http://togogenome.org/gene/1433513:D7D53_RS07615 ^@ http://purl.uniprot.org/uniprot/A0A387B218 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS09940 ^@ http://purl.uniprot.org/uniprot/A0A387B6G5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1433513:D7D53_RS09020 ^@ http://purl.uniprot.org/uniprot/A0A387B2Q5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/1433513:D7D53_RS07590 ^@ http://purl.uniprot.org/uniprot/A0A387B1N5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.|||Cytoplasm http://togogenome.org/gene/1433513:D7D53_RS04825 ^@ http://purl.uniprot.org/uniprot/A0A387B3M5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS01975 ^@ http://purl.uniprot.org/uniprot/A0A387B957 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/1433513:D7D53_RS06055 ^@ http://purl.uniprot.org/uniprot/A0A387B496 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1433513:D7D53_RS05080 ^@ http://purl.uniprot.org/uniprot/A0A387B0M4 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/1433513:D7D53_RS02395 ^@ http://purl.uniprot.org/uniprot/A0A387B299 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1433513:D7D53_RS09470 ^@ http://purl.uniprot.org/uniprot/A0A387B4L7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1433513:D7D53_RS03355 ^@ http://purl.uniprot.org/uniprot/A0A387AZU9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1433513:D7D53_RS03300 ^@ http://purl.uniprot.org/uniprot/A0A387AZX9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.|||Homohexamer; trimer of homodimers. http://togogenome.org/gene/1433513:D7D53_RS00060 ^@ http://purl.uniprot.org/uniprot/A0A387AY47 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/1433513:D7D53_RS07470 ^@ http://purl.uniprot.org/uniprot/A0A387B3N9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.|||Cell membrane|||Membrane|||Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. http://togogenome.org/gene/1433513:D7D53_RS09475 ^@ http://purl.uniprot.org/uniprot/A0A387AZN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1433513:D7D53_RS01770 ^@ http://purl.uniprot.org/uniprot/A0A387B0S7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1433513:D7D53_RS03115 ^@ http://purl.uniprot.org/uniprot/A0A387AWR8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the YabA family.|||Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.|||Involved in initiation control of chromosome replication. http://togogenome.org/gene/1433513:D7D53_RS00365 ^@ http://purl.uniprot.org/uniprot/A0A387AVP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VirD4/TraG family.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS06645 ^@ http://purl.uniprot.org/uniprot/A0A387B329 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1433513:D7D53_RS09145 ^@ http://purl.uniprot.org/uniprot/A0A387B5T8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1433513:D7D53_RS08390 ^@ http://purl.uniprot.org/uniprot/A0A387B2D9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 1 family.|||Cell membrane http://togogenome.org/gene/1433513:D7D53_RS07830 ^@ http://purl.uniprot.org/uniprot/A0A387B5U1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1433513:D7D53_RS09240 ^@ http://purl.uniprot.org/uniprot/A0A387B2U3 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/1433513:D7D53_RS01485 ^@ http://purl.uniprot.org/uniprot/A0A387AYS7 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/1433513:D7D53_RS00715 ^@ http://purl.uniprot.org/uniprot/A0A387AVS9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1433513:D7D53_RS07875 ^@ http://purl.uniprot.org/uniprot/A0A387B1U1 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/1433513:D7D53_RS07785 ^@ http://purl.uniprot.org/uniprot/A0A387B3N0 ^@ Function ^@ Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions. http://togogenome.org/gene/1433513:D7D53_RS09960 ^@ http://purl.uniprot.org/uniprot/A0A387B2V8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1433513:D7D53_RS00135 ^@ http://purl.uniprot.org/uniprot/A0A387B809 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS03960 ^@ http://purl.uniprot.org/uniprot/A0A387B1W4 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/1433513:D7D53_RS00395 ^@ http://purl.uniprot.org/uniprot/A0A387B867 ^@ Similarity ^@ Belongs to the UPF0236 family. http://togogenome.org/gene/1433513:D7D53_RS07870 ^@ http://purl.uniprot.org/uniprot/A0A387AZ08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS09915 ^@ http://purl.uniprot.org/uniprot/A0A387AZW5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/1433513:D7D53_RS09905 ^@ http://purl.uniprot.org/uniprot/A0A387AZV1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/1433513:D7D53_RS04945 ^@ http://purl.uniprot.org/uniprot/A0A387AXN4 ^@ Function|||Similarity ^@ Belongs to the UPF0122 family.|||Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. http://togogenome.org/gene/1433513:D7D53_RS08295 ^@ http://purl.uniprot.org/uniprot/A0A387BCV7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/1433513:D7D53_RS09225 ^@ http://purl.uniprot.org/uniprot/A0A387AZK6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/1433513:D7D53_RS02715 ^@ http://purl.uniprot.org/uniprot/A0A387B366 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/1433513:D7D53_RS03845 ^@ http://purl.uniprot.org/uniprot/A0A387BAC8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a set of proteins in which some residues (ACT_SITE, NP_BIND, REGION and BINDING) are not conserved. http://togogenome.org/gene/1433513:D7D53_RS07650 ^@ http://purl.uniprot.org/uniprot/A0A387AYX1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/1433513:D7D53_RS04880 ^@ http://purl.uniprot.org/uniprot/A0A387BAZ2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS07640 ^@ http://purl.uniprot.org/uniprot/A0A387AYX3 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/1433513:D7D53_RS08475 ^@ http://purl.uniprot.org/uniprot/A0A387AZ77 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1433513:D7D53_RS05955 ^@ http://purl.uniprot.org/uniprot/A0A387B123 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1433513:D7D53_RS05565 ^@ http://purl.uniprot.org/uniprot/A0A387B402 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1433513:D7D53_RS09930 ^@ http://purl.uniprot.org/uniprot/A0A387B349 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1433513:D7D53_RS01585 ^@ http://purl.uniprot.org/uniprot/A0A387B0P5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CobB/CobQ family. GatD subfamily.