/A0A0D5C183 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1580092:NADRNF5_RS01035 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0R0 ^@ Similarity ^@ Belongs to the glutaredoxin family. http://togogenome.org/gene/1580092:NADRNF5_RS00985 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0Q2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS06075 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2M3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL5 family. http://togogenome.org/gene/1580092:NADRNF5_RS04230 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1X6 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1580092:NADRNF5_RS09715 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5R7 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1580092:NADRNF5_RS08185 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4T9 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/1580092:NADRNF5_RS03015 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1R8 ^@ Similarity|||Subunit ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family.|||Homohexamer. http://togogenome.org/gene/1580092:NADRNF5_RS08735 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4N3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1580092:NADRNF5_RS00855 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0F1 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS09030 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4U6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/1580092:NADRNF5_RS00765 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0D5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the archaeal phosphopantothenate synthetase family.|||Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.|||Homodimer. http://togogenome.org/gene/1580092:NADRNF5_RS07210 ^@ http://purl.uniprot.org/uniprot/A0A0D5C468 ^@ Similarity ^@ Belongs to the UPF0215 family. http://togogenome.org/gene/1580092:NADRNF5_RS07475 ^@ http://purl.uniprot.org/uniprot/A0A0D5C363 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1580092:NADRNF5_RS07665 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4P0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS09375 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4K0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS01350 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZU2 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the TFE family.|||Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.|||The winged helix domain is involved in binding to DNA in the preinitiation complex.|||Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes. http://togogenome.org/gene/1580092:NADRNF5_RS05895 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2A4 ^@ Similarity ^@ Belongs to the ATPase gamma chain family. http://togogenome.org/gene/1580092:NADRNF5_RS05290 ^@ http://purl.uniprot.org/uniprot/A0A0D5C269 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/1580092:NADRNF5_RS06055 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3I1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1580092:NADRNF5_RS00845 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0M4 ^@ Caution|||Similarity ^@ Belongs to the thymidylate kinase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS00700 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal NMN adenylyltransferase family.|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS09230 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4I0 ^@ Similarity ^@ Belongs to the UPF0147 family. http://togogenome.org/gene/1580092:NADRNF5_RS07160 ^@ http://purl.uniprot.org/uniprot/A0A0D5C457 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis. http://togogenome.org/gene/1580092:NADRNF5_RS09600 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4N5 ^@ Function|||Similarity ^@ Belongs to the eIF-6 family.|||Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. http://togogenome.org/gene/1580092:NADRNF5_RS08060 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4V8 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1580092:NADRNF5_RS04835 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1T3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS02970 ^@ http://purl.uniprot.org/uniprot/A0A0D5C193 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1580092:NADRNF5_RS05955 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3G4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS10380 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5P2 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/1580092:NADRNF5_RS10470 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5Q4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS00240 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZZ2 ^@ Function|||Similarity ^@ Belongs to the TFIIB family.|||Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). http://togogenome.org/gene/1580092:NADRNF5_RS03215 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0X9 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS01300 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZT6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer. http://togogenome.org/gene/1580092:NADRNF5_RS01190 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZG9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS01595 ^@ http://purl.uniprot.org/uniprot/A0A0D5C119 ^@ Function|||Similarity ^@ Belongs to the DPH1/DPH2 family.|||Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). http://togogenome.org/gene/1580092:NADRNF5_RS03705 ^@ http://purl.uniprot.org/uniprot/A0A0D5C166 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Dps family.|||Homododecamer. The 12 identical subunits form a hollow sphere into which the mineral iron core of up to 300 Fe(3+) can be deposited.|||Protects DNA from oxidative damage by sequestering intracellular Fe2+ ion and storing it in the form of Fe3+ oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe2+ ions, which prevents hydroxyl radical production by the Fenton reaction.|||nucleoid http://togogenome.org/gene/1580092:NADRNF5_RS08995 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5A4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NusA family.|||Cytoplasm|||Participates in transcription termination. http://togogenome.org/gene/1580092:NADRNF5_RS01630 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZY6 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. http://togogenome.org/gene/1580092:NADRNF5_RS06895 ^@ http://purl.uniprot.org/uniprot/A0A0D5C333 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS09710 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4G7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Cytoplasm|||Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.|||Part of the 50S ribosomal subunit. Probably part of the RNase P complex. http://togogenome.org/gene/1580092:NADRNF5_RS01825 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZT3 ^@ Function|||Similarity ^@ Belongs to the TBP family.