|||Forms a heterodimer with MurT.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT. http://togogenome.org/gene/1433513:D7D53_RS01655 ^@ http://purl.uniprot.org/uniprot/A0A387AW54 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/1433513:D7D53_RS05965 ^@ http://purl.uniprot.org/uniprot/A0A387B487 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1433513:D7D53_RS04690 ^@ http://purl.uniprot.org/uniprot/A0A387AXJ2 ^@ Similarity|||Subunit ^@ Belongs to the LacAB/RpiB family.|||Heteromultimeric protein consisting of LacA and LacB. http://togogenome.org/gene/1433513:D7D53_RS03520 ^@ http://purl.uniprot.org/uniprot/A0A387B3M8 ^@ Similarity ^@ Belongs to the thioester dehydratase family. FabZ subfamily. http://togogenome.org/gene/1433513:D7D53_RS04800 ^@ http://purl.uniprot.org/uniprot/A0A387AXK6 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by fructose 1,6-bisphosphate (FBP).|||Belongs to the LDH/MDH superfamily. LDH family.|||Catalyzes the conversion of lactate to pyruvate.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1433513:D7D53_RS02660 ^@ http://purl.uniprot.org/uniprot/A0A387B356 ^@ Function|||Similarity|||Subunit ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Homodimer and homohexamer; in equilibrium.|||Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. http://togogenome.org/gene/1433513:D7D53_RS09785 ^@ http://purl.uniprot.org/uniprot/A0A387B6C9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1433513:D7D53_RS09230 ^@ http://purl.uniprot.org/uniprot/A0A387B5X7 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1433513:D7D53_RS07475 ^@ http://purl.uniprot.org/uniprot/A0A387AYU7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm http://togogenome.org/gene/1433513:D7D53_RS04725 ^@ http://purl.uniprot.org/uniprot/A0A387B3K4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/1433513:D7D53_RS09835 ^@ http://purl.uniprot.org/uniprot/A0A387B4N5 ^@ Similarity ^@ Belongs to the UPF0297 family. http://togogenome.org/gene/1433513:D7D53_RS07160 ^@ http://purl.uniprot.org/uniprot/A0A387B5G6 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1433513:D7D53_RS08525 ^@ http://purl.uniprot.org/uniprot/A0A387AZ97 ^@ Similarity ^@ Belongs to the TelA family. http://togogenome.org/gene/1433513:D7D53_RS05430 ^@ http://purl.uniprot.org/uniprot/A0A387BB94 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArsC family. Spx subfamily.|||Cytoplasm|||Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.|||Interacts with the C-terminal domain of the alpha subunit of the RNAP. http://togogenome.org/gene/1433513:D7D53_RS05440 ^@ http://purl.uniprot.org/uniprot/A0A387AXW5 ^@ Function|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily. NagD family.|||Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro. http://togogenome.org/gene/1433513:D7D53_RS04400 ^@ http://purl.uniprot.org/uniprot/A0A387B239 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. http://togogenome.org/gene/1433513:D7D53_RS09220 ^@ http://purl.uniprot.org/uniprot/A0A387B2I4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1433513:D7D53_RS00085 ^@ http://purl.uniprot.org/uniprot/A0A387AVI6 ^@ Similarity|||Subunit ^@ Belongs to the UPF0237 family.|||Homodimer. http://togogenome.org/gene/1433513:D7D53_RS04705 ^@ http://purl.uniprot.org/uniprot/A0A387B3J3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1433513:D7D53_RS01505 ^@ http://purl.uniprot.org/uniprot/A0A387AYW8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1433513:D7D53_RS09385 ^@ http://purl.uniprot.org/uniprot/A0A387AZN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS09055 ^@ http://purl.uniprot.org/uniprot/A0A387AZG8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/1433513:D7D53_RS00045 ^@ http://purl.uniprot.org/uniprot/A0A387AVJ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1433513:D7D53_RS02935 ^@ http://purl.uniprot.org/uniprot/A0A387AZM7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1433513:D7D53_RS09430 ^@ http://purl.uniprot.org/uniprot/A0A387B2M4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1433513:D7D53_RS06350 ^@ http://purl.uniprot.org/uniprot/A0A387B2Y1 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1433513:D7D53_RS04740 ^@ http://purl.uniprot.org/uniprot/A0A387AXK4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/1433513:D7D53_RS07860 ^@ http://purl.uniprot.org/uniprot/A0A387B3W6 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1433513:D7D53_RS09825 ^@ http://purl.uniprot.org/uniprot/A0A387B6L8 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/1433513:D7D53_RS00185 ^@ http://purl.uniprot.org/uniprot/A0A387B157 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/1433513:D7D53_RS03345 ^@ http://purl.uniprot.org/uniprot/A0A387B2U1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS09070 ^@ http://purl.uniprot.org/uniprot/A0A387B2R3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/1433513:D7D53_RS07520 ^@ http://purl.uniprot.org/uniprot/A0A387BCI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1433513:D7D53_RS00960 ^@ http://purl.uniprot.org/uniprot/A0A387B8J4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS07425 ^@ http://purl.uniprot.org/uniprot/A0A387B1L5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1433513:D7D53_RS09910 ^@ http://purl.uniprot.org/uniprot/A0A387B2V0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1433513:D7D53_RS05750 ^@ http://purl.uniprot.org/uniprot/A0A387B2N3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PPase class C family.|||Binds 2 manganese ions per subunit.|||Cytoplasm http://togogenome.org/gene/1433513:D7D53_RS04650 ^@ http://purl.uniprot.org/uniprot/A0A387AXI0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/1433513:D7D53_RS09945 ^@ http://purl.uniprot.org/uniprot/A0A387BDW7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1433513:D7D53_RS00460 ^@ http://purl.uniprot.org/uniprot/A0A387AVP8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1433513:D7D53_RS05140 ^@ http://purl.uniprot.org/uniprot/A0A387B2B9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1433513:D7D53_RS04415 ^@ http://purl.uniprot.org/uniprot/A0A387AXE5 ^@ Similarity ^@ Belongs to the transposase 7 family. http://togogenome.org/gene/1433513:D7D53_RS04860 ^@ http://purl.uniprot.org/uniprot/A0A387B4C7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/1433513:D7D53_RS04785 ^@ http://purl.uniprot.org/uniprot/A0A387B297 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1433513:D7D53_RS04695 ^@ http://purl.uniprot.org/uniprot/A0A387B0A9 ^@ Similarity|||Subunit ^@ Belongs to the LacAB/RpiB family.|||Heteromultimeric protein consisting of LacA and LacB. http://togogenome.org/gene/1433513:D7D53_RS01615 ^@ http://purl.uniprot.org/uniprot/A0A387B1W9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CodY family.|||Cytoplasm|||DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor. http://togogenome.org/gene/1433513:D7D53_RS08890 ^@ http://purl.uniprot.org/uniprot/A0A387B4B8 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1433513:D7D53_RS05365 ^@ http://purl.uniprot.org/uniprot/A0A387B2F5 ^@ Similarity ^@ Belongs to the alpha-acetolactate decarboxylase family. http://togogenome.org/gene/1433513:D7D53_RS04855 ^@ http://purl.uniprot.org/uniprot/A0A387B3M3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1433513:D7D53_RS02065 ^@ http://purl.uniprot.org/uniprot/A0A387AWD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EsaA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1433513:D7D53_RS00015 ^@ http://purl.uniprot.org/uniprot/A0A387B128 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1433513:D7D53_RS09410 ^@ http://purl.uniprot.org/uniprot/A0A387B656 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.|||Belongs to the DltC family.|||Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.|||Cytoplasm http://togogenome.org/gene/1433513:D7D53_RS08745 ^@ http://purl.uniprot.org/uniprot/A0A387B281 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1433513:D7D53_RS00225 ^@ http://purl.uniprot.org/uniprot/A0A387B1W2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family. YeeN subfamily.|||Cytoplasm http://togogenome.org/gene/1433513:D7D53_RS09935 ^@ http://purl.uniprot.org/uniprot/A0A387B4Q7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1433513:D7D53_RS00475 ^@ http://purl.uniprot.org/uniprot/A0A387B191 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1433513:D7D53_RS08895 ^@ http://purl.uniprot.org/uniprot/A0A387AZF2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/1433513:D7D53_RS03860 ^@ http://purl.uniprot.org/uniprot/A0A387AZX6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1433513:D7D53_RS07835 ^@ http://purl.uniprot.org/uniprot/A0A387B253 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homodimer.|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport. http://togogenome.org/gene/1433513:D7D53_RS08335 ^@ http://purl.uniprot.org/uniprot/A0A387B5Z8 ^@ Function ^@ Required for transformation and DNA binding. http://togogenome.org/gene/1433513:D7D53_RS07840 ^@ http://purl.uniprot.org/uniprot/A0A387B3P0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1433513:D7D53_RS03310 ^@ http://purl.uniprot.org/uniprot/A0A387B1G1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/1433513:D7D53_RS07610 ^@ http://purl.uniprot.org/uniprot/A0A387B5Q2 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/1433513:D7D53_RS00815 ^@ http://purl.uniprot.org/uniprot/A0A387AVU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1433513:D7D53_RS09315 ^@ http://purl.uniprot.org/uniprot/A0A387BDE3 ^@ Similarity ^@ Belongs to the CtsR family. http://togogenome.org/gene/1433513:D7D53_RS00025 ^@ http://purl.uniprot.org/uniprot/A0A387AZX3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1433513:D7D53_RS06130 ^@ http://purl.uniprot.org/uniprot/A0A387B151 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/1433513:D7D53_RS03730 ^@ http://purl.uniprot.org/uniprot/A0A387B007 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1433513:D7D53_RS09205 ^@ http://purl.uniprot.org/uniprot/A0A387B4H1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS09200 ^@ http://purl.uniprot.org/uniprot/A0A387BDC4 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/1433513:D7D53_RS09920 ^@ http://purl.uniprot.org/uniprot/A0A387B6A4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1433513:D7D53_RS03950 ^@ http://purl.uniprot.org/uniprot/A0A387B357 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1433513:D7D53_RS02790 ^@ http://purl.uniprot.org/uniprot/A0A387B9M3 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/1433513:D7D53_RS00795 ^@ http://purl.uniprot.org/uniprot/A0A387B006 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1433513:D7D53_RS05400 ^@ http://purl.uniprot.org/uniprot/A0A387AXV8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS00040 ^@ http://purl.uniprot.org/uniprot/A0A387AY31 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1433513:D7D53_RS00920 ^@ http://purl.uniprot.org/uniprot/A0A387AVV0 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/1433513:D7D53_RS06820 ^@ http://purl.uniprot.org/uniprot/A0A387B3D7 ^@ Function|||Similarity ^@ Belongs to the QueH family.