|||General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. http://togogenome.org/gene/1580092:NADRNF5_RS07850 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4R9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eIF-5A family.|||Cytoplasm|||Functions by promoting the formation of the first peptide bond. http://togogenome.org/gene/1580092:NADRNF5_RS03715 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1N2 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/1580092:NADRNF5_RS08290 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4G2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the RNA polymerase complex. http://togogenome.org/gene/1580092:NADRNF5_RS01860 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0Y8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS1 family. http://togogenome.org/gene/1580092:NADRNF5_RS06085 ^@ http://purl.uniprot.org/uniprot/A0A0D5C338 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1580092:NADRNF5_RS04855 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1T7 ^@ Function|||Similarity ^@ Belongs to the TFIIB family.|||Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). http://togogenome.org/gene/1580092:NADRNF5_RS08740 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3Y9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1580092:NADRNF5_RS01635 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0U6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS09355 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5H4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/1580092:NADRNF5_RS02740 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0J8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS07465 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4C7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS08275 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4Z5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase PH family. Rrp41 subfamily.|||Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.|||Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS01525 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0S4 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/1580092:NADRNF5_RS06950 ^@ http://purl.uniprot.org/uniprot/A0A0D5C416 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS03385 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1H6 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the L-aspartate dehydrogenase family.|||Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.|||The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia. http://togogenome.org/gene/1580092:NADRNF5_RS01500 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0B7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/1580092:NADRNF5_RS00295 ^@ http://purl.uniprot.org/uniprot/A0A0D5C009 ^@ Similarity ^@ Belongs to the AAA ATPase family. CDC48 subfamily. http://togogenome.org/gene/1580092:NADRNF5_RS09360 ^@ http://purl.uniprot.org/uniprot/A0A0D5C504 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS00575 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZT5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PCNA family.|||Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.|||Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.|||Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication. http://togogenome.org/gene/1580092:NADRNF5_RS04560 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2K4 ^@ Function|||Similarity ^@ Belongs to the TFIIB family.|||Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). http://togogenome.org/gene/1580092:NADRNF5_RS01515 ^@ http://purl.uniprot.org/uniprot/A0A0D5C104 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL42 family.|||Binds 1 zinc ion per subunit.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1580092:NADRNF5_RS05950 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2K0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.|||Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS02410 ^@ http://purl.uniprot.org/uniprot/A0A0D5C196 ^@ Cofactor ^@ Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/1580092:NADRNF5_RS01310 ^@ http://purl.uniprot.org/uniprot/A0A0D5C080 ^@ Function|||Similarity ^@ Belongs to the archaeal-type GTP cyclohydrolase family.|||Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity. http://togogenome.org/gene/1580092:NADRNF5_RS01065 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0I7 ^@ Similarity ^@ Belongs to the glutaredoxin family. http://togogenome.org/gene/1580092:NADRNF5_RS08485 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4Z3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the prefoldin alpha subunit family.|||Belongs to the prefoldin subunit alpha family.|||Cytoplasm|||Heterohexamer of two alpha and four beta subunits.|||Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. http://togogenome.org/gene/1580092:NADRNF5_RS08525 ^@ http://purl.uniprot.org/uniprot/A0A0D5C539 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS08990 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4D8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Part of the 30S ribosomal subunit.|||With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. http://togogenome.org/gene/1580092:NADRNF5_RS02450 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0E5 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. http://togogenome.org/gene/1580092:NADRNF5_RS04925 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2B6 ^@ Similarity ^@ Belongs to the DNA polymerase type-B family. http://togogenome.org/gene/1580092:NADRNF5_RS02195 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0N6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal histone HMF family.|||Chromosome|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS08035 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4V1 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/1580092:NADRNF5_RS06385 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3V8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/1580092:NADRNF5_RS01320 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0W7 ^@ Similarity|||Subunit ^@ Belongs to the HTP reductase family.|||Homodimer. http://togogenome.org/gene/1580092:NADRNF5_RS10405 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5P6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1580092:NADRNF5_RS10035 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5X3 ^@ Similarity ^@ Belongs to the cytochrome c oxidase subunit 2 family. http://togogenome.org/gene/1580092:NADRNF5_RS10020 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5V3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS09535 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4D4 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1580092:NADRNF5_RS00375 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZN0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the archaeal DNA polymerase II family.