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). http://togogenome.org/gene/1433513:D7D53_RS04670 ^@ http://purl.uniprot.org/uniprot/A0A387B236 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1433513:D7D53_RS02910 ^@ http://purl.uniprot.org/uniprot/A0A387AWN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. Ycf16 family.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS02310 ^@ http://purl.uniprot.org/uniprot/A0A387B275 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. http://togogenome.org/gene/1433513:D7D53_RS02420 ^@ http://purl.uniprot.org/uniprot/A0A387B9D9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1433513:D7D53_RS03130 ^@ http://purl.uniprot.org/uniprot/A0A387B2Q6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmG family. TrmFO subfamily.|||Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.|||Cytoplasm http://togogenome.org/gene/1433513:D7D53_RS04260 ^@ http://purl.uniprot.org/uniprot/A0A387B090 ^@ Similarity ^@ Belongs to the agmatine deiminase family. http://togogenome.org/gene/1433513:D7D53_RS04755 ^@ http://purl.uniprot.org/uniprot/A0A387B3K3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1433513:D7D53_RS00050 ^@ http://purl.uniprot.org/uniprot/A0A387B107 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1433513:D7D53_RS06325 ^@ http://purl.uniprot.org/uniprot/A0A387B6F2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1433513:D7D53_RS04590 ^@ http://purl.uniprot.org/uniprot/A0A387B089 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1433513:D7D53_RS09895 ^@ http://purl.uniprot.org/uniprot/A0A387BDV9 ^@ Function|||Similarity ^@ Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/1433513:D7D53_RS06940 ^@ http://purl.uniprot.org/uniprot/A0A387B4P0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/1433513:D7D53_RS05025 ^@ http://purl.uniprot.org/uniprot/A0A387B0L7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/1433513:D7D53_RS01105 ^@ http://purl.uniprot.org/uniprot/A0A387AYP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1433513:D7D53_RS00890 ^@ http://purl.uniprot.org/uniprot/A0A387B2A1 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1433513:D7D53_RS08750 ^@ http://purl.uniprot.org/uniprot/A0A387AZC2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1433513:D7D53_RS03185 ^@ http://purl.uniprot.org/uniprot/A0A387B2R6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1433513:D7D53_RS07515 ^@ http://purl.uniprot.org/uniprot/A0A387B511 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily.|||Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. http://togogenome.org/gene/1433513:D7D53_RS03445 ^@ http://purl.uniprot.org/uniprot/A0A387AX01 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/1433513:D7D53_RS02375 ^@ http://purl.uniprot.org/uniprot/A0A387B114 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1433513:D7D53_RS05790 ^@ http://purl.uniprot.org/uniprot/A0A387B442 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/1433513:D7D53_RS09155 ^@ http://purl.uniprot.org/uniprot/A0A387B4F7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/1433513:D7D53_RS07135 ^@ http://purl.uniprot.org/uniprot/A0A387AYP3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/1433513:D7D53_RS00485 ^@ http://purl.uniprot.org/uniprot/A0A387AYB7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.|||Homotetramer. http://togogenome.org/gene/1433513:D7D53_RS08825 ^@ http://purl.uniprot.org/uniprot/A0A387B5N2 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1433513:D7D53_RS07800 ^@ http://purl.uniprot.org/uniprot/A0A387B3V4 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/1433513:D7D53_RS04275 ^@ http://purl.uniprot.org/uniprot/A0A387BAL7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1433513:D7D53_RS01970 ^@ http://purl.uniprot.org/uniprot/A0A387B221 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/1433513:D7D53_RS01390 ^@ http://purl.uniprot.org/uniprot/A0A387AYU6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1433513:D7D53_RS07140 ^@ http://purl.uniprot.org/uniprot/A0A387B1G8 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/1433513:D7D53_RS08045 ^@ http://purl.uniprot.org/uniprot/A0A387B596 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1433513:D7D53_RS00195 ^@ http://purl.uniprot.org/uniprot/A0A387B818 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/1433513:D7D53_RS03060 ^@ http://purl.uniprot.org/uniprot/A0A387B1D0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/1433513:D7D53_RS00940 ^@ http://purl.uniprot.org/uniprot/A0A387B2B0 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1433513:D7D53_RS02805 ^@ http://purl.uniprot.org/uniprot/A0A387AZE6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1433513:D7D53_RS09690 ^@ http://purl.uniprot.org/uniprot/A0A387B4Q2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1433513:D7D53_RS09900 ^@ http://purl.uniprot.org/uniprot/A0A387B4T7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1433513:D7D53_RS04810 ^@ http://purl.uniprot.org/uniprot/A0A387B4B6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS04765 ^@ http://purl.uniprot.org/uniprot/A0A387B0H2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/1433513:D7D53_RS08400 ^@ http://purl.uniprot.org/uniprot/A0A387B5E7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1433513:D7D53_RS01515 ^@ http://purl.uniprot.org/uniprot/A0A387B1U2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1433513:D7D53_RS05675 ^@ http://purl.uniprot.org/uniprot/A0A387B0S5 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/1433513:D7D53_RS09950 ^@ http://purl.uniprot.org/uniprot/A0A387B4U7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1433513:D7D53_RS04850 ^@ http://purl.uniprot.org/uniprot/A0A387AXL5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/1433513:D7D53_RS00925 ^@ http://purl.uniprot.org/uniprot/A0A387AYI9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/1433513:D7D53_RS02755 ^@ http://purl.uniprot.org/uniprot/A0A387AZD5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1433513:D7D53_RS08965 ^@ http://purl.uniprot.org/uniprot/A0A387BE87 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1433513:D7D53_RS03650 ^@ http://purl.uniprot.org/uniprot/A0A387AX35 ^@ Function|||Similarity ^@ Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.|||Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. http://togogenome.org/gene/1433513:D7D53_RS04410 ^@ http://purl.uniprot.org/uniprot/A0A387B063 ^@ Similarity ^@ Belongs to the site-specific recombinase resolvase family. http://togogenome.org/gene/1433513:D7D53_RS04870 ^@ http://purl.uniprot.org/uniprot/A0A387B272 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS00915 ^@ http://purl.uniprot.org/uniprot/A0A387B0D5 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/1433513:D7D53_RS01020 ^@ http://purl.uniprot.org/uniprot/A0A387B0F3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/1433513:D7D53_RS08210 ^@ http://purl.uniprot.org/uniprot/A0A387B5C1 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/1433513:D7D53_RS06275 ^@ http://purl.uniprot.org/uniprot/A0A387AY98 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/1433513:D7D53_RS05110 ^@ http://purl.uniprot.org/uniprot/A0A387AXR0 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/1433513:D7D53_RS00075 ^@ http://purl.uniprot.org/uniprot/A0A387B7Z9 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1433513:D7D53_RS07620 ^@ http://purl.uniprot.org/uniprot/A0A387B3K0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.|||Belongs to the organic radical-activating enzymes family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm http://togogenome.org/gene/1433513:D7D53_RS00020 ^@ http://purl.uniprot.org/uniprot/A0A387B7Y5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1433513:D7D53_RS09745 ^@ http://purl.uniprot.org/uniprot/A0A387AZS5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/1433513:D7D53_RS01605 ^@ http://purl.uniprot.org/uniprot/A0A387AW58 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DEAD box helicase family. CshA subfamily.|||Cytoplasm|||DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.|||Oligomerizes, may be a member of the RNA degradosome. http://togogenome.org/gene/1433513:D7D53_RS05385 ^@ http://purl.uniprot.org/uniprot/A0A387B2K0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/1433513:D7D53_RS02415 ^@ http://purl.uniprot.org/uniprot/A0A387B2A2 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/1433513:D7D53_RS06215 ^@ http://purl.uniprot.org/uniprot/A0A387AY88 ^@ Function|||Similarity ^@ Belongs to the NanE family.|||Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P). http://togogenome.org/gene/1433513:D7D53_RS08255 ^@ http://purl.uniprot.org/uniprot/A0A387B1Y2 ^@ Similarity ^@ In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.|||In the N-terminal section; belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1433513:D7D53_RS09600 ^@ http://purl.uniprot.org/uniprot/A0A387B639 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/1433513:D7D53_RS06360 ^@ http://purl.uniprot.org/uniprot/A0A387BBQ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm http://togogenome.org/gene/1433513:D7D53_RS04660 ^@ http://purl.uniprot.org/uniprot/A0A387B484 ^@ Function|||Similarity ^@ Belongs to the ArsC family.|||Belongs to the glutaredoxin family.|||Electron transport system for the ribonucleotide reductase system NrdEF. http://togogenome.org/gene/1433513:D7D53_RS05030 ^@ http://purl.uniprot.org/uniprot/A0A387B2A0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/1433513:D7D53_RS07220 ^@ http://purl.uniprot.org/uniprot/A0A387B3C4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/1433513:D7D53_RS01995 ^@ http://purl.uniprot.org/uniprot/A0A387AZ19 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/1433513:D7D53_RS02430 ^@ http://purl.uniprot.org/uniprot/A0A387AWG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0291 family.|||Cytoplasm http://togogenome.org/gene/1433513:D7D53_RS00710 ^@ http://purl.uniprot.org/uniprot/A0A387B098 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/1433513:D7D53_RS02080 ^@ http://purl.uniprot.org/uniprot/A0A387AZ65 ^@ Similarity ^@ Belongs to the EssB family. http://togogenome.org/gene/1433513:D7D53_RS03870 ^@ http://purl.uniprot.org/uniprot/A0A387B337 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/1433513:D7D53_RS04655 ^@ http://purl.uniprot.org/uniprot/A0A387B3I2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HPr family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.|||P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity. http://togogenome.org/gene/1433513:D7D53_RS02670 ^@ http://purl.uniprot.org/uniprot/A0A387B143 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/1433513:D7D53_RS09180 ^@ http://purl.uniprot.org/uniprot/A0A387B6D8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane|||This protein catalyzes the committed step to the synthesis of the acidic phospholipids. http://togogenome.org/gene/1433513:D7D53_RS06110 ^@ http://purl.uniprot.org/uniprot/A0A387B0Z9 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/1433513:D7D53_RS09295 ^@ http://purl.uniprot.org/uniprot/A0A387B314 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/1433513:D7D53_RS00005 ^@ http://purl.uniprot.org/uniprot/A0A387AY39 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/1433513:D7D53_RS00805 ^@ http://purl.uniprot.org/uniprot/A0A387B8G0 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1433513:D7D53_RS07290 ^@ http://purl.uniprot.org/uniprot/A0A387AYR9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/1433513:D7D53_RS05960 ^@ http://purl.uniprot.org/uniprot/A0A387B2S3 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/1433513:D7D53_RS06115 ^@ http://purl.uniprot.org/uniprot/A0A387AY69 