|||Heterodimer of a large subunit and a small subunit.|||Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. http://togogenome.org/gene/1580092:NADRNF5_RS03530 ^@ http://purl.uniprot.org/uniprot/A0A0D5C210 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1580092:NADRNF5_RS05010 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1W5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS09130 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5D6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1580092:NADRNF5_RS05120 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2W7 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/1580092:NADRNF5_RS01870 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZU7 ^@ Similarity ^@ Belongs to the CTAG/PCC1 family. http://togogenome.org/gene/1580092:NADRNF5_RS01115 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZF5 ^@ Similarity ^@ Belongs to the transcriptional regulatory CopG/NikR family. http://togogenome.org/gene/1580092:NADRNF5_RS00905 ^@ http://purl.uniprot.org/uniprot/A0A0D5C013 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Membrane http://togogenome.org/gene/1580092:NADRNF5_RS03160 ^@ http://purl.uniprot.org/uniprot/A0A0D5C209 ^@ Similarity ^@ Belongs to the diphthine synthase family. http://togogenome.org/gene/1580092:NADRNF5_RS09465 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4L2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS06600 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3D7 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/1580092:NADRNF5_RS05005 ^@ http://purl.uniprot.org/uniprot/A0A0D5C319 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS09185 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5E6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1580092:NADRNF5_RS04760 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2P1 ^@ Similarity ^@ Belongs to the adenosylhomocysteinase family. http://togogenome.org/gene/1580092:NADRNF5_RS05625 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3G0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.|||Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS10605 ^@ http://purl.uniprot.org/uniprot/A0A0D5C697 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic-type primase large subunit family.|||Binds 1 [4Fe-4S] cluster.|||Heterodimer of a small subunit (PriS) and a large subunit (PriL).|||Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. http://togogenome.org/gene/1580092:NADRNF5_RS08510 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4Z7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL19 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1580092:NADRNF5_RS00935 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0P3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the PyrI family.|||Binds 1 zinc ion per subunit.|||Contains catalytic and regulatory chains.|||Involved in allosteric regulation of aspartate carbamoyltransferase. http://togogenome.org/gene/1580092:NADRNF5_RS02055 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0L0 ^@ Similarity ^@ Belongs to the PdxS/SNZ family. http://togogenome.org/gene/1580092:NADRNF5_RS07125 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4A0 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/1580092:NADRNF5_RS10545 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4Z8 ^@ Function|||Similarity ^@ Belongs to the NOP10 family.|||Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. http://togogenome.org/gene/1580092:NADRNF5_RS10065 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4W9 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1580092:NADRNF5_RS08780 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4P1 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/1580092:NADRNF5_RS08070 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3V5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS10120 ^@ http://purl.uniprot.org/uniprot/A0A0D5C505 ^@ Similarity ^@ Belongs to the PGI/PMI family. http://togogenome.org/gene/1580092:NADRNF5_RS06175 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3K2 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/1580092:NADRNF5_RS05145 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1Z2 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/1580092:NADRNF5_RS00505 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZS6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS04745 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1K4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS08450 ^@ http://purl.uniprot.org/uniprot/A0A0D5C525 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1580092:NADRNF5_RS06045 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3N6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1580092:NADRNF5_RS04275 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1A9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1580092:NADRNF5_RS01055 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZE4 ^@ Similarity ^@ Belongs to the glutaredoxin family. http://togogenome.org/gene/1580092:NADRNF5_RS08280 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3Z9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RRP4 family.|||Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.|||Cytoplasm|||Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. http://togogenome.org/gene/1580092:NADRNF5_RS04335 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1J0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1580092:NADRNF5_RS05195 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2Y8 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS07260 ^@ http://purl.uniprot.org/uniprot/A0A0D5C322 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/1580092:NADRNF5_RS05565 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2U7 ^@ Similarity ^@ Belongs to the glutaredoxin family. http://togogenome.org/gene/1580092:NADRNF5_RS06080 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3I5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1580092:NADRNF5_RS08080 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4W2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS05805 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2Y9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS07810 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3Q3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS24 family. http://togogenome.org/gene/1580092:NADRNF5_RS10620 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5T3 ^@ Similarity ^@ Belongs to the prespore-cell-inducing factor family. http://togogenome.org/gene/1580092:NADRNF5_RS10315 ^@ http://purl.uniprot.org/uniprot/A0A0D5C650 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/1580092:NADRNF5_RS07005 ^@ http://purl.uniprot.org/uniprot/A0A0D5C425 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the THI4 family.