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/1433513:D7D53_RS01920 ^@ http://purl.uniprot.org/uniprot/A0A387B946 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1433513:D7D53_RS03070 ^@ http://purl.uniprot.org/uniprot/A0A387AZJ4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1433513:D7D53_RS00030 ^@ http://purl.uniprot.org/uniprot/A0A387AZX4 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1433513:D7D53_RS06070 ^@ http://purl.uniprot.org/uniprot/A0A387B141 ^@ Function|||Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/1433513:D7D53_RS01665 ^@ http://purl.uniprot.org/uniprot/A0A387AW66 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/1433513:D7D53_RS05735 ^@ http://purl.uniprot.org/uniprot/A0A387B433 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/1433513:D7D53_RS09060 ^@ http://purl.uniprot.org/uniprot/A0A387B5U2 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/1433513:D7D53_RS00470 ^@ http://purl.uniprot.org/uniprot/A0A387AVQ8 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1433513:D7D53_RS00865 ^@ http://purl.uniprot.org/uniprot/A0A387B0C6 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1433513:D7D53_RS06500 ^@ http://purl.uniprot.org/uniprot/A0A387AYD9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1433513:D7D53_RS04145 ^@ http://purl.uniprot.org/uniprot/A0A387B391 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/1433513:D7D53_RS08740 ^@ http://purl.uniprot.org/uniprot/A0A387AZC7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1433513:D7D53_RS08235 ^@ http://purl.uniprot.org/uniprot/A0A387BCU6 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1433513:D7D53_RS02335 ^@ http://purl.uniprot.org/uniprot/A0A387AZ63 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/1433513:D7D53_RS08220 ^@ http://purl.uniprot.org/uniprot/A0A387B2A4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1433513:D7D53_RS03135 ^@ http://purl.uniprot.org/uniprot/A0A387B3F4 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1433513:D7D53_RS02070 ^@ http://purl.uniprot.org/uniprot/A0A387B241 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EssA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1433513:D7D53_RS06830 ^@ http://purl.uniprot.org/uniprot/A0A387B1A6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1433513:D7D53_RS02950 ^@ http://purl.uniprot.org/uniprot/A0A387B9Q8 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1433513:D7D53_RS01215 ^@ http://purl.uniprot.org/uniprot/A0A387B2F8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1433513:D7D53_RS02060 ^@ http://purl.uniprot.org/uniprot/A0A387AZ26 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/1433513:D7D53_RS06965 ^@ http://purl.uniprot.org/uniprot/A0A387BC71 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/1433513:D7D53_RS07525 ^@ http://purl.uniprot.org/uniprot/A0A387B3P8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1433513:D7D53_RS07260 ^@ http://purl.uniprot.org/uniprot/A0A387B5I7 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/1433513:D7D53_RS05135 ^@ http://purl.uniprot.org/uniprot/A0A387B0N4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/1433513:D7D53_RS08465 ^@ http://purl.uniprot.org/uniprot/A0A387AZ87 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1433513:D7D53_RS07450 ^@ http://purl.uniprot.org/uniprot/A0A387B001 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1433513:D7D53_RS08120 ^@ http://purl.uniprot.org/uniprot/A0A387AZ38 ^@ Function|||Similarity ^@ Belongs to the transferase hexapeptide repeat family. DapH subfamily.|||Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. http://togogenome.org/gene/1433513:D7D53_RS07130 ^@ http://purl.uniprot.org/uniprot/A0A387B3J2 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1433513:D7D53_RS05345 ^@ http://purl.uniprot.org/uniprot/A0A387AXU9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1433513:D7D53_RS09495 ^@ http://purl.uniprot.org/uniprot/A0A387B6H3 ^@ Function|||Similarity ^@ Belongs to the TrhO family.|||Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs. http://togogenome.org/gene/1433513:D7D53_RS01060 ^@ http://purl.uniprot.org/uniprot/A0A387B1L7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ThrE exporter (TC 2.A.79) family.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS07755 ^@ http://purl.uniprot.org/uniprot/A0A387B1S2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/1433513:D7D53_RS05840 ^@ http://purl.uniprot.org/uniprot/A0A387B455 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1433513:D7D53_RS01025 ^@ http://purl.uniprot.org/uniprot/A0A387AVW0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1433513:D7D53_RS09800 ^@ http://purl.uniprot.org/uniprot/A0A387AZT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS09635 ^@ http://purl.uniprot.org/uniprot/A0A387AZQ9 ^@ Similarity ^@ Belongs to the UPF0177 family. http://togogenome.org/gene/1433513:D7D53_RS07900 ^@ http://purl.uniprot.org/uniprot/A0A387B3Q0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/1433513:D7D53_RS03340 ^@ http://purl.uniprot.org/uniprot/A0A387AWY2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1433513:D7D53_RS01540 ^@ http://purl.uniprot.org/uniprot/A0A387AYT8 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/1433513:D7D53_RS04515 ^@ http://purl.uniprot.org/uniprot/A0A387B209 ^@ Similarity ^@ Belongs to the zeta toxin family. http://togogenome.org/gene/1433513:D7D53_RS01845 ^@ http://purl.uniprot.org/uniprot/A0A387B203 ^@ Similarity|||Subunit ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.