|||Homooctamer; tetramer of dimers.|||Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS00485 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZ40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1580092:NADRNF5_RS04145 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1F2 ^@ Similarity ^@ Belongs to the DeoC/FbaB aldolase family. http://togogenome.org/gene/1580092:NADRNF5_RS02430 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1A1 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA. http://togogenome.org/gene/1580092:NADRNF5_RS10360 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5P0 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/1580092:NADRNF5_RS00760 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZI4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/1580092:NADRNF5_RS04915 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1U8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS02150 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0M8 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1580092:NADRNF5_RS00570 ^@ http://purl.uniprot.org/uniprot/A0A0D5C097 ^@ Similarity ^@ Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. http://togogenome.org/gene/1580092:NADRNF5_RS00415 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZ85 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1580092:NADRNF5_RS00960 ^@ http://purl.uniprot.org/uniprot/A0A0D5C0P8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS07705 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4P4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.|||Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.|||Homodecamer. http://togogenome.org/gene/1580092:NADRNF5_RS05885 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3E9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS09525 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5K5 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/1580092:NADRNF5_RS07960 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3T3 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/1580092:NADRNF5_RS00340 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZ69 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA polymerase delta/II small subunit family.|||Heterodimer of a large subunit and a small subunit.|||Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. http://togogenome.org/gene/1580092:NADRNF5_RS03460 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1J2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Membrane http://togogenome.org/gene/1580092:NADRNF5_RS10365 ^@ http://purl.uniprot.org/uniprot/A0A0D5C660 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/1580092:NADRNF5_RS01110 ^@ http://purl.uniprot.org/uniprot/A0A0D5C049 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Cell membrane|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS08270 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3P4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase PH family. Rrp42 subfamily.|||Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.|||Cytoplasm|||Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. http://togogenome.org/gene/1580092:NADRNF5_RS05140 ^@ http://purl.uniprot.org/uniprot/A0A0D5C348 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS01545 ^@ http://purl.uniprot.org/uniprot/A0A0D5C108 ^@ Function ^@ Catalyzes the synthesis of GMP from XMP. http://togogenome.org/gene/1580092:NADRNF5_RS09350 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4J6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS01620 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZP8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/1580092:NADRNF5_RS07015 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2X8 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. http://togogenome.org/gene/1580092:NADRNF5_RS03270 ^@ http://purl.uniprot.org/uniprot/A0A0D5C226 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL39 family. http://togogenome.org/gene/1580092:NADRNF5_RS09490 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4L6 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. http://togogenome.org/gene/1580092:NADRNF5_RS09625 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4N9 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family. http://togogenome.org/gene/1580092:NADRNF5_RS02085 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZY9 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/1580092:NADRNF5_RS03710 ^@ http://purl.uniprot.org/uniprot/A0A0D5C235 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1580092:NADRNF5_RS02440 ^@ http://purl.uniprot.org/uniprot/A0A0D5C061 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic RPB4 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.|||Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure. http://togogenome.org/gene/1580092:NADRNF5_RS06260 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3M0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS07910 ^@ http://purl.uniprot.org/uniprot/A0A0D5C3S3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS00380 ^@ http://purl.uniprot.org/uniprot/A0A0D5BYZ4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS01490 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZW5 ^@ Caution|||Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1580092:NADRNF5_RS08910 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5C0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS01260 ^@ http://purl.uniprot.org/uniprot/A0A0D5C071 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS19 family.|||May be involved in maturation of the 30S ribosomal subunit.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1580092:NADRNF5_RS08440 ^@ http://purl.uniprot.org/uniprot/A0A0D5C4I5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1580092:NADRNF5_RS09210 ^@ http://purl.uniprot.org/uniprot/A0A0D5C5F2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm http://togogenome.org/gene/1580092:NADRNF5_RS00155 ^@ http://purl.uniprot.org/uniprot/A0A0D5C076 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/1580092:NADRNF5_RS00050 ^@ http://purl.uniprot.org/uniprot/A0A0D5BYT6 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1580092:NADRNF5_RS01625 ^@ http://purl.uniprot.org/uniprot/A0A0D5C124 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1580092:NADRNF5_RS05205 ^@ http://purl.uniprot.org/uniprot/A0A0D5C1T9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/1580092:NADRNF5_RS05605 ^@ http://purl.uniprot.org/uniprot/A0A0D5C2D5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1580092:NADRNF5_RS00160 ^@ http://purl.uniprot.org/uniprot/A0A0D5BZ32 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.