|||Homotetramer. http://togogenome.org/gene/1433513:D7D53_RS04360 ^@ http://purl.uniprot.org/uniprot/A0A387B3D0 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1433513:D7D53_RS08585 ^@ http://purl.uniprot.org/uniprot/A0A387B248 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1433513:D7D53_RS02870 ^@ http://purl.uniprot.org/uniprot/A0A387B398 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 5 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1433513:D7D53_RS05755 ^@ http://purl.uniprot.org/uniprot/A0A387B447 ^@ Similarity ^@ Belongs to the UPF0213 family. http://togogenome.org/gene/1433513:D7D53_RS00055 ^@ http://purl.uniprot.org/uniprot/A0A387B1S9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1433513:D7D53_RS03530 ^@ http://purl.uniprot.org/uniprot/A0A387B1J9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/1433513:D7D53_RS08515 ^@ http://purl.uniprot.org/uniprot/A0A387BCZ6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1433513:D7D53_RS09370 ^@ http://purl.uniprot.org/uniprot/A0A387B4K0 ^@ Activity Regulation|||Function|||PTM|||Similarity|||Subunit ^@ Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).|||Belongs to the FGGY kinase family.|||Homotetramer and homodimer (in equilibrium).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme. http://togogenome.org/gene/1433513:D7D53_RS03100 ^@ http://purl.uniprot.org/uniprot/A0A387B2N9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1433513:D7D53_RS07545 ^@ http://purl.uniprot.org/uniprot/A0A387AYV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0053 family.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS05340 ^@ http://purl.uniprot.org/uniprot/A0A387B0M2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1433513:D7D53_RS05785 ^@ http://purl.uniprot.org/uniprot/A0A387AY12 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/1433513:D7D53_RS03500 ^@ http://purl.uniprot.org/uniprot/A0A387AX11 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1433513:D7D53_RS04875 ^@ http://purl.uniprot.org/uniprot/A0A387B3N3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS06975 ^@ http://purl.uniprot.org/uniprot/A0A387AYL2 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. http://togogenome.org/gene/1433513:D7D53_RS01255 ^@ http://purl.uniprot.org/uniprot/A0A387AVZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1433513:D7D53_RS05475 ^@ http://purl.uniprot.org/uniprot/A0A387B2H5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/1433513:D7D53_RS08115 ^@ http://purl.uniprot.org/uniprot/A0A387B3Z8 ^@ Function|||Similarity ^@ Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.|||Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate. http://togogenome.org/gene/1433513:D7D53_RS00455 ^@ http://purl.uniprot.org/uniprot/A0A387B045 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1433513:D7D53_RS01095 ^@ http://purl.uniprot.org/uniprot/A0A387B1K5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1433513:D7D53_RS05480 ^@ http://purl.uniprot.org/uniprot/A0A387B3Z6 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1433513:D7D53_RS04210 ^@ http://purl.uniprot.org/uniprot/A0A387B081 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.|||Cytoplasm|||Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. http://togogenome.org/gene/1433513:D7D53_RS07075 ^@ http://purl.uniprot.org/uniprot/A0A387BC93 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as a pheromone, induces cells to develop competence for genetic transformation.|||Belongs to the ComC family.|||Secreted http://togogenome.org/gene/1433513:D7D53_RS09380 ^@ http://purl.uniprot.org/uniprot/A0A387B2L4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS03980 ^@ http://purl.uniprot.org/uniprot/A0A387AX79 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1433513:D7D53_RS00070 ^@ http://purl.uniprot.org/uniprot/A0A387B136 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/1433513:D7D53_RS01500 ^@ http://purl.uniprot.org/uniprot/A0A387B2K7 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1433513:D7D53_RS03080 ^@ http://purl.uniprot.org/uniprot/A0A387B2P2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/1433513:D7D53_RS01860 ^@ http://purl.uniprot.org/uniprot/A0A387B0M5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/1433513:D7D53_RS00010 ^@ http://purl.uniprot.org/uniprot/A0A387AZG6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1433513:D7D53_RS09185 ^@ http://purl.uniprot.org/uniprot/A0A387B2T5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1433513:D7D53_RS04845 ^@ http://purl.uniprot.org/uniprot/A0A387B0D7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1433513:D7D53_RS09620 ^@ http://purl.uniprot.org/uniprot/A0A387B696 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein S18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/1433513:D7D53_RS09605 ^@ http://purl.uniprot.org/uniprot/A0A387B6I6 ^@ Function|||Similarity|||Subunit ^@ A non-essential component of RNA polymerase (RNAP).|||Belongs to the RNA polymerase subunit epsilon family.|||RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1433513:D7D53_RS02710 ^@ http://purl.uniprot.org/uniprot/A0A387B2G4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrcB (TC 9.B.71) family.|||Cell membrane|||Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS02490 ^@ http://purl.uniprot.org/uniprot/A0A387AWJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1433513:D7D53_RS04575 ^@ http://purl.uniprot.org/uniprot/A0A387BAT2 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/1433513:D7D53_RS01080 ^@ http://purl.uniprot.org/uniprot/A0A387AYL3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 32 family.|||Cytoplasm|||Enables the bacterium to metabolize sucrose as a sole carbon source. http://togogenome.org/gene/1433513:D7D53_RS03825 ^@ http://purl.uniprot.org/uniprot/A0A387B3T2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/1433513:D7D53_RS09025 ^@ http://purl.uniprot.org/uniprot/A0A387B483 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm|||Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi. http://togogenome.org/gene/1433513:D7D53_RS01195 ^@ http://purl.uniprot.org/uniprot/A0A387AVY6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MrnC RNase family.|||Cytoplasm|||Homodimer.|||Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors. http://togogenome.org/gene/1433513:D7D53_RS06255 ^@ http://purl.uniprot.org/uniprot/A0A387B361 ^@ Function|||Similarity ^@ Belongs to the class-I DAHP synthase family.|||Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). http://togogenome.org/gene/1433513:D7D53_RS06340 ^@ http://purl.uniprot.org/uniprot/A0A387B545 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1433513:D7D53_RS00480 ^@ http://purl.uniprot.org/uniprot/A0A387B219 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1433513:D7D53_RS00405 ^@ http://purl.uniprot.org/uniprot/A0A387AVN7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1433513:D7D53_RS07315 ^@ http://purl.uniprot.org/uniprot/A0A387B5J8 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/1433513:D7D53_RS05405 ^@ http://purl.uniprot.org/uniprot/A0A387B3X2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1433513:D7D53_RS09550 ^@ http://purl.uniprot.org/uniprot/A0A387B6H6 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/1433513:D7D53_RS07265 ^@ http://purl.uniprot.org/uniprot/A0A387B1V3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0154 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1433513:D7D53_RS09955 ^@ http://purl.uniprot.org/uniprot/A0A387AZV8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1433513:D7D53_RS00215 ^@ http://purl.uniprot.org/uniprot/A0A387AVL3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/1433513:D7D53_RS02455 ^@ http://purl.uniprot.org/uniprot/A0A387AZC4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/1433513:D7D53_RS09255 ^@ http://purl.uniprot.org/uniprot/A0A387BDD1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/1433513:D7D53_RS08520 ^@ http://purl.uniprot.org/uniprot/A0A387B454 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1433513:D7D53_RS08935 ^@ http://purl.uniprot.org/uniprot/A0A387B5Q4 ^@ Similarity ^@ Belongs to the beta-class carbonic anhydrase family. http://togogenome.org/gene/1433513:D7D53_RS09925 ^@ http://purl.uniprot.org/uniprot/A0A387B6N8 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1433513:D7D53_RS09360 ^@ http://purl.uniprot.org/uniprot/A0A387B646 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HSP33 family.|||Cytoplasm|||Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.|||Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive. http://togogenome.org/gene/1433513:D7D53_RS08270 ^@ http://purl.uniprot.org/uniprot/A0A387B5Z0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS01530 ^@ http://purl.uniprot.org/uniprot/A0A387AW36 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/1433513:D7D53_RS00065 ^@ http://purl.uniprot.org/uniprot/A0A387AZI0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1433513:D7D53_RS02595 ^@ http://purl.uniprot.org/uniprot/A0A387AZA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/1433513:D7D53_RS09840 ^@ http://purl.uniprot.org/uniprot/A0A387B6D9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/1433513:D7D53_RS05980 ^@ http://purl.uniprot.org/uniprot/A0A387AY52 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/1433513:D7D53_RS06530 ^@ http://purl.uniprot.org/uniprot/A0A387B308 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1433513:D7D53_RS07420 ^@ http://purl.uniprot.org/uniprot/A0A387AYT6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/1433513:D7D53_RS00465 ^@ http://purl.uniprot.org/uniprot/A0A387AYA4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1433513:D7D53_RS01160 ^@ http://purl.uniprot.org/uniprot/A0A387AYQ3 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/1433513:D7D53_RS03140 ^@ http://purl.uniprot.org/uniprot/A0A387AZR2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1433513:D7D53_RS06475 ^@ http://purl.uniprot.org/uniprot/A0A387B2Z7 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/1433513:D7D53_RS02305 ^@ http://purl.uniprot.org/uniprot/A0A387B0V3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/1433513:D7D53_RS05780 ^@ http://purl.uniprot.org/uniprot/A0A387B0U4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/1433513:D7D53_RS07235 ^@ http://purl.uniprot.org/uniprot/A0A387B3K5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ScpA family.|||Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.|||Cytoplasm|||Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. http://togogenome.org/gene/1433513:D7D53_RS01640 ^@ http://purl.uniprot.org/uniprot/A0A387B1W0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1433513:D7D53_RS04585 ^@ http://purl.uniprot.org/uniprot/A0A387AXH0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1433513:D7D53_RS03075 ^@ http://purl.uniprot.org/uniprot/A0A387AWT9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1433513:D7D53_RS07845 ^@ http://purl.uniprot.org/uniprot/A0A387B574 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1433513:D7D53_RS06295 ^@ http://purl.uniprot.org/uniprot/A0A387B2X2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/1433513:D7D53_RS07510 ^@ http://purl.uniprot.org/uniprot/A0A387B3H7 ^@ Function|||Similarity ^@ Belongs to the ABC transporter superfamily.|||Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. http://togogenome.org/gene/1433513:D7D53_RS02485 ^@ http://purl.uniprot.org/uniprot/A0A387AZ90 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/1433513:D7D53_RS00080 ^@ http://purl.uniprot.org/uniprot/A0A387AZY2 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1433513:D7D53_RS01905 ^@ http://purl.uniprot.org/uniprot/A0A387AZ34 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/1433513:D7D53_RS02695 ^@ http://purl.uniprot.org/uniprot/A0A387AWK7 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/1433513:D7D53_RS09330 ^@ http://purl.uniprot.org/uniprot/A0A